+F Repair protein KO
#
DNA Repair and Recombination Proteins - Myxocyprinus asiaticus (Chinese sucker)
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 127455269 methylated-DNA--protein-cysteine methyltransferase isoform X1 K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 127427572 DNA oxidative demethylase ALKBH2 K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
D 127437772 alpha-ketoglutarate-dependent dioxygenase alkB homolog 3-like K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
D 127453866 activating signal cointegrator 1 complex subunit 3 K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D 127442672 CPD photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 127426306 uracil-DNA glycosylase-like isoform X1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127439622 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127422364 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127436077 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127437390 cyclin-O protein B-like isoform X1 K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]
E 127420838 cyclin-O protein B-like K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]
E 127437705 thymine DNA glycosylase, tandem duplicate 1 isoform X1 K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 127437706 G/T mismatch-specific thymine DNA glycosylase-like isoform X1 K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 127435649 G/T mismatch-specific thymine DNA glycosylase-like isoform X1 K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 127435651 G/T mismatch-specific thymine DNA glycosylase-like isoform X1 K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 127452115 DNA-3-methyladenine glycosylase-like K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 127425976 single-strand-selective monofunctional uracil-DNA glycosylase 1 K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 127424420 adenine DNA glycosylase-like K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 127414797 adenine DNA glycosylase isoform X1 K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 127414905 methyl-CpG-binding domain protein 4 isoform X1 K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E 127424743 LOW QUALITY PROTEIN: N-glycosylase/DNA lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E 127437748 endonuclease 8-like 1 K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
E 127412913 endonuclease 8-like 3 K10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]
E 127417811 LOW QUALITY PROTEIN: endonuclease 8-like 3 K10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]
E 127443964 endonuclease III-like protein 1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E 127426828 probable endonuclease 4 K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E 127434874 DNA-(apurinic or apyrimidinic site) endonuclease K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E 127423461 si:ch211-141o9.10; probable endonuclease 4 K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E 127436410 DNA-(apurinic or apyrimidinic site) endonuclease isoform X1 K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E 127414862 DNA-(apurinic or apyrimidinic site) endonuclease 2-like isoform X1 K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
E 127423788 DNA-(apurinic or apyrimidinic site) lyase 2 isoform X1 K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F 127451899 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 127415099 DNA polymerase delta subunit 2 isoform X1 K02328 POLD2; DNA polymerase delta subunit 2
F 127430626 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
F 127428716 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
F 127444007 DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
F 127444614 DNA polymerase delta subunit 4-like K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F 127430076 DNA polymerase epsilon catalytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 127455265 DNA polymerase epsilon subunit 2-like K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 127454842 DNA polymerase epsilon subunit 2-like K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 127436780 DNA polymerase epsilon subunit 3-like K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 127417580 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 127427689 DNA polymerase epsilon subunit 4-like isoform X1 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E 127432231 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 127433437 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
E 127432116 flap endonuclease 1-like K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 127440535 zgc:110269; probable flap endonuclease 1 homolog isoform X1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 127434313 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 127442312 probable flap endonuclease 1 homolog isoform X1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 127440333 DNA ligase 1-like isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 127442776 DNA ligase 1-like K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
E 127424479 DNA polymerase beta-like K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E 127415140 DNA polymerase beta K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E 127430902 LOW QUALITY PROTEIN: DNA repair protein XRCC1 K10803 XRCC1; DNA-repair protein XRCC1
E 127453118 DNA repair protein XRCC1 isoform X1 K10803 XRCC1; DNA-repair protein XRCC1
E 127454540 LOW QUALITY PROTEIN: DNA repair protein XRCC1-like K10803 XRCC1; DNA-repair protein XRCC1
E 127418285 DNA ligase 3-like K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
E 127439843 DNA ligase 3-like isoform X1 K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
D Other BER factors
E 127411484 tyrosyl-DNA phosphodiesterase 1 K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 127443800 aprataxin isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 127443785 aprataxin and PNK-like factor isoform X1 K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 127445026 aprataxin and PNK-like factor isoform X1 K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 127422455 bifunctional polynucleotide phosphatase/kinase isoform X1 K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E 127432421 high mobility group protein B1a K10802 HMGB1; high mobility group protein B1
E 127433627 high mobility group-T protein-like K10802 HMGB1; high mobility group protein B1
E 127421927 high mobility group protein B1-like K10802 HMGB1; high mobility group protein B1
E 127429712 high mobility group protein B1-like K10802 HMGB1; high mobility group protein B1
E 127443817 DNA polymerase lambda isoform X1 K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 127415588 LOW QUALITY PROTEIN: poly [ADP-ribose] polymerase 1-like K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E 127410136 poly [ADP-ribose] polymerase 1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E 127446556 protein mono-ADP-ribosyltransferase PARP3-like isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 127446771 protein mono-ADP-ribosyltransferase PARP4 isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 127440630 poly [ADP-ribose] polymerase 2 isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 127447859 protein mono-ADP-ribosyltransferase PARP4-like isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 127442272 poly [ADP-ribose] polymerase 2-like K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 127448620 protein mono-ADP-ribosyltransferase PARP3-like K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F 127414494 DNA repair protein complementing XP-C cells-like K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 127424235 DNA repair protein complementing XP-C cells homolog isoform X1 K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 127430861 UV excision repair protein RAD23 homolog B K10839 RAD23; UV excision repair protein RAD23
