+F Repair protein KO
#
DNA Repair and Recombination Proteins - Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D VK055_0973 methylated-DNA-[]-cysteine S-methyltransferase family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D VK055_1811 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E VK055_4598 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E VK055_4082 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E VK055_0508 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D VK055_2468 mutT; 8-oxo-dGTPase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D VK055_3489 dut; dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D VK055_0973 methylated-DNA-[]-cysteine S-methyltransferase family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D VK055_3476 methylated-DNA-cysteine S-methyltransferase family protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D VK055_4887 ada transcriptional dual regulator K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D VK055_1811 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D VK055_4888 alkB repair system for alkylated DNA and RNA K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E VK055_4598 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E VK055_3994 uracil DNA glycosylase superfamily protein K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E VK055_5007 3-methyl-adenine DNA glycosylase II, inducible K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E VK055_4082 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E VK055_3562 tag; 3-methyladenine DNA glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E VK055_3494 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E VK055_1803 endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E VK055_0508 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E VK055_1238 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E VK055_4925 apurinic endonuclease family protein K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E VK055_3094 nfi; endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E VK055_4162 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E VK055_3473 ligB; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E VK055_4754 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E VK055_3301 polA; DNA polymerase I, 3' --5' polymerase, 5' --3' and 3' --5' exonuclease K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E VK055_3026 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E VK055_1726 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E VK055_0033 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E VK055_1231 endonuclease of nucleotide excision repair K05984 cho; excinuclease Cho [EC:3.1.25.-]
E VK055_3163 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E VK055_3301 polA; DNA polymerase I, 3' --5' polymerase, 5' --3' and 3' --5' exonuclease K02335 polA; DNA polymerase I [EC:2.7.7.7]
E VK055_3473 ligB; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E VK055_4754 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F VK055_3110 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F VK055_3109 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F VK055_3778 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F VK055_3471 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F VK055_1352 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E VK055_4422 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E VK055_2896 mutL; mutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E VK055_4284 mutH; DNA mismatch repair endonuclease MutH K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E VK055_5051 exonuclease I, 3' --5' specific deoxyribophosphodiesterase K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E VK055_4663 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E VK055_2180 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E VK055_0088 exonuclease family protein K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D DNA polymerase III holoenzyme
E VK055_2368 DNA polymerase III, &alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E VK055_3360 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E VK055_2795 DNA polymerase III chi subunit, HolC family protein K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E VK055_1860 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E VK055_1368 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E VK055_2336 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E VK055_2097 dnaX; DNA polymerase III, subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E VK055_2603 holD; DNA polymerase III, psi subunit K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
E VK055_0089 holE; DNA polymerase III, &theta subunit K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
D DNA ligase
E VK055_3473 ligB; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E VK055_4754 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E VK055_3163 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E VK055_3025 ssb; ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein
E VK055_1639 dam; DNA adenine methylase family protein K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E VK055_3712 dam3; DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E VK055_5159 dam2; DNA adenine methylase family protein K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E VK055_0018 DNA mismatch endonuclease of the very short patch (VSP) mismatch repair pathway K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E VK055_4296 recB; exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E VK055_4294 recC; exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E VK055_4297 recD; exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E VK055_4485 recA; protein RecA K03553 recA; recombination protein RecA
E VK055_0071 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E VK055_0072 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E VK055_0070 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E VK055_5160 endodeoxyribonuclease RusA family protein K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
E VK055_3246 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E VK055_2100 primosomal replication priB and priC family protein K04067 priC; primosomal replication protein N''
E VK055_2621 dnaT; dnaT K02317 dnaT; DNA replication protein DnaT
E VK055_5051 exonuclease I, 3' --5' specific deoxyribophosphodiesterase K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E VK055_2218 ATP-dependent dsDNA exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50
E VK055_2217 sbcD; exonuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E VK055_4485 recA; protein RecA K03553 recA; recombination protein RecA
E VK055_2587 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E VK055_3361 recF; ssDNA and dsDNA binding, ATP binding protein K03629 recF; DNA replication and repair protein RecF
E VK055_3468 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E VK055_4162 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E VK055_4611 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E VK055_2095 recR; recombination protein RecR K06187 recR; recombination protein RecR
E VK055_4562 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E VK055_2220 rdgC; nonspecific DNA binding protein; nucleoid component K03554 rdgC; recombination associated protein RdgC
E VK055_5155 exonuclease, RdgC family protein K03554 rdgC; recombination associated protein RdgC
E VK055_0071 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E VK055_0072 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E VK055_0070 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E VK055_0385 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
E VK055_4904 helicase conserved C-terminal domain protein K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E VK055_2218 ATP-dependent dsDNA exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50
E VK055_2217 sbcD; exonuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
E VK055_2790 putative ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F VK055_4875 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F VK055_3362 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F VK055_1182 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F VK055_3092 hupA; DNA-binding protein HU-&alpha K05787 hupA; DNA-binding protein HU-alpha
F VK055_2151 hupB; DNA-binding protein HU-&beta, NS1 K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F VK055_4162 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F VK055_4611 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F VK055_2095 recR; recombination protein RecR K06187 recR; recombination protein RecR
F VK055_3473 ligB; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F VK055_4754 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F VK055_3805 fis; fis transcriptional dual regulator K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F VK055_0282 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
F VK055_1545 ihfB; integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F VK055_5051 exonuclease I, 3' --5' specific deoxyribophosphodiesterase K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F VK055_3158 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F VK055_3026 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F VK055_1726 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F VK055_0251 hns; H-NS transcriptional dual regulator K03746 hns; DNA-binding protein H-NS
F VK055_1420 putative h-NS-like DNA-binding protein K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D VK055_2319 impB/mucB/samB family protein K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D VK055_1277 SOS mutagenesis and repair K03502 umuC; DNA polymerase V
D VK055_1278 umuD; SOS mutagenesis error-prone repair processed to UmuD' forms complex with UmuC K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D VK055_4485 recA; protein RecA K03553 recA; recombination protein RecA
D VK055_3042 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D VK055_4562 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D VK055_2515 DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D VK055_3025 ssb; ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein
D VK055_3376 putative dNA-damage-inducible protein D K14623 dinD; DNA-damage-inducible protein D
D VK055_1393 dinI-like family protein K12149 dinI; DNA-damage-inducible protein I
D VK055_4486 recX family protein K03565 recX; regulatory protein
D VK055_2668 hypothetical protein K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D VK055_3199 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D VK055_1495 helD; DNA helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4]
D VK055_1699 DEAD/DEAH box helicase family protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D VK055_0125 DEAD/DEAH box helicase family protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D VK055_2468 mutT; 8-oxo-dGTPase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D VK055_3489 dut; dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D VK055_4873 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D VK055_4511 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D VK055_4872 nrdB; nrdB K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D VK055_4510 nrdF2; ribonucleoside-diphosphate reductase subunit beta nrdF2 K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024