+F Repair protein KO #

  DNA Repair and Recombination Proteins - Mycobacterium canettii CIPT 140010059

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D MCAN_13321 ogt; putative methylated-DNA--protein-cysteine methyltransferase OGT (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] C BER (base exicision repair) D DNA glycosylases E MCAN_29981 ung; putative uracil-DNA glycosylase UNG (UDG) K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E MCAN_16971 mpg; putative 3-methyladenine DNA glycosylase MPG K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E MCAN_36021 mutY; putative adenine glycosylase MUTY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E MCAN_36941 nth; putative endonuclease III NTH (DNA-(apurinic or apyrimidinic site)lyase) (AP lyase) (AP endonuclease class I) (endodeoxyribonuclease (apurinic or apyrimidinic)) (deoxyribonuclease (apurinic or apyrimidinic)) K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex E DNA polymerase epsilon complex D Short Patch-BER factors D Other BER factors C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex E Cul4-CSA complex E Other TCR factor D TFIIH complex E MCAN_08631 ercc3; putative DNA helicase ERCC3 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] D RPA (replication factor A) D Other NER factors C MMR (mismatch excision repair) D Mismatch and loop recognition factors D MutL homologs D DNA polymerase delta complex D RPA (replication factor A) D RFC (replication factor C) D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex D BRCA complex D RecA family proteins D Rad52 family proteins D Rad54 family proteins D RecQ family DNA helicases D Bloom's syndrome complex (BTR) D RPA (replication factor A) D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex D Other HR factors C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) D FANCD2-I complex D Downstream FA components D Other FA pathway factors C Other DSBR factors D Protein phosphatase 6 D Ubiquitin ligases D Others B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group C Other TLS factors B Check point factors C Rad9-Hus1-Rad1 complex C HRAD17(Rad24)-RFC complex C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex C Other check point factors B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex C Modulation of nucleotide pools D MCAN_11711 mutT2; putative mutator protein MUTT (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-DGTPASE) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MCAN_04111 mutT3; putative mutator protein MUTT3 (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-DGTPASE) (DGTP pyrophosphohydrolase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MCAN_16011 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MCAN_27231 dut; putative deoxyuridine 5'-triphosphate nucleotidohydrolase DUT (DUTPASE) (DUTP pyrophosphatase) (deoxyuridine 5'-triphosphatase) (DUTP diphosphatase) (deoxyuridine-triphosphatase) K01520 dut; dUTP diphosphatase [EC:3.6.1.23] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D MCAN_13321 ogt; putative methylated-DNA--protein-cysteine methyltransferase OGT (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] C BER (base exicision repair) D DNA glycosylases E MCAN_29981 ung; putative uracil-DNA glycosylase UNG (UDG) K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E MCAN_12731 conserved hypothetical protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] E MCAN_13331 alkA; putative ADA regulatory protein ALKA (regulatory protein of adaptative response) (methylated-DNA--protein-cysteine methyltransferase) (O-6-methylguanine-DNA alkyltransferase) (O-6-methylguanine-DNA methyltransferase) (3-methyladenine DNA glycosylase II) K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21] E MCAN_16971 mpg; putative 3-methyladenine DNA glycosylase MPG K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E MCAN_36021 mutY; putative adenine glycosylase MUTY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E MCAN_12241 tagA; putative DNA-3-methyladenine glycosylase I TAGA (TAG I) (3-methyladenine-DNA glycosylase I, constitutive) (DNA-3-methyladenine glycosidase I) K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] E MCAN_09471 dna glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E MCAN_29461 fpg; putative formamidopyrimidine-DNA glycosylase FPG (FAPY-DNA glycosylase) K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E MCAN_25031 putative DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E MCAN_33201 nei; putative endonuclease VIII NEI K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E MCAN_36941 nth; putative endonuclease III NTH (DNA-(apurinic or apyrimidinic site)lyase) (AP lyase) (AP endonuclease class I) (endodeoxyribonuclease (apurinic or apyrimidinic)) (deoxyribonuclease (apurinic or apyrimidinic)) K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E MCAN_04251 xthA; putative exodeoxyribonuclease III protein XTHA (exonuclease III) (EXO III) (AP endonuclease VI) K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] E MCAN_06701 end; putative endonuclease IV END (endodeoxyribonuclease IV) (apurinase) K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D RecJ D DNA ligase E MCAN_30371 ligA; putative DNA ligase [NAD dependent] LIGA (polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D DNA polymerase I E MCAN_16371 polA; putative DNA polymerase I POLA K02335 polA; DNA polymerase I [EC:2.7.7.7] C NER (nucleotide excision repair) D GGR (global genome repair) factors E MCAN_16461 uvrA; putative excinuclease ABC (subunit A-DNA-binding ATPase) UVRA K03701 uvrA; excinuclease ABC subunit A E MCAN_16411 uvrB; putative excinuclease ABC (subunit