+D GENES KO
#
KEGG Orthology (KO) - Methylacidiphilum caldifontis
%
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:mcao00010]
D IT6_04800 glk; glucokinase K00845 glk; glucokinase [EC:2.7.1.2]
D IT6_01595 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D IT6_05175 ATP-dependent 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
D IT6_00185 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D IT6_08965 class 1 fructose-bisphosphatase K01086 fbp-SEBP; fructose-1,6-bisphosphatase I / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37]
D IT6_07600 ketose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D IT6_05205 aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D IT6_01525 triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D IT6_01515 gap; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D IT6_01520 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D IT6_03720 gpmA; 2,3-diphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D IT6_07705 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D IT6_06065 hypothetical protein K00873 PK; pyruvate kinase [EC:2.7.1.40]
D IT6_06810 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D IT6_06535 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D IT6_09415 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D IT6_01640 pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D IT6_01645 alpha-ketoacid dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D IT6_01655 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D IT6_06755 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_00830 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01660 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_06035 nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D IT6_07540 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D IT6_08300 zinc-dependent alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D IT6_07130 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D IT6_05195 phospho-sugar mutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D IT6_02155 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
C 00020 Citrate cycle (TCA cycle) [PATH:mcao00020]
D IT6_01545 acnA; aconitate hydratase AcnA K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D IT6_01920 NADP-dependent isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D IT6_06745 2-oxoglutarate dehydrogenase E1 component K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
D IT6_06750 odhB; 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D IT6_06755 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_00830 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01660 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01455 sucD; succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D IT6_01460 sucC; ADP-forming succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D IT6_07970 fumarate reductase/succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D IT6_07975 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D IT6_07965 succinate dehydrogenase cytochrome b subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D IT6_02425 fumC; class II fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D IT6_00130 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D IT6_02155 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D IT6_01640 pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D IT6_01645 alpha-ketoacid dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D IT6_01655 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D IT6_06035 nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
C 00030 Pentose phosphate pathway [PATH:mcao00030]
D IT6_01595 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D IT6_07520 zwf; glucose-6-phosphate dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D IT6_09975 zwf; glucose-6-phosphate dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D IT6_09980 pgl; 6-phosphogluconolactonase K01057 PGLS; 6-phosphogluconolactonase [EC:3.1.1.31]
D IT6_07235 gndA; NADP-dependent phosphogluconate dehydrogenase K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D IT6_08350 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D IT6_03690 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D IT6_00545 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D IT6_01165 tal; transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D IT6_07230 rpiB; ribose 5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D IT6_02085 phosphoketolase family protein K01621 xfp; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22]
D IT6_08310 deoC; deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]
D IT6_01315 ribokinase K00852 rbsK; ribokinase [EC:2.7.1.15]
D IT6_05195 phospho-sugar mutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D IT6_03395 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D IT6_07600 ketose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D IT6_05205 aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D IT6_00185 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D IT6_08965 class 1 fructose-bisphosphatase K01086 fbp-SEBP; fructose-1,6-bisphosphatase I / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37]
D IT6_05175 ATP-dependent 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
C 00040 Pentose and glucuronate interconversions [PATH:mcao00040]
D IT6_06490 UDP-glucose/GDP-mannose dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D IT6_08350 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D IT6_03690 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
C 00051 Fructose and mannose metabolism [PATH:mcao00051]
D IT6_08445 class I mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D IT6_08490 mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D IT6_05605 NAD-dependent epimerase/dehydratase family protein K02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271]
D IT6_05175 ATP-dependent 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
D IT6_00185 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D IT6_08965 class 1 fructose-bisphosphatase K01086 fbp-SEBP; fructose-1,6-bisphosphatase I / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37]
D IT6_07600 ketose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D IT6_05205 aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D IT6_01525 triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D IT6_07230 rpiB; ribose 5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D IT6_04955 PTS sugar transporter subunit IIA K02768 fruB; fructose PTS system EIIA component [EC:2.7.1.202]
C 00052 Galactose metabolism [PATH:mcao00052]
D IT6_04470 DUF4931 domain-containing protein K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
D IT6_08225 galE; UDP-glucose 4-epimerase GalE K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D IT6_05195 phospho-sugar mutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D IT6_04800 glk; glucokinase K00845 glk; glucokinase [EC:2.7.1.2]
D IT6_05175 ATP-dependent 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
C 00053 Ascorbate and aldarate metabolism [PATH:mcao00053]
D IT6_06490 UDP-glucose/GDP-mannose dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D IT6_04060 GDP-mannose 4,6-dehydratase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
C 00500 Starch and sucrose metabolism [PATH:mcao00500]
D IT6_07140 bglX; beta-glucosidase BglX K05349 bglX; beta-glucosidase [EC:3.2.1.21]
D IT6_03975 glucose-1-phosphate cytidylyltransferase K00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33]
D IT6_07165 glucose-1-phosphate adenylyltransferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]
D IT6_05935 glgA; glycogen synthase GlgA K00703 glgA; starch synthase [EC:2.4.1.21]
D IT6_01560 glgB; 1,4-alpha-glucan branching protein GlgB K00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]
D IT6_09640 DUF1957 domain-containing protein K16149 K16149; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]
D IT6_07495 glgP; alpha-glucan family phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
D IT6_02435 glgP; alpha-glucan family phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
D IT6_03435 glycogen/starch/alpha-glucan phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
D IT6_01580 treS; maltose alpha-D-glucosyltransferase K05343 treS; maltose alpha-D-glucosyltransferase / alpha-amylase [EC:5.4.99.16 3.2.1.1]
D IT6_01900 4-alpha-glucanotransferase K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25]
D IT6_00265 glycoside hydrolase family 57 K22451 jgt; 4-alpha-glucanotransferase [EC:2.4.1.25]
D IT6_04480 DUF1926 domain-containing protein K22451 jgt; 4-alpha-glucanotransferase [EC:2.4.1.25]
D IT6_04750 alpha-1,4-glucan--maltose-1-phosphate maltosyltransferase K16147 glgE; starch synthase (maltosyl-transferring) [EC:2.4.99.16]
D IT6_00270 glycosidase K16147 glgE; starch synthase (maltosyl-transferring) [EC:2.4.99.16]
D IT6_03815 glgX; glycogen debranching protein GlgX K01214 ISA; isoamylase [EC:3.2.1.68]
D IT6_01590 treY; malto-oligosyltrehalose synthase K06044 treY; (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase [EC:5.4.99.15]
D IT6_01585 treZ; malto-oligosyltrehalose trehalohydrolase K01236 treZ; maltooligosyltrehalose trehalohydrolase [EC:3.2.1.141]
D IT6_05195 phospho-sugar mutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D IT6_04800 glk; glucokinase K00845 glk; glucokinase [EC:2.7.1.2]
D IT6_01595 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:mcao00520]
D IT6_08725 glycoside hydrolase family 3 protein K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]
D IT6_02990 amidohydrolase family protein K01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]
D IT6_07170 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D IT6_04325 glmM; phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D IT6_10290 UDP-N-acetylglucosamine diphosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
D IT6_01180 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D IT6_08925 N-acetylmuramic acid 6-phosphate etherase K07106 murQ; N-acetylmuramic acid 6-phosphate etherase [EC:4.2.1.126]
D IT6_08130 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D IT6_04800 glk; glucokinase K00845 glk; glucokinase [EC:2.7.1.2]
D IT6_05195 phospho-sugar mutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D IT6_06490 UDP-glucose/GDP-mannose dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D IT6_04470 DUF4931 domain-containing protein K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
D IT6_08225 galE; UDP-glucose 4-epimerase GalE K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D IT6_04060 GDP-mannose 4,6-dehydratase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
D IT6_01595 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D IT6_08445 class I mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D IT6_08490 mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D IT6_04110 DegT/DnrJ/EryC1/StrS aminotransferase family protein K13010 per; perosamine synthetase [EC:2.6.1.102]
D IT6_05605 NAD-dependent epimerase/dehydratase family protein K02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271]
D IT6_03975 glucose-1-phosphate cytidylyltransferase K00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33]
D IT6_07165 glucose-1-phosphate adenylyltransferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]
C 00620 Pyruvate metabolism [PATH:mcao00620]
D IT6_07130 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D IT6_06035 nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D IT6_01640 pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D IT6_01645 alpha-ketoacid dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D IT6_01655 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D IT6_06755 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_00830 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01660 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_07540 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D IT6_08300 zinc-dependent alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D IT6_07660 acetate/propionate family kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D IT6_06065 hypothetical protein K00873 PK; pyruvate kinase [EC:2.7.1.40]
D IT6_06810 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D IT6_09110 acetyl-CoA carboxylase carboxyltransferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D IT6_09165 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D IT6_07890 accC; acetyl-CoA carboxylase biotin carboxylase subunit K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D IT6_09095 acetyl-CoA carboxylase carboxyltransferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D IT6_08730 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D IT6_08355 VOC family protein K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
D IT6_09390 VOC family protein K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
D IT6_09210 MBL fold metallo-hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D IT6_01870 MBL fold metallo-hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D IT6_00130 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D IT6_02425 fumC; class II fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D IT6_08755 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D IT6_02155 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D IT6_06535 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D IT6_09415 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D IT6_02135 aceB; malate synthase A K01638 aceB; malate synthase [EC:2.3.3.9]
D IT6_04700 citramalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D IT6_08745 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D IT6_04235 homocitrate synthase K02594 nifV; homocitrate synthase NifV [EC:2.3.3.14]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:mcao00630]
D IT6_02140 aceA; isocitrate lyase K01637 E4.1.3.1; isocitrate lyase [EC:4.1.3.1]
D IT6_07130 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D IT6_02135 aceB; malate synthase A K01638 aceB; malate synthase [EC:2.3.3.9]
D IT6_00130 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D IT6_01545 acnA; aconitate hydratase AcnA K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D IT6_08400 FAD-binding protein K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14]
D IT6_09375 FAD-binding protein K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14]
D IT6_02125 FAD-binding protein K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14]
D IT6_02120 glcE; glycolate oxidase subunit GlcE K11472 glcE; glycolate dehydrogenase FAD-binding subunit [EC:1.1.99.14]
D IT6_09370 (Fe-S)-binding protein K11473 glcF; glycolate dehydrogenase iron-sulfur subunit [EC:1.1.99.14]
D IT6_02115 glcF; glycolate oxidase subunit GlcF K11473 glcF; glycolate dehydrogenase iron-sulfur subunit [EC:1.1.99.14]
D IT6_00525 form I ribulose bisphosphate carboxylase large subunit K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D IT6_00530 ribulose bisphosphate carboxylase small subunit K01602 rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39]
D IT6_00255 alanine--glyoxylate aminotransferase family protein K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D IT6_05785 gltB; glutamate synthase large subunit K00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]
D IT6_00820 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D IT6_09090 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D IT6_05350 gcvP; aminomethyl-transferring glycine dehydrogenase K00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]
D IT6_05340 gcvT; glycine cleavage system aminomethyltransferase GcvT K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D IT6_06755 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_00830 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01660 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_05345 gcvH; glycine cleavage system protein GcvH K02437 gcvH; glycine cleavage system H protein
D IT6_00300 NAD-dependent formate dehydrogenase K00122 FDH; formate dehydrogenase [EC:1.17.1.9]
D IT6_00700 formate dehydrogenase subunit delta K00126 fdsD; formate dehydrogenase subunit delta [EC:1.17.1.9]
D IT6_00695 fdhF; formate dehydrogenase subunit alpha K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9]
D IT6_00690 NADH-quinone oxidoreductase subunit NuoF K00124 fdoH; formate dehydrogenase iron-sulfur subunit
D IT6_00685 NAD(P)H-dependent oxidoreductase subunit E K00127 fdoI; formate dehydrogenase subunit gamma
C 00640 Propanoate metabolism [PATH:mcao00640]
D IT6_07130 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D IT6_07660 acetate/propionate family kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D IT6_06755 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_00830 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01660 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_09110 acetyl-CoA carboxylase carboxyltransferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D IT6_09165 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D IT6_07890 accC; acetyl-CoA carboxylase biotin carboxylase subunit K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D IT6_09095 acetyl-CoA carboxylase carboxyltransferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D IT6_01635 aspartate aminotransferase family protein K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D IT6_01460 sucC; ADP-forming succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D IT6_01455 sucD; succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D IT6_07775 citrate synthase/methylcitrate synthase K01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]
D IT6_03685 bifunctional 2-methylcitrate dehydratase/aconitate hydratase K01720 prpD; 2-methylcitrate dehydratase [EC:4.2.1.79]
C 00650 Butanoate metabolism [PATH:mcao00650]
D IT6_07970 fumarate reductase/succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D IT6_07975 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D IT6_07965 succinate dehydrogenase cytochrome b subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D IT6_06905 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D IT6_01635 aspartate aminotransferase family protein K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D IT6_08795 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D IT6_06035 nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D IT6_05990 ilvB; biosynthetic-type acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D IT6_08735 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
C 00660 C5-Branched dibasic acid metabolism [PATH:mcao00660]
D IT6_05990 ilvB; biosynthetic-type acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D IT6_08735 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D IT6_01460 sucC; ADP-forming succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D IT6_01455 sucD; succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D IT6_02920 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D IT6_09700 3-isopropylmalate dehydratase K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D IT6_09695 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
C 00562 Inositol phosphate metabolism [PATH:mcao00562]
D IT6_05905 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D IT6_01525 triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:mcao00190]
D IT6_05870 NADH-quinone oxidoreductase subunit A K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D IT6_07275 nuoB; NADH-quinone oxidoreductase subunit NuoB K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D IT6_07280 NADH-quinone oxidoreductase subunit C K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
D IT6_07285 nuoD; NADH dehydrogenase (quinone) subunit D K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
D IT6_07290 NAD(P)H-dependent oxidoreductase subunit E K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]
D IT6_07295 nuoF; NADH-quinone oxidoreductase subunit NuoF K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
D IT6_07300 molybdopterin-dependent oxidoreductase K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]
D IT6_07305 NADH-quinone oxidoreductase subunit H K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D IT6_05560 NADH-quinone oxidoreductase subunit I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D IT6_05555 NADH-quinone oxidoreductase subunit J K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D IT6_05550 nuoK; NADH-quinone oxidoreductase subunit NuoK K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D IT6_05545 nuoL; NADH-quinone oxidoreductase subunit L K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D IT6_05540 NADH-quinone oxidoreductase subunit M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
D IT6_05535 NADH-quinone oxidoreductase subunit N K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D IT6_07970 fumarate reductase/succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D IT6_07975 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D IT6_07965 succinate dehydrogenase cytochrome b subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D IT6_10245 cyoE; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D IT6_04525 cytochrome C oxidase subunit IV family protein K02277 coxD; cytochrome c oxidase subunit IV [EC:7.1.1.9]
D IT6_04530 heme-copper oxidase subunit III K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]
D IT6_07530 cbb3-type cytochrome c oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D IT6_00710 cbb3-type cytochrome c oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D IT6_01405 cbb3-type cytochrome c oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D IT6_04535 cbb3-type cytochrome c oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D IT6_00715 cytochrome c oxidase subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D IT6_01410 cytochrome c oxidase subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D IT6_04505 hypothetical protein K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D IT6_10250 COX15/CtaA family protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D IT6_04550 cytochrome oxidase K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9]
D IT6_04545 cbb3-type cytochrome c oxidase subunit II K00405 ccoO; cytochrome c oxidase cbb3-type subunit II
D IT6_04515 hypothetical protein K00407 ccoQ; cytochrome c oxidase cbb3-type subunit IV
D IT6_06205 F0F1 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D IT6_02165 F0F1 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D IT6_06215 atpD; F0F1 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D IT6_02195 F0F1 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D IT6_06210 atpG; ATP synthase F1 subunit gamma K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D IT6_02160 F0F1 ATP synthase subunit gamma K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D IT6_06220 atpC; ATP synthase F1 subunit epsilon K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D IT6_02190 hypothetical protein K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D IT6_06185 atpB; F0F1 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D IT6_02180 F0F1 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D IT6_06195 atpF; F0F1 ATP synthase subunit B K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D IT6_02170 F0F1 ATP synthase subunit delta K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D IT6_06190 ATPase K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D IT6_02175 atpE; ATP synthase F0 subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D IT6_02935 HAD-IC family P-type ATPase K01535 PMA1; H+-transporting ATPase [EC:7.1.2.1]
