+F Repair protein KO #

  DNA Repair and Recombination Proteins - Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52)

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D KPN_01531 ogt; O-6-alkylguanine-DNA/cysteine-protein methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D KPN_00719 phrB; deoxyribodipyrimidine photolyase (photoreactivation) K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E KPN_02903 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E KPN_03393 mutY; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E KPN_01970 nth; endonuclease III; DNA glycosylase/apyrimidinic (AP) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex E DNA polymerase epsilon complex D Short Patch-BER factors D Other BER factors C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex E Cul4-CSA complex E Other TCR factor D TFIIH complex D RPA (replication factor A) D Other NER factors C MMR (mismatch excision repair) D Mismatch and loop recognition factors D MutL homologs D DNA polymerase delta complex D RPA (replication factor A) D RFC (replication factor C) D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex D BRCA complex D RecA family proteins D Rad52 family proteins D Rad54 family proteins D RecQ family DNA helicases D Bloom's syndrome complex (BTR) D RPA (replication factor A) D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex D Other HR factors C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) D FANCD2-I complex D Downstream FA components D Other FA pathway factors C Other DSBR factors D Protein phosphatase 6 D Ubiquitin ligases D Others B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group C Other TLS factors B Check point factors C Rad9-Hus1-Rad1 complex C HRAD17(Rad24)-RFC complex C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex C SOSS complex C Other check point factors B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex C Modulation of nucleotide pools D KPN_00103 mutT; 7,8-dihydro-8-oxoguanine-triphosphatase, prefers dGTP K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D KPN_03980 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D KPN_01531 ogt; O-6-alkylguanine-DNA/cysteine-protein methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D KPN_02634 ada; O6-methylguanine-DNA methyltransferase; transcription activator/repressor K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63] D KPN_03992 putative methylated-DNA-[protein]-cysteine S-methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63] D KPN_00719 phrB; deoxyribodipyrimidine photolyase (photoreactivation) K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D KPN_02633 alkB; DNA repair system specific for alkylated DNA K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33] C BER (base exicision repair) D DNA glycosylases E KPN_02903 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E KPN_03475 ygjF; DNA glycosylase, G/U mismatch-specific K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28] E KPN_02520 alkA; 3-methyl-adenine DNA glycosylase II, inducible K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21] E KPN_03393 mutY; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E KPN_03907 tag; 3-methyl-adenine DNA glycosylase I, constitutive K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] E KPN_03975 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E KPN_00726 nei; endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E KPN_01970 nth; endonuclease III; DNA glycosylase/apyrimidinic (AP) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E KPN_01220 xthA; exonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2] E KPN_02597 nfo; endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] E KPN_04380 nfi; endonuclease V (deoxyinosine 3'endoduclease) K05982 nfi; deoxyribonuclease V [EC:3.1.21.7] D RecJ E KPN_03320 recJ; ssDNA exonuclease, 5' --> 3' specific K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D DNA ligase E KPN_02758 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E KPN_03995 yicF; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D DNA polymerase I E KPN_04172 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] C NER (nucleotide excision repair) D GGR (global genome repair) factors E KPN_04445 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A E KPN_00804 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B E KPN_02411 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C E KPN_01227 ydjQ; endonuclease in nucleotide excision repair K05984 cho; excinuclease Cho [EC:3.1.25.