+F Repair protein KO
#
DNA Repair and Recombination Proteins - Klebsiella michiganensis E718
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D A225_3235 Methylated-DNA-protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D A225_1728 Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E A225_4429 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E A225_4991 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E A225_3276 Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E A225_NDM1p0140 Putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D A225_0903 Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D A225_1517 Nudix hydrolase family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D A225_5661 Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D A225_3235 Methylated-DNA-protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D A225_4119 ADA regulatory protein / Methylated-DNA-protein-cysteine methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D A225_1728 Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D A225_4118 Alkylated DNA repair protein AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E A225_4429 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E A225_5080 G:T/U mismatch-specific uracil/thymine DNA-glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E A225_3904 DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E A225_4991 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E A225_5574 DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E A225_5656 Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E A225_1737 Endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E A225_3276 Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E A225_NDM1p0140 Putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E A225_2483 Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E A225_4056 Endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E A225_0256 Endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E A225_4914 Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E A225_4273 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E A225_5669 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E A225_0001 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E A225_0334 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E A225_1816 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E A225_3718 Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E A225_2492 Excinuclease cho (excinuclease ABC alternative C subunit) K05984 cho; excinuclease Cho [EC:3.1.25.-]
E A225_0185 ATP-dependent DNA helicase UvrD/PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E A225_0001 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E A225_4273 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E A225_5669 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F A225_0241 DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F A225_0242 DNA-directed RNA polymerase beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F A225_5312 DNA-directed RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F A225_5671 DNA-directed RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F A225_2333 Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E A225_4647 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E A225_0439 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E A225_4792 DNA mismatch repair endonuclease MutH K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E A225_3831 Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E A225_4359 Exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E A225_1253 Exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E A225_3656 Exodeoxyribonuclease X K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D DNA polymerase III holoenzyme
E A225_1014 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E A225_5787 DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E A225_0541 DNA polymerase III chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E A225_1670 DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E A225_2317 DNA polymerase III delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E A225_1048 DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E A225_1335 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E A225_0757 DNA polymerase III psi subunit K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
E A225_NDM1p0210 DNA polymerase III theta subunit K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
E A225_3655 DNA polymerase III theta subunit K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
D DNA ligase
E A225_4273 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E A225_5669 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E A225_0185 ATP-dependent DNA helicase UvrD/PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E A225_0335 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E A225_1451 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E A225_5380 Methyl-directed repair DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E A225_3784 Methyl-directed repair DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E A225_3737 Very-short-patch mismatch repair endonuclease (G-T specific) K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E A225_4779 Exodeoxyribonuclease V beta chain K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E A225_4781 Exodeoxyribonuclease V gamma chain K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E A225_4778 Exodeoxyribonuclease V alpha chain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E A225_4557 RecA protein K03553 recA; recombination protein RecA
E A225_3678 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E A225_3677 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E A225_3679 Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E A225_0097 Helicase PriA essential for oriC/DnaA-independent DNA replication K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E A225_1332 Primosomal replication protein N prime prime K04067 priC; primosomal replication protein N''
E A225_0741 Primosomal protein I K02317 dnaT; DNA replication protein DnaT
E A225_3831 Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E A225_1218 Exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E A225_1219 Exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E A225_4557 RecA protein K03553 recA; recombination protein RecA
E A225_0774 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E A225_5786 DNA recombination and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E A225_5674 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E A225_5705 putative transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E A225_4914 Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E A225_4415 DNA recombination and repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E A225_1337 Recombination protein RecR K06187 recR; recombination protein RecR
E A225_4467 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E A225_1215 DNA recombination-dependent growth factor C K03554 rdgC; recombination associated protein RdgC
E A225_3678 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E A225_3677 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E A225_3679 Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E A225_4677 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
E A225_4082 DNA or RNA helicase of superfamily II K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E A225_1218 Exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E A225_1219 Exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E A225_0546 hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F A225_4125 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F A225_5785 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F A225_2537 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F A225_0258 DNA-binding protein HU-alpha K05787 hupA; DNA-binding protein HU-alpha
F A225_1283 DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F A225_4914 Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F A225_4415 DNA recombination and repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F A225_1337 Recombination protein RecR K06187 recR; recombination protein RecR
F A225_4273 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F A225_5669 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F A225_5284 DNA-binding protein Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F A225_3460 Integration host factor alpha subunit K04764 ihfA; integration host factor subunit alpha
F A225_2041 Integration host factor beta subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F A225_3831 Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F A225_0190 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F A225_0334 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F A225_1816 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F A225_3493 DNA-binding protein H-NS K03746 hns; DNA-binding protein H-NS
F A225_R1p0120 DNA-binding protein H-NS K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D A225_1064 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D A225_2416 Error-prone K03502 umuC; DNA polymerase V
D A225_2685 Error-prone K03502 umuC; DNA polymerase V
D A225_NDM1p0120 UmuC K03502 umuC; DNA polymerase V
D A225_R1p0650 UmuC K03502 umuC; DNA polymerase V
D A225_2415 Error-prone repair protein UmuD K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D A225_2684 Error-prone repair protein UmuD K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D A225_R1p1010 UV protection protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D A225_NDM1p0085 UmnD K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D A225_4557 RecA protein K03553 recA; recombination protein RecA
D A225_0317 SOS-response repressor and protease LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D A225_2383 SOS-response repressor and protease LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D A225_4467 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D A225_0335 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D A225_1451 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D A225_2290 DNA-damage-inducible protein I K12149 dinI; DNA-damage-inducible protein I
D A225_1898 DNA-damage-inducible protein I K12149 dinI; DNA-damage-inducible protein I
D A225_4556 Regulatory protein RecX K03565 recX; regulatory protein
D A225_5736 Uncharacterized protein YfaD K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
D A225_0982 hypothetical protein K24088 rpnC; recombination-promoting nuclease RpnC [EC:3.1.21.-]
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D A225_0145 ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D A225_2085 DNA helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4]
D A225_1843 ATP-dependent helicase DinG/Rad3 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D A225_3605 DinG family ATP-dependent helicase YoaA K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D A225_0903 Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D A225_1517 Nudix hydrolase family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D A225_5661 Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D A225_4532 Ribonucleotide reductase of class Ib K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D A225_4127 Ribonucleotide reductase of class Ia K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D A225_4128 Ribonucleotide reductase of class Ia K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D A225_4533 Ribonucleotide reductase of class Ib K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024