+F Repair protein KO
#
DNA Repair and Recombination Proteins - Klebsiella pneumoniae subsp. rhinoscleromatis SB3432
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D KPR_2812 ogt; highly similar to methylated-DNA--protein-cysteine methyltransferase from Salmonella typhimurium (sp|P0A2U0) K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E KPR_1370 ung; highly similar to uracil-DNA glycosylase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCJ2) K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E KPR_4664 mutY; highly similar to A/G-specific adenine glycosylase from Escherichia coli O44:H18 strain 042 - EAEC (tr|D3GUM5) K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E KPR_3008 nth; highly similar to endonuclease III from Escherichia coli strain K12 (sp|P0AB83) K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D KPR_1031 mutT; highly similar to 7,8-dihydro-8-oxoguanine-triphosphatase from Escherichia coli strain SMS-3-5 - SECEC (tr|B1LG36) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D KPR_4933 dut; highly similar to deoxyuridine 5'-triphosphate nucleotidohydrolase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TFN1) K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D KPR_2812 ogt; highly similar to methylated-DNA--protein-cysteine methyltransferase from Salmonella typhimurium (sp|P0A2U0) K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D KPR_2079 ada; highly similar to regulatory protein of adaptative response Ada from Escherichia coli strain K12 (sp|P06134) K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D KPR_0366 unnamed protein product; highly similar to N-terminal region of DNA-O6-methylguanine--protein-cysteine S-methyltransferase from Enterobacter sp. (tr|A4W4V5) K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D KPR_2080 alkB; highly similar to alpha-ketoglutarate-dependent dioxygenase AlkB from Escherichia coli strain K12 (sp|P05050) K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E KPR_1370 ung; highly similar to uracil-DNA glycosylase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCJ2) K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E KPR_4510 mug; highly similar to G/U mismatch-specific DNA glycosylase from Klebsiella pneumoniae strain 342 (sp|B5XU18) K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E KPR_1577 alkA; DNA-3-methyladenine glycosylase 2 K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E KPR_4664 mutY; highly similar to A/G-specific adenine glycosylase from Escherichia coli O44:H18 strain 042 - EAEC (tr|D3GUM5) K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E KPR_5008 unnamed protein product; similar to putative DNA-3-methyladenine glycosylase I from Escherichia coli strain UTI89 - UPEC (tr|Q1R547) K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E KPR_4938 mutM; highly similar to formamidopyrimidine-DNA glycosylase from Klebsiella pneumoniae strain 342 (sp|B5XTG8) K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E KPR_3852 end8; highly similar to endonuclease 8 from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T6E8) K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E KPR_3008 nth; highly similar to endonuclease III from Escherichia coli strain K12 (sp|P0AB83) K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E KPR_2265 xthA; highly similar to exodeoxyribonuclease II from Escherichia coli strain UTI89 - UPEC (tr|Q1RB43) K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E KPR_1495 nfo; highly similar to probable endonuclease 4 from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TBP4) K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E KPR_0318 nfi; highly similar to endonuclease V from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TGQ5) K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E KPR_4587 recJ; highly similar to single-stranded-DNA-specific exonuclease RecJ from Escherichia coli O6 (tr|Q8FE73) K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E KPR_1952 ligA; highly similar to DNA ligase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TC47) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E KPR_0362 ligB; highly similar to DNA ligase B from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TFP6) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E KPR_0132 polA; highly similar to DNA polymerase I from Enterobacter sp. strain 638 (tr|A4WGC6) K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E KPR_0427 uvrA; highly similar to Excinuclease ABC subunit A from Salmonella typhimurium (sp|P0A1950) K03701 uvrA; excinuclease ABC subunit A
E KPR_3783 uvrB; highly similar to UvrABC system protein B from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T6L9) K03702 uvrB; excinuclease ABC subunit B
E KPR_2275 cho; highly similar to excinuclease cho from Escherichia coli O157:H7 (sp|Q8XDZ7) K05984 cho; excinuclease Cho [EC:3.1.25.-]