F 127443793 UV excision repair protein RAD23 homolog A-like K10839 RAD23; UV excision repair protein RAD23
F 127445033 RAD23 homolog A, nucleotide excision repair protein a K10839 RAD23; UV excision repair protein RAD23
F 127438502 UV excision repair protein RAD23 homolog A-like K10839 RAD23; UV excision repair protein RAD23
F 127438824 RAD23 homolog A, nucleotide excision repair protein b K10839 RAD23; UV excision repair protein RAD23
F 127428978 UV excision repair protein RAD23 homolog B-like K10839 RAD23; UV excision repair protein RAD23
F 127412873 uncharacterized protein LOC127412873 K10840 CETN2; centrin-2
F 127417892 centrin-1-like K10840 CETN2; centrin-2
E Cul4-DDB2 complex
F 127450052 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 127452336 RING-box protein 1-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 127443429 cullin-4A K10609 CUL4; cullin 4
F 127412560 cullin-4B-like K10609 CUL4; cullin 4
F 127417686 cullin-4B isoform X1 K10609 CUL4; cullin 4
F 127456167 DNA damage-binding protein 1-like K10610 DDB1; DNA damage-binding protein 1
F 127417365 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
F 127416687 DNA damage-binding protein 2-like K10140 DDB2; DNA damage-binding protein 2
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F 127426977 DNA-directed RNA polymerase II subunit RPB1-like K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 127423134 DNA-directed RNA polymerase II subunit RPB1 isoform X1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 127412629 DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 127417586 DNA-directed RNA polymerase II subunit RPB2-like K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 127437797 DNA-directed RNA polymerase II subunit RPB3-like K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 127435621 DNA-directed RNA polymerase II subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 127440914 DNA-directed RNA polymerase II subunit RPB4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 127442983 DNA-directed RNA polymerase II subunit RPB4 isoform X1 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 127438425 DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 127438862 DNA-directed RNA polymerases I, II, and III subunit RPABC1-like K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 127441362 DNA-directed RNA polymerases I, II, and III subunit RPABC1-like isoform X1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 127451303 DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 127418247 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 127412883 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 127438158 DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 127438743 DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 127456464 DNA-directed RNA polymerase II subunit RPB9-like K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 127416780 DNA-directed RNA polymerase II subunit RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 127445657 DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F 127451223 DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F 127440081 DNA-directed RNA polymerase II subunit RPB11-a K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F 127421554 DNA-directed RNA polymerase II subunit RPB11-a K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
E Cul4-CSA complex
F 127450052 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 127452336 RING-box protein 1-like K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 127443429 cullin-4A K10609 CUL4; cullin 4
F 127412560 cullin-4B-like K10609 CUL4; cullin 4
F 127417686 cullin-4B isoform X1 K10609 CUL4; cullin 4
F 127456167 DNA damage-binding protein 1-like K10610 DDB1; DNA damage-binding protein 1
F 127417365 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
F 127415168 DNA excision repair protein ERCC-8 K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F 127412257 DNA excision repair protein ERCC-6 isoform X1 K10841 ERCC6; DNA excision repair protein ERCC-6
F 127412842 UV-stimulated scaffold protein A isoform X1 K23720 UVSSA; UV-stimulated scaffold protein A
F 127450289 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 127451772 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E 127448769 general transcription and DNA repair factor IIH helicase subunit XPB K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 127422497 general transcription and DNA repair factor IIH helicase subunit XPD K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 127437644 general transcription factor IIH subunit 1-like K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 127435586 general transcription factor IIH subunit 1-like K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 127432577 general transcription factor IIH subunit 2 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 127436056 general transcription factor IIH subunit 3 isoform X1 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E 127425464 general transcription factor IIH subunit 4-like isoform X1 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 127420976 general transcription factor IIH subunit 4 isoform X1 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 127416141 general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 127439823 cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 127428559 cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 127419454 cyclin-H K06634 CCNH; cyclin H
E 127412279 CDK-activating kinase assembly factor MAT1 isoform X1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
E 127413865 CDK-activating kinase assembly factor MAT1-like K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E 127422532 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 127430263 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 127452646 replication protein A 32 kDa subunit-like K10739 RFA2; replication factor A2
E 127454418 replication protein A 32 kDa subunit-like isoform X1 K10739 RFA2; replication factor A2
E 127424932 replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
E 127420953 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D Other NER factors
E 127445015 DNA repair protein complementing XP-A cells isoform X1 K10847 XPA; DNA-repair protein complementing XP-A cells
E 127447486 DNA excision repair protein ERCC-1 K10849 ERCC1; DNA excision repair protein ERCC-1
E 127447835 DNA excision repair protein ERCC-1-like isoform X1 K10849 ERCC1; DNA excision repair protein ERCC-1
E 127426721 DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 127443427 DNA excision repair protein ERCC-5 homolog K10846 ERCC5; DNA excision repair protein ERCC-5
E 127440333 DNA ligase 1-like isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 127442776 DNA ligase 1-like K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 127427380 MMS19 nucleotide excision repair protein homolog isoform X1 K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 127422785 MMS19 nucleotide excision repair protein homolog K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 127422260 cullin-3 K03869 CUL3; cullin 3
E 127441100 cullin-3-A-like isoform X1 K03869 CUL3; cullin 3
E 127442066 cullin-3-A-like K03869 CUL3; cullin 3
E 127429487 cullin-3-like K03869 CUL3; cullin 3
E 127430301 cullin-5a K10612 CUL5; cullin 5
E 127431039 cullin-5-like isoform X1 K10612 CUL5; cullin 5
E 127422337 cullin-5 K10612 CUL5; cullin 5
E 127429222 cullin-5 isoform X1 K10612 CUL5; cullin 5
E 127431435 elongin-C-like isoform X1 K03872 ELOC; elongin-C
E 127440502 elongin-C K03872 ELOC; elongin-C
E 127442263 elongin C paralog b K03872 ELOC; elongin-C
E 127450758 elongin-B-like isoform X1 K03873 ELOB; elongin-B
E 127451369 elongin-B K03873 ELOB; elongin-B
E 127427155 elongin-B-like isoform X1 K03873 ELOB; elongin-B
E 127423024 elongin-B-like isoform X1 K03873 ELOB; elongin-B
E 127425409 elongin-A-like K15076 ELOA; elongin-A
E 127413617 elongin A, like K15076 ELOA; elongin-A
