+F Repair protein KO
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DNA Repair and Recombination Proteins - Lacinutrix venerupis
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D BWR22_01290 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BWR22_07635 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E BWR22_08405 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E BWR22_02255 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E BWR22_08600 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D BWR22_12315 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BWR22_00605 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D BWR22_01290 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BWR22_07635 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D BWR22_07665 cryptochrome/photolyase family protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E BWR22_08405 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E BWR22_02255 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E BWR22_02195 DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E BWR22_08600 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E BWR22_00030 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E BWR22_00400 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E BWR22_10130 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E BWR22_14050 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E BWR22_08610 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E BWR22_06770 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E BWR22_11185 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E BWR22_01850 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E BWR22_06965 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BWR22_14050 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E BWR22_10130 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F BWR22_11410 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F BWR22_11405 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F BWR22_03990 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F BWR22_02280 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E BWR22_13135 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E BWR22_08425 DNA mismatch repair protein MutS K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E BWR22_10860 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
E BWR22_02820 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E BWR22_07380 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E BWR22_07010 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E BWR22_00900 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E BWR22_09340 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E BWR22_10015 exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E BWR22_10735 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D DNA ligase
E BWR22_10130 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E BWR22_06965 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BWR22_02260 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E BWR22_01465 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E BWR22_00435 recombinase RecA K03553 recA; recombination protein RecA
E BWR22_03080 Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E BWR22_03060 Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E BWR22_02935 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E BWR22_06315 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E BWR22_00435 recombinase RecA K03553 recA; recombination protein RecA
E BWR22_01775 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E BWR22_10885 DNA recombination protein RecF K03629 recF; DNA replication and repair protein RecF
E BWR22_06945 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E BWR22_00400 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E BWR22_01980 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E BWR22_11140 recombination protein RecR K06187 recR; recombination protein RecR
E BWR22_10070 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E BWR22_03080 Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E BWR22_03060 Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E BWR22_02935 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E BWR22_00355 hypothetical protein K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E BWR22_04100 ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F BWR22_06700 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F BWR22_04120 DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F BWR22_11075 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F BWR22_12390 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F BWR22_02250 integration host factor subunit beta K03530 hupB; DNA-binding protein HU-beta
F BWR22_09480 DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F BWR22_00400 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F BWR22_01980 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F BWR22_11140 recombination protein RecR K06187 recR; recombination protein RecR
F BWR22_10130 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F BWR22_09470 recombinase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F BWR22_10410 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F BWR22_08610 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F BWR22_06770 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F BWR22_11185 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D BWR22_01920 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D BWR22_02090 DNA polymerase V subunit UmuC K03502 umuC; DNA polymerase V
D BWR22_01715 peptidase S24 K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D BWR22_02095 hypothetical protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D BWR22_00435 recombinase RecA K03553 recA; recombination protein RecA
D BWR22_10070 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D BWR22_02260 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D BWR22_01465 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D BWR22_01965 recombinase RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D BWR22_07770 DNA ligase-associated DEXH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D BWR22_12315 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BWR22_00605 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D BWR22_02485 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D BWR22_02480 ribonucleotide reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D BWR22_10915 DHH family phosphoesterase K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024