+F Repair protein KO
#
DNA Repair and Recombination Proteins - Metarhizium robertsii
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MAA_02658 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MAA_05216 photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E MAA_00665 Uracil-DNA glycosylase, active site protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MAA_00707 DNA glycosylase, G/T mismatch K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E MAA_00480 A/G-specific adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MAA_04344 N-glycosylase/DNA lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E MAA_02902 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E MAA_04759 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E MAA_00232 apurinic/apyrimidinic endonuclease-like protein K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E MAA_03720 DNA lyase K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F MAA_09459 DNA polymerase family B K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F MAA_00130 DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2
F MAA_02724 DNA polymerase subunit Cdc27 K03504 POLD3; DNA polymerase delta subunit 3
F MAA_02554 DNA polymerase delta subunit K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F MAA_04664 DNA polymerase epsilon, catalytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F MAA_04417 DNA polymerase alpha/epsilon, subunit B K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F MAA_03890 DNA polymerase epsilon subunit D K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F MAA_01155 Histone-fold protein K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E MAA_03917 Proliferating cell nuclear antigen, PCNA K04802 PCNA; proliferating cell nuclear antigen
E MAA_04932 Rad27p/FEN-1 endonuclease-like protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E MAA_03560 DNA ligase (Polydeoxyribonucleotide synthase) K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
E MAA_06538 tyrosyl-DNA phosphodiesterase K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E MAA_07304 DEAD/DEAH box helicase K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E MAA_05467 polynucleotide kinase 3 phosphatase K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E MAA_11764 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E MAA_06190 polymerase 2 ADP-ribosyltransferase 2 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E MAA_00202 poly(ADP)-ribose polymerase K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F MAA_06081 DNA repair rad4-like protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F MAA_10703 homocitrate synthase K10838 XPC; xeroderma pigmentosum group C-complementing protein
F MAA_05868 UV excision repair protein Rad23 K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F MAA_00593 zinc finger domain-containing protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F MAA_03473 Cullin K10609 CUL4; cullin 4
F MAA_06283 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
F MAA_06157 DNA repair protein Rad7 K15082 RAD7; DNA repair protein RAD7
F MAA_06158 DNA repair protein RAD16 K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F MAA_00658 DNA-directed RNA polymerase II largest subunit K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F MAA_00336 DNA-dependent RNA polymerase II beta subunit K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F MAA_01802 hypothetical protein K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F MAA_03940 polymerase (RNA) II (DNA directed) polypeptide D K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F MAA_06406 RNA polymerase, subunit H/Rpb5 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F MAA_07079 DNA-directed RNA polymerase, subunit K/RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F MAA_07225 RNA polymerase Rpb7-like domain-containing protein K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F MAA_02710 UDP-glucose 4-epimerase Gal10 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F MAA_07111 DNA-directed RNA polymerase, M/15kDa subunit K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F MAA_00683 RNA polymerase, subunit N/RPB10 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F MAA_07862 DNA-directed RNA polymerase II subunit RPB11 K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F MAA_09479 hypothetical protein K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F MAA_00593 zinc finger domain-containing protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F MAA_03473 Cullin K10609 CUL4; cullin 4
F MAA_06283 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
F MAA_02912 DNA excision repair protein ERCC-8 K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F MAA_01908 transcription-coupled repair protein CSB/RAD26 K10841 ERCC6; DNA excision repair protein ERCC-6