E 127421377 elongin-A-like isoform X1 K15076 ELOA; elongin-A
E 127428631 ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
E 127425599 ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
E 127420988 ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
E 127430492 ubiquitin-associated protein 2a isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 127426714 DNA mismatch repair protein Msh2-like K08735 MSH2; DNA mismatch repair protein MSH2
E 127436459 DNA mismatch repair protein Msh3-like isoform X1 K08736 MSH3; DNA mismatch repair protein MSH3
E 127411915 DNA mismatch repair protein Msh6-like K08737 MSH6; DNA mismatch repair protein MSH6
E 127414357 DNA mismatch repair protein Msh6-like K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E 127448487 PMS1 protein homolog 1 isoform X1 K10864 PMS1; DNA mismatch repair protein PMS1
E 127414212 DNA mismatch repair protein Mlh1 K08734 MLH1; DNA mismatch repair protein MLH1
E 127427174 mismatch repair endonuclease PMS2 K10858 PMS2; DNA mismatch repair protein PMS2
E 127419130 DNA mismatch repair protein Mlh3-like isoform X1 K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E 127451899 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 127415099 DNA polymerase delta subunit 2 isoform X1 K02328 POLD2; DNA polymerase delta subunit 2
E 127430626 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
E 127428716 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
E 127444007 DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
E 127444614 DNA polymerase delta subunit 4-like K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E 127422532 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 127430263 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 127452646 replication protein A 32 kDa subunit-like K10739 RFA2; replication factor A2
E 127454418 replication protein A 32 kDa subunit-like isoform X1 K10739 RFA2; replication factor A2
E 127424932 replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
E 127420953 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D RFC (replication factor C)
E 127443630 replication factor C subunit 1-like isoform X1 K10754 RFC1; replication factor C subunit 1
E 127445152 replication factor C subunit 1-like isoform X1 K10754 RFC1; replication factor C subunit 1
E 127431184 replication factor C subunit 2 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
E 127426507 replication factor C subunit 4-like K10755 RFC2_4; replication factor C subunit 2/4
E 127428123 replication factor C subunit 4-like isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
E 127429390 replication factor C subunit 2 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
E 127430505 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
E 127437916 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
E 127432393 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
E 127433503 replication factor C subunit 3-like K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E 127432231 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 127433437 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
E 127455580 exonuclease 1-like K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 127432421 high mobility group protein B1a K10802 HMGB1; high mobility group protein B1
E 127433627 high mobility group-T protein-like K10802 HMGB1; high mobility group protein B1
E 127421927 high mobility group protein B1-like K10802 HMGB1; high mobility group protein B1
E 127429712 high mobility group protein B1-like K10802 HMGB1; high mobility group protein B1
E 127440333 DNA ligase 1-like isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 127442776 DNA ligase 1-like K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 127440384 WD repeat-containing protein 76-like isoform X1 K24755 WDR76; WD repeat-containing protein 76
E 127409659 WD repeat-containing protein 76-like K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E 127422261 double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 127430403 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 127452421 nibrin-like K10867 NBN; nibrin
D BRCA1-core complex
E 127446762 BRCA1-associated RING domain protein 1-like K10683 BARD1; BRCA1-associated RING domain protein 1
E 127448491 BRCA1-associated RING domain protein 1-like K10683 BARD1; BRCA1-associated RING domain protein 1
D BRCA1-A complex
E 127431134 BRCA1-A complex subunit Abraxas 1-like isoform X1 K20774 FAM175A; BRCA1-A complex subunit Abraxas
E 127428884 BRCA1-A complex subunit Abraxas 1-like K20774 FAM175A; BRCA1-A complex subunit Abraxas
E 127431018 BRCA1-A complex subunit RAP80-like isoform X1 K20775 UIMC1; BRCA1-A complex subunit RAP80
E 127429006 BRCA1-A complex subunit RAP80-like isoform X1 K20775 UIMC1; BRCA1-A complex subunit RAP80
E 127426533 BRISC and BRCA1-A complex member 1 K20776 BABAM; BRISC and BRCA1-A complex member 1
E 127410973 BRISC and BRCA1-A complex member 2 K12173 BRE; BRCA1-A complex subunit BRE
E 127430437 lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
E 127429365 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D BRCA1-B complex
E 127422042 Fanconi anemia group J protein isoform X1 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E 127432019 DNA topoisomerase 2-binding protein 1-A-like isoform X1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
E 127434084 DNA topoisomerase 2-binding protein 1-A-like K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D BRCA1-C complex
E 127431553 DNA endonuclease RBBP8 K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]
E 127422261 double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 127430403 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 127452421 nibrin-like K10867 NBN; nibrin
D BRCA complex
E 127422162 LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein homolog K08775 BRCA2; breast cancer 2 susceptibility protein
E 127429461 breast cancer type 2 susceptibility protein isoform X1 K08775 BRCA2; breast cancer 2 susceptibility protein
E 127443827 partner and localizer of BRCA2 K10897 PALB2; partner and localizer of BRCA2
E 127409705 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 127415683 DNA repair protein RAD51 homolog 1-like K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E 127409705 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 127415683 DNA repair protein RAD51 homolog 1-like K04482 RAD51; DNA repair protein RAD51
E 127410218 DNA repair protein RAD51 homolog 2 isoform X1 K10869 RAD51L1; RAD51-like protein 1
E 127432909 DNA repair protein RAD51 homolog 3 isoform X1 K10870 RAD51L2; RAD51-like protein 2
E 127439887 DNA repair protein RAD51 homolog 4 isoform X1 K10871 RAD51L3; RAD51-like protein 3
E 127431866 DNA repair protein XRCC2-like K10879 XRCC2; DNA-repair protein XRCC2
E 127410193 DNA repair protein XRCC3-like K10880 XRCC3; DNA-repair protein XRCC3
E 127416419 DNA repair protein XRCC3 K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
E 127437217 DNA repair protein RAD52 homolog isoform X1 K10873 RAD52; DNA repair and recombination protein RAD52
E 127451593 RAD52 motif-containing protein 1 K10874 RDM1; RAD52 motif-containing protein 1
D Rad54 family proteins
E 127445897 DNA repair and recombination protein RAD54-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 127448664 DNA repair and recombination protein RAD54-like isoform X1 K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 127438323 helicase ARIP4-like isoform X1 K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E 127439060 helicase ARIP4 K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E 127454436 DNA repair and recombination protein RAD54B-like K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E 127436867 ATP-dependent DNA helicase Q1-like isoform X1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 127435462 ATP-dependent DNA helicase Q1 isoform X1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 127432325 bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN-like isoform X1 K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E 127455697 recQ-like DNA helicase BLM K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 127425538 ATP-dependent DNA helicase Q4 isoform X1 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
