+D GENES KO
#
KEGG Orthology (KO) - Metamycoplasma alkalescens
%
!
A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:mala00010]
D NCTC10135_00036 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D NCTC10135_00369 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D NCTC10135_01097 gap_1; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D NCTC10135_00672 pgk_1; Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D NCTC10135_00073 pgm; phosphoglyceromutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D NCTC10135_00425 eno_2; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NCTC10135_00426 eno_3; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NCTC10135_01115 pyk_1; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D NCTC10135_01116 pyk_2; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D NCTC10135_01327 pdhA_2; Pyruvate dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D NCTC10135_01324 pdhB_2; pyruvate dehydrogenase E1 component, beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D NCTC10135_01320 pdhC_1; pyruvate dehydrogenase E2 component K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D NCTC10135_01321 pdhC_2; branched-chain alpha-keto acid dehydrogenase subunit E2 K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D NCTC10135_01319 pdhD; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D NCTC10135_00088 ldh_1; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D NCTC10135_01341 adhT; Alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D NCTC10135_00767 fdhA; Glutathione-independent formaldehyde dehydrogenase K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D NCTC10135_00768 Uncharacterised protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
C 00020 Citrate cycle (TCA cycle) [PATH:mala00020]
D NCTC10135_01319 pdhD; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D NCTC10135_01327 pdhA_2; Pyruvate dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D NCTC10135_01324 pdhB_2; pyruvate dehydrogenase E1 component, beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D NCTC10135_01320 pdhC_1; pyruvate dehydrogenase E2 component K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D NCTC10135_01321 pdhC_2; branched-chain alpha-keto acid dehydrogenase subunit E2 K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00030 Pentose phosphate pathway [PATH:mala00030]
D NCTC10135_00967 rpe; d-ribulose-5-phosphate 3 epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D NCTC10135_00541 tkt_2; Transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D NCTC10135_01303 rpiB; ribose-5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D NCTC10135_00282 xpkA_5; Xylulose-5-phosphate phosphoketolase K01621 xfp; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22]
D NCTC10135_01205 deoC; Deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]
D NCTC10135_01105 deoB_1; Phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7]
D NCTC10135_01108 deoB_2; Phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7]
D NCTC10135_00095 prs; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D NCTC10135_00036 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
C 00040 Pentose and glucuronate interconversions
D NCTC10135_00967 rpe; d-ribulose-5-phosphate 3 epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
C 00051 Fructose and mannose metabolism [PATH:mala00051]
D NCTC10135_00036 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D NCTC10135_00369 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D NCTC10135_01303 rpiB; ribose-5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
C 00052 Galactose metabolism
C 00053 Ascorbate and aldarate metabolism
C 00500 Starch and sucrose metabolism
C 00520 Amino sugar and nucleotide sugar metabolism
C 00620 Pyruvate metabolism [PATH:mala00620]
D NCTC10135_01327 pdhA_2; Pyruvate dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D NCTC10135_01324 pdhB_2; pyruvate dehydrogenase E1 component, beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D NCTC10135_01320 pdhC_1; pyruvate dehydrogenase E2 component K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D NCTC10135_01321 pdhC_2; branched-chain alpha-keto acid dehydrogenase subunit E2 K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D NCTC10135_01319 pdhD; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D NCTC10135_01341 adhT; Alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D NCTC10135_00767 fdhA; Glutathione-independent formaldehyde dehydrogenase K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D NCTC10135_00768 Uncharacterised protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D NCTC10135_00122 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D NCTC10135_01318 pta; phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D NCTC10135_01115 pyk_1; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D NCTC10135_01116 pyk_2; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D NCTC10135_00088 ldh_1; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D NCTC10135_00019 rnjA; hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:mala00630]
D NCTC10135_01018 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D NCTC10135_01319 pdhD; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00640 Propanoate metabolism [PATH:mala00640]
D NCTC10135_00122 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D NCTC10135_01318 pta; phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D NCTC10135_01326 pdhA_1; Pyruvate dehydrogenase E1 component subunit alpha K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D NCTC10135_01319 pdhD; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D NCTC10135_00088 ldh_1; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
C 00650 Butanoate metabolism
C 00660 C5-Branched dibasic acid metabolism
C 00562 Inositol phosphate metabolism
D NCTC10135_00369 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:mala00190]
D NCTC10135_00274 atpA_1; ATP synthase F0F1 subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D NCTC10135_00276 atpD-2; ATP synthase F1 subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D NCTC10135_00744 atpD; ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D NCTC10135_00745 MCYN0314; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D NCTC10135_00748 atpH; F0F1 ATP synthase subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D NCTC10135_00743 atpC; ATP synthase subunit epsilon K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D NCTC10135_00751 F0F1 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D NCTC10135_00749 atpF; ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D NCTC10135_00750 atpE; ATP synthase subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D NCTC10135_00746 atpA_2; ATP synthase F0F1 subunit alpha K02132 ATPeF1A; F-type H+-transporting ATPase subunit alpha
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:mala00710]
D NCTC10135_00672 pgk_1; Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D NCTC10135_01097 gap_1; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D NCTC10135_00036 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D NCTC10135_00541 tkt_2; Transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D NCTC10135_01303 rpiB; ribose-5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D NCTC10135_00369 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D NCTC10135_00967 rpe; d-ribulose-5-phosphate 3 epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
C 00720 Other carbon fixation pathways [PATH:mala00720]
D NCTC10135_00569 folD; methylenetetrahydrofolate dehydrogenase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D NCTC10135_00069 Bacterial protein of uncharacterised function (DUF885) K01500 fchA; methenyltetrahydrofolate cyclohydrolase [EC:3.5.4.9]
D NCTC10135_01318 pta; phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D NCTC10135_00122 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
C 00680 Methane metabolism [PATH:mala00680]
D NCTC10135_01018 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D NCTC10135_00425 eno_2; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NCTC10135_00426 eno_3; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NCTC10135_00036 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D NCTC10135_00122 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D NCTC10135_01318 pta; phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D NCTC10135_00073 pgm; phosphoglyceromutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
C 00910 Nitrogen metabolism
D NCTC10135_00025 arcC; Carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
C 00920 Sulfur metabolism
D NCTC10135_00920 Predicted phosphohydrolase (DHH superfamily) K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
D NCTC10135_01309 nrnA; Bifunctional oligoribonuclease and PAP phosphatase nrnA K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis
D NCTC10135_00531 acpP; acyl carrier protein, putative K02078 acpP; acyl carrier protein
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation
D NCTC10135_01341 adhT; Alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D NCTC10135_00767 fdhA; Glutathione-independent formaldehyde dehydrogenase K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D NCTC10135_00768 Uncharacterised protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:mala00561]
D NCTC10135_01021 plsX_1; fatty acid/phospholipid synthesis protein PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D NCTC10135_01022 plsX_2; putative glycerol-3-phosphate acyltransferase PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D NCTC10135_01090 plsY; G3P acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D NCTC10135_01246 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 00564 Glycerophospholipid metabolism [PATH:mala00564]
D NCTC10135_00512 gpsA_1; glycerol-3-phosphate dehydrogenase K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D NCTC10135_00513 gpsA_2; glycerol-3-phosphate dehydrogenase K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D NCTC10135_01090 plsY; G3P acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D NCTC10135_01246 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D NCTC10135_00590 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K08744 CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:mala00230]
D NCTC10135_01105 deoB_1; Phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7]
D NCTC10135_01108 deoB_2; Phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7]
D NCTC10135_00095 prs; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D NCTC10135_01156 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D NCTC10135_01209 deoD; purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]
D NCTC10135_00574 hpt; hypoxanthine-guanine phosphoribosyltransferases K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
D NCTC10135_00815 RNA pyrophosphohydrolase K01518 NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]
D NCTC10135_00970 gmk; guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D NCTC10135_00341 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D NCTC10135_00025 arcC; Carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
C 00240 Pyrimidine metabolism [PATH:mala00240]
D NCTC10135_01039 pyrH_1; UMP kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D NCTC10135_00815 RNA pyrophosphohydrolase K01518 NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]
D NCTC10135_01204 upp; uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D NCTC10135_01206 deoA; Thymidine phosphorylase K00756 pdp; pyrimidine-nucleoside phosphorylase [EC:2.4.2.2]
D NCTC10135_01208 pdp_2; Pyrimidine-nucleoside phosphorylase K00756 pdp; pyrimidine-nucleoside phosphorylase [EC:2.4.2.2]
D NCTC10135_00392 cdd; Cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5]
D NCTC10135_01207 pdp_1; Pyrimidine-nucleoside phosphorylase K00758 deoA; thymidine phosphorylase [EC:2.4.2.4]
D NCTC10135_00729 tdk; thymidine kinase K00857 tdk; thymidine kinase [EC:2.7.1.21]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:mala00250]
D NCTC10135_00099 Uncharacterised protein K13566 NIT2; omega-amidase [EC:3.5.1.3]
C 00260 Glycine, serine and threonine metabolism [PATH:mala00260]
D NCTC10135_01018 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D NCTC10135_00073 pgm; phosphoglyceromutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D NCTC10135_01319 pdhD; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00270 Cysteine and methionine metabolism [PATH:mala00270]
D NCTC10135_00675 metK_2; S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D NCTC10135_00007 pfs; 5-methylthioadenosine nucleosidase/S-adenosylhomoc ystein nucleosidase K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9]
D NCTC10135_00088 ldh_1; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
C 00280 Valine, leucine and isoleucine degradation [PATH:mala00280]
D NCTC10135_01326 pdhA_1; Pyruvate dehydrogenase E1 component subunit alpha K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D NCTC10135_01319 pdhD; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00290 Valine, leucine and isoleucine biosynthesis
C 00300 Lysine biosynthesis
D NCTC10135_00604 glyQS_1; Glycine--tRNA ligase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00310 Lysine degradation
D NCTC10135_01319 pdhD; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00220 Arginine biosynthesis [PATH:mala00220]
D NCTC10135_00022 argF; Ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D NCTC10135_00038 arcA_1; arginine deiminase domain-containing protein K01478 arcA; arginine deiminase [EC:3.5.3.6]
D NCTC10135_00025 arcC; Carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
C 00330 Arginine and proline metabolism
C 00340 Histidine metabolism
C 00350 Tyrosine metabolism
D NCTC10135_01341 adhT; Alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D NCTC10135_00767 fdhA; Glutathione-independent formaldehyde dehydrogenase K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D NCTC10135_00768 Uncharacterised protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
C 00360 Phenylalanine metabolism
C 00380 Tryptophan metabolism
D NCTC10135_01319 pdhD; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:mala00400]
D NCTC10135_00071 Uncharacterised protein K04518 pheA2; prephenate dehydratase [EC:4.2.1.51]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism
C 00430 Taurine and hypotaurine metabolism [PATH:mala00430]
D NCTC10135_01318 pta; phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D NCTC10135_00122 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:mala00450]
D NCTC10135_01181 csd; Probable cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D NCTC10135_01182 sufS; Cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D NCTC10135_00453 trxB; thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
C 00460 Cyanoamino acid metabolism
D NCTC10135_01018 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism
D NCTC10135_00398 alanine racemase K21898 orr; ornithine racemase [EC:5.1.1.12]
C 00480 Glutathione metabolism [PATH:mala00480]
D NCTC10135_00978 pepA_2; Cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D NCTC10135_00241 Uncharacterised protein K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis
C 00550 Peptidoglycan biosynthesis
D NCTC10135_00064 Bacterial protein of uncharacterised function (DUF885) K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 00552 Teichoic acid biosynthesis
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:mala00730]
D NCTC10135_00894 thiI; thiamine biosynthesis protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D NCTC10135_00968 engC; GTPase YjeQ/EngC K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
D NCTC10135_00341 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:mala00740]
D NCTC10135_01203 COF family HAD hydrolase protein K21064 ycsE; 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.104]
D NCTC10135_00370 ribF; riboflavin kinase K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]
C 00750 Vitamin B6 metabolism
C 00760 Nicotinate and nicotinamide metabolism [PATH:mala00760]
D NCTC10135_01312 pncB; nicotinic acid phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D NCTC10135_01209 deoD; purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]
D NCTC10135_01178 coaD; pantetheine-phosphate adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]
C 00770 Pantothenate and CoA biosynthesis
C 00780 Biotin metabolism
C 00785 Lipoic acid metabolism [PATH:mala00785]
D NCTC10135_01328 lplA; Lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D NCTC10135_01319 pdhD; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D NCTC10135_01327 pdhA_2; Pyruvate dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D NCTC10135_01324 pdhB_2; pyruvate dehydrogenase E1 component, beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D NCTC10135_01320 pdhC_1; pyruvate dehydrogenase E2 component K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D NCTC10135_01321 pdhC_2; branched-chain alpha-keto acid dehydrogenase subunit E2 K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D NCTC10135_01326 pdhA_1; Pyruvate dehydrogenase E1 component subunit alpha K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
C 00790 Folate biosynthesis
C 00670 One carbon pool by folate [PATH:mala00670]
D NCTC10135_00569 folD; methylenetetrahydrofolate dehydrogenase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D NCTC10135_00069 Bacterial protein of uncharacterised function (DUF885) K01500 fchA; methenyltetrahydrofolate cyclohydrolase [EC:3.5.4.9]
D NCTC10135_01018 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D NCTC10135_00975 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis
D NCTC10135_00064 Bacterial protein of uncharacterised function (DUF885) K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D NCTC10135_00541 tkt_2; Transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis
D NCTC10135_00604 glyQS_1; Glycine--tRNA ligase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis
C 00401 Novobiocin biosynthesis
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