D IT6_04195 inorganic diphosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
D IT6_10205 ppk1; polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:mcao00710]
D IT6_00525 form I ribulose bisphosphate carboxylase large subunit K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D IT6_00530 ribulose bisphosphate carboxylase small subunit K01602 rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39]
D IT6_01520 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D IT6_01515 gap; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D IT6_07600 ketose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D IT6_00185 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D IT6_08965 class 1 fructose-bisphosphatase K01086 fbp-SEBP; fructose-1,6-bisphosphatase I / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37]
D IT6_00545 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D IT6_07230 rpiB; ribose 5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D IT6_08970 phosphoribulokinase K00855 PRK; phosphoribulokinase [EC:2.7.1.19]
D IT6_00540 phosphoribulokinase K00855 PRK; phosphoribulokinase [EC:2.7.1.19]
D IT6_01525 triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D IT6_08350 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D IT6_03690 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D IT6_01165 tal; transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D IT6_08755 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D IT6_02155 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D IT6_00130 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00720 Other carbon fixation pathways [PATH:mcao00720]
D IT6_06035 nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]
D IT6_06535 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D IT6_09415 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D IT6_08755 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D IT6_00130 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D IT6_02425 fumC; class II fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D IT6_07970 fumarate reductase/succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D IT6_07975 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D IT6_07965 succinate dehydrogenase cytochrome b subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D IT6_01455 sucD; succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D IT6_01460 sucC; ADP-forming succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D IT6_01920 NADP-dependent isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D IT6_01545 acnA; aconitate hydratase AcnA K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D IT6_09110 acetyl-CoA carboxylase carboxyltransferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D IT6_09165 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D IT6_07890 accC; acetyl-CoA carboxylase biotin carboxylase subunit K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D IT6_09095 acetyl-CoA carboxylase carboxyltransferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D IT6_07925 formate--tetrahydrofolate ligase K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
D IT6_02350 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D IT6_07660 acetate/propionate family kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D IT6_07130 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 00680 Methane metabolism [PATH:mcao00680]
D IT6_09400 methane monooxygenase K10944 pmoA-amoA; methane/ammonia monooxygenase subunit A [EC:1.14.18.3 1.14.99.39]
D IT6_09940 methane monooxygenase/ammonia monooxygenase subunit A K10944 pmoA-amoA; methane/ammonia monooxygenase subunit A [EC:1.14.18.3 1.14.99.39]
D IT6_09955 methane monooxygenase/ammonia monooxygenase subunit A K10944 pmoA-amoA; methane/ammonia monooxygenase subunit A [EC:1.14.18.3 1.14.99.39]
D IT6_09405 methane monooxygenase/ammonia monooxygenase subunit B K10945 pmoB-amoB; methane/ammonia monooxygenase subunit B
D IT6_09945 methane monooxygenase/ammonia monooxygenase subunit B K10945 pmoB-amoB; methane/ammonia monooxygenase subunit B
D IT6_09960 methane monooxygenase/ammonia monooxygenase subunit B K10945 pmoB-amoB; methane/ammonia monooxygenase subunit B
D IT6_09395 methane monooxygenase K10946 pmoC-amoC; methane/ammonia monooxygenase subunit C
D IT6_09935 methane monooxygenase/ammonia monooxygenase subunit C K10946 pmoC-amoC; methane/ammonia monooxygenase subunit C
D IT6_09950 methane monooxygenase/ammonia monooxygenase subunit C K10946 pmoC-amoC; methane/ammonia monooxygenase subunit C
D IT6_09965 methane monooxygenase/ammonia monooxygenase subunit C K10946 pmoC-amoC; methane/ammonia monooxygenase subunit C
D IT6_01685 methanol/ethanol family PQQ-dependent dehydrogenase K23995 xoxF; lanthanide-dependent methanol dehydrogenase [EC:1.1.2.10]
D IT6_00300 NAD-dependent formate dehydrogenase K00122 FDH; formate dehydrogenase [EC:1.17.1.9]
D IT6_00695 fdhF; formate dehydrogenase subunit alpha K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9]
D IT6_00690 NADH-quinone oxidoreductase subunit NuoF K00124 fdoH; formate dehydrogenase iron-sulfur subunit
D IT6_00685 NAD(P)H-dependent oxidoreductase subunit E K00127 fdoI; formate dehydrogenase subunit gamma
D IT6_00700 formate dehydrogenase subunit delta K00126 fdsD; formate dehydrogenase subunit delta [EC:1.17.1.9]
D IT6_09090 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D IT6_00255 alanine--glyoxylate aminotransferase family protein K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D IT6_07705 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D IT6_08755 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D IT6_00130 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D IT6_07600 ketose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D IT6_05205 aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D IT6_00185 glpX; class II fructose-bisphosphatase K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D IT6_08965 class 1 fructose-bisphosphatase K01086 fbp-SEBP; fructose-1,6-bisphosphatase I / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37]
D IT6_05175 ATP-dependent 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
D IT6_04785 methylamine dehydrogenase K15228 mauA; methylamine dehydrogenase light chain [EC:1.4.9.1]
D IT6_04770 methylamine dehydrogenase K15229 mauB; methylamine dehydrogenase heavy chain [EC:1.4.9.1]
D IT6_07660 acetate/propionate family kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D IT6_07130 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D IT6_06535 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D IT6_09415 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D IT6_03720 gpmA; 2,3-diphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D IT6_00570 phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
C 00910 Nitrogen metabolism [PATH:mcao00910]
D IT6_01280 NarK/NasA family nitrate transporter K02575 NRT2; MFS transporter, NNP family, nitrate/nitrite transporter
D IT6_01255 ABC transporter substrate-binding protein K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4]
D IT6_01265 molybdopterin oxidoreductase family protein K00372 nasC; assimilatory nitrate reductase catalytic subunit [EC:1.7.99.-]
D IT6_01270 NAD(P)/FAD-dependent oxidoreductase K26139 nasD; nitrite reductase [NAD(P)H] large subunit [EC:1.7.1.4]
D IT6_01275 Rieske (2Fe-2S) protein K26138 nasE; nitrite reductase [NAD(P)H] small subunit [EC:1.7.1.4]
D IT6_01980 multicopper oxidase domain-containing protein K00368 nirK; nitrite reductase (NO-forming) [EC:1.7.2.1]
D IT6_06635 cbb3-type cytochrome c oxidase subunit I K04561 norB; nitric oxide reductase subunit B [EC:1.7.2.5]
D IT6_06630 cytochrome c K02305 norC; nitric oxide reductase subunit C
D IT6_04585 nosZ; Sec-dependent nitrous-oxide reductase K00376 nosZ; nitrous-oxide reductase [EC:1.7.2.4]
D IT6_04225 nifD; nitrogenase molybdenum-iron protein alpha chain K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1]
D IT6_04220 nifK; nitrogenase molybdenum-iron protein subunit beta K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]
D IT6_04230 nifH; nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH
D IT6_09400 methane monooxygenase K10944 pmoA-amoA; methane/ammonia monooxygenase subunit A [EC:1.14.18.3 1.14.99.39]
D IT6_09940 methane monooxygenase/ammonia monooxygenase subunit A K10944 pmoA-amoA; methane/ammonia monooxygenase subunit A [EC:1.14.18.3 1.14.99.39]
D IT6_09955 methane monooxygenase/ammonia monooxygenase subunit A K10944 pmoA-amoA; methane/ammonia monooxygenase subunit A [EC:1.14.18.3 1.14.99.39]
D IT6_09405 methane monooxygenase/ammonia monooxygenase subunit B K10945 pmoB-amoB; methane/ammonia monooxygenase subunit B
D IT6_09945 methane monooxygenase/ammonia monooxygenase subunit B K10945 pmoB-amoB; methane/ammonia monooxygenase subunit B
D IT6_09960 methane monooxygenase/ammonia monooxygenase subunit B K10945 pmoB-amoB; methane/ammonia monooxygenase subunit B
D IT6_09395 methane monooxygenase K10946 pmoC-amoC; methane/ammonia monooxygenase subunit C
D IT6_09935 methane monooxygenase/ammonia monooxygenase subunit C K10946 pmoC-amoC; methane/ammonia monooxygenase subunit C
D IT6_09950 methane monooxygenase/ammonia monooxygenase subunit C K10946 pmoC-amoC; methane/ammonia monooxygenase subunit C
D IT6_09965 methane monooxygenase/ammonia monooxygenase subunit C K10946 pmoC-amoC; methane/ammonia monooxygenase subunit C
D IT6_06280 c-type cytochrome K10535 hao; hydroxylamine dehydrogenase [EC:1.7.2.6]
D IT6_08675 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D IT6_00820 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D IT6_05785 gltB; glutamate synthase large subunit K00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]
D IT6_03590 cynS; cyanase K01725 cynS; cyanate lyase [EC:4.2.1.104]
D IT6_09460 carbonic anhydrase K01673 cynT; carbonic anhydrase [EC:4.2.1.1]
C 00920 Sulfur metabolism [PATH:mcao00920]
D IT6_04250 cysC; adenylyl-sulfate kinase K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
D IT6_04245 sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D IT6_05260 bifunctional oligoribonuclease/PAP phosphatase NrnA K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
D IT6_04240 phosphoadenylyl-sulfate reductase K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D IT6_03360 molybdopterin-dependent oxidoreductase K05301 sorA; sulfite dehydrogenase (cytochrome) subunit A [EC:1.8.2.1]
D IT6_07310 flavodoxin domain-containing protein K00380 cysJ; sulfite reductase (NADPH) flavoprotein alpha-component [EC:1.8.1.2]
D IT6_08440 sulfite reductase subunit alpha K00380 cysJ; sulfite reductase (NADPH) flavoprotein alpha-component [EC:1.8.1.2]
D IT6_09045 NADPH-dependent assimilatory sulfite reductase hemoprotein subunit K00392 sir; sulfite reductase (ferredoxin) [EC:1.8.7.1]
D IT6_05310 NAD(P)/FAD-dependent oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D IT6_01120 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D IT6_04135 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D IT6_06440 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D IT6_07355 cysK; cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47]
D IT6_03680 selenium-binding protein K17285 SELENBP1; methanethiol oxidase [EC:1.8.3.4]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:mcao00061]
D IT6_09110 acetyl-CoA carboxylase carboxyltransferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D IT6_09165 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D IT6_07890 accC; acetyl-CoA carboxylase biotin carboxylase subunit K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D IT6_09095 acetyl-CoA carboxylase carboxyltransferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D IT6_08155 acyl carrier protein K02078 acpP; acyl carrier protein
D IT6_08165 ACP S-malonyltransferase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D IT6_00770 ketoacyl-ACP synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D IT6_08150 fabF; beta-ketoacyl-ACP synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D IT6_08160 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D IT6_03015 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D IT6_05215 bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/3-hydroxyacyl-ACP dehydratase K16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]
D IT6_09195 enoyl-ACP reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:mcao00071]
D IT6_08720 AMP-binding protein K05939 aas; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20]
D IT6_00425 FAD-dependent oxidoreductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]
D IT6_07540 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D IT6_08300 zinc-dependent alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:mcao00561]
D IT6_08905 glpK; glycerol kinase GlpK K00864 glpK; glycerol kinase [EC:2.7.1.30]
D IT6_00775 plsX; phosphate acyltransferase PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D IT6_07180 plsY; glycerol-3-phosphate 1-O-acyltransferase PlsY K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D IT6_01445 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D IT6_09745 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D IT6_01860 glycosyltransferase K03429 ugtP; processive 1,2-diacylglycerol beta-glucosyltransferase [EC:2.4.1.315]
C 00564 Glycerophospholipid metabolism [PATH:mcao00564]
D IT6_07175 NAD(P)-dependent glycerol-3-phosphate dehydrogenase K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D IT6_07180 plsY; glycerol-3-phosphate 1-O-acyltransferase PlsY K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D IT6_01445 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D IT6_09745 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D IT6_08720 AMP-binding protein K05939 aas; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20]
D IT6_06505 phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]
D IT6_06515 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
D IT6_06510 phosphatidylserine decarboxylase family protein K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]
D IT6_05585 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995 PGS1; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
D IT6_07150 CDP-alcohol phosphatidyltransferase family protein K08744 CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:mcao00230]
D IT6_05195 phospho-sugar mutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D IT6_03395 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D IT6_00760 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D IT6_08805 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D IT6_02415 phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D IT6_02985 purL; phosphoribosylformylglycinamidine synthase subunit PurL K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D IT6_05885 purS; phosphoribosylformylglycinamidine synthase subunit PurS K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D IT6_05890 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D IT6_00755 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D IT6_04870 5-(carboxyamino)imidazole ribonucleotide synthase K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D IT6_04875 purE; 5-(carboxyamino)imidazole ribonucleotide mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D IT6_10385 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D IT6_05880 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D IT6_01145 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D IT6_07345 adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D IT6_04635 polyphenol oxidase family protein K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D IT6_09135 hpt; hypoxanthine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
D IT6_07445 GuaB3 family IMP dehydrogenase-related protein K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D IT6_01175 non-canonical purine NTP pyrophosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D IT6_07440 guaA; glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D IT6_04885 gmk; guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D IT6_01345 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D IT6_01340 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D IT6_03565 ribonucleoside triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D IT6_06910 exopolyphosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
D IT6_07515 Ppx/GppA family phosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
D IT6_06495 adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D IT6_02705 hypothetical protein K01488 add; adenosine deaminase [EC:3.5.4.4]
D IT6_07590 TIGR00282 family metallophosphoesterase K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]
D IT6_02285 nucleoside monophosphate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D IT6_09755 mazG; nucleoside triphosphate pyrophosphohydrolase K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]
D IT6_02300 HIT domain-containing protein K19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53]
D IT6_04250 cysC; adenylyl-sulfate kinase K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
D IT6_04245 sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
C 00240 Pyrimidine metabolism [PATH:mcao00240]
D IT6_04440 carB; carbamoyl-phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D IT6_09715 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D IT6_09705 aspartate carbamoyltransferase catalytic subunit K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D IT6_09710 dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D IT6_06030 dihydroorotate dehydrogenase-like protein K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1]
D IT6_00040 dihydroorotate dehydrogenase-like protein K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1]
D IT6_07025 quinone-dependent dihydroorotate dehydrogenase K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]
D IT6_04315 orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D IT6_00435 pyrF; orotidine-5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D IT6_08465 UMP kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D IT6_09755 mazG; nucleoside triphosphate pyrophosphohydrolase K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]
D IT6_01840 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D IT6_01205 upp; uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D IT6_07590 TIGR00282 family metallophosphoesterase K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]
D IT6_00605 nucleoside deaminase K03365 FCY1; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21]
D IT6_03565 ribonucleoside triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D IT6_06825 dCTP deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D IT6_01345 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D IT6_01340 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D IT6_09175 tmk; dTMP kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D IT6_06935 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D IT6_03625 FAD-dependent oxidoreductase K17722 preT; dihydropyrimidine dehydrogenase (NAD+) subunit PreT [EC:1.3.1.1]
D IT6_03630 preA; NAD-dependent dihydropyrimidine dehydrogenase subunit PreA K17723 preA; dihydropyrimidine dehydrogenase (NAD+) subunit PreA [EC:1.3.1.1]
D IT6_03635 hydA; dihydropyrimidinase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D IT6_03640 M20 family metallo-hydrolase K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:mcao00250]
D IT6_00145 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D IT6_01990 nadB; L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D IT6_00255 alanine--glyoxylate aminotransferase family protein K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D IT6_08690 ald; alanine dehydrogenase K00259 ald; alanine dehydrogenase [EC:1.4.1.1]
D IT6_09800 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D IT6_06240 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D IT6_06495 adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D IT6_05880 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D IT6_09705 aspartate carbamoyltransferase catalytic subunit K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D IT6_06905 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D IT6_01635 aspartate aminotransferase family protein K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D IT6_08795 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D IT6_08675 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D IT6_03005 putA; bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
D IT6_00820 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D IT6_04440 carB; carbamoyl-phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D IT6_09715 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D IT6_05890 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D IT6_07170 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D IT6_00760 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:mcao00260]
D IT6_05060 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D IT6_10100 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D IT6_02910 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D IT6_06155 thrB; homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39]
D IT6_00600 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D IT6_02915 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D IT6_09090 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D IT6_00255 alanine--glyoxylate aminotransferase family protein K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D IT6_03720 gpmA; 2,3-diphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D IT6_00570 phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D IT6_10120 8-amino-7-oxononanoate synthase K00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]
D IT6_05350 gcvP; aminomethyl-transferring glycine dehydrogenase K00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]
D IT6_05340 gcvT; glycine cleavage system aminomethyltransferase GcvT K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D IT6_06755 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_00830 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01660 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_05345 gcvH; glycine cleavage system protein GcvH K02437 gcvH; glycine cleavage system H protein
D IT6_06515 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
D IT6_05780 tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D IT6_04890 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
C 00270 Cysteine and methionine metabolism [PATH:mcao00270]
D IT6_06440 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D IT6_07355 cysK; cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47]