E 127451153 ATP-dependent DNA helicase Q5 isoform X1 K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E 127455697 recQ-like DNA helicase BLM K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 127418208 DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 127450139 DNA topoisomerase 3-alpha-like isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 127424669 recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1
E 127452083 recQ-mediated genome instability protein 2 K15365 RMI2; RecQ-mediated genome instability protein 2
D RPA (replication factor A)
E 127422532 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 127430263 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 127452646 replication protein A 32 kDa subunit-like K10739 RFA2; replication factor A2
E 127454418 replication protein A 32 kDa subunit-like isoform X1 K10739 RFA2; replication factor A2
E 127424932 replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
E 127420953 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D Protein phosphatase 4
E 127450617 serine/threonine-protein phosphatase 4 catalytic subunit B-like K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 127451455 serine/threonine-protein phosphatase 4 catalytic subunit B-like isoform X1 K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 127427407 serine/threonine-protein phosphatase 4 catalytic subunit B K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 127422805 serine/threonine-protein phosphatase 4 catalytic subunit B K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 127449340 serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 127431910 serine/threonine-protein phosphatase 4 regulatory subunit 1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 127445936 serine/threonine-protein phosphatase 4 regulatory subunit 1-like K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 127434176 serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 127418710 serine/threonine-protein phosphatase 4 regulatory subunit 2-A-like isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 127420169 serine/threonine-protein phosphatase 4 regulatory subunit 2-A isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 127445631 serine/threonine-protein phosphatase 4 regulatory subunit 2-B-like K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 127449113 serine/threonine-protein phosphatase 4 regulatory subunit 2-B-like isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 127413738 serine/threonine-protein phosphatase 4 regulatory subunit 3-like isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 127415924 serine/threonine-protein phosphatase 4 regulatory subunit 3-like K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 127410353 serine/threonine-protein phosphatase 4 regulatory subunit 3 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 127411733 serine/threonine-protein phosphatase 4 regulatory subunit 3-like K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 127409848 serine/threonine-protein phosphatase 4 regulatory subunit 4 K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
E 127416089 serine/threonine-protein phosphatase 4 regulatory subunit 4-like isoform X1 K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
D AP-5 complex
E 127426075 AP-5 complex subunit beta-1-like K19022 AP5B1; AP-5 complex subunit beta-1
E 127427852 AP-5 complex subunit beta-1-like K19022 AP5B1; AP-5 complex subunit beta-1
E 127454868 AP-5 complex subunit mu-1-like isoform X1 K19023 AP5M1; AP-5 complex subunit mu-1
E 127412084 AP-5 complex subunit sigma-1-like K19024 AP5S1; AP-5 complex subunit sigma-1
E 127414235 AP-5 complex subunit sigma-1-like K19024 AP5S1; AP-5 complex subunit sigma-1
E 127450176 AP-5 complex subunit zeta-1-like isoform X1 K19025 AP5Z1; AP-5 complex subunit zeta-1
E 127451240 AP-5 complex subunit zeta-1-like isoform X1 K19025 AP5Z1; AP-5 complex subunit zeta-1
D SMC5-SMC6 complex
E 127433049 structural maintenance of chromosomes protein 5 isoform X1 K22803 SMC5; structural maintenance of chromosomes protein 5
E 127440409 structural maintenance of chromosomes protein 6-like K22804 SMC6; structural maintenance of chromosomes protein 6
E 127454800 structural maintenance of chromosomes protein 6 isoform X1 K22804 SMC6; structural maintenance of chromosomes protein 6
E 127415906 protein LRATD1-like K22805 FAM84A; protein FAM84A
E 127410362 protein LRATD1 K22805 FAM84A; protein FAM84A
E 127451385 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E 127453823 E3 SUMO-protein ligase NSE2 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E 127419669 necdin-like 2 K22823 NSMCE3; non-structural maintenance of chromosomes element 3
E 127411906 non-structural maintenance of chromosomes element 4 homolog A K22825 NSMCE4; non-structural maintenance of chromosomes element 4
E 127432253 SMC5-SMC6 complex localization factor protein 1-like isoform X1 K26126 SLF1; SMC5-SMC6 complex localization factor protein 1
E 127412215 SMC5-SMC6 complex localization factor protein 2-like isoform X1 K26127 SLF2; SMC5-SMC6 complex localization factor protein 2
E 127413685 SMC5-SMC6 complex localization factor protein 2-like isoform X1 K26127 SLF2; SMC5-SMC6 complex localization factor protein 2
D Other HR factors
E 127422824 crossover junction endonuclease EME1 K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E 127455370 exonuclease 3'-5' domain-containing protein 2 isoform X1 K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E 127410951 exonuclease 3'-5' domain-containing protein 2-like K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E 127413506 crossover junction endonuclease MUS81-like isoform X1 K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E 127445049 crossover junction endonuclease MUS81-like isoform X1 K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E 127425064 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 127421356 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 127432976 DNA repair protein SWI5 homolog isoform X1 K10991 SWI5; DNA repair protein Swi5/Sae3
E 127414215 swi5-dependent recombination DNA repair protein 1 homolog K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E 127412495 structure-specific endonuclease subunit SLX1 K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E 127439078 structure-specific endonuclease subunit SLX4-like isoform X1 K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
E 127436429 flap endonuclease GEN homolog 1 isoform X1 K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E 127435557 spatacsin K19026 SPG11; spatacsin
E 127412162 zinc finger FYVE domain-containing protein 26 isoform X1 K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
E 127413973 zinc finger FYVE domain-containing protein 26-like isoform X1 K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
E 127435039 RAD51-associated protein 1-like isoform X1 K20778 RAD51AP1; RAD51-associated protein 1
E 127436409 RAD51-associated protein 1 isoform X1 K20778 RAD51AP1; RAD51-associated protein 1
E 127456005 mortality factor 4-like protein 1 K11339 MORF4L1; mortality factor 4-like protein 1
E 127417244 mortality factor 4-like protein 1 isoform X1 K11339 MORF4L1; mortality factor 4-like protein 1
E 127419204 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 127444657 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 127444666 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 127413838 fidgetin-like protein 1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E 127434538 DNA repair-scaffolding protein K22806 SPIDR; DNA repair-scaffolding protein
E 127424825 protein LRATD2-like K22810 FAM84B; protein FAM84B
