+F Repair protein KO
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DNA Repair and Recombination Proteins - Leptospira borgpetersenii L550
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E LBL_2482 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LBL_1521 mutY; A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LBL_1428 Endonuclease III related protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E LBL_1401 DNA or RNA helicase of superfamily II K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
D LBL_1631 Nuclease S1 K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D LBL_0038 Hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LBL_0941 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LBL_2228 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D LBL_0141 ada; Methylated-DNA--[protein]-cysteine S-methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E LBL_2482 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LBL_0362 Uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E LBL_2417 alkA; DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E LBL_1521 mutY; A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LBL_1428 Endonuclease III related protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E LBL_1888 xthA; Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E LBL_1061 recJ; Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E LBL_2907 lig; DNA ligase (NAD+) (contains BRCT domain type II) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E LBL_0548 polA; DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E LBL_1629 uvrA; Excinuclease ABC, subunit A K03701 uvrA; excinuclease ABC subunit A
E LBL_0755 uvrB; Helicase subunit of the DNA excision repair complex K03702 uvrB; excinuclease ABC subunit B
E LBL_1431 uvrC; Excinuclease ABC, subunit C K03703 uvrC; excinuclease ABC subunit C
E LBL_1581 uvrD-2; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LBL_0802 uvrD-3; DNA/RNA helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LBL_1531 uvrD-1; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LBL_0548 polA; DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
E LBL_2907 lig; DNA ligase (NAD+) (contains BRCT domain type II) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F LBL_0743 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F LBL_0744 rpoC; DNA-directed RNA polymerase, beta subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F LBL_0480 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F LBL_0440 rpoA-1; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F LBL_1885 mfd; Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E LBL_1417 mutS; DNA mismatch repair ATPase K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E LBL_2218 mutL; DNA mismatch repair enzyme (predicted ATPase) K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E LBL_1499 xseA; Exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E LBL_1498 xseB; Exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E LBL_0288 dnaE; DNA-directed DNA polymerase, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E LBL_0005 dnaN; DNA-directed DNA polymerase, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E LBL_0015 holA; DNA-directed DNA polymerase, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E LBL_0003 dnaX-1; DNA polymerase III gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E LBL_0064 dnaX-2; DNA polymerase III, gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E LBL_2907 lig; DNA ligase (NAD+) (contains BRCT domain type II) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E LBL_1581 uvrD-2; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LBL_0802 uvrD-3; DNA/RNA helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LBL_1531 uvrD-1; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LBL_2444 Single-strand DNA binding protein family K03111 ssb; single-strand DNA-binding protein
E LBL_1246 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E LBL_1347 Site-specific DNA-methyltransferase (adenine-specific), dam K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E LBL_2395 recB; Exodeoxyribonuclease V, beta chain K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E LBL_2394 recC; Exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E LBL_2396 recD; Exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E LBL_1569 recA; RecA recombinase K03553 recA; recombination protein RecA
E LBL_1063 ruvA; Holliday junction specific DNA binding protein K03550 ruvA; holliday junction DNA helicase RuvA
E LBL_2317 ruvB; Holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E LBL_2536 ruvC; Crossover junction endoribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E LBL_1664 priA; Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E LBL_1569 recA; RecA recombinase K03553 recA; recombination protein RecA
E LBL_0827 sms; ATP-dependent serine protease K04485 radA; DNA repair protein RadA/Sms
E LBL_0006 recF; Recombinational DNA repair ATPase K03629 recF; DNA replication and repair protein RecF
E LBL_2677 ATP-dependent DNA helicase, recG-related K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E LBL_1061 recJ; Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E LBL_1254 recO; Recombinational DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
E LBL_0066 recR; Recombinational DNA repair protein K06187 recR; recombination protein RecR
E LBL_1527 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E LBL_1063 ruvA; Holliday junction specific DNA binding protein K03550 ruvA; holliday junction DNA helicase RuvA
E LBL_2317 ruvB; Holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E LBL_2536 ruvC; Crossover junction endoribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E LBL_0657 Conserved hypothetical protein K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F LBL_0254 DNA topoisomerase (ATP-hydrolyzing), subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F LBL_0009 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F LBL_0253 DNA topoisomerase (ATP-hydrolyzing), subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F LBL_0008 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F LBL_1279 topA; DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F LBL_1061 recJ; Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F LBL_1254 recO; Recombinational DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
F LBL_0066 recR; Recombinational DNA repair protein K06187 recR; recombination protein RecR
F LBL_2907 lig; DNA ligase (NAD+) (contains BRCT domain type II) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F LBL_2393 recQ-2; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F LBL_2780 recQ-1; DNA helicase, Superfamily II K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F LBL_1629 uvrA; Excinuclease ABC, subunit A K03701 uvrA; excinuclease ABC subunit A
F LBL_0755 uvrB; Helicase subunit of the DNA excision repair complex K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D LBL_1569 recA; RecA recombinase K03553 recA; recombination protein RecA
D LBL_1071 lexA; Repressor lexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D LBL_1527 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D LBL_2444 Single-strand DNA binding protein family K03111 ssb; single-strand DNA-binding protein
D LBL_1246 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D LBL_1831 DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D LBL_0038 Hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LBL_0941 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LBL_2228 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D LBL_1495 nrdA; Ribonucleoside-triphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024