C 00333 Prodigiosin biosynthesis
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
D NCTC10135_00531 acpP; acyl carrier protein, putative K02078 acpP; acyl carrier protein
C 00999 Biosynthesis of various plant secondary metabolites
D NCTC10135_00675 metK_2; S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
C 00997 Biosynthesis of various other secondary metabolites
D NCTC10135_00398 alanine racemase K21898 orr; ornithine racemase [EC:5.1.1.12]
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation
C 00627 Aminobenzoate degradation
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation [PATH:mala00625]
D NCTC10135_01341 adhT; Alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D NCTC10135_00767 fdhA; Glutathione-independent formaldehyde dehydrogenase K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D NCTC10135_00768 Uncharacterised protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation [PATH:mala00626]
D NCTC10135_01341 adhT; Alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D NCTC10135_00767 fdhA; Glutathione-independent formaldehyde dehydrogenase K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D NCTC10135_00768 Uncharacterised protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:mala03020]
D NCTC10135_00262 rpoB_4; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D NCTC10135_00346 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D NCTC10135_00600 Uncharacterised protein K03048 rpoE; DNA-directed RNA polymerase subunit delta
D NCTC10135_00261 rpoB_3; DNA-directed RNA polymerase subunit beta K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D NCTC10135_00269 rpoC_4; DNA-directed RNA polymerase subunit beta' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
C 03022 Basal transcription factors
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:mala03010]
D NCTC10135_00042 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D NCTC10135_00322 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D NCTC10135_00447 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D NCTC10135_00335 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D NCTC10135_01199 rpsF; ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D NCTC10135_00226 rpS7_1; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D NCTC10135_00332 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D NCTC10135_00620 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D NCTC10135_00312 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D NCTC10135_00225 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D NCTC10135_00344 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D NCTC10135_00331 rpsN; ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D NCTC10135_00615 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D NCTC10135_00393 rpsP; ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D NCTC10135_00326 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D NCTC10135_01196 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D NCTC10135_00804 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D NCTC10135_00427 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D NCTC10135_00319 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D NCTC10135_00313 rplC_1; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D NCTC10135_00316 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D NCTC10135_00317 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D NCTC10135_00333 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D NCTC10135_00258 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D NCTC10135_00863 rpII; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D NCTC10135_00257 rplJ; ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D NCTC10135_00428 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D NCTC10135_00621 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D NCTC10135_00327 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D NCTC10135_00336 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D NCTC10135_00348 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D NCTC10135_00334 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D NCTC10135_00395 rplS; ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D NCTC10135_00271 rplU_1; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D NCTC10135_01289 rplU_2; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D NCTC10135_00321 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D NCTC10135_00318 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D NCTC10135_00328 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D NCTC10135_00272 rpmA_1; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D NCTC10135_01290 rpmA_2; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D NCTC10135_00006 rpmB; ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D NCTC10135_00325 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D NCTC10135_00283 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D NCTC10135_00349 rpmF; ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D NCTC10135_00593 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D NCTC10135_01347 rpmH; ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D NCTC10135_00962 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
C 00970 Aminoacyl-tRNA biosynthesis [PATH:mala00970]
D NCTC10135_00432 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D NCTC10135_00730 tRNA-His K14226 tRNA-His; tRNA His
D NCTC10135_00619 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D NCTC10135_00208 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D NCTC10135_01241 gatA_2; aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D NCTC10135_01238 MCYN0324_1; Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D NCTC10135_01242 gatC; glutamyl-tRNA(gln)amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D NCTC10135_00852 alaS_1; Alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D NCTC10135_01064 asnS_2; Asparagine--tRNA ligase K22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]
D NCTC10135_00561 lysS_2; lysyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D NCTC10135_01063 asnS_1; Asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D NCTC10135_00798 thrS_2; Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D NCTC10135_00799 thrS_3; Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D NCTC10135_01007 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D NCTC10135_00975 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D NCTC10135_00293 leuS_2; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D NCTC10135_00117 lysS_1; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D NCTC10135_01102 proS_1; Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D NCTC10135_00560 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D NCTC10135_01193 pheS; phenylalanyl-tRNA synthetase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D NCTC10135_01189 pheT_1; Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D NCTC10135_00400 tyrS_2; tyrosyl tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D NCTC10135_00795 trpS_2; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:mala03060]
D NCTC10135_00564 Uncharacterised protein K03075 secG; preprotein translocase subunit SecG
D NCTC10135_01343 putative inner membrane protein translocase component YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D NCTC10135_00819 secA_2; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D NCTC10135_00607 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D NCTC10135_01042 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:mala04122]
D NCTC10135_00855 mnmA_1; tRNA-specific 2-thiouridylase mnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D NCTC10135_00856 mnmA_2; tRNA-specific 2-thiouridylase mnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D NCTC10135_00894 thiI; thiamine biosynthesis protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
C 03050 Proteasome
C 03018 RNA degradation [PATH:mala03018]
D NCTC10135_00425 eno_2; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NCTC10135_00426 eno_3; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NCTC10135_00565 vacB; VacB-like exoribonuclease II K12573 rnr; ribonuclease R [EC:3.1.13.1]
D NCTC10135_00018 metallo-beta-lactamase superfamily protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D NCTC10135_01133 rnjB_2; hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-]
D NCTC10135_01173 dnaK_1; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:mala03030]