E 127420655 protein LRATD2a K22810 FAM84B; protein FAM84B
E 127452449 protein LRATD2-like K22810 FAM84B; protein FAM84B
E 127454068 protein LRATD2 K22810 FAM84B; protein FAM84B
E 127445227 BRCA1-associated ATM activator 1 isoform X1 K23112 BRAT1; BRCA1-associated ATM activator 1
E 127426513 cilia and flagella associated protein 410 K23456 CFAP410; cilla- and flagella-associated protein
E 127438427 hepatoma-derived growth factor-related protein 2-like isoform X1 K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
E 127439286 hepatoma-derived growth factor-related protein 2-like K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
E 127421520 zinc finger SWIM domain-containing protein 7 K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7
E 127450270 ATPase SWSAP1 K25771 SWSAP1; ATPase SWSAP1
E 127433062 BRCA2-interacting transcriptional repressor EMSY-like K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
E 127433808 BRCA2-interacting transcriptional repressor EMSY-like isoform X1 K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
E 127443726 heat shock factor 2-binding protein K25791 HSF2BP; heat shock factor 2-binding protein
E 127453289 protein MMS22-like K26125 MMS22L; protein MMS22-like
E 127453620 protein MMS22-like K26125 MMS22L; protein MMS22-like
E 127454725 tonsoku-like protein isoform X1 K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
E 127411508 tonsoku-like protein K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
E 127418063 biorientation of chromosomes in cell division protein 1-like 1 isoform X1 K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1
E 127435464 PCNA-interacting partner-like K27412 PARPBP; PCNA-interacting partner
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E 127427021 X-ray repair cross-complementing protein 6 isoform X1 K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 127423669 X-ray repair cross-complementing protein 5-like K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 127448244 X-ray repair cross-complementing protein 5 K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
E 127451564 DNA-dependent protein kinase catalytic subunit-like isoform X1 K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D MRX complex
E 127422261 double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 127430403 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E 127443689 DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E 127432605 DNA repair protein XRCC4 isoform X1 K10886 XRCC4; DNA-repair protein XRCC4
E 127433521 DNA repair protein XRCC4-like isoform X1 K10886 XRCC4; DNA-repair protein XRCC4
E 127448835 non-homologous end-joining factor 1-like K10980 NHEJ1; non-homologous end-joining factor 1
D X-family DNA polymerases
E 127443817 DNA polymerase lambda isoform X1 K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 127432587 DNA-directed DNA/RNA polymerase mu K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
E 127433904 DNA-directed DNA/RNA polymerase mu-like isoform X1 K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
E 127412006 DNA nucleotidylexotransferase K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
E 127414375 DNA nucleotidylexotransferase-like K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
E 127424479 DNA polymerase beta-like K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E 127415140 DNA polymerase beta K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E 127443800 aprataxin isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 127443785 aprataxin and PNK-like factor isoform X1 K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 127445026 aprataxin and PNK-like factor isoform X1 K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 127436731 protein artemis-like isoform X1 K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E 127435152 protein artemis-like isoform X1 K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E 127425172 tyrosyl-DNA phosphodiesterase 2-like isoform X1 K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 127421134 tyrosyl-DNA phosphodiesterase 2-like K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 127452935 tyrosyl-DNA phosphodiesterase 2 isoform X1 K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 127450177 structural maintenance of chromosomes flexible hinge domain-containing protein 1-like K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E 127423167 structural maintenance of chromosomes flexible hinge domain-containing protein 1-like isoform X1 K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E 127441279 PWWP domain-containing DNA repair factor 3B-like K23386 PWWP3; PWWP domain-containing DNA repair factor 3
E 127442106 PWWP domain-containing DNA repair factor 3B-like isoform X1 K23386 PWWP3; PWWP domain-containing DNA repair factor 3
E 127419420 protein PAXX-like K25772 PAXX; protein PAXX
E 127439970 protein PAXX-like isoform X1 K25772 PAXX; protein PAXX
E 127437387 si:ch211-127m7.2; uncharacterized protein si:ch211-127m7.2 K26155 CYREN; cell cycle regulator of non-homologous end joining
E 127450266 jmjC domain-containing protein 8 isoform X1 K25792 JMJD8; jumonji domain-containing protein 8
E 127423885 shieldin complex subunit 3-like K26130 SHLD3; shieldin complex subunit 3
C FA (Fanconi anemia) pathway
D FA core complex
E 127435763 Fanconi anemia group A protein isoform X1 K10888 FANCA; fanconi anemia group A protein
E 127414924 Fanconi anemia group C protein isoform X1 K10890 FANCC; fanconi anemia group C protein
E 127424106 Fanconi anemia group E protein-like isoform X1 K10892 FANCE; fanconi anemia group E protein
E 127436307 Fanconi anemia group F protein-like K10893 FANCF; fanconi anemia group F protein
E 127434441 Fanconi anemia group G protein isoform X1 K10894 FANCG; fanconi anemia group G protein
E 127411841 E3 ubiquitin-protein ligase FANCL isoform X1 K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
E 127455159 Fanconi anemia group M protein isoform X1 K10896 FANCM; fanconi anemia group M protein
E 127437474 Fanconi anemia core complex-associated protein 24-like isoform X1 K10898 FAAP24; fanconi anemia-associated protein
E 127435735 Fanconi anemia core complex-associated protein 24-like K10898 FAAP24; fanconi anemia-associated protein
E 127427045 Fanconi anemia core complex-associated protein 100-like isoform X1 K10993 FAAP100; fanconi anemia core complex 100 kDa subunit
D FA core complex binding factors
E 127419009 transcription factor HES-4-B-like K06054 HES1; hairy and enhancer of split 1
E 127419694 transcription factor HES-4-B-like K06054 HES1; hairy and enhancer of split 1
E 127446128 hairy-related 6 K06054 HES1; hairy and enhancer of split 1
E 127441069 transcription factor HES-1-like K06054 HES1; hairy and enhancer of split 1
E 127441976 transcription factor HES-1-like K06054 HES1; hairy and enhancer of split 1
E 127448736 transcription factor HES-1-like K06054 HES1; hairy and enhancer of split 1
E 127449440 centromere protein S-like K11511 APITD1; centromere protein S
E 127445669 centromere protein S-like K11511 APITD1; centromere protein S
E 127450429 centromere protein X K15360 STRA13; centromere protein X
E 127418952 ubiquitin-conjugating enzyme E2 T K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E 127455697 recQ-like DNA helicase BLM K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 127418208 DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 127450139 DNA topoisomerase 3-alpha-like isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 127424669 recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1
E 127452083 recQ-mediated genome instability protein 2 K15365 RMI2; RecQ-mediated genome instability protein 2
D FANCD2-I complex
E 127449519 Fanconi anemia group D2 protein isoform X1 K10891 FANCD2; fanconi anemia group D2 protein
E 127437693 Fanconi anemia group I protein-like K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
E 127422162 LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein homolog K08775 BRCA2; breast cancer 2 susceptibility protein
