+D Receptor KO
#
G Protein-Coupled Receptors - Leptosomus discolor (cuckoo roller)
%
!
ARhodopsin family
B Biogenic amine
C Acetylcholine (muscarinic)
D 104354445 CHRM2; muscarinic acetylcholine receptor M2 K04130 CHRM2; muscarinic acetylcholine receptor M2
D 104355054 CHRM3; LOW QUALITY PROTEIN: muscarinic acetylcholine receptor M3 K04131 CHRM3; muscarinic acetylcholine receptor M3
D 104350269 CHRM4; muscarinic acetylcholine receptor M4 K04132 CHRM4; muscarinic acetylcholine receptor M4
D 104345007 CHRM5; muscarinic acetylcholine receptor M5 K04133 CHRM5; muscarinic acetylcholine receptor M5
C Adrenaline
D 104353224 ADRA1A; alpha-1A adrenergic receptor K04135 ADRA1A; adrenergic receptor alpha-1A
D 104344749 ADRA1B; alpha-1B adrenergic receptor K04136 ADRA1B; adrenergic receptor alpha-1B
D 104342046 alpha-1D adrenergic receptor-like K04137 ADRA1D; adrenergic receptor alpha-1D
D 104340202 ADRA2A; alpha-2A adrenergic receptor K04138 ADRA2A; adrenergic receptor alpha-2A
D 104353767 ADRA2C; alpha-2C adrenergic receptor K04140 ADRA2C; adrenergic receptor alpha-2C
D 104354936 ADRB1; LOW QUALITY PROTEIN: beta-1 adrenergic receptor K04141 ADRB1; adrenergic receptor beta-1
D 104354357 ADRB2; beta-2 adrenergic receptor K04142 ADRB2; adrenergic receptor beta-2
C Dopamine
D 104348354 DRD1; D(1A) dopamine receptor K04144 DRD1; dopamine receptor D1
D 104348565 DRD2; D(2) dopamine receptor isoform X1 K04145 DRD2; dopamine receptor D2
D 104344111 DRD3; D(3) dopamine receptor K04146 DRD3; dopamine receptor D3
D 104346722 DRD4; D(4) dopamine receptor K04147 DRD4; dopamine receptor D4
D 104347152 DRD5; D(1B) dopamine receptor K05840 DRD5; dopamine receptor D5
D 104354639 D(1) dopamine receptor-like K05840 DRD5; dopamine receptor D5
D 104350281 D(1)-like dopamine receptor K05840 DRD5; dopamine receptor D5
C Dopamine and ecdysteroid
C Histamine
D 104352137 HRH1; histamine H1 receptor K04149 HRH1; histamine receptor H1
D 104347285 histamine H2 receptor-like K04150 HRH2; histamine receptor H2
D 104344841 HRH2; histamine H2 receptor K04150 HRH2; histamine receptor H2
D 104341131 histamine H3 receptor-like K04151 HRH3; histamine receptor H3
D 104340343 HRH3; histamine H3 receptor K04151 HRH3; histamine receptor H3
C Octopamine and tryamine
C Serotonin
D 104341864 LOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 1A-like K04153 HTR1; 5-hydroxytryptamine receptor 1
D 104341475 HTR1B; 5-hydroxytryptamine receptor 1B K04153 HTR1; 5-hydroxytryptamine receptor 1
D 104339870 HTR1D; 5-hydroxytryptamine receptor 1D K04153 HTR1; 5-hydroxytryptamine receptor 1
D 104355021 HTR1F; 5-hydroxytryptamine receptor 1F K04153 HTR1; 5-hydroxytryptamine receptor 1
D 104339723 HTR1E; 5-hydroxytryptamine receptor 1E K04153 HTR1; 5-hydroxytryptamine receptor 1
D 104342530 HTR2B; 5-hydroxytryptamine receptor 2B K04157 HTR2; 5-hydroxytryptamine receptor 2
D 104342179 5-hydroxytryptamine receptor 2C-like K04157 HTR2; 5-hydroxytryptamine receptor 2
D 104341460 HTR2A; 5-hydroxytryptamine receptor 2A K04157 HTR2; 5-hydroxytryptamine receptor 2
D 104348692 HTR4; 5-hydroxytryptamine receptor 4 K04160 HTR4; 5-hydroxytryptamine receptor 4
D 104350830 5-hydroxytryptamine receptor 5A-like K04161 HTR5; 5-hydroxytryptamine receptor 5
D 104354817 LOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 5A-like K04161 HTR5; 5-hydroxytryptamine receptor 5
D 104348489 HTR6; 5-hydroxytryptamine receptor 6 K04162 HTR6; 5-hydroxytryptamine receptor 6
D 104347266 5-hydroxytryptamine receptor 7-like K04163 HTR7; 5-hydroxytryptamine receptor 7
D 104349509 HTR7; 5-hydroxytryptamine receptor 7 K04163 HTR7; 5-hydroxytryptamine receptor 7
C Trace amine
D 104344395 TAAR1; trace amine-associated receptor 1 K05051 TAAR; trace amine associated receptor
D 104344397 TAAR5; LOW QUALITY PROTEIN: trace amine-associated receptor 5 K05051 TAAR; trace amine associated receptor
D 104344398 TAAR2; LOW QUALITY PROTEIN: trace amine-associated receptor 2 K05051 TAAR; trace amine associated receptor
B Peptide
C Adrenomedullin (G10D)
D 104342854 GPR182; G-protein coupled receptor 182 K04242 ADMR; adrenomedullin receptor
C Adropin
D 104346933 GPR19; probable G-protein coupled receptor 19 K04316 GPR19; G protein-coupled receptor 19
C Apelin
C Anaphylatoxin
D 104352688 C3AR1; LOW QUALITY PROTEIN: C3a anaphylatoxin chemotactic receptor K04009 C3AR1; C3a anaphylatoxin chemotactic receptor
D 104343608 C5a anaphylatoxin chemotactic receptor 1-like K04010 C5AR1; C5a anaphylatoxin chemotactic receptor 1
C Angiotensin
D 104352695 AGTR1; type-1 angiotensin II receptor K04166 AGTR1; angiotensin II receptor type 1