D IT6_09245 bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase K24042 yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
D IT6_07505 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D IT6_03375 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D IT6_08025 nucleoside phosphorylase K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9]
D IT6_04635 polyphenol oxidase family protein K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D IT6_10115 amidohydrolase family protein K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D IT6_03370 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D IT6_05060 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D IT6_10100 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D IT6_02910 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D IT6_00590 NIL domain-containing protein K23976 K23976; L-aspartate semialdehyde sulfurtransferase ferredoxin
D IT6_07245 ilvE; branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D IT6_00145 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D IT6_01120 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D IT6_04135 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D IT6_00130 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D IT6_00570 phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
C 00280 Valine, leucine and isoleucine degradation [PATH:mcao00280]
D IT6_07245 ilvE; branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D IT6_06755 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_00830 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01660 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01665 NAD(P)-dependent oxidoreductase K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]
D IT6_02790 NAD(P)-dependent oxidoreductase K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]
D IT6_01635 aspartate aminotransferase family protein K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:mcao00290]
D IT6_02920 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D IT6_09700 3-isopropylmalate dehydratase K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D IT6_09695 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D IT6_05990 ilvB; biosynthetic-type acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D IT6_08735 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D IT6_08740 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D IT6_05700 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D IT6_07245 ilvE; branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D IT6_04700 citramalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D IT6_08745 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00300 Lysine biosynthesis [PATH:mcao00300]
D IT6_02910 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D IT6_05060 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D IT6_10100 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D IT6_04400 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D IT6_04395 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D IT6_05955 acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D IT6_08050 ArgE/DapE family deacylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D IT6_04405 diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D IT6_07575 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]
D IT6_01335 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D IT6_10315 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D IT6_10320 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
C 00310 Lysine degradation [PATH:mcao00310]
D IT6_06750 odhB; 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D IT6_06755 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_00830 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01660 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01635 aspartate aminotransferase family protein K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D IT6_08795 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D IT6_03955 lhgO; L-2-hydroxyglutarate oxidase K15736 lhgO; (S)-2-hydroxyglutarate dehydrogenase [EC:1.1.5.13]
D IT6_06525 KamA family radical SAM protein K01843 kamA; lysine 2,3-aminomutase [EC:5.4.3.2]
C 00220 Arginine biosynthesis [PATH:mcao00220]
D IT6_05950 argF; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D IT6_09800 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D IT6_06240 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D IT6_05890 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D IT6_00820 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D IT6_04440 carB; carbamoyl-phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D IT6_09715 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D IT6_08675 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D IT6_00145 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D IT6_07615 argA; amino-acid N-acetyltransferase K14682 argAB; amino-acid N-acetyltransferase [EC:2.3.1.1]
D IT6_05965 argJ; bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]
D IT6_05960 argB; acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8]
D IT6_05970 N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]
D IT6_05955 acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
C 00330 Arginine and proline metabolism [PATH:mcao00330]
D IT6_00605 nucleoside deaminase K03365 FCY1; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21]
D IT6_03760 hydantoinase/oxoprolinase family protein K01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14]
D IT6_03750 hydantoinase B/oxoprolinase family protein K01474 hyuB; N-methylhydantoinase B [EC:3.5.2.14]
D IT6_05120 speA; biosynthetic arginine decarboxylase K01585 speA; arginine decarboxylase [EC:4.1.1.19]
D IT6_01805 agmatine deiminase family protein K10536 aguA; agmatine deiminase [EC:3.5.3.12]
D IT6_01810 carbon-nitrogen hydrolase K12251 aguB; N-carbamoylputrescine amidase [EC:3.5.1.53]
D IT6_01875 aspartate aminotransferase family protein K00819 rocD; ornithine--oxo-acid transaminase [EC:2.6.1.13]
D IT6_07195 pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
D IT6_03005 putA; bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
D IT6_02340 proB; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D IT6_02335 glutamate-5-semialdehyde dehydrogenase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
D IT6_00145 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00340 Histidine metabolism [PATH:mcao00340]
D IT6_02305 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D IT6_06685 hisI; phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
D IT6_04415 hisA; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D IT6_04410 hisH; imidazole glycerol phosphate synthase subunit HisH K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D IT6_05750 hisF; imidazole glycerol phosphate synthase subunit HisF K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D IT6_06000 hisB; imidazoleglycerol-phosphate dehydratase HisB K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D IT6_07265 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D IT6_08205 histidinol-phosphatase HisJ family protein K04486 E3.1.3.15B; histidinol-phosphatase (PHP family) [EC:3.1.3.15]
D IT6_01780 histidinol-phosphatase HisJ family protein K04486 E3.1.3.15B; histidinol-phosphatase (PHP family) [EC:3.1.3.15]
D IT6_07435 hisD; histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
C 00350 Tyrosine metabolism [PATH:mcao00350]
D IT6_00145 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D IT6_07265 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D IT6_08345 aldehyde dehydrogenase family protein K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39]
D IT6_07540 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D IT6_08300 zinc-dependent alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D IT6_08795 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D IT6_05985 phenylpyruvate tautomerase K07253 MIF; phenylpyruvate tautomerase [EC:5.3.2.1]
C 00360 Phenylalanine metabolism [PATH:mcao00360]
D IT6_08345 aldehyde dehydrogenase family protein K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39]
D IT6_00145 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D IT6_07265 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D IT6_05985 phenylpyruvate tautomerase K07253 MIF; phenylpyruvate tautomerase [EC:5.3.2.1]
D IT6_06380 non-heme iron oxygenase ferredoxin subunit K05710 hcaC; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component
D IT6_00425 FAD-dependent oxidoreductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]
C 00380 Tryptophan metabolism
D IT6_06750 odhB; 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D IT6_06755 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_00830 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01660 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:mcao00400]
D IT6_00215 3-deoxy-7-phosphoheptulonate synthase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D IT6_02070 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]
D IT6_05205 aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D IT6_08870 type I 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D IT6_06450 shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D IT6_07190 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D IT6_01450 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D IT6_07185 aroC; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D IT6_08665 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D IT6_08670 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D IT6_09720 trpD; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D IT6_04895 phosphoribosylanthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D IT6_04900 trpC; indole-3-glycerol phosphate synthase TrpC K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D IT6_05780 tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D IT6_04890 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D IT6_01820 ACT domain-containing protein K14170 pheA; chorismate mutase / prephenate dehydratase [EC:5.4.99.5 4.2.1.51]
D IT6_07260 prephenate dehydrogenase/arogenate dehydrogenase family protein K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D IT6_00145 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D IT6_07265 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:mcao00410]
D IT6_06905 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D IT6_01635 aspartate aminotransferase family protein K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D IT6_05095 panC; pantoate--beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
D IT6_03625 FAD-dependent oxidoreductase K17722 preT; dihydropyrimidine dehydrogenase (NAD+) subunit PreT [EC:1.3.1.1]
D IT6_03630 preA; NAD-dependent dihydropyrimidine dehydrogenase subunit PreA K17723 preA; dihydropyrimidine dehydrogenase (NAD+) subunit PreA [EC:1.3.1.1]
D IT6_03635 hydA; dihydropyrimidinase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D IT6_03640 M20 family metallo-hydrolase K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
C 00430 Taurine and hypotaurine metabolism [PATH:mcao00430]
D IT6_06905 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D IT6_08690 ald; alanine dehydrogenase K00259 ald; alanine dehydrogenase [EC:1.4.1.1]
D IT6_07660 acetate/propionate family kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
C 00440 Phosphonate and phosphinate metabolism
D IT6_05690 MBL fold metallo-hydrolase K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]
C 00450 Selenocompound metabolism [PATH:mcao00450]
D IT6_09245 bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase K24042 yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
D IT6_07505 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D IT6_07650 SufS family cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D IT6_01470 trxB; thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D IT6_04250 cysC; adenylyl-sulfate kinase K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
D IT6_04245 sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D IT6_06790 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism [PATH:mcao00460]
D IT6_07140 bglX; beta-glucosidase BglX K05349 bglX; beta-glucosidase [EC:3.2.1.21]
D IT6_09090 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:mcao00470]
D IT6_06760 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D IT6_10350 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D IT6_05890 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D IT6_05635 murD; UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D IT6_04405 diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D IT6_01335 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D IT6_08480 FAD-binding oxidoreductase K19746 dauA; D-arginine dehydrogenase [EC:1.4.99.6]
C 00480 Glutathione metabolism [PATH:mcao00480]
D IT6_05160 leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D IT6_01920 NADP-dependent isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D IT6_07235 gndA; NADP-dependent phosphogluconate dehydrogenase K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D IT6_07520 zwf; glucose-6-phosphate dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D IT6_09975 zwf; glucose-6-phosphate dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis [PATH:mcao00540]
D IT6_05210 lpxA; acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
D IT6_07340 lpxA; acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
D IT6_05215 bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/3-hydroxyacyl-ACP dehydratase K16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]
D IT6_02905 lpxD; UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]
D IT6_08255 lpxI; UDP-2,3-diacylglucosamine diphosphatase LpxI K09949 lpxI; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]
D IT6_08265 lpxB; lipid-A-disaccharide synthase K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]
D IT6_04290 lpxK; tetraacyldisaccharide 4'-kinase K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]
D IT6_03410 KpsF/GutQ family sugar-phosphate isomerase K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]
D IT6_01845 kdsA; 3-deoxy-8-phosphooctulonate synthase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]
D IT6_01835 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]
D IT6_08765 3-deoxy-D-manno-octulosonic acid transferase K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]
D IT6_05770 acyloxyacyl hydrolase K12976 pagL; lipid A 3-O-deacylase [EC:3.1.1.-]
D IT6_09160 SIS domain-containing protein K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
D IT6_01825 D-glycero-beta-D-manno-heptose-7-phosphate kinase K21344 rfaE1; D-glycero-beta-D-manno-heptose-7-phosphate kinase [EC:2.7.1.167]
D IT6_01830 HAD-IIIA family hydrolase K03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83]
D IT6_02420 adenylyltransferase/cytidyltransferase family protein K21345 rfaE2; D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase [EC:2.7.7.70]
D IT6_08325 rfaD; ADP-glyceromanno-heptose 6-epimerase K03274 gmhD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20]
D IT6_07365 glycosyltransferase family 9 protein K02841 waaC; lipopolysaccharide heptosyltransferase I [EC:2.4.99.23]
D IT6_04295 waaF; lipopolysaccharide heptosyltransferase II K02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24]
D IT6_01795 glycosyltransferase family 9 protein K02849 waaQ; lipopolysaccharide heptosyltransferase III [EC:2.4.99.25]
D IT6_08640 glycosyltransferase family 4 protein K02844 waaG; UDP-glucose:(heptosyl)LPS alpha-1,3-glucosyltransferase [EC:2.4.1.-]
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:mcao00541]
D IT6_08225 galE; UDP-glucose 4-epimerase GalE K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D IT6_06490 UDP-glucose/GDP-mannose dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D IT6_04060 GDP-mannose 4,6-dehydratase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
D IT6_05645 nucleotidyltransferase family protein K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D IT6_06070 rfbA; glucose-1-phosphate thymidylyltransferase RfbA K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D IT6_06075 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D IT6_00160 SDR family oxidoreductase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D IT6_03965 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D IT6_03975 glucose-1-phosphate cytidylyltransferase K00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33]
D IT6_08445 class I mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D IT6_08490 mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D IT6_05605 NAD-dependent epimerase/dehydratase family protein K02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271]
D IT6_04110 DegT/DnrJ/EryC1/StrS aminotransferase family protein K13010 per; perosamine synthetase [EC:2.6.1.102]
D IT6_10290 UDP-N-acetylglucosamine diphosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
C 00550 Peptidoglycan biosynthesis [PATH:mcao00550]
D IT6_08130 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D IT6_10345 murC; UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D IT6_05635 murD; UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D IT6_05640 hypothetical protein K23170 murL; UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase [EC:5.1.1.23]
D IT6_10315 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D IT6_10350 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D IT6_10320 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D IT6_06500 isoprenyl transferase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D IT6_02320 undecaprenyl-diphosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D IT6_10110 phosphatase PAP2 family protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
D IT6_10325 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D IT6_10340 murG; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D IT6_08850 mrdA; penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D IT6_10310 penicillin-binding protein 2 K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D IT6_09895 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D IT6_02315 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C 00552 Teichoic acid biosynthesis [PATH:mcao00552]
D IT6_02320 undecaprenyl-diphosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D IT6_10110 phosphatase PAP2 family protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
D IT6_01860 glycosyltransferase K03429 ugtP; processive 1,2-diacylglycerol beta-glucosyltransferase [EC:2.4.1.315]
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis [PATH:mcao00543]
D IT6_06440 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:mcao00730]
D IT6_06740 thiC; phosphomethylpyrimidine synthase ThiC K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D IT6_09665 thiD; bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]
D IT6_06435 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_00805 aminotransferase class V-fold PLP-dependent enzyme K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_01790 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_02490 aminotransferase class V-fold PLP-dependent enzyme K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_04145 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_04860 thiH; 2-iminoacetate synthase ThiH K03150 thiH; 2-iminoacetate synthase [EC:4.1.99.19]
D IT6_09795 1-deoxy-D-xylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
D IT6_06115 thiazole synthase K03149 thiG; thiazole synthase [EC:2.8.1.10]
D IT6_07895 thiE; thiamine phosphate synthase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D IT6_06775 thiL; thiamine-phosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D IT6_02285 nucleoside monophosphate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:mcao00740]
D IT6_06260 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
D IT6_09130 ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D IT6_09115 ribH; 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D IT6_06080 riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D IT6_05270 bifunctional riboflavin kinase/FAD synthetase K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]
D IT6_04380 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00750 Vitamin B6 metabolism [PATH:mcao00750]
D IT6_01040 pdxH; pyridoxamine 5'-phosphate oxidase K00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5]
D IT6_02840 pyridoxine 5'-phosphate synthase K03474 pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2]
D IT6_00600 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D IT6_02915 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
C 00760 Nicotinate and nicotinamide metabolism [PATH:mcao00760]
D IT6_01990 nadB; L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D IT6_06475 nadA; quinolinate synthase NadA K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D IT6_06165 nadC; carboxylating nicotinate-nucleotide diphosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D IT6_02200 nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D IT6_00175 nadD; nicotinate (nicotinamide) nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]
D IT6_09755 mazG; nucleoside triphosphate pyrophosphohydrolase K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]
D IT6_02965 NAD(+) synthase K01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]
D IT6_04960 NAD(+)/NADH kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D IT6_10010 NAD(P) transhydrogenase subunit alpha K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1]
D IT6_10015 Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1]
D IT6_10005 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta K00325 pntB; proton-translocating NAD(P)+ transhydrogenase subunit beta [EC:7.1.1.1]
D IT6_08795 NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00770 Pantothenate and CoA biosynthesis [PATH:mcao00770]
D IT6_05990 ilvB; biosynthetic-type acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D IT6_08735 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D IT6_08740 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D IT6_05700 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D IT6_07805 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D IT6_07415 2-dehydropantoate 2-reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D IT6_05095 panC; pantoate--beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
D IT6_08900 type III pantothenate kinase K03525 coaX; type III pantothenate kinase [EC:2.7.1.33]
D IT6_09865 phosphopantothenoylcysteine synthase K21977 coaB; phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5]
D IT6_04880 phosphopantothenoylcysteine synthase K01598 PPCDC; phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36]
D IT6_09755 mazG; nucleoside triphosphate pyrophosphohydrolase K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]
D IT6_08125 coaD; pantetheine-phosphate adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D IT6_08215 dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]
D IT6_02845 acpS; holo-ACP synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