F MAA_03649 hypothetical protein K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E MAA_05948 Rad3 protein K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E MAA_05298 DNA excision repair helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E MAA_05311 RNA polymerase II transcription factor K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E MAA_04765 TFIIH basal transcription factor complex, subunit SSL1 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E MAA_02632 transcription factor TFIIH subunit Tfb4 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E MAA_02366 transcription factor tfb2-like protein K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E MAA_03038 DNA repair protein Rex1 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E MAA_06809 serine/threonine-protein kinase K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E MAA_04978 Cyclin-related protein K06634 CCNH; cyclin H
E MAA_08083 hypothetical protein K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E MAA_02994 replication factor-A protein 1 K07466 RFA1; replication factor A1
E MAA_06454 DNA-directed RNA polymerase I subunit RPA1 K10739 RFA2; replication factor A2
E MAA_01332 replication factor A protein 3 K10740 RPA3; replication factor A3
D Other NER factors
E MAA_08572 hypothetical protein K10847 XPA; DNA-repair protein complementing XP-A cells
E MAA_02005 DNA repair protein rad10 K10849 ERCC1; DNA excision repair protein ERCC-1
E MAA_03851 DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E MAA_00674 DNA excision repair protein Rad2 K10846 ERCC5; DNA excision repair protein ERCC-5
E MAA_03560 DNA ligase (Polydeoxyribonucleotide synthase) K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E MAA_03391 hypothetical protein K15075 MET18; DNA repair/transcription protein MET18/MMS19
E MAA_04354 cullin-3 K03869 CUL3; cullin 3
E MAA_07608 Skp1 family protein K03872 ELOC; elongin-C
E MAA_03948 RNA polymerase II transcription factor SIII (Elongin) subunit A K15077 ELA1; elongin-A
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E MAA_04555 DNA mismatch repair protein MSH2 K08735 MSH2; DNA mismatch repair protein MSH2
E MAA_05665 DNA mismatch repair protein K08736 MSH3; DNA mismatch repair protein MSH3
E MAA_06876 DNA repair protein K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E MAA_06457 DNA mismatch repair protein Mlh1 K08734 MLH1; DNA mismatch repair protein MLH1
E MAA_10738 Peptidase S8/S53, subtilisin/kexin/sedolisin K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E MAA_09459 DNA polymerase family B K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E MAA_00130 DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2
E MAA_02724 DNA polymerase subunit Cdc27 K03504 POLD3; DNA polymerase delta subunit 3
E MAA_02554 DNA polymerase delta subunit K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E MAA_02994 replication factor-A protein 1 K07466 RFA1; replication factor A1
E MAA_06454 DNA-directed RNA polymerase I subunit RPA1 K10739 RFA2; replication factor A2
E MAA_01332 replication factor A protein 3 K10740 RPA3; replication factor A3
D RFC (replication factor C)
E MAA_07632 replication factor C, subunit 1-like protein K10754 RFC1; replication factor C subunit 1
E MAA_07213 activator 1 41 kDa subunit K10755 RFC2_4; replication factor C subunit 2/4
E MAA_09420 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
E MAA_07634 replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
E MAA_11081 Ubiquitin-conjugating enzyme/RWD-like protein K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E MAA_03917 Proliferating cell nuclear antigen, PCNA K04802 PCNA; proliferating cell nuclear antigen
E MAA_04616 nuclease-like protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E MAA_03560 DNA ligase (Polydeoxyribonucleotide synthase) K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E MAA_06725 WD repeat containing protein K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E MAA_08335 DNA repair protein rad32 K10865 MRE11; double-strand break repair protein MRE11
E MAA_07439 Recombination/repair protein Rad50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
E MAA_08335 DNA repair protein rad32 K10865 MRE11; double-strand break repair protein MRE11
E MAA_07439 Recombination/repair protein Rad50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA complex
E MAA_04013 Nucleoporin Nup120/160 K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E MAA_04013 Nucleoporin Nup120/160 K04482 RAD51; DNA repair protein RAD51
E MAA_01880 DNA repair protein rhp57 K10958 RAD57; DNA repair protein RAD57
D Rad52 family proteins
E MAA_02837 DNA repair protein K10873 RAD52; DNA repair and recombination protein RAD52
D Rad54 family proteins
E MAA_04463 SWI/SNF family of DNA-dependent ATPase K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
E MAA_06036 DNA topoisomerase K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E MAA_04579 RecQ mediated genome instability protein Rmi1 K15364 NCE4; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E MAA_02994 replication factor-A protein 1 K07466 RFA1; replication factor A1
E MAA_06454 DNA-directed RNA polymerase I subunit RPA1 K10739 RFA2; replication factor A2
E MAA_01332 replication factor A protein 3 K10740 RPA3; replication factor A3