D 104350801 AGTR2; type-2 angiotensin II receptor K04167 AGTR2; angiotensin II receptor type 2
C BigLEN
D 104349189 GPR171; probable G-protein coupled receptor 171 K08441 GPR171; G protein-coupled receptor 171
C Bombesin
D 104341058 NMBR; neuromedin-B receptor K04168 NMBR; neuromedin B receptor
D 104354896 GRPR; gastrin-releasing peptide receptor K04169 GRPR; gastrin-releasing peptide receptor
D 104339709 BRS3; bombesin receptor subtype-3 K04170 BRS3; bombesin receptor subtype-3
C Bradykinin
D 104345429 BDKRB1; B1 bradykinin receptor K03915 BDKRB1; bradykinin receptor B1
D 104345428 BDKRB2; B2 bradykinin receptor K03916 BDKRB2; bradykinin receptor B2
C Cholecystokinin
D 104347900 cholecystokinin receptor type A-like K04194 CCKAR; cholecystokinin A receptor
C Endothelin
D 104341241 EDNRA; endothelin-1 receptor K04197 EDNRA; endothelin receptor type A
D 104345517 EDNRB; endothelin B receptor K04198 EDNRB; endothelin receptor type B
D 104350515 LOW QUALITY PROTEIN: endothelin B receptor-like K04198 EDNRB; endothelin receptor type B
C fMet-Leu-Phe
C Follicle stimulating hormone (FSH)
D 104350528 FSHR; follicle-stimulating hormone receptor K04247 FSHR; follicle stimulating hormone receptor
C Galanin
D 104345061 GALR1; galanin receptor type 1 K04230 GALR1; galanin receptor 1
D 104348080 GALR2; galanin receptor type 2 K04231 GALR2; galanin receptor 2
D 104341802 galanin receptor type 2-like K04232 GALR3; galanin receptor 3
C Ghrelin
D 104343927 LOW QUALITY PROTEIN: growth hormone secretagogue receptor type 1-like K04284 GHSR; growth hormone secretagogue receptor
D 104350066 GHSR; growth hormone secretagogue receptor type 1 isoform X1 K04284 GHSR; growth hormone secretagogue receptor
C Gonadotropin-releasing hormone (GnRH)
D 104345444 gonadotropin-releasing hormone II receptor-like K04280 GNRHR; gonadotropin-releasing hormone receptor
C Lutropin-choriogonadotropic hormone
D 104347279 LHCGR; lutropin-choriogonadotropic hormone receptor K04248 LHCGR; lutropin-choriogonadotropic hormone receptor
C Melanin-concentrating hormone (MCH)
D 104347546 LOW QUALITY PROTEIN: melanin-concentrating hormone receptor 1-like K04320 MCHR1; melanin-concentrating hormone receptor 1
D 104353872 melanin-concentrating hormone receptor 1-like K04320 MCHR1; melanin-concentrating hormone receptor 1
C Melanocortin
D 104346732 MC2R; LOW QUALITY PROTEIN: adrenocorticotropic hormone receptor K04200 MC2R; melanocortin 2 receptor
D 104350227 MC3R; melanocortin receptor 3 K04201 MC3R; melanocortin 3 receptor
D 104341588 MC4R; melanocortin receptor 4 K04202 MC4R; melanocortin 4 receptor
D 104353500 MC5R; melanocortin receptor 5 K04203 MC5R; melanocortin 5 receptor
C Motilin
C Neuromedin U
D 104350200 NMUR1; neuromedin-U receptor 1 K05052 NMUR1; neuromedin U receptor 1
D 104349038 NMUR2; neuromedin-U receptor 2 K05053 NMUR2; neuromedin U receptor 2
C Neuropeptide FF
D 104343552 NPFFR1; neuropeptide FF receptor 1 K04240 NPFFR1; neuropeptide FF receptor 1
D 104344222 NPFFR2; neuropeptide FF receptor 2 K08375 NPFFR2; neuropeptide FF receptor 2
C Neuropeptide S
D 104350822 NPSR1; LOW QUALITY PROTEIN: neuropeptide S receptor K08376 NPSR1; neuropeptide S receptor
C Neuropeptide W / neuropeptide B
D 104344025 NPBWR1; neuropeptides B/W receptor type 1 K05268 NPBWR1; neuropeptides B/W receptor 1
D 104344288 NPBWR2; neuropeptides B/W receptor type 2 K08377 NPBWR2; neuropeptides B/W receptor 2
C Neuropeptide Y
D 104349042 NPY1R; neuropeptide Y receptor type 1 K04204 NPY1R; neuropeptide Y receptor type 1
D 104352277 NPY2R; neuropeptide Y receptor type 2 K04205 NPY2R; neuropeptide Y receptor type 2
D 104349895 neuropeptide Y receptor type 2-like K04205 NPY2R; neuropeptide Y receptor type 2
D 104350077 neuropeptide Y receptor type 4-like K04206 NPY4R; neuropeptide Y receptor type 4
D 104349063 NPY5R; neuropeptide Y receptor type 5 K04207 NPY5R; neuropeptide Y receptor type 5
D 104348067 neuropeptide Y receptor type 6-like K04208 NPY6R; neuropeptide Y receptor type 6
D 104343916 probable G-protein coupled receptor 83 K04210 GPR83; G protein-coupled receptor 83
D 104354629 probable G-protein coupled receptor 83 K04210 GPR83; G protein-coupled receptor 83
D 104350237 LOW QUALITY PROTEIN: probable G-protein coupled receptor 83 K04210 GPR83; G protein-coupled receptor 83
C Neurotensin
D 104345543 NTSR1; neurotensin receptor type 1 K04211 NTSR1; neurotensin receptor 1
C Opioid
D 104348128 OPRD1; delta-type opioid receptor K04213 OPRD1; delta-type opioid receptor
D 104347537 OPRK1; kappa-type opioid receptor K04214 OPRK1; kappa-type opioid receptor