E KPR_0262 uvrD; highly similar to DNA helicase II from Escherichia coli strain K12 (sp|P03018) K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E KPR_0132 polA; highly similar to DNA polymerase I from Enterobacter sp. strain 638 (tr|A4WGC6) K02335 polA; DNA polymerase I [EC:2.7.7.7]
E KPR_1952 ligA; highly similar to DNA ligase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TC47) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E KPR_0362 ligB; highly similar to DNA ligase B from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TFP6) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F KPR_0300 rpoB; highly similar to DNA-directed RNA polymerase subunit beta from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TGP0) K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F KPR_0301 rpoC; highly similar to DNA-directed RNA polymerase subunit beta' from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TGP1) K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F KPR_0776 rpoA; highly similar to DNA-directed RNA polymerase subunit alpha Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TEU8) K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F KPR_0360 rpoZ; highly similar to DNA-directed RNA polymerase subunit omega from Escherichia coli O150:H5 strain SE15 (tr|D2NCQ0) K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F KPR_2153 mfd; highly similar to transcription-repair coupling factor from Escherichia coli O55:H7 strain CB9615 - EPEC (tr|D3QQA9) K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E KPR_4089 mutS; highly similar to DNA mismatch repair protein MutS from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TD24) K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E KPR_0544 mutL; highly similar to DNA mismatch repair protein MutL from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TH85) K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E KPR_1793 mutH; highly similar to DNA mismatch repair protein MutH from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TDG7) K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E KPR_1633 sbcB; highly similar to exodeoxyribonuclease I from Escherichia coli strain K12 (sp|P04995) K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E KPR_1440 xseA; highly similar to exodeoxyribonuclease 7 large subunit from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCC4) K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E KPR_4347 xseB; highly similar to exodeoxyribonuclease 7 small subunit from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T5F5) K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E KPR_3271 exoX; highly similar to exodeoxyribonuclease 10 from Escherichia coli strain K12 (sp|P0AEK0) K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D DNA polymerase III holoenzyme
E KPR_1128 dnaE; highly similar to DNA polymerase III subunit alpha from Escherichia coli O6 (sp|Q8FL05) K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E KPR_0002 dnaN; highly similar to DNA polymerase III subunit beta from Salmonella typhimurium (sp|P26464) K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E KPR_0641 holC; highly similar to putative DNA polymerase III subunit chi from Salmonella paratyphi C (tr|C0Q7D5) K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E KPR_3903 holA; highly similar to DNA polymerase III subunit delta from Escherichia coli strain K12 (sp|P28630) K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E KPR_2137 holB; highly similar to DNA polymerase III, delta prime subunit from Escherichia coli O103:H2 strain 12009 - EHEC (tr|C8U5Q4) K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E KPR_1157 dnaQ; highly similar to DNA polymerase III, epsilon chain from Escherichia coli O6 (tr|Q8FKY4) K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E KPR_4206 dnaX; highly similar to DNA polymerase III subunit tau from Salmonella typhimurium (sp|P74876) K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E KPR_0906 holD; highly similar to DNA polymerase III, psi subunit from Escherichia coli strain SMS-3-5 - SECEC (tr|B1LEH5) K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
E KPR_p0107 unnamed protein product; highly similar to Hot from Salmonella enterica (tr|B5MTX3) K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
E KPR_3270 holE; highly similar to DNA polymerase III theta subunit from Escherichia coli strain UTI89 - UPEC (tr|Q1RAU4) K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
D DNA ligase
E KPR_1952 ligA; highly similar to DNA ligase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TC47) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E KPR_0362 ligB; highly similar to DNA ligase B from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TFP6) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E KPR_0262 uvrD; highly similar to DNA helicase II from Escherichia coli strain K12 (sp|P03018) K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E KPR_0428 ssb; highly similar to single-stranded DNA-binding protein from Escherichia coli strain UTI89 - UPEC (tr|Q1R3L1) K03111 ssb; single-strand DNA-binding protein
