+C Peptidases and inhibitors KO
#
Peptidases and Inhibitors - Lysobacter antibioticus 76
%
!
AAspartic peptidases
B Family A1: pepsin family
B Family A2: retropepsin family
B Family A5: thermopsin family
B Family A8: signal peptidase II family
C LA76x_1991 lspA; signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36]
B Family A22: presenilin family
B Family A24: type IV prepilin peptidase family
C LA76x_1186 type IV leader peptidase family protein K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
B Family A25: gpr protease family
B Family A26: omptin family
B Family A28
B Family A31: HybD endopeptidase family
B Family A36
#
ACysteine peptidases
B Family C1: papain family
B Family C2: calpain family
B Family C3: picornain family
B Family C4: NIa protease family
B Family C5
B Family C9
B Family C10: streptopain family
B Family C11: clostripain family
B Family C12: ubiquitin C-terminal hydrolase family
B Family C13: legumain family
B Family C14: caspase family
B Family C15: pyroglutamyl peptidase I family
C LA76x_2084 pcp; pyroglutamyl-peptidase I K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3]
B Family C16
B Family C19: ubiquitin-specific protease family
B Family C25: gingipain family
B Family C26: gamma-glutamyl hydrolase family
C LA76x_2349 guaA; guaA GMP synthetase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C LA76x_2100 glutamine amidotransferase class-I family protein K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C LA76x_0146 glutamine amidotransferase class-I family protein K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C LA76x_3075 glutamine amidotransferase class-I family protein K07010 K07010; putative glutamine amidotransferase
B Family C27
B Family C30
B Family C37
B Family C39
C LA76x_0764 ABC transporter family protein K13409 cvaB; ATP-binding cassette, subfamily B, bacterial CvaB/MchF/RaxB
B Family C40
B Family C44
C LA76x_3834 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C LA76x_0092 FMN-dependent dehydrogenase family protein K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
C LA76x_4367 glmS; glutamine-fructose-6-phosphate transaminase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C LA76x_4872 glutamine-fructose-6-phosphate transaminase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C LA76x_2191 asnB; asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C LA76x_1936 asnB; asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
B Family C45
B Family C46: hedgehog family
B Family C47: staphopain family
B Family C48: Ulp1 endopeptidase family
B Family C50: separase family
B Family C54: Aut2 peptidase family
B Family C55: YopJ protease family
B Family C56: PfpI endopeptidase family
B Family C57: vaccinia virus I7 peptidase family
B Family C58
B Family C59
B Family C60
B Family C63
B Family C64
B Family C65
B Family C67
B Family C69
B Family C70
B Family C75
B Family C76
B Family C78
B Family C79
B Family C82
B Family C83
B Family C85
B Family C86
B Family C88
B Family C89
B Family C97
B Family C98
B Family C110
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AGlutamic peptidases
B Family G1
B Family G4
B Family G5: prenyl protease 2 family
C LA76x_0005 CAAX protease self-immunity family protein K07052 K07052; CAAX protease family protein
C LA76x_1099 CAAX protease self-immunity family protein K07052 K07052; CAAX protease family protein
C LA76x_2010 CAAX protease self-immunity family protein K07052 K07052; CAAX protease family protein
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AMetallo peptidases
B Family M1
C LA76x_0824 cold-active aminopeptidase K01254 LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
C LA76x_3777 peptidase M1 family protein K01256 pepN; aminopeptidase N [EC:3.4.11.2]
B Family M2
C LA76x_3622 ace; angiotensin-converting enzyme K01283 ACE; peptidyl-dipeptidase A [EC:3.4.15.1]
B Family M3
C LA76x_2155 peptidase M3 family protein K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]
B Family M4: thermolysin family
C LA76x_2473 nprV; neutral protease K08604 hap; vibriolysin [EC:3.4.24.25]
C LA76x_2475 zinc metalloproteinase K08604 hap; vibriolysin [EC:3.4.24.25]
C LA76x_5123 thermolysin metallopeptidase, catalytic domain protein K20273 zmpA; zinc metalloprotease ZmpA