D NCTC10135_01033 polC_6; DNA polymerase III polC-type K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D NCTC10135_00936 dnaE_2; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D NCTC10135_00812 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D NCTC10135_00806 holB; DNA polymerase III subunit delta K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D NCTC10135_00584 holA; DNA-directed DNA polymerase K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D NCTC10135_00004 dnaN_2; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D NCTC10135_00668 dnaB_1; Replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D NCTC10135_00714 dnaB_2; Replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D NCTC10135_00715 dnaC_1; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D NCTC10135_00861 dnaC_2; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D NCTC10135_00862 dnaC_3; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D NCTC10135_01198 ssb_3; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D NCTC10135_01200 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D NCTC10135_00578 lig_1; NAD(+)-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03410 Base excision repair [PATH:mala03410]
D NCTC10135_00976 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D NCTC10135_01306 mutM; Foramidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D NCTC10135_00597 nfo; putative endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D NCTC10135_00578 lig_1; NAD(+)-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:mala03420]
D NCTC10135_00457 cbiO_2; cobalt ABC transporter ATP-binding protein K03701 uvrA; excinuclease ABC subunit A
D NCTC10135_01128 uvrB_1; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
D NCTC10135_00434 uvrC_1; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
D NCTC10135_00435 uvrC_2; Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
D NCTC10135_01059 pcrA_3; ATP-dependent DNA helicase UvrD/PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D NCTC10135_00578 lig_1; NAD(+)-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03430 Mismatch repair [PATH:mala03430]
D NCTC10135_01059 pcrA_3; ATP-dependent DNA helicase UvrD/PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D NCTC10135_01198 ssb_3; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D NCTC10135_00936 dnaE_2; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D NCTC10135_00004 dnaN_2; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D NCTC10135_00812 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D NCTC10135_00584 holA; DNA-directed DNA polymerase K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D NCTC10135_00806 holB; DNA polymerase III subunit delta K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D NCTC10135_01033 polC_6; DNA polymerase III polC-type K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D NCTC10135_00578 lig_1; NAD(+)-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03440 Homologous recombination [PATH:mala03440]
D NCTC10135_01198 ssb_3; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D NCTC10135_00013 recO; recombinational DNA repair protein O K03584 recO; DNA repair protein RecO (recombination protein O)
D NCTC10135_00809 recR; Recombination protein recR K06187 recR; recombination protein RecR
D NCTC10135_01187 recA_1; recombinase protein, RecA K03553 recA; recombination protein RecA
D NCTC10135_01188 recA_2; Recombinase A K03553 recA; recombination protein RecA
D NCTC10135_00554 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D NCTC10135_00556 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D NCTC10135_00936 dnaE_2; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D NCTC10135_00004 dnaN_2; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D NCTC10135_00812 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D NCTC10135_00584 holA; DNA-directed DNA polymerase K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D NCTC10135_00806 holB; DNA polymerase III subunit delta K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D NCTC10135_01033 polC_6; DNA polymerase III polC-type K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
C 03450 Non-homologous end-joining
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:mala02010]
D NCTC10135_01070 potB; polyamine (spermidine/putrescine) ABC transporter permease K11071 potB; spermidine/putrescine transport system permease protein
D NCTC10135_00827 malK_2; maltodextrin ABC transporter ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D NCTC10135_00927 phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein K02044 phnD; phosphonate transport system substrate-binding protein
D NCTC10135_00091 metN; ABC transporter ATP-binding protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D NCTC10135_00090 yheH; ABC transporter ATP-binding protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D NCTC10135_00925 phnC; ABC transporter ATP-binding protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D NCTC10135_00357 oppB_1; oligopeptide ABC transporter permease K15581 oppB; oligopeptide transport system permease protein
D NCTC10135_00503 oppB_2; oligopeptide ABC transporter permease K15581 oppB; oligopeptide transport system permease protein
D NCTC10135_00366 Uncharacterised protein K10823 oppF; oligopeptide transport system ATP-binding protein
D NCTC10135_00367 pstB; phosphate ABC transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein
D NCTC10135_00577 ecfT; Energy-coupling factor transporter transmembrane protein EcfT K16785 ecfT; energy-coupling factor transport system permease protein
D NCTC10135_00575 cbiO1; Cobalt import ATP-binding protein cbiO 1 K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D NCTC10135_00576 cbiO_3; cobalt ABC transporter ATP-binding protein K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D NCTC10135_00125 mldB1_1; ABC-type multidrug/protein/lipid transport system ATPase component K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump
C 02060 Phosphotransferase system (PTS)
D NCTC10135_01315 yfkN; Trifunctional nucleotide phosphoesterase protein YfkN precursor K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]
C 03070 Bacterial secretion system [PATH:mala03070]
D NCTC10135_00564 Uncharacterised protein K03075 secG; preprotein translocase subunit SecG
D NCTC10135_01343 putative inner membrane protein translocase component YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D NCTC10135_00819 secA_2; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D NCTC10135_01042 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D NCTC10135_00607 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:mala02020]
D NCTC10135_00147 Calcium-transporting ATPase lmo0841 K01547 kdpB; potassium-transporting ATPase ATP-binding subunit [EC:7.2.2.6]
D NCTC10135_00001 dnaA_1; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:mala02024]
D NCTC10135_01074 MCYN0077_1; ABC-type maltose/maltodextrin transporter ATP-binding protein MalK K02052 ABC.SP.A; putative spermidine/putrescine transport system ATP-binding protein
D NCTC10135_00357 oppB_1; oligopeptide ABC transporter permease K15581 oppB; oligopeptide transport system permease protein
D NCTC10135_00503 oppB_2; oligopeptide ABC transporter permease K15581 oppB; oligopeptide transport system permease protein
D NCTC10135_00366 Uncharacterised protein K10823 oppF; oligopeptide transport system ATP-binding protein
D NCTC10135_00367 pstB; phosphate ABC transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein
D NCTC10135_00365 cbiO_1; cobalt transporter ATP-binding subunit K02032 ddpF; peptide/nickel transport system ATP-binding protein
D NCTC10135_01343 putative inner membrane protein translocase component YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D NCTC10135_00564 Uncharacterised protein K03075 secG; preprotein translocase subunit SecG
D NCTC10135_00819 secA_2; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D NCTC10135_01042 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D NCTC10135_00607 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly
D NCTC10135_00598 rpoD_1; RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D NCTC10135_00425 eno_2; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NCTC10135_00426 eno_3; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance
D NCTC10135_00357 oppB_1; oligopeptide ABC transporter permease K15581 oppB; oligopeptide transport system permease protein
D NCTC10135_00503 oppB_2; oligopeptide ABC transporter permease K15581 oppB; oligopeptide transport system permease protein
D NCTC10135_00366 Uncharacterised protein K10823 oppF; oligopeptide transport system ATP-binding protein
D NCTC10135_00367 pstB; phosphate ABC transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein
C 01502 Vancomycin resistance
C 01503 Cationic antimicrobial peptide (CAMP) resistance
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:mala01000]
C 01001 Protein kinases [BR:mala01001]
D NCTC10135_00969 prkC; serine/threonine protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
C 01009 Protein phosphatases and associated proteins
C 01002 Peptidases and inhibitors [BR:mala01002]
D NCTC10135_00978 pepA_2; Cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D NCTC10135_01000 ftsH_3; AAA family ATPase K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D NCTC10135_00842 ysdC; Putative aminopeptidase ysdC K20608 tet; tetrahedral aminopeptidase [EC:3.4.11.-]
D NCTC10135_01096 MCYN0354; ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D NCTC10135_00957 Periplasmic protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