D 104350921 OPRM1; mu-type opioid receptor K04215 OPRM1; mu-type opioid receptor
D 104346235 OPRL1; nociceptin receptor K04216 OPRL1; nociceptin receptor
C Orexigenic neuropeptide QRFP
D 104352192 QRFPR; pyroglutamylated RFamide peptide receptor K08378 QRFPR; pyroglutamylated RFamide peptide receptor
C Orexin
D 104352308 orexin receptor type 2-like K04239 HCRTR2; hypocretin (orexin) receptor 2
C Oxytocin
D 104349838 OXTR; oxytocin receptor K04229 OXTR; oxytocin receptor
C Prokineticin
D 104354475 prokineticin receptor 2 K08380 PROKR2; prokineticin receptor 2
C Prolactin-releasing peptide (PrRP)
D 104348165 prolactin-releasing peptide receptor-like K04314 PRLHR; prolactin releasing hormone receptor
D 104354081 PRLHR; prolactin-releasing peptide receptor K04314 PRLHR; prolactin releasing hormone receptor
D 104345317 prolactin-releasing peptide receptor-like K04314 PRLHR; prolactin releasing hormone receptor
C Prosaposin
D 104353507 GPR37L1; prosaposin receptor GPR37L1 K04244 GPR37L1; prosaposin receptor
C Relaxin
D 104340585 RXFP1; relaxin receptor 1 K04306 RXFP1; relaxin family peptide receptor 1
D 104349307 LOW QUALITY PROTEIN: relaxin receptor 2-like K04307 RXFP2; relaxin family peptide receptor 2
D 104349611 relaxin receptor 1-like K04307 RXFP2; relaxin family peptide receptor 2
D 104341496 RXFP3; relaxin-3 receptor 1 K08397 RXFP3; relaxin family peptide receptor 3
C Somatostatin
D 104353336 SSTR1; somatostatin receptor type 1 K04217 SSTR1; somatostatin receptor 1
D 104342212 SSTR2; somatostatin receptor type 2 K04218 SSTR2; somatostatin receptor 2
D 104342205 SSTR3; somatostatin receptor type 3 K04219 SSTR3; somatostatin receptor 3
D 104347439 SSTR4; somatostatin receptor type 4 K04220 SSTR4; somatostatin receptor 4
D 104348201 SSTR5; somatostatin receptor type 5 K04221 SSTR5; somatostatin receptor 5
C Tachykinin
D 104349582 TACR1; substance-P receptor K04222 TACR1; tachykinin receptor 1
D 104341200 TACR2; substance-K receptor K04223 TACR2; tachykinin receptor 2
D 104347033 TACR3; neuromedin-K receptor K04224 TACR3; tachykinin receptor 3
C Thrombin
D 104346214 F2R; proteinase-activated receptor 1 K03914 F2R; coagulation factor II (thrombin) receptor
D 104345518 F2RL1; proteinase-activated receptor 2 K04234 F2RL1; coagulation factor II (thrombin) receptor-like 1
D 104345500 F2RL2; proteinase-activated receptor 3 K04235 F2RL2; coagulation factor II (thrombin) receptor-like 2
D 104342669 F2RL3; proteinase-activated receptor 4 K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
C Thyrotropin
D 104347836 TSHR; thyrotropin receptor K04249 TSHR; thyrotropin receptor
C Thyrotropin-releasing hormone (TRH)
D 104341934 thyrotropin-releasing hormone receptor-like K04282 TRHR; thyrotropin-releasing hormone receptor
D 104350074 TRHR; thyrotropin-releasing hormone receptor K04282 TRHR; thyrotropin-releasing hormone receptor
C Urotensin II
D 104351344 LOW QUALITY PROTEIN: urotensin-2 receptor-like K04241 UTS2R; urotensin 2 receptor
D 104343359 UTS2R; urotensin-2 receptor K04241 UTS2R; urotensin 2 receptor
D 104354811 urotensin-2 receptor-like K04241 UTS2R; urotensin 2 receptor
D 104341960 urotensin-2 receptor-like K04241 UTS2R; urotensin 2 receptor
C Vasopressin
D 104343230 AVPR1B; vasopressin V1b receptor K04227 AVPR1B; arginine vasopressin receptor 1B
D 104345886 [Arg8]-vasotocin receptor-like K04228 AVPR2; arginine vasopressin receptor 2
C Neuropeptide receptors
B Chemokine
C CC Chemokine
D 104351452 CCR4; C-C chemokine receptor type 4 K04179 CCR4; C-C chemokine receptor type 4
D 104347166 C-C chemokine receptor type 5-like K04180 CCR5; C-C chemokine receptor type 5
D 104342547 CCR6; C-C chemokine receptor type 6 K04181 CCR6; C-C chemokine receptor type 6
D 104343986 CCR7; C-C chemokine receptor type 7 K04182 CCR7; C-C chemokine receptor type 7
D 104351455 CCR8; C-C chemokine receptor type 8 K04183 CCR8; C-C chemokine receptor type 8
D 104348888 C-C chemokine receptor type 8-like K04183 CCR8; C-C chemokine receptor type 8
D 104354458 CCR9; LOW QUALITY PROTEIN: C-C chemokine receptor type 9 K04184 CCR9; C-C chemokine receptor type 9
D 104352647 ACKR2; LOW QUALITY PROTEIN: atypical chemokine receptor 2 K04187 ACKR2; atypical chemokine receptor 2
D 104345967 ACKR4; atypical chemokine receptor 4 K04186 ACKR4; atypical chemokine receptor 4
D 104348212 GPR75; LOW QUALITY PROTEIN: probable G-protein coupled receptor 75 K08417 GPR75; G protein-coupled receptor 75
C CXC Chemokine
D 104354332 C-X-C chemokine receptor type 2-like K05050 CXCR2; C-X-C chemokine receptor type 2
