+F Repair protein KO
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DNA Repair and Recombination Proteins - Lacticaseibacillus paracasei BL23
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E LCABL_11610 ung; Uracil-DNA glycosylase (UDG) K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LCABL_17590 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E LCABL_07540 mutY; A/G-specific adenine glycosylase (Putative) K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LCABL_17050 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E LCABL_02830 srmB; Superfamily II DNA and RNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D LCABL_27440 mutT; Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LCABL_27720 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LCABL_25100 dut; Deoxyuridine 5-triphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D LCABL_01360 ogt; Methylated-DNA--[protein]-cysteine S-methyltransferase K13531 adaB; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E LCABL_11610 ung; Uracil-DNA glycosylase (UDG) K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LCABL_17590 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E LCABL_07540 mutY; A/G-specific adenine glycosylase (Putative) K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LCABL_23940 tag1; 3-methyl-adenine DNA glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E LCABL_05000 tag1; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E LCABL_19270 mutM; Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23) (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (AP lyase mutM) K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E LCABL_17050 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E LCABL_11670 exoA; Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E LCABL_17390 nfo; Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E LCABL_17720 recJ; Single-strand DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E LCABL_12200 ligA; DNA ligase (Polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E LCABL_19280 polA; DNA-directed DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E LCABL_28050 uvrA3; Excinuclease ABC, subunit A K03701 uvrA; excinuclease ABC subunit A
E LCABL_10710 uvrA1; Excinuclease ABC, subunit A K03701 uvrA; excinuclease ABC subunit A
E LCABL_10700 uvrB; UvrABC system protein B (Protein uvrB) (Excinuclease ABC subunit B) K03702 uvrB; excinuclease ABC subunit B
E LCABL_15670 uvrC; UvrABC system protein C (Protein uvrC) (Excinuclease ABC subunit C) K03703 uvrC; excinuclease ABC subunit C
E LCABL_12190 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LCABL_21600 rep; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LCABL_19280 polA; DNA-directed DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E LCABL_12200 ligA; DNA ligase (Polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F LCABL_26820 rpoB; DNA-directed RNA polymerase subunit beta (RNAP subunit beta) (Transcriptase subunit beta) (RNA polymerase subunit beta) K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F LCABL_26800 rpoC; DNA-directed RNA polymerase subunit beta (RNAP subunit beta) (Transcriptase subunit beta) (RNA polymerase subunit beta) K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F LCABL_26450 rpoA; DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (Transcriptase subunit alpha) (RNA polymerase subunit alpha) K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F LCABL_27400 rpoE; DNA-directed RNA polymerase, delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
F LCABL_18430 rpoZ; DNA-directed RNA polymerase subunit omega (RNAP omega subunit) (Transcriptase subunit omega) (RNA polymerase omega subunit) K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F LCABL_27140 mfd; Transcription-repair coupling factor (TRCF) K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E LCABL_24170 mutS; DNA mismatch repair protein mutS K03555 mutS; DNA mismatch repair protein MutS
E LCABL_08520 mutS; DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E LCABL_24160 mutL; DNA mismatch repair protein mutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E LCABL_18540 xseA; Exodeoxyribonuclease 7 large subunit (Exodeoxyribonuclease VII large subunit) (Exonuclease VII large subunit) K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E LCABL_18530 xseB; Exodeoxyribonuclease 7 small subunit (Exodeoxyribonuclease VII small subunit) (Exonuclease VII small subunit) K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E LCABL_15830 dnaE; DNA-directed DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E LCABL_17910 polC; DNA polymerase III polC-type (PolIII) K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E LCABL_00020 dnaN; DNA-directed DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E LCABL_15520 holA; DNA-directed DNA polymerase III, delta chain K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E LCABL_24390 holB; DNA-directed DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E LCABL_11660 dnaQ; DNA-directed DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E LCABL_24450 dnaX; DNA-directed DNA polymerase III, gamma/tau subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E LCABL_12200 ligA; DNA ligase (Polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E LCABL_12190 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LCABL_21600 rep; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LCABL_00080 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E LCABL_00100 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E LCABL_22620 recD; Putative exodeoxyribonuclease V K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E LCABL_15260 recD; Exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E LCABL_28180 recA; Protein recA K03553 recA; recombination protein RecA
