+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Lycorma delicatula (spotted lanternfly)
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 142319387 Rnmt; (RefSeq) RNA guanine-7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 142319543 mRNA-cap; (RefSeq) RNA guanylyltransferase and 5'-phosphatase mRNA capping enzyme K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 142321762 Cdk7; (RefSeq) cyclin-dependent kinase 7 isoform X1 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 142325935 Cmtr1; (RefSeq) cap methyltransferase 1 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 142327411 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2-like isoform X1 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 142327981 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2-like K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
D Cap binding complex
E 142330155 Cbp80; (RefSeq) nuclear cap-binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 142333088 Cbp20; (RefSeq) cap binding protein 20 isoform X1 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 142329050 Cpsf5; (RefSeq) cleavage and polyadenylation specificity factor subunit 5 isoform X1 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
D Pre-mRNA cleavage factor IIm (CFIIm)
E 142319031 cbc; (RefSeq) protein CLP1 homolog isoform X1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 142320595 Cpsf160; (RefSeq) cleavage and polyadenylation specificity factor subunit 1 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E 142324638 Cpsf100; (RefSeq) cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 142333429 Cpsf73; (RefSeq) cleavage and polyadenylation specificity factor 73 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 142319483 Clp; (RefSeq) cleavage and polyadenylation specificity factor subunit 4 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 142333056 Fip1; (RefSeq) factor interacting with poly(A) polymerase 1 isoform X1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 142318938 Wdr33; (RefSeq) WD repeat domain 33 K15542 PFS2; polyadenylation factor subunit 2
E 142318951 Wdr82; (RefSeq) WD repeat domain 82 K14962 WDR82; COMPASS component SWD2
E 142320188 serine/threonine-protein phosphatase alpha-2 isoform-like K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 142320752 serine/threonine-protein phosphatase alpha-3 isoform-like K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 142321265 serine/threonine-protein phosphatase alpha-2 isoform-like K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 142323316 serine/threonine-protein phosphatase PP1-gamma catalytic subunit B K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 142327123 serine/threonine-protein phosphatase alpha-3 isoform-like K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 142331030 serine/threonine-protein phosphatase PP1-beta catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 142331702 uncharacterized protein LOC142331702 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 142320613 Ssu72; (RefSeq) ssu72 CTD phosphatase K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 142334305 CstF64; (RefSeq) cleavage stimulation factor subunit 2 CstF64 K14407 CSTF2; cleavage stimulation factor subunit 2
E 142324001 su(f); (RefSeq) cleavage stimulation factor subunit su(f) isoform X1 K14408 CSTF3; cleavage stimulation factor subunit 3
E 142331237 Sym; (RefSeq) symplekin scaffold protein K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E 142319778 SmB; (RefSeq) small ribonucleoprotein particle protein SmB K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 142332296 SmD3; (RefSeq) small ribonucleoprotein particle protein SmD3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 142327132 SmE; (RefSeq) small ribonucleoprotein particle protein SmE K11097 SNRPE; small nuclear ribonucleoprotein E
E 142333908 SmF; (RefSeq) small ribonucleoprotein particle protein SmF K11098 SNRPF; small nuclear ribonucleoprotein F
E 142330070 SNRPG; (RefSeq) small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E 142327321 Lsm10; (RefSeq) U7 small nuclear RNA associated Lsm10 K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 142327537 Lsm11; (RefSeq) U6 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 142324638 Cpsf100; (RefSeq) cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 142333429 Cpsf73; (RefSeq) cleavage and polyadenylation specificity factor 73 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 142334305 CstF64; (RefSeq) cleavage stimulation factor subunit 2 CstF64 K14407 CSTF2; cleavage stimulation factor subunit 2
E 142331237 Sym; (RefSeq) symplekin scaffold protein K06100 SYMPK; symplekin
D DRB sensitivity inducing factor (DSIF) complex
E 142322944 spt4; (RefSeq) transcription elongation factor subunit spt4 K15171 SUPT4H1; transcription elongation factor SPT4