D 104353098 CXCR4; C-X-C chemokine receptor type 4 K04189 CXCR4; C-X-C chemokine receptor type 4
D 104351630 CXCR5; C-X-C chemokine receptor type 5 K04190 CXCR5; C-X-C chemokine receptor type 5
D 104354455 CXCR6; C-X-C chemokine receptor type 6 K04191 CXCR6; C-X-C chemokine receptor type 6
D 104352833 ACKR3; atypical chemokine receptor 3 K04304 CXCR7; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
D 104349936 LOW QUALITY PROTEIN: G-protein coupled receptor 35-like K04276 CXCR8; C-X-C chemokine receptor type 8
D 104349937 G-protein coupled receptor 35-like K04276 CXCR8; C-X-C chemokine receptor type 8
D 104349938 G-protein coupled receptor 35-like K04276 CXCR8; C-X-C chemokine receptor type 8
C CX3C Chemokine
D 104351453 CX3CR1; CX3C chemokine receptor 1 K04192 CX3CR1; CX3C chemokine receptor 1
C C Chemokine
D 104348887 XCR1; chemokine XC receptor 1 K04193 XCR1; XC chemokine receptor 1
C Chemokine like
D 104345852 CMKLR1; chemokine-like receptor 1 K04245 CMKLR1; chemokine-like receptor 1
D 104340477 chemokine-like receptor 1 K04245 CMKLR1; chemokine-like receptor 1
D 104353619 GPR1; G-protein coupled receptor 1 K04310 GPR1; G protein-coupled receptor 1
D 104349261 GPR15; G-protein coupled receptor 15 K08403 GPR15; G protein-coupled receptor 15
B Base and nucleoside
C Purine / pyrimidine
D 104345608 P2RY1; P2Y purinoceptor 1 K04270 P2RY1; P2Y purinoceptor 1
D 104346806 P2Y purinoceptor 1-like K04270 P2RY1; P2Y purinoceptor 1
D 104345109 P2Y purinoceptor 2-like K04269 P2RY2; P2Y purinoceptor 2
D 104353993 P2RY4; P2Y purinoceptor 4 K04271 P2RY4; P2Y purinoceptor 4
D 104349579 P2RY6; P2Y purinoceptor 6 K04272 P2RY6; P2Y purinoceptor 6
D 104349835 P2RY8; P2Y purinoceptor 8 K08386 P2RY8; P2Y purinoceptor 8
D 104349188 P2RY12; P2Y purinoceptor 12 K04298 P2RY12; P2Y purinoceptor 12
D 104349192 P2RY13; LOW QUALITY PROTEIN: P2Y purinoceptor 13 K08388 P2RY13; P2Y purinoceptor 13
D 104349187 P2RY14; P2Y purinoceptor 14 K04299 P2RY14; P2Y purinoceptor 14
D 104352628 SUCNR1; succinate receptor 1 K10042 SUCNR1; succinate receptor 1
C Adenosine
D 104346356 ADORA1; adenosine receptor A1 K04265 ADORA1; adenosine receptor A1
D 104353374 adenosine receptor A2a-like K04266 ADORA2A; adenosine receptor A2a
D 104345628 ADORA3; LOW QUALITY PROTEIN: adenosine receptor A3 K04268 ADORA3; adenosine receptor A3
D 104345629 adenosine receptor A3-like K04268 ADORA3; adenosine receptor A3
B Lipid
C Arachidonylglycine
D 104345522 GPR18; N-arachidonyl glycine receptor K08410 GPR18; N-arachidonyl glycine receptor
C Bile acid
C Cysteinyl leukotriene
D 104350643 CYSLTR1; cysteinyl leukotriene receptor 1 K04322 CYSLTR1; cysteinyl leukotriene receptor 1
D 104354874 CYSLTR2; cysteinyl leukotriene receptor 2 K04323 CYSLTR2; cysteinyl leukotriene receptor 2
C Free fatty acid
C HETE and oxoETE
C Leukotriene
D 104341950 LOW QUALITY PROTEIN: leukotriene B4 receptor 1-like K04296 LTB4R1; leukotriene B4 receptor 1
C Lysophosphatidic acid
D 104343105 LPAR1; lysophosphatidic acid receptor 1 isoform X1 K04289 LPAR1; lysophosphatidic acid receptor 1
D 104341866 LPAR2; lysophosphatidic acid receptor 2 K04291 LPAR2; lysophosphatidic acid receptor 2
D 104348404 LPAR3; lysophosphatidic acid receptor 3 K04294 LPAR3; lysophosphatidic acid receptor 3
D 104346740 LPAR4; lysophosphatidic acid receptor 4 K04275 LPAR4; lysophosphatidic acid receptor 4
D 104345240 lysophosphatidic acid receptor 5-like K08390 LPAR5; lysophosphatidic acid receptor 5
D 104346657 lysophosphatidic acid receptor 6-like K04273 LPAR6; lysophosphatidic acid receptor 6
D 104341773 LPAR6; lysophosphatidic acid receptor 6 K04273 LPAR6; lysophosphatidic acid receptor 6
D 104349191 GPR87; G-protein coupled receptor 87 K08389 GPR87; G protein-coupled receptor 87
C Lysophosphatidylinositol
D 104345330 GPR55; G-protein coupled receptor 55 K08413 GPR55; G protein-coupled receptor 55
C Lysophosphatidylserine
D 104351554 GPR34; probable G-protein coupled receptor 34 K08383 GPR34; G protein-coupled receptor 34
D 104352128 putative P2Y purinoceptor 10 K04274 P2RY10; P2Y purinoceptor 10
D 104352130 putative P2Y purinoceptor 10 K04274 P2RY10; P2Y purinoceptor 10
D 104352129 GPR174; probable G-protein coupled receptor 174 K08391 GPR174; G protein-coupled receptor 174
C Oleoylethanolamide
D 104340028 GPR119; glucose-dependent insulinotropic receptor K08424 GPR119; glucose-dependent insulinotropic receptor
C Prostaglandin
D 104348078 prostaglandin E2 receptor EP2 subtype-like K04259 PTGER2; prostaglandin E receptor 2
D 104345545 PTGER3; prostaglandin E2 receptor EP3 subtype K04260 PTGER3; prostaglandin E receptor 3
