+F Repair protein KO
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DNA Repair and Recombination Proteins - Lysobacter gummosus
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D LG3211_1393 methylated-DNA-[]-cysteine S-methyltransferase family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D LG3211_2628 FAD binding domain of DNA photolyase family protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E LG3211_5004 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LG3211_3479 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LG3211_3278 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
D LG3211_0996 S1/P1 Nuclease family protein K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D LG3211_4065 mutator mutT family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LG3211_1476 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LG3211_4174 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LG3211_2687 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LG3211_0442 dut; dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D LG3211_1393 methylated-DNA-[]-cysteine S-methyltransferase family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D LG3211_4428 methylated-DNA-[]-cysteine S-methyltransferase family protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D LG3211_2628 FAD binding domain of DNA photolyase family protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E LG3211_5004 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LG3211_2195 DNA-deoxyinosine glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E LG3211_1607 hhH-GPD superbase excision DNA repair family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E LG3211_1394 alkA N-terminal domain protein K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E LG3211_3479 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LG3211_1221 methyladenine glycosylase family protein K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E LG3211_5145 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E LG3211_3278 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E LG3211_5103 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E LG3211_0448 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E LG3211_2319 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E LG3211_2751 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E LG3211_5028 polA; DNA polymerase I family protein K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E LG3211_3266 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E LG3211_3547 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E LG3211_3038 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E LG3211_5035 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LG3211_5028 polA; DNA polymerase I family protein K02335 polA; DNA polymerase I [EC:2.7.7.7]
E LG3211_2751 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F LG3211_3770 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F LG3211_3769 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F LG3211_3739 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F LG3211_0956 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F LG3211_1647 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E LG3211_3219 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E LG3211_3158 mutL; DNA mismatch repair MutL family protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E LG3211_2674 exonuclease family protein K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E LG3211_1782 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E LG3211_3340 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E LG3211_3336 DNA polymerase III, &alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E LG3211_0002 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E LG3211_4136 DNA polymerase III chi subunit, HolC family protein K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E LG3211_3378 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E LG3211_1743 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E LG3211_1695 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E LG3211_1719 dnaX; DNA polymerase III, subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E LG3211_2751 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E LG3211_5035 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LG3211_3679 ssb; single-stranded DNA-binding family protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E LG3211_0092 recB; exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E LG3211_0091 recC; exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E LG3211_0093 recD; exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E LG3211_3196 recA; protein RecA K03553 recA; recombination protein RecA
E LG3211_3994 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E LG3211_3990 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E LG3211_3995 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E LG3211_4959 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E LG3211_2674 exonuclease family protein K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
D RecFOR pathway proteins
E LG3211_3196 recA; protein RecA K03553 recA; recombination protein RecA
E LG3211_3245 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E LG3211_0003 recF; DNA replication and repair RecF family protein K03629 recF; DNA replication and repair protein RecF
E LG3211_0964 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E LG3211_2319 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E LG3211_1755 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E LG3211_1722 recR; recombination protein RecR K06187 recR; recombination protein RecR
E LG3211_2302 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E LG3211_5173 exonuclease, RdgC family protein K03554 rdgC; recombination associated protein RdgC
E LG3211_3994 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E LG3211_3990 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E LG3211_3995 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E LG3211_2172 putative ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E LG3211_2415 ku protein K10979 ku; DNA end-binding protein Ku
E LG3211_2416 ligD; DNA ligase D K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F LG3211_2745 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F LG3211_0004 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F LG3211_4944 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F LG3211_5213 eukaryotic DNA topoisomerase I, catalytic core family protein K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F LG3211_3361 bacterial DNA-binding family protein K03530 hupB; DNA-binding protein HU-beta
F LG3211_4401 hypothetical protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F LG3211_2319 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F LG3211_1755 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F LG3211_1722 recR; recombination protein RecR K06187 recR; recombination protein RecR
F LG3211_2751 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F LG3211_0810 bacterial regulatory, Fis family protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F LG3211_3532 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
F LG3211_2911 ihfB; integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F LG3211_2674 exonuclease family protein K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F LG3211_3964 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F LG3211_3266 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F LG3211_3547 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F LG3211_4147 H-NS histone family protein K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D LG3211_0043 impB/mucB/samB family protein K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D LG3211_0930 impB/mucB/samB family protein K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D LG3211_3196 recA; protein RecA K03553 recA; recombination protein RecA
D LG3211_3198 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D LG3211_2254 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D LG3211_2302 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D LG3211_2252 impB/mucB/samB family protein K14161 imuB; protein ImuB
D LG3211_2251 dnaE; DNA polymerase III, alpha subunit K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D LG3211_3679 ssb; single-stranded DNA-binding family protein K03111 ssb; single-strand DNA-binding protein
D LG3211_3195 recX; regulatory recX domain protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D LG3211_5197 uvrD/REP helicase N-terminal domain protein K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D LG3211_3948 DEAD/DEAH box helicase family protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D LG3211_2411 DEAD/DEAH box helicase family protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D LG3211_4065 mutator mutT family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LG3211_1476 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LG3211_4174 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LG3211_2687 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LG3211_0442 dut; dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D LG3211_1009 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D LG3211_4402 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D LG3211_2281 ribonucleotide reductase, barrel domain protein K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D LG3211_1008 ribonucleotide reductase, small chain family protein K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024