+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Mycobacterium canettii CIPT 140010059</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
C    MCAN_28411 conserved hypothetical protein	K15342 cas1; CRISP-associated protein Cas1 
C    MCAN_28401 conserved hypothetical protein	K09951 cas2; CRISPR-associated protein Cas2 
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
D      MCAN_28471 conserved hypothetical protein	K07016 csm1; CRISPR-associated protein Csm1 
C    Subtype III-A factors
D      MCAN_28461 putative uncharacterized protein	K19138 csm2; CRISPR-associated protein Csm2 
D      MCAN_28451 conserved hypothetical protein	K09002 csm3; CRISPR-associated protein Csm3 
D      MCAN_28441 hypothetical protein	K19139 csm4; CRISPR-associated protein Csm4 
D      MCAN_28431 hypothetical protein	K19140 csm5; CRISPR-associated protein Csm5 
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
C    MCAN_27831 hsdM; putative type I restriction/modification system DNA methylase HSDM (M protein) (DNA methyltransferase)	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] 
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
B  Type III R-M system
B  Type IV R-M system
C    MCAN_25681 mrr; putative restriction system protein MRR	K07448 mrr; restriction system protein 
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
D      MCAN_04551 conserved hypothetical protein	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      MCAN_19591 conserved hypothetical protein	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      MCAN_06581 conserved hypothetical protein	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      MCAN_15131 conserved hypothetical protein	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      MCAN_20111 conserved hypothetical protein	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      MCAN_28281 conserved hypothetical protein	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      MCAN_22981 hypothetical protein	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      MCAN_06591 conserved hypothetical protein	K26982 mazE2; antitoxin MazE2 
D      MCAN_11131 conserved hypothetical protein	K26983 mazE3; antitoxin MazE3 
D      MCAN_15121 hypothetical protein	K26984 mazE4; antitoxin MazE4 
D      MCAN_19601 conserved hypothetical protein	K26985 mazE5; antitoxin MazE5 
D      MCAN_20861 conserved hypothetical protein	K26987 mazE7; antitoxin MazE7 
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
D      MCAN_28881 conserved hypothetical protein	K06218 relE; mRNA interferase RelE/StbE 
D      MCAN_12601 conserved hypothetical protein	K06218 relE; mRNA interferase RelE/StbE 
C    YafQ-dinJ
C    YoeB-YefM
D      MCAN_33841 conserved hypothetical protein	K19158 yoeB; toxin YoeB [EC:3.1.-.-] 
D      MCAN_33831 conserved hypothetical protein	K19159 yefM; antitoxin YefM 
D      MCAN_28871 conserved hypothetical protein	K19159 yefM; antitoxin YefM 
D      MCAN_12611 conserved hypothetical protein	K19159 yefM; antitoxin YefM 
C    HipA-HipB
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
D      MCAN_19751 conserved hypothetical protein	K19092 parE1_3_4; toxin ParE1/3/4 
D      MCAN_21661 hypothetical protein	K19093 parE2; toxin ParE2 
D      MCAN_19761 conserved hypothetical protein	K07746 parD1_3_4; antitoxin ParD1/3/4 
C    Doc-Phd
C    HigB-HigA
C    MqsR-MqsA
C    VapC-VapB
D      MCAN_06101 conserved hypothetical protein	K19686 vapC; ribonuclease VapC [EC:3.1.-.-] 
D      MCAN_27861 conserved hypothetical protein	K19686 vapC; ribonuclease VapC [EC:3.1.-.-] 
D      MCAN_20021 conserved hypothetical protein	K19686 vapC; ribonuclease VapC [EC:3.1.-.-] 
D      MCAN_17551 conserved hypothetical protein	K19686 vapC; ribonuclease VapC [EC:3.1.-.-] 
D      MCAN_17541 conserved hypothetical protein	K19687 vapB; antitoxin VapB 
D      MCAN_06091 conserved hypothetical protein	K19687 vapB; antitoxin VapB 
D      MCAN_27871 conserved hypothetical protein	K19687 vapB; antitoxin VapB 
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
D      MCAN_19681 conserved hypothetical protein	K21495 fitA; antitoxin FitA 
C    BC_0920-BC_0921
C    Type II TA system related factors
D      MCAN_21741 ftsZ; cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      MCAN_30141 gltS; putative glutamyl-tRNA synthetase GLTS (glutamate--tRNA ligase) (glutamyl-tRNA synthase) (GLURS)	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    MCAN_30501 iscS; putative cysteine desulfurase ISCS (NIFS protein homolog) (nitrogenase metalloclusters biosynthesis protein NIFS)	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023