D 104349349 LOW QUALITY PROTEIN: prostaglandin F2-alpha receptor-like K04262 PTGFR; prostaglandin F receptor
C Prostacyclin
C Sphingolipid
D 104353540 S1PR1; sphingosine 1-phosphate receptor 1 K04288 S1PR1; sphingosine 1-phosphate receptor 1
D 104352398 S1PR2; sphingosine 1-phosphate receptor 2 K04292 S1PR2; sphingosine 1-phosphate receptor 2
D 104343227 S1PR3; sphingosine 1-phosphate receptor 3 K04290 S1PR3; sphingosine 1-phosphate receptor 3
D 104344241 S1PR4; sphingosine 1-phosphate receptor 4 K04293 S1PR4; sphingosine 1-phosphate receptor 4
C Thromboxane
D 104341458 TBXA2R; thromboxane A2 receptor K04264 TBXA2R; thromboxane A2 receptor
B Vision
C Opsin
D 104353026 green-sensitive opsin K04250 RHO; rhodopsin
D 104344853 RHO; rhodopsin K04250 RHO; rhodopsin
D 104354580 LOW QUALITY PROTEIN: pinopsin-like K04251 OPN1LW; long/medium wavelength-sensitive opsin
D 104346918 opsin-3-like K04256 OPN3; c-opsin
D 104342385 opsin-VA-like K04256 OPN3; c-opsin
D 104341549 pinopsin-like K04256 OPN3; c-opsin
D 104353968 melanopsin-A-like K04255 OPN4; r-opsin
D 104344724 melanopsin-like K04255 OPN4; r-opsin
D 104346016 opsin-5-like K08385 OPN5; G0-opsin
D 104344040 OPN5; opsin-5 K08385 OPN5; G0-opsin
D 104354840 RRH; visual pigment-like receptor peropsin K04253 RRH; visual pigment-like receptor peropsin
D 104347209 RGR; RPE-retinal G protein-coupled receptor K04254 RGR; retinal G protein coupled receptor
B Others
C Alpha-ketoglutarate
D 104353725 LOW QUALITY PROTEIN: 2-oxoglutarate receptor 1-like K08419 OXGR1; oxoglutarate (alpha-ketoglutarate) receptor 1
D 104344152 2-oxoglutarate receptor 1-like K08419 OXGR1; oxoglutarate (alpha-ketoglutarate) receptor 1
C Cannabinoid
D 104342281 CNR1; cannabinoid receptor 1 isoform X1 K04277 CNR1; cannabinoid receptor 1
D 104343183 CNR2; cannabinoid receptor 2 K04278 CNR2; cannabinoid receptor 2
C Estrogen
D 104345895 GPER1; G-protein coupled estrogen receptor 1 K04246 GPER1; G-protein coupled estrogen receptor 1
C Hydroxy-carboxylic acid
C L-Tryptophan and L-Phenylalanine
D 104347527 GPR139; probable G-protein coupled receptor 139 K08428 GPR139; G protein-coupled receptor 139
D 104344647 GPR142; LOW QUALITY PROTEIN: probable G-protein coupled receptor 142 K08430 GPR142; G protein-coupled receptor 142
C Mas proto-oncogene and Mas-related (MRGs)
D 104344553 MAS1; proto-oncogene Mas K04303 MAS1; proto-oncogene Mas
C Melatonin
D 104354493 MTNR1A; melatonin receptor type 1A K04285 MTNR1A; melatonin receptor type 1A
D 104354713 melatonin receptor type 1C K04285 MTNR1A; melatonin receptor type 1A
D 104341330 melatonin receptor type 1B K04286 MTNR1B; melatonin receptor type 1B
C Oxysterol
D 104348569 G-protein coupled receptor 183-like K04305 EBI2; Epstein-Barr virus induced gene 2
D 104353775 GPR183; G-protein coupled receptor 183 K04305 EBI2; Epstein-Barr virus induced gene 2
C Platelet activating factor
D 104340753 PTAFR; platelet-activating factor receptor K04279 PTAFR; platelet-activating factor receptor
C Proton-sensing GPCRs
D 104354037 GPR65; psychosine receptor K08416 GPR65; psychosine receptor
D 104354106 GPR68; ovarian cancer G-protein coupled receptor 1 K08408 GPR68; ovarian cancer G-protein coupled receptor 1
D 104351206 GPR132; probable G-protein coupled receptor 132 K08426 GPR132; G protein-coupled receptor 132
C R-spondin
D 104347591 LGR4; leucine-rich repeat-containing G-protein coupled receptor 4 K04309 LGR4; leucine-rich repeat-containing G protein-coupled receptor 4
D 104351955 LGR5; leucine-rich repeat-containing G-protein coupled receptor 5 K04308 LGR5; leucine-rich repeat-containing G protein-coupled receptor 5
D 104344052 LGR6; LOW QUALITY PROTEIN: leucine-rich repeat-containing G-protein coupled receptor 6 K08399 LGR6; leucine-rich repeat-containing G protein-coupled receptor 6
C Super conserved receptor expressed in brain (SREB)
D 104342282 GPR27; probable G-protein coupled receptor 27 K04301 SREB1; super conserved receptor expressed in brain 1
D 104347619 GPR85; probable G-protein coupled receptor 85 K04302 SREB2; super conserved receptor expressed in brain 2
C Trissin
C Orphan GPCRs / unclassified GPCRs
D 104349374 G-protein coupled receptor 12-like K04311 GPR3; G protein-coupled receptor 3
D 104344643 GPR6; G-protein coupled receptor 6 K04313 GPR6; G protein-coupled receptor 6
D 104345783 GPR12; G-protein coupled receptor 12 K04315 GPR12; G protein-coupled receptor 12
D 104339997 G-protein coupled receptor 12-like K04315 GPR12; G protein-coupled receptor 12