E 142328633 Spt5; (RefSeq) transcription elongation factor subunit Spt5 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 142323700 Mettl3; (RefSeq) methyltransferase like 3 isoform X1 K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E 142331825 Mettl14; (RefSeq) methyltransferase like 14 K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 142321360 Mettl4; (RefSeq) methyltransferase like 4 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 142324082 U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase-like isoform X1 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 142330234 fl(2)d; (RefSeq) pre-mRNA-splicing regulator female-lethal(2)D isoform X1 K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 142326117 vir; (RefSeq) VIR_N domain-containing protein isoform X1 K22910 VIRMA; protein virilizer
E 142321424 nito; (RefSeq) RNA-binding protein spenito K13190 RBM15; RNA-binding protein 15
E 142329259 uncharacterized protein LOC142329259 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 142332855 uncharacterized protein LOC142332855 isoform X1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 142319075 hrg; (RefSeq) poly(A) polymerase hiiragi isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 142317685 uncharacterized protein LOC142317685 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
E 142323664 poly(A) RNA polymerase gld-2 homolog A-like K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
E 142331134 speckle targeted PIP5K1A-regulated poly(A) polymerase-like isoform X1 K18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
D Negative regulators of mRNA 3' end processing
E 142328429 uncharacterized protein LOC142328429 K10683 BARD1; BRCA1-associated RING domain protein 1
E 142323655 swm; (RefSeq) zinc finger protein swm isoform X1 K13192 RBM26; RNA-binding protein 26
E 142329926 RNA demethylase ALKBH5-like isoform X1 K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 142317434 TBPH; (RefSeq) TAR DNA-binding protein-43 homolog K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 142330118 kin17; (RefSeq) kin17 DNA and RNA binding protein K13102 KIN; DNA/RNA-binding protein KIN17
D 142326988 methyltransferase-like protein 22 isoform X1 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 142322362 Ars2; (RefSeq) arsenic resistance protein 2 isoform X1 K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 142320841 tsu; (RefSeq) 40S ribosomal protein S12 homolog tsunagi K12876 RBM8A; RNA-binding protein 8A
E 142324058 mago; (RefSeq) mago, exon junction complex subunit K12877 MAGOH; protein mago nashi
E 142323749 Ref1; (RefSeq) RNA and export factor binding protein 1 isoform X1 K12881 THOC4; THO complex subunit 4
E 142320655 Hel25E; (RefSeq) ATP-dependent RNA helicase 25E K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 142325154 eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 142327277 coiled-coil domain-containing protein 174 K25178 CCDC174; coiled-coil domain-containing protein 174
E 142327245 Bin1; (RefSeq) histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 142325247 Pnn; (RefSeq) desmosome associated protein-like protein pinnin isoform X1 K13114 PNN; pinin
E 142319099 Acn; (RefSeq) apoptotic chromatin condensation inducer acinus isoform X1 K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus
E 142324122 RnpS1; (RefSeq) RNA-binding protein S1 isoform X1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1
D TREX complex
E 142326767 Hpr1; (RefSeq) THO complex 1-like protein Hpr1 isoform X1 K12878 THOC1; THO complex subunit 1
E 142332156 tho2; (RefSeq) THO complex subunit 2-like protein K12879 THOC2; THO complex subunit 2
E 142325658 tex; (RefSeq) THO complex 3 homolog tex K12880 THOC3; THO complex subunit 3
E 142323749 Ref1; (RefSeq) RNA and export factor binding protein 1 isoform X1 K12881 THOC4; THO complex subunit 4
E 142324283 thoc5; (RefSeq) THO complex subunit 5 isoform X1 K13174 THOC5; THO complex subunit 5
E 142322479 thoc6; (RefSeq) THO complex subunit 6 K13175 THOC6; THO complex subunit 6
E 142328019 thoc7; (RefSeq) THO complex subunit 7 isoform X1 K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 142320352 PCID2; (RefSeq) PCI domain-containing protein 2 isoform X1 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 142330309 Sem1; (RefSeq) suppressor of exocyst mutations 1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 142332101 enhancer of yellow 2 transcription factor-like isoform X1 K11368 ENY2; enhancer of yellow 2 transcription factor
D Nuclear pore complex
E 142326074 Mgtor; (RefSeq) nuclear basket protein megator isoform X1 K09291 TPR; nucleoprotein TPR
E 142328038 Rae1; (RefSeq) ribonucleic acid export 1 K14298 RAE1; mRNA export factor
E 142325252 Sec13; (RefSeq) nuclear pore and COPII coat complex component secretory 13 K14004 SEC13; protein transport protein SEC13
E 142333294 Nup37; (RefSeq) nuclear pore complex protein Nup37 isoform X1 K14302 NUP37; nuclear pore complex protein Nup37
E 142330226 nuclear pore complex protein Nup85-like isoform X1 K14304 NUP85; nuclear pore complex protein Nup85
E 142330400 nuclear pore complex protein Nup85-like K14304 NUP85; nuclear pore complex protein Nup85
E 142325648 Nup43; (RefSeq) nucleoporin 43 K14305 NUP43; nuclear pore complex protein Nup43
E 142320424 Nup50; (RefSeq) nuclear pore complex protein Nup50 K14295 NUP50; nuclear pore complex protein Nup50
