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Transfer RNA Biogenesis - Candidatus Kinetoplastidibacterium crithidiae (ex Angomonas deanei ATCC 30255)
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
C CCA adding factors
D CKCE_0532 tRNA nucleotidyltransferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D CKCE_0469 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D CKCE_0438 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D CKCE_0395 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D CKCE_0007 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D CKCE_0694 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D CKCE_0069 glnS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D CKCE_0616 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D CKCE_0370 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D CKCE_0546 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D CKCE_0215 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D CKCE_0402 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D CKCE_0098 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D CKCE_0778 cysteinyl-tRNA synthetase 2 K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D CKCE_0221 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D CKCE_0224 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D CKCE_0334 pheS; phenylalanyl-tRNA synthetase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D CKCE_0333 pheT; phenylalanyl-tRNA synthetase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D CKCE_0460 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D CKCE_0180 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
C AARS associated factors
D CKCE_0625 Hit-like protein involved in cell-cycle regulation K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
C Psudouridine synthases
D CKCE_0207 truB; tRNA pseudouridine55 synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
C Thiolation factors
D CKCE_0376 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D CKCE_0744 tRNA threonylcarbamoyladenosine biosynthesis protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D CKCE_0056 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D CKCE_0606 trmE; tRNA modification GTPase K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D CKCE_0605 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D CKCE_0608 rnpA; ribonuclease P K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D CKCE_0314 ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D CKCE_0477 exoribonuclease II K01147 rnb; exoribonuclease II [EC:3.1.13.1]
C CCA adding factors
D CKCE_0532 tRNA nucleotidyltransferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
D CKCE_0065 sulfate-transporting ATPase K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D CKCE_0007 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D CKCE_0438 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D CKCE_0460 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D CKCE_0180 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D CKCE_0402 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D CKCE_0395 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D CKCE_0370 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D CKCE_0215 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D CKCE_0221 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D CKCE_0694 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D CKCE_0098 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D CKCE_0546 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D CKCE_0050 glyQ; glycyl-tRNA synthetase subunit alpha K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D CKCE_0049 glyS; glycyl-tRNA synthetase subunit beta K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D CKCE_0778 cysteinyl-tRNA synthetase 2 K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D CKCE_0469 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D CKCE_0069 glnS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D CKCE_0616 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D CKCE_0334 pheS; phenylalanyl-tRNA synthetase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D CKCE_0333 pheT; phenylalanyl-tRNA synthetase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D CKCE_0224 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
C Trans-editing factors
B tRNA modification factors
C Deaminases
D CKCE_0365 tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
D CKCE_0410 tRNA-dihydrouridine synthase A K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
C Methylthiotransferases
D CKCE_0729 enzyme involved in thiolation and methylation of tRNA K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D CKCE_0772 lasT; tRNA/rRNA methyltransferase K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D CKCE_0219 trmD; methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D CKCE_0606 trmE; tRNA modification GTPase K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D CKCE_0494 tRNA (cytidine/uridine-2'-O-)-methyltransferase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
C Psudouridine synthases
D CKCE_0207 truB; tRNA pseudouridine55 synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
C Thiolation factors
D CKCE_0259 hypothetical protein K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D CKCE_0216 tRNA 2-thiouridine synthesizing protein A K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D CKCE_0374 iscA; iron-sulfur cluster assembly protein K13628 iscA; iron-sulfur cluster assembly protein
D CKCE_0376 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D CKCE_0287 hypothetical protein K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D CKCE_0605 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D CKCE_0056 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D CKCE_0721 hypothetical protein K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D CKCE_0734 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D CKCE_0686 queuosine biosynthesis protein QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D CKCE_0366 6-pyruvoyl tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D CKCE_0367 radical SAM superfamily protein 3 K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D CKCE_0014 queF; 7-cyano-7-deazaguanine reductase K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D CKCE_0211 hypothetical protein K09765 queH; epoxyqueuosine reductase [EC:1.17.99.6]
D CKCE_0733 queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D CKCE_0781 mesJ; tRNA(Ile)-lysidine synthase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D CKCE_0130 hypothetical protein K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D CKCE_0744 tRNA threonylcarbamoyladenosine biosynthesis protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D CKCE_0362 O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D CKCE_0059 ATPase YjeE protein K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D CKCE_0062 hypothetical protein K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C CKCE_0264 ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C CKCE_0106 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 17, 2025