D IT6_07245 ilvE; branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D IT6_03625 FAD-dependent oxidoreductase K17722 preT; dihydropyrimidine dehydrogenase (NAD+) subunit PreT [EC:1.3.1.1]
D IT6_03630 preA; NAD-dependent dihydropyrimidine dehydrogenase subunit PreA K17723 preA; dihydropyrimidine dehydrogenase (NAD+) subunit PreA [EC:1.3.1.1]
D IT6_03635 hydA; dihydropyrimidinase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D IT6_03640 M20 family metallo-hydrolase K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
C 00780 Biotin metabolism [PATH:mcao00780]
D IT6_08150 fabF; beta-ketoacyl-ACP synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D IT6_08160 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D IT6_03015 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D IT6_09195 enoyl-ACP reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D IT6_10125 bioA; adenosylmethionine--8-amino-7-oxononanoate transaminase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
D IT6_01060 bioD; dethiobiotin synthase K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3]
D IT6_01115 bioB; biotin synthase BioB K01012 bioB; biotin synthase [EC:2.8.1.6]
D IT6_09205 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:mcao00785]
D IT6_08685 lipoate--protein ligase family protein K23734 lipM; lipoyl(octanoyl) transferase [EC:2.3.1.181]
D IT6_09860 lipA; lipoyl synthase K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D IT6_06755 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_00830 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01660 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01640 pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D IT6_01645 alpha-ketoacid dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D IT6_01655 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D IT6_06745 2-oxoglutarate dehydrogenase E1 component K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
D IT6_06750 odhB; 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D IT6_05350 gcvP; aminomethyl-transferring glycine dehydrogenase K00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]
D IT6_05340 gcvT; glycine cleavage system aminomethyltransferase GcvT K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D IT6_05345 gcvH; glycine cleavage system protein GcvH K02437 gcvH; glycine cleavage system H protein
C 00790 Folate biosynthesis [PATH:mcao00790]
D IT6_06735 GTP cyclohydrolase I FolE2 K09007 folE2; GTP cyclohydrolase IB [EC:3.5.4.16]
D IT6_03665 alkaline phosphatase D family protein K01113 phoD; alkaline phosphatase D [EC:3.1.3.1]
D IT6_07800 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D IT6_05995 dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D IT6_04335 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D IT6_07955 bifunctional folylpolyglutamate synthase/dihydrofolate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
D IT6_06260 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
D IT6_05665 anthranilate synthase component I family protein K01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85]
D IT6_02970 aminotransferase class IV K02619 pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38]
D IT6_00390 queD; 6-carboxytetrahydropterin synthase QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D IT6_01670 4a-hydroxytetrahydrobiopterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D IT6_00420 radical SAM protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D IT6_04265 moaA; GTP 3',8-cyclase MoaA K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D IT6_06675 moaC; cyclic pyranopterin monophosphate synthase MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D IT6_04255 molybdenum cofactor biosynthesis protein MoaE K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D IT6_06680 mog; molybdopterin adenylyltransferase K03831 mogA; molybdopterin adenylyltransferase [EC:2.7.7.75]
D IT6_01765 molybdopterin molybdotransferase MoeA K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D IT6_01775 mobA; molybdenum cofactor guanylyltransferase K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
C 00670 One carbon pool by folate [PATH:mcao00670]
D IT6_07925 formate--tetrahydrofolate ligase K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
D IT6_02350 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D IT6_09090 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D IT6_02415 phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D IT6_01145 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D IT6_07110 methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D IT6_05340 gcvT; glycine cleavage system aminomethyltransferase GcvT K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D IT6_09245 bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase K24042 yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
D IT6_06935 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D IT6_03020 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:mcao00860]
D IT6_07155 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D IT6_05430 glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D IT6_04345 hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D IT6_01200 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D IT6_05425 hemC; hydroxymethylbilane synthase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D IT6_02050 chlorite dismutase family protein K00435 hemQ; hydrogen peroxide-dependent heme synthase [EC:1.3.98.5]
D IT6_05420 cobA; uroporphyrinogen-III C-methyltransferase K13542 cobA-hemD; uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
D IT6_10245 cyoE; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D IT6_10250 COX15/CtaA family protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D IT6_07605 sirohydrochlorin ferrochelatase K03795 cbiX; sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
D IT6_08060 ferritin K22336 bfrB; bacterioferritin B [EC:1.16.3.1]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:mcao00130]
D IT6_04375 UbiA family prenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D IT6_04065 menaquinone biosynthesis decarboxylase K03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98]
D IT6_04380 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D IT6_01135 ubiquinone/menaquinone biosynthesis methyltransferase K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]
D IT6_04450 menaquinone biosynthesis protein K11782 mqnA; chorismate dehydratase [EC:4.2.1.151]
D IT6_04370 mqnE; aminofutalosine synthase MqnE K18285 mqnE; aminodeoxyfutalosine synthase [EC:2.5.1.120]
D IT6_04445 mqnC; dehypoxanthine futalosine cyclase K11784 mqnC; cyclic dehypoxanthinyl futalosine synthase [EC:1.21.98.1]
D IT6_06120 ABC transporter substrate-binding protein K11785 mqnD; 5,8-dihydroxy-2-naphthoate synthase [EC:4.1.99.29]
D IT6_00365 wrbA; NAD(P)H:quinone oxidoreductase K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:mcao00900]
D IT6_09795 1-deoxy-D-xylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
D IT6_04665 1-deoxy-D-xylulose-5-phosphate reductoisomerase K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]
D IT6_02455 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60]
D IT6_00430 ispE; 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]
D IT6_02785 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase K01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12]
D IT6_04655 ispG; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]
D IT6_05165 4-hydroxy-3-methylbut-2-enyl diphosphate reductase K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]
D IT6_04380 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D IT6_08010 polyprenyl synthetase family protein K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D IT6_02015 polyprenyl synthetase family protein K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D IT6_06500 isoprenyl transferase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D IT6_09250 M48 family metallopeptidase K06013 STE24; STE24 endopeptidase [EC:3.4.24.84]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis [PATH:mcao00909]
D IT6_08020 shc; squalene--hopene cyclase K06045 shc; squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:5.4.99.17 4.2.1.129]
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D IT6_00545 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
D IT6_08585 class I SAM-dependent methyltransferase K19569 elmMIII; 8-demethyl-8-(2,3-dimethoxy-alpha-L-rhamnosyl)tetracenomycin-C 4'-O-methyltransferase [EC:2.1.1.307]
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis [PATH:mcao00523]
D IT6_05645 nucleotidyltransferase family protein K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D IT6_06070 rfbA; glucose-1-phosphate thymidylyltransferase RfbA K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D IT6_01180 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D IT6_06075 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D IT6_00160 SDR family oxidoreductase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D IT6_03965 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
D IT6_06075 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D IT6_00160 SDR family oxidoreductase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids [PATH:mcao00946]
D IT6_07140 bglX; beta-glucosidase BglX K05349 bglX; beta-glucosidase [EC:3.2.1.21]
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis [PATH:mcao00332]
D IT6_02340 proB; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D IT6_02335 glutamate-5-semialdehyde dehydrogenase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
C 00261 Monobactam biosynthesis [PATH:mcao00261]
D IT6_04250 cysC; adenylyl-sulfate kinase K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
D IT6_04245 sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D IT6_05060 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D IT6_10100 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D IT6_04400 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D IT6_04395 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:mcao00521]
D IT6_04800 glk; glucokinase K00845 glk; glucokinase [EC:2.7.1.2]
D IT6_05195 phospho-sugar mutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D IT6_05905 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D IT6_05645 nucleotidyltransferase family protein K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D IT6_06070 rfbA; glucose-1-phosphate thymidylyltransferase RfbA K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D IT6_01180 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D IT6_06075 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D IT6_00160 SDR family oxidoreductase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D IT6_03965 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
D IT6_04800 glk; glucokinase K00845 glk; glucokinase [EC:2.7.1.2]
C 00525 Acarbose and validamycin biosynthesis [PATH:mcao00525]
D IT6_05645 nucleotidyltransferase family protein K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D IT6_06070 rfbA; glucose-1-phosphate thymidylyltransferase RfbA K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D IT6_01180 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D IT6_06075 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D IT6_00160 SDR family oxidoreductase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C 00401 Novobiocin biosynthesis [PATH:mcao00401]
D IT6_07260 prephenate dehydrogenase/arogenate dehydrogenase family protein K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D IT6_00145 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D IT6_07265 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D IT6_08665 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D IT6_08670 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D IT6_08165 ACP S-malonyltransferase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D IT6_08160 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D IT6_03015 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D IT6_09195 enoyl-ACP reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
D IT6_08155 acyl carrier protein K02078 acpP; acyl carrier protein
C 00999 Biosynthesis of various plant secondary metabolites [PATH:mcao00999]
D IT6_03375 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D IT6_06450 shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D IT6_07140 bglX; beta-glucosidase BglX K05349 bglX; beta-glucosidase [EC:3.2.1.21]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation
D IT6_00425 FAD-dependent oxidoreductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]
C 00627 Aminobenzoate degradation [PATH:mcao00627]
D IT6_08730 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D IT6_04380 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D IT6_08695 NAD(P)H-dependent oxidoreductase K23529 E1.6.5.7; 2-hydroxy-1,4-benzoquinone reductase [EC:1.6.5.7]
C 00364 Fluorobenzoate degradation [PATH:mcao00364]
D IT6_08680 dienelactone hydrolase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
C 00625 Chloroalkane and chloroalkene degradation [PATH:mcao00625]
D IT6_07540 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D IT6_08300 zinc-dependent alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D IT6_04220 nifK; nitrogenase molybdenum-iron protein subunit beta K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]
D IT6_04230 nifH; nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH
D IT6_04225 nifD; nitrogenase molybdenum-iron protein alpha chain K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1]
C 00361 Chlorocyclohexane and chlorobenzene degradation [PATH:mcao00361]
D IT6_08680 dienelactone hydrolase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
D IT6_08695 NAD(P)H-dependent oxidoreductase K23529 E1.6.5.7; 2-hydroxy-1,4-benzoquinone reductase [EC:1.6.5.7]
C 00623 Toluene degradation [PATH:mcao00623]
D IT6_08680 dienelactone hydrolase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation [PATH:mcao00633]
D IT6_03940 alkene reductase K10680 nemA; N-ethylmaleimide reductase [EC:1.-.-.-]
D IT6_00310 nickel-dependent hydrogenase large subunit K06281 hyaB; hydrogenase large subunit [EC:1.12.99.6]
D IT6_00305 hydrogenase small subunit K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6]
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
D IT6_08345 aldehyde dehydrogenase family protein K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39]
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation [PATH:mcao00626]
D IT6_07540 alcohol dehydrogenase catalytic domain-containing protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D IT6_08300 zinc-dependent alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:mcao03020]
D IT6_02360 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D IT6_02355 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D IT6_10195 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D IT6_01155 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
C 03022 Basal transcription factors
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:mcao03010]
D IT6_01425 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D IT6_07880 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D IT6_03270 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D IT6_10190 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D IT6_03215 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D IT6_02880 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D IT6_03315 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D IT6_03230 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D IT6_05975 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D IT6_03305 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D IT6_10185 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D IT6_03320 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D IT6_10180 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D IT6_03235 type Z 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D IT6_05190 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D IT6_00475 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D IT6_03255 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D IT6_01605 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D IT6_03280 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D IT6_10165 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D IT6_08295 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D IT6_02375 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D IT6_03285 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D IT6_03300 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D IT6_03295 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D IT6_03240 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D IT6_03225 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D IT6_02365 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D IT6_02890 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D IT6_02370 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D IT6_02380 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D IT6_05980 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D IT6_03250 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D IT6_03210 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D IT6_03265 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D IT6_10200 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D IT6_03220 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D IT6_00485 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D IT6_04670 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D IT6_00515 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D IT6_03275 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D IT6_03290 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D IT6_03245 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D IT6_02870 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D IT6_00510 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D IT6_01610 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D IT6_03260 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D IT6_08145 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D IT6_00780 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D IT6_02450 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D IT6_02010 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D IT6_04675 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D IT6_10175 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D IT6_01940 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:mcao00970]
D IT6_07155 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D IT6_08935 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D IT6_03585 amidase K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D IT6_08930 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D IT6_08940 gatC; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D IT6_03465 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D IT6_06805 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D IT6_00630 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D IT6_04685 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D IT6_08835 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D IT6_09180 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D IT6_06790 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D IT6_07110 methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D IT6_09780 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D IT6_08035 leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D IT6_07910 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D IT6_00385 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D IT6_10160 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D IT6_08945 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D IT6_06800 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D IT6_07915 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D IT6_05710 pheT; phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D IT6_09680 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D IT6_08885 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:mcao03060]
D IT6_03205 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D IT6_02390 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D IT6_01530 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D IT6_04455 secD; protein translocase subunit SecD K12257 secDF; SecD/SecF fusion protein
D IT6_04460 yajC; preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D IT6_01995 yidC; membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D IT6_09730 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D IT6_00470 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D IT6_09125 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D IT6_04650 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D IT6_02210 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
D IT6_07930 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D IT6_06470 lspA; signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:mcao04122]
D IT6_06435 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_00805 aminotransferase class V-fold PLP-dependent enzyme K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_01790 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_02490 aminotransferase class V-fold PLP-dependent enzyme K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_04145 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_01120 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D IT6_04135 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D IT6_01495 mnmA; tRNA 2-thiouridine(34) synthase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D IT6_04255 molybdenum cofactor biosynthesis protein MoaE K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D IT6_04265 moaA; GTP 3',8-cyclase MoaA K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D IT6_00595 MoaD/ThiS family protein K03636 moaD; sulfur-carrier protein
D IT6_04260 MoaD/ThiS family protein K03636 moaD; sulfur-carrier protein
D IT6_03450 moeB; molybdopterin-synthase adenylyltransferase MoeB K21147 moeZR; sulfur-carrier protein adenylyltransferase/sulfurtransferase [EC:2.7.7.80 2.7.7.- 2.8.1.11 2.8.1.-]
D IT6_06675 moaC; cyclic pyranopterin monophosphate synthase MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D IT6_06680 mog; molybdopterin adenylyltransferase K03831 mogA; molybdopterin adenylyltransferase [EC:2.7.7.75]
D IT6_04865 thiS; sulfur carrier protein ThiS K03154 thiS; sulfur carrier protein
C 03050 Proteasome [PATH:mcao03050]
D IT6_00440 AAA family ATPase K13527 mpa; proteasome-associated ATPase
D IT6_00460 proteasome subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D IT6_00455 proteasome subunit alpha K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C 03018 RNA degradation [PATH:mcao03018]
D IT6_07705 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D IT6_05185 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D IT6_08220 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D IT6_05385 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D IT6_05375 groL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D IT6_10205 ppk1; polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:mcao03030]
