+E Replication protein KO
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DNA Replication Proteins - Lactuca sativa (garden lettuce)
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
D 111899851 origin of replication complex subunit 1A K02603 ORC1; origin recognition complex subunit 1
D 111876197 origin of replication complex subunit 2 isoform X1 K02604 ORC2; origin recognition complex subunit 2
D 111921208 origin of replication complex subunit 3 isoform X1 K02605 ORC3; origin recognition complex subunit 3
D 111894287 origin of replication complex subunit 4 K02606 ORC4; origin recognition complex subunit 4
D 111902671 origin of replication complex subunit 5 K02607 ORC5; origin recognition complex subunit 5
D 111896106 origin of replication complex subunit 6 K02608 ORC6; origin recognition complex subunit 6
D 111921201 CDT1-like protein a, chloroplastic K10727 CDT1; chromatin licensing and DNA replication factor 1
D 111881188 CDT1-like protein a, chloroplastic K10727 CDT1; chromatin licensing and DNA replication factor 1
D 111881249 CDT1-like protein a, chloroplastic K10727 CDT1; chromatin licensing and DNA replication factor 1
D 111880061 cell division control protein 6 homolog B K02213 CDC6; cell division control protein 6
D 111912362 DNA replication licensing factor MCM2 K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D 111890880 DNA replication licensing factor MCM3 K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D 111912453 DNA replication licensing factor MCM4 K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
D 111908347 DNA replication licensing factor MCM5 K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
D 111893406 DNA replication licensing factor MCM6 K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D 111914339 DNA replication licensing factor MCM7 K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
D 111915562 uncharacterized protein LOC111915562 K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
C CDK (cyclin dependent kinase)
D 111889133 G2/mitotic-specific cyclin C13-1 K06627 CCNA; cyclin-A
D 111895651 cyclin-A1-4 isoform X1 K06627 CCNA; cyclin-A
D 111890706 G2/mitotic-specific cyclin C13-1 K06627 CCNA; cyclin-A
D 111918945 cyclin-A2-1 K06627 CCNA; cyclin-A
D 111913039 cyclin-A2-1 K06627 CCNA; cyclin-A
D 111917187 cyclin-A2-1 K06627 CCNA; cyclin-A
D 111877127 cyclin-A3-2 K06627 CCNA; cyclin-A
D 111920245 cell division control protein 2 homolog A K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
D 111878510 cell division control protein 2 homolog A K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
D 111878923 cell division control protein 2 homolog K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
C DDK (Dbf-4 dependent kinase)
D 111905122 uncharacterized protein LOC111905122 isoform X2 K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
C GINS complex
D 111910217 uncharacterized protein LOC111910217 K10732 GINS1; GINS complex subunit 1
D 111899476 DNA replication complex GINS protein PSF2 K10733 GINS2; GINS complex subunit 2
D 111911267 DNA replication complex GINS protein PSF3 K10734 GINS3; GINS complex subunit 3
D 111900625 DNA replication complex GINS protein SLD5 K10735 GINS4; GINS complex subunit 4
C Other initiation factors
D 111892018 BRCT domain-containing protein At4g02110 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D 111911871 uncharacterized protein LOC111911871 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D 111906266 ATP-dependent DNA helicase Q-like 5 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D 111907653 uncharacterized protein LOC111907653 K06628 CDC45; cell division control protein 45
D 111893105 probable DNA helicase MCM8 K10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]
D 111899088 probable DNA helicase MCM9 isoform X1 K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]
D 111899627 uncharacterized protein LOC111899627 K10736 MCM10; minichromosome maintenance protein 10
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
D 111876728 DNA polymerase alpha catalytic subunit K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
D 111881585 uncharacterized protein LOC111881585 K02321 POLA2; DNA polymerase alpha subunit B
D 111918788 uncharacterized protein LOC111918788 K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
D 111909695 probable DNA primase large subunit isoform X1 K02685 PRI2; DNA primase large subunit
C DNA polymerase epsilon complex
D 111905407 DNA polymerase epsilon catalytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
D 111896626 DNA polymerase epsilon catalytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
D 111893810 DNA polymerase epsilon subunit B K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
D 111917504 DNA polymerase II subunit B4 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
D 111881072 DNA polymerase II subunit B3-1 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
C DNA polymerase delta complex
D 111897619 DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
D 111908879 DNA polymerase delta small subunit K02328 POLD2; DNA polymerase delta subunit 2
D 111913871 uncharacterized protein LOC111913871 K03504 POLD3; DNA polymerase delta subunit 3
D 111921207 uncharacterized protein LOC111921207 K03505 POLD4; DNA polymerase delta subunit 4
C DNA polymerase gamma complex (mitochondrial)
C RPA (replication protein A)
D 111892538 replication protein A 70 kDa DNA-binding subunit A K07466 RFA1; replication factor A1
