+F Repair protein KO
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DNA Repair and Recombination Proteins - Mycobacterium branderi
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MBRA_31020 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MBRA_48970 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E MBRA_48270 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MBRA_40650 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E MBRA_19710 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MBRA_18690 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E MBRA_24310 helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D MBRA_55340 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MBRA_10640 mutT3; 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MBRA_28210 mutT2; putative 8-oxo-dGTP diphosphatase 2 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MBRA_41530 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MBRA_45150 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MBRA_31020 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MBRA_48970 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E MBRA_48270 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MBRA_30440 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E MBRA_44590 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E MBRA_31030 alkA; putative bifunctional transcriptional activator/DNA repair enzyme AlkA K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E MBRA_40650 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E MBRA_19710 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MBRA_29980 tagA; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E MBRA_41080 mutM_1; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MBRA_48090 mutM_2; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MBRA_25420 putative formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MBRA_33420 nei1; endonuclease 8 1 K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E MBRA_04150 nei2; endonuclease 8 2 K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E MBRA_18690 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E MBRA_10230 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E MBRA_06710 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
D DNA ligase
E MBRA_48780 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E MBRA_41140 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E MBRA_40950 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E MBRA_41030 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E MBRA_42940 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E MBRA_02720 uvrD2; ATP-dependent DNA helicase UvrD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MBRA_02770 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MBRA_25480 uvrD1; ATP-dependent DNA helicase UvrD1 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MBRA_41140 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E MBRA_48780 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F MBRA_06730 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F MBRA_06720 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F MBRA_05590 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F MBRA_43200 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F MBRA_26480 mfd; transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E MBRA_27480 xseA; exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E MBRA_27470 xseB; exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E MBRA_41820 dnaE1; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E MBRA_16200 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E MBRA_34070 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E MBRA_18970 DNA polymerase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E MBRA_36310 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MBRA_18180 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MBRA_18080 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E MBRA_48780 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E MBRA_02720 uvrD2; ATP-dependent DNA helicase UvrD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MBRA_02770 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MBRA_25480 uvrD1; ATP-dependent DNA helicase UvrD1 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MBRA_33280 hypothetical protein K03111 ssb; single-strand DNA-binding protein
E MBRA_15780 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E MBRA_07130 recB; RecBCD enzyme subunit RecB K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E MBRA_07120 recC; RecBCD enzyme subunit RecC K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E MBRA_07140 recD; RecBCD enzyme subunit RecD K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E MBRA_45590 recA; protein RecA K03553 recA; recombination protein RecA
E MBRA_44100 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MBRA_44090 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MBRA_44110 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E MBRA_43100 priA_2; putative primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E MBRA_45590 recA; protein RecA K03553 recA; recombination protein RecA
E MBRA_19800 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E MBRA_16210 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E MBRA_48240 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E MBRA_34700 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E MBRA_18140 recR; recombination protein RecR K06187 recR; recombination protein RecR
E MBRA_40570 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E MBRA_44100 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MBRA_44090 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MBRA_44110 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E MBRA_33080 ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E MBRA_25190 ku; non-homologous end joining protein Ku K10979 ku; DNA end-binding protein Ku
E MBRA_41070 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E MBRA_25230 ligD; multifunctional non-homologous end joining protein LigD K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F MBRA_16240 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F MBRA_16230 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F MBRA_40220 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F MBRA_18950 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F MBRA_48360 hypothetical protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F MBRA_34700 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F MBRA_18140 recR; recombination protein RecR K06187 recR; recombination protein RecR
F MBRA_48780 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F MBRA_40950 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F MBRA_41030 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D MBRA_41890 dinB1; DNA polymerase IV 1 K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D MBRA_49210 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D MBRA_16520 dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D MBRA_45590 recA; protein RecA K03553 recA; recombination protein RecA
D MBRA_45400 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D MBRA_40570 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D MBRA_04910 hypothetical protein K14161 imuB; protein ImuB
D MBRA_04800 dnaE2; error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D MBRA_33280 hypothetical protein K03111 ssb; single-strand DNA-binding protein
D MBRA_15780 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MBRA_00260 hypothetical protein K14623 dinD; DNA-damage-inducible protein D
D MBRA_00990 hypothetical protein K14623 dinD; DNA-damage-inducible protein D
D MBRA_45580 recX; regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D MBRA_31120 dinG; putative ATP-dependent helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D MBRA_04140 lhr; ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D MBRA_55340 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MBRA_10640 mutT3; 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MBRA_28210 mutT2; putative 8-oxo-dGTP diphosphatase 2 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MBRA_41530 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MBRA_48350 mutT1; 8-oxo-dGTP diphosphatase K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D MBRA_40530 NUDIX hydrolase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D MBRA_45150 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MBRA_49160 nrdE; ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MBRA_29560 nrdZ; vitamin B12-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MBRA_49130 nrdF2; ribonucleoside-diphosphate reductase subunit beta nrdF2 K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D MBRA_12760 R2-like ligand binding oxidase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D MBRA_46410 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024