D 104351062 GPR17; uracil nucleotide/cysteinyl leukotriene receptor K08404 GPR17; G protein-coupled receptor 17
D 104342093 GPR20; G-protein coupled receptor 20 K04317 GPR20; G protein-coupled receptor 20
D 104342333 GPR21; probable G-protein coupled receptor 21 K04318 GPR21; G protein-coupled receptor 21
D 104346963 GPR22; probable G-protein coupled receptor 22 K04319 GPR22; G protein-coupled receptor 22
D 104345328 GPR25; probable G-protein coupled receptor 25 K08405 GPR25; G protein-coupled receptor 25
D 104340053 G-protein coupled receptor 26-like K08411 GPR26; G protein-coupled receptor 26
D 104354405 GPR26; G-protein coupled receptor 26 K08411 GPR26; G protein-coupled receptor 26
D 104348068 G-protein coupled receptor 39-like K08412 GPR39; G protein-coupled receptor 39
D 104352458 GPR52; probable G-protein coupled receptor 52 K08407 GPR52; G protein-coupled receptor 52
D 104344254 GPR61; probable G-protein coupled receptor 61 K08414 GPR61; G protein-coupled receptor 61
D 104343664 GPR63; probable G-protein coupled receptor 63 K04321 GPR63; G protein-coupled receptor 63
D 104340474 GPR82; probable G-protein coupled receptor 82 K08420 GPR82; G protein-coupled receptor 82
D 104351900 GPR88; probable G-protein coupled receptor 88 K08422 GPR88; G protein-coupled receptor 88
D 104347059 LOW QUALITY PROTEIN: probable G-protein coupled receptor 141 K08429 GPR141; G protein-coupled receptor 141
D 104340376 GPR146; probable G-protein coupled receptor 146 K08431 GPR146; G protein-coupled receptor 146
D 104348095 GPR148; LOW QUALITY PROTEIN: probable G-protein coupled receptor 148 K08432 GPR148; G protein-coupled receptor 148
D 104353770 GPR149; probable G-protein coupled receptor 149 K08433 GPR149; G protein-coupled receptor 149
D 104343442 GPR160; probable G-protein coupled receptor 160 K08438 GPR160; G protein-coupled receptor 160
D 104339934 GPR161; G-protein coupled receptor 161 K08439 GPR161; G protein-coupled receptor 161
D 104341363 GPR162; probable G-protein coupled receptor 162 K08440 GPR162; G protein-coupled receptor 162
D 104352736 GPR176; probable G-protein coupled receptor 176 K08442 GPR176; G protein-coupled receptor 176
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ASecretin receptor family
B Calcium-regulating peptide
C Calcitonin
D 104351291 calcitonin receptor-like K04576 CALCR; calcitonin receptor
D 104349853 CALCRL; calcitonin gene-related peptide type 1 receptor K04577 CALCRL; calcitonin receptor-like
C Parathyroid hormone
D 104352894 parathyroid hormone/parathyroid hormone-related peptide receptor K04585 PTH1R; parathyroid hormone receptor 1
D 104353454 LOW QUALITY PROTEIN: parathyroid hormone/parathyroid hormone-related peptide receptor-like K04585 PTH1R; parathyroid hormone receptor 1
B Hypothalamic hormone
C Corticotropin-releasing hormone (CRH)
D 104341018 corticotropin-releasing factor receptor 1 K04578 CRHR1; corticotropin releasing hormone receptor 1
C Growth hormone-releasing hormone (GHRH)
D 104351840 GHRHR; LOW QUALITY PROTEIN: growth hormone-releasing hormone receptor K04584 GHRHR; growth hormone releasing hormone receptor
B Pancreatic peptide
C Glucagon
D 104354503 GLP1R; glucagon-like peptide 1 receptor K04581 GLP1R; glucagon-like peptide 1 receptor
D 104340932 GLP2R; glucagon-like peptide 2 receptor K04582 GLP2R; glucagon-like peptide 2 receptor
D 104346134 glucagon receptor-like K04583 GCGR; glucagon receptor
D 104349260 GCGR; glucagon receptor K04583 GCGR; glucagon receptor
B Gut peptide
C Gastric inhibitory peptide (GIP)
C Vasoactive intestinal polypeptide (VIP) and pituitary adenyl cyclase-activating peptide (PACAP)
D 104340583 vasoactive intestinal polypeptide receptor-like K04589 VIPR1; vasoactive intestinal peptide receptor 1
D 104353906 vasoactive intestinal polypeptide receptor 1-like K04589 VIPR1; vasoactive intestinal peptide receptor 1
D 104347305 VIPR2; vasoactive intestinal polypeptide receptor 2 K04590 VIPR2; vasoactive intestinal peptide receptor 2
D 104342475 pituitary adenylate cyclase-activating polypeptide type I receptor-like K04587 ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor
C Secretin
D 104340925 SCTR; secretin receptor K04588 SCTR; secretin receptor
B Others
C Receptor activity modifying protein
D 104342642 receptor activity-modifying protein 1-like K08447 RAMP1; receptor activity modifying protein 1
D 104352797 RAMP2; receptor activity-modifying protein 2 K08448 RAMP2; receptor activity modifying protein 2
D 104354010 RAMP3; receptor activity-modifying protein 3 K08449 RAMP3; receptor activity modifying protein 3
C Methuselah-like proteins (MTH)