C 01003 Glycosyltransferases
C 01005 Lipopolysaccharide biosynthesis proteins
C 01011 Peptidoglycan biosynthesis and degradation proteins
C 01004 Lipid biosynthesis proteins [BR:mala01004]
D NCTC10135_01021 plsX_1; fatty acid/phospholipid synthesis protein PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D NCTC10135_01022 plsX_2; putative glycerol-3-phosphate acyltransferase PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D NCTC10135_01090 plsY; G3P acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D NCTC10135_01246 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:mala01006]
D NCTC10135_00064 Bacterial protein of uncharacterised function (DUF885) K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 01007 Amino acid related enzymes [BR:mala01007]
D NCTC10135_00400 tyrS_2; tyrosyl tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D NCTC10135_00795 trpS_2; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D NCTC10135_00293 leuS_2; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D NCTC10135_00117 lysS_1; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D NCTC10135_01064 asnS_2; Asparagine--tRNA ligase K22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]
D NCTC10135_01063 asnS_1; Asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D NCTC10135_00561 lysS_2; lysyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D NCTC10135_00560 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D NCTC10135_01007 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D NCTC10135_01102 proS_1; Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D NCTC10135_00798 thrS_2; Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D NCTC10135_00799 thrS_3; Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D NCTC10135_00852 alaS_1; Alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D NCTC10135_01193 pheS; phenylalanyl-tRNA synthetase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D NCTC10135_01189 pheT_1; Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:mala00194]
D NCTC10135_00743 atpC; ATP synthase subunit epsilon K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D NCTC10135_00276 atpD-2; ATP synthase F1 subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D NCTC10135_00744 atpD; ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D NCTC10135_00745 MCYN0314; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D NCTC10135_00274 atpA_1; ATP synthase F0F1 subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D NCTC10135_00748 atpH; F0F1 ATP synthase subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D NCTC10135_00749 atpF; ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D NCTC10135_00750 atpE; ATP synthase subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D NCTC10135_00751 F0F1 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:mala03000]
D NCTC10135_01126 Uncharacterised protein K03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor
D NCTC10135_01091 hrcA; heat inducible transcription repressor HrcA K03705 hrcA; heat-inducible transcriptional repressor
D NCTC10135_00626 mraZ; Protein mraZ K03925 mraZ; transcriptional regulator MraZ
C 03021 Transcription machinery [BR:mala03021]
D NCTC10135_00346 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D NCTC10135_00262 rpoB_4; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D NCTC10135_00600 Uncharacterised protein K03048 rpoE; DNA-directed RNA polymerase subunit delta
D NCTC10135_00598 rpoD_1; RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor
D NCTC10135_00137 nusA; Transcription elongation protein nusA K02600 nusA; transcription termination/antitermination protein NusA
D NCTC10135_00846 greA; transcription elongation factor GreA K03624 greA; transcription elongation factor GreA
D NCTC10135_00269 rpoC_4; DNA-directed RNA polymerase subunit beta' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D NCTC10135_00261 rpoB_3; DNA-directed RNA polymerase subunit beta K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
C 03019 Messenger RNA biogenesis [BR:mala03019]
D NCTC10135_01024 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D NCTC10135_00018 metallo-beta-lactamase superfamily protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D NCTC10135_01133 rnjB_2; hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-]
D NCTC10135_00565 vacB; VacB-like exoribonuclease II K12573 rnr; ribonuclease R [EC:3.1.13.1]
D NCTC10135_00425 eno_2; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NCTC10135_00426 eno_3; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NCTC10135_01173 dnaK_1; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
C 03041 Spliceosome
C 03011 Ribosome [BR:mala03011]
D NCTC10135_00042 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D NCTC10135_00322 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D NCTC10135_00447 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D NCTC10135_00335 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D NCTC10135_01199 rpsF; ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D NCTC10135_00226 rpS7_1; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D NCTC10135_00332 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D NCTC10135_00620 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D NCTC10135_00312 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D NCTC10135_00225 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D NCTC10135_00344 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D NCTC10135_00331 rpsN; ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D NCTC10135_00615 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D NCTC10135_00393 rpsP; ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D NCTC10135_00326 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D NCTC10135_01196 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D NCTC10135_00804 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D NCTC10135_00427 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D NCTC10135_00319 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D NCTC10135_00313 rplC_1; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D NCTC10135_00316 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D NCTC10135_00317 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D NCTC10135_00333 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D NCTC10135_00863 rpII; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D NCTC10135_00257 rplJ; ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D NCTC10135_00428 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D NCTC10135_00258 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D NCTC10135_00621 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D NCTC10135_00327 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D NCTC10135_00336 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D NCTC10135_00348 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D NCTC10135_00334 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D NCTC10135_00395 rplS; ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D NCTC10135_00271 rplU_1; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D NCTC10135_01289 rplU_2; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D NCTC10135_00321 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D NCTC10135_00318 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D NCTC10135_00328 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D NCTC10135_00272 rpmA_1; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D NCTC10135_01290 rpmA_2; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D NCTC10135_00006 rpmB; ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D NCTC10135_00325 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D NCTC10135_00283 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D NCTC10135_00349 rpmF; ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D NCTC10135_00593 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D NCTC10135_01347 rpmH; ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D NCTC10135_00962 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
C 03009 Ribosome biogenesis [BR:mala03009]
D NCTC10135_01024 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D NCTC10135_00515 der; GTP-binding protein Der K03595 era; GTPase
D NCTC10135_01079 era; GTP-binding Era-like protein K03595 era; GTPase
D NCTC10135_00200 obg; GTPase obg K03979 obgE; GTPase [EC:3.6.5.-]
D NCTC10135_00137 nusA; Transcription elongation protein nusA K02600 nusA; transcription termination/antitermination protein NusA
D NCTC10135_00869 rsuA; 16S rRNA uridine-516 pseudouridylate synthaseand related pseudouridylate synthase K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]
D NCTC10135_00009 ksgA; dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D NCTC10135_00971 rsmD; DNA methylase K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]
D NCTC10135_00622 rsmE; 16S ribosomal RNA methyltransferase RsmE K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]
