+D GENES KO #

  KEGG Orthology (KO) - Candidatus Kaiserbacteria bacterium NC_groundwater_79_Ag_B-0.1um_58_26

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A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:kbn00010] D HYS26_03425 hypothetical protein K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9] D HYS26_03335 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11] D HYS26_03340 fructose-bisphosphate aldolase class I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D HYS26_00920 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D HYS26_04510 gap; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D HYS26_00925 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D HYS26_03780 2,3-diphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D HYS26_03540 histidine phosphatase family protein K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D HYS26_03790 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D HYS26_02560 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] C 00020 Citrate cycle (TCA cycle) C 00030 Pentose phosphate pathway [PATH:kbn00030] D HYS26_03425 hypothetical protein K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9] D HYS26_03655 zwf; glucose-6-phosphate dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D HYS26_03650 gnd; decarboxylating 6-phosphogluconate dehydrogenase K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] D HYS26_04500 hypothetical protein K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D HYS26_04465 transketolase family protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D HYS26_04470 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D HYS26_04505 RpiB/LacA/LacB family sugar-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] D HYS26_04595 hypothetical protein K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] D HYS26_02740 ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D HYS26_03340 fructose-bisphosphate aldolase class I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D HYS26_03335 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11] C 00040 Pentose and glucuronate interconversions [PATH:kbn00040] D HYS26_04725 hypothetical protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D HYS26_04500 hypothetical protein K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] C 00051 Fructose and mannose metabolism [PATH:kbn00051] D HYS26_03335 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11] D HYS26_03340 fructose-bisphosphate aldolase class I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D HYS26_00920 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D HYS26_04505 RpiB/LacA/LacB family sugar-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] C 00052 Galactose metabolism D HYS26_04760 NAD-dependent epimerase/dehydratase family protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] C 00053 Ascorbate and aldarate metabolism D HYS26_04725 hypothetical protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] C 00500 Starch and sucrose metabolism D HYS26_03425 hypothetical protein K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:kbn00520] D HYS26_02080 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D HYS26_00005 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D HYS26_04860 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D HYS26_03430 murB; UDP-N-acetylmuramate dehydrogenase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D HYS26_04690 UDP-N-acetyl glucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D HYS26_02510 nucleotide sugar dehydrogenase K13015 wbpA; UDP-N-acetyl-D-glucosamine dehydrogenase [EC:1.1.1.136] D HYS26_04705 SDR family NAD(P)-dependent oxidoreductase K15894 pseB; UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase [EC:4.2.1.115 5.1.3.-] D HYS26_04610 acylneuraminate cytidylyltransferase family protein K18431 legF; CMP-N,N'-diacetyllegionaminic acid synthase [EC:2.7.7.82] D HYS26_04680 NAD-dependent epimerase/dehydratase family protein K08678 UXS1; UDP-glucuronate decarboxylase [EC:4.1.1.35] D HYS26_04725 hypothetical protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D HYS26_04760 NAD-dependent epimerase/dehydratase family protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D HYS26_03425 hypothetical protein K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9] C 00620 Pyruvate metabolism [PATH:kbn00620] D HYS26_00290 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D HYS26_01425 NADP-dependent malic enzyme K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D HYS26_00205 ppcA; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D HYS26_02560 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:kbn00630] D HYS26_01895 HAD family hydrolase K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18] D HYS26_02360 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00640 Propanoate metabolism C 00650 Butanoate metabolism C 00660 C5-Branched dibasic acid metabolism C 00562 Inositol phosphate metabolism [PATH:kbn00562] D HYS26_03625 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D HYS26_00920 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:kbn00190] D HYS26_02870 F0F1 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D HYS26_02895 atpD; F0F1 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D HYS26_02875 atpG; ATP synthase F1 subunit gamma K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D HYS26_02865 F0F1 ATP synthase subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D HYS26_02900 F0F1 ATP synthase subunit epsilon K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D HYS26_02850 atpB; F0F1 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a D HYS26_02860 atpF; F0F1 ATP synthase subunit B K02109 ATPF0B; F-type H+-transporting ATPase subunit b D HYS26_02855 atpE; ATP synthase F0 subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c D HYS26_00870 inorganic diphosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation by Calvin cycle [PATH:kbn00710] D HYS26_00925 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D HYS26_04510 gap; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D HYS26_03340 fructose-bisphosphate aldolase class I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D HYS26_03335 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11] D HYS26_04465 transketolase family protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D HYS26_04470 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D HYS26_04505 RpiB/LacA/LacB family sugar-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] D HYS26_00920 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D HYS26_04500 hypothetical protein K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D HYS26_00205 ppcA; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] C 00720 Other carbon fixation pathways [PATH:kbn00720] D HYS26_02560 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D HYS26_00205 ppcA; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] C 00680 Methane metabolism [PATH:kbn00680] D HYS26_02360 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D HYS26_03790 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D HYS26_00205 ppcA; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D HYS26_03340 fructose-bisphosphate aldolase class I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D HYS26_03335 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11] D HYS26_02560 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D HYS26_03780 2,3-diphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D HYS26_03540 histidine phosphatase family protein K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] C 00910 Nitrogen metabolism [PATH:kbn00910] D HYS26_01855 nirK; nitrite reductase, copper-containing K00368 nirK; nitrite reductase (NO-forming) [EC:1.7.2.1] D HYS26_03635 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] C 00920 Sulfur metabolism D HYS26_04645 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis C 00062 Fatty acid elongation C 00071 Fatty acid degradation C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism C 00564 Glycerophospholipid metabolism D HYS26_02490 adenylyltransferase/cytidyltransferase family protein K00980 tagD; glycerol-3-phosphate cytidylyltransferase [EC:2.7.7.39] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:kbn00230] D HYS26_02740 ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D HYS26_03555 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D HYS26_01290 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D HYS26_04855 hypothetical protein K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D HYS26_01500 purT; formate-dependent phosphoribosylglycinamide formyltransferase K08289 purT; phosphoribosylglycinamide formyltransferase 2 [EC:6.3.1.21] D HYS26_02410 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D HYS26_02405 phosphoribosylformylglycinamidine synthase K23270 purSL; phosphoribosylformylglycinamidine synthase subunit PurSL [EC:6.3.5.3] D HYS26_02420 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D HYS26_02415 purE; 5-(carboxyamino)imidazole ribonucleotide mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D HYS26_02425 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D HYS26_02430 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D