E LCABL_10360 recA; Protein recA (Recombinase A) K03553 recA; recombination protein RecA
E LCABL_08330 ruvA; Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E LCABL_08340 ruvB; Holliday junction ATP-dependent DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E LCABL_18410 priA; Primosomal replication protein N (Factor Y) K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E LCABL_07500 sbcC; Exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50
E LCABL_07490 sbcD; Exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E LCABL_28180 recA; Protein recA K03553 recA; recombination protein RecA
E LCABL_10360 recA; Protein recA (Recombinase A) K03553 recA; recombination protein RecA
E LCABL_25090 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E LCABL_00040 recF; DNA replication and repair protein recF K03629 recF; DNA replication and repair protein RecF
E LCABL_18300 recG; ATP-dependent DNA helicase, RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E LCABL_17720 recJ; Single-strand DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E LCABL_17300 recO; DNA repair protein recO (Recombination protein O) K03584 recO; DNA repair protein RecO (recombination protein O)
E LCABL_24430 recR; Recombination protein recR K06187 recR; recombination protein RecR
E LCABL_18490 recN; DNA repair and genetic recombination protein N K03631 recN; DNA repair protein RecN (Recombination protein N)
E LCABL_17020 recU; Holliday junction resolvase recU (Recombination protein U homolog) K03700 recU; recombination protein U
E LCABL_08330 ruvA; Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E LCABL_08340 ruvB; Holliday junction ATP-dependent DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E LCABL_17110 rexA; ATP-dependent nuclease, subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E LCABL_17120 rexB; ATP-dependent exonuclease, subunit B (ATP-dependent exonuclease, subunit B) K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E LCABL_07500 sbcC; Exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50
E LCABL_07490 sbcD; Exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
E LCABL_14640 Putative uncharacterized protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F LCABL_00060 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F LCABL_00050 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F LCABL_16250 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F LCABL_16010 hbsU; Histone-like DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F LCABL_09680 recT; RecT protein K07455 recT; recombination protein RecT
F LCABL_13050 recT; RecT protein K07455 recT; recombination protein RecT
F LCABL_17720 recJ; Single-strand DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F LCABL_17300 recO; DNA repair protein recO (Recombination protein O) K03584 recO; DNA repair protein RecO (recombination protein O)
F LCABL_24430 recR; Recombination protein recR K06187 recR; recombination protein RecR
F LCABL_12200 ligA; DNA ligase (Polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F LCABL_15960 recQ1; ATP-dependent DNA helicase (RecQ) K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F LCABL_12450 recQ1; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F LCABL_28050 uvrA3; Excinuclease ABC, subunit A K03701 uvrA; excinuclease ABC subunit A
F LCABL_10710 uvrA1; Excinuclease ABC, subunit A K03701 uvrA; excinuclease ABC subunit A
F LCABL_10700 uvrB; UvrABC system protein B (Protein uvrB) (Excinuclease ABC subunit B) K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D LCABL_08410 dinP; DNA-damage-inducible protein P K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D LCABL_12140 uvrA; UvrA protein K03502 umuC; DNA polymerase V
C Other SOS response factors
D LCABL_28180 recA; Protein recA K03553 recA; recombination protein RecA
D LCABL_10360 recA; Protein recA (Recombinase A) K03553 recA; recombination protein RecA
D LCABL_07950 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D LCABL_18490 recN; DNA repair and genetic recombination protein N K03631 recN; DNA repair protein RecN (Recombination protein N)
D LCABL_00080 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D LCABL_00100 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D LCABL_19900 recX; Regulatory protein recX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D LCABL_17100 dinG; ATP-dependent helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D LCABL_27440 mutT; Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LCABL_27720 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LCABL_25100 dut; Deoxyuridine 5-triphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D LCABL_16920 nrdE; Ribonucleoside-diphosphate reductase, alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D LCABL_16930 nrdF; Ribonucleoside-diphosphate reductase, beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D LCABL_08430 Phosphoesterase, DHH family protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
D LCABL_29790 Exopolyphosphatase-related protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024