C Pigment dispersing factor (PDF)
#
AAdhesion receptor family
B Cadherin EGF LAG (CELSR)
C 104354950 LOW QUALITY PROTEIN: cadherin EGF LAG seven-pass G-type receptor 3-like K04602 CELSR3; cadherin EGF LAG seven-pass G-type receptor 3
B EGF-like module-containing mucin-like hormone receptor-like (EMR)
B Latrophilin
C 104347702 LPHN2; latrophilin-2 K04593 ADGRL2; adhesion G protein-coupled receptor L2
C 104346853 LPHN3; latrophilin-3 K04594 ADGRL3; adhesion G protein-coupled receptor L3
C 104344748 ELTD1; EGF, latrophilin and seven transmembrane domain-containing protein 1 K04595 ADGRL4; adhesion G protein-coupled receptor L4
B Brain-specific angiogenesis inhibitor (BAI)
B Others
C 104352288 probable G-protein coupled receptor 125 K08460 ADGRA1; adhesion G protein-coupled receptor A1
C 104345691 GPR125; probable G-protein coupled receptor 125 K08462 ADGRA3; adhesion G protein-coupled receptor A3
C 104351968 GPR133; probable G-protein coupled receptor 133 K08465 ADGRD1; adhesion G-protein coupled receptor D1
C 104351633 GPR144; probable G-protein coupled receptor 144 K08466 ADGRD2; adhesion G-protein coupled receptor D2
C 104354038 LOW QUALITY PROTEIN: probable G-protein coupled receptor 115 K08457 ADGRF4; adhesion G-protein coupled receptor F4
C 104340916 GPR116; probable G-protein coupled receptor 116 K08458 ADGRF5; adhesion G-protein coupled receptor F5
C 104339783 GPR56; G-protein coupled receptor 56 K08450 ADGRG1; adhesion G-protein coupled receptor G1
C 104347974 G-protein coupled receptor 64-like K08451 ADGRG2; adhesion G-protein coupled receptor G2
C 104342249 GPR97; LOW QUALITY PROTEIN: probable G-protein coupled receptor 97 K08452 ADGRG3; adhesion G-protein coupled receptor G3
C 104350893 GPR114; LOW QUALITY PROTEIN: probable G-protein coupled receptor 114 K08459 ADGRG5; adhesion G-protein coupled receptor G5
C 104340492 GPR128; probable G-protein coupled receptor 128 K08464 ADGRG7; adhesion G-protein coupled receptor G7
C 104348711 GPR98; LOW QUALITY PROTEIN: G-protein coupled receptor 98 K18263 ADGRV1; adhesion G-protein coupled receptor V1
#
AMetabotropic glutamate receptor family
B Glutamate (metabotropic)
C 104346684 GRM1; metabotropic glutamate receptor 1 K04603 GRM1; metabotropic glutamate receptor 1
C 104353478 metabotropic glutamate receptor 2-like K04605 GRM2; metabotropic glutamate receptor 2
C 104343719 metabotropic glutamate receptor 3 K04606 GRM3; metabotropic glutamate receptor 3
C 104351833 GRM4; metabotropic glutamate receptor 4 K04607 GRM4; metabotropic glutamate receptor 4
C 104354717 GRM5; metabotropic glutamate receptor 5 K04604 GRM5; metabotropic glutamate receptor 5
C 104345825 GRM7; metabotropic glutamate receptor 7 K04609 GRM7; metabotropic glutamate receptor 7
C 104347948 GRM8; metabotropic glutamate receptor 8 K04610 GRM8; metabotropic glutamate receptor 8
B GABA
C 104347752 GPR156; LOW QUALITY PROTEIN: probable G-protein coupled receptor 156 K04617 GPR156; gamma-aminobutyric acid type B receptor-like
B Calcium-sensing
C 104345105 CASR; extracellular calcium-sensing receptor K04612 CASR; calcium-sensing receptor
C 104352499 GPRC6A; LOW QUALITY PROTEIN: G-protein coupled receptor family C group 6 member A K04622 GPRC6A; G protein-coupled receptor family C group 6 member A
B Orphan GPRC5
C 104349956 retinoic acid-induced protein 3-like K08468 GPRC5A; G protein-coupled receptor family C group 5 member A
C 104354016 GPRC5B; G-protein coupled receptor family C group 5 member B K04619 GPRC5B; G protein-coupled receptor family C group 5 member B
C 104342484 GPRC5C; G-protein coupled receptor family C group 5 member C K04620 GPRC5C; G protein-coupled receptor family C group 5 member C
B Unclassified GPCRs
C 104353869 GPR158; probable G-protein coupled receptor 158 K08469 GPR158; G protein-coupled receptor 158
#
AFrizzled / Smoothened family
B 104346449 frizzled-1 K02432 FZD1_7; frizzled 1/7
B 104353197 LOW QUALITY PROTEIN: frizzled-7-like K02432 FZD1_7; frizzled 1/7
B 104340206 FZD2; frizzled-2 K02235 FZD2; frizzled 2
B 104342378 FZD3; frizzled-3 K02329 FZD3; frizzled 3
B 104346763 FZD4; frizzled-4 K02354 FZD4; frizzled 4
B 104349520 LOW QUALITY PROTEIN: frizzled-5-like K02375 FZD5_8; frizzled 5/8
B 104342236 FZD6; frizzled-6 K02376 FZD6; frizzled 6
B 104342359 FZD10; frizzled-10 K02842 FZD9_10; frizzled 9/10
B 104340538 FZD9; frizzled-9 K02842 FZD9_10; frizzled 9/10
B 104348844 SMO; smoothened homolog K06226 SMO; smoothened
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AOthers
B Chemoreception
C Olfactory
D 104346042 olfactory receptor 10A7-like K04257 OLFR; olfactory receptor