HYS26_03995 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D HYS26_01680 IMP dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D HYS26_01305 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D HYS26_02885 rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D HYS26_02775 guaA; glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D HYS26_01275 hypothetical protein K00942 gmk; guanylate kinase [EC:2.7.4.8] D HYS26_02215 ribonucleoside-triphosphate reductase K00527 rtpR; ribonucleoside-triphosphate reductase (thioredoxin) [EC:1.17.4.2] D HYS26_03755 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D HYS26_00585 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D HYS26_02825 carbohydrate kinase family protein K00856 ADK; adenosine kinase [EC:2.7.1.20] D HYS26_01280 nucleoside monophosphate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00240 Pyrimidine metabolism [PATH:kbn00240] D HYS26_03415 carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D HYS26_03410 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D HYS26_01420 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D HYS26_01415 pyrC; dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3] D HYS26_04005 orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D HYS26_04010 pyrF; orotidine-5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D HYS26_01305 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D HYS26_01670 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2] D HYS26_02215 ribonucleoside-triphosphate reductase K00527 rtpR; ribonucleoside-triphosphate reductase (thioredoxin) [EC:1.17.4.2] D HYS26_02385 dcd; dCTP deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13] D HYS26_02370 hypothetical protein K01493 comEB; dCMP deaminase [EC:3.5.4.12] D HYS26_02365 tmk; dTMP kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D HYS26_02375 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:kbn00250] D HYS26_02520 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D HYS26_04625 asnB; asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D HYS26_03580 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D HYS26_03560 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D HYS26_00585 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D HYS26_02430 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D HYS26_01420 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D HYS26_03635 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D HYS26_03415 carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D HYS26_03410 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D HYS26_02410 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D HYS26_02080 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D HYS26_03555 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:kbn00260] D HYS26_03665 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D HYS26_03660 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D HYS26_01355 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D HYS26_02360 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D HYS26_03780 2,3-diphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D HYS26_03540 histidine phosphatase family protein K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D HYS26_03350 glycine C-acetyltransferase K00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29] D HYS26_03360 zinc-binding dehydrogenase K00060 tdh; threonine 3-dehydrogenase [EC:1.1.1.103] C 00270 Cysteine and methionine metabolism [PATH:kbn00270] D HYS26_04645 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D HYS26_02090 metK; methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D HYS26_02830 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D HYS26_03665 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D HYS26_03660 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D HYS26_03875 aminotransferase class IV K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D HYS26_02520 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] C 00280 Valine, leucine and isoleucine degradation [PATH:kbn00280] D HYS26_03875 aminotransferase class IV K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:kbn00290] D HYS26_00785 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D HYS26_03875 aminotransferase class IV K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] C 00300 Lysine biosynthesis [PATH:kbn00300] D HYS26_03665 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D HYS26_03660 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D HYS26_03075 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D HYS26_03070 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] D HYS26_03080 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D HYS26_03085 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D HYS26_00380 murE; UDP-N-acetylmuramyl-tripeptide synthetase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D HYS26_02800 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] C 00310 Lysine degradation C 00220 Arginine biosynthesis [PATH:kbn00220] D HYS26_03580 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D HYS26_03560 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D HYS26_03575 hypothetical protein K27545 argZ; arginine dihydrolase [EC:3.5.3.27] D HYS26_02410 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D HYS26_03415 carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D HYS26_03410 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D HYS26_03635 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D HYS26_02520 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] C 00330 Arginine and proline metabolism [PATH:kbn00330] D HYS26_00095 hypothetical protein K01585 speA; arginine decarboxylase [EC:4.1.1.19] D HYS26_00110 agmatinase family protein K01480 speB; agmatinase [EC:3.5.3.11] D HYS26_00105 carboxynorspermidine decarboxylase K13747 nspC; carboxynorspermidine decarboxylase [EC:4.1.1.96] D HYS26_03595 succinylglutamate desuccinylase/aspartoacylase family protein K05526 astE; succinylglutamate desuccinylase [EC:3.5.1.96] D HYS26_03575 hypothetical protein K27545 argZ; arginine dihydrolase [EC:3.5.3.27] D HYS26_02520 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] C 00340 Histidine metabolism [PATH:kbn00340] D HYS26_03605 hisG; ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17] D HYS26_03600 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE K11755 hisIE; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31] C 00350 Tyrosine metabolism D HYS26_02520 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] C 00360 Phenylalanine metabolism D HYS26_02520 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] C 00380 Tryptophan metabolism C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:kbn00400] D HYS26_04485 3-deoxy-7-phosphoheptulonate synthase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D HYS26_04480 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4] D HYS26_04495 3-dehydroquinate dehydratase K03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10] D HYS26_04490 aroE; shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D HYS26_04020 AAA family ATPase K00891 aroK; shikimate kinase [EC:2.7.1.71] D HYS26_02520 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism C 00430 Taurine and hypotaurine metabolism C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism D HYS26_00150 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism D HYS26_02360 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:kbn00470] D HYS26_03390 ATP-grasp domain-containing protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D HYS26_02410 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D HYS26_04800 aspartate/glutamate racemase family protein K01776 murI; glutamate racemase [EC:5.1.1.3] D HYS26_04805 hypothetical protein K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D HYS26_03085 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] C 00480 Glutathione metabolism [PATH:kbn00480] D HYS26_03650 gnd; decarboxylating 6-phosphogluconate dehydrogenase K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] D HYS26_03655 zwf; glucose-6-phosphate dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:kbn00541] D HYS26_04760 NAD-dependent epimerase/dehydratase family protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D HYS26_04725 hypothetical protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D HYS26_00010 NTP transferase domain-containing protein K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D HYS26_04700 sugar nucleotide-binding protein K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] D HYS26_04690 UDP-N-acetyl glucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D HYS26_04705 SDR family NAD(P)-dependent oxidoreductase K15894 pseB; UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase [EC:4.2.1.115 5.1.3.