E 142327290 Nup54; (RefSeq) nuclear pore complex protein Nup54 K14308 NUP54; nuclear pore complex protein Nup54
E 142322461 Nup62; (RefSeq) nucleoporin 62 isoform X1 K14306 NUP62; nuclear pore complex protein Nup62
E 142323233 mbo; (RefSeq) nuclear pore complex protein Nup88 K14318 NUP88; nuclear pore complex protein Nup88
E 142319514 nuclear pore complex protein Nup93-like K14309 NUP93; nuclear pore complex protein Nup93
E 142328219 Nup98-96; (RefSeq) nuclear pore complex protein Nup98-96 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 142328678 Nup107; (RefSeq) nuclear pore complex protein Nup107 K14301 NUP107; nuclear pore complex protein Nup107
E 142325190 Nup133; (RefSeq) nuclear pore complex protein Nup133 isoform X1 K14300 NUP133; nuclear pore complex protein Nup133
E 142327434 Nup188; (RefSeq) nuclear pore complex protein Nup188 K14311 NUP188; nuclear pore complex protein Nup188
E 142328746 Nup153; (RefSeq) nucleoporin 153 isoform X1 K14296 NUP153; nuclear pore complex protein Nup153
E 142325461 Nup154; (RefSeq) nuclear pore complex protein Nup154 isoform X1 K14312 NUP155; nuclear pore complex protein Nup155
E 142328868 Nup160; (RefSeq) nuclear pore complex protein Nup160 K14303 NUP160; nuclear pore complex protein Nup160
E 142320512 Nup35; (RefSeq) nucleoporin 35 isoform X1 K14313 NUP35; nuclear pore complex protein Nup53
E 142329352 Nup205; (RefSeq) nuclear pore complex protein Nup205 isoform X1 K14310 NUP205; nuclear pore complex protein Nup205
E 142324098 Gp210; (RefSeq) nucleoporin 210 K14314 NUP210; nuclear pore complex protein Nup210
E 142332271 Nup58; (RefSeq) nuclear pore complex protein Nup58 K14307 NUPL1; nucleoporin p58/p45
E 142332444 nucleoporin NUP42-like K14321 NUPL2; nucleoporin-like protein 2
E 142329207 Ndc1; (RefSeq) nuclear division cycle 1 K14315 NDC1; nucleoporin NDC1
E 142321527 nucleoporin SEH1-like K14299 SEH1; nucleoporin SEH1
E 142321537 nucleoporin SEH1-like K14299 SEH1; nucleoporin SEH1
E 142325146 nucleoporin SEH1-like K14299 SEH1; nucleoporin SEH1
E 142334263 aladin-like isoform X1 K14320 AAAS; aladin
E 142324208 Gle1; (RefSeq) gle1 RNA export mediator isoform X1 K18723 GLE1; nucleoporin GLE1
E 142330836 nuclear RNA export factor 1-like isoform X1 K14284 NXF; nuclear RNA export factor
E 142328632 Nxt1; (RefSeq) NTF2-related export protein 1 K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 142324211 Ran; (RefSeq) RAN, member RAS oncogene family K07936 RAN; GTP-binding nuclear protein Ran
E 142330391 Mapmodulin; (RefSeq) acidic leucine-rich nuclear phosphoprotein 32 mapmodulin K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 142323135 ELAV-like protein 3 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 142333961 Faf2; (RefSeq) fas-associated factor 2 K18726 FAF2; FAS-associated factor 2
E 142321992 TER94; (RefSeq) transitional endoplasmic reticulum ATPase TER94 K13525 VCP; transitional endoplasmic reticulum ATPase
E 142329319 protein N-lysine methyltransferase METTL21D-like isoform X1 K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 142326784 emb; (RefSeq) exportin-1 emb K14290 XPO1; exportin-1
E 142325271 Ranbp16; (RefSeq) ran-binding protein 16 isoform X1 K18460 XPO7; exportin-7
E 142322102 ran GTPase-activating protein 1-like K14319 RANGAP1; Ran GTPase-activating protein 1
D eIF4F and regulatory proteins
E 142330846 eIF4E1; (RefSeq) eukaryotic translation initiation factor 4E1 K03259 EIF4E; translation initiation factor 4E
E 142334194 eIF4EHP; (RefSeq) eukaryotic translation initiation factor 4E homologous protein isoform X1 K03259 EIF4E; translation initiation factor 4E
E 142319585 eIF4A; (RefSeq) eukaryotic translation initiation factor 4A K03257 EIF4A; translation initiation factor 4A
E 142319213 eukaryotic translation initiation factor 4 gamma 3-like isoform X1 K03260 EIF4G; translation initiation factor 4G
E 142319648 NAT1; (RefSeq) N-acetyltransferase 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 142330037 eIF4B; (RefSeq) eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 142323632 eukaryotic translation initiation factor 4H-like isoform X1 K24086 EIF4H; translation initiation factor 4H
E 142334347 Thor; (RefSeq) eukaryotic translation initiation factor 4E binding protein thor K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 142323651 uncharacterized protein LOC142323651 isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 142331027 angel; (RefSeq) protein angel isoform X1 K18729 ANGEL; protein angel
E 142317379 Fmr1; (RefSeq) synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 142320542 rig; (RefSeq) gem nuclear organelle associated protein rigor mortis isoform X1 K13133 GEMIN5; gem associated protein 5
E 142324901 orb2; (RefSeq) cytoplasmic polyadenylation element-binding protein orb2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 142330009 orb; (RefSeq) polyadenylation element binding protein orb K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 142333260 bel; (RefSeq) ATP-dependent RNA helicase bel K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 142318959 pAbp; (RefSeq) poly(A) binding protein K13126 PABPC; polyadenylate-binding protein
