+F Repair protein KO #

  DNA Repair and Recombination Proteins - Mycobacterium tuberculosis variant africanum

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D MAF_13380 ogt; putative methylated-DNA--protein-cysteine methyltransferase OGT K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] C BER (base exicision repair) D DNA glycosylases E MAF_29810 ung; putative uracil-DNA glycosylase UNG (UDG) K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E MAF_17050 mpg; putative 3-methyladenine DNA glycosylase MPG K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E MAF_36020 mutY; putative adenine glycosylase MUTY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E MAF_36810 nth; putative endonuclease III NTH (DNA-(apurinic or apyrimidinic site)lyase) K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex E DNA polymerase epsilon complex D Short Patch-BER factors D Other BER factors C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex E Cul4-CSA complex E Other TCR factor D TFIIH complex E MAF_08700 ercc3; putative DNA helicase ERCC3 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] D RPA (replication factor A) D Other NER factors C MMR (mismatch excision repair) D Mismatch and loop recognition factors D MutL homologs D DNA polymerase delta complex D RPA (replication factor A) D RFC (replication factor C) D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex D BRCA complex D RecA family proteins D Rad52 family proteins D Rad54 family proteins D RecQ family DNA helicases D Bloom's syndrome complex (BTR) D RPA (replication factor A) D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex D Other HR factors C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) D FANCD2-I complex D Downstream FA components D Other FA pathway factors C Other DSBR factors D Protein phosphatase 6 D Ubiquitin ligases D Others B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group C Other TLS factors B Check point factors C Rad9-Hus1-Rad1 complex C HRAD17(Rad24)-RFC complex C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex C Other check point factors B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex C Modulation of nucleotide pools D MAF_04150 mutT3; putative mutator protein MutT3 (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) (dGTP pyrophosphohydrolase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MAF_11780 mutT2; putative mutator protein MUTT (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MAF_27010 dut; putative deoxyuridine 5'-triphosphate nucleotidohydrolase DUT (DUTPase) (DUTP pyrophosphatase) K01520 dut; dUTP diphosphatase [EC:3.6.1.23] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D MAF_13380 ogt; putative methylated-DNA--protein-cysteine methyltransferase OGT K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] C BER (base exicision repair) D DNA glycosylases E MAF_29810 ung; putative uracil-DNA glycosylase UNG (UDG) K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E MAF_12780 conserved hypothetical protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] E MAF_13390 alkA; putative ADA regulatory protein ALKA (regulatory protein of adaptative response) K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21] E MAF_17050 mpg; putative 3-methyladenine DNA glycosylase MPG K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E MAF_36020 mutY; putative adenine glycosylase MUTY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E MAF_12290 tagA; putative DNA-3-methyladenine glycosylase I TAGA (TAG I) (3-methyladenine-DNA glycosylase I, constitutive) K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] E MAF_09530 putative formamidopyrimidine-DNA glycosylase (FAPY-DNA glycosylase) K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E MAF_29290 fpg; putative formamidopyrimidine-DNA glycosylase FPG (FAPY-DNA glycosylase) K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E MAF_24810 putative DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E MAF_33080 nei; putative endonuclease VIII NEI K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E MAF_36810 nth; putative endonuclease III NTH (DNA-(apurinic or apyrimidinic site)lyase) K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E MAF_04290 xthA; putative exodeoxyribonuclease III protein XTHA (exonuclease III) K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2] E MAF_06790 end; putative endonuclease IV end (endodeoxyribonuclease IV) (apurinase) K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D RecJ D DNA ligase E MAF_30200 ligA; putative DNA ligase [NAD dependent] LIGA (polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D DNA polymerase I E MAF_16410 polA; putative DNA polymerase I POLA K02335 polA; DNA polymerase I [EC:2.7.7.7] C NER (nucleotide excision repair) D GGR (global genome repair) factors E MAF_16500 uvrA; putative excinuclease ABC (subunit A-DNA-binding ATPase) UVRA K03701 uvrA; excinuclease ABC subunit A E MAF_16450 uvrB; putative excinuclease ABC (subunit B-helicase) UVRB K03702 uvrB; excinuclease ABC subunit B E MAF_14420 uvrC; putative excinuclease ABC (subunit C-nuclease) UVRC K03703 uvrC; excinuclease