-] E KPN_04312 uvrD; DNA-dependent ATPase I and helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E KPN_04172 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] E KPN_02758 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E KPN_03995 yicF; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) F KPN_04365 rpoB; DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] F KPN_04366 rpoC; DNA-directed RNA polymerase beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] F KPN_03695 rpoA; DNA-directed RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] F KPN_03997 rpoZ; DNA-directed RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] E TRCF (transcription-repair coupling factor) F KPN_01112 mfd; transcription-repair ATP-dependent coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] C MMR (mismatch excision repair) D Mismatch and loop recognition factors E KPN_03094 mutS; DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS D Molecular matchmaker E KPN_04568 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL D Strand discrimination factor E KPN_03240 mutH; DNA mismatch repair protein K03573 mutH; DNA mismatch repair protein MutH D DNA exonucleases E KPN_02469 sbcB; 3' --> 5' specific exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1] E KPN_02835 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E KPN_00374 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] E KPN_02360 exoX; exodeoxyribonuclease X K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-] D DNA polymerase III holoenzyme E KPN_00197 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E KPN_04104 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E KPN_04664 holC; DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] E KPN_00672 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E KPN_01097 holB; DNA polymerase III subunit delta K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E KPN_00230 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E KPN_00452 dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] E KPN_04828 holD; DNA polymerase III subunit psi K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7] E KPN_02359 holE; DNA polymerase III, theta subunit K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7] E KPN_pKPN3p05978 putative inner membrane protein K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7] E KPN_pKPN4p07104 hypothetical protein K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7] E KPN_pKPN5p08168 hypothetical protein K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7] D DNA ligase E KPN_02758 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E KPN_03995 yicF; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Other MMR factors E KPN_04312 uvrD; DNA-dependent ATPase I and helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E KPN_04446 ssb; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein E KPN_pKPN3p05983 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein E KPN_pKPN4p07109 ssb; single-stranded binding protein K03111 ssb; single-strand DNA-binding protein E KPN_03758 dam; DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] E KPN_02427 vsr; DNA mismatch endonuclease, patch repair protein K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-] B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins E KPN_03229 recB; DNA helicase, ATP-dependent dsDNA/ssDNA exonuclease V subunit, ssDNA endonuclease K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5] E KPN_03231 recC; DNA helicase, ATP-dependent dsDNA/ssDNA exonuclease V subunit, ssDNA endonuclease K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5] E KPN_03228 recD; DNA helicase, ATP-dependent dsDNA/ssDNA exonuclease V subunit, ssDNA endonuclease K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] E KPN_03031 recA; recombinase A K03553 recA; recombination protein RecA E KPN_02376 ruvA; Holliday junction DNA helicase motor protein K03550 ruvA; holliday junction DNA helicase RuvA E KPN_02375 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E KPN_02377 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] E KPN_04230 priA; primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] E KPN_04595 priB; primosomal replication protein N K02686 priB; primosomal replication protein N E KPN_00449 priC; primosomal replication protein N'' K04067 priC; primosomal replication protein N'' E KPN_04812 dnaT; primosomal protein I K02317 dnaT; DNA replication protein DnaT E KPN_02469 sbcB; 3' --> 5' specific exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1] E KPN_00338 sbcC; ATP-dependent dsDNA exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50 E KPN_00339 sbcD; ATP-dependent dsDNA exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11 D RecFOR pathway proteins E KPN_03031 recA; recombinase A K03553 recA; recombination protein RecA E KPN_04844 sms; probable ATP-dependent protease K04485 radA; DNA repair protein RadA/Sms E KPN_04103 recF; recombination protein F K03629 recF; DNA replication and repair protein RecF E KPN_04000 recG; DNA helicase, ATP-dependent resolution of Holliday junctions, branch migration K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E KPN_03320 recJ; ssDNA exonuclease, 5' --> 3' specific K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] E KPN_02890 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) E KPN_00454 recR; recombination protein RecR K06187 recR; recombination protein RecR E KPN_02938 recN; protein used in recombination and DNA repair K03631 recN; DNA repair protein RecN (Recombination protein N) E KPN_00336 rdgC; recombination associated protein K03554 rdgC; recombination associated protein RdgC E KPN_02376 ruvA; Holliday junction DNA helicase motor protein K03550 ruvA; holliday junction DNA helicase RuvA E KPN_02375 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E KPN_02377 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D AddAB pathway proteins D Other HR factor E KPN_02617 yejH; putative ATP-dependent helicase K19789 radD; DNA repair protein RadD D Archaeal homologous recombinant proteins