-] D HYS26_02510 nucleotide sugar dehydrogenase K13015 wbpA; UDP-N-acetyl-D-glucosamine dehydrogenase [EC:1.1.1.136] C 00550 Peptidoglycan biosynthesis [PATH:kbn00550] D HYS26_04860 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D HYS26_03430 murB; UDP-N-acetylmuramate dehydrogenase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D HYS26_04795 UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D HYS26_04805 hypothetical protein K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D HYS26_00380 murE; UDP-N-acetylmuramyl-tripeptide synthetase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D HYS26_03390 ATP-grasp domain-containing protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D HYS26_02800 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D HYS26_03505 diacylglycerol kinase family protein K00887 dgkA; undecaprenol kinase [EC:2.7.1.66] D HYS26_03515 undecaprenyl-diphosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D HYS26_03510 phosphatase PAP2 family protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D HYS26_03035 hypothetical protein K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D HYS26_03025 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D HYS26_02685 hypothetical protein K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D HYS26_02795 penicillin-binding protein 2 K08384 spoVD; stage V sporulation protein D (sporulation-specific penicillin-binding protein) C 00552 Teichoic acid biosynthesis [PATH:kbn00552] D HYS26_03515 undecaprenyl-diphosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D HYS26_03510 phosphatase PAP2 family protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis [PATH:kbn00543] D HYS26_04645 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:kbn00730] D HYS26_03830 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D HYS26_01280 nucleoside monophosphate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism D HYS26_00335 adenylyltransferase/cytidyltransferase family protein K14656 ribL; FAD synthetase [EC:2.7.7.2] C 00750 Vitamin B6 metabolism [PATH:kbn00750] D HYS26_01355 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D HYS26_03375 pdxS; pyridoxal 5'-phosphate synthase lyase subunit PdxS K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6] D HYS26_03380 pdxT; pyridoxal 5'-phosphate synthase glutaminase subunit PdxT K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6] C 00760 Nicotinate and nicotinamide metabolism C 00770 Pantothenate and CoA biosynthesis [PATH:kbn00770] D HYS26_00785 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D HYS26_03875 aminotransferase class IV K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] C 00780 Biotin metabolism C 00785 Lipoic acid metabolism C 00790 Folate biosynthesis [PATH:kbn00790] D HYS26_02390 dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D HYS26_01515 4a-hydroxytetrahydrobiopterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] C 00670 One carbon pool by folate [PATH:kbn00670] D HYS26_02390 dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D HYS26_02360 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D HYS26_04855 hypothetical protein K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D HYS26_03995 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D HYS26_02620 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D HYS26_02375 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:kbn00860] D HYS26_03020 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D HYS26_00260 cob(I)yrinic acid a,c-diamide adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D HYS26_04465 transketolase family protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D HYS26_04470 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis [PATH:kbn00523] D HYS26_00010 NTP transferase domain-containing protein K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D HYS26_00005 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D HYS26_04700 sugar nucleotide-binding protein K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics D HYS26_04685 class I SAM-dependent methyltransferase K16437 evaC; methylation protein EvaC B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis C 00261 Monobactam biosynthesis [PATH:kbn00261] D HYS26_03665 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D HYS26_03660 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D HYS26_03075 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D HYS26_03070 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:kbn00521] D HYS26_03625 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D HYS26_00010 NTP transferase domain-containing protein K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D HYS26_00005 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D HYS26_04700 sugar nucleotide-binding protein K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 00524 Neomycin, kanamycin and gentamicin biosynthesis C 00525 Acarbose and validamycin biosynthesis D HYS26_00010 NTP transferase domain-containing protein K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D HYS26_00005 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] C 00401 Novobiocin biosynthesis D HYS26_02520 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis C 00333 Prodigiosin biosynthesis C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics C 00999 Biosynthesis of various plant secondary metabolites [PATH:kbn00999] D HYS26_02090 metK; methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D HYS26_04490 aroE; shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation C 00627 Aminobenzoate degradation D HYS26_00290 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation C 00361 Chlorocyclohexane and chlorobenzene degradation C 00623 Toluene degradation C 00622 Xylene degradation C 00633 Nitrotoluene degradation C 00642 Ethylbenzene degradation C 00643 Styrene degradation C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation C 00626 Naphthalene degradation C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:kbn03020] D HYS26_04240 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D HYS26_04235 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D HYS26_03150 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] C 03022 Basal transcription factors C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:kbn03010] D HYS26_03945 S1 RNA-binding domain-containing protein K02945 RP-S1; small subunit ribosomal protein S1 D HYS26_04430 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D HYS26_01205 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D HYS26_03155 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D HYS26_01260 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D HYS26_00130 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D HYS26_01010 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D HYS26_01245 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D HYS26_03135 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D HYS26_01080 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D HYS26_03160 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D HYS26_01005 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D HYS26_03165 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D HYS26_01240 type Z 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D HYS26_00740 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D HYS26_04265 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D HYS26_01220 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D HYS26_00120 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D HYS26_01195 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D HYS26_00370 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D HYS26_03970 hypothetical protein K02970 RP-S21; small subunit ribosomal protein S21 D HYS26_01190 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D HYS26_01175 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D HYS26_01180 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4 D HYS26_01235 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D HYS26_01250 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D HYS26_00025 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D HYS26_02975 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D HYS26_00030 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D HYS26_00190 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D HYS26_03140 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D HYS26_01225 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D HYS26_01265 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D HYS26_01210 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D HYS26_03145 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D HYS26_01255 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D HYS26_00285 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D HYS26_01325 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D HYS26_03290 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D HYS26_01200 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D HYS26_01185 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D HYS26_01230 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D HYS26_04450 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25 D HYS26_02980 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D HYS26_00985 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D HYS26_01215 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D HYS26_04440 type B 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D HYS26_04300 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D HYS26_03795 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D HYS26_00485 