D IT6_02065 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D IT6_09075 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D IT6_09170 DNA replication protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D IT6_06460 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D IT6_06110 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D IT6_09765 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D IT6_02885 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D IT6_00490 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D IT6_00205 ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4]
D IT6_08920 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03410 Base excision repair [PATH:mcao03410]
D IT6_01880 3-methyladenine DNA glycosylase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D IT6_08170 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D IT6_00210 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D IT6_00705 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
D IT6_00610 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D IT6_01075 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D IT6_08920 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:mcao03420]
D IT6_07630 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D IT6_05465 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
D IT6_07760 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
D IT6_08460 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
D IT6_02980 excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
D IT6_02060 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D IT6_08920 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03430 Mismatch repair [PATH:mcao03430]
D IT6_06930 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D IT6_06560 mutL; DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL
D IT6_02060 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D IT6_02410 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D IT6_09790 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D IT6_02885 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D IT6_02065 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D IT6_06460 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D IT6_09075 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D IT6_09170 DNA replication protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D IT6_08920 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03440 Homologous recombination [PATH:mcao03440]
D IT6_02885 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D IT6_09065 recR; recombination protein RecR K06187 recR; recombination protein RecR
D IT6_09775 recA; recombinase RecA K03553 recA; recombination protein RecA
D IT6_04010 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D IT6_04005 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D IT6_04015 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D IT6_00200 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D IT6_02065 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D IT6_06460 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D IT6_09075 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D IT6_09170 DNA replication protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D IT6_06615 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
C 03450 Non-homologous end-joining
D IT6_09320 Ku protein K10979 ku; DNA end-binding protein Ku
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:mcao02010]
D IT6_01255 ABC transporter substrate-binding protein K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4]
D IT6_01715 modA; molybdate ABC transporter substrate-binding protein K02020 modA; molybdate transport system substrate-binding protein
D IT6_01710 modB; molybdate ABC transporter permease subunit K02018 modB; molybdate transport system permease protein
D IT6_01705 ATP-binding cassette domain-containing protein K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15]
D IT6_02460 MCE family protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D IT6_02470 ABC transporter permease K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D IT6_02465 ATP-binding cassette domain-containing protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D IT6_08000 pstS; phosphate ABC transporter substrate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D IT6_07995 pstC; phosphate ABC transporter permease subunit PstC K02037 pstC; phosphate transport system permease protein
D IT6_07990 pstA; phosphate ABC transporter permease PstA K02038 pstA; phosphate transport system permease protein
D IT6_07985 pstB; phosphate ABC transporter ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D IT6_01535 peptide ABC transporter substrate-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D IT6_08235 ABC transporter permease K15581 oppB; oligopeptide transport system permease protein
D IT6_08230 ABC transporter permease K15582 oppC; oligopeptide transport system permease protein
D IT6_09220 zinc ABC transporter substrate-binding protein K09815 znuA; zinc transport system substrate-binding protein
D IT6_09230 metal ABC transporter permease K09816 znuB; zinc transport system permease protein
D IT6_09225 metal ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D IT6_07255 ABC transporter permease K09808 lolC_E; lipoprotein-releasing system permease protein
D IT6_05445 LptF/LptG family permease K11720 lptG; lipopolysaccharide export system permease protein
D IT6_09155 LptF/LptG family permease K11720 lptG; lipopolysaccharide export system permease protein
D IT6_02055 lptB; LPS export ABC transporter ATP-binding protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]
D IT6_04565 ATP-binding cassette domain-containing protein K19340 nosF; Cu-processing system ATP-binding protein
D IT6_10050 ABC transporter ATP-binding protein K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]
D IT6_10375 ABC transporter ATP-binding protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump
C 02060 Phosphotransferase system (PTS) [PATH:mcao02060]
D IT6_05650 ptsP; phosphoenolpyruvate--protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D IT6_05655 HPr family phosphocarrier protein K02784 ptsH; phosphocarrier protein HPr
D IT6_04955 PTS sugar transporter subunit IIA K02768 fruB; fructose PTS system EIIA component [EC:2.7.1.202]
C 03070 Bacterial secretion system [PATH:mcao03070]
D IT6_09905 TolC family outer membrane protein K12340 tolC; outer membrane protein
D IT6_10395 TolC family protein K12340 tolC; outer membrane protein
D IT6_00910 type II/IV secretion system protein K02454 gspE; general secretion pathway protein E [EC:7.4.2.8]
D IT6_04455 secD; protein translocase subunit SecD K12257 secDF; SecD/SecF fusion protein
D IT6_02390 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D IT6_01530 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D IT6_03205 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D IT6_04460 yajC; preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D IT6_01995 yidC; membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D IT6_09730 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D IT6_09125 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D IT6_00470 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D IT6_04650 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D IT6_02210 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:mcao02020]
D IT6_07085 PAS domain-containing protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D IT6_07090 response regulator K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
D IT6_03665 alkaline phosphatase D family protein K01113 phoD; alkaline phosphatase D [EC:3.1.3.1]
D IT6_08000 pstS; phosphate ABC transporter substrate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D IT6_08895 DegQ family serine endoprotease K04771 degP; serine protease Do [EC:3.4.21.107]
D IT6_00195 Do family serine endopeptidase K04771 degP; serine protease Do [EC:3.4.21.107]
D IT6_03715 HAMP domain-containing histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
D IT6_05475 response regulator transcription factor K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
D IT6_06860 efflux RND transporter periplasmic adaptor subunit K07798 cusB; membrane fusion protein, copper/silver efflux system
D IT6_06865 efflux RND transporter permease subunit K07787 cusA; copper/silver efflux system protein
D IT6_02865 sensor histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
D IT6_02860 response regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
D IT6_06605 kdpA; potassium-transporting ATPase subunit KdpA K01546 kdpA; potassium-transporting ATPase potassium-binding subunit
D IT6_06600 kdpB; potassium-transporting ATPase subunit KdpB K01547 kdpB; potassium-transporting ATPase ATP-binding subunit [EC:7.2.2.6]
D IT6_06595 kdpC; K(+)-transporting ATPase subunit C K01548 kdpC; potassium-transporting ATPase KdpC subunit
D IT6_10250 COX15/CtaA family protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D IT6_06455 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D IT6_05480 HAMP domain-containing histidine kinase K18351 vanSAc; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
D IT6_06940 fatty acid desaturase K10255 FAD6; acyl-lipid omega-6 desaturase (Delta-12 desaturase) [EC:1.14.19.23 1.14.19.45]
D IT6_02835 glnD; [protein-PII] uridylyltransferase K00990 glnD; [protein-PII] uridylyltransferase [EC:2.7.7.59]
D IT6_00825 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1
D IT6_01325 P-II family nitrogen regulator K04751 glnB; nitrogen regulatory protein P-II 1
D IT6_00820 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D IT6_04130 nifA; nif-specific transcriptional activator NifA K02584 nifA; Nif-specific regulatory protein
D IT6_03475 rpoN; RNA polymerase factor sigma-54 K03092 rpoN; RNA polymerase sigma-54 factor
D IT6_00305 hydrogenase small subunit K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6]
D IT6_00310 nickel-dependent hydrogenase large subunit K06281 hyaB; hydrogenase large subunit [EC:1.12.99.6]
D IT6_00315 cybH; Ni/Fe-hydrogenase, b-type cytochrome subunit K03620 hyaC; Ni/Fe-hydrogenase 1 B-type cytochrome subunit
D IT6_04550 cytochrome oxidase K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9]
D IT6_04545 cbb3-type cytochrome c oxidase subunit II K00405 ccoO; cytochrome c oxidase cbb3-type subunit II
D IT6_04515 hypothetical protein K00407 ccoQ; cytochrome c oxidase cbb3-type subunit IV
D IT6_09905 TolC family outer membrane protein K12340 tolC; outer membrane protein
D IT6_10395 TolC family protein K12340 tolC; outer membrane protein
D IT6_09565 SLBB domain-containing protein K01991 wza; polysaccharide biosynthesis/export protein
D IT6_07270 protein-tyrosine-phosphatase K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:mcao02024]
D IT6_08665 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D IT6_08670 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D IT6_00215 3-deoxy-7-phosphoheptulonate synthase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D IT6_02860 response regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
D IT6_06905 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
D IT6_09130 ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D IT6_01535 peptide ABC transporter substrate-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D IT6_08235 ABC transporter permease K15581 oppB; oligopeptide transport system permease protein
D IT6_08230 ABC transporter permease K15582 oppC; oligopeptide transport system permease protein
D IT6_05220 ABC transporter substrate-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D IT6_05250 ABC transporter permease K02033 ABC.PE.P; peptide/nickel transport system permease protein
D IT6_05245 ABC transporter permease K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D IT6_05240 ABC transporter ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D IT6_05235 ABC transporter ATP-binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein
D IT6_01995 yidC; membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D IT6_04455 secD; protein translocase subunit SecD K12257 secDF; SecD/SecF fusion protein
D IT6_02390 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D IT6_01530 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D IT6_03205 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D IT6_04460 yajC; preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D IT6_09730 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D IT6_09125 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D IT6_00470 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
D IT6_08290 OmpA family protein K02557 motB; chemotaxis protein MotB
C 02040 Flagellar assembly [PATH:mcao02040]
D IT6_08290 OmpA family protein K02557 motB; chemotaxis protein MotB
D IT6_07350 RNA polymerase sigma factor RpoD/SigA K03086 rpoD; RNA polymerase primary sigma factor
D IT6_09770 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor
D IT6_03475 rpoN; RNA polymerase factor sigma-54 K03092 rpoN; RNA polymerase sigma-54 factor
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D IT6_07705 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance [PATH:mcao01501]
D IT6_08725 glycoside hydrolase family 3 protein K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]
D IT6_01535 peptide ABC transporter substrate-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D IT6_08235 ABC transporter permease K15581 oppB; oligopeptide transport system permease protein
D IT6_08230 ABC transporter permease K15582 oppC; oligopeptide transport system permease protein
D IT6_09905 TolC family outer membrane protein K12340 tolC; outer membrane protein
D IT6_10395 TolC family protein K12340 tolC; outer membrane protein
D IT6_08850 mrdA; penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D IT6_10310 penicillin-binding protein 2 K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
C 01502 Vancomycin resistance [PATH:mcao01502]
D IT6_05480 HAMP domain-containing histidine kinase K18351 vanSAc; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
D IT6_10350 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D IT6_06760 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D IT6_10320 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D IT6_10325 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D IT6_10340 murG; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:mcao01503]
D IT6_05090 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D IT6_09855 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D IT6_08895 DegQ family serine endoprotease K04771 degP; serine protease Do [EC:3.4.21.107]
D IT6_00195 Do family serine endopeptidase K04771 degP; serine protease Do [EC:3.4.21.107]
D IT6_09905 TolC family outer membrane protein K12340 tolC; outer membrane protein
D IT6_10395 TolC family protein K12340 tolC; outer membrane protein
D IT6_05210 lpxA; acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
D IT6_07340 lpxA; acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:mcao01000]
C 01001 Protein kinases [BR:mcao01001]
D IT6_09560 polysaccharide biosynthesis tyrosine autokinase K16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3]
D IT6_07085 PAS domain-containing protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D IT6_03715 HAMP domain-containing histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
D IT6_02865 sensor histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
D IT6_05480 HAMP domain-containing histidine kinase K18351 vanSAc; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:mcao01009]
D IT6_03370 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
C 01002 Peptidases and inhibitors [BR:mcao01002]
D IT6_06470 lspA; signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36]
D IT6_07440 guaA; glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D IT6_03935 type 1 glutamine amidotransferase K07010 K07010; putative glutamine amidotransferase
D IT6_00760 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D IT6_05785 gltB; glutamate synthase large subunit K00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]
D IT6_07170 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D IT6_08475 DJ-1/PfpI family protein K05520 yhbO; deglycase [EC:3.5.1.124]
D IT6_05575 DJ-1/PfpI family protein K03152 thiJ; protein deglycase [EC:3.5.1.124]
D IT6_04710 M3 family oligoendopeptidase K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
D IT6_04275 insulinase family protein K07263 pqqL; zinc protease [EC:3.4.24.-]
D IT6_05160 leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D IT6_08050 ArgE/DapE family deacylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D IT6_10170 map; type I methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D IT6_05455 aminopeptidase P family protein K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D IT6_01080 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D IT6_04365 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D IT6_09250 M48 family metallopeptidase K06013 STE24; STE24 endopeptidase [EC:3.4.24.84]
D IT6_08800 htpX; protease HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D IT6_04660 rseP; RIP metalloprotease RseP K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
D IT6_03840 biotin/lipoyl-binding protein K16922 yydH; putative peptide zinc metalloprotease protein
D IT6_08895 DegQ family serine endoprotease K04771 degP; serine protease Do [EC:3.4.21.107]
D IT6_00195 Do family serine endopeptidase K04771 degP; serine protease Do [EC:3.4.21.107]
D IT6_09895 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D IT6_02315 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D IT6_01485 clpP; ATP-dependent Clp endopeptidase proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D IT6_05860 umuD; translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D IT6_07930 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D IT6_08830 carboxy terminal-processing peptidase K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
D IT6_06785 sppA; signal peptide peptidase SppA K04773 sppA; protease IV [EC:3.4.21.-]
D IT6_06160 rhomboid family intramembrane serine protease K07059 K07059; rhomboid family protein
D IT6_00295 rhomboid family intramembrane serine protease K07059 K07059; rhomboid family protein
D IT6_00460 proteasome subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D IT6_00455 proteasome subunit alpha K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D IT6_08045 TldD/PmbA family protein K03568 tldD; TldD protein
C 01003 Glycosyltransferases [BR:mcao01003]
D IT6_04730 glycosyltransferase K14335 pimC; alpha-1,6-mannosyltransferase [EC:2.4.1.-]
D IT6_00815 glycosyltransferase K14335 pimC; alpha-1,6-mannosyltransferase [EC:2.4.1.-]
D IT6_01860 glycosyltransferase K03429 ugtP; processive 1,2-diacylglycerol beta-glucosyltransferase [EC:2.4.1.315]
D IT6_05935 glgA; glycogen synthase GlgA K00703 glgA; starch synthase [EC:2.4.1.21]
D IT6_09300 mdoH; glucans biosynthesis glucosyltransferase MdoH K03669 mdoH; membrane glycosyltransferase [EC:2.4.1.-]
C 01005 Lipopolysaccharide biosynthesis proteins [BR:mcao01005]
D IT6_05210 lpxA; acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
D IT6_07340 lpxA; acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
D IT6_08265 lpxB; lipid-A-disaccharide synthase K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]
D IT6_05215 bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/3-hydroxyacyl-ACP dehydratase K16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]
D IT6_02905 lpxD; UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]
D IT6_08255 lpxI; UDP-2,3-diacylglucosamine diphosphatase LpxI K09949 lpxI; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]
D IT6_04290 lpxK; tetraacyldisaccharide 4'-kinase K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]
D IT6_08765 3-deoxy-D-manno-octulosonic acid transferase K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]
D IT6_05770 acyloxyacyl hydrolase K12976 pagL; lipid A 3-O-deacylase [EC:3.1.1.-]
D IT6_01845 kdsA; 3-deoxy-8-phosphooctulonate synthase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]
D IT6_01835 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]
D IT6_03410 KpsF/GutQ family sugar-phosphate isomerase K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]
D IT6_01825 D-glycero-beta-D-manno-heptose-7-phosphate kinase K21344 rfaE1; D-glycero-beta-D-manno-heptose-7-phosphate kinase [EC:2.7.1.167]
D IT6_02420 adenylyltransferase/cytidyltransferase family protein K21345 rfaE2; D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase [EC:2.7.7.70]
D IT6_07365 glycosyltransferase family 9 protein K02841 waaC; lipopolysaccharide heptosyltransferase I [EC:2.4.99.23]
D IT6_04295 waaF; lipopolysaccharide heptosyltransferase II K02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24]
D IT6_08640 glycosyltransferase family 4 protein K02844 waaG; UDP-glucose:(heptosyl)LPS alpha-1,3-glucosyltransferase [EC:2.4.1.-]
D IT6_01795 glycosyltransferase family 9 protein K02849 waaQ; lipopolysaccharide heptosyltransferase III [EC:2.4.99.25]
D IT6_09160 SIS domain-containing protein K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
D IT6_01830 HAD-IIIA family hydrolase K03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83]
D IT6_08325 rfaD; ADP-glyceromanno-heptose 6-epimerase K03274 gmhD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:mcao01011]
D IT6_08130 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D IT6_10345 murC; UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D IT6_05635 murD; UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D IT6_10315 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D IT6_10350 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D IT6_06760 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D IT6_10325 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D IT6_10340 murG; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D IT6_02320 undecaprenyl-diphosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D IT6_10110 phosphatase PAP2 family protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
D IT6_04300 murJ; murein biosynthesis integral membrane protein MurJ K03980 murJ; putative peptidoglycan lipid II flippase
D IT6_08850 mrdA; penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D IT6_10310 penicillin-binding protein 2 K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D IT6_09895 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D IT6_02315 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D IT6_06880 lytic transglycosylase domain-containing protein K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D IT6_01300 septal ring lytic transglycosylase RlpA family protein K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D IT6_05090 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D IT6_09855 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
C 01004 Lipid biosynthesis proteins [BR:mcao01004]