E 142325374 Paip2; (RefSeq) polyA-binding protein interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 142329732 superkiller complex protein 2-like K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 142329211 deformed epidermal autoregulatory factor 1-like isoform X1 K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 142332306 MCTS1; (RefSeq) malignant T-cell-amplified sequence 1 homolog K07575 MCTS; malignant T-cell-amplified sequence
E 142325151 DENR; (RefSeq) density-regulated protein K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 142317902 APOBEC1 complementation factor-like K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 142333551 Pym; (RefSeq) partner of Y14 and mago K14294 WIBG; partner of Y14 and mago
E 142324870 heterogeneous nuclear ribonucleoprotein A1, A2/B1 homolog isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 142330518 heterogeneous nuclear ribonucleoprotein A1, A2/B1 homolog isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 142323870 Rbp6; (RefSeq) RNA-binding protein 6 K14411 MSI; RNA-binding protein Musashi
E 142324953 msi; (RefSeq) RNA-binding protein musashi K14411 MSI; RNA-binding protein Musashi
E 142327417 Hrb27C; (RefSeq) heterogeneous nuclear ribonucleoprotein at 27C isoform X1 K14411 MSI; RNA-binding protein Musashi
E 142329021 HBS1; (RefSeq) translation elongation factor EF-1alpha (GTPase) HBS1 K14416 HBS1; elongation factor 1 alpha-like protein
E 142324225 pelo; (RefSeq) pelota mRNA surveillance and ribosome rescue factor K06965 PELO; protein pelota
E 142322155 Pabp2; (RefSeq) poly(A) binding protein nuclear 1 isoform X1 K14396 PABPN1; polyadenylate-binding protein 2
E 142318839 Dbp80; (RefSeq) putative ATP-dependent RNA helicase Dbp80 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 142320444 fand; (RefSeq) pre-mRNA-splicing factor SYF1 fand isoform X1 K12867 SYF1; pre-mRNA-splicing factor SYF1
E 142318786 uncharacterized protein LOC142318786 K18732 SARNP; SAP domain-containing ribonucleoprotein
E 142319013 regulator of chromosome condensation-like K11493 RCC1; regulator of chromosome condensation
E 142321803 Achl; (RefSeq) la ribonucleoprotein translational regulator Achilles K18733 LARP6; la-related protein 6
E 142328788 Pur-alpha; (RefSeq) purine-rich binding protein-alpha isoform X1 K21772 PURA; transcriptional activator protein Pur-alpha
E 142323852 uncharacterized protein LOC142323852 isoform X1 K22414 POLDIP3; polymerase delta-interacting protein 3
E 142332086 uncharacterized protein LOC142332086 K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 142326043 leukocyte receptor cluster member 8 homolog K23802 LENG8; SAC3 family protein LENG8/THP3
C Surveillance factors
D Surveillance complex
E 142324654 eRF1; (RefSeq) eukaryotic release factor 1 isoform X1 K03265 ETF1; peptide chain release factor subunit 1
E 142329938 eRF3; (RefSeq) eukaryotic translation release factor 3 K03267 ERF3; peptide chain release factor subunit 3
E 142334345 Upf1; (RefSeq) upf1 RNA helicase K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 142323132 regulator of nonsense transcripts 2-like isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 142331664 regulator of nonsense transcripts 2-like isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
D Protein phosphatase 2A
E 142334350 mts; (RefSeq) protein phosphatase 2 catalytic subunit mts K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 142326193 Pp2A-29B; (RefSeq) protein phosphatase PP2A regulatory subunit A K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 142324923 tws; (RefSeq) protein phosphatase 2 regulatory subunit tws isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 142325642 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma-like isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 142333004 uncharacterized protein LOC142333004 isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 142325064 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 142325086 wdb; (RefSeq) serine/threonine-protein phosphatase regulatory subunit widerborst isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 142326204 nonC; (RefSeq) serine/threonine-protein kinase Smg1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 142327865 Smg5; (RefSeq) smg5 nonsense mediated mRNA decay factor K11125 SMG5; protein SMG5
E 142324077 uncharacterized protein LOC142324077 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 142327904 nonsense-mediated mRNA decay factor SMG7-like K14409 SMG7; protein SMG7
E 142325241 nonsense-mediated mRNA decay factor SMG8 isoform X1 K18734 SMG8; protein SMG8
E 142331770 nonsense-mediated mRNA decay factor SMG9 isoform X1 K18735 SMG9; protein SMG9
E 142326701 putative ATP-dependent RNA helicase DHX34 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E 142323776 GTPBP1; (RefSeq) GTP-binding protein 1 isoform X1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 142329763 pumilio homolog 3-like isoform X1 K14844 PUF6; pumilio homology domain family member 6
E 142323399 didum; (RefSeq) dilute class unconventional myosin isoform X1 K10357 MYO5; myosin V
