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Transfer RNA Biogenesis - Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52)
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D KPN_02665 elaC; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D KPN_03460 cca; tRNA nucleotidyl transferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D KPN_02750 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D KPN_00208 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D KPN_00021 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D KPN_00674 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D KPN_02560 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D KPN_00701 glnS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D KPN_02388 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D KPN_00502 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D KPN_03318 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D KPN_02380 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D KPN_03029 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D KPN_00961 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D KPN_02180 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D KPN_00925 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D KPN_00482 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D KPN_04663 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D KPN_02844 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D KPN_02176 pheS; phenylalanyl-tRNA synthetase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D KPN_02175 pheT; phenylalanyl-tRNA synthetase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D KPN_01975 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D KPN_04752 trpS; putative tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D KPN_03755 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D KPN_04182 dtd; D-tyrosyl-tRNA deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D KPN_01100 ycfF; hypothetical protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D KPN_03392 yggH; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D KPN_00209 yaeB; hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D KPN_02708 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D KPN_03574 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D KPN_03107 ygbO; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D KPN_02862 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D KPN_03683 yrdC; putative RNA-binding protein with unique protein fold K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D KPN_04569 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D KPN_04110 trmE; tRNA modification GTPase K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D KPN_04146 gidA; glucose-inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D KPN_01207 selD; selenophosphate synthetase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D KPN_04608 cysQ; hypothetical protein K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D KPN_02665 elaC; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D KPN_01991 rnt; ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D KPN_03984 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D KPN_01282 rnb; exoribonuclease II K01147 rnb; exoribonuclease II [EC:3.1.13.1]
D KPN_02321 rnd; RNase D, processes tRNA precursor K03684 rnd; ribonuclease D [EC:3.1.13.5]
C CCA adding factors
D KPN_03460 cca; tRNA nucleotidyl transferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
C Other tRNA splicing factors
D KPN_00147 ligT; 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
B tRNA transport factors
C tRNA export factors
D KPN_04846 yjjK; putative ATP-binding component of a transport system K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D KPN_00674 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D KPN_00208 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D KPN_01975 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D KPN_04752 trpS; putative tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D KPN_03755 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D KPN_02180 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D KPN_00021 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D KPN_00502 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D KPN_03318 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D KPN_03029 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D KPN_04663 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D KPN_02560 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D KPN_00925 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D KPN_02380 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D KPN_03923 glyQ; glycyl-tRNA synthetase alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D KPN_03922 glyS; glycyl-tRNA synthetase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D KPN_00482 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D KPN_02750 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D KPN_00701 glnS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D KPN_02388 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D KPN_02176 pheS; phenylalanyl-tRNA synthetase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D KPN_02175 pheT; phenylalanyl-tRNA synthetase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D KPN_02844 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D KPN_00961 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D KPN_00144 yadB; glutamyl-tRNA synthetase K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D KPN_04182 dtd; D-tyrosyl-tRNA deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D KPN_00462 ybaK; hypothetical protein K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D KPN_01179 yeaK; hypothetical protein K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D KPN_02884 tadA; tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
D KPN_04436 yjbN; conserved protein, FMN-linked K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D KPN_03669 yhdG; conserved protein, FMN-linked K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D KPN_02581 yohI; conserved protein, FMN-linked K05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]
C Methylthiotransferases
D KPN_00686 yleA; hypothetical protein K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D KPN_02384 yecO; putative methyltransferase K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D KPN_02385 yecP; putative methyltransferase K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D KPN_00948 smtA; S-adenosylmethionine-dependent methyltransferase K06219 smtA; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]
D KPN_04857 lasT; putative tRNA/rRNA methyltransferase K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D KPN_04254 trmA; tRNA (uracil-5-)-methyltransferase K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D KPN_03392 yggH; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D KPN_02930 trmD; tRNA (guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D KPN_04110 trmE; tRNA modification GTPase K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D KPN_02904 yfiF; putative tRNA/rRNA methyltransferase K03214 yfiF; RNA methyltransferase, TrmH family [EC:2.1.1.-]
D KPN_03999 trmH; putative tRNA/rRNA methyltransferase K00556 trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34]
D KPN_02864 yfhQ; hypothetical tRNA/rRNA methyltransferase K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D KPN_03950 yibK; putative tRNA/rRNA methyltransferase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D KPN_00209 yaeB; hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D KPN_02900 yfiC; putative enzyme K15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223]
C Psudouridine synthases
D KPN_02708 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D KPN_03574 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D KPN_03134 yqcB; pseudouridine synthase K06175 truC; tRNA pseudouridine65 synthase [EC:5.4.99.26]
D KPN_03107 ygbO; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D KPN_00057 rluA; 23S rRNA pseudouridylate 746 synthase K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
D KPN_02278 putative ribosomal large subunit pseudouridine synthase A K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D KPN_01141 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D KPN_01375 ydaO; hypothetical protein K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D KPN_03836 sirA; hypothetical protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D KPN_03728 yheL; hypothetical protein K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D KPN_03729 yheM; hypothetical protein K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D KPN_03730 yheN; hypothetical protein K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D KPN_01005 yccK; putative sulfite reductase, gamma subunit K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D KPN_02860 iscA; iron-sulfur cluster assembly protein K13628 iscA; iron-sulfur cluster assembly protein
D KPN_02862 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D KPN_03326 ygfZ; putative enzyme K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D KPN_04146 gidA; glucose-inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D KPN_04569 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D KPN_04661 miaE; hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA K06169 miaE; tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase [EC:1.14.99.69]
D KPN_02714 yfcK; hypothetical protein K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D KPN_00356 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D KPN_00406 ybaX; putative (aluminum) resistance protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D KPN_03120 ygcM; putative 6-pyruvoyl tetrahydrobiopterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D KPN_03121 ygcF; putative coenzyme PQQ synthesis protein, nitrogenase iron-molybdenum domain K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D KPN_03137 yqcD; hypothetical protein K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D KPN_04564 yjeS; conserved ferredoxin-like protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D KPN_01207 selD; selenophosphate synthetase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D KPN_00476 ybbB; putative capsule anchoring protein K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D KPN_00357 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D KPN_00375 thiI; thiamine biosynthesis protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D KPN_00201 tilS; tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D KPN_02808 ypfI; putative acyl-CoA N-acyltransferase K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D KPN_02324 yeaZ; putative glycoprotein endopeptidase K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D KPN_03683 yrdC; putative RNA-binding protein with unique protein fold K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D KPN_03471 ygjD; putative O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D KPN_04566 yjeE; putative enzyme K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D KPN_03163 ygdL; putative enzyme K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C KPN_04578 rnr; RNase R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C KPN_03572 pnp; polynucleotide phosphorylase, has polyadenylase activity K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C KPN_pKPN4p07073 mck; putative DNA binding protein K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024