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D HYS26_03170 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 C 00970 Aminoacyl-tRNA biosynthesis [PATH:kbn00970] D HYS26_03020 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D HYS26_01600 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D HYS26_04560 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D HYS26_01595 aspartyl/glutamyl-tRNA amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D HYS26_03190 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D HYS26_03055 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D HYS26_00160 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D HYS26_04325 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D HYS26_03740 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D HYS26_02955 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D HYS26_00150 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D HYS26_02620 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D HYS26_04125 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D HYS26_00175 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D HYS26_03480 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D HYS26_00185 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D HYS26_02665 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D HYS26_02300 histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D HYS26_04400 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D HYS26_04390 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D HYS26_03460 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D HYS26_03060 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:kbn03060] D HYS26_01270 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D HYS26_00200 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE D HYS26_02150 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG D HYS26_00495 membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase D HYS26_04565 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D HYS26_03960 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D HYS26_04530 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:kbn04122] D HYS26_03830 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D HYS26_03250 mnmA; tRNA 2-thiouridine(34) synthase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] C 03050 Proteasome C 03018 RNA degradation [PATH:kbn03018] D HYS26_03790 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D HYS26_00720 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D HYS26_01975 DEAD/DEAH box helicase K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] D HYS26_00850 rny; ribonuclease Y K18682 rny; ribonucrease Y [EC:3.1.-.-] D HYS26_02140 RNase J family beta-CASP ribonuclease K12574 rnj; ribonuclease J [EC:3.1.-.-] D HYS26_03120 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D HYS26_02165 groL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] B B 09124 Replication and repair C 03030 DNA replication [PATH:kbn03030] D HYS26_02990 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D HYS26_04315 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D HYS26_03710 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D HYS26_00475 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D HYS26_03270 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D HYS26_04225 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D HYS26_00125 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D HYS26_04305 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D HYS26_00420 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7] D HYS26_01590 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03410 Base excision repair [PATH:kbn03410] D HYS26_02115 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D HYS26_03210 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D HYS26_02130 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D HYS26_04075 DNA-3-methyladenine glycosylase 2 family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21] D HYS26_00800 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D HYS26_00420 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7] D HYS26_00940 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D HYS26_01590 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03420 Nucleotide excision repair [PATH:kbn03420] D HYS26_03420 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A D HYS26_03440 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B D HYS26_03400 UvrB/UvrC motif-containing protein K03703 uvrC; excinuclease ABC subunit C D HYS26_00575 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D HYS26_00420 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7] D HYS26_01590 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03430 Mismatch repair [PATH:kbn03430] D HYS26_00575 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D HYS26_00940 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D HYS26_00125 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D HYS26_04315 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D HYS26_00475 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D HYS26_03710 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D HYS26_02990 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D HYS26_01590 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03440 Homologous recombination [PATH:kbn03440] D HYS26_00940 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D HYS26_00125 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D HYS26_03275 recR; recombination protein RecR K06187 recR; recombination protein RecR D HYS26_00090 recA; recombinase RecA K03553 recA; recombination protein RecA D HYS26_00420 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7] D HYS26_00375 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA D HYS26_00440 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D HYS26_00465 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D HYS26_01445 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D HYS26_04315 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D HYS26_00475 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D HYS26_03710 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D HYS26_02990 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] C 03450 Non-homologous end-joining C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:kbn02010] D HYS26_01665 ABC transporter permease K09811 ftsX; cell division transport system permease protein D HYS26_01660 ftsE; cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein D HYS26_04110 ABC transporter ATP-binding protein K18893 vcaM; ATP-binding cassette, subfamily B, multidrug efflux pump C 02060 Phosphotransferase system (PTS) C 03070 Bacterial secretion system [PATH:kbn03070] D HYS26_00350 prepilin-type N-terminal cleavage/methylation domain-containing protein K02456 gspG; general secretion pathway protein G D HYS26_01560 type II secretion system protein K02456 gspG; general secretion pathway protein G D HYS26_01540 type II/IV secretion system protein K02454 gspE; general secretion pathway protein E [EC:7.4.2.8] D HYS26_00200 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE D HYS26_02150 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG D HYS26_01270 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D HYS26_00495 membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase D HYS26_04565 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] B B 09132 Signal transduction C 02020 Two-component system [PATH:kbn02020] D HYS26_00480 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein D HYS26_00750 winged helix-turn-helix transcriptional regulator K14981 chvI; two-component system, OmpR family, response regulator ChvI D HYS26_01425 NADP-dependent malic enzyme K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D HYS26_02810 Flp family type IVb pilin K02651 flp; pilus assembly protein Flp/PilA D HYS26_02745 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1 D HYS26_01545 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D HYS26_04690 UDP-N-acetyl glucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:kbn02024] D HYS26_04485 3-deoxy-7-phosphoheptulonate synthase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D HYS26_02145 hypothetical protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D HYS26_00495 membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase D HYS26_00200 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE D HYS26_02150 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG D HYS26_01270 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D HYS26_04565 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis D HYS26_01545 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY C 02040 Flagellar assembly D HYS26_04220 sigma-70 family RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D HYS26_03790 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism D HYS26_00260 cob(I)yrinic acid a,c-diamide adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance D HYS26_02685 hypothetical protein K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] C 01502 Vancomycin resistance [PATH:kbn01502] D HYS26_03390 ATP-grasp domain-containing protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D HYS26_02800 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D HYS26_03035 hypothetical protein K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D HYS26_03025 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:kbn01503] D HYS26_00645 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:kbn01000] C 01001 Protein kinases C 01009 Protein phosphatases and associated proteins [BR:kbn01009] D HYS26_02830 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] C 01002 Peptidases and inhibitors [BR:kbn01002] D HYS26_01565 prepilin peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D HYS26_02775 guaA; glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D HYS26_03555 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D HYS26_02080 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D HYS26_04625 asnB; asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D HYS26_04365 sortase K07284 srtA; sortase A [EC:3.4.22.70] D HYS26_01285 map; type I methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D HYS26_03545 aminopeptidase K19689 ampS; aminopeptidase [EC:3.4.11.