E KPR_p0105 unnamed protein product; similar to single-strand binding family protein from Escherichia coli MS 124-1 (tr|E1J7P1) K03111 ssb; single-strand DNA-binding protein
E KPR_2094 unnamed protein product; similar to putative single stranded DNA-binding protein of prophage from Escherichia coli O7:K1 strain IAI39 - ExPEC (tr|B7NKD9) K03111 ssb; single-strand DNA-binding protein
E KPR_0712 unnamed protein product; highly similar to DNA adenine methylase from from Escherichia coli strain K12 (sp|P0AEE8) K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E KPR_4676 unnamed protein product; highly similar to retron EC67 DNA adenine methylase from Escherichia coli (sp|P21311) K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E KPR_3378 vsr; highly similar to very short patch repair protein from Escherichia coli strain K12 (sp|P09184) K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E KPR_1804 recB; highly similar to exonuclease V (RecBCD complex), beta subunit from Escherichia coli O81 strain ED1a (tr|B7MYX4) K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E KPR_1802 recC; highly similar to exodeoxyribonuclease V gamma chain from Escherichia coli strain K12 (sp|P07648) K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E KPR_1805 recD; highly similar to exodeoxyribonuclease V alpha chain from Escherichia coli O6 (tr|Q8FEB4) K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E KPR_1259 recA; highly similar to protein RecA recombinase A from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCW1) K03553 recA; recombination protein RecA
E KPR_3289 ruvA; highly similar to holliday junction ATP-dependent DNA helicase RuvA from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TB31) K03550 ruvA; holliday junction DNA helicase RuvA
E KPR_3288 ruvB; highly similar to holliday junction ATP-dependent DNA helicase RuvB from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TB30) K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E KPR_3290 ruvC; highly similar to crossover junction endodeoxyribonuclease RuvC from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TB32) K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E KPR_0189 priA; highly similar to primosomal protein N' from Escherichia coli O55:H7 strain CB9615 - EPEC (tr|D3QYD5) K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E KPR_0571 priB; highly similar to putative primosomal protein N from Escherichia coli O111:H-strain 11128 - EHEC (tr|C8ULY6) K02686 priB; primosomal replication protein N
E KPR_4203 priC; similar to primosomal replication protein N from Escherichia coli strain SMS-3-5 - SECEC (tr|B1LJM4) K04067 priC; primosomal replication protein N''
E KPR_1453 unnamed protein product; weakly similar to C-terminal region of putative uncharacterized protein from Escherichia coli O18:K1:H7 strain IHE3034 - ExPEC (tr|D5CXJ3) K02317 dnaT; DNA replication protein DnaT
E KPR_0893 dnaT; highly similar to primosomal protein 1 from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6THX4) K02317 dnaT; DNA replication protein DnaT
E KPR_1633 sbcB; highly similar to exodeoxyribonuclease I from Escherichia coli strain K12 (sp|P04995) K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E KPR_4386 sbcC; similar to ATP-dependent dsDNA exonuclease SbcC from Escherichia coli O103:H2 strain 12009 - EHEC (tr|C8U281) K03546 sbcC; DNA repair protein SbcC/Rad50
E KPR_4385 sbcD; highly similar to exonuclease SbcD from Escherichia coli B088 (tr|D6HSS5) K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E KPR_1259 recA; highly similar to protein RecA recombinase A from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCW1) K03553 recA; recombination protein RecA
E KPR_0922 radA; highly similar to DNA repair protein RadA from Escherichia coli strain K12 (sp|P24554) K04485 radA; DNA repair protein RadA/Sms
E KPR_0003 recF; highly similar to DNA replication and repair protein RecF from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TG02) K03629 recF; DNA replication and repair protein RecF
E KPR_0357 recG; highly similar to ATP-dependent DNA helicase RecG from Escherichia coli strain UTI89 - UPEC (tr|Q1R4T9) K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E KPR_4587 recJ; highly similar to single-stranded-DNA-specific exonuclease RecJ from Escherichia coli O6 (tr|Q8FE73) K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E KPR_1383 recO; highly similar to DNA repair protein RecO from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCH9) K03584 recO; DNA repair protein RecO (recombination protein O)
E KPR_4208 recR; highly similar to recombination protein RecR from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T5N5) K06187 recR; recombination protein RecR
E KPR_1335 recN; highly similar to DNA repair protein from Escherichia coli O44:H18 strain 042 - EAEC (tr|D3H4M9) K03631 recN; DNA repair protein RecN (Recombination protein N)
E KPR_4388 rdgC; highly similar to recombination-associated protein RdgC from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 9sp|A6T5B7) K03554 rdgC; recombination associated protein RdgC