ABC subunit C E MAF_09580 uvrD1; putative ATP-dependent DNA helicase II UVRD1 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E MAF_32050 uvrD2; putative ATP-dependent DNA helicase II UVRD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E MAF_32090 putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E MAF_16410 polA; putative DNA polymerase I POLA K02335 polA; DNA polymerase I [EC:2.7.7.7] E MAF_30200 ligA; putative DNA ligase [NAD dependent] LIGA (polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) F MAF_06760 rpoB; DNA-directed RNA polymerase (beta chain) RPOB (transcriptase beta chain) K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] F MAF_06770 rpoC; DNA-directed RNA polymerase (beta' chain) RPOC (transcriptase beta' chain) K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] F MAF_34720 rpoA; putative DNA-directed RNA polymerase (alpha chain) RPOA (transcriptase alpha chain) K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] F MAF_14120 rpoZ; putative DNA-directed RNA polymerase (omega chain) RPOZ (transcriptase omega chain) K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] E TRCF (transcription-repair coupling factor) F MAF_10300 mfd; putative transcription-repair coupling factor MFD (TRCF) K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] C MMR (mismatch excision repair) D Mismatch and loop recognition factors D Molecular matchmaker D Strand discrimination factor D DNA exonucleases E MAF_11230 xseA; putative exodeoxyribonuclease VII (large subunit) XSEA K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E MAF_11220 xseB; putative exodeoxyribonuclease VII (small subunit) XSEA K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D DNA polymerase III holoenzyme E MAF_15740 dnaE1; putative DNA polymerase III (alpha chain) DNAE1 (DNA nucleotidyltransferase) K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E MAF_00020 dnaN; DNA polymerase III (beta chain) K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E MAF_24280 conserved hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E MAF_36510 putative DNA POLYMERASE K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E MAF_22020 conserved hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E MAF_37200 dnaQ; putative DNA polymerase III (epsilon subunit) DnaQ K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E MAF_37300 dnaZX; DNA polymerase III (subunit gamma/tau) DnaZ/X K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D DNA ligase E MAF_30200 ligA; putative DNA ligase [NAD dependent] LIGA (polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Other MMR factors E MAF_09580 uvrD1; putative ATP-dependent DNA helicase II UVRD1 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E MAF_32050 uvrD2; putative ATP-dependent DNA helicase II UVRD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E MAF_32090 putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E MAF_00540 ssb; putative single-strand binding protein Ssb (helix-destabilizing protein) K03111 ssb; single-strand DNA-binding protein E MAF_24950 conserved hypothetical protein K03111 ssb; single-strand DNA-binding protein B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins E MAF_06370 recB; putative exonuclease V (beta chain) RECB (exodeoxyribonuclease V beta chain) K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5] E MAF_06380 recC; putative exonuclease V (gamma chain) RECC (exodeoxyribonuclease V gamma chain) K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5] E MAF_06360 recD; putative exonuclease V (alpha chain) RECD (exodeoxyribonuclease V alpha chain) (exodeoxyribonuclease V polypeptide) K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] E MAF_27410 recA; RECA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RECA intein)] K03553 recA; recombination protein RecA E MAF_26100 ruvA; putative Holliday junction DNA helicase RUVA K03550 ruvA; holliday junction DNA helicase RuvA E MAF_26090 ruvB; putative Holliday junction DNA helicase RUVB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E MAF_26110 ruvC; putative crossover junction endodeoxyribonuclease RUVC (Holliday junction nuclease) K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] E MAF_14240 priA; putative primosomal protein N' PRIA (replication factor Y) K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D RecFOR pathway proteins E MAF_27410 recA; RECA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RECA intein)] K03553 recA; recombination protein RecA E MAF_35980 radA; DNA repair protein RADA (DNA repair protein SMS) K04485 radA; DNA repair protein RadA/Sms E MAF_00030 recF; DNA replication and repair protein K03629 recF; DNA replication and repair protein RecF E MAF_29790 recG; putative ATP-dependent DNA helicase RECG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E MAF_23760 conserved hypothetical protein K03584 recO; DNA repair protein RecO (recombination protein O) E MAF_37240 recR; putative recombination protein RecR K06187 recR; recombination protein RecR E MAF_17130 recN; putative DNA repair protein RECN (recombination protein N) K03631 recN; DNA repair protein