E 142321600 BicD; (RefSeq) microtubule-associated protein Bicaudal D K18739 BICD; protein bicaudal D
E 142328741 egl; (RefSeq) egl_like_exo domain-containing protein isoform X1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 142319525 actin, clone 403-like isoform X1 K05692 ACTB_G1; actin beta/gamma 1
E 142322230 actin, muscle K05692 ACTB_G1; actin beta/gamma 1
E 142329804 actin-5C K05692 ACTB_G1; actin beta/gamma 1
E 142322955 T-box-containing protein TBX6L-like K10180 TBX6; T-box protein 6
E 142318069 enhancer of split mbeta protein-like K09090 HESN; hairy and enhancer of split, invertebrate
E 142333649 hry; (RefSeq) bHLH transcriptional repressor hairy K09090 HESN; hairy and enhancer of split, invertebrate
E 142334025 dpn; (RefSeq) deadpan K09090 HESN; hairy and enhancer of split, invertebrate
E 142334239 enhancer of split mgamma protein-like K09090 HESN; hairy and enhancer of split, invertebrate
D Trans-acting binding proteins
E 142331657 Psi; (RefSeq) P-element somatic inhibitor isoform X1 K13210 FUBP; far upstream element-binding protein
E 142333344 elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 142331017 eEF1gamma; (RefSeq) elongation factor 1-gamma K03233 EEF1G; elongation factor 1-gamma
E 142319681 uncharacterized protein LOC142319681 K16220 HAX1; HCLS1-associated protein X-1
E 142320555 drongo; (RefSeq) arf GTPase activating protein drongo K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 142331502 stau; (RefSeq) double-stranded RNA-binding protein Staufen isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 142333069 heph; (RefSeq) polypyrimidine tract-binding protein 1 heph isoform X1 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 142322334 sqd; (RefSeq) RNA-binding protein squid isoform X1 K03102 SQD; squid
E 142323293 RNA-binding protein squid-like K03102 SQD; squid
E 142332578 RNA-binding protein squid-like K03102 SQD; squid
E 142324901 orb2; (RefSeq) cytoplasmic polyadenylation element-binding protein orb2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 142330009 orb; (RefSeq) polyadenylation element binding protein orb K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 142317379 Fmr1; (RefSeq) synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 142330617 mub; (RefSeq) poly(rC)-binding protein mub isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 142319077 Capr; (RefSeq) cell cycle associated protein caprin family member K18743 CAPRIN1; caprin-1
E 142325978 CUGBP Elav-like family member 1 isoform X1 K02177 BRU; bruno
E 142322202 exu; (RefSeq) maternal protein exuperantia K18745 EXU; maternal protein exuperantia
E 142319280 yps; (RefSeq) Y-box binding protein ypsilon schachtel isoform X1 K09276 YBX1; Y-box-binding protein 1
E 142326740 protein sex-lethal-like K18747 SXL; protein sex-lethal
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 142318809 pcm; (RefSeq) 5'-3' exoribonuclease pacman isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 142317436 protein argonaute-2-like K11593 ELF2C; eukaryotic translation initiation factor 2C
E 142319553 AGO1; (RefSeq) protein argonaute-1 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 142327845 protein argonaute-2-like K11593 ELF2C; eukaryotic translation initiation factor 2C
E 142330404 protein argonaute-2-like K11593 ELF2C; eukaryotic translation initiation factor 2C
E 142331175 protein argonaute-2-like isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 142330846 eIF4E1; (RefSeq) eukaryotic translation initiation factor 4E1 K03259 EIF4E; translation initiation factor 4E
E 142334194 eIF4EHP; (RefSeq) eukaryotic translation initiation factor 4E homologous protein isoform X1 K03259 EIF4E; translation initiation factor 4E
E 142334345 Upf1; (RefSeq) upf1 RNA helicase K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 142333260 bel; (RefSeq) ATP-dependent RNA helicase bel K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 142326111 me31B; (RefSeq) ATP-dependent RNA helicase me31b isoform X1 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 142318416 RNA-binding E3 ubiquitin-protein ligase MEX3C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 142327122 tral; (RefSeq) LSM14 family protein trailer hitch K18749 LSM14; protein LSM14
E 142319280 yps; (RefSeq) Y-box binding protein ypsilon schachtel isoform X1 K09276 YBX1; Y-box-binding protein 1
E 142320487 jub; (RefSeq) LIM domain-containing protein jub isoform X1 K16682 AJUBA; LIM domain-containing protein
E 142332331 helicase MOV-10-like isoform X1 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 142332554 uncharacterized protein LOC142332554 isoform X1 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 142325535 aqz; (RefSeq) aaquetzalli K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 142322312 Tnpo; (RefSeq) transportin 1 K18752 TNPO1; transportin-1
E 142326204 nonC; (RefSeq) serine/threonine-protein kinase Smg1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 142327865 Smg5; (RefSeq) smg5 nonsense mediated mRNA decay factor K11125 SMG5; protein SMG5
E 142324077 uncharacterized protein LOC142324077 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 142327904 nonsense-mediated mRNA decay factor SMG7-like K14409 SMG7; protein SMG7