E KPR_3289 ruvA; highly similar to holliday junction ATP-dependent DNA helicase RuvA from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TB31) K03550 ruvA; holliday junction DNA helicase RuvA
E KPR_3288 ruvB; highly similar to holliday junction ATP-dependent DNA helicase RuvB from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TB30) K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E KPR_3290 ruvC; highly similar to crossover junction endodeoxyribonuclease RuvC from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TB32) K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E KPR_4118 unnamed protein product; highly similar to CRISPR-associated protein Cas1 from Escherichia coli O139:H28 strain E24377A - ETEC (tr|A7ZQJ8) K15342 cas1; CRISP-associated protein Cas1
E KPR_1473 yejH; highly similar to predicted ATP-dependent helicase from Escherichia coli O111:H-strain 11128 - EHEC (tr|C8UDB4) K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E KPR_4386 sbcC; similar to ATP-dependent dsDNA exonuclease SbcC from Escherichia coli O103:H2 strain 12009 - EHEC (tr|C8U281) K03546 sbcC; DNA repair protein SbcC/Rad50
E KPR_4385 sbcD; highly similar to exonuclease SbcD from Escherichia coli B088 (tr|D6HSS5) K03547 sbcD; DNA repair protein SbcD/Mre11
E KPR_0645 yjgR; highly similar to putative uncharacterized protein yjgR from Shigella sonnei (tr|Q3YU86) K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F KPR_2073 gyrA; highly similar to DNA gyrase subunit A from Salmonella typhimurium (sp|P37411) K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F KPR_0004 gyrB; highly similar to DNA gyrase subunit B from Escherichia coli O6 (tr|Q8FBV7) K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F KPR_2321 topA; highly similar to DNA topoisomerase 1 from Salmonella typhimurium (sp|P0A2I1) K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F KPR_4317 hupB; highly similar to DNA-binding protein HU-beta, NS1 (HU-1) from Escherichia coli strain UTI89 - UPEC (tr|Q1RF95) K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F KPR_1447 unnamed protein product; highly similar to recombination and repair protein RecT from Escherichia coli MS 185-1 (tr|D8CA84) K07455 recT; recombination protein RecT
F KPR_4587 recJ; highly similar to single-stranded-DNA-specific exonuclease RecJ from Escherichia coli O6 (tr|Q8FE73) K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F KPR_1383 recO; highly similar to DNA repair protein RecO from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCH9) K03584 recO; DNA repair protein RecO (recombination protein O)
F KPR_4208 recR; highly similar to recombination protein RecR from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T5N5) K06187 recR; recombination protein RecR
F KPR_1952 ligA; highly similar to DNA ligase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TC47) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F KPR_0362 ligB; highly similar to DNA ligase B from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TFP6) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F KPR_4856 fis; highly similar to global DNA-binding transcriptional dual regulator Fis from Escherichia coli O111:H-strain 11128 - EHEC (tr|C8UGL9) K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F KPR_2722 unnamed protein product; highly similar to integration host factor subunit alpha from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TAI1) K04764 ihfA; integration host factor subunit alpha
F KPR_3639 ihfB; highly similar to integration host factor subunit beta from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T704) K05788 ihfB; integration host factor subunit beta
E Supressor
F KPR_1633 sbcB; highly similar to exodeoxyribonuclease I from Escherichia coli strain K12 (sp|P04995) K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F KPR_0267 recQ; highly similar to putative ATP-dependent DNA helicase from Escherichia coli O157:H7 (tr|Q8X8N1) K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F KPR_0427 uvrA; highly similar to Excinuclease ABC subunit A from Salmonella typhimurium (sp|P0A1950) K03701 uvrA; excinuclease ABC subunit A
F KPR_3783 uvrB; highly similar to UvrABC system protein B from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T6L9) K03702 uvrB; excinuclease ABC subunit B
F KPR_3120 hns; highly similar to Hns transcriptional dual regulator from Escherichia coli strain UTI89 - UPEC (tr|Q1RCK0) K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D KPR_1174 dinB; highly similar to DNA polymerase IV from Shigella sonnei (sp|Q3Z5A4) K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D KPR_p0119 samB; highly similar to protein SamB from Salmonella typhimurium (sp|P23832) K03502 umuC; DNA polymerase V
D KPR_2229 umuC; highly similar to protein UmuC from Escherichia coli strain K12 (sp|P04152) K03502 umuC; DNA polymerase V
D KPR_5128 unnamed protein product; highly similar to C-terminal region of protein SamB from Escherichia fergusonii (tr|B7L3W9) K03502 umuC; DNA polymerase V