D 111905201 replication protein A 70 kDa DNA-binding subunit A K07466 RFA1; replication factor A1
D 111910499 replication protein A 70 kDa DNA-binding subunit B K07466 RFA1; replication factor A1
D 111892174 replication protein A 32 kDa subunit A K10739 RFA2; replication factor A2
D 111909598 replication protein A 32 kDa subunit B K10739 RFA2; replication factor A2
D 111920046 replication protein A 32 kDa subunit B K10739 RFA2; replication factor A2
D 111897084 replication protein A 14 kDa subunit B K10740 RPA3; replication factor A3
C RFC (replication factor C)
D 111914702 replication factor C subunit 1 isoform X1 K10754 RFC1; replication factor C subunit 1
D 111920799 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 111905574 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 111899774 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 111899159 uncharacterized protein LOC111899159 K10756 RFC3_5; replication factor C subunit 3/5
D 111906008 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 111884448 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
C RNase H
D 111916276 ribonuclease H2 subunit A K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
D 111897279 uncharacterized protein LOC111897279 isoform X1 K10744 RNASEH2B; ribonuclease H2 subunit B
D 111902901 uncharacterized protein C12B10.15c K10745 RNASEH2C; ribonuclease H2 subunit C
C Other elongation factors
D 111919730 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 111916510 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 111880340 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 111891830 DNA replication ATP-dependent helicase/nuclease JHS1 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D 111892034 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D 111915137 exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
D 111880618 exonuclease 1 isoform X1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
D 111883288 uncharacterized protein LOC111883288 K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D 111886023 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D 111920004 uncharacterized protein LOC111920004 K26118 ATAD5; ATPase family AAA domain-containing protein 5
B DNA Replication Termination Factors
C DNA methylation enzymes
D 111891835 DNA (cytosine-5)-methyltransferase CMT2 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 111905319 putative DNA (cytosine-5)-methyltransferase CMT1 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 111876994 DNA (cytosine-5)-methyltransferase CMT2 isoform X1 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 111878393 DNA (cytosine-5)-methyltransferase 1B isoform X1 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 111887753 DNA (cytosine-5)-methyltransferase CMT3 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 111884521 PWWP domain-containing protein 1 K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
C Prevention of re-replication factors
D 111889445 G2/mitotic-specific cyclin S13-7 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 111917727 cyclin-SDS K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 111915509 G2/mitotic-specific cyclin-2 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 111902543 G2/mitotic-specific cyclin-2 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 111901170 G2/mitotic-specific cyclin-2 isoform X1 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 111884954 putative cyclin-B3-1 isoform X1 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 111891045 G2/mitotic-specific cyclin-1-like K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 111883320 G2/mitotic-specific cyclin S13-7 isoform X1 K21777 CCNB; G2/mitotic-specific cyclin-B, other
C Telomere proteins
D Shelterin complex
E 111876523 uncharacterized protein LOC111876523 isoform X1 K11111 TERF2; telomeric repeat-binding factor 2
E 111881057 uncharacterized protein LOC111881057 K11111 TERF2; telomeric repeat-binding factor 2
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
E 111884534 CST complex subunit STN1 isoform X2 K23312 STN1; CST complex subunit STN1
E 111921672 CST complex subunit STN1 K23312 STN1; CST complex subunit STN1
E 111881958 CST complex subunit TEN1 isoform X2 K23313 TEN1; CST complex subunit TEN1
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D 111901173 telomerase reverse transcriptase K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Dyskerin complex
E 111917701 putative H/ACA ribonucleoprotein complex subunit 1-like protein 1 K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E 111904088 putative H/ACA ribonucleoprotein complex subunit 1-like protein 1 K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E 111915717 H/ACA ribonucleoprotein complex subunit 2-like protein K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E 111882552 H/ACA ribonucleoprotein complex subunit 2-like protein K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E 111891565 H/ACA ribonucleoprotein complex subunit 3-like protein K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
E 111881322 H/ACA ribonucleoprotein complex subunit 3-like protein K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
E 111920080 H/ACA ribonucleoprotein complex subunit 4 K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
E 111884937 H/ACA ribonucleoprotein complex subunit 4 K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
C Telomerase complex (fungi)
