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Transfer RNA Biogenesis - Klebsiella variicola 342
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D KPK_1484 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D KPK_0660 cca; multifunctional CCA protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D KPK_1389 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D KPK_4526 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D KPK_4735 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D KPK_3899 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D KPK_1608 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D KPK_3872 glnS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D KPK_1896 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D KPK_0780 lysS; lysyl-tRNA synthetase LysS K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D KPK_4090 lysyl-tRNA synthetase LysS homolog K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D KPK_1904 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D KPK_1098 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D KPK_1795 threonyl and alanyl tRNA synthetase domain protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D KPK_4722 threonyl and alanyl tRNA synthetase domain protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D KPK_3602 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D KPK_2138 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D KPK_3635 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D KPK_4197 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D KPK_5005 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D KPK_1276 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D KPK_2142 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D KPK_2143 pheT; phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D KPK_2373 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D KPK_0361 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D KPK_4890 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D KPK_5500 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D KPK_3456 hinT; purine nucleoside phosphoramidase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D KPK_0717 trmB; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D KPK_4525 conserved hypothetical protein TIGR00104 K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D KPK_1436 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D KPK_0548 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D KPK_1016 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D KPK_1257 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D KPK_1705 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D KPK_0433 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D KPK_5099 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D KPK_5564 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D KPK_5535 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D KPK_3237 selD; selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D KPK_5060 cysQ; 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D KPK_5566 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D KPK_1484 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D KPK_2357 rnt; ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D KPK_0110 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D KPK_3920 rna; ribonuclease I K01169 rna; ribonuclease I (enterobacter ribonuclease) [EC:4.6.1.21]
D KPK_3151 rnb; exoribonuclease II K01147 rnb; exoribonuclease II [EC:3.1.13.1]
D KPK_1972 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
C CCA adding factors
D KPK_0660 cca; multifunctional CCA protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
C Other tRNA splicing factors
D KPK_4589 ligT; 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
B tRNA transport factors
C tRNA export factors
D KPK_4768 ABC transporter, ATP-binding protein K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D KPK_3899 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D KPK_4526 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D KPK_2373 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D KPK_0361 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D KPK_4890 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D KPK_2138 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D KPK_4735 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D KPK_0780 lysS; lysyl-tRNA synthetase LysS K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D KPK_4090 lysyl-tRNA synthetase LysS homolog K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D KPK_1098 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D KPK_1795 threonyl and alanyl tRNA synthetase domain protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D KPK_4722 threonyl and alanyl tRNA synthetase domain protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D KPK_5005 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D KPK_1608 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D KPK_3635 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D KPK_1904 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D KPK_0182 glyQ; glycyl-tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D KPK_0183 glyS; glycyl-tRNA synthetase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D KPK_4197 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D KPK_1389 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D KPK_3872 glnS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D KPK_1896 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D KPK_2142 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D KPK_2143 pheT; phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D KPK_1276 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D KPK_3602 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D KPK_4592 gluQ; glutamyl-Q tRNA(Asp) synthetase K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D KPK_5500 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D KPK_4218 ybaK; ybaK/ebsC protein K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D KPK_3305 YbaK/prolyl-tRNA synthetase-associated domain protein K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D KPK_1239 tadA; tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
D KPK_5239 dusA; tRNA-dihydrouridine synthase A K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D KPK_0448 dusB; tRNA-dihydrouridine synthase B K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D KPK_1587 dusC; tRNA-dihydrouridine synthase C K05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]
C Methylthiotransferases
D KPK_3887 miaB; tRNA-i(6)A37 thiotransferase enzyme MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D KPK_1900 putative methyltransferase K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D KPK_1899 putative methyltransferase K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D KPK_3611 smtA; SmtA protein K06219 smtA; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]
D KPK_4757 RNA methyltransferase, TrmH family, group 1 K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D KPK_5427 trmA; tRNA (uracil-5-)-methyltransferase K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D KPK_0717 trmB; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D KPK_1190 trmD; tRNA (guanine-N1)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D KPK_5564 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D KPK_1217 RNA methyltransferase, TrmH family K03214 yfiF; RNA methyltransferase, TrmH family [EC:2.1.1.-]
D KPK_0097 trmH; tRNA guanosine-2'-O-methyltransferase K00556 trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34]
D KPK_1255 RNA methyltransferase, TrmH family, group 1 K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D KPK_0145 RNA methyltransferase, TrmH family, group 2 K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D KPK_4525 conserved hypothetical protein TIGR00104 K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D KPK_1222 putative methyltransferase K15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223]
C Psudouridine synthases
D KPK_1436 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D KPK_0548 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D KPK_0988 truC; tRNA pseudouridine synthase C K06175 truC; tRNA pseudouridine65 synthase [EC:5.4.99.26]
D KPK_1016 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D KPK_2031 pseudouridine synthase, RluA family K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
D KPK_4685 pseudouridine synthase, RluA family K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D KPK_3410 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D KPK_3031 PP-loop family protein K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D KPK_0277 tusA; sulfurtransferase TusA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D KPK_0389 tusB; protein TusB K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D KPK_0388 tusC; sulfur relay protein TusC/DsrF K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D KPK_0387 tusD; sulfurtransferase TusD K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D KPK_3570 tusE; sulfurtransferase TusE K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D KPK_1259 iscA; iron-sulfur cluster assembly protein IscA K13628 iscA; iron-sulfur cluster assembly protein
D KPK_1257 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D KPK_1705 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D KPK_0772 ygfZ; tRNA-modifying protein YgfZ K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D KPK_5535 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D KPK_5099 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D KPK_5007 miaE; tRNA-(MS[2]IO[6]A)-hydroxylase K06169 miaE; tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase [EC:1.14.99.69]
D KPK_1425 mnmC; tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D KPK_4328 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D KPK_4276 queC; queuosine biosynthesis protein QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D KPK_1003 queD; queuosine biosynthesis protein QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D KPK_1002 radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D KPK_0985 queF; 7-cyano-7-deazaguanine reductase K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D KPK_5104 iron-sulfur cluster binding protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D KPK_3237 selD; selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D KPK_4203 selU; tRNA 2-selenouridine synthase K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D KPK_4327 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D KPK_4309 thiI; thiamine biosynthesis/tRNA modification protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D KPK_4532 tilS; tRNA(Ile)-lysidine synthase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D KPK_1328 conserved hypothetical protein K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D KPK_1969 glycoprotease family protein K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D KPK_0433 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D KPK_0647 gcp; O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D KPK_5102 conserved hypothetical protein TIGR00150 K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D KPK_0954 ThiF family protein K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C KPK_5089 rnr; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C KPK_0551 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C KPK_A0156 vagD; vagD protein K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024