-] D HYS26_01410 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D HYS26_02185 M48 family metallopeptidase K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D HYS26_02660 RIP metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] D HYS26_04130 PrsW family intramembrane metalloprotease K24131 prsW; protease PrsW [EC:3.4.-.-] D HYS26_00855 clpP; ATP-dependent Clp endopeptidase proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D HYS26_04095 ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D HYS26_00700 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D HYS26_01360 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D HYS26_03960 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D HYS26_04530 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D HYS26_02965 S41 family peptidase K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] D HYS26_00950 S49 family peptidase K04773 sppA; protease IV [EC:3.4.21.-] C 01003 Glycosyltransferases [BR:kbn01003] D HYS26_02505 glycosyltransferase family 2 protein K00752 hasA; hyaluronan synthase [EC:2.4.1.212] C 01005 Lipopolysaccharide biosynthesis proteins C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:kbn01011] D HYS26_04860 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D HYS26_03430 murB; UDP-N-acetylmuramate dehydrogenase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D HYS26_04795 UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D HYS26_04805 hypothetical protein K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D HYS26_00380 murE; UDP-N-acetylmuramyl-tripeptide synthetase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D HYS26_03390 ATP-grasp domain-containing protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D HYS26_04800 aspartate/glutamate racemase family protein K01776 murI; glutamate racemase [EC:5.1.1.3] D HYS26_03035 hypothetical protein K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D HYS26_03025 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D HYS26_03515 undecaprenyl-diphosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D HYS26_03510 phosphatase PAP2 family protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D HYS26_02240 hypothetical protein K03980 murJ; putative peptidoglycan lipid II flippase D HYS26_02685 hypothetical protein K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D HYS26_02795 penicillin-binding protein 2 K08384 spoVD; stage V sporulation protein D (sporulation-specific penicillin-binding protein) D HYS26_04365 sortase K07284 srtA; sortase A [EC:3.4.22.70] D HYS26_03255 mltG; endolytic transglycosylase MltG K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] D HYS26_00645 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] C 01004 Lipid biosynthesis proteins C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:kbn01006] D HYS26_03775 miaA; tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] C 01007 Amino acid related enzymes [BR:kbn01007] D HYS26_03020 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D HYS26_03460 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D HYS26_03060 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D HYS26_02955 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D HYS26_00185 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D HYS26_00150 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D HYS26_00175 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D HYS26_04125 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D HYS26_03480 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D HYS26_03055 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D HYS26_02300 histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D HYS26_00160 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D HYS26_03740 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D HYS26_02665 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D HYS26_04325 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D HYS26_03190 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D HYS26_04400 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D HYS26_04390 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D HYS26_02520 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D HYS26_03080 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D HYS26_03350 glycine C-acetyltransferase K00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29] D HYS26_03875 aminotransferase class IV K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins [BR:kbn00194] D HYS26_02900 F0F1 ATP synthase subunit epsilon K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D HYS26_02895 atpD; F0F1 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D HYS26_02875 atpG; ATP synthase F1 subunit gamma K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D HYS26_02870 F0F1 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D HYS26_02865 F0F1 ATP synthase subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D HYS26_02860 atpF; F0F1 ATP synthase subunit B K02109 ATPF0B; F-type H+-transporting ATPase subunit b D HYS26_02855 atpE; ATP synthase F0 subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c D HYS26_02850 atpB; F0F1 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:kbn03000] D HYS26_03500 transcriptional repressor K22297 furA; Fur family transcriptional regulator, stress-responsive regulator D HYS26_02735 helix-turn-helix transcriptional regulator K07727 K07727; putative transcriptional regulator D HYS26_02335 helix-turn-helix transcriptional regulator K07729 K07729; putative transcriptional regulator D HYS26_01755 metal-sensitive transcriptional regulator K21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor D HYS26_03760 ParB/RepB/Spo0J family partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D HYS26_02780 mraZ; division/cell wall cluster transcriptional repressor MraZ K03925 mraZ; transcriptional regulator MraZ C 03021 Transcription machinery [BR:kbn03021] D HYS26_03150 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D HYS26_04240 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D HYS26_04235 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D HYS26_04220 sigma-70 family RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor D HYS26_01880 RNA polymerase sigma factor K03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily D HYS26_03345 hypothetical protein K03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily D HYS26_00880 nusA; transcription termination/antitermination protein NusA K02600 nusA; transcription termination/antitermination protein NusA D HYS26_00195 nusG; transcription termination/antitermination factor NusG K02601 nusG; transcription termination/antitermination protein NusG D HYS26_02690 greA; transcription elongation factor GreA K03624 greA; transcription elongation factor GreA C 03019 Messenger RNA biogenesis [BR:kbn03019] D HYS26_04290 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D HYS26_02140 RNase J family beta-CASP ribonuclease K12574 rnj; ribonuclease J [EC:3.1.-.-] D HYS26_00850 rny; ribonuclease Y K18682 rny; ribonucrease Y [EC:3.1.-.