C LA76x_0021 thermolysin metallopeptidase, catalytic domain protein K20273 zmpA; zinc metalloprotease ZmpA
C LA76x_3720 npr; thermolysin domain protein K20273 zmpA; zinc metalloprotease ZmpA
C LA76x_3722 thermolysin metallopeptidase, catalytic domain protein K20273 zmpA; zinc metalloprotease ZmpA
B Family M5: mycolysin family
B Family M6: immune inhibitor A family
B Family M7: snapalysin family
B Family M8: leishmanolysin family
B Family M9
C LA76x_4670 peptidase MA superfamily protein K01387 colA; microbial collagenase [EC:3.4.24.3]
C LA76x_0536 peptidase MA superfamily protein K01387 colA; microbial collagenase [EC:3.4.24.3]
B Family M10
B Family M12: astacin/adamalysin family
B Family M13: neprilysin family
C LA76x_1829 peptidase M13 family protein K07386 pepO; putative endopeptidase [EC:3.4.24.-]
C LA76x_1830 peptidase M13 family protein K07386 pepO; putative endopeptidase [EC:3.4.24.-]
C LA76x_3138 endopeptidase, peptidase family M13 K07386 pepO; putative endopeptidase [EC:3.4.24.-]
C LA76x_0541 peptidase M13 family protein K07386 pepO; putative endopeptidase [EC:3.4.24.-]
C LA76x_3153 peptidase M13 family protein K07386 pepO; putative endopeptidase [EC:3.4.24.-]
B Family M14: carboxypeptidase A family
C LA76x_3978 lieA; leupeptin-inactivating enzyme 1 K05996 cpt; carboxypeptidase T [EC:3.4.17.18]
B Family M15: zinc D-Ala-D-Ala carboxypeptidase family
C LA76x_3608 D-alanyl-D-alanine carboxypeptidase family protein K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
C LA76x_0750 D-ala-D-ala dipeptidase family protein K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
C LA76x_2028 D-alanyl-D-alanine carboxypeptidase family protein K17733 cwlK; peptidoglycan LD-endopeptidase CwlK [EC:3.4.-.-]
C LA76x_1336 D-alanyl-D-alanine carboxypeptidase family protein K17733 cwlK; peptidoglycan LD-endopeptidase CwlK [EC:3.4.-.-]
B Family M16: pitrilysin family
C LA76x_2887 peptidase M16 inactive domain protein K07263 pqqL; zinc protease [EC:3.4.24.-]
C LA76x_4677 putative zinc protease K07263 pqqL; zinc protease [EC:3.4.24.-]
C LA76x_3733 peptidase M16 inactive domain protein K07263 pqqL; zinc protease [EC:3.4.24.-]
C LA76x_3734 peptidase M16 inactive domain protein K07263 pqqL; zinc protease [EC:3.4.24.-]
C LA76x_4704 peptidase M16 inactive domain protein K07263 pqqL; zinc protease [EC:3.4.24.-]
B Family M17: leucyl aminopeptidase family
C LA76x_0861 cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
C LA76x_1114 putative cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
B Family M18
B Family M19: membrane dipeptidase family
C LA76x_3822 membrane dipeptidase family protein K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
C LA76x_4584 membrane dipeptidase family protein K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
B Family M20
C LA76x_1934 dapE; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
B Family M23
C LA76x_3114 beta-lytic metalloendopeptidase K20749 E3.4.24.32; beta-lytic metalloendopeptidase [EC:3.4.24.32]
B Family M24
C LA76x_1929 map; methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C LA76x_1141 map; methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C LA76x_4184 pepQ; xaa-Pro dipeptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]
C LA76x_4189 aminopeptidase P, N-terminal domain protein K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
B Family M26
B Family M27
B Family M28: aminopeptidase Y family
C LA76x_3976 peptidase M20/M25/M40 family protein K05994 E3.4.11.10; bacterial leucyl aminopeptidase [EC:3.4.11.10]
C LA76x_2290 peptidase M28 family protein K19702 E3.4.11.24; aminopeptidase S [EC:3.4.11.24]
C LA76x_1378 peptidase M28 K01302 CPQ; carboxypeptidase Q [EC:3.4.17.-]
B Family M29: aminopeptidase T family
B Family M32: carboxypeptidase Taq family
B Family M34: anthrax lethal factor family
B Family M35: deuterolysin family
C LA76x_2180 mep; peptidyl-Lys metalloendopeptidase K08646 MEP; peptidyl-Lys metalloendopeptidase [EC:3.4.24.20]
C LA76x_2225 mep; peptidyl-Lys metalloendopeptidase K08646 MEP; peptidyl-Lys metalloendopeptidase [EC:3.4.24.20]
B Family M36: fungalysin family
B Family M38: beta-aspartyl dipeptidase family
B Family M41: FtsH endopeptidase family