E 127429461 breast cancer type 2 susceptibility protein isoform X1 K08775 BRCA2; breast cancer 2 susceptibility protein
E 127422042 Fanconi anemia group J protein isoform X1 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E 127443827 partner and localizer of BRCA2 K10897 PALB2; partner and localizer of BRCA2
D Other FA pathway factors
E 127417320 fanconi-associated nuclease 1 K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E 127409705 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 127415683 DNA repair protein RAD51 homolog 1-like K04482 RAD51; DNA repair protein RAD51
E 127432909 DNA repair protein RAD51 homolog 3 isoform X1 K10870 RAD51L2; RAD51-like protein 2
E 127431545 telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
E 127445812 ubiquitin carboxyl-terminal hydrolase 1-like isoform X1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
E 127448866 ubiquitin carboxyl-terminal hydrolase 1-like K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
E 127431913 WD repeat-containing protein 48-like isoform X1 K15361 WDR48; WD repeat-containing protein 48
E 127434617 WD repeat-containing protein 48 isoform X1 K15361 WDR48; WD repeat-containing protein 48
E 127441546 WD repeat-containing protein 48 isoform X1 K15361 WDR48; WD repeat-containing protein 48
E 127443147 WD repeat-containing protein 48-like K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E 127436523 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 127422335 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 127436757 serine/threonine-protein phosphatase 6 regulatory subunit 2-like K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
E 127456437 serine/threonine-protein phosphatase 6 regulatory subunit 2-like isoform X1 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
E 127434900 serine/threonine-protein phosphatase 6 regulatory subunit 2a isoform X1 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
E 127416660 serine/threonine-protein phosphatase 6 regulatory subunit 2-like isoform X1 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
E 127437544 serine/threonine-protein phosphatase 6 regulatory subunit 3-like isoform X1 K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
E 127435896 serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1 K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
E 127425226 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A-like isoform X1 K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
E 127420855 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A-like K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
E 127453049 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1 K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
E 127454183 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
E 127446895 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B-like isoform X1 K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
E 127447841 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B-like isoform X1 K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
E 127418660 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
E 127420445 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C-like K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
E 127428309 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C-like isoform X1 K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
D Ubiquitin ligases
E 127409654 E3 ubiquitin-protein ligase rnf8-like isoform X1 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E 127416320 E3 ubiquitin-protein ligase rnf8-like K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E 127421998 E3 ubiquitin-protein ligase rnf168-like isoform X1 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
E 127430199 E3 ubiquitin-protein ligase rnf168 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
E 127430327 E3 ubiquitin-protein ligase RNF169 isoform X1 K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
E 127421994 E3 ubiquitin-protein ligase RNF169-like isoform X1 K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
E 127446039 E3 ubiquitin-protein ligase HERC2-like isoform X1 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
E 127448869 E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E 127410248 telomerase Cajal body protein 1-like K23314 WRAP53; telomerase Cajal body protein 1
E 127433814 taperin K24164 TPRN; taperin
E 127428668 taperin-like K24164 TPRN; taperin
E 127433073 WD repeat-containing protein 70-like K24752 WDR70; WD repeat-containing protein 70
E 127433816 WD repeat-containing protein 70 isoform X1 K24752 WDR70; WD repeat-containing protein 70
E 127440384 WD repeat-containing protein 76-like isoform X1 K24755 WDR76; WD repeat-containing protein 76
E 127409659 WD repeat-containing protein 76-like K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D 127413925 DNA polymerase eta isoform X1 K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 127432342 DNA polymerase iota K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D 127428632 DNA polymerase kappa K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D 127434591 DNA polymerase kappa-like K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D 127447528 DNA repair protein REV1-like K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
D 127447938 DNA repair protein REV1-like isoform X1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D 127456730 DNA polymerase zeta catalytic subunit K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
D 127415765 DNA polymerase zeta catalytic subunit-like isoform X1 K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
D 127429190 DNA polymerase nu-like K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
C Rad6 epistasis group
D 127412871 ubiquitin-conjugating enzyme E2 A-like isoform X1 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 127447525 ubiquitin-conjugating enzyme E2 A-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 127448205 ubiquitin-conjugating enzyme E2 A-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 127417679 ubiquitin-conjugating enzyme E2 A isoform X1 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 127430698 ubiquitin-conjugating enzyme E2 B K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
D 127429166 ubiquitin-conjugating enzyme E2 B K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
D 127446557 E3 ubiquitin-protein ligase RAD18-like isoform X1 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 127448621 E3 ubiquitin-protein ligase RAD18 isoform X1 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 127442584 helicase-like transcription factor K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 127431501 ubiquitin-conjugating enzyme E2 variant 2-like isoform X1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 127434409 ubiquitin-conjugating enzyme E2 variant 2 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 127428349 ubiquitin-conjugating enzyme E2 variant 1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 127436981 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
D 127456255 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
D 127435223 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
D 127417157 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D 127432231 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 127433437 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
D 127435464 PCNA-interacting partner-like K27412 PARPBP; PCNA-interacting partner
D 127415806 DNA-dependent metalloprotease SPRTN isoform X1 K24051 SPRTN; SprT-like domain-contaning protein Spartan
D 127412954 germ cell nuclear acidic protein isoform X1 K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D 127413237 cell cycle checkpoint control protein RAD9A K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D 127423739 cell cycle checkpoint control protein RAD9B K10995 RAD9B; cell cycle checkpoint control protein RAD9B