-] D HYS26_01975 DEAD/DEAH box helicase K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] D HYS26_03790 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D HYS26_00720 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D HYS26_03120 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D HYS26_02165 groL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] C 03041 Spliceosome C 03011 Ribosome [BR:kbn03011] D HYS26_03945 S1 RNA-binding domain-containing protein K02945 RP-S1; small subunit ribosomal protein S1 D HYS26_04430 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D HYS26_01205 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D HYS26_03155 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D HYS26_01260 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D HYS26_00130 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D HYS26_01010 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D HYS26_01245 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D HYS26_03135 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D HYS26_01080 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D HYS26_03160 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D HYS26_01005 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D HYS26_03165 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D HYS26_01240 type Z 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D HYS26_00740 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D HYS26_04265 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D HYS26_01220 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D HYS26_00120 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D HYS26_01195 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D HYS26_00370 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D HYS26_03970 hypothetical protein K02970 RP-S21; small subunit ribosomal protein S21 D HYS26_01190 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D HYS26_01175 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D HYS26_01180 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4 D HYS26_01235 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D HYS26_01250 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D HYS26_02975 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D HYS26_00030 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D HYS26_00190 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D HYS26_00025 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D HYS26_03140 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D HYS26_01225 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D HYS26_01265 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D HYS26_01210 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D HYS26_03145 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D HYS26_01255 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D HYS26_00285 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D HYS26_01325 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D HYS26_03290 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D HYS26_01200 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D HYS26_01185 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D HYS26_01230 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D HYS26_02980 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D HYS26_00985 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D HYS26_01215 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D HYS26_04440 type B 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D HYS26_04300 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D HYS26_03795 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D HYS26_00485 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D HYS26_03170 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 D HYS26_04450 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25 C 03009 Ribosome biogenesis [BR:kbn03009] D HYS26_04290 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D HYS26_00880 nusA; transcription termination/antitermination protein NusA K02600 nusA; transcription termination/antitermination protein NusA D HYS26_00195 nusG; transcription termination/antitermination factor NusG K02601 nusG; transcription termination/antitermination protein NusG D HYS26_00570 rsmA; ribosomal RNA small subunit methyltransferase A K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D HYS26_02785 rsmH; 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D HYS26_04790 rsmI; 16S rRNA (cytidine(1402)-2'-O)-methyltransferase K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D HYS26_00330 pre-16S rRNA-processing nuclease YqgF K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-] D HYS26_03755 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D HYS26_03840 ribosome-binding factor A K02834 rbfA; ribosome-binding factor A D HYS26_03975 ybeY; rRNA maturation RNase YbeY K07042 ybeY; probable rRNA maturation factor D HYS26_02615 HPF/RaiA family ribosome-associated protein K05808 hpf; ribosome hibernation promoting factor D HYS26_02930 ychF; redox-regulated ATPase YchF K06942 ychF; ribosome-binding ATPase C 03016 Transfer RNA biogenesis [BR:kbn03016] D HYS26_00805 HD domain-containing protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] D HYS26_03020 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D HYS26_02665 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D HYS26_00175 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D HYS26_00150 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D HYS26_00185 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D HYS26_03480 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D HYS26_03190 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D HYS26_00160 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D HYS26_04325 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D HYS26_03740 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D HYS26_02955 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D HYS26_04125 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D HYS26_02300 histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D HYS26_04400 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D HYS26_04390 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D HYS26_03460 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D HYS26_03060 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D HYS26_00935 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D HYS26_03830 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D HYS26_03775 miaA; tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D HYS26_00490 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5] D HYS26_03055 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D HYS26_04250 trmD; tRNA (guanosine(37)-N1)-methyltransferase TrmD K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D HYS26_03250 mnmA; tRNA 2-thiouridine(34) synthase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D HYS26_04115 tsaD; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234] D HYS26_00720 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] C 03012 Translation factors [BR:kbn03012] D HYS26_03835 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D HYS26_01335 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D HYS26_04425 tsf; elongation factor Ts K02357 tsf; elongation factor Ts D HYS26_01060 tuf; elongation factor Tu K02358 tuf; elongation factor Tu D HYS26_01025 fusA; elongation factor G K02355 fusA; elongation factor G D HYS26_04435 PCRF domain-containing protein K02835 prfA; peptide chain release factor 1 D HYS26_02655 frr; ribosome recycling factor K02838 frr; ribosome recycling factor D HYS26_03955 aminoacyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D HYS26_03175 infA; translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1 D HYS26_00115 hypothetical protein K02356 efp; elongation factor P D HYS26_01655 PCRF domain-containing protein K02836 prfB; peptide chain release factor 2 C 03110 Chaperones and folding catalysts [BR:kbn03110] D HYS26_03820 AAA family ATPase K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB D HYS26_03120 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D HYS26_02165 groL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D HYS26_03115 dnaJ; molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ D HYS26_03125 nucleotide exchange factor GrpE K03687 GRPE; molecular chaperone GrpE D HYS26_04135 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein D HYS26_02160 co-chaperone GroES K04078 groES; chaperonin GroES D HYS26_01410 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D HYS26_02850 atpB; F0F1 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a D HYS26_00745 FKBP-type peptidyl-prolyl cis-trans isomerase K03772 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8] C 04131 Membrane trafficking [BR:kbn04131] D HYS26_01305 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D HYS26_03340 fructose-bisphosphate aldolase class I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D HYS26_04510 gap; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D HYS26_03780 2,3-diphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] C 04121 Ubiquitin system C 03051 Proteasome C 03032 DNA replication proteins [BR:kbn03032] D HYS26_00845 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D HYS26_00480 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein D HYS26_03270 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D HYS26_04225 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D HYS26_00125 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D HYS26_04315 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D HYS26_00475 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D HYS26_02990 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D HYS26_03710 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D HYS26_04305 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D HYS26_00420 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7] D HYS26_01590 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D HYS26_03920 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D HYS26_04380 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D HYS26_03750 topA; type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1] C 03036 Chromosome and associated proteins [BR:kbn03036] D HYS26_04290 