D 111901173 telomerase reverse transcriptase K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Sm core complex
E 111898104 uncharacterized protein LOC111898104 K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 111913215 uncharacterized protein LOC111913215 K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 111882531 uncharacterized protein LOC111882531 K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 111884756 small nuclear ribonucleoprotein SmD1a K11087 SNRPD1; small nuclear ribonucleoprotein D1
E 111886435 small nuclear ribonucleoprotein SmD1a K11087 SNRPD1; small nuclear ribonucleoprotein D1
E 111883104 uncharacterized protein LOC111883104 K11096 SNRPD2; small nuclear ribonucleoprotein D2
E 111908477 small nuclear ribonucleoprotein SmD3b K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 111878448 small nuclear ribonucleoprotein SmD3b K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 111910382 uncharacterized protein LOC111910382 K11097 SNRPE; small nuclear ribonucleoprotein E
E 111913910 uncharacterized protein LOC111913910 K11097 SNRPE; small nuclear ribonucleoprotein E
E 111899763 probable small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 111899764 probable small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 111882600 probable small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
C ELG1-RFC complex
D 111920799 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 111905574 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 111899774 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 111899159 uncharacterized protein LOC111899159 K10756 RFC3_5; replication factor C subunit 3/5
D 111906008 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 111884448 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
C MRN complex
D 111895473 double-strand break repair protein MRE11 isoform X2 K10865 MRE11; double-strand break repair protein MRE11
D 111895839 nibrin homolog K10867 NBN; nibrin
C Other termination factors
D 111913545 serine/threonine-protein kinase ATM isoform X1 K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 111880001 ATP-dependent DNA helicase Q-like SIM K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
D 111888247 ATP-dependent DNA helicase Q-like 4A isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D 111877989 ATP-dependent DNA helicase Q-like 4A K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D 111894227 ATP-dependent DNA helicase Q-like 3 isoform X2 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D 111907385 DNA repair endonuclease UVH1 isoform X1 K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D 111881230 poly [ADP-ribose] polymerase 1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
D 111892784 poly [ADP-ribose] polymerase 2 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 111905390 protein ADP-ribosyltransferase PARP3 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 111884229 G-patch domain-containing protein 1-like K11135 PINX1; Pin2-interacting protein X1
D 111886488 G-patch domain-containing protein 1 isoform X1 K11135 PINX1; Pin2-interacting protein X1
D 111878128 regulator of telomere elongation helicase 1 homolog K11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]
D 111880521 uncharacterized protein LOC111880521 K11137 TELO2; telomere length regulation protein
D 111881913 uncharacterized protein LOC111881913 K11138 RIF1; telomere-associated protein RIF1
D 111886186 uncharacterized protein LOC111886186 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 111898627 transcription factor Pur-alpha 1 K21772 PURA; transcriptional activator protein Pur-alpha
D 111902722 transcription factor Pur-alpha 1 K21772 PURA; transcriptional activator protein Pur-alpha
D 111906778 uncharacterized protein LOC111906778 K23314 WRAP53; telomerase Cajal body protein 1
D 111894558 uncharacterized protein LOC111894558 K25059 SDE2; replication stress response regulator SDE2
D 111905364 uncharacterized protein LOC111905364 K25186 RTF2; replication termination factor 2
B DNA Topoisomerases
C 111896260 DNA topoisomerase 1 alpha K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 111920094 DNA topoisomerase 1 alpha K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 111908304 DNA topoisomerase 2 isoform X1 K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C 111888272 DNA topoisomerase 3-beta isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
C 111909794 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D 111895877 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
D RNase H
D Other elongation factors
E 111920154 DNA polymerase I A, chloroplastic/mitochondrial K02335 polA; DNA polymerase I [EC:2.7.7.7]
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
D RFC (replication factor C)
D Other elongation factors
E 111891830 DNA replication ATP-dependent helicase/nuclease JHS1 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
E 111892034 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 111886023 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
C 111909688 DNA gyrase subunit A, chloroplastic/mitochondrial K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
C 111889396 DNA gyrase subunit B, chloroplastic/mitochondrial K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
C 111899829 DNA topoisomerase 6 subunit B K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
C 111879428 DNA topoisomerase 6 subunit B K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022