+C Lipid biosynthesis protein KO
#
Lipid Biosynthesis Proteins - Mycobacterium avium 104
%
!
AFatty acid synthase
B Animal type
B Yeast type
B Bacteria type
C MAV_1650 fatty acid synthase K11533 fas; fatty acid synthase, bacteria type [EC:2.3.1.-]
B Component type
C MAV_2194 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
C MAV_4511 FabD2 protein K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
C MAV_4422 3-oxoacyl-ACP synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
C MAV_4175 oxidoreductase, short chain dehydrogenase/reductase family protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_1572 3-oxoacyl-[acyl-carrier-protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_5088 3-oxoacyl-[acyl-carrier-protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_1809 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_0602 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_4916 oxidoreductase, short chain dehydrogenase/reductase family protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_3101 oxidoreductase, short chain dehydrogenase/reductase family protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_2549 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_3027 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_2962 oxidoreductase, short chain dehydrogenase/reductase family protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_2709 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_2438 oxidoreductase, short chain dehydrogenase/reductase family protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_0894 oxidoreductase, short chain dehydrogenase/reductase family protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_1587 oxidoreductase, short chain dehydrogenase/reductase family protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_5255 NAD dependent epimerase/dehydratase family protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MAV_2769 oxidoreductase, 2-nitropropane dioxygenase family protein K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
C MAV_3169 Acyl-CoA thioesterase K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C MAV_3483 tesB; acyl-CoA thioesterase II K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C MAV_2695 acyl-CoA thioesterase family protein K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C MAV_2540 acyl-CoA thioesterase K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C MAV_5130 conserved hypothetical protein K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C MAV_4612 3-oxoacyl-[acyl-carrier-protein] synthase 3 K11608 mtfabH; mycobacterial beta-ketoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.301]
C MAV_4343 3-oxoacyl-[acyl-carrier-protein] synthase 2 K11609 kasA; meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I [EC:2.3.1.293]
C MAV_2192 3-oxoacyl-[acyl-carrier-protein] synthase 1 K11609 kasA; meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I [EC:2.3.1.293]
C MAV_2191 3-oxoacyl-[acyl-carrier-protein] synthase 2 K27070 kasB; meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II [EC:2.3.1.294]
C MAV_3295 fabG; 3-oxoacyl-(acyl-carrier-protein) reductase K11610 mabA; beta-ketoacyl ACP reductase [EC:1.1.1.100]
C MAV_4527 conserved hypothetical protein K27071 hadA; meromycolic acid (3R)-3-hydroxyacyl-[acyl carrier protein] dehydratase HadA [EC:4.2.1.-]
C MAV_4526 MaoC family protein K27072 hadB; meromycolic acid (3R)-3-hydroxyacyl-[acyl carrier protein] dehydratase HadB [EC:4.2.1.-]
C MAV_4525 conserved hypothetical protein K27073 hadC; meromycolic acid (3R)-3-hydroxyacyl-[acyl carrier protein] dehydratase HadC [EC:4.2.1.-]
C MAV_4646 conserved hypothetical protein K27074 hadD; meromycolic acid (3R)-3-hydroxyacyl-[acyl carrier protein] dehydratase HadD [EC:4.2.1.-]
C MAV_3294 [NADH] enoyl-[acyl-carrier-protein] reductase K11611 inhA; meromycolic acid enoyl-[acyl-carrier-protein] reductase [EC:1.3.1.118]
#
ADesaturase
B First
C MAV_0772 Fatty acid desaturase K03921 FAB2; acyl-[acyl-carrier-protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]
C MAV_1793 Fatty acid desaturase K03921 FAB2; acyl-[acyl-carrier-protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]
C MAV_1216 Fatty acid desaturase K03922 desA2; acyl-[acyl-carrier-protein] desaturase [EC:1.14.19.2]
C MAV_5167 Fatty acid desaturase K22769 desA3; NADPH-dependent stearoyl-CoA 9-desaturase [EC:1.14.19.-]
C MAV_4192 Fatty acid desaturase K22769 desA3; NADPH-dependent stearoyl-CoA 9-desaturase [EC:1.14.19.-]
B Omega
B Front-end
B Sphingolipid
B Other
#
AElongase
B LCFA
B PUFA
B Unclassified
#
APolyketide synthase
B Modular PKS
C MAV_2450 erythronolide synthase, modules 3 and 4 K12436 pks12; mycoketide-CoA synthase [EC:2.3.1.295]
C MAV_0218 polyketide synthase K12437 pks13; polyketide synthase 13
B Component type
C MAV_2011 erythronolide synthase, modules 1 and 2 K04790 mbtC; mycobactin polyketide synthetase MbtC
C MAV_2012 MbtD protein K04791 mbtD; mycobactin polyketide synthetase MbtD
#
AAcyl-CoA synthetase
B Short/medium chain acyl-CoA synthetase
C MAV_0462 acsA; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C MAV_2995 adenylate-forming enzyme K12507 fadK; acyl-CoA synthetase [EC:6.2.1.-]
B Long/very long chain acyl-CoA synthetase
C MAV_2307 putative acyl-CoA dehydrogenase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C MAV_1880 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C MAV_2596 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C MAV_0863 AMP-binding enzyme, putative K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C MAV_4950 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C MAV_3089 acyl-CoA synthase K03822 K03822; putative long chain acyl-CoA synthase [EC:6.2.1.-]
C MAV_1343 acyl-CoA synthase K12429 fadD36; fatty acid CoA ligase FadD36
B Unknown
C MAV_3471 putative acyl-CoA dehydrogenase K12421 fadD9; fatty acid CoA ligase FadD9
C MAV_1328 acyl-CoA synthase K12423 fadD21; fatty acid CoA ligase FadD21
C MAV_1759 acyl-CoA synthase K12423 fadD21; fatty acid CoA ligase FadD21
C MAV_0217 acyl-CoA synthase K12428 fadD32; fatty acid CoA ligase FadD32
C MAV_5018 acyl-CoA synthase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MAV_1150 acyl-CoA synthase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MAV_5076 acyl-CoA ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MAV_4592 acyl-CoA synthase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MAV_5257 acyl-CoA synthase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MAV_0650 acyl-CoA synthase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MAV_1351 acyl-CoA synthase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MAV_3000 acyl-CoA synthase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MAV_5077 long chain fatty acid-CoA ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MAV_2777 acyl-CoA synthase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
#
APhospholipid acyltransferase
B GPAT
C MAV_3220 glycerol-3-phosphate acyltransferase K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
B LPAAT/LPLAT
C MAV_2313 1-acylglycerol-3-phosphate O-acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
#
AOthers
B Multifunctional type
C MAV_1321 mycocerosic acid synthase K12432 pks3_4; mycolipanoate synthase [EC:2.3.1.252]
C MAV_2370 mycocerosic acid synthase K12433 pks5; polyketide synthase 5
C MAV_3109 RifB protein K12434 pks7; polyketide synthase 7
B Component type
!
#
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: November 27, 2023
#
Desaturase/elongase family classification based on Hashimoto et al. (2008)