+F Repair protein KO
#
DNA Repair and Recombination Proteins - Mycolicibacterium boenickei
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MBOE_16960 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MBOE_30470 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MBOE_49970 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E MBOE_51450 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MBOE_39390 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E MBOE_05430 mutY; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MBOE_06340 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E MBOE_22300 helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D MBOE_19330 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MBOE_28080 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MBOE_34830 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MBOE_48110 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MBOE_16960 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MBOE_30470 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MBOE_49970 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E MBOE_51450 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MBOE_14640 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E MBOE_29240 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E MBOE_30480 DNA-3-methyladenine glycosylase K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E MBOE_39390 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E MBOE_05430 mutY; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MBOE_28680 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E MBOE_24090 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MBOE_51220 fpg; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MBOE_33350 formamidopyrimidine-DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E MBOE_56740 endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E MBOE_06340 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E MBOE_03490 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E MBOE_57480 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E MBOE_62660 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
D DNA ligase
E MBOE_51840 ligA; DNA ligase A K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E MBOE_38770 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E MBOE_38920 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E MBOE_38850 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E MBOE_45610 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E MBOE_00550 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MBOE_24160 pcrA; DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MBOE_55010 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MBOE_55160 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MBOE_38770 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E MBOE_51840 ligA; DNA ligase A K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F MBOE_62690 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F MBOE_62680 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F MBOE_61120 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F MBOE_45900 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F MBOE_25480 mfd; transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E MBOE_27340 xseA; exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E MBOE_27330 xseB; exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E MBOE_44610 dnaE1; DNA-directed DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E MBOE_12280 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E MBOE_34120 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E MBOE_06110 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E MBOE_07710 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MBOE_36730 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MBOE_07820 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E MBOE_51840 ligA; DNA ligase A K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E MBOE_00550 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MBOE_24160 pcrA; DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MBOE_55010 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MBOE_55160 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MBOE_11810 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E MBOE_33140 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E MBOE_00020 hypothetical protein K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E MBOE_63090 recC; RecBCD enzyme subunit RecC K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E MBOE_63130 recD; RecBCD enzyme subunit RecD K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E MBOE_48700 recA; protein RecA K03553 recA; recombination protein RecA
E MBOE_47040 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MBOE_47030 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MBOE_47050 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E MBOE_45770 priA_2; putative primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E MBOE_48700 recA; protein RecA K03553 recA; recombination protein RecA
E MBOE_05370 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E MBOE_12300 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E MBOE_51410 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E MBOE_34800 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E MBOE_07760 recR; recombination protein RecR K06187 recR; recombination protein RecR
E MBOE_39460 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E MBOE_47040 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MBOE_47030 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MBOE_47050 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E MBOE_32490 ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E MBOE_23840 ku; non-homologous end joining protein Ku K10979 ku; DNA end-binding protein Ku
E MBOE_23910 ligD_2; multifunctional non-homologous end joining protein LigD K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F MBOE_11640 topoM; topoisomerase subunit TopoM K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F MBOE_12340 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F MBOE_00830 gyrB_1; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F MBOE_11630 topoN; topoisomerase subunit TopoN K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F MBOE_12320 gyrB_2; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F MBOE_06130 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F MBOE_56500 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F MBOE_51550 hypothetical protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F MBOE_34800 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F MBOE_07760 recR; recombination protein RecR K06187 recR; recombination protein RecR
F MBOE_51840 ligA; DNA ligase A K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F MBOE_04160 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MBOE_38920 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F MBOE_38850 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D MBOE_09680 dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D MBOE_44710 dinB1; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D MBOE_52550 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D MBOE_48700 recA; protein RecA K03553 recA; recombination protein RecA
D MBOE_48530 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D MBOE_39460 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D MBOE_59740 DNA polymerase K14161 imuB; protein ImuB
D MBOE_57740 dnaE2; error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D MBOE_11810 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MBOE_33140 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MBOE_48690 recX; regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D MBOE_30630 helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D MBOE_56720 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D MBOE_19330 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MBOE_28080 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MBOE_34830 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MBOE_51540 NUDIX hydrolase K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D MBOE_39530 ADP-ribose pyrophosphatase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D MBOE_48110 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MBOE_52500 nrdE2; ribonucleoside-diphosphate reductase subunit alpha 2 K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MBOE_15310 nrdB; R2-like ligand binding oxidase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D MBOE_52390 nrdF2; ribonucleoside-diphosphate reductase subunit beta nrdF2 K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D MBOE_49460 phosphoesterase K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024