D Protein phosphatase 4
E MAA_06332 suppressor of Mek1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E MAA_07374 structural maintenance of chromosome complex subunit SmcA K22803 SMC5; structural maintenance of chromosomes protein 5
E MAA_04495 RecF/RecN/SMC protein K22804 SMC6; structural maintenance of chromosomes protein 6
E MAA_01231 Nse1 non-SMC component of SMC5-6 complex K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E MAA_02251 chromosomal organization and DNA repair protein Mms21 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E MAA_10941 hypothetical protein K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E MAA_08301 ERCC4 domain-containing protein K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E MAA_03931 endonuclease K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E MAA_08658 dss1/sem1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E MAA_01435 GIY-YIG catalytic domain containing protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E MAA_05373 flap structure-specific endonuclease K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E MAA_02562 histone acetylase complex subunit K11339 MORF4L1; mortality factor 4-like protein 1
E MAA_04482 ATPase, AAA-type, core K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E MAA_00617 WLM domain-containing protein K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
E MAA_04169 helicase C-terminal domain protein K14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E MAA_01143 ku70 protein K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E MAA_06032 von Willebrand factor, type A K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
D MRX complex
E MAA_08335 DNA repair protein rad32 K10865 MRE11; double-strand break repair protein MRE11
E MAA_07439 Recombination/repair protein Rad50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E MAA_09935 DNA ligase K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E MAA_09188 ATP dependent DNA ligase domain protein K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
E MAA_03665 Nucleotidyltransferase K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
E MAA_04101 DNA polymerase K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
D Other NHEJ factors
E MAA_07304 DEAD/DEAH box helicase K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E MAA_01921 artemis protein K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E MAA_01513 endonuclease/exonuclease/phosphatase family protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E MAA_03877 endonuclease/exonuclease/phosphatase family protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
E MAA_00133 Histone-fold protein K11511 APITD1; centromere protein S
D Bloom's syndrome complex (BTR)
E MAA_06036 DNA topoisomerase K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E MAA_04579 RecQ mediated genome instability protein Rmi1 K15364 NCE4; RecQ-mediated genome instability protein 1
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
E MAA_04347 coiled-coil domain-containing protein MTMR15 K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E MAA_04013 Nucleoporin Nup120/160 K04482 RAD51; DNA repair protein RAD51
E MAA_04333 Telomere length regulation protein K11137 TELO2; telomere length regulation protein
E MAA_05349 WD repeat protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
E MAA_06287 WD40 repeat-like-containing domain protein K23314 WRAP53; telomerase Cajal body protein 1
E MAA_05925 WD repeat domain-containing protein K24752 WDR70; WD repeat-containing protein 70
E MAA_06725 WD repeat containing protein K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D MAA_03701 sister chromatid cohesion protein Eso1 K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D MAA_10612 DUF726 domain protein K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D MAA_00563 DNA-directed polymerase kappa K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D MAA_04029 DNA-repair protein, UmuC-lik K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D MAA_03713 DNA polymerase family B K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D MAA_06481 Ubiquitin-conjugating enzyme, active site protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D MAA_02723 DNA repair protein, Rad18 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D MAA_10679 Cystathionine beta-synthase, core K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
D MAA_05066 SNF2 family domain-containing protein K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D MAA_06224 DNA repair and recombination protein RAD5C K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D MAA_02056 Ubiquitin-conjugating enzyme, E2 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D MAA_00823 Ubiquitin-conjugating enzyme, active site protein K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D MAA_03917 Proliferating cell nuclear antigen, PCNA K04802 PCNA; proliferating cell nuclear antigen