B-helicase) UVRB K03702 uvrB; excinuclease ABC subunit B E MCAN_14361 uvrC; putative excinuclease ABC (subunit C-nuclease) UVRC K03703 uvrC; excinuclease ABC subunit C E MCAN_09531 uvrD1; putative ATP-dependent DNA helicase II UVRD1 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E MCAN_32131 uvrD2; putative ATP-dependent DNA helicase II UVRD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E MCAN_32171 putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E MCAN_16371 polA; putative DNA polymerase I POLA K02335 polA; DNA polymerase I [EC:2.7.7.7] E MCAN_30371 ligA; putative DNA ligase [NAD dependent] LIGA (polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) F MCAN_06671 rpoB; DNA-directed RNA polymerase (beta chain) RPOB (transcriptase beta chain) (RNA polymerase beta subunit) K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] F MCAN_06681 rpoC; DNA-directed RNA polymerase (beta' chain) RPOC (transcriptase beta' chain) (RNA polymerase beta' subunit) K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] F MCAN_34741 rpoA; putative DNA-directed RNA polymerase (alpha chain) RPOA (transcriptase alpha chain) (RNA polymerase alpha subunit) (DNA-directed RNA nucleotidyltransferase) K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] F MCAN_14061 rpoZ; putative DNA-directed RNA polymerase (omega chain) RPOZ (transcriptase omega chain) (RNA polymerase omega subunit) K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] E TRCF (transcription-repair coupling factor) F MCAN_10251 mfd; putative transcription-repair coupling factor MFD (TRCF) K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] C MMR (mismatch excision repair) D Mismatch and loop recognition factors D Molecular matchmaker D Strand discrimination factor D DNA exonucleases E MCAN_11181 xseA; putative exodeoxyribonuclease VII (large subunit) XSEA (exonuclease VII large subunit) K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E MCAN_11171 xseB; putative exodeoxyribonuclease VII (small subunit) XSEA (exonuclease VII small subunit) K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D DNA polymerase III holoenzyme E MCAN_15701 dnaE1; putative DNA polymerase III (alpha chain) DNAE1 (DNA nucleotidyltransferase) K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E MCAN_00011 dnaN; DNA polymerase III (beta chain) DNAN (DNA nucleotidyltransferase) K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E MCAN_24471 conserved hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E MCAN_36641 putative DNA polymerase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E MCAN_37331 dnaQ; putative DNA polymerase III (epsilon subunit) DNAQ K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E MCAN_22131 conserved hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E MCAN_37431 dnaZX; DNA polymerase III (subunit gamma/TAU) DNAZ/X K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D DNA ligase E MCAN_30371 ligA; putative DNA ligase [NAD dependent] LIGA (polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Other MMR factors E MCAN_09531 uvrD1; putative ATP-dependent DNA helicase II UVRD1 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E MCAN_32131 uvrD2; putative ATP-dependent DNA helicase II UVRD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E MCAN_32171 putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E MCAN_00531 ssb; putative single-strand binding protein SSB (helix-destabilizing protein) K03111 ssb; single-strand DNA-binding protein E MCAN_25171 conserved hypothetical protein K03111 ssb; single-strand DNA-binding protein B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins E MCAN_06271 recB; putative exonuclease V (beta chain) RECB (exodeoxyribonuclease V beta chain)(exodeoxyribonuclease V polypeptide) (chi-specific endonuclease) K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5] E MCAN_06281 recC; putative exonuclease V (gamma chain) RECC (exodeoxyribonuclease V gamma chain)(exodeoxyribonuclease V polypeptide) K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5] E MCAN_06261 recD; putative exonuclease V (alpha chain) RECD (exodeoxyribonuclease V alpha chain) (exodeoxyribonuclease V polypeptide) K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] E MCAN_27631 recA; RECA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RECA intein)] K03553 recA; recombination protein RecA E MCAN_26351 ruvA; putative Holliday junction DNA helicase RUVA K03550 ruvA; holliday junction DNA helicase RuvA E MCAN_26341 ruvB; putative Holliday junction DNA helicase RUVB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E MCAN_26361 ruvC; putative crossover junction endodeoxyribonuclease RUVC (Holliday junction nuclease) (holliday junction resolvase) K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] E MCAN_14181 priA; putative primosomal protein N' PRIA (replication factor Y) K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D RecFOR pathway proteins E MCAN_27631 recA; RECA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RECA intein)] K03553 recA; recombination protein RecA E MCAN_35981 radA; DNA repair protein RADA (DNA repair protein SMS) K04485 radA; DNA repair protein RadA/Sms E MCAN_00021 recF; DNA replication and repair protein RECF (single-strand DNA binding protein) K03629 recF; DNA replication and repair protein RecF E MCAN_29961 recG; putative ATP-dependent DNA helicase RECG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E MCAN_23941 conserved hypothetical protein K03584 recO; DNA repair protein RecO (recombination protein O) E MCAN_37371 recR; putative recombination protein RECR K06187 recR; recombination protein RecR E MCAN_17051 recN; putative DNA repair