+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Micromonospora carbonacea

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS D Chivosazol hybrid PKS-NRPS E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS D Difficidin PKS D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) D HXZ27_04065 evdD3; acyltransferase domain-containing protein K15320 ATX; 6-methylsalicylic acid synthase [EC:2.3.1.165] D HXZ27_20980 acyltransferase domain-containing protein K15320 ATX; 6-methylsalicylic acid synthase [EC:2.3.1.165] C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:AN1034.2] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:AN1036.2] C Bacterial type D HXZ27_19185 SDR family NAD(P)-dependent oxidoreductase K15314 sgcE; enediyne polyketide synthase B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS E HXZ27_15990 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K14667 whiEIII; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-] E HXZ27_15995 ketosynthase chain-length factor K14668 whiEIV; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-] E HXZ27_18160 ketosynthase chain-length factor K14668 whiEIV; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-] E HXZ27_16000 acyl carrier protein K14669 whiEV; minimal PKS acyl carrier protein E HXZ27_16005 SRPBCC family protein K14670 whiEVI; aromatase E HXZ27_18145 SRPBCC family protein K14670 whiEVI; aromatase E HXZ27_18130 TcmI family type II polyketide cyclase K14671 whiEVII; cyclase E HXZ27_18140 TcmI family type II polyketide cyclase K14671 whiEVII; cyclase C C7-C14 cyclized polyketide type D Octaketide PKS D Nonaketide PKS D Decaketide PKS B Type III PKS C Plant type C Fungal type C Bacterial type D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) D HXZ27_24215 amino acid adenylation domain-containing protein K15395 ftdB; hybrid polyketide synthase / nonribosomal peptide synthetase FtdB # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:AN2545.2] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D HXZ27_06735 MbtH family protein K05375 mbtH; MbtH protein D HXZ27_17030 MbtH family protein K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase C Bacillibactin synthetase C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase C Mycobactin synthetase C Vibriobactin synthetase C Myxochelin synthetase C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase # APolyketide tailoring proteins B Hydrolase C HXZ27_19180 acyl-CoA thioesterase K15315 sgcE10; enediyne core biosynthesis thioesterase B Ketoreductase B Oxygenase C HXZ27_10340 bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase K16022 rif19; flavoprotein hydroxylase C HXZ27_15985 cupin domain-containing protein K14673 whiEII; putative monooxygenase C HXZ27_18150 cupin domain-containing protein K14673 whiEII; putative monooxygenase B Methylase B Glycosyltransferase B Halogenase B beta-Branched incorporating proteins B Others C HXZ27_31165 3-hydroxyacyl-CoA dehydrogenase family protein K16024 asm13; methoxymalonate biosynthesis protein C HXZ27_31160 acyl carrier protein K16025 asm14; methoxymalonate biosynthesis acyl carrier protein C HXZ27_31155 acyl-CoA dehydrogenase family protein K16026 asm15; methoxymalonate biosynthesis protein C HXZ27_31145 HAD-IIIC family phosphatase K16027 asm16; methoxymalonate biosynthesis protein C HXZ27_19165 DUF1702 family protein K21161 sgcE3; enediyne biosynthesis protein E3 C HXZ27_19195 CRTAC1 family protein K21162 sgcE4; enediyne biosynthesis protein E4 C HXZ27_19190 enediyne biosynthesis protein K21163 sgcE5; enediyne biosynthesis protein E5 C HXZ27_19170 cytochrome P450 K21164 sgcE7; enediyne biosynthesis protein E7 C HXZ27_19175 flavin reductase family protein K21185 sgcE6; flavin reductase # ANonribosomal peptide tailoring proteins B Reductase B Thioesterase B Oxygenase B Glycosyltransferase C HXZ27_03580 glycosyltransferase family 1 protein K16444 gtfB; vancomycin aglycone glucosyltransferase [EC:2.4.1.310] C HXZ27_05415 glycosyltransferase family 1 protein K16444 gtfB; vancomycin aglycone glucosyltransferase [EC:2.4.1.310] B Aminotransferase C HXZ27_18280 PLP-dependent aminotransferase family protein K16423 hpgT; (S)-3,5-dihydroxyphenylglycine transaminase [EC:2.6.1.103] B Others C HXZ27_08180 aminotransferase class V-fold PLP-dependent enzyme K04127 cefD; isopenicillin-N epimerase [EC:5.1.1.17] C HXZ27_18210 hppD; 4-hydroxyphenylpyruvate dioxygenase K16421 hmaS; 4-hydroxymandelate synthase [EC:1.13.11.46] C HXZ27_13965 alpha-hydroxy-acid oxidizing protein K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46] C HXZ27_18275 alpha-hydroxy-acid oxidizing protein K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: February 19, 2024