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D HYS26_03340 fructose-bisphosphate aldolase class I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D HYS26_00845 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D HYS26_00480 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein D HYS26_03050 segregation/condensation protein A K05896 scpA; segregation and condensation protein A D HYS26_03045 SMC-Scp complex subunit ScpB K06024 scpB; segregation and condensation protein B D HYS26_03980 ftsA; cell division protein FtsA K03590 ftsA; cell division protein FtsA D HYS26_01660 ftsE; cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein D HYS26_00080 DNA translocase FtsK K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family D HYS26_03735 hypothetical protein K03589 ftsQ; cell division protein FtsQ D HYS26_03030 FtsW/RodA/SpoVE family cell cycle protein K03588 ftsW; cell division protein FtsW D HYS26_01665 ABC transporter permease K09811 ftsX; cell division transport system permease protein D HYS26_03985 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D HYS26_00645 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D HYS26_02635 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins D HYS26_02670 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins D HYS26_02675 rod shape-determining protein MreC K03570 mreC; rod shape-determining protein MreC D HYS26_03760 ParB/RepB/Spo0J family partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D HYS26_00780 tyrosine-type recombinase/integrase K04763 xerD; integrase/recombinase XerD C 03400 DNA repair and recombination proteins [BR:kbn03400] D HYS26_03225 MGMT family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D HYS26_03210 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D HYS26_02130 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D HYS26_02115 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D HYS26_02890 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D HYS26_04075 DNA-3-methyladenine glycosylase 2 family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21] D HYS26_00800 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D HYS26_00940 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D HYS26_01590 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D HYS26_00420 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7] D HYS26_03420 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A D HYS26_03440 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B D HYS26_03400 UvrB/UvrC motif-containing protein K03703 uvrC; excinuclease ABC subunit C D HYS26_00575 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D HYS26_04240 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D HYS26_04235 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D HYS26_03150 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D HYS26_04315 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D HYS26_00475 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D HYS26_02990 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D HYS26_03710 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D HYS26_00125 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D HYS26_00090 recA; recombinase RecA K03553 recA; recombination protein RecA D HYS26_00375 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA D HYS26_00440 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D HYS26_00465 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D HYS26_01445 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D HYS26_03275 recR; recombination protein RecR K06187 recR; recombination protein RecR D HYS26_03920 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D HYS26_04380 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D HYS26_03750 topA; type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D HYS26_00845 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D HYS26_01365 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D HYS26_00700 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D HYS26_01360 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] C 03029 Mitochondrial biogenesis [BR:kbn03029] D HYS26_03835 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D HYS26_01335 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D HYS26_04425 tsf; elongation factor Ts K02357 tsf; elongation factor Ts D HYS26_01060 tuf; elongation factor Tu K02358 tuf; elongation factor Tu D HYS26_01025 fusA; elongation factor G K02355 fusA; elongation factor G D HYS26_03460 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D HYS26_00160 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D HYS26_00185 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D HYS26_01600 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D HYS26_04560 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D HYS26_01595 aspartyl/glutamyl-tRNA amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D HYS26_00125 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D HYS26_03120 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D HYS26_03125 nucleotide exchange factor GrpE K03687 GRPE; molecular chaperone GrpE D HYS26_02165 groL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D HYS26_02160 co-chaperone GroES K04078 groES; chaperonin GroES D HYS26_03115 dnaJ; molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ D HYS26_03830 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D HYS26_00495 membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:kbn02000] D HYS26_04110 ABC transporter ATP-binding protein K18893 vcaM; ATP-binding cassette, subfamily B, multidrug efflux pump D HYS26_03905 extracellular solute-binding protein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D HYS26_02145 hypothetical protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D HYS26_01665 ABC transporter permease K09811 ftsX; cell division transport system permease protein D HYS26_01660 ftsE; cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein D HYS26_01905 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein D HYS26_02440 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein D HYS26_01900 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D HYS26_02450 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D HYS26_01865 ABC transporter permease K02004 ABC.CD.P; putative ABC transport system permease protein D HYS26_01870 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D HYS26_00960 MscL family protein K03282 mscL; large conductance mechanosensitive channel D HYS26_02960 hypothetical protein K03284 corA; magnesium transporter D HYS26_03495 ZIP family metal transporter K07238 TC.ZIP; zinc transporter, ZIP family D HYS26_01090 hypothetical protein K14392 panF; sodium/pantothenate symporter D HYS26_02240 hypothetical protein K03980 murJ; putative peptidoglycan lipid II flippase D HYS26_03205 LysE family transporter K05835 rhtC; threonine efflux protein D HYS26_04825 queuosine precursor transporter K09125 yhhQ; queuosine precursor transporter D HYS26_02310 VIT family protein K22737 mbfA; erythrin-vacuolar iron transport family protein D HYS26_03030 FtsW/RodA/SpoVE family cell cycle protein K03588 ftsW; cell division protein FtsW D HYS26_04050 hypothetical protein K15383 K15383; MtN3 and saliva related transmembrane protein D HYS26_03240 MgtC/SapB family protein K07507 mgtC; putative Mg2+ transporter-C (MgtC) family protein C 02044 Secretion system [BR:kbn02044] D HYS26_01540 type II/IV secretion system protein K02454 gspE; general secretion pathway protein E [EC:7.4.2.8] D HYS26_00350 prepilin-type N-terminal cleavage/methylation domain-containing protein K02456 gspG; general secretion pathway protein G D HYS26_01560 type II secretion system protein K02456 gspG; general secretion pathway protein G D HYS26_01565 prepilin peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D HYS26_00435 type II/IV secretion system protein K02652 pilB; type IV pilus assembly protein PilB D HYS26_00885 type II/IV secretion system protein K02652 pilB; type IV pilus assembly protein PilB D HYS26_00895 type II secretion system F family protein K02653 pilC; type IV pilus assembly protein PilC D HYS26_01555 type II secretion system F family protein K02653 pilC; type IV pilus assembly protein PilC D HYS26_00320 pilM; pilus assembly protein PilM K02662 pilM; type IV pilus assembly protein PilM D HYS26_01520 pilM; type IV pilus assembly protein PilM K02662 pilM; type IV pilus assembly protein PilM D HYS26_01550 PilT/PilU family type 4a pilus ATPase K02669 pilT; twitching motility protein PilT D HYS26_02810 Flp family type IVb pilin K02651 flp; pilus assembly protein Flp/PilA D HYS26_02370 hypothetical protein K01493 comEB; dCMP deaminase [EC:3.5.4.12] D HYS26_00965 ComEC/Rec2 family competence protein K02238 comEC; competence protein ComEC D HYS26_04565 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D HYS26_00200 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE D HYS26_02150 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG D HYS26_01270 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D HYS26_00495 membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase C 02042 Bacterial toxins C 02022 Two-component system [BR:kbn02022] D HYS26_00750 winged helix-turn-helix transcriptional regulator K14981 chvI; two-component