D IT6_08165 ACP S-malonyltransferase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D IT6_00770 ketoacyl-ACP synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D IT6_08150 fabF; beta-ketoacyl-ACP synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D IT6_08160 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D IT6_03015 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D IT6_05215 bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/3-hydroxyacyl-ACP dehydratase K16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]
D IT6_09195 enoyl-ACP reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D IT6_06940 fatty acid desaturase K10255 FAD6; acyl-lipid omega-6 desaturase (Delta-12 desaturase) [EC:1.14.19.23 1.14.19.45]
D IT6_07130 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D IT6_00775 plsX; phosphate acyltransferase PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D IT6_07180 plsY; glycerol-3-phosphate 1-O-acyltransferase PlsY K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D IT6_01445 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D IT6_09745 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 01008 Polyketide biosynthesis proteins [BR:mcao01008]
D IT6_08585 class I SAM-dependent methyltransferase K19569 elmMIII; 8-demethyl-8-(2,3-dimethoxy-alpha-L-rhamnosyl)tetracenomycin-C 4'-O-methyltransferase [EC:2.1.1.307]
C 01006 Prenyltransferases [BR:mcao01006]
D IT6_08010 polyprenyl synthetase family protein K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D IT6_02015 polyprenyl synthetase family protein K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D IT6_06500 isoprenyl transferase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D IT6_07330 miaA; tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D IT6_04375 UbiA family prenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D IT6_10245 cyoE; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
C 01007 Amino acid related enzymes [BR:mcao01007]
D IT6_07155 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D IT6_09680 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D IT6_08885 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D IT6_09180 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D IT6_10160 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D IT6_06790 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D IT6_07910 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D IT6_09780 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D IT6_08035 leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D IT6_00385 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D IT6_06805 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D IT6_06800 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D IT6_00630 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D IT6_08835 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D IT6_08945 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D IT6_04685 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D IT6_03465 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D IT6_07915 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D IT6_05710 pheT; phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D IT6_00145 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D IT6_07575 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]
D IT6_03385 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K10907 K10907; aminotransferase [EC:2.6.1.-]
D IT6_07265 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D IT6_10120 8-amino-7-oxononanoate synthase K00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]
D IT6_01875 aspartate aminotransferase family protein K00819 rocD; ornithine--oxo-acid transaminase [EC:2.6.1.13]
D IT6_05955 acetylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D IT6_01635 aspartate aminotransferase family protein K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D IT6_10125 bioA; adenosylmethionine--8-amino-7-oxononanoate transaminase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
D IT6_04345 hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D IT6_07245 ilvE; branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D IT6_00255 alanine--glyoxylate aminotransferase family protein K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D IT6_04110 DegT/DnrJ/EryC1/StrS aminotransferase family protein K13010 per; perosamine synthetase [EC:2.6.1.102]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:mcao00194]
D IT6_06220 atpC; ATP synthase F1 subunit epsilon K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D IT6_02190 hypothetical protein K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D IT6_06215 atpD; F0F1 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D IT6_02195 F0F1 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D IT6_06210 atpG; ATP synthase F1 subunit gamma K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D IT6_02160 F0F1 ATP synthase subunit gamma K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D IT6_06205 F0F1 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D IT6_02165 F0F1 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D IT6_06195 atpF; F0F1 ATP synthase subunit B K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D IT6_02170 F0F1 ATP synthase subunit delta K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D IT6_06190 ATPase K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D IT6_02175 atpE; ATP synthase F0 subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D IT6_06185 atpB; F0F1 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D IT6_02180 F0F1 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D IT6_02185 AtpZ/AtpI family protein K02116 atpI; ATP synthase protein I
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:mcao03000]
D IT6_01250 LysR family transcriptional regulator K21703 cbbR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator
D IT6_09040 GntR family transcriptional regulator K03710 K03710; GntR family transcriptional regulator
D IT6_01890 MerR family transcriptional regulator K19057 merD; MerR family transcriptional regulator, mercuric resistance operon regulatory protein
D IT6_04190 heavy metal-responsive transcriptional regulator K19591 cueR; MerR family transcriptional regulator, copper efflux regulator
D IT6_07865 transcriptional repressor K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D IT6_00720 Crp/Fnr family transcriptional regulator K21563 dnr; CRP/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator
D IT6_09620 helix-turn-helix transcriptional regulator K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D IT6_01550 metal-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D IT6_09205 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D IT6_09430 sigma-54-dependent Fis family transcriptional regulator K21405 acoR; sigma-54 dependent transcriptional regulator, acetoin dehydrogenase operon transcriptional activator AcoR
D IT6_04130 nifA; nif-specific transcriptional activator NifA K02584 nifA; Nif-specific regulatory protein
D IT6_03005 putA; bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
D IT6_06550 ParB/RepB/Spo0J family partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D IT6_06570 transcriptional activator RfaH K05785 rfaH; transcriptional antiterminator RfaH
D IT6_00790 nrdR; transcriptional repressor NrdR K07738 nrdR; transcriptional repressor NrdR
D IT6_10295 division/cell wall cluster transcriptional repressor MraZ K03925 mraZ; transcriptional regulator MraZ
C 03021 Transcription machinery [BR:mcao03021]
D IT6_10195 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D IT6_02360 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D IT6_02355 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D IT6_01155 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D IT6_07350 RNA polymerase sigma factor RpoD/SigA K03086 rpoD; RNA polymerase primary sigma factor
D IT6_09770 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor
D IT6_08275 sigma-70 family RNA polymerase sigma factor K03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily
D IT6_03475 rpoN; RNA polymerase factor sigma-54 K03092 rpoN; RNA polymerase sigma-54 factor
D IT6_08250 nusA; transcription termination factor NusA K02600 nusA; transcription termination/antitermination protein NusA
D IT6_09120 nusB; transcription antitermination factor NusB K03625 nusB; transcription antitermination protein NusB
D IT6_02385 nusG; transcription termination/antitermination factor NusG K02601 nusG; transcription termination/antitermination protein NusG
D IT6_08220 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
C 03019 Messenger RNA biogenesis [BR:mcao03019]
D IT6_08840 Rne/Rng family ribonuclease K08301 rng; ribonuclease G [EC:3.1.26.-]
D IT6_01190 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D IT6_10390 HD domain-containing protein K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-]
D IT6_07705 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D IT6_05185 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D IT6_08220 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D IT6_05385 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D IT6_05375 groL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D IT6_10205 ppk1; polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
C 03041 Spliceosome
C 03011 Ribosome [BR:mcao03011]
D IT6_01425 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D IT6_07880 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D IT6_03270 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D IT6_10190 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D IT6_03215 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D IT6_02880 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D IT6_03315 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D IT6_03230 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D IT6_05975 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D IT6_03305 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D IT6_10185 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D IT6_03320 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D IT6_10180 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D IT6_03235 type Z 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D IT6_05190 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D IT6_00475 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D IT6_03255 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D IT6_01605 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D IT6_03280 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D IT6_10165 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D IT6_08295 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D IT6_02375 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D IT6_03285 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D IT6_03300 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D IT6_03295 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D IT6_03240 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D IT6_03225 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D IT6_02890 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D IT6_02370 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D IT6_02380 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D IT6_02365 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D IT6_05980 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D IT6_03250 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D IT6_03210 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D IT6_03265 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D IT6_10200 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D IT6_03220 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D IT6_00485 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D IT6_04670 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D IT6_00515 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D IT6_03275 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D IT6_03290 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D IT6_03245 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D IT6_00510 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D IT6_01610 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D IT6_03260 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D IT6_08145 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D IT6_00780 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D IT6_02450 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D IT6_02010 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D IT6_04675 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D IT6_10175 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D IT6_02870 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D IT6_01940 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:mcao03009]
D IT6_01190 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D IT6_00505 obgE; GTPase ObgE K03979 obgE; GTPase [EC:3.6.5.-]
D IT6_08250 nusA; transcription termination factor NusA K02600 nusA; transcription termination/antitermination protein NusA
D IT6_09120 nusB; transcription antitermination factor NusB K03625 nusB; transcription antitermination protein NusB
D IT6_02385 nusG; transcription termination/antitermination factor NusG K02601 nusG; transcription termination/antitermination protein NusG
D IT6_07510 rsmA; ribosomal RNA small subunit methyltransferase A K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D IT6_03335 RsmD family RNA methyltransferase K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]
D IT6_08320 16S rRNA (uracil(1498)-N(3))-methyltransferase K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]
D IT6_10300 rsmH; 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D IT6_07475 rsmI; 16S rRNA (cytidine(1402)-2'-O)-methyltransferase K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]
D IT6_07755 TlyA family RNA methyltransferase K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]
D IT6_06530 class I SAM-dependent rRNA methyltransferase K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]
D IT6_05230 class I SAM-dependent methyltransferase K25136 rlmK; 23S rRNA (guanine2069-N7)-methyltransferase [EC:2.1.1.264]
D IT6_06830 rlmN; 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]
D IT6_07045 class I SAM-dependent RNA methyltransferase K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]
D IT6_06235 rRNA pseudouridine synthase K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]
D IT6_07545 RluA family pseudouridine synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D IT6_01070 RluA family pseudouridine synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D IT6_08175 rimO; 30S ribosomal protein S12 methylthiotransferase RimO K14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]
D IT6_08840 Rne/Rng family ribonuclease K08301 rng; ribonuclease G [EC:3.1.26.-]
D IT6_05775 ruvX; Holliday junction resolvase RuvX K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
D IT6_07145 der; ribosome biogenesis GTPase Der K03977 engA; GTPase
D IT6_07335 hflX; GTPase HflX K03665 hflX; GTPase
D IT6_07105 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D IT6_08240 rbfA; 30S ribosome-binding factor RbfA K02834 rbfA; ribosome-binding factor A
D IT6_00170 rsfS; ribosome silencing factor K09710 ybeB; ribosome-associated protein
D IT6_08710 ybeY; rRNA maturation RNase YbeY K07042 ybeY; probable rRNA maturation factor
D IT6_04705 raiA; ribosome-associated translation inhibitor RaiA K05808 hpf; ribosome hibernation promoting factor
D IT6_06565 ychF; redox-regulated ATPase YchF K06942 ychF; ribosome-binding ATPase
D IT6_00785 metal-binding protein K07040 yceD; DUF177 domain-containing protein
C 03016 Transfer RNA biogenesis [BR:mcao03016]
D IT6_05360 CCA tRNA nucleotidyltransferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
D IT6_07670 RtcB family protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D IT6_07675 archease K24956 ZBTB8OS; protein archease
D IT6_07155 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D IT6_08945 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D IT6_07910 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D IT6_08035 leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D IT6_06790 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D IT6_10160 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D IT6_00385 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D IT6_06805 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D IT6_03465 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D IT6_00630 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D IT6_04685 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D IT6_08835 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D IT6_09180 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D IT6_09780 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D IT6_06800 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D IT6_07915 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D IT6_05710 pheT; phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D IT6_09680 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D IT6_08885 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D IT6_00075 D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D IT6_00795 histidine triad nucleotide-binding protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D IT6_05720 methyltransferase domain-containing protein K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D IT6_05765 truA; tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D IT6_05265 truB; tRNA pseudouridine(55) synthase TruB K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D IT6_06435 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_00805 aminotransferase class V-fold PLP-dependent enzyme K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_01790 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_02490 aminotransferase class V-fold PLP-dependent enzyme K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_04145 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_07105 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D IT6_07330 miaA; tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D IT6_07020 mnmE; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D IT6_06105 mnmG; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D IT6_02005 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D IT6_06480 RNA ligase partner protein K09006 K09006; RNA-free ribonuclease P [EC:3.1.26.5]
D IT6_03455 ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
D IT6_05875 thpR; RNA 2',3'-cyclic phosphodiesterase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D IT6_05400 nucleoside deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
D IT6_02995 miaB; tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D IT6_05705 trmFO; methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]
D IT6_00480 trmD; tRNA (guanosine(37)-N1)-methyltransferase TrmD K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D IT6_05755 tRNA (cytidine(34)-2'-O)-methyltransferase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D IT6_01495 mnmA; tRNA 2-thiouridine(34) synthase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D IT6_04030 iron-sulfur cluster assembly accessory protein K13628 iscA; iron-sulfur cluster assembly protein
D IT6_04120 iron-sulfur cluster assembly accessory protein K13628 iscA; iron-sulfur cluster assembly protein
D IT6_04165 Fe-S cluster assembly scaffold protein SufA K13628 iscA; iron-sulfur cluster assembly protein
D IT6_05405 aminomethyltransferase K06980 ygfZ; tRNA-modifying protein YgfZ
D IT6_09035 queA; tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D IT6_00390 queD; 6-carboxytetrahydropterin synthase QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D IT6_00420 radical SAM protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D IT6_02205 epoxyqueuosine reductase QueH K09765 queH; epoxyqueuosine reductase [EC:1.17.99.6]
D IT6_04465 tgt; tRNA guanosine(34) transglycosylase Tgt K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D IT6_06765 tsaB; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D IT6_00155 tsaD; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D IT6_06770 tsaE; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D IT6_05185 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C 03012 Translation factors [BR:mcao03012]
D IT6_08245 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D IT6_04680 translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D IT6_07885 tsf; translation elongation factor Ts K02357 tsf; elongation factor Ts
D IT6_02400 tuf; elongation factor Tu K02358 tuf; elongation factor Tu
D IT6_03310 fusA; elongation factor G K02355 fusA; elongation factor G
D IT6_08140 prfA; peptide chain release factor 1 K02835 prfA; peptide chain release factor 1
D IT6_08470 frr; ribosome recycling factor K02838 frr; ribosome recycling factor
D IT6_08135 prmC; peptide chain release factor N(5)-glutamine methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D IT6_02875 aminoacyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D IT6_03405 efp; elongation factor P K02356 efp; elongation factor P
D IT6_06665 prfB; peptide chain release factor 2 K02836 prfB; peptide chain release factor 2
C 03110 Chaperones and folding catalysts [BR:mcao03110]
D IT6_06920 clpB; ATP-dependent chaperone ClpB K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D IT6_07425 ATP-dependent Clp protease ATP-binding subunit K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC
D IT6_08330 AAA family ATPase K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
D IT6_01490 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
D IT6_05385 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D IT6_05375 groL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D IT6_05670 dnaJ; molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ
D IT6_01885 J domain-containing protein K05516 cbpA; curved DNA-binding protein
D IT6_05675 nucleotide exchange factor GrpE K03687 GRPE; molecular chaperone GrpE
D IT6_08370 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein
D IT6_05380 groES; co-chaperone GroES K04078 groES; chaperonin GroES
D IT6_08895 DegQ family serine endoprotease K04771 degP; serine protease Do [EC:3.4.21.107]
D IT6_00195 Do family serine endopeptidase K04771 degP; serine protease Do [EC:3.4.21.107]
D IT6_01080 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D IT6_04365 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D IT6_06185 atpB; F0F1 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D IT6_02180 F0F1 ATP synthase subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D IT6_09280 hypA; hydrogenase maturation nickel metallochaperone HypA K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF
D IT6_08530 hypB; hydrogenase nickel incorporation protein HypB K04652 hypB; hydrogenase nickel incorporation protein HypB
D IT6_09150 SurA N-terminal domain-containing protein K03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]