E KPN_00338 sbcC; ATP-dependent dsDNA exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50 E KPN_00339 sbcD; ATP-dependent dsDNA exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11 E KPN_04668 yjgR; putative enzyme contains P-loop containing nucleotide triphosphate hydrolase domain K06915 herA; DNA double-strand break repair helicase HerA and related ATPase C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F KPN_02640 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F KPN_04102 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F KPN_01270 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] E Supressor F KPN_04382 hupA; DNA-binding protein HU-alpha (HU-2) K05787 hupA; DNA-binding protein HU-alpha F KPN_00402 hupB; DNA-binding protein HU-beta, NS1 (HU-1) K03530 hupB; DNA-binding protein HU-beta D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway F KPN_01383 putative enterobacterial exodeoxyribonuclease VIII K10906 recE; exodeoxyribonuclease VIII [EC:3.1.11.-] F KPN_03320 recJ; ssDNA exonuclease, 5' --> 3' specific K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] F KPN_02890 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) F KPN_00454 recR; recombination protein RecR K06187 recR; recombination protein RecR F KPN_02758 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] F KPN_03995 yicF; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E Facilitator F KPN_03670 fis; DNA-binding protein Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein F KPN_02174 himA; integration host factor alpha subunit K04764 ihfA; integration host factor subunit alpha F KPN_00939 himD; integration host factor beta subunit K05788 ihfB; integration host factor subunit beta E Supressor F KPN_02469 sbcB; 3' --> 5' specific exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1] F KPN_04317 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] F KPN_04445 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A F KPN_00804 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B F KPN_02201 hns; DNA-binding protein HLP-II (HU, BH2, HD, NS); pleiotropic regulator K03746 hns; DNA-binding protein H-NS B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D KPN_00247 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D KPN_01184 putative UMUC-like DNA-repair protein K03502 umuC; DNA polymerase V D KPN_01439 umuC; DNA polymerase IV K03502 umuC; DNA polymerase V D KPN_pKPN3p05973 umuDC operon protein-like protein K03502 umuC; DNA polymerase V D KPN_pKPN5p08225 mutagenesis by UV and mutagens K03502 umuC; DNA polymerase V D KPN_01183 SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC K03503 umuD; DNA polymerase V [EC:3.4.21.-] D KPN_01438 umuD; SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC K03503 umuD; DNA polymerase V [EC:3.4.21.-] D KPN_pKPN3p05974 umuDC operon protein-like protein K03503 umuD; DNA polymerase V [EC:3.4.21.-] D KPN_pKPN4p07093 putative ImpA protein K03503 umuD; DNA polymerase V [EC:3.4.21.-] D KPN_pKPN5p08226 impA; ImpA-like protein; UV protection K03503 umuD; DNA polymerase V [EC:3.4.21.-] C Other SOS response factors D KPN_03031 recA; recombinase A K03553 recA; recombination protein RecA D KPN_04431 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88] D KPN_02938 recN; protein used in recombination and DNA repair K03631 recN; DNA repair protein RecN (Recombination protein N) D KPN_00059 polB; DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7] D KPN_04446 ssb; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein D KPN_pKPN3p05983 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein D KPN_pKPN4p07109 ssb; single-stranded binding protein K03111 ssb; single-strand DNA-binding protein D KPN_04089 putative DNA-damage-inducible protein K14623 dinD; DNA-damage-inducible protein D D KPN_01073 dinI; DNA damage-inducible protein I, inhibits UmuD processing K12149 dinI; DNA-damage-inducible protein I D KPN_03030 recX; RecA regulator RecX K03565 recX; regulatory protein D KPN_04771 putative transposase K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-] B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases D KPN_04276 rep; Rep helicase, a single-stranded DNA-dependent ATPase K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4] D KPN_00991 helD; DNA helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4] D KPN_00831 dinG; LexA-regulated (SOS) repair enzyme K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D KPN_02325 yoaA; putative ATP-dependent helicase, SOS repair K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D KPN_pKPN3p05866 hypothetical ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] C Modulation of nucleotide pools D KPN_00103 mutT; 7,8-dihydro-8-oxoguanine-triphosphatase, prefers dGTP K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D KPN_03980 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D KPN_02642 nrdA; ribonucleotide-diphosphate reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D KPN_03006 nrdE; ribonucleotide-diphosphate reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D KPN_02643 nrdB; ribonucleotide-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D KPN_03007 nrdF; ribonucleotide-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C Others ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 23, 2026