D 127431928 checkpoint protein HUS1-like K10903 HUS1; HUS1 checkpoint protein
D 127434178 checkpoint protein HUS1-like K10903 HUS1; HUS1 checkpoint protein
D 127430163 cell cycle checkpoint protein RAD1 isoform X1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D 127426697 cell cycle checkpoint protein RAD17-like K06662 HRAD17; cell cycle checkpoint protein
D 127439986 cell cycle checkpoint protein RAD17-like isoform X1 K06662 HRAD17; cell cycle checkpoint protein
D 127431184 replication factor C subunit 2 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 127426507 replication factor C subunit 4-like K10755 RFC2_4; replication factor C subunit 2/4
D 127428123 replication factor C subunit 4-like isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 127429390 replication factor C subunit 2 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 127430505 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
D 127437916 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
D 127432393 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 127433503 replication factor C subunit 3-like K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D 127430163 cell cycle checkpoint protein RAD1 isoform X1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D 127428232 protein timeless homolog K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D 127453860 TIMELESS-interacting protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D 127425510 claspin-like K25773 CLSPN; claspin
D 127421078 claspin-like isoform X1 K25773 CLSPN; claspin
C Triple T complex
D 127431545 telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
D 127419627 TELO2-interacting protein 1 homolog K20403 TTI1; TELO2-interacting protein 1
D 127424543 TELO2-interacting protein 2 K23115 TTI2; TELO2-interacting protein 2
C BAG6-UBL4A-GET4 complex
D 127425006 large proline-rich protein BAG6 isoform X1 K23390 BAG6; large proline-rich protein BAG6
D 127421036 large proline-rich protein BAG6-like K23390 BAG6; large proline-rich protein BAG6
D 127422073 large proline-rich protein BAG6-like isoform X1 K23390 BAG6; large proline-rich protein BAG6
D 127430168 large proline-rich protein BAG6-like isoform X1 K23390 BAG6; large proline-rich protein BAG6
D 127414842 ubiquitin-like protein 4A K23388 UBL4; ubiquitin-like protein 4
D 127423985 ubiquitin-like protein 4A K23388 UBL4; ubiquitin-like protein 4
D 127427137 Golgi to ER traffic protein 4 homolog K23387 GET4; golgi to ER traffic protein 4
D 127423480 Golgi to ER traffic protein 4 homolog isoform X1 K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D 127440533 serine/threonine-protein kinase ATR isoform X1 K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D 127438552 ATR-interacting protein K10905 ATRIP; ATR interacting protein
D 127439039 ATR-interacting protein-like K10905 ATRIP; ATR interacting protein
D 127429480 serine-protein kinase ATM isoform X1 K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 127412460 cellular tumor antigen p53-like K04451 TP53; tumor protein p53
D 127439189 cellular tumor antigen p53-like isoform X1 K04451 TP53; tumor protein p53
D 127423032 cellular tumor antigen p53-like isoform X1 K04451 TP53; tumor protein p53
D 127429224 serine/threonine-protein kinase Chk1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D 127430321 serine/threonine-protein kinase Chk2-like isoform X1 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 127437788 serine/threonine-protein kinase Chk2-like isoform X1 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 127412277 M-phase inducer phosphatase 1-like K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 127414227 M-phase inducer phosphatase 1-like K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 127424560 14-3-3 protein beta/alpha-B K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127449495 14-3-3 protein beta/alpha-A K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127424858 14-3-3 protein beta/alpha-A-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127455614 14-3-3 protein zeta/delta-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127414655 14-3-3 protein beta/alpha-A-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127420762 14-3-3 protein zeta/delta K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127446440 14-3-3 protein beta/alpha-A-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127452457 14-3-3 protein beta/alpha-A-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127410168 14-3-3 protein beta/alpha-1-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127416498 14-3-3 protein theta K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127454161 14-3-3 protein beta/alpha-A-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127410909 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 127432784 14-3-3 protein gamma-like K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 127433401 14-3-3 protein eta K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 127433424 14-3-3 protein gamma-B-like K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 127422319 14-3-3 protein gamma-B-like K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 127423640 14-3-3 protein gamma-1 K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 127429577 14-3-3 protein gamma-B K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 127430287 14-3-3 protein epsilon isoform X1 K06630 YWHAE; 14-3-3 protein epsilon
D 127421878 14-3-3 protein epsilon-like isoform X1 K06630 YWHAE; 14-3-3 protein epsilon
D 127413258 neuron navigator 2-like K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 127437629 neuron navigator 2-like isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 127444711 neuron navigator 2-like K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 127436089 neuron navigator 2-like K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 127455663 wee1-like protein kinase 2 K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 127456394 wee1-like protein kinase 1-A K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 127416852 wee1-like protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 127433025 period circadian protein homolog 1a isoform X1 K21944 PER1; period circadian protein 1
D 127433183 period circadian protein homolog 1-like K21944 PER1; period circadian protein 1
D 127452111 LOW QUALITY PROTEIN: period circadian protein homolog 1-like K21944 PER1; period circadian protein 1
D 127448190 period circadian protein homolog 1b isoform X1 K21944 PER1; period circadian protein 1
D 127422251 period circadian protein homolog 2-like isoform X1 K02633 PER2; period circadian protein 2
D 127441544 period circadian protein homolog 2-like isoform X1 K02633 PER2; period circadian protein 2
D 127442059 period circadian protein homolog 2-like isoform X1 K02633 PER2; period circadian protein 2
D 127429483 period circadian protein homolog 2-like isoform X1 K02633 PER2; period circadian protein 2
D 127426597 period circadian protein homolog 3-like isoform X1 K21945 PER3; period circadian protein 3
D 127427848 period circadian protein homolog 3-like isoform X1 K21945 PER3; period circadian protein 3
D 127418059 plastin-3 K17336 PLS3; plastin-3
D 127412800 plastin-3-like K17336 PLS3; plastin-3
D 127437724 apoptosis-enhancing nuclease K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]
D 127436172 apoptosis-enhancing nuclease-like K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]
D 127441384 serine/threonine-protein kinase PLK3-like isoform X1 K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
D 127442223 serine/threonine-protein kinase PLK3-like K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