D NCTC10135_00096 gidB1; glucose-inhibited division protein B K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D NCTC10135_00704 Uncharacterised protein K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D NCTC10135_00625 mraW_2; S-adenosyl-methyltransferase K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D NCTC10135_00805 rsmI; putative SAM-dependent methyltransferase K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]
D NCTC10135_01183 ftsJ; predicted 23S rRNA methylase K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]
D NCTC10135_00027 SpoU rRNA methylase family protein domain-containing protein K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]
D NCTC10135_00129 MCYN0591; Ribosomal RNA large subunit methyltransferase H K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]
D NCTC10135_00537 rluB_1; ribosomal large subunit pseudouridine synthase B K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]
D NCTC10135_00538 rluB_2; ribosomal large subunit pseudouridine synthase B K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]
D NCTC10135_01243 rluC; ribosomal large subunit pseudouridine synthase C K06179 rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24]
D NCTC10135_00213 rluD; ribosomal large subunit pseudouridine synthase D K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D NCTC10135_00850 yqgFc; putative Holliday junction resolvase K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
D NCTC10135_00968 engC; GTPase YjeQ/EngC K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
D NCTC10135_00612 rbgA_2; GTPase K14540 rbgA; ribosome biogenesis GTPase A
D NCTC10135_00132 rbfA; Ribosome-binding factor A K02834 rbfA; ribosome-binding factor A
D NCTC10135_00005 yaaA; s4-like RNA-binding protein K14761 rlbA; ribosome-associated protein
D NCTC10135_01080 conserved hypothetical metalloprotease K07042 ybeY; probable rRNA maturation factor
D NCTC10135_00728 engD_3; GTP-binding and nucleic acid-binding protein YchF K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:mala03016]
D NCTC10135_01102 proS_1; Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D NCTC10135_00293 leuS_2; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D NCTC10135_00117 lysS_1; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D NCTC10135_01064 asnS_2; Asparagine--tRNA ligase K22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]
D NCTC10135_00852 alaS_1; Alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D NCTC10135_01063 asnS_1; Asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D NCTC10135_00798 thrS_2; Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D NCTC10135_00799 thrS_3; Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D NCTC10135_01007 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D NCTC10135_00560 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D NCTC10135_01193 pheS; phenylalanyl-tRNA synthetase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D NCTC10135_01189 pheT_1; Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D NCTC10135_00400 tyrS_2; tyrosyl tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D NCTC10135_00795 trpS_2; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D NCTC10135_00116 HINT (histidine triad nucleotide-binding protein) family member K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D NCTC10135_00987 trmB_1; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D NCTC10135_00988 trmB_2; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D NCTC10135_00373 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D NCTC10135_01047 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D NCTC10135_00130 gidA_1; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D NCTC10135_00561 lysS_2; lysyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D NCTC10135_00394 trmD; tRNA (guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D NCTC10135_00613 trmL; TrmH family RNA methyltransferase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D NCTC10135_00190 yfiC; DNA methylase K15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223]
D NCTC10135_00855 mnmA_1; tRNA-specific 2-thiouridylase mnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D NCTC10135_00856 mnmA_2; tRNA-specific 2-thiouridylase mnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D NCTC10135_00894 thiI; thiamine biosynthesis protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D NCTC10135_01002 tilS; tRNA(Ile)-lysidine synthase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D NCTC10135_00904 ydiB; ATPase or kinase K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D NCTC10135_00139 cytidyltransferase-like domain K27343 tmcAL; tRNA(Met) cytidine acetate ligase [EC:6.3.4.-]
D NCTC10135_00565 vacB; VacB-like exoribonuclease II K12573 rnr; ribonuclease R [EC:3.1.13.1]
C 03012 Translation factors [BR:mala03012]
D NCTC10135_00133 infB_1; translation initiation factor if-2 K02519 infB; translation initiation factor IF-2
D NCTC10135_00135 infB_2; translation initiation factor if-2 K02519 infB; translation initiation factor IF-2
D NCTC10135_00963 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D NCTC10135_00044 tsf_2; Elongation factor Ts K02357 tsf; elongation factor Ts
D NCTC10135_00045 tsf_3; Elongation factor Ts K02357 tsf; elongation factor Ts
D NCTC10135_00498 tufA; elongation factor Tu K02358 tuf; elongation factor Tu
D NCTC10135_00229 lepA_4; GTP-binding protein lepA K02355 fusA; elongation factor G
D NCTC10135_00230 fusA_2; Elongation factor G domain protein K02355 fusA; elongation factor G
D NCTC10135_00154 lepA_1; GTP-binding protein lepA K03833 selB; selenocysteine-specific elongation factor
D NCTC10135_00526 prfA; Peptide chain release factor 1 K02835 prfA; peptide chain release factor 1
D NCTC10135_01037 frr_1; ribosome recycling factor K02838 frr; ribosome recycling factor
D NCTC10135_00525 hemK; protoporphyrinogen oxidase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D NCTC10135_01003 pth; peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D NCTC10135_00343 infA; translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1
D NCTC10135_00545 efp; elongation factor P K02356 efp; elongation factor P
C 03110 Chaperones and folding catalysts [BR:mala03110]
D NCTC10135_01173 dnaK_1; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D NCTC10135_00524 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D NCTC10135_01093 grpE; heat shock protein GrpE K03687 GRPE; molecular chaperone GrpE
D NCTC10135_01000 ftsH_3; AAA family ATPase K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D NCTC10135_00751 F0F1 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D NCTC10135_01101 trxA; thioredoxin K03671 TXN; thioredoxin
C 04131 Membrane trafficking [BR:mala04131]
D NCTC10135_01097 gap_1; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D NCTC10135_01115 pyk_1; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D NCTC10135_01116 pyk_2; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
C 04121 Ubiquitin system
C 03051 Proteasome
C 03032 DNA replication proteins [BR:mala03032]
D NCTC10135_00511 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D NCTC10135_00001 dnaA_1; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D NCTC10135_00668 dnaB_1; Replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D NCTC10135_00714 dnaB_2; Replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D NCTC10135_00715 dnaC_1; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D NCTC10135_00861 dnaC_2; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D NCTC10135_00862 dnaC_3; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D NCTC10135_01198 ssb_3; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D NCTC10135_00936 dnaE_2; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D NCTC10135_00004 dnaN_2; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D NCTC10135_00584 holA; DNA-directed DNA polymerase K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D NCTC10135_00806 holB; DNA polymerase III subunit delta K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D NCTC10135_01033 polC_6; DNA polymerase III polC-type K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D NCTC10135_00812 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D NCTC10135_01200 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D NCTC10135_00578 lig_1; NAD(+)-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D NCTC10135_00986 gyrA_3; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D NCTC10135_01142 gyrB_6; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D NCTC10135_00885 gyrA_1; DNA gyrase subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D NCTC10135_00890 gyrB_3; DNA gyrase subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D NCTC10135_00521 topA_1; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:mala03036]
D NCTC10135_01024 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D NCTC10135_00511 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D NCTC10135_00001 dnaA_1; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D NCTC10135_01016 smc; ABC transporter ATP-binding protein K03529 smc; chromosome segregation protein