E 142331073 Tis11; (RefSeq) tis11 zinc finger protein K15308 TTP; tristetraprolin
E 142330952 lin-28; (RefSeq) protein lin-28 homolog K18754 LIN28; protein lin-28
E 142318966 htt; (RefSeq) huntingtin isoform X1 K04533 HD; huntingtin
E 142329282 BicC; (RefSeq) protein bicaudal C K18756 BICC1; protein bicaudal C
E 142324870 heterogeneous nuclear ribonucleoprotein A1, A2/B1 homolog isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 142330518 heterogeneous nuclear ribonucleoprotein A1, A2/B1 homolog isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 142319971 cAMP-dependent protein kinase catalytic subunit 1-like K04345 PKA; protein kinase A [EC:2.7.11.11]
E 142327330 Pka-C1; (RefSeq) protein kinase, cAMP-dependent, catalytic subunit 1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 142332458 larp; (RefSeq) la related protein K18757 LARP1; la-related protein 1
E 142323622 uncharacterized protein LOC142323622 isoform X1 K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 142333704 m7GpppN-mRNA hydrolase-like K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 142333710 DCP1; (RefSeq) decapping mRNA 1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 142325583 LSm1; (RefSeq) U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 142328681 U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 142331431 LSm3; (RefSeq) U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 142329584 U6 snRNA-associated Sm-like protein LSm5 isoform X1 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 142320905 U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 142322212 LSm7; (RefSeq) U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 142328699 U6 snRNA-associated Sm-like protein LSm8 K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 142331606 Klc; (RefSeq) kinesin light chain isoform X1 K10407 KLC; kinesin light chain
E 142323399 didum; (RefSeq) dilute class unconventional myosin isoform X1 K10357 MYO5; myosin V
E 142322064 tubulin alpha-1 chain K07374 TUBA; tubulin alpha
E 142322289 tubulin alpha chain, testis-specific-like isoform X1 K07374 TUBA; tubulin alpha
E 142324729 tubulin alpha-3 chain-like K07374 TUBA; tubulin alpha
E 142324730 tubulin alpha chain-like K07374 TUBA; tubulin alpha
E 142325740 tubulin alpha-8 chain-like K07374 TUBA; tubulin alpha
E 142326252 tubulin alpha-1 chain-like K07374 TUBA; tubulin alpha
E 142326354 tubulin alpha-1 chain-like isoform X1 K07374 TUBA; tubulin alpha
E 142330448 tubulin alpha chain-like K07374 TUBA; tubulin alpha
E 142324901 orb2; (RefSeq) cytoplasmic polyadenylation element-binding protein orb2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 142330009 orb; (RefSeq) polyadenylation element binding protein orb K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 142320542 rig; (RefSeq) gem nuclear organelle associated protein rigor mortis isoform X1 K13133 GEMIN5; gem associated protein 5
E 142329821 gw; (RefSeq) LOW QUALITY PROTEIN: trinucleotide repeat containing adaptor protein gawky K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 142329424 Not1; (RefSeq) CCR4-NOT transcription complex subunit 1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 142328191 Rga; (RefSeq) CCR4-NOT transcription complex subunit regena K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 142323917 Not3; (RefSeq) CCR4-associated factor Not3 isoform X1 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 142329469 Cnot4; (RefSeq) CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 142320132 twin; (RefSeq) CCR4-NOT transcription complex subunit 6-like twin isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 142320465 Pop2; (RefSeq) CCR4-NOT transcription complex subunit Pop2 isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 142326962 DIS3-like exonuclease 2 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 142333581 PAN2; (RefSeq) PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 142329560 PAN3; (RefSeq) poly(A) specific ribonuclease subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 142319665 uncharacterized protein LOC142319665 K14443 TOB; protein Tob/BTG
E 142323787 Tob; (RefSeq) transducer of ERBB2 K14443 TOB; protein Tob/BTG
E 142323651 uncharacterized protein LOC142323651 isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 142322847 Patr-1; (RefSeq) protein associated with topo II related - 1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 142321577 Edc3; (RefSeq) enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 142319000 Ge-1; (RefSeq) enhancer of mRNA-decapping protein 4 homolog Ge-1 isoform X1 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 142323132 regulator of nonsense transcripts 2-like isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 142331664 regulator of nonsense transcripts 2-like isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 142320863 E3 ubiquitin-protein ligase TRIM71-like K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 142327418 Polr2G; (RefSeq) DNA-directed RNA polymerase II subunit Rpb7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 142333457 Ythdf; (RefSeq) YTH domain-containing family protein isoform X1 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 142324456 nucleolysin TIAR-like K13201 TIA1; nucleolysin TIA-1/TIAR
