+F Repair protein KO
#
DNA Repair and Recombination Proteins - Methyloprofundus sp. INp10_methR40d
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D methR_P3060 hypothetical protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E methR_P1501 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E methR_P3771 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E methR_P0029 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
E methR_P1433 DNA excision repair protein ERCC-4 K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D methR_P3045 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D methR_P0482 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D methR_P0590 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D methR_P3846 dUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D methR_P3060 hypothetical protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E methR_P1501 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E methR_P1676 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E methR_P3771 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E methR_P1673 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E methR_P0927 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E methR_P0029 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E methR_P0096 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E methR_P2073 single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E methR_P2445 DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E methR_P0121 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E methR_P2011 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E methR_P1511 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E methR_P2241 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E methR_P2587 DNA helicase II/ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E methR_P0121 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E methR_P2445 DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F methR_P3493 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F methR_P3492 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F methR_P3461 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F methR_P2245 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F methR_P3234 transcription-repair coupling factor, superfamily II helicase K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E methR_P1939 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E methR_P0488 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E methR_P3254 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E methR_P1041 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E methR_P2218 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E methR_P2870 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E methR_P1572 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E methR_P3691 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E methR_P2437 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E methR_P3330 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E methR_P2502 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E methR_P0492 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E methR_P1296 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E methR_P2445 DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E methR_P2587 DNA helicase II/ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E methR_P1549 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E methR_P0695 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E methR_P3948 exodeoxyribonuclease V beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E methR_P3632 exodeoxyribonuclease V gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E methR_P3657 exodeoxyribonuclease V alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E methR_P2933 recombination protein RecA K03553 recA; recombination protein RecA
E methR_P1820 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E methR_P1819 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E methR_P1821 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E methR_P3323 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E methR_P1041 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E methR_P2414 DNA repair protein SbcC/Rad50 K03546 sbcC; DNA repair protein SbcC/Rad50
E methR_P3711 DNA repair protein SbcC/Rad50 K03546 sbcC; DNA repair protein SbcC/Rad50
E methR_P3712 DNA repair protein SbcD/Mre11 K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E methR_P2933 recombination protein RecA K03553 recA; recombination protein RecA
E methR_P2059 DNA repair protein RadA/Sms K04485 radA; DNA repair protein RadA/Sms
E methR_P3692 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E methR_P0911 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E methR_P2248 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E methR_P2073 single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E methR_P1088 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E methR_P1298 recombination protein RecR K06187 recR; recombination protein RecR
E methR_P2521 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E methR_P0992 recombination associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E methR_P1820 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E methR_P1819 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E methR_P1821 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E methR_P3911 CRISP-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E methR_P2414 DNA repair protein SbcC/Rad50 K03546 sbcC; DNA repair protein SbcC/Rad50
E methR_P3711 DNA repair protein SbcC/Rad50 K03546 sbcC; DNA repair protein SbcC/Rad50
E methR_P3712 DNA repair protein SbcD/Mre11 K03547 sbcD; DNA repair protein SbcD/Mre11
E methR_P3210 hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F methR_P1936 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F methR_P3695 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F methR_P3071 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F methR_P3262 DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F methR_P2073 single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F methR_P1088 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F methR_P1298 recombination protein RecR K06187 recR; recombination protein RecR
F methR_P2445 DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F methR_P0152 Fis family transcriptional regulator, factor for inversion stimulation protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F methR_P0216 integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F methR_P1928 integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F methR_P1041 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F methR_P1533 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F methR_P2011 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F methR_P1511 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F methR_P1060 DNA-binding protein H-NS K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D methR_P0823 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D methR_P2933 recombination protein RecA K03553 recA; recombination protein RecA
D methR_P1309 repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D methR_P2521 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D methR_P1549 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D methR_P0695 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D methR_P2932 regulatory protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D methR_P3796 ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D methR_P0182 DNA helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4]
D methR_P0360 ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D methR_P3045 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D methR_P0482 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D methR_P0590 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D methR_P3846 dUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D methR_P3754 ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024