D NCTC10135_01245 scpA; segregation and condensation protein A K05896 scpA; segregation and condensation protein A
D NCTC10135_01244 scpB; segregation and condensation protein B K06024 scpB; segregation and condensation protein B
D NCTC10135_00623 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D NCTC10135_01175 dnaK_3; chaperone protein DnaK K03569 mreB; rod shape-determining protein MreB and related proteins
D NCTC10135_00885 gyrA_1; DNA gyrase subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D NCTC10135_00890 gyrB_3; DNA gyrase subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D NCTC10135_00130 gidA_1; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D NCTC10135_00096 gidB1; glucose-inhibited division protein B K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D NCTC10135_00704 Uncharacterised protein K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D NCTC10135_00907 engB; ribosome biogenesis GTP-binding protein YsxC K03978 engB; GTP-binding protein
D NCTC10135_00119 Uncharacterized protein conserved in bacteria K09762 whiA; cell division protein WhiA
C 03400 DNA repair and recombination proteins [BR:mala03400]
D NCTC10135_00976 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D NCTC10135_01306 mutM; Foramidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D NCTC10135_00597 nfo; putative endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D NCTC10135_00578 lig_1; NAD(+)-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D NCTC10135_00457 cbiO_2; cobalt ABC transporter ATP-binding protein K03701 uvrA; excinuclease ABC subunit A
D NCTC10135_01128 uvrB_1; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
D NCTC10135_00434 uvrC_1; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
D NCTC10135_00435 uvrC_2; Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
D NCTC10135_01059 pcrA_3; ATP-dependent DNA helicase UvrD/PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D NCTC10135_00262 rpoB_4; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D NCTC10135_00346 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D NCTC10135_00600 Uncharacterised protein K03048 rpoE; DNA-directed RNA polymerase subunit delta
D NCTC10135_00936 dnaE_2; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D NCTC10135_00004 dnaN_2; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D NCTC10135_00584 holA; DNA-directed DNA polymerase K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D NCTC10135_00806 holB; DNA polymerase III subunit delta K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D NCTC10135_01033 polC_6; DNA polymerase III polC-type K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D NCTC10135_00812 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D NCTC10135_01198 ssb_3; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D NCTC10135_01187 recA_1; recombinase protein, RecA K03553 recA; recombination protein RecA
D NCTC10135_01188 recA_2; Recombinase A K03553 recA; recombination protein RecA
D NCTC10135_00554 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D NCTC10135_00556 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D NCTC10135_00013 recO; recombinational DNA repair protein O K03584 recO; DNA repair protein RecO (recombination protein O)
D NCTC10135_00809 recR; Recombination protein recR K06187 recR; recombination protein RecR
D NCTC10135_00510 prfA2; penicillin-binding protein-related factor A recombinase K03700 recU; recombination protein U
D NCTC10135_00986 gyrA_3; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D NCTC10135_01142 gyrB_6; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D NCTC10135_00521 topA_1; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D NCTC10135_00511 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D NCTC10135_01179 dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D NCTC10135_00920 Predicted phosphohydrolase (DHH superfamily) K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
D NCTC10135_01309 nrnA; Bifunctional oligoribonuclease and PAP phosphatase nrnA K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
C 03029 Mitochondrial biogenesis [BR:mala03029]
D NCTC10135_00133 infB_1; translation initiation factor if-2 K02519 infB; translation initiation factor IF-2
D NCTC10135_00135 infB_2; translation initiation factor if-2 K02519 infB; translation initiation factor IF-2
D NCTC10135_00963 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D NCTC10135_00044 tsf_2; Elongation factor Ts K02357 tsf; elongation factor Ts
D NCTC10135_00045 tsf_3; Elongation factor Ts K02357 tsf; elongation factor Ts
D NCTC10135_00498 tufA; elongation factor Tu K02358 tuf; elongation factor Tu
D NCTC10135_00229 lepA_4; GTP-binding protein lepA K02355 fusA; elongation factor G
D NCTC10135_00230 fusA_2; Elongation factor G domain protein K02355 fusA; elongation factor G
D NCTC10135_00156 lepA_3; GTP-binding protein lepA K21594 GUF1; translation factor GUF1, mitochondrial [EC:3.6.5.-]
D NCTC10135_00515 der; GTP-binding protein Der K03595 era; GTPase
D NCTC10135_01079 era; GTP-binding Era-like protein K03595 era; GTPase
D NCTC10135_00400 tyrS_2; tyrosyl tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D NCTC10135_00293 leuS_2; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D NCTC10135_01241 gatA_2; aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D NCTC10135_01238 MCYN0324_1; Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D NCTC10135_01242 gatC; glutamyl-tRNA(gln)amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D NCTC10135_01198 ssb_3; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D NCTC10135_00081 Uncharacterised protein K22830 SMDT1; essential MCU regulator, mitochondrial
D NCTC10135_01173 dnaK_1; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D NCTC10135_01093 grpE; heat shock protein GrpE K03687 GRPE; molecular chaperone GrpE
D NCTC10135_00524 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D NCTC10135_01343 putative inner membrane protein translocase component YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:mala02000]
D NCTC10135_00125 mldB1_1; ABC-type multidrug/protein/lipid transport system ATPase component K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump
D NCTC10135_01070 potB; polyamine (spermidine/putrescine) ABC transporter permease K11071 potB; spermidine/putrescine transport system permease protein
D NCTC10135_01074 MCYN0077_1; ABC-type maltose/maltodextrin transporter ATP-binding protein MalK K02052 ABC.SP.A; putative spermidine/putrescine transport system ATP-binding protein
D NCTC10135_00827 malK_2; maltodextrin ABC transporter ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D NCTC10135_00927 phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein K02044 phnD; phosphonate transport system substrate-binding protein
D NCTC10135_00091 metN; ABC transporter ATP-binding protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D NCTC10135_00090 yheH; ABC transporter ATP-binding protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D NCTC10135_00925 phnC; ABC transporter ATP-binding protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D NCTC10135_00062 Basic membrane protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D NCTC10135_00357 oppB_1; oligopeptide ABC transporter permease K15581 oppB; oligopeptide transport system permease protein
D NCTC10135_00503 oppB_2; oligopeptide ABC transporter permease K15581 oppB; oligopeptide transport system permease protein
D NCTC10135_00366 Uncharacterised protein K10823 oppF; oligopeptide transport system ATP-binding protein
D NCTC10135_00367 pstB; phosphate ABC transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein
D NCTC10135_00365 cbiO_1; cobalt transporter ATP-binding subunit K02032 ddpF; peptide/nickel transport system ATP-binding protein
D NCTC10135_00123 Uncharacterised protein K16926 htsT; energy-coupling factor transport system substrate-specific component
D NCTC10135_00577 ecfT; Energy-coupling factor transporter transmembrane protein EcfT K16785 ecfT; energy-coupling factor transport system permease protein
D NCTC10135_00575 cbiO1; Cobalt import ATP-binding protein cbiO 1 K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D NCTC10135_00576 cbiO_3; cobalt ABC transporter ATP-binding protein K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D NCTC10135_00083 High affinity transport system protein p37 K01992 ABC-2.P; ABC-2 type transport system permease protein
D NCTC10135_00105 FtsX-like permease family K01992 ABC-2.P; ABC-2 type transport system permease protein
D NCTC10135_00338 secY_1; preprotein translocase subunit SecY K01992 ABC-2.P; ABC-2 type transport system permease protein
D NCTC10135_01168 abc; ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D NCTC10135_00106 macB; ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D NCTC10135_01315 yfkN; Trifunctional nucleotide phosphoesterase protein YfkN precursor K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]