D IT6_05035 peptidylprolyl isomerase K03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]
D IT6_06960 peptidylprolyl isomerase K03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]
D IT6_01090 trxA; thioredoxin K03671 TXN; thioredoxin
D IT6_07205 trxA; thioredoxin K05838 ybbN; putative thioredoxin
D IT6_00615 glutaredoxin K07390 grxD; monothiol glutaredoxin
C 04131 Membrane trafficking [BR:mcao04131]
D IT6_01515 gap; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D IT6_03720 gpmA; 2,3-diphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D IT6_06065 hypothetical protein K00873 PK; pyruvate kinase [EC:2.7.1.40]
D IT6_06810 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D IT6_04910 MFS transporter K06902 UMF1; MFS transporter, UMF1 family
D IT6_04915 MFS transporter K06902 UMF1; MFS transporter, UMF1 family
D IT6_03030 lipid-binding SYLF domain-containing protein K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
D IT6_04070 lipid-binding SYLF domain-containing protein K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
C 04121 Ubiquitin system
C 03051 Proteasome [BR:mcao03051]
D IT6_00460 proteasome subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D IT6_00455 proteasome subunit alpha K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D IT6_00440 AAA family ATPase K13527 mpa; proteasome-associated ATPase
D IT6_00465 proteasome accessory factor PafA2 family protein K13571 pafA; proteasome accessory factor A [EC:6.3.1.19]
D IT6_00445 proteasome accessory factor PafA2 family protein K20814 dop; Pup amidohydrolase [EC:3.5.1.119]
C 03032 DNA replication proteins [BR:mcao03032]
D IT6_05365 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D IT6_06795 integration host factor subunit beta K04764 ihfA; integration host factor subunit alpha
D IT6_06455 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D IT6_06110 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D IT6_09765 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D IT6_02885 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D IT6_02065 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D IT6_06460 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D IT6_09170 DNA replication protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D IT6_09075 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D IT6_00490 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D IT6_00205 ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4]
D IT6_08920 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D IT6_07100 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D IT6_07095 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D IT6_02080 DNA topoisomerase 3 K03169 topB; DNA topoisomerase III [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:mcao03036]
D IT6_01190 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D IT6_05365 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D IT6_06795 integration host factor subunit beta K04764 ihfA; integration host factor subunit alpha
D IT6_01885 J domain-containing protein K05516 cbpA; curved DNA-binding protein
D IT6_06455 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D IT6_10360 ftsA; cell division protein FtsA K03590 ftsA; cell division protein FtsA
D IT6_10310 penicillin-binding protein 2 K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D IT6_08185 DNA translocase FtsK 4TM domain-containing protein K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family
D IT6_10335 FtsW/RodA/SpoVE family cell cycle protein K03588 ftsW; cell division protein FtsW
D IT6_05090 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D IT6_09855 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D IT6_08865 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D IT6_08860 mreC; rod shape-determining protein MreC K03570 mreC; rod shape-determining protein MreC
D IT6_08845 rod shape-determining protein RodA K05837 rodA; rod shape determining protein RodA
D IT6_08065 ParA family protein K03496 parA; chromosome partitioning protein
D IT6_06550 ParB/RepB/Spo0J family partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D IT6_06105 mnmG; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D IT6_05705 trmFO; methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]
D IT6_08760 tyrosine-type recombinase/integrase K03733 xerC; integrase/recombinase XerC
D IT6_01185 tyrosine recombinase K04763 xerD; integrase/recombinase XerD
D IT6_00110 Mrp/NBP35 family ATP-binding protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
C 03400 DNA repair and recombination proteins [BR:mcao03400]
D IT6_05225 MGMT family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D IT6_00705 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
D IT6_00210 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D IT6_01880 3-methyladenine DNA glycosylase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D IT6_08170 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D IT6_05915 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D IT6_00610 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D IT6_01075 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D IT6_09305 endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D IT6_08920 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D IT6_05465 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
D IT6_07760 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
D IT6_08460 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
D IT6_02980 excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
D IT6_02060 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D IT6_02360 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D IT6_02355 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D IT6_10195 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D IT6_01155 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D IT6_07630 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D IT6_06930 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D IT6_06560 mutL; DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL
D IT6_02410 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D IT6_09790 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D IT6_02065 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D IT6_06460 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D IT6_09170 DNA replication protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D IT6_09075 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D IT6_02885 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D IT6_09775 recA; recombinase RecA K03553 recA; recombination protein RecA
D IT6_04010 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D IT6_04005 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D IT6_04015 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D IT6_06615 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D IT6_00200 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D IT6_09065 recR; recombination protein RecR K06187 recR; recombination protein RecR
D IT6_06660 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D IT6_02225 UvrD-helicase domain-containing protein K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D IT6_05805 cas1d; type I-D CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D IT6_02710 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D IT6_09320 Ku protein K10979 ku; DNA end-binding protein Ku
D IT6_07100 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D IT6_07095 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D IT6_05365 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D IT6_06795 integration host factor subunit beta K04764 ihfA; integration host factor subunit alpha
D IT6_05865 Y-family DNA polymerase K03502 umuC; DNA polymerase V
D IT6_05860 umuD; translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D IT6_04340 polX; DNA polymerase/3'-5' exonuclease PolX K02347 polX; DNA polymerase (family X)
D IT6_07570 DEAD/DEAH box helicase family protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D IT6_01345 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D IT6_01340 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D IT6_05260 bifunctional oligoribonuclease/PAP phosphatase NrnA K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
C 03029 Mitochondrial biogenesis [BR:mcao03029]
D IT6_08245 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D IT6_04680 translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D IT6_07885 tsf; translation elongation factor Ts K02357 tsf; elongation factor Ts
D IT6_02400 tuf; elongation factor Tu K02358 tuf; elongation factor Tu
D IT6_03310 fusA; elongation factor G K02355 fusA; elongation factor G
D IT6_09680 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D IT6_08035 leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D IT6_06805 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D IT6_00630 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D IT6_10160 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D IT6_08935 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D IT6_03585 amidase K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D IT6_08930 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D IT6_08940 gatC; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D IT6_02885 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D IT6_02895 bamA; outer membrane protein assembly factor BamA K07277 SAM50; outer membrane protein insertion porin family
D IT6_05385 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D IT6_05675 nucleotide exchange factor GrpE K03687 GRPE; molecular chaperone GrpE
D IT6_05375 groL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D IT6_05380 groES; co-chaperone GroES K04078 groES; chaperonin GroES
D IT6_05670 dnaJ; molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ
D IT6_06435 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_00805 aminotransferase class V-fold PLP-dependent enzyme K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_01790 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_02490 aminotransferase class V-fold PLP-dependent enzyme K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_04145 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_00615 glutaredoxin K07390 grxD; monothiol glutaredoxin
D IT6_00110 Mrp/NBP35 family ATP-binding protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D IT6_10245 cyoE; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D IT6_10250 COX15/CtaA family protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D IT6_01995 yidC; membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D IT6_08780 SCO family protein K07152 SCO1; protein SCO1
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:mcao02000]
D IT6_10050 ABC transporter ATP-binding protein K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]
D IT6_10375 ABC transporter ATP-binding protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump
D IT6_01715 modA; molybdate ABC transporter substrate-binding protein K02020 modA; molybdate transport system substrate-binding protein
D IT6_01710 modB; molybdate ABC transporter permease subunit K02018 modB; molybdate transport system permease protein
D IT6_01255 ABC transporter substrate-binding protein K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4]
D IT6_01705 ATP-binding cassette domain-containing protein K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15]
D IT6_02460 MCE family protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D IT6_02470 ABC transporter permease K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D IT6_02465 ATP-binding cassette domain-containing protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D IT6_08000 pstS; phosphate ABC transporter substrate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D IT6_07995 pstC; phosphate ABC transporter permease subunit PstC K02037 pstC; phosphate transport system permease protein
D IT6_07990 pstA; phosphate ABC transporter permease PstA K02038 pstA; phosphate transport system permease protein
D IT6_07985 pstB; phosphate ABC transporter ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D IT6_07375 transporter substrate-binding domain-containing protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D IT6_01535 peptide ABC transporter substrate-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D IT6_08235 ABC transporter permease K15581 oppB; oligopeptide transport system permease protein
D IT6_08230 ABC transporter permease K15582 oppC; oligopeptide transport system permease protein
D IT6_05220 ABC transporter substrate-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D IT6_05250 ABC transporter permease K02033 ABC.PE.P; peptide/nickel transport system permease protein
D IT6_05245 ABC transporter permease K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D IT6_05240 ABC transporter ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D IT6_05235 ABC transporter ATP-binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein
D IT6_09220 zinc ABC transporter substrate-binding protein K09815 znuA; zinc transport system substrate-binding protein
D IT6_09230 metal ABC transporter permease K09816 znuB; zinc transport system permease protein
D IT6_09225 metal ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D IT6_05445 LptF/LptG family permease K11720 lptG; lipopolysaccharide export system permease protein
D IT6_09155 LptF/LptG family permease K11720 lptG; lipopolysaccharide export system permease protein
D IT6_02055 lptB; LPS export ABC transporter ATP-binding protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]
D IT6_04565 ATP-binding cassette domain-containing protein K19340 nosF; Cu-processing system ATP-binding protein
D IT6_08075 ABC transporter permease subunit K25151 gldF; gliding motility-associated transport system permease protein
D IT6_08070 ATP-binding cassette domain-containing protein K25152 gldA; gliding motility-associated transport system ATP-binding protein
D IT6_08080 GldG family protein K25153 gldG; gliding motility-associatede transport system auxiliary component
D IT6_09925 ABC transporter permease K25180 ybhR; drug efflux transport system permease protein
D IT6_09920 ABC transporter permease K25181 ybhS; drug efflux transport system permease protein
D IT6_09915 ABC transporter ATP-binding protein K25182 ybhF; drug efflux transport system ATP-binding protein
D IT6_09910 efflux RND transporter periplasmic adaptor subunit K25183 ybhG; membrane fusion protein YbhG
D IT6_07255 ABC transporter permease K09808 lolC_E; lipoprotein-releasing system permease protein
D IT6_08775 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein
D IT6_00085 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein
D IT6_08770 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D IT6_00080 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D IT6_06310 FtsX-like permease family protein K02004 ABC.CD.P; putative ABC transport system permease protein
D IT6_06315 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D IT6_07250 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D IT6_06400 sufC; Fe-S cluster assembly ATPase SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein
D IT6_01280 NarK/NasA family nitrate transporter K02575 NRT2; MFS transporter, NNP family, nitrate/nitrite transporter
D IT6_05285 MFS transporter K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein
D IT6_07710 DHA2 family efflux MFS transporter permease subunit K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein
D IT6_02090 MFS transporter K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein
D IT6_02095 MFS transporter K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein
D IT6_04910 MFS transporter K06902 UMF1; MFS transporter, UMF1 family
D IT6_04915 MFS transporter K06902 UMF1; MFS transporter, UMF1 family
D IT6_05650 ptsP; phosphoenolpyruvate--protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D IT6_05655 HPr family phosphocarrier protein K02784 ptsH; phosphocarrier protein HPr
D IT6_04955 PTS sugar transporter subunit IIA K02768 fruB; fructose PTS system EIIA component [EC:2.7.1.202]
D IT6_03670 aquaporin K06188 aqpZ; aquaporin Z
D IT6_00165 potassium channel protein K10716 kch; voltage-gated potassium channel
D IT6_01350 ammonium transporter K03320 amt; ammonium transporter, Amt family
D IT6_06360 VWA domain-containing protein K07114 yfbK; Ca-activated chloride channel homolog
D IT6_10265 VWA domain-containing protein K07114 yfbK; Ca-activated chloride channel homolog
D IT6_08290 OmpA family protein K02557 motB; chemotaxis protein MotB
D IT6_05925 MotA/TolQ/ExbB proton channel family protein K03561 exbB; biopolymer transport protein ExbB
D IT6_07465 MotA/TolQ/ExbB proton channel family protein K03561 exbB; biopolymer transport protein ExbB
D IT6_08650 MotA/TolQ/ExbB proton channel family protein K03561 exbB; biopolymer transport protein ExbB
D IT6_02030 MotA/TolQ/ExbB proton channel family protein K03561 exbB; biopolymer transport protein ExbB
D IT6_02280 MotA/TolQ/ExbB proton channel family protein K03561 exbB; biopolymer transport protein ExbB
D IT6_05920 biopolymer transporter ExbD K03559 exbD; biopolymer transport protein ExbD
D IT6_06335 biopolymer transporter ExbD K03559 exbD; biopolymer transport protein ExbD
D IT6_07460 biopolymer transporter ExbD K03559 exbD; biopolymer transport protein ExbD
D IT6_08655 biopolymer transporter ExbD K03559 exbD; biopolymer transport protein ExbD
D IT6_02035 biopolymer transporter ExbD K03559 exbD; biopolymer transport protein ExbD
D IT6_02275 biopolymer transporter ExbD K03559 exbD; biopolymer transport protein ExbD
D IT6_06330 MotA/TolQ/ExbB proton channel family protein K03562 tolQ; biopolymer transport protein TolQ
D IT6_07950 HlyC/CorC family transporter K03699 tlyC; magnesium and cobalt exporter, CNNM family
D IT6_05490 TonB-dependent receptor plug domain-containing protein K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D IT6_07040 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D IT6_02665 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D IT6_03725 TolC family protein K15725 czcC; outer membrane protein, heavy metal efflux system
D IT6_03730 TolC family protein K15725 czcC; outer membrane protein, heavy metal efflux system
D IT6_09905 TolC family outer membrane protein K12340 tolC; outer membrane protein
D IT6_10395 TolC family protein K12340 tolC; outer membrane protein
D IT6_05280 efflux transporter outer membrane subunit K18903 oprC; outer membrane protein, multidrug efflux system
D IT6_05460 efflux transporter outer membrane subunit K18903 oprC; outer membrane protein, multidrug efflux system
D IT6_09565 SLBB domain-containing protein K01991 wza; polysaccharide biosynthesis/export protein
D IT6_02895 bamA; outer membrane protein assembly factor BamA K07277 SAM50; outer membrane protein insertion porin family
D IT6_01855 hypothetical protein K09774 lptA; lipopolysaccharide export system protein LptA
D IT6_04920 efflux RND transporter permease subunit K15726 czcA; heavy metal efflux system protein
D IT6_03740 efflux RND transporter permease subunit K15726 czcA; heavy metal efflux system protein
D IT6_06865 efflux RND transporter permease subunit K07787 cusA; copper/silver efflux system protein
D IT6_07500 hypothetical protein K07300 chaA; Ca2+:H+ antiporter
D IT6_09685 SulP family inorganic anion transporter K03321 TC.SULP; sulfate permease, SulP family
D IT6_01555 Nramp family divalent metal transporter K03322 mntH; manganese transport protein
D IT6_09615 arsB; ACR3 family arsenite efflux transporter K03325 ACR3; arsenite transporter
D IT6_04300 murJ; murein biosynthesis integral membrane protein MurJ K03980 murJ; putative peptidoglycan lipid II flippase
D IT6_06015 VIT1/CCC1 transporter family protein K22736 VIT; vacuolar iron transporter family protein
D IT6_10335 FtsW/RodA/SpoVE family cell cycle protein K03588 ftsW; cell division protein FtsW
D IT6_04810 energy transducer TonB K03832 tonB; periplasmic protein TonB
D IT6_05485 energy transducer TonB K03832 tonB; periplasmic protein TonB
D IT6_08660 energy transducer TonB K03832 tonB; periplasmic protein TonB
D IT6_06350 OmpA family protein K03640 pal; peptidoglycan-associated lipoprotein
D IT6_06345 PD40 domain-containing protein K03641 tolB; TolB protein
D IT6_05525 sodium-translocating pyrophosphatase K15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1]
D IT6_05290 HlyD family efflux transporter periplasmic adaptor subunit K03543 emrA; membrane fusion protein, multidrug efflux system
D IT6_08100 HlyD family secretion protein K03543 emrA; membrane fusion protein, multidrug efflux system
D IT6_02105 efflux RND transporter periplasmic adaptor subunit K03543 emrA; membrane fusion protein, multidrug efflux system
D IT6_03200 HlyD family secretion protein K03543 emrA; membrane fusion protein, multidrug efflux system
D IT6_06860 efflux RND transporter periplasmic adaptor subunit K07798 cusB; membrane fusion protein, copper/silver efflux system
D IT6_03850 efflux RND transporter periplasmic adaptor subunit K18990 vexE; membrane fusion protein, multidrug efflux system
D IT6_09560 polysaccharide biosynthesis tyrosine autokinase K16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3]
D IT6_01440 ferrous iron transport protein A K04758 feoA; ferrous iron transport protein A
D IT6_01435 feoB; ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B
C 02044 Secretion system [BR:mcao02044]
D IT6_09905 TolC family outer membrane protein K12340 tolC; outer membrane protein
D IT6_10395 TolC family protein K12340 tolC; outer membrane protein
D IT6_00910 type II/IV secretion system protein K02454 gspE; general secretion pathway protein E [EC:7.4.2.8]
D IT6_09730 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D IT6_04455 secD; protein translocase subunit SecD K12257 secDF; SecD/SecF fusion protein
D IT6_02390 secE; preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D IT6_01530 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D IT6_03205 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D IT6_00470 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D IT6_09125 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D IT6_04460 yajC; preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D IT6_01995 yidC; membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D IT6_04650 twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA
D IT6_02210 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins [BR:mcao02042]
D IT6_07950 HlyC/CorC family transporter K03699 tlyC; magnesium and cobalt exporter, CNNM family
D IT6_06300 hemolysin III family protein K11068 hlyIII; hemolysin III
C 02022 Two-component system [BR:mcao02022]
D IT6_07085 PAS domain-containing protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D IT6_07090 response regulator K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
D IT6_03715 HAMP domain-containing histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
D IT6_05475 response regulator transcription factor K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
D IT6_02865 sensor histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
D IT6_02860 response regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