protein RECN (recombination protein N) K03631 recN; DNA repair protein RecN (Recombination protein N) E MCAN_26351 ruvA; putative Holliday junction DNA helicase RUVA K03550 ruvA; holliday junction DNA helicase RuvA E MCAN_26341 ruvB; putative Holliday junction DNA helicase RUVB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E MCAN_26361 ruvC; putative crossover junction endodeoxyribonuclease RUVC (Holliday junction nuclease) (holliday junction resolvase) K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D AddAB pathway proteins D Other HR factor E MCAN_28411 conserved hypothetical protein K15342 cas1; CRISP-associated protein Cas1 D Archaeal homologous recombinant proteins E MCAN_25491 conserved hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex E MCAN_09371 conserved hypothetical protein K10979 ku; DNA end-binding protein Ku E MCAN_09381 putative ATP dependent DNA ligase (ATP dependent polydeoxyribonucleotide synthase) (thermostable DNA ligase) (ATP dependent polynucleotide ligase) (sealase) (DNA repair enzyme) (DNA joinase) K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F MCAN_00051 gyrA; DNA gyrase (subunit A) GYRA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F MCAN_00041 gyrB; DNA gyrase (subunit B) GYRB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F MCAN_36661 topA; DNA topoisomerase I TOPA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) (nicking-closing enzyme) (TOPO I) K03168 topA; DNA topoisomerase I [EC:5.6.2.1] E Supressor F MCAN_30081 hupB; putative DNA-binding protein HU homolog HUPB (histone-like protein) (HLP) (21-KDA laminin-2-binding protein) K03530 hupB; DNA-binding protein HU-beta D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway F MCAN_23941 conserved hypothetical protein K03584 recO; DNA repair protein RecO (recombination protein O) F MCAN_37371 recR; putative recombination protein RECR K06187 recR; recombination protein RecR F MCAN_30371 ligA; putative DNA ligase [NAD dependent] LIGA (polydeoxyribonucleotide synthase [NAD+]) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E Facilitator E Supressor F MCAN_16461 uvrA; putative excinuclease ABC (subunit A-DNA-binding ATPase) UVRA K03701 uvrA; excinuclease ABC subunit A F MCAN_16411 uvrB; putative excinuclease ABC (subunit B-helicase) UVRB K03702 uvrB; excinuclease ABC subunit B B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D MCAN_15601 dinX; putative DNA polymerase IV DINX (POL IV 1) (DNA nucleotidyltransferase (DNA-directed)) K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D MCAN_30811 dinP; putative DNA-damage-inducible protein P DINP (DNA polymerase V) (POL IV 2) (DNA nucleotidyltransferase (DNA-directed)) K02346 dinB; DNA polymerase IV [EC:2.7.7.7] C Other SOS response factors D MCAN_27631 recA; RECA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RECA intein)] K03553 recA; recombination protein RecA D MCAN_27461 lexA; repressor LEXA K01356 lexA; repressor LexA [EC:3.4.21.88] D MCAN_17051 recN; putative DNA repair protein RECN (recombination protein N) K03631 recN; DNA repair protein RecN (Recombination protein N) D MCAN_34171 conserved hypothetical protein K14161 imuB; protein ImuB D MCAN_00531 ssb; putative single-strand binding protein SSB (helix-destabilizing protein) K03111 ssb; single-strand DNA-binding protein D MCAN_25171 conserved hypothetical protein K03111 ssb; single-strand DNA-binding protein D MCAN_27621 recX; regulatorY protein RECX K03565 recX; regulatory protein B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases D MCAN_13471 dinG; putative ATP-dependent helicase DING K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D MCAN_33191 lhr; putative ATP-dependent helicase LHR (large helicase-related protein) K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] C Modulation of nucleotide pools D MCAN_11711 mutT2; putative mutator protein MUTT (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-DGTPASE) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MCAN_04111 mutT3; putative mutator protein MUTT3 (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-DGTPASE) (DGTP pyrophosphohydrolase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MCAN_16011 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MCAN_30071 mutT1; putative hydrolase MUTT1 K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69] D MCAN_17091 conserved hypothetical protein K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58] D MCAN_27231 dut; putative deoxyuridine 5'-triphosphate nucleotidohydrolase DUT (DUTPASE) (DUTP pyrophosphatase) (deoxyuridine 5'-triphosphatase) (DUTP diphosphatase) (deoxyuridine-triphosphatase) K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D MCAN_05731 nrdZ; putative ribonucleoside-diphosphate reductase (large subunit) NRDZ (ribonucleotide reductase) K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D MCAN_30761 nrdE; ribonucleoside-diphosphate reductase (alpha chain) NRDE (ribonucleotide reductase small subunit) (R1F protein) K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D MCAN_30731 nrdF2; ribonucleoside-diphosphate reductase (beta chain) NRDF2 (ribonucleotide reductase small subunit) (R2F protein) K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D MCAN_02391 nrdB; putative ribonucleoside-diphosphate reductase (beta chain) NRDB (ribonucleotide reductase small chain) K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D MCAN_20011 nrdF1; ribonucleoside-diphosphate reductase (beta chain) NRDF1 (ribonucleotide reductase small subunit) (R2F protein) K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C Others D MCAN_28591 conserved hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024