+F Repair protein KO
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DNA Repair and Recombination Proteins - Kovacikia minuta
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D K9N68_16220 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D K9N68_20780 DNA photolyase family protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D K9N68_33675 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E K9N68_14985 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E K9N68_03310 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E K9N68_10200 Fe-S cluster assembly protein HesB K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E K9N68_01105 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D K9N68_30475 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D K9N68_27990 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D K9N68_16220 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D K9N68_30275 methylated-DNA--[protein]-cysteine S-methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D K9N68_20780 DNA photolyase family protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D K9N68_33675 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D K9N68_14100 cryptochrome/photolyase family protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E K9N68_06360 mug; G/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E K9N68_02030 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E K9N68_27880 DNA-3-methyladenine glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E K9N68_14985 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E K9N68_20540 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E K9N68_08695 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E K9N68_03310 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E K9N68_10200 Fe-S cluster assembly protein HesB K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E K9N68_01105 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E K9N68_18410 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E K9N68_04125 nfi; deoxyribonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E K9N68_02435 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E K9N68_19740 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E K9N68_00355 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E K9N68_33305 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
E K9N68_09245 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
E K9N68_16305 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F K9N68_15840 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F K9N68_15845 DNA-directed RNA polymerase subunit gamma K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F K9N68_33065 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F K9N68_05215 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E K9N68_04620 endonuclease MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E K9N68_00060 mutL; DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E K9N68_26970 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E K9N68_26965 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E K9N68_14705 trans-splicing intein-formed DNA polymerase III subunit alpha C-terminal partner DnaE-C K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E K9N68_02415 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E K9N68_20300 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E K9N68_20330 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E K9N68_36085 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E K9N68_26535 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
D Other MMR factors
E K9N68_16305 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E K9N68_06055 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E K9N68_28010 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E K9N68_37355 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E K9N68_07470 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E K9N68_36015 Dam family site-specific DNA-(adenine-N6)-methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E K9N68_34615 ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E K9N68_26975 recA; recombinase RecA K03553 recA; recombination protein RecA
E K9N68_14670 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E K9N68_31505 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E K9N68_02465 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E K9N68_26180 DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E K9N68_26975 recA; recombinase RecA K03553 recA; recombination protein RecA
E K9N68_28130 DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF
E K9N68_17640 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E K9N68_02435 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E K9N68_19740 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E K9N68_27970 recR; recombination mediator RecR K06187 recR; recombination protein RecR
E K9N68_03165 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E K9N68_14670 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E K9N68_31505 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
D Other HR factor
E K9N68_36435 cas1d; type I-D CRISPR-associated endonuclease Cas1d K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E K9N68_02465 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E K9N68_26180 DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
E K9N68_25975 DUF853 domain-containing protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F K9N68_04435 DNA topoisomerase 4 subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F K9N68_25750 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F K9N68_17210 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F K9N68_18440 DNA topoisomerase IB K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F K9N68_34590 topA; type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F K9N68_03015 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F K9N68_37740 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F K9N68_39165 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F K9N68_39860 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F K9N68_00695 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F K9N68_02435 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F K9N68_19740 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F K9N68_27970 recR; recombination mediator RecR K06187 recR; recombination protein RecR
E Facilitator
E Supressor
F K9N68_22480 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F K9N68_30580 ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F K9N68_00355 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F K9N68_33305 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D K9N68_21415 umuD; translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D K9N68_26975 recA; recombinase RecA K03553 recA; recombination protein RecA
D K9N68_11450 lexA; transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D K9N68_28355 lexA; transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D K9N68_32150 lexA; transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D K9N68_37460 hypothetical protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D K9N68_03165 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D K9N68_06055 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D K9N68_28010 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D K9N68_37355 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D K9N68_19380 ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D K9N68_03900 hypothetical protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D K9N68_30600 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D K9N68_30475 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D K9N68_27990 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024