RecN (Recombination protein N) E MAF_26100 ruvA; putative Holliday junction DNA helicase RUVA K03550 ruvA; holliday junction DNA helicase RuvA E MAF_26090 ruvB; putative Holliday junction DNA helicase RUVB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E MAF_26110 ruvC; putative crossover junction endodeoxyribonuclease RUVC (Holliday junction nuclease) K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D AddAB pathway proteins D Other HR factor E MAF_28220 conserved hypothetical protein K15342 cas1; CRISP-associated protein Cas1 D Archaeal homologous recombinant proteins E MAF_25250 conserved hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex E MAF_09460 conserved hypothetical protein K10979 ku; DNA end-binding protein Ku E MAF_09470 putative ATP dependent DNA ligase (ATP dependent polydeoxyribonucleotide synthase) K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F MAF_00060 gyrA; DNA gyrase (subunit A) K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F MAF_00050 gyrB; DNA gyrase (subunit B) K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F MAF_36530 topA; DNA topoisomerase I TOPA (omega-protein) (relaxing enzyme) K03168 topA; DNA topoisomerase I [EC:5.6.2.1] E Supressor F MAF_29910 hupB; putative DNA-binding protein HU homolog HUPB (histone-like protein) K03530 hupB; DNA-binding protein HU-beta D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway F MAF_23760 conserved hypothetical protein K03584 recO; DNA repair protein RecO (recombination protein O) F MAF_37240 recR; putative recombination protein RecR K06187 recR; recombination protein RecR F MAF_30200 ligA; putative DNA ligase [NAD dependent] LIGA (polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E Facilitator E Supressor F MAF_16500 uvrA; putative excinuclease ABC (subunit A-DNA-binding ATPase) UVRA K03701 uvrA; excinuclease ABC subunit A F MAF_16450 uvrB; putative excinuclease ABC (subunit B-helicase) UVRB K03702 uvrB; excinuclease ABC subunit B B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D MAF_15640 dinX; putative DNA polymerase IV DINX (POL IV 1) (DNA nucleotidyltransferase (DNA-directed)) K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D MAF_30630 dinP; putative DNA-damage-inducible protein P DINP (DNA polymerase V) K02346 dinB; DNA polymerase IV [EC:2.7.7.7] C Other SOS response factors D MAF_27410 recA; RECA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RECA intein)] K03553 recA; recombination protein RecA D MAF_27240 lexA; REPRESSOR LEXA K01356 lexA; repressor LexA [EC:3.4.21.88] D MAF_17130 recN; putative DNA repair protein RECN (recombination protein N) K03631 recN; DNA repair protein RecN (Recombination protein N) D MAF_34070 conserved hypothetical protein K14161 imuB; protein ImuB D MAF_33850 dnaE2; putative DNA polymerase III (alpha chain) DNAE2 (DNA nucleotidyltransferase) K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7] D MAF_00540 ssb; putative single-strand binding protein Ssb (helix-destabilizing protein) K03111 ssb; single-strand DNA-binding protein D MAF_24950 conserved hypothetical protein K03111 ssb; single-strand DNA-binding protein D MAF_27400 recX; REGULATORY protein RECX K03565 recX; regulatory protein B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases D MAF_13530 dinG; putative ATP-dependent helicase DING K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D MAF_33070 lhr; putative ATP-dependent helicase LHR (large helicase-related protein) K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] C Modulation of nucleotide pools D MAF_04150 mutT3; putative mutator protein MutT3 (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) (dGTP pyrophosphohydrolase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MAF_11780 mutT2; putative mutator protein MUTT (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MAF_29900 mutT1; putative hydrolase MUTT1 K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69] D MAF_17180 conserved hypothetical protein K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58] D MAF_27010 dut; putative deoxyuridine 5'-triphosphate nucleotidohydrolase DUT (DUTPase) (DUTP pyrophosphatase) K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D MAF_05770 nrdZ; putative ribonucleoside-diphosphate reductase (large subunit) NRDZ (ribonucleotide reductase) K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D MAF_30580 nrdE; ribonucleoside-diphosphate reductase (alpha chain) NRDE (ribonucleotide reductase small subunit) K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D MAF_02330 nrdB; putative ribonucleoside-diphosphate reductase (beta chain) NrdB (ribonucleotide reductase small chain) K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D MAF_19920 nrdF1; ribonucleoside-diphosphate reductase (beta chain) NRDF1 (ribonucleotide reductase small subunit) K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D MAF_30550 nrdF2; ribonucleoside-diphosphate reductase (beta chain) NRDF2 (ribonucleotide reductase small subunit) K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C Others D MAF_28420 conserved hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 29, 2025