C LA76x_3685 hflB; ftsH HflB K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
B Family M42: glutamyl aminopeptidase family
B Family M43: cytophagalysin family
B Family M44
B Family M48: Ste24 endopeptidase family
C LA76x_3299 htpX; heat shock, integral membrane protein K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
C LA76x_3553 peptidase M48 family protein K01423 bepA; beta-barrel assembly-enhancing protease [EC:3.4.-.-]
B Family M49: dipeptidyl-peptidase III family
B Family M50: S2P protease family
C LA76x_1916 rseP; RIP metalloprotease RseP K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
B Family M54
B Family M55: DppA aminopeptidase family
B Family M56
C LA76x_4138 blaR1 peptidase M56 family protein K02172 blaR1; bla regulator protein blaR1
C LA76x_2576 peptidase M48 family protein K02172 blaR1; bla regulator protein blaR1
C LA76x_1923 blaR1 peptidase M56 family protein K02172 blaR1; bla regulator protein blaR1
B Family M67
B Family M72
C LA76x_1409 peptidyl-Asp metalloendopeptidase domain protein K23743 E3.4.24.33; peptidyl-Asp metalloendopeptidase [EC:3.4.24.33]
C LA76x_3981 lieA; leupeptin-inactivating enzyme 1 K23743 E3.4.24.33; peptidyl-Asp metalloendopeptidase [EC:3.4.24.33]
C LA76x_0516 bacterial pre-peptidase C-terminal domain protein K23743 E3.4.24.33; peptidyl-Asp metalloendopeptidase [EC:3.4.24.33]
C LA76x_1092 FG-GAP repeat family protein K23743 E3.4.24.33; peptidyl-Asp metalloendopeptidase [EC:3.4.24.33]
B Family M73
B Family M74
B Family M80
B Family M82
B Family M85
B Family M88
B Family M90
C LA76x_0988 phosphoenolpyruvate:glucose-phosphotransferase regulator family protein K09933 mtfA; MtfA peptidase
#
AAsparagine peptide lyases
B Family N1
B Family N8
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AMixed peptidases
B Family P1: DmpA aminopeptidase family
B Family P2
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ASerine peptidases
B Family S1: chymotrypsin family
C LA76x_3488 peptidase Do family protein K04771 degP; serine protease Do [EC:3.4.21.107]
C LA76x_0867 peptidase Do family protein K04772 degQ; serine protease DegQ [EC:3.4.21.-]
C LA76x_3979 lieA; leupeptin-inactivating enzyme 1 K01337 E3.4.21.50; lysyl endopeptidase [EC:3.4.21.50]
C LA76x_3980 lieA; leupeptin-inactivating enzyme 1 K01337 E3.4.21.50; lysyl endopeptidase [EC:3.4.21.50]
C LA76x_1946 prpL; lysyl endopeptidase K01337 E3.4.21.50; lysyl endopeptidase [EC:3.4.21.50]
C LA76x_0205 trypsin family protein K01337 E3.4.21.50; lysyl endopeptidase [EC:3.4.21.50]
C LA76x_3156 alpha-LP; alpha-lytic protease K18546 sprC; streptogrisin C [EC:3.4.21.-]
C LA76x_3157 alpha-LP; alpha-lytic protease K18546 sprC; streptogrisin C [EC:3.4.21.-]
C LA76x_4363 alpha-LP; alpha-lytic protease K18546 sprC; streptogrisin C [EC:3.4.21.-]
C LA76x_3467 alpha-LP; alpha-lytic protease K20136 alpha-LP; alpha-lytic endopeptidase [EC:3.4.21.12]
B Family S3: togavirin family
B Family S6
B Family S7: flavivirin family
B Family S8: subtilisin family
C LA76x_3325 subtilase family protein K14645 K14645; serine protease [EC:3.4.21.-]
C LA76x_3326 bprV; extracellular basic protease K14645 K14645; serine protease [EC:3.4.21.-]
C LA76x_2636 bprV; extracellular basic protease K14645 K14645; serine protease [EC:3.4.21.-]
C LA76x_0534 bprV; extracellular basic protease K14645 K14645; serine protease [EC:3.4.21.-]
C LA76x_3983 bprV; extracellular basic protease K14645 K14645; serine protease [EC:3.4.21.-]
C LA76x_3985 bprV; extracellular basic protease K14645 K14645; serine protease [EC:3.4.21.-]
C LA76x_4821 subtilase family protein K14645 K14645; serine protease [EC:3.4.21.-]
C LA76x_1980 subtilase family protein K14645 K14645; serine protease [EC:3.4.21.-]
C LA76x_0507 protease 1 K14645 K14645; serine protease [EC:3.4.21.-]
C LA76x_3124 lieA; leupeptin-inactivating enzyme 1 K14645 K14645; serine protease [EC:3.4.21.-]
C LA76x_3411 phoA; alkaline phosphatase domain protein K14645 K14645; serine protease [EC:3.4.21.-]
C LA76x_2224 subtilase family protein K14645 K14645; serine protease [EC:3.4.21.-]
C LA76x_0179 hypothetical protein K17734 aprX; serine protease AprX [EC:3.4.21.-]
C LA76x_2941 subtilase family protein K17734 aprX; serine protease AprX [EC:3.4.21.-]
B Family S9: prolyl oligopeptidase family
