+E	Transcription factors	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Transcription Factors - Leishmania major</h2>
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A<b>Eukaryotic type</b>
B  Basic leucine zipper (bZIP)
C    AP-1(-like) components, Jun
C    AP-1(-like) components, Fos
C    AP-1(-like) components, Maf
C    AP-1(-like) components, NF-E2
C    AP-1(-like) components, Fungal regulators
C    AP-1(-like) components, CRE-BP/ATF
C    CREB
C    C/EBP-like factors
C    bZIP/PAR
C    Plant bZIP factors
C    ZIP only
B  Basic helix-loop-helix (bHLH)
C    Ubiquitous (class A) factors
C    Myogenic transcription factors
C    Achaete-Scute
C    Tal/Twist/Atonal/Hen, Lymphoid factors
C    Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors
C    Tal/Twist/Atonal/Hen, HEN
C    Tal/Twist/Atonal/Hen, Mesp
C    Tal/Twist/Atonal/Hen, Atonal
C    Tal/Twist/Atonal/Hen, Pancreatic factors
C    Hairy, Hairy/E(SPL)
C    Hairy, Fungal regulators
C    Factors with PAS domain
C    Yabby
C    INO
C    HLH domain only
B  Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
C    Ubiquitous bHLH-ZIP factors
C    Cell cycle controlling factors, Myc
C    Cell cycle controlling factors, Mad/Max
C    Other bHLH-ZIP factors
B  Other basic domains
C    NF-1
C    RF-X
C    AP-2 (bHSH)
B  Zinc finger
C    Cys4 thyroid hormone receptor-like
C    Cys4 hepatocyte nuclear factor 4-like
C    Cys4 estrogen receptor-like
C    Cys4 nerve growth factor IB-like
C    Cys4 Fushi tarazu-F1-like
C    Cys4 germ cell nuclear factor
C    Cys4 Knirps/DAX1-like
C    Cys4 GATA-factors
C    Cys2His2 SP/KLF family and related proteins
C    Cys2His2 GLI-like
C    Cys2His2 Snail
C    Cys2His2 BTB-ZF factors
C    Cys2His2 BED
C    Cys2His2 PRDM
C    Cys2His2 metabolic regulators in fungi
C    Cys2His2 others
D      LMJF_28_1820 RPA1; putative replication factor A, 51kDa subunit	K07466 RFA1; replication factor A1 
C    Cys2HisCys zinc factors
C    Cys3His zinc factors
C    Cys2CysHis zinc factors
C    CXXC CpG-binding proteins
D      LMJF_25_1200 modification methylase-like protein	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
C    Cys6 metabolic regulators in fungi
C    Other zinc fingers
D      LMJF_22_0060 transcription factor-like protein	K12236 NFX1; transcriptional repressor NF-X1 
D      LMJF_36_1640 HEXBP; putative universal minicircle sequence binding protein	K09250 CNBP; cellular nucleic acid-binding protein 
D      LMJF_36_1635 putative poly-zinc finger protein 2	K09250 CNBP; cellular nucleic acid-binding protein 
D      LMJF_36_1610 UMSBP1; putative universal minicircle sequence binding protein	K09250 CNBP; cellular nucleic acid-binding protein 
D      LMJF_36_1620 UMSBP2; universal minicircle sequence binding protein	K09250 CNBP; cellular nucleic acid-binding protein 
B  Helix-turn-helix
C    Homeo domain ANTP: HOXL
C    Homeo domain ANTP: NKL
C    Homeo domain Paired-related
C    Homeo domain LIM
C    Homeo domain POU
C    Homeo domain SINE
C    Homeo domain ZF
C    Homeo domain CUT
C    Homeo domain PROS
C    Homeo domain TALE
C    Homeo domain other
C    Fork head/winged helix developmental regulators
C    Fork head/winged helix tissue-specific regulators
C    Fork head/winged helix cell cycle-controlling factors, E2F
C    Fork head/winged helix cell cycle-controlling factors, DP
C    Fork head/winged helix other regulators
C    Heat shock factors
C    Tryptophan clusters Myb, Myb-factors
C    Tryptophan clusters Myb, Myb-like factors
C    Tryptophan clusters Ets-type
C    Tryptophan clusters interferon-regulating factors
C    TEA domain
C    ARID
B  beta-Scaffold factors with minor groove contacts
C    RHR (Rel homology region) Rel/Ankyrin
C    RHR (Rel homology region) Ankyrin only
C    RHR (Rel homology region) NF-AT
C    STAT
C    p53
C    MADS-box regulators of differentiation, MEF-2
C    MADS-box regulators of differentiation, Homeotic genes
C    MADS-box regulators of differentiation, Yeast regulators
C    MADS-box responders to external signals
C    SAND domain-containing proteins
C    TATA-binding proteins
D      LMJF_19_1390 transcription initiation factor-like protein (TFIID-like protein)	K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein 
C    HMG SOX
C    HMG TCF-1
C    HMG2-related
D      LMJF_32_0210 hypothetical protein	K09272 SSRP1; FACT complex subunit SSRP1/POB3 
C    UBF
C    Other HMG box factors
C    Heteromeric CCAAT factors
C    Grainyhead
C    Cold-shock domain factors, DbpA-like
C    Cold-shock domain factors, YB-1/DbpB-like
C    Cold-shock domain factors, FRG Y2-like
C    Runt
C    MYRF
B  Other transcription factors
C    HMGI(Y)
C    NUPR
E        Line #4
C    Pocket domain Rb
C    Pocket domain CBP
C    T-box
C    DMRT
C    LRRFIP
C    TCP
C    AP2/ERF
C    WRKY
C    LOB
C    Copper-fist proteins fungal regulators
C    Others
D      LMJF_32_3730 hypothetical protein	K22145 TMEM18; transmembrane protein 18 
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A<b>Prokaryotic type</b>
B  Helix-turn-helix
C    AraC family
C    LysR family
C    DeoR family
C    LacI family
C    GntR family
C    TetR/AcrR family
C    Lrp/AsnC family
C    LuxR family
C    MarR family
C    MerR family
C    Fur family
C    IclR family
C    CRP/FNR family
C    Rrf2 family
C    ArsR family
C    XRE family
C    PadR family
C    Other families
D      LMJF_31_1070 biotin/lipoate protein ligase-like protein	K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] 
B  Ribbon-helix-helix
C    CopG family
C    Other families
B  Other transcription factors
C    BglG family
C    Others
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#Last updated: June 7, 2024
#<br>Classification taken and modified from <a href="http://www.gene-regulation.com/pub/databases.html#transfac">TRANSFAC 7.0</a>