+C Two-component system KO
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Two-Component System - Pulveribacter suum
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C C7H73_07720 phoR; phosphate regulon sensor histidine kinase PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C C7H73_07715 phoB; phosphate regulon transcriptional regulatory protein PhoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
C C7H73_09715 two-component sensor histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C C7H73_09710 two-component system response regulator OmpR K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
B RstB-RstA
C C7H73_02430 two-component sensor histidine kinase K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
C C7H73_11120 two-component sensor histidine kinase K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C C7H73_11115 DNA-binding response regulator K07666 qseB; two-component system, OmpR family, response regulator QseB
B KdpD-KdpE (potassium transport)
C C7H73_11425 histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C C7H73_11420 DNA-binding response regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
C C7H73_00740 histidine kinase K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
C C7H73_00735 DNA-binding response regulator K07774 tctD; two-component system, OmpR family, response regulator TctD
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C C7H73_08140 two-component sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C C7H73_04610 two-component sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C C7H73_00910 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C C7H73_08145 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C C7H73_04605 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C C7H73_01260 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
C C7H73_00325 histidine kinase K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3]
C C7H73_00320 DNA-binding response regulator K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
C C7H73_04865 DNA-binding response regulator K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
C C7H73_03775 DNA-binding response regulator K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
C C7H73_05780 sensor histidine kinase K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]
C C7H73_05750 DNA-binding response regulator K08083 algR; two-component system, LytTR family, response regulator AlgR
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
C C7H73_06720 PAS domain-containing sensor histidine kinase K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C C7H73_06725 ntrC; nitrogen regulation protein NR(I) K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
C C7H73_03275 PAS domain-containing sensor histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
C C7H73_03280 two-component system response regulator K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
B HydH-HydG (metal tolerance)
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
C C7H73_04370 PAS domain-containing sensor histidine kinase K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
C C7H73_04365 sigma-54-dependent Fis family transcriptional regulator K02667 pilR; two-component system, NtrC family, response regulator PilR
B GlrK-GlrR (amino sugar metabolism)
C C7H73_04415 two-component sensor histidine kinase K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
C C7H73_04405 two-component system response regulator GlrR K07715 glrR; two-component system, NtrC family, response regulator GlrR
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
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ACheA family
B CheA-CheYBV (chemotaxis)
C C7H73_03795 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C C7H73_03665 chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C C7H73_03790 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C C7H73_14645 chemotaxis protein CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C C7H73_03815 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
B ChpA-ChpB/PilGH (chemosensory)
C C7H73_04545 hybrid sensor histidine kinase/response regulator K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator)
C C7H73_04525 two-component system response regulator K02657 pilG; twitching motility two-component system response regulator PilG
C C7H73_04530 two-component system response regulator K02658 pilH; twitching motility two-component system response regulator PilH
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
C C7H73_08060 hybrid sensor histidine kinase/response regulator K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
C C7H73_02810 PAS domain-containing sensor histidine kinase K11711 dctS; two-component system, LuxR family, sensor histidine kinase DctS [EC:2.7.13.3]
C C7H73_12985 hypothetical protein K11711 dctS; two-component system, LuxR family, sensor histidine kinase DctS [EC:2.7.13.3]
C C7H73_02805 DNA-binding response regulator K11712 dctR; two-component system, LuxR family, response regulator DctR
C C7H73_12990 DNA-binding response regulator K11712 dctR; two-component system, LuxR family, response regulator DctR
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C C7H73_07230 histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C C7H73_07225 two-component system response regulator K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
B PdtaS-PdtaR
B NasS-NasT
B Unclassified
C C7H73_05305 histidine kinase K20971 ladS; two-component system, sensor histidine kinase LadS
C C7H73_00875 histidine kinase K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023