E 142325640 Rox8; (RefSeq) TIA1 cytotoxic granule associated RNA binding protein Rox8 K13201 TIA1; nucleolysin TIA-1/TIAR
E 142318959 pAbp; (RefSeq) poly(A) binding protein K13126 PABPC; polyadenylate-binding protein
E 142331502 stau; (RefSeq) double-stranded RNA-binding protein Staufen isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 142317379 Fmr1; (RefSeq) synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 142322333 rin; (RefSeq) ras GTPase-activating protein-binding protein 2 isoform X1 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 142333081 eIF2A; (RefSeq) eukaryotic translation initiation factor 2A isoform X1 K15026 EIF2A; translation initiation factor 2A
E 142330408 eIF3b; (RefSeq) eukaryotic translation initiation factor 3 subunit b K03253 EIF3B; translation initiation factor 3 subunit B
E 142319585 eIF4A; (RefSeq) eukaryotic translation initiation factor 4A K03257 EIF4A; translation initiation factor 4A
E 142325154 eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 142330037 eIF4B; (RefSeq) eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 142319213 eukaryotic translation initiation factor 4 gamma 3-like isoform X1 K03260 EIF4G; translation initiation factor 4G
E 142319648 NAT1; (RefSeq) N-acetyltransferase 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 142327344 ribosomal protein S6 kinase alpha-2-like isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 142334348 Rack1; (RefSeq) receptor of activated protein kinase C 1 K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 142330836 nuclear RNA export factor 1-like isoform X1 K14284 NXF; nuclear RNA export factor
E 142324519 HDAC6; (RefSeq) histone deacetylase 6 isoform X1 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
E 142319347 tudor domain-containing protein 3-like isoform X1 K18404 TDRD3; tudor domain-containing protein 3
E 142329409 Larp4B; (RefSeq) la-related protein 4B isoform X1 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 142333710 DCP1; (RefSeq) decapping mRNA 1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 142333704 m7GpppN-mRNA hydrolase-like K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 142326111 me31B; (RefSeq) ATP-dependent RNA helicase me31b isoform X1 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 142321577 Edc3; (RefSeq) enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 142319000 Ge-1; (RefSeq) enhancer of mRNA-decapping protein 4 homolog Ge-1 isoform X1 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 142322847 Patr-1; (RefSeq) protein associated with topo II related - 1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 142325583 LSm1; (RefSeq) U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 142328681 U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 142331431 LSm3; (RefSeq) U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 142329584 U6 snRNA-associated Sm-like protein LSm5 isoform X1 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 142320905 U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 142322212 LSm7; (RefSeq) U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 142328699 U6 snRNA-associated Sm-like protein LSm8 K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 142318809 pcm; (RefSeq) 5'-3' exoribonuclease pacman isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 142325095 Rat1; (RefSeq) 5'-3' exoribonuclease 2 Rat1 isoform X1 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
E 142326417 U8 snoRNA-decapping enzyme-like isoform X1 K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
D Other 5'-3' decay factors
E 142319502 m7GpppX diphosphatase-like K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 142324684 Dcps; (RefSeq) decapping enzyme, scavenger isoform X1 K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 142326101 Helz; (RefSeq) helicase with zinc finger isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 142318302 Csl4; (RefSeq) exosome component 1 Csl4 K07573 CSL4; exosome complex component CSL4
E 142317829 Rrp4; (RefSeq) exosome complex component Rrp4 isoform X1 K03679 RRP4; exosome complex component RRP4
E 142323978 Rrp40; (RefSeq) exosome complex component Rrp40 K03681 RRP40; exosome complex component RRP40
E 142334456 Ski6; (RefSeq) exosome complex component Ski6 K11600 RRP41; exosome complex component RRP41
E 142322222 Rrp46; (RefSeq) exosome complex component Rrp46 K12590 RRP46; exosome complex component RRP46
E 142330340 exosome complex component MTR3-like K12587 MTR3; exosome complex component MTR3
E 142332388 Rrp42; (RefSeq) exosome complex component Rrp42 K12589 RRP42; exosome complex component RRP42
E 142332099 exosome complex component RRP43-like isoform X1 K12586 RRP43; exosome complex component RRP43