D NCTC10135_00021 mscL; large conductance mechanosensitive channel protein K03282 mscL; large conductance mechanosensitive channel
D NCTC10135_01157 oligoendopeptidase F K03559 exbD; biopolymer transport protein ExbD
D NCTC10135_01222 ktrB_2; Ktr system potassium uptake protein B K03498 trkH; trk/ktr system potassium uptake protein
D NCTC10135_01249 ktrA; Potassium uptake protein KtrA K03499 trkA; trk/ktr system potassium uptake protein
D NCTC10135_00209 Uncharacterised protein K15383 K15383; MtN3 and saliva related transmembrane protein
D NCTC10135_00210 Uncharacterised protein K15383 K15383; MtN3 and saliva related transmembrane protein
C 02044 Secretion system [BR:mala02044]
D NCTC10135_00582 Uncharacterised protein K02237 comEA; competence protein ComEA
D NCTC10135_01027 polC_1; DNA polymerase III polC-type K02237 comEA; competence protein ComEA
D NCTC10135_00580 ComEC/Rec2-related protein K02238 comEC; competence protein ComEC
D NCTC10135_00819 secA_2; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D NCTC10135_00564 Uncharacterised protein K03075 secG; preprotein translocase subunit SecG
D NCTC10135_00607 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D NCTC10135_01042 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D NCTC10135_01343 putative inner membrane protein translocase component YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
C 02042 Bacterial toxins [BR:mala02042]
C 02022 Two-component system
C 02035 Bacterial motility proteins
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:mala04812]
D NCTC10135_01175 dnaK_3; chaperone protein DnaK K03569 mreB; rod shape-determining protein MreB and related proteins
D NCTC10135_00623 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
C 04147 Exosome [BR:mala04147]
D NCTC10135_00425 eno_2; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NCTC10135_00426 eno_3; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NCTC10135_01097 gap_1; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D NCTC10135_00672 pgk_1; Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D NCTC10135_01115 pyk_1; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D NCTC10135_01116 pyk_2; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D NCTC10135_01173 dnaK_1; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D NCTC10135_00498 tufA; elongation factor Tu K02358 tuf; elongation factor Tu
D NCTC10135_00116 HINT (histidine triad nucleotide-binding protein) family member K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D NCTC10135_00088 ldh_1; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
D NCTC10135_00341 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D NCTC10135_01156 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D NCTC10135_01319 pdhD; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D NCTC10135_00369 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 02048 Prokaryotic defense system [BR:mala02048]
D NCTC10135_00166 Type I restriction modification DNA specificity domain K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D NCTC10135_00182 Uncharacterised protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D NCTC10135_00161 Type I restriction-modification system methyltransferase subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D NCTC10135_00162 bcgIA; Restriction enzyme BgcI subunit alpha K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D NCTC10135_00163 Probable type I restriction enzyme BthVORF4518P M protein K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D NCTC10135_00623 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D NCTC10135_01175 dnaK_3; chaperone protein DnaK K03569 mreB; rod shape-determining protein MreB and related proteins
D NCTC10135_00885 gyrA_1; DNA gyrase subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D NCTC10135_00890 gyrB_3; DNA gyrase subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes [BR:mala01504]
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:mala03100]
D NCTC10135_00432 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D NCTC10135_00730 tRNA-His K14226 tRNA-His; tRNA His
D NCTC10135_00619 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D NCTC10135_00208 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D NCTC10135_00430 azoR; FMN-dependent NADH-azoreductase K01118 acpD; FMN-dependent NADH-azoreductase [EC:1.7.1.17]
D NCTC10135_00741 msrA; peptide-methionine (S)-S-oxide reductase K12267 msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12]
D NCTC10135_00980 Uncharacterised protein K21935 ablB; beta-lysine N6-acetyltransferase [EC:2.3.1.264]
D NCTC10135_01020 kinase K07030 fakA; fatty acid kinase [EC:2.7.2.18]
D NCTC10135_00865 putative bifunctional signaling protein/50S ribosomal protein L9 K22927 gdpP; cyclic-di-AMP phosphodiesterase [EC:3.1.4.59]
D NCTC10135_00008 tatD; TatD DNase family protein K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D NCTC10135_00035 Staphylococcal nuclease homologue K01174 nuc; micrococcal nuclease [EC:3.1.31.1]
D NCTC10135_00783 def; formylmethionine deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D NCTC10135_00093 mgtA_2; Magnesium-transporting ATPase, P-type 1 K01531 mgtA; P-type Mg2+ transporter [EC:7.2.2.14]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
D NCTC10135_01180 nifU; Aminotransferase U-like protein K04488 iscU; nitrogen fixation protein NifU and related proteins
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
D NCTC10135_01291 Uncharacterised protein K01449 cwlJ; cell wall hydrolase
C 99987 Cofactor metabolism
C 99988 Secondary metabolism
C 99999 Others
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D NCTC10135_00138 yhgF; RNA (S1 domain)-binding protein K06959 tex; protein Tex
C 99974 Translation
C 99975 Protein processing
D NCTC10135_00421 MCYN0725; Trigger factor K03545 tig; trigger factor
D NCTC10135_00566 smpB; SsrA-binding protein K03664 smpB; SsrA-binding protein
C 99976 Replication and repair
D NCTC10135_00496 RmuC family K09760 rmuC; DNA recombination protein RmuC
D NCTC10135_00048 Transposase and inactivated derivatives, IS30 family K07482 K07482; transposase, IS30 family
D NCTC10135_00049 transposase K07482 K07482; transposase, IS30 family
D NCTC10135_00231 transposase K07482 K07482; transposase, IS30 family
D NCTC10135_00232 Transposase and inactivated derivatives, IS30 family K07482 K07482; transposase, IS30 family
D NCTC10135_00591 transposase K07482 K07482; transposase, IS30 family
D NCTC10135_00592 Transposase and inactivated derivatives, IS30 family K07482 K07482; transposase, IS30 family
D NCTC10135_00596 Transposase and inactivated derivatives, IS30 family K07482 K07482; transposase, IS30 family
D NCTC10135_00633 Transposase and inactivated derivatives, IS30 family K07482 K07482; transposase, IS30 family
D NCTC10135_00634 transposase K07482 K07482; transposase, IS30 family
D NCTC10135_00681 Transposase and inactivated derivatives, IS30 family K07482 K07482; transposase, IS30 family
D NCTC10135_00682 transposase K07482 K07482; transposase, IS30 family
D NCTC10135_00771 Transposase and inactivated derivatives, IS30 family K07482 K07482; transposase, IS30 family
D NCTC10135_00910 Transposase and inactivated derivatives, IS30 family K07482 K07482; transposase, IS30 family
D NCTC10135_00911 transposase K07482 K07482; transposase, IS30 family
D NCTC10135_01223 Transposase and inactivated derivatives, IS30 family K07482 K07482; transposase, IS30 family
D NCTC10135_01224 transposase K07482 K07482; transposase, IS30 family
D NCTC10135_01265 Transposase and inactivated derivatives, IS30 family K07482 K07482; transposase, IS30 family
D NCTC10135_01266 transposase K07482 K07482; transposase, IS30 family
D NCTC10135_01301 Transposase and inactivated derivatives, IS30 family K07482 K07482; transposase, IS30 family
D NCTC10135_01302 transposase K07482 K07482; transposase, IS30 family
C 99979 Viral proteins
C 99998 Others
D NCTC10135_00810 MCYN0834; UPF0133 protein MALL_0399 K09747 ebfC; nucleoid-associated protein EbfC
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
C 99978 Cell growth
C 99993 Cell motility
C 99995 Signaling proteins
C 99992 Structural proteins
C 99994 Others
B
B 09194 Poorly characterized
C 99996 General function prediction only
D NCTC10135_01140 LemA family K03744 lemA; LemA protein
C 99997 Function unknown
D NCTC10135_01125 Uncharacterised protein K07005 K07005; uncharacterized protein
D NCTC10135_00954 putative ATPase, AAA+ superfamily K07133 K07133; uncharacterized protein
D NCTC10135_01110 Uncharacterised protein K07133 K07133; uncharacterized protein
D NCTC10135_00562 aspartyl-tRNA synthetase K07158 K07158; uncharacterized protein
D NCTC10135_01041 sigma-70 factor-like HTH protein K09787 K09787; uncharacterized protein
D NCTC10135_00813 Uncharacterised protein K09940 K09940; uncharacterized protein
D NCTC10135_00160 transmembrane protein K09976 K09976; uncharacterized protein
D NCTC10135_00136 putative transcription termination factor K07742 ylxR; uncharacterized protein
!
#
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: June 24, 2024