D 104346250 olfactory receptor 52B2-like K04257 OLFR; olfactory receptor
D 104340626 olfactory receptor 4Q2-like K04257 OLFR; olfactory receptor
D 104339909 olfactory receptor 5V1-like K04257 OLFR; olfactory receptor
D 104340579 LOW QUALITY PROTEIN: olfactory receptor 4S2-like K04257 OLFR; olfactory receptor
D 104341992 olfactory receptor 4S2-like K04257 OLFR; olfactory receptor
D 104352327 olfactory receptor 5AS1-like K04257 OLFR; olfactory receptor
D 104352329 LOW QUALITY PROTEIN: olfactory receptor 8D1-like K04257 OLFR; olfactory receptor
D 104352330 olfactory receptor 2D3-like K04257 OLFR; olfactory receptor
D 104342329 LOW QUALITY PROTEIN: olfactory receptor 14A16-like K04257 OLFR; olfactory receptor
D 104340744 olfactory receptor 14C36-like K04257 OLFR; olfactory receptor
D 104347269 olfactory receptor 1020-like K04257 OLFR; olfactory receptor
D 104347280 olfactory receptor 1052-like K04257 OLFR; olfactory receptor
D 104347291 olfactory receptor 5B21-like K04257 OLFR; olfactory receptor
D 104347298 LOW QUALITY PROTEIN: olfactory receptor 1013 K04257 OLFR; olfactory receptor
D 104347308 olfactory receptor 1009-like K04257 OLFR; olfactory receptor
D 104352570 olfactory receptor 52I2-like K04257 OLFR; olfactory receptor
D 104341368 olfactory receptor 52K2-like K04257 OLFR; olfactory receptor
D 104347590 olfactory receptor 51Q1-like K04257 OLFR; olfactory receptor
D 104340389 olfactory receptor 52R1-like K04257 OLFR; olfactory receptor
D 104347703 olfactory receptor 14J1-like K04257 OLFR; olfactory receptor
D 104347721 olfactory receptor 14A16-like K04257 OLFR; olfactory receptor
D 104341884 olfactory receptor 51G2-like K04257 OLFR; olfactory receptor
D 104343104 olfactory receptor 51L1-like K04257 OLFR; olfactory receptor
D 104340559 olfactory receptor 14C36-like K04257 OLFR; olfactory receptor
D 104348456 olfactory receptor 14J1-like K04257 OLFR; olfactory receptor
D 104353527 olfactory receptor 1F1-like K04257 OLFR; olfactory receptor
D 104340688 olfactory receptor 51E2-like K04257 OLFR; olfactory receptor
D 104340567 LOW QUALITY PROTEIN: olfactory receptor 11L1-like K04257 OLFR; olfactory receptor
D 104340692 olfactory receptor 52K2-like K04257 OLFR; olfactory receptor
D 104340701 olfactory receptor 2A12-like K04257 OLFR; olfactory receptor
D 104343675 LOW QUALITY PROTEIN: olfactory receptor 6C75-like K04257 OLFR; olfactory receptor
D 104343677 olfactory receptor 14J1-like K04257 OLFR; olfactory receptor
D 104340569 LOW QUALITY PROTEIN: olfactory receptor 14A16-like K04257 OLFR; olfactory receptor
D 104343976 putative olfactory receptor 10AC1 K04257 OLFR; olfactory receptor
D 104354265 olfactory receptor 52B2-like K04257 OLFR; olfactory receptor
D 104354266 olfactory receptor 52B2-like K04257 OLFR; olfactory receptor
D 104340214 olfactory receptor 14A16-like K04257 OLFR; olfactory receptor
D 104349720 LOW QUALITY PROTEIN: olfactory receptor 10C1 K04257 OLFR; olfactory receptor
D 104349808 olfactory receptor 8I2-like K04257 OLFR; olfactory receptor
D 104349809 olfactory receptor 1020-like K04257 OLFR; olfactory receptor
D 104354773 putative olfactory receptor 51H1 K04257 OLFR; olfactory receptor
D 104354774 olfactory receptor 51E2-like K04257 OLFR; olfactory receptor
D 104350217 LOW QUALITY PROTEIN: olfactory receptor 10A7-like K04257 OLFR; olfactory receptor
C Taste
D 104352625 taste receptor type 2 member 8-like K08474 TAS2R; taste receptor type 2
D 104340940 taste receptor type 2 member 9-like K08474 TAS2R; taste receptor type 2
C Vomeronasal pheromone
C Insect odorant and taste
C Nematode chemoreception
C Fungal mating pheromone
B Others
C Ocular albinism proteins
D 104345087 GPR143; G-protein coupled receptor 143 K08470 OA1; ocular albinism type 1 protein
C Neuronostatin
D 104342343 LOW QUALITY PROTEIN: protein GPR107-like K22985 GPR107; G protein-coupled receptor 107
C Plant Mlo receptors
C cAMP signaling
C Bacterial rhodopsin
C Orphan GPCRs
D 104350255 TPRA1; LOW QUALITY PROTEIN: transmembrane protein adipocyte-associated 1 K22988 TPRA1; transmembrane protein adipocyte-associated 1
D 104341253 GPR137B; integral membrane protein GPR137B isoform X1 K22989 GPR137; integral membrane protein GPR137
D 104340982 GPR137C; integral membrane protein GPR137C K22989 GPR137; integral membrane protein GPR137
D 104342441 GPR157; probable G-protein coupled receptor 157 K08467 GPR157; G protein-coupled receptor 157
!
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 8, 2022
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Classification taken and modified from GPCRDB