D IT6_05480 HAMP domain-containing histidine kinase K18351 vanSAc; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
D IT6_03785 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
D IT6_07135 sigma-54-dependent Fis family transcriptional regulator K02481 flgR; two-component system, NtrC family, response regulator
D IT6_07860 sigma-54-dependent Fis family transcriptional regulator K02481 flgR; two-component system, NtrC family, response regulator
D IT6_01105 sigma-54-dependent Fis family transcriptional regulator K02481 flgR; two-component system, NtrC family, response regulator
C 02035 Bacterial motility proteins [BR:mcao02035]
D IT6_08290 OmpA family protein K02557 motB; chemotaxis protein MotB
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:mcao04812]
D IT6_07160 amrB; AmmeMemoRadiSam system protein B K06990 MEMO1; MEMO1 family protein
D IT6_08865 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D IT6_10360 ftsA; cell division protein FtsA K03590 ftsA; cell division protein FtsA
D IT6_08065 ParA family protein K03496 parA; chromosome partitioning protein
D IT6_06550 ParB/RepB/Spo0J family partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
C 04147 Exosome [BR:mcao04147]
D IT6_07705 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D IT6_01515 gap; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D IT6_01520 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D IT6_06065 hypothetical protein K00873 PK; pyruvate kinase [EC:2.7.1.40]
D IT6_06810 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D IT6_05375 groL; chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D IT6_05385 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D IT6_01595 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D IT6_07445 GuaB3 family IMP dehydrogenase-related protein K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D IT6_02400 tuf; elongation factor Tu K02358 tuf; elongation factor Tu
D IT6_00795 histidine triad nucleotide-binding protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D IT6_05985 phenylpyruvate tautomerase K07253 MIF; phenylpyruvate tautomerase [EC:5.3.2.1]
D IT6_03680 selenium-binding protein K17285 SELENBP1; methanethiol oxidase [EC:1.8.3.4]
D IT6_03370 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D IT6_02285 nucleoside monophosphate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D IT6_07345 adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D IT6_06240 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D IT6_09800 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D IT6_03635 hydA; dihydropyrimidinase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D IT6_01560 glgB; 1,4-alpha-glucan branching protein GlgB K00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]
D IT6_08905 glpK; glycerol kinase GlpK K00864 glpK; glycerol kinase [EC:2.7.1.30]
D IT6_00820 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D IT6_01200 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D IT6_01670 4a-hydroxytetrahydrobiopterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D IT6_00570 phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D IT6_01145 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D IT6_09250 M48 family metallopeptidase K06013 STE24; STE24 endopeptidase [EC:3.4.24.84]
D IT6_06755 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_00830 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_01660 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D IT6_04085 electron transfer flavoprotein subunit alpha/FixB family protein K03522 fixB; electron transfer flavoprotein alpha subunit
D IT6_08675 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D IT6_07520 zwf; glucose-6-phosphate dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D IT6_09975 zwf; glucose-6-phosphate dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D IT6_01525 triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D IT6_03720 gpmA; 2,3-diphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
C 02048 Prokaryotic defense system [BR:mcao02048]
D IT6_05805 cas1d; type I-D CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D IT6_02710 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D IT6_05800 cas2; CRISPR-associated endonuclease Cas2 K09951 cas2; CRISPR-associated protein Cas2
D IT6_02715 cas2; CRISPR-associated endonuclease Cas2 K09951 cas2; CRISPR-associated protein Cas2
D IT6_05820 cas3; type I-D CRISPR-associated helicase Cas3' K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
D IT6_05810 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D IT6_05815 cas6; CRISPR-associated endoribonuclease Cas6 K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-]
D IT6_05825 cas5d; type I-D CRISPR-associated protein Cas5/Csc1 K19120 csc1; CRISPR-associated protein Csc1
D IT6_05830 cas7d; type I-D CRISPR-associated protein Cas7/Csc2 K19121 csc2; CRISPR-associated protein Csc2
D IT6_05835 cas10d; type I-D CRISPR-associated protein Cas10d/Csc3 K19122 csc3; CRISPR-associated protein Csc3
D IT6_00045 cas7u; type I-U CRISPR-associated protein Cas7 K19131 csb1; CRISPR-associated protein Csb1
D IT6_02675 cas10; type III-B CRISPR-associated protein Cas10/Cmr2 K19076 cmr2; CRISPR-associated protein Cmr2
D IT6_02680 cmr3; type III-B CRISPR module-associated protein Cmr3 K09127 cmr3; CRISPR-associated protein Cmr3
D IT6_02685 cmr4; type III-B CRISPR module RAMP protein Cmr4 K09000 cmr4; CRISPR-associated protein Cmr4
D IT6_02695 hypothetical protein K19142 cmr6; CRISPR-associated protein Cmr6
D IT6_03135 cmr6; type III-B CRISPR module RAMP protein Cmr6 K19142 cmr6; CRISPR-associated protein Cmr6
D IT6_02525 DEAD/DEAH box helicase family protein K01156 res; type III restriction enzyme [EC:3.1.21.5]
D IT6_01025 site-specific DNA-methyltransferase K07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72]
D IT6_02535 site-specific DNA-methyltransferase K07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72]
D IT6_02540 site-specific DNA-methyltransferase K07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72]
D IT6_02580 restriction endonuclease K07448 mrr; restriction system protein
D IT6_08865 rod shape-determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D IT6_07155 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D IT6_06435 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_00805 aminotransferase class V-fold PLP-dependent enzyme K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_01790 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_02490 aminotransferase class V-fold PLP-dependent enzyme K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D IT6_04145 cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes [BR:mcao01504]
D IT6_03715 HAMP domain-containing histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
D IT6_05475 response regulator transcription factor K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
D IT6_05480 HAMP domain-containing histidine kinase K18351 vanSAc; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
D IT6_04190 heavy metal-responsive transcriptional regulator K19591 cueR; MerR family transcriptional regulator, copper efflux regulator
D IT6_09905 TolC family outer membrane protein K12340 tolC; outer membrane protein
D IT6_10395 TolC family protein K12340 tolC; outer membrane protein
D IT6_05280 efflux transporter outer membrane subunit K18903 oprC; outer membrane protein, multidrug efflux system
D IT6_05460 efflux transporter outer membrane subunit K18903 oprC; outer membrane protein, multidrug efflux system
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:mcao03100]
D IT6_01940 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D IT6_07620 pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase PdxA K22024 pdxA2; 4-phospho-D-threonate 3-dehydrogenase / 4-phospho-D-erythronate 3-dehydrogenase [EC:1.1.1.408 1.1.1.409]
D IT6_00645 2-oxoacid:acceptor oxidoreductase family protein K04090 E1.2.7.8; indolepyruvate ferredoxin oxidoreductase [EC:1.2.7.8]
D IT6_00665 pqqC; pyrroloquinoline-quinone synthase PqqC K06137 pqqC; pyrroloquinoline-quinone synthase [EC:1.3.3.11]
D IT6_04080 FAD-dependent monooxygenase K00313 fixC; electron transfer flavoprotein-quinone oxidoreductase [EC:1.5.5.-]
D IT6_07900 NADPH:quinone reductase K00344 qor; NADPH:quinone reductase [EC:1.6.5.5]
D IT6_08425 NAD(P)H-quinone oxidoreductase K00344 qor; NADPH:quinone reductase [EC:1.6.5.5]
D IT6_08385 NAD(P)H-dependent oxidoreductase K01118 acpD; FMN-dependent NADH-azoreductase [EC:1.7.1.17]
D IT6_01510 bifunctional methionine sulfoxide reductase B/A protein K12267 msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12]
D IT6_04355 cytochrome-c peroxidase K00428 E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5]
D IT6_08395 peroxiredoxin K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D IT6_01740 peroxiredoxin K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D IT6_05180 redoxin domain-containing protein K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25]
D IT6_00250 glutaredoxin K00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1]
D IT6_09625 arsenate reductase ArsC K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D IT6_00655 pqqE; pyrroloquinoline quinone biosynthesis protein PqqE K06139 pqqE; PqqA peptide cyclase [EC:1.21.98.4]
D IT6_03570 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D IT6_03930 hyfB; hydrogenase 4 subunit B K12137 hyfB; hydrogenase-4 component B [EC:1.-.-.-]
D IT6_03920 hydrogenase-4 component E K12140 hyfE; hydrogenase-4 component E [EC:1.-.-.-]
D IT6_03915 hydrogenase 4 subunit F K12141 hyfF; hydrogenase-4 component F [EC:1.-.-.-]
D IT6_07035 arylamine N-acetyltransferase K00675 nhoA; N-hydroxyarylamine O-acetyltransferase [EC:2.3.1.118]
D IT6_09145 lnt; apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269]
D IT6_09740 leucyl/phenylalanyl-tRNA--protein transferase K00684 aat; leucyl/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6]
D IT6_05500 deoxyhypusine synthase family protein K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]
D IT6_04690 lgt; prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]
D IT6_04965 carbohydrate kinase K18478 yihV; sulfofructose kinase [EC:2.7.1.184]
D IT6_01195 glutamine-synthetase adenylyltransferase K00982 glnE; [glutamine synthetase] adenylyltransferase / [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase [EC:2.7.7.42 2.7.7.89]
D IT6_04330 TIGR00159 family protein K18672 dacA; diadenylate cyclase [EC:2.7.7.85]
D IT6_05660 hprK; HPr(Ser) kinase/phosphatase K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-]
D IT6_07430 protein arginine kinase K19405 mcsB; protein arginine kinase [EC:2.7.14.1]
D IT6_07055 O-acetyl-ADP-ribose deacetylase K23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106]
D IT6_08420 acyl-CoA thioesterase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D IT6_00330 sixA; phosphohistidine phosphatase SixA K08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-]
D IT6_08705 HDIG domain-containing protein K07037 pgpH; cyclic-di-AMP phosphodiesterase PgpH [EC:3.1.4.-]
D IT6_05695 TatD family hydrolase K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D IT6_10045 alpha/beta fold hydrolase K01175 ybfF; esterase [EC:3.1.-.-]
D IT6_02040 def; peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D IT6_10255 MoxR family ATPase K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D IT6_10220 SAM-dependent chlorinase/fluorinase K22205 E3.13.2.3; S-adenosyl-L-methionine hydrolase (adenosine-forming) [EC:3.13.2.3]
D IT6_08435 NAD(P)H-hydrate dehydratase K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D IT6_08015 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 E5.2.1.8; peptidylprolyl isomerase [EC:5.2.1.8]
D IT6_05390 UDP-N-acetylmuramate--L-alanine ligase K02558 mpl; UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase [EC:6.3.2.45]
D IT6_06485 RNA ligase K07468 K07468; DNA/RNA ligase [EC:6.5.1.-]
D IT6_03415 mgtA; magnesium-translocating P-type ATPase K01531 mgtA; P-type Mg2+ transporter [EC:7.2.2.14]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
D IT6_01720 fdhD; formate dehydrogenase accessory sulfurtransferase FdhD K02379 fdhD; FdhD protein
D IT6_07645 SUF system NifU family Fe-S cluster assembly protein K04488 iscU; nitrogen fixation protein NifU and related proteins
D IT6_04140 nitrogen fixation protein NifQ K15790 nifQ; nitrogen fixation protein NifQ
D IT6_04205 nifX; nitrogen fixation protein NifX K02596 nifX; nitrogen fixation protein NifX
D IT6_04115 nifT; putative nitrogen fixation protein NifT K02593 nifT; nitrogen fixation protein NifT
D IT6_04150 nitrogen fixation protein NifZ K02597 nifZ; nitrogen fixation protein NifZ
D IT6_04175 nifB; nitrogenase cofactor biosynthesis protein NifB K02585 nifB; nitrogen fixation protein NifB
D IT6_04210 nifN; nitrogenase iron-molybdenum cofactor biosynthesis protein NifN K02592 nifN; nitrogenase molybdenum-iron protein NifN
D IT6_04215 nifE; nitrogenase iron-molybdenum cofactor biosynthesis protein NifE K02587 nifE; nitrogenase molybdenum-cofactor synthesis protein NifE
D IT6_04090 electron transfer flavoprotein subunit beta/FixA family protein K03521 fixA; electron transfer flavoprotein beta subunit
D IT6_04075 ferredoxin family protein K03855 fixX; ferredoxin like protein
D IT6_04095 nitrogenase-stabilizing/protective protein NifW K02595 nifW; nitrogenase-stabilizing/protective protein
D IT6_06620 dodecin domain-containing protein K09165 K09165; dodecin
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
D IT6_05130 YggS family pyridoxal phosphate-dependent enzyme K06997 yggS; PLP dependent protein
C 99986 Glycan metabolism
D IT6_05355 flippase-like domain-containing protein K07027 K07027; glycosyltransferase 2 family protein
D IT6_10215 flippase-like domain-containing protein K07027 K07027; glycosyltransferase 2 family protein
C 99987 Cofactor metabolism
D IT6_01770 mobB; molybdopterin-guanine dinucleotide biosynthesis protein B K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein
C 99988 Secondary metabolism
C 99999 Others
D IT6_04425 DoxX family protein K15977 K15977; putative oxidoreductase
D IT6_06540 bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase K09181 yfiQ; acetyltransferase
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
C 99974 Translation
C 99975 Protein processing
D IT6_03445 clpS; ATP-dependent Clp protease adapter ClpS K06891 clpS; ATP-dependent Clp protease adaptor protein ClpS
D IT6_07240 UvrB/UvrC motif-containing protein K19411 mcsA; protein arginine kinase activator
D IT6_01480 tig; trigger factor K03545 tig; trigger factor
D IT6_01150 smpB; SsrA-binding protein SmpB K03664 smpB; SsrA-binding protein
D IT6_08545 HypC/HybG/HupF family hydrogenase formation chaperone K04653 hypC; hydrogenase expression/formation protein HypC
D IT6_08550 hypD; hydrogenase formation protein HypD K04654 hypD; hydrogenase expression/formation protein HypD
D IT6_08555 hypE; hydrogenase expression/formation protein HypE K04655 hypE; hydrogenase expression/formation protein HypE
D IT6_08540 hypF; carbamoyltransferase HypF K04656 hypF; hydrogenase maturation protein HypF
D IT6_06845 serine protease K07403 nfeD; membrane-bound serine protease (ClpP class)
C 99976 Replication and repair
D IT6_10210 rmuC; DNA recombination protein RmuC K09760 rmuC; DNA recombination protein RmuC
D IT6_00495 YraN family protein K07460 yraN; putative endonuclease
D IT6_02485 tyrosine-type recombinase/integrase K07357 fimB; type 1 fimbriae regulatory protein FimB
D IT6_06355 replication-associated recombination protein A K07478 ycaJ; putative ATPase
D IT6_05105 tnpA; IS200/IS605 family transposase K07491 rayT; REP-associated tyrosine transposase
D IT6_06130 tnpA; IS200/IS605 family transposase K07491 rayT; REP-associated tyrosine transposase
D IT6_09820 tnpA; IS200/IS605 family transposase K07491 rayT; REP-associated tyrosine transposase
D IT6_10285 tnpA; IS200/IS605 family transposase K07491 rayT; REP-associated tyrosine transposase
D IT6_01380 tnpA; IS200/IS605 family transposase K07491 rayT; REP-associated tyrosine transposase
D IT6_02755 tnpA; IS200/IS605 family transposase K07491 rayT; REP-associated tyrosine transposase
D IT6_04435 tnpA; IS200/IS605 family transposase K07491 rayT; REP-associated tyrosine transposase
D IT6_06255 transposase K07496 K07496; putative transposase
D IT6_07560 transposase K07496 K07496; putative transposase
D IT6_08980 transposase K07496 K07496; putative transposase
D IT6_09810 transposase K07496 K07496; putative transposase
D IT6_09885 transposase K07496 K07496; putative transposase
D IT6_01045 transposase K07496 K07496; putative transposase
D IT6_01390 transposase K07496 K07496; putative transposase
D IT6_02725 transposase K07496 K07496; putative transposase
D IT6_03340 transposase K07496 K07496; putative transposase
D IT6_03950 transposase K07496 K07496; putative transposase
D IT6_04430 transposase K07496 K07496; putative transposase
C 99979 Viral proteins
C 99998 Others
D IT6_09070 YbaB/EbfC family nucleoid-associated protein K09747 ebfC; nucleoid-associated protein EbfC
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D IT6_08520 amino acid permease K03294 TC.APA; basic amino acid/polyamine antiporter, APA family
D IT6_09840 amino acid permease K03294 TC.APA; basic amino acid/polyamine antiporter, APA family
D IT6_05200 sodium:solute symporter K03307 TC.SSS; solute:Na+ symporter, SSS family
D IT6_07980 bile acid:sodium symporter K03453 TC.BASS; bile acid:Na+ symporter, BASS family
C 99978 Cell growth
C 99993 Cell motility
C 99995 Signaling proteins
D IT6_10225 typA; translational GTPase TypA K06207 typA; GTP-binding protein
D IT6_08700 PhoH family protein K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins
C 99992 Structural proteins
D IT6_02900 OmpH family outer membrane protein K06142 hlpA; outer membrane protein
D IT6_05715 outer membrane beta-barrel protein K07275 ompW; outer membrane protein
D IT6_04820 Slp family lipoprotein K07285 slp; outer membrane lipoprotein
D IT6_04825 Slp family lipoprotein K07285 slp; outer membrane lipoprotein
D IT6_08620 Slp family lipoprotein K07285 slp; outer membrane lipoprotein
D IT6_00345 Slp family lipoprotein K07285 slp; outer membrane lipoprotein
D IT6_01815 Slp family lipoprotein K07285 slp; outer membrane lipoprotein
D IT6_02775 Slp family lipoprotein K07285 slp; outer membrane lipoprotein
D IT6_08180 helix-turn-helix domain-containing protein K15539 rodZ; cytoskeleton protein RodZ
C 99994 Others
D IT6_05330 phoU; phosphate signaling complex protein PhoU K02039 phoU; phosphate transport system protein
D IT6_09285 glucan biosynthesis protein K03670 mdoG; periplasmic glucans biosynthesis protein
D IT6_09290 glucan biosynthesis protein K03670 mdoG; periplasmic glucans biosynthesis protein
D IT6_01500 divalent-cation tolerance protein CutA K03926 cutA; periplasmic divalent cation tolerance protein
D IT6_09670 ApaG domain K06195 apaG; ApaG protein
D IT6_04570 nitrous oxide reductase family maturation protein NosD K07218 nosD; nitrous oxidase accessory protein
D IT6_04575 nitrous oxide reductase accessory protein NosL K19342 nosL; copper chaperone NosL
B
B 09194 Poorly characterized
C 99996 General function prediction only
D IT6_00670 pyrroloquinoline quinone biosynthesis protein PqqB K06136 pqqB; pyrroloquinoline quinone biosynthesis protein B
D IT6_00660 pqqD; pyrroloquinoline quinone biosynthesis peptide chaperone PqqD K06138 pqqD; pyrroloquinoline quinone biosynthesis protein D
D IT6_00740 globin K06886 glbN; hemoglobin
D IT6_07960 HAD hydrolase-like protein K07025 K07025; putative hydrolase of the HAD superfamily
D IT6_01695 HAD family phosphatase K07025 K07025; putative hydrolase of the HAD superfamily
D IT6_08030 iron-sulfur cluster assembly accessory protein K15724 erpA; iron-sulfur cluster insertion protein
D IT6_04125 erpA; iron-sulfur cluster insertion protein ErpA K15724 erpA; iron-sulfur cluster insertion protein
D IT6_06405 sufB; Fe-S cluster assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB
D IT6_06410 SufD family Fe-S cluster assembly protein K09015 sufD; Fe-S cluster assembly protein SufD
D IT6_06875 YihY/virulence factor BrkB family protein K07058 K07058; membrane protein
D IT6_08455 phosphoribosyltransferase K07100 K07100; putative phosphoribosyl transferase
D IT6_01125 SufE family protein K02426 sufE; cysteine desulfuration protein SufE
D IT6_08365 VTT domain-containing protein K03975 dedA; membrane-associated protein
D IT6_00140 DUF202 domain-containing protein K00389 yidH; putative membrane protein
D IT6_08785 DUF420 domain-containing protein K08976 K08976; putative membrane protein
D IT6_00320 hypothetical protein K03618 hyaF; hydrogenase-1 operon protein HyaF
C 99997 Function unknown
D IT6_07070 thioredoxin domain-containing protein K06888 K06888; uncharacterized protein
D IT6_06820 alpha/beta hydrolase K06889 K06889; uncharacterized protein
D IT6_01760 alpha/beta fold hydrolase K06889 K06889; uncharacterized protein
D IT6_06175 ATP/GTP-binding protein K06945 K06945; uncharacterized protein
D IT6_08890 NYN domain-containing protein K06962 K06962; uncharacterized protein
D IT6_04720 polysaccharide deacetylase family protein K06986 K06986; uncharacterized protein
D IT6_02795 cupin domain-containing protein K06995 K06995; uncharacterized protein
D IT6_00730 MMPL family transporter K07003 K07003; uncharacterized protein
D IT6_03765 AAA family ATPase K07028 K07028; uncharacterized protein
D IT6_07580 sulfite exporter TauE/SafE family protein K07090 K07090; uncharacterized protein
D IT6_03655 sulfite exporter TauE/SafE family protein K07090 K07090; uncharacterized protein
D IT6_04420 metallophosphoesterase K07098 K07098; uncharacterized protein
D IT6_06815 SDR family oxidoreductase K07124 K07124; uncharacterized protein
D IT6_06180 roadblock/LC7 domain-containing protein K07131 K07131; uncharacterized protein
D IT6_07725 ATP-binding protein K07133 K07133; uncharacterized protein
D IT6_01160 DNA-binding protein K07164 K07164; uncharacterized protein
D IT6_02000 yidD; membrane protein insertion efficiency factor YidD K08998 K08998; uncharacterized protein
D IT6_05115 bifunctional nuclease family protein K08999 K08999; uncharacterized protein
D IT6_10135 DUF763 domain-containing protein K09003 K09003; uncharacterized protein
D IT6_08200 DUF192 domain-containing protein K09005 K09005; uncharacterized protein
D IT6_05440 GatB/YqeY domain-containing protein K09117 K09117; uncharacterized protein
D IT6_09265 Mut7-C ubiquitin/RNAse domain-containing protein K09122 K09122; uncharacterized protein
D IT6_00400 DUF167 domain-containing protein K09131 K09131; uncharacterized protein
D IT6_07125 DMT family protein K09922 K09922; uncharacterized protein
D IT6_08090 DUF2062 domain-containing protein K09928 K09928; uncharacterized protein
D IT6_00240 DUF692 domain-containing protein K09930 K09930; uncharacterized protein
D IT6_09645 DUF4912 domain-containing protein K09942 K09942; uncharacterized protein
D IT6_06285 YdbL family protein K09978 K09978; uncharacterized protein
D IT6_10085 YdbL family protein K09978 K09978; uncharacterized protein
!
#
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: June 22, 2024