D MAA_04455 HMG box-containing protein K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D MAA_02502 DNA repair protein Rad9 K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D MAA_01477 NUV101 protein K10903 HUS1; HUS1 checkpoint protein
D MAA_05173 Repair protein Rad1/Rec1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D MAA_04096 cell cycle checkpoint protein RAD17 K06662 HRAD17; cell cycle checkpoint protein
D MAA_07213 activator 1 41 kDa subunit K10755 RFC2_4; replication factor C subunit 2/4
D MAA_09420 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D MAA_07634 replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
D MAA_11081 Ubiquitin-conjugating enzyme/RWD-like protein K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D MAA_05173 Repair protein Rad1/Rec1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D MAA_07858 drug resistance protein MdrA K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D MAA_08776 Replication fork protection component Swi3 K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D MAA_02819 DNA replication checkpoint mediator K11272 MRC1; mediator of replication checkpoint protein 1
C Triple T complex
D MAA_04333 Telomere length regulation protein K11137 TELO2; telomere length regulation protein
D MAA_03427 HEAT repeat protein K20403 TTI1; TELO2-interacting protein 1
C BAG6-UBL4A-GET4 complex
D MAA_07687 Ubiquitin supergroup K23388 UBL4; ubiquitin-like protein 4
D MAA_07592 protein family UPF0363 K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D MAA_11390 hypothetical protein K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D MAA_03471 phosphatidylinositol 3-kinase-like protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D MAA_00521 serine/threonine protein kinase K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D MAA_05678 SMAD/FHA protein kinase K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D MAA_04151 rhodanese-like domain-containing protein K02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
D MAA_05714 14-3-3 protein K06630 YWHAE; 14-3-3 protein epsilon
D MAA_07273 14-3-3 protein K06630 YWHAE; 14-3-3 protein epsilon
D MAA_03072 Protein kinase-like protein K03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
D MAA_03626 Transcription factor, fork head K24664 FKH; forkhead protein FKH
D MAA_04951 vacuolar protein sorting-associated protein VPS4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D MAA_06109 vacuolar protein sorting-associated protein VPS4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D MAA_07658 hypothetical protein K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D MAA_04152 DNA polymerase V K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D MAA_04336 DNA cross-link repair protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D MAA_10671 prefoldin subunit K05986 NUCS; nuclease S1 [EC:3.1.30.1]
D MAA_10268 S1/P1 Nuclease K05986 NUCS; nuclease S1 [EC:3.1.30.1]
D MAA_07393 nuclease S1 K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
D MAA_03082 SNF2 superfamily RAD26-like protein K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D MAA_02421 cell cycle control protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D MAA_05055 pre-mRNA splicing factor CEF1 K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D MAA_04425 BCAS2 family protein K12861 BCAS2; pre-mRNA-splicing factor SPF27
D MAA_00220 pre-mRNA splicing factor prp46 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D MAA_09111 NUDIX hydrolase domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MAA_09113 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MAA_00285 NUDIX hydrolase domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MAA_04003 dUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MAA_08816 large subunit of ribonucleoside-diphosphate reductase K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D MAA_03602 ribonucleoside-diphosphate reductase M2 subunit K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MAA_02658 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MAA_05216 photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E MAA_00665 Uracil-DNA glycosylase, active site protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MAA_03026 HhH-GPD superfamily base excision DNA repair protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E MAA_00480 A/G-specific adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MAA_02249 DNA glycosylase/AP lyase, catalytic domain protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MAA_02902 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E MAA_04759 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E MAA_02217 ATP-dependent DNA helicase srs2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E MAA_02217 ATP-dependent DNA helicase srs2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D MAA_09111 NUDIX hydrolase domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MAA_09113 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MAA_00285 NUDIX hydrolase domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MAA_04003 dUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024