E 142321738 Rrp45; (RefSeq) exosome complex component Rrp45 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 142328115 Dis3; (RefSeq) exosome complex exonuclease RRP44-like protein Dis3 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 142319595 Rrp6; (RefSeq) exosome component Rrp6 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 142320022 inactive pancreatic lipase-related protein 1-like K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 142323898 Rrp47; (RefSeq) ribosomal RNA processing 47 K12592 C1D; exosome complex protein LRP1
E 142320140 Mpp6; (RefSeq) M-phase phosphoprotein 6 isoform X1 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
E 142326028 putative ATP-dependent RNA helicase DDX60 isoform X1 K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
D TRAMP complex
E 142318350 terminal nucleotidyltransferase 4B-like K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 142321349 Mtr4; (RefSeq) exosome RNA helicase Mtr4 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 142329732 superkiller complex protein 2-like K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 142322448 tetratricopeptide repeat protein 37-like K12600 SKI3; superkiller protein 3
E 142330200 uncharacterized protein LOC142330200 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 142320132 twin; (RefSeq) CCR4-NOT transcription complex subunit 6-like twin isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 142329424 Not1; (RefSeq) CCR4-NOT transcription complex subunit 1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 142328191 Rga; (RefSeq) CCR4-NOT transcription complex subunit regena K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 142323917 Not3; (RefSeq) CCR4-associated factor Not3 isoform X1 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 142329469 Cnot4; (RefSeq) CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 142320465 Pop2; (RefSeq) CCR4-NOT transcription complex subunit Pop2 isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 142319210 Rcd-1; (RefSeq) required for cell differentiation 1 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 142321815 Not10; (RefSeq) CCR4-NOT transcription complex subunit 10 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 142333581 PAN2; (RefSeq) PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 142329560 PAN3; (RefSeq) poly(A) specific ribonuclease subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 142324141 pre-piRNA 3'-exonuclease trimmer-like isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 142330044 poly(A)-specific ribonuclease PARN-like isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 142331932 ATP-dependent DNA/RNA helicase DHX36-like K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 142319665 uncharacterized protein LOC142319665 K14443 TOB; protein Tob/BTG
E 142323787 Tob; (RefSeq) transducer of ERBB2 K14443 TOB; protein Tob/BTG
E 142328653 cu; (RefSeq) NADP/NADPH phosphatase nocturnin isoform X1 K18764 NOCT; nocturnin [EC:3.1.3.108]
E 142325429 3'-5' exoribonuclease 1-like K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 142319502 m7GpppX diphosphatase-like K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 142324684 Dcps; (RefSeq) decapping enzyme, scavenger isoform X1 K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 142318752 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 142326101 Helz; (RefSeq) helicase with zinc finger isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 142324784 nuclear exosome regulator NRDE2 isoform X1 K26109 NRDE2; nuclear exosome regulator NRDE2
E 142324661 protein Smaug homolog 1-like K27396 SMG; protein Smaug
E 142326976 protein Smaug homolog 2-like K27396 SMG; protein Smaug
E 142330928 protein Smaug homolog 1-like K27396 SMG; protein Smaug
E 142331172 protein Smaug homolog 1-like K27396 SMG; protein Smaug
E 142322157 focadhesin isoform X1 K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 142323157 Regnase-1; (RefSeq) zinc finger CCCH-type containing protein regnase 1 isoform X1 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 142330088 drosha; (RefSeq) ribonuclease 3 drosha K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 142327702 putative oligoribonuclease isoform X1 K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 142333563 Eno; (RefSeq) alpha-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 142325418 PNPase; (RefSeq) polyribonucleotide nucleotidyltransferase 1 K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 142317966 Pfk; (RefSeq) ATP-dependent 6-phosphofructokinase isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 142325116 Hsc70-5; (RefSeq) heat shock protein 70 cognate 5 K04043 dnaK; molecular chaperone DnaK
E 142319592 Hsp60A; (RefSeq) heat shock protein 60A K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 142317829 Rrp4; (RefSeq) exosome complex component Rrp4 isoform X1 K03679 RRP4; exosome complex component RRP4
E 142318302 Csl4; (RefSeq) exosome component 1 Csl4 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 142334456 Ski6; (RefSeq) exosome complex component Ski6 K11600 RRP41; exosome complex component RRP41
E 142332388 Rrp42; (RefSeq) exosome complex component Rrp42 K12589 RRP42; exosome complex component RRP42
D Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 27, 2025