D 127426311 serine/threonine-protein kinase Nek4-like isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 127427800 serine/threonine-protein kinase Nek4-like isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 127410307 serine/threonine-protein kinase Nek1-like isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 127416368 serine/threonine-protein kinase Nek1-like isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 127448242 serine/threonine-protein kinase Nek5 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 127454296 serine/threonine-protein kinase Nek10 K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
D 127454155 serine/threonine-protein kinase Nek11 isoform X1 K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
D 127445342 protein downstream neighbor of son homolog K22422 DONSON; protein downstream neighbor of Son
D 127424444 KN motif and ankyrin repeat domain-containing protein 1-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127424725 KN motif and ankyrin repeat domain-containing protein 3-like isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127449948 KN motif and ankyrin repeat domain-containing protein 2-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127432068 LOW QUALITY PROTEIN: KN motif and ankyrin repeat domain-containing protein 1-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127445811 KN motif and ankyrin repeat domain-containing protein 4-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127452091 KN motif and ankyrin repeat domain-containing protein 2-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127415173 KN motif and ankyrin repeat domain-containing protein 3-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127434799 KN motif and ankyrin repeat domain-containing protein 1-like isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127417414 KN motif and ankyrin repeat domain-containing protein 1b K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127449050 KN motif and ankyrin repeat domain-containing protein 4-like isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 127431787 charged multivesicular body protein 4c-like K24782 CHMP4C; charged multivesicular body protein 4C
D 127434747 charged multivesicular body protein 4c-like K24782 CHMP4C; charged multivesicular body protein 4C
D 127437242 vacuolar protein sorting-associated protein 4A K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 127438487 vacuolar protein sorting-associated protein 4B-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 127438982 vacuolar protein sorting-associated protein 4B-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 127441656 vacuolar protein sorting-associated protein 4B isoform X1 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 127442270 vacuolar protein sorting-associated protein 4B isoform X1 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 127435775 vacuolar protein sorting-associated protein 4A-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 127455220 abscission/NoCut checkpoint regulator-like K24778 ZFYVE19; abscission/NoCut checkpoint regulator
D 127410721 abscission/NoCut checkpoint regulator isoform X1 K24778 ZFYVE19; abscission/NoCut checkpoint regulator
D 127438526 replication stress response regulator SDE2-like K25059 SDE2; replication stress response regulator SDE2
D 127439076 replication stress response regulator SDE2-like K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D 127430728 DNA polymerase theta K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
D 127430123 myb-binding protein 1A-like protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D 127443636 DNA-directed primase/polymerase protein isoform X1 K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Nucleases
D 127427297 DNA cross-link repair 1A protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D 127414452 5' exonuclease Apollo isoform X1 K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
D 127430282 exonuclease V-like K17815 EXO5; exonuclease V [EC:3.1.-.-]
D 127422141 LOW QUALITY PROTEIN: exonuclease V K17815 EXO5; exonuclease V [EC:3.1.-.-]
D 127446055 endonuclease V-like isoform X1 K21813 ENDOV; endonuclease V [EC:3.1.26.-]
D 127437979 DNA annealing helicase and endonuclease ZRANB3 K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D 127421055 ankyrin repeat and LEM domain-containing protein 1 isoform X1 K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
C Helicases
D 127431299 helicase POLQ-like isoform X1 K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
D 127428869 helicase POLQ-like isoform X1 K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
D 127414915 DNA excision repair protein ERCC-6-like 2 K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D 127412848 pre-mRNA-processing factor 19-like K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 127417541 pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 127455173 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 127410696 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 127415058 pre-mRNA-splicing factor SPF27 K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 127423938 pre-mRNA-splicing factor SPF27-like K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 127443751 pleiotropic regulator 1-like K12862 PLRG1; pleiotropic regulator 1
D 127445172 pleiotropic regulator 1 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D 127448942 nucleotide triphosphate diphosphatase NUDT15-like isoform X1 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D 127450205 oxidized purine nucleoside triphosphate hydrolase K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D 127424546 8-oxo-dGDP phosphatase NUDT18 isoform X1 K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D 127455801 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 127417213 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 127431150 ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 127428994 ribonucleoside-diphosphate reductase large subunit-like K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 127425130 ribonucleoside-diphosphate reductase subunit M2 B-like K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D 127420971 ribonucleoside-diphosphate reductase subunit M2 B K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D 127410141 ribonucleoside-diphosphate reductase subunit M2-like isoform X1 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D 127416494 ribonucleoside-diphosphate reductase subunit M2 isoform X1 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 127455269 methylated-DNA--protein-cysteine methyltransferase isoform X1 K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 127442672 CPD photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 127426306 uracil-DNA glycosylase-like isoform X1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127439622 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127422364 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127436077 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 127425976 single-strand-selective monofunctional uracil-DNA glycosylase 1 K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 127452115 DNA-3-methyladenine glycosylase-like K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 127424420 adenine DNA glycosylase-like K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 127414797 adenine DNA glycosylase isoform X1 K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 127443964 endonuclease III-like protein 1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E 127436687 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
E 127434831 single-stranded DNA-binding protein, mitochondrial-like isoform X1 K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D 127436687 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
D 127434831 single-stranded DNA-binding protein, mitochondrial-like isoform X1 K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D 127448942 nucleotide triphosphate diphosphatase NUDT15-like isoform X1 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D 127455801 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 127417213 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024