C LA76x_0806 putative PEPTIDASE K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26]
C LA76x_0269 dipeptidyl peptidase IV K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]
C LA76x_0807 prolyl oligopeptidase family protein K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
B Family S10
B Family S11: D-Ala-D-Ala carboxypeptidase A family
C LA76x_0843 dacC; penicillin-binding protein 6 K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
B Family S12: D-Ala-D-Ala carboxypeptidase B family
B Family S13: D-Ala-D-Ala peptidase C family
B Family S14: ClpP endopeptidase family
C LA76x_1874 clpP; ATP-dependent Clp endopeptidase, proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
B Family S15
B Family S16: lon protease family
C LA76x_1876 lon; ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
B Family S21: assemblin family
B Family S24: LexA family
C LA76x_2032 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
C LA76x_2930 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
B Family S26: signal peptidase I family
C LA76x_3486 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
B Family S28
B Family S31
B Family S32
B Family S33
C LA76x_3414 pip; prolyl aminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
C LA76x_4008 pip; prolyl aminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
B Family S41: C-terminal processing peptidase family
C LA76x_4608 C-terminal processing peptidase family protein K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
C LA76x_0850 C-terminal processing peptidase family protein K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
B Family S45
C LA76x_2115 penicillin amidase family protein K01434 pac; penicillin G amidase [EC:3.5.1.11]
C LA76x_2642 penicillin amidase family protein K01434 pac; penicillin G amidase [EC:3.5.1.11]
C LA76x_1935 penicillin amidase family protein K01434 pac; penicillin G amidase [EC:3.5.1.11]
B Family S49: protease IV family
C LA76x_0347 sppA; signal peptide peptidase SppA, 67K type K04773 sppA; protease IV [EC:3.4.21.-]
B Family S50
B Family S51
C LA76x_4754 peptidase S51 family protein K13282 cphB; cyanophycinase [EC:3.4.15.6]
B Family S53
B Family S54: Rhomboid family
B Family S55: SpoIVB peptidase family
B Family S62
B Family S66
B Family S77: phage prohead processing peptidase family
B Family S78
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AThreonine peptidases
B Family T1: proteasome family
C LA76x_0814 hslV; ATP-dependent protease HslVU, peptidase subunit K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
B Family T2
C LA76x_4755 iaaA K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
B Family T3: gamma-glutamyltransferase family
C LA76x_4850 ggt; gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C LA76x_1788 ggt; gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
#
APeptidases of unknown catalytic type
B Family U32
B Family U62
C LA76x_1894 modulator of DNA gyrase family protein K03592 pmbA; PmbA protein
C LA76x_2549 modulator of DNA gyrase family protein K03568 tldD; TldD protein
C LA76x_2551 modulator of DNA gyrase family protein K03568 tldD; TldD protein
C LA76x_1892 modulator of DNA gyrase family protein K03568 tldD; TldD protein
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APeptidase inhibitors
B Family I1: Kazal family
B Family I2: Kunitz - BPTI family
B Family I4: serpin family
B Family I11: ecotin family
B Family I17: WAP-type family
B Family I25: cystatin family
B Family I27: calpastatin family
B Family I32: IAP family
B Family I34: IA3 family
B Family I35: timp family
B Family I39: alpha2M family
C LA76x_2476 alpha-2-macroglobulin N-terminal region family protein K06894 yfhM; alpha-2-macroglobulin
C LA76x_3032 alpha-2-macroglobulin MG1 domain protein K06894 yfhM; alpha-2-macroglobulin
B Family I47: latexin family
B Family I49: proSAAS family
B Family I51: IC family
B Family I57: staphostatin B family
B Family I63
B Family I80
B Family I87
C LA76x_3678 hflC; hflC protein K04087 hflC; modulator of FtsH protease HflC
C LA76x_3679 hflK; hflK protein K04088 hflK; modulator of FtsH protease HflK
B Family I93
!
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 29, 2024
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Classification taken and modified from MEROPS