system, OmpR family, response regulator ChvI D HYS26_01545 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY C 02035 Bacterial motility proteins [BR:kbn02035] D HYS26_01545 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D HYS26_01550 PilT/PilU family type 4a pilus ATPase K02669 pilT; twitching motility protein PilT D HYS26_00435 type II/IV secretion system protein K02652 pilB; type IV pilus assembly protein PilB D HYS26_00885 type II/IV secretion system protein K02652 pilB; type IV pilus assembly protein PilB D HYS26_00895 type II secretion system F family protein K02653 pilC; type IV pilus assembly protein PilC D HYS26_01555 type II secretion system F family protein K02653 pilC; type IV pilus assembly protein PilC D HYS26_01565 prepilin peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D HYS26_00320 pilM; pilus assembly protein PilM K02662 pilM; type IV pilus assembly protein PilM D HYS26_01520 pilM; type IV pilus assembly protein PilM K02662 pilM; type IV pilus assembly protein PilM D HYS26_02810 Flp family type IVb pilin K02651 flp; pilus assembly protein Flp/PilA C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:kbn04812] D HYS26_02635 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins D HYS26_02670 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins D HYS26_03985 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D HYS26_03980 ftsA; cell division protein FtsA K03590 ftsA; cell division protein FtsA D HYS26_03760 ParB/RepB/Spo0J family partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein C 04147 Exosome [BR:kbn04147] D HYS26_03340 fructose-bisphosphate aldolase class I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D HYS26_03790 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D HYS26_04510 gap; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D HYS26_00925 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D HYS26_02165 groL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D HYS26_03120 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK D HYS26_01680 IMP dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D HYS26_01060 tuf; elongation factor Tu K02358 tuf; elongation factor Tu D HYS26_00935 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D HYS26_02830 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D HYS26_01280 nucleoside monophosphate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D HYS26_03560 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D HYS26_03580 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D HYS26_01515 4a-hydroxytetrahydrobiopterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] D HYS26_03995 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D HYS26_03635 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D HYS26_03655 zwf; glucose-6-phosphate dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D HYS26_00920 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D HYS26_03780 2,3-diphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] C 02048 Prokaryotic defense system [BR:kbn02048] D HYS26_01475 DEAD/DEAH box helicase family protein K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D HYS26_01470 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D HYS26_00665 DNA adenine methylase K07318 K07318; adenine-specific DNA-methyltransferase [EC:2.1.1.72] D HYS26_01720 site-specific DNA-methyltransferase K07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72] D HYS26_03985 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D HYS26_02635 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins D HYS26_02670 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins D HYS26_03020 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D HYS26_03830 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules C 01504 Antimicrobial resistance genes C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins [BR:kbn03200] D HYS26_02815 hypothetical protein K14744 rzpD; prophage endopeptidase [EC:3.4.-.-] C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D HYS26_00100 saccharopine dehydrogenase family protein K27502 capadh; carboxyaminopropylagmatine dehydrogenase [EC:1.5.1.55] D HYS26_03990 FAD-dependent oxidoreductase K03387 ahpF; NADH-dependent peroxiredoxin subunit F [EC:1.8.1.-] D HYS26_03470 msrA; peptide-methionine (S)-S-oxide reductase MsrA K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D HYS26_01920 msrB; peptide-methionine (R)-S-oxide reductase MsrB K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] D HYS26_04180 hypothetical protein K12137 hyfB; hydrogenase-4 component B [EC:1.-.-.-] D HYS26_04170 hypothetical protein K12140 hyfE; hydrogenase-4 component E [EC:1.-.-.-] D HYS26_04165 hydrogenase 4 subunit F K12141 hyfF; hydrogenase-4 component F [EC:1.-.-.-] D HYS26_04880 cfa; cyclopropane fatty acyl phospholipid synthase K00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79] D HYS26_04215 GNAT family N-acetyltransferase K03830 yafP; putative acetyltransferase [EC:2.3.1.-] D HYS26_00135 TatD family hydrolase K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D HYS26_01345 thermonuclease family protein K01174 nuc; micrococcal nuclease [EC:3.1.31.1] D HYS26_02625 peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D HYS26_01800 copper-translocating P-type ATPase K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9] D HYS26_04040 HAD-IC family P-type ATPase K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10] C 99981 Carbohydrate metabolism C 99982 Energy metabolism C 99983 Lipid metabolism C 99984 Nucleotide metabolism C 99985 Amino acid metabolism C 99986 Glycan metabolism C 99987 Cofactor metabolism C 99988 Secondary metabolism C 99999 Others D HYS26_02695 DoxX family protein K15977 K15977; putative oxidoreductase B B 09192 Unclassified: genetic information processing C 99973 Transcription D HYS26_02580 cold shock domain-containing protein K03704 cspA; cold shock protein C 99974 Translation C 99975 Protein processing D HYS26_00860 hypothetical protein K03545 tig; trigger factor D HYS26_01405 smpB; SsrA-binding protein SmpB K03664 smpB; SsrA-binding protein D HYS26_00705 ATP-binding protein K07391 comM; magnesium chelatase family protein C 99976 Replication and repair D HYS26_03305 DNA recombination protein RmuC K09760 rmuC; DNA recombination protein RmuC D HYS26_00825 YraN family protein K07460 yraN; putative endonuclease D HYS26_01710 GIY-YIG nuclease family protein K07461 K07461; putative endonuclease D HYS26_02445 GIY-YIG nuclease family protein K07461 K07461; putative endonuclease D HYS26_03745 dprA; DNA-protecting protein DprA K04096 smf; DNA processing protein D HYS26_00755 replication-associated recombination protein A K07478 ycaJ; putative ATPase D HYS26_00535 transposase K07491 rayT; REP-associated tyrosine transposase D HYS26_01020 transposase K07491 rayT; REP-associated tyrosine transposase D HYS26_02535 transposase K07491 rayT; REP-associated tyrosine transposase D HYS26_04285 transposase K07491 rayT; REP-associated tyrosine transposase D HYS26_04460 transposase K07491 rayT; REP-associated tyrosine transposase D HYS26_04535 transposase K07491 rayT; REP-associated tyrosine transposase C 99979 Viral proteins C 99998 Others B B 09193 Unclassified: signaling and cellular processes C 99977 Transport C 99978 Cell growth D HYS26_00500 hypothetical protein K06346 jag; spoIIIJ-associated protein D HYS26_00615 recombinase family protein K06400 spoIVCA; site-specific DNA recombinase C 99993 Cell motility C 99995 Signaling proteins D HYS26_01915 typA; translational GTPase TypA K06207 typA; GTP-binding protein C 99992 Structural proteins D HYS26_01685 CapA family protein K07282 capA; gamma-polyglutamate biosynthesis protein CapA C 99994 Others B B 09194 Poorly characterized C 99996 General function prediction only D HYS26_00325 hypothetical protein K06878 K06878; tRNA-binding protein D HYS26_01495 LemA family protein K03744 lemA; LemA protein D HYS26_02175 LemA family protein K03744 lemA; LemA protein D HYS26_02355 HAD-IIB family hydrolase K03975 dedA; membrane-associated protein D HYS26_01455 phage holin family protein K08972 K08972; putative membrane protein C 99997 Function unknown D HYS26_01490 TPM domain-containing protein K06872 K06872; uncharacterized protein D HYS26_03680 stress-induced protein K06884 K06884; uncharacterized protein D HYS26_04475 DUF296 domain-containing protein K06934 K06934; uncharacterized protein D HYS26_04260 KH domain-containing protein K06960 K06960; uncharacterized protein D HYS26_02590 VOC family protein K06996 K06996; uncharacterized protein D HYS26_01745 sulfite exporter TauE/SafE family protein K07090 K07090; uncharacterized protein D HYS26_02305 SET domain-containing protein K07117 K07117; uncharacterized protein D HYS26_02210 DUF192 domain-containing protein K09005 K09005; uncharacterized protein D HYS26_03310 GatB/YqeY domain-containing protein K09117 K09117; uncharacterized protein D HYS26_02610 DUF167 domain-containing protein K09131 K09131; uncharacterized protein D HYS26_00730 DUF475 domain-containing protein K09799 K09799; uncharacterized protein D HYS26_00210 SIMPL domain-containing protein K09807 K09807; uncharacterized protein D HYS26_02460 DUF1993 domain-containing protein K09983 K09983; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: June 22, 2024