D KPR_5126 umuD; similar to UmuD protein from Escherichia coli O6 (tr|Q8FI26) K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D KPR_2228 umuD; highly similar to UmuD protein from Escherichia coli O6 (tr|Q8FI26) K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D KPR_p0118 unnamed protein product; similar to protein SamA from Salmonella typhimurium (sp|P23831) K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D KPR_1525 unnamed protein product; highly simialr to putative uncharacterized protein from Escherichia coli O9:H4 strain HS (tr|A7ZWR3) K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D KPR_1259 recA; highly similar to protein RecA recombinase A from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCW1) K03553 recA; recombination protein RecA
D KPR_0413 lexA; highly similar to LexA repressor from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TGV2) K01356 lexA; repressor LexA [EC:3.4.21.88]
D KPR_1335 recN; highly similar to DNA repair protein from Escherichia coli O44:H18 strain 042 - EAEC (tr|D3H4M9) K03631 recN; DNA repair protein RecN (Recombination protein N)
D KPR_0983 polB; highly similar to DNA polymerase from Escherichia coli O45:K1 strain S88 - ExPEC (tr|B7MAI3) K02336 polB; DNA polymerase II [EC:2.7.7.7]
D KPR_0428 ssb; highly similar to single-stranded DNA-binding protein from Escherichia coli strain UTI89 - UPEC (tr|Q1R3L1) K03111 ssb; single-strand DNA-binding protein
D KPR_p0105 unnamed protein product; similar to single-strand binding family protein from Escherichia coli MS 124-1 (tr|E1J7P1) K03111 ssb; single-strand DNA-binding protein
D KPR_2094 unnamed protein product; similar to putative single stranded DNA-binding protein of prophage from Escherichia coli O7:K1 strain IAI39 - ExPEC (tr|B7NKD9) K03111 ssb; single-strand DNA-binding protein
D KPR_2119 dinI; similar to DNA damage-inducible protein I from Escherichia coli O45:K1 strain S88 - ExPEC (tr|B7MIK2) K12149 dinI; DNA-damage-inducible protein I
D KPR_4548 unnamed protein product; highly similar to DinI-like protein in retron EC67 from Escherichia coli (sp|P21320) K12149 dinI; DNA-damage-inducible protein I
D KPR_p0117 unnamed protein product; highly similar to putative uncharacterized protein ImpC from Klebsiella pneumoniae subsp. rhinoscleromatis ATCC 13884 (tr|C8T454) K12149 dinI; DNA-damage-inducible protein I
D KPR_1330 unnamed protein product; highly similar to DinI-like protein Z3305/ECs2939 in prophage CP-933V from Escherichia coli O157:H7 (sp|Q9EYF1) K12149 dinI; DNA-damage-inducible protein I
D KPR_1260 recX; highly similar to regulatory protein RecX from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCW0) K03565 recX; regulatory protein
D KPR_p0041 ytl2; highly similar to uncharacterized protein pSLT051 from Salmonella typhimurium (sp|P37415) K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
D KPR_0846 yhgA; highly similar to putative transposase YhgA family protein fro Klebsiella variicola strain At-22 (tr|D3RDP6) K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
D KPR_4535 ytl2; highly similar to uncharacterized protein pSLT051 from Salmonella typhimurium (sp|P37415) K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D KPR_0230 rep; highly similar to ATP-dependent DNA helicase rep from Salmonella typhimurium (sp|Q9L6S1) K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D KPR_1675 helD; highly similar to helicase IV from Escherichia coli strain K12 (sp|P15038) K03658 helD; DNA helicase IV [EC:5.6.2.4]
D KPR_3237 yoaA; highly similar to probable ATP-dependent helicase YoaA from Escherichia coli O6:K15:H31 strain 536 - UPEC (tr|Q0TH25) K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D KPR_3757 dinG; highly similar to probable ATP-dependent helicase DinG from Escherichia coli O6 (sp|Q8FJN1) K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D KPR_1031 mutT; highly similar to 7,8-dihydro-8-oxoguanine-triphosphatase from Escherichia coli strain SMS-3-5 - SECEC (tr|B1LG36) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D KPR_4933 dut; highly similar to deoxyuridine 5'-triphosphate nucleotidohydrolase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TFN1) K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D KPR_2071 nrdA; highly similar to ribonucleoside-diphosphate reductase 1 subunit alpha from Salmonella typhimurium (sp|P37426) K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D KPR_1283 nrdE; highly similar to ribonucleoside-diphosphate reductase from Escherichia coli O150:H5 strain SE15 (tr|D2NLI8) K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D KPR_2070 nrdB; highly similar to ribonucleotide-diphosphate reductase beta subunit from Escherichia coli O1:K1 - APEC (tr|A1AD88) K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D KPR_1282 nrdF; highly similar to ribonucleoside-diphosphate reductase 2 subunit beta from Salmonella typhimurium (sp|P17424) K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024