+D GENES KO #

  KEGG Orthology (KO) - Candidatus Methanoliparum sp. LAM-1

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A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:melu00010] D MTLP_09890 hypothetical protein K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9] D MTLP_04030 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D MTLP_01120 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D MTLP_04020 triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D MTLP_05710 glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] D MTLP_12060 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D MTLP_09200 phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D MTLP_12590 phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D MTLP_10760 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D MTLP_10450 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D MTLP_04530 porA; Pyruvate synthase subunit A K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D MTLP_04520 porB; Pyruvate synthase subunit B K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D MTLP_04550 porC_2; Pyruvate synthase subunit C K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D MTLP_04540 porC_1; Pyruvate synthase subunit D K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D MTLP_05590 Acetyl-CoA ligase/synthetase I (AMP-forming) subunit A K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D MTLP_04170 Acetyl-CoA synthetase II (AMP-forming) subunit A K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D MTLP_09860 Acetyl-CoA synthetase II (AMP-forming) subunit B K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] D MTLP_07890 CoA-binding protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D MTLP_12410 acyl-CoA synthetase K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D MTLP_13010 hypothetical protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D MTLP_10320 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D MTLP_03990 hypothetical protein K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] C 00020 Citrate cycle (TCA cycle) [PATH:melu00020] D MTLP_12040 isopropylmalate synthase K05942 E2.3.3.3; citrate (Re)-synthase [EC:2.3.3.3] D MTLP_10470 isocitrate/isopropylmalate dehydrogenase K00030 IDH3; isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] D MTLP_04970 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D MTLP_04980 fumarate hydratase K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D MTLP_03990 hypothetical protein K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] D MTLP_04530 porA; Pyruvate synthase subunit A K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D MTLP_04520 porB; Pyruvate synthase subunit B K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D MTLP_04550 porC_2; Pyruvate synthase subunit C K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D MTLP_04540 porC_1; Pyruvate synthase subunit D K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] C 00030 Pentose phosphate pathway [PATH:melu00030] D MTLP_09890 hypothetical protein K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9] D MTLP_05720 ribose-5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] D MTLP_05990 fae_1; 3-hexulose-6-phosphate synthase K13812 fae-hps; bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43] D MTLP_11470 hypothetical protein K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D MTLP_12130 (Fe-S)-cluster assembly protein K13831 hps-phi; 3-hexulose-6-phosphate synthase / 6-phospho-3-hexuloisomerase [EC:4.1.2.43 5.3.1.27] D MTLP_10320 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D MTLP_10660 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D MTLP_04130 hypothetical protein K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5] D MTLP_00050 aldehyde ferredoxin oxidoreductase K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5] D MTLP_00130 aldehyde ferredoxin oxidoreductase K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5] D MTLP_04030 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D MTLP_01120 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] C 00040 Pentose and glucuronate interconversions D MTLP_06590 fructose-bisphosphate aldolase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] C 00051 Fructose and mannose metabolism [PATH:melu00051] D MTLP_10320 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D MTLP_05230 mannose-1-phosphate guanyltransferase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] D MTLP_06590 fructose-bisphosphate aldolase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] D MTLP_04030 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D MTLP_01120 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D MTLP_04020 triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D MTLP_05720 ribose-5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] C 00052 Galactose metabolism D MTLP_10320 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] C 00053 Ascorbate and aldarate metabolism C 00500 Starch and sucrose metabolism [PATH:melu00500] D MTLP_10320 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D MTLP_09890 hypothetical protein K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:melu00520] D MTLP_10320 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D MTLP_09890 hypothetical protein K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9] D MTLP_05230 mannose-1-phosphate guanyltransferase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] C 00620 Pyruvate metabolism [PATH:melu00620] D MTLP_04530 porA; Pyruvate synthase subunit A K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D MTLP_04520 porB; Pyruvate synthase subunit B K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D MTLP_04550 porC_2; Pyruvate synthase subunit C K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D MTLP_04540 porC_1; Pyruvate synthase subunit D K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D MTLP_01170 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D MTLP_05590 Acetyl-CoA ligase/synthetase I (AMP-forming) subunit A K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D MTLP_04170 Acetyl-CoA synthetase II (AMP-forming) subunit A K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D MTLP_09860 Acetyl-CoA synthetase II (AMP-forming) subunit B K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] D MTLP_07890 CoA-binding protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D MTLP_12410 acyl-CoA synthetase K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D MTLP_13010 hypothetical protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D MTLP_04830 hypothetical protein K00102 LDHD; D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4] D MTLP_11320 transcriptional regulator K22373 larA; lactate racemase [EC:5.1.2.1] D MTLP_04960 malate dehydrogenase K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D MTLP_04970 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D MTLP_04980 fumarate hydratase K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D MTLP_03990 hypothetical protein K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] D MTLP_10450 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D MTLP_05150 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MTLP_00410 citramalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:melu00630] D MTLP_05150 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MTLP_08970 methylmalonyl-CoA mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D MTLP_01360 methylmalonyl-CoA mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D MTLP_08960 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D MTLP_01370 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D MTLP_00320 hypothetical protein K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14] D MTLP_12250 katB; catalase K03781 katE; catalase [EC:1.11.1.6] D MTLP_09440 phosphoglycolate phosphatase K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18] D MTLP_04260 glnA_2; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MTLP_01980 glnA_1; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MTLP_02850 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00640 Propanoate metabolism [PATH:melu00640] D MTLP_05590 Acetyl-CoA ligase/synthetase I (AMP-forming) subunit A K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D MTLP_04170 Acetyl-CoA synthetase II (AMP-forming) subunit A K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D MTLP_09860 Acetyl-CoA synthetase II (AMP-forming) subunit B K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] D MTLP_07890 CoA-binding protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D MTLP_12410 acyl-CoA synthetase K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D MTLP_13010 hypothetical protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D MTLP_04530 porA; Pyruvate synthase subunit A K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D MTLP_04520 porB; Pyruvate synthase subunit B K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D MTLP_04550 porC_2; Pyruvate synthase subunit C K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D MTLP_04540 porC_1; Pyruvate synthase subunit D K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D MTLP_08970 methylmalonyl-CoA mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D MTLP_01360 methylmalonyl-CoA mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D MTLP_08960 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D MTLP_01370 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] C 00650 Butanoate metabolism [PATH:melu00650] D MTLP_05150 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MTLP_01420 hbd; 3-hydroxybutyryl-CoA dehydrogenase K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] D MTLP_01410 crotonase K01715 crt; enoyl-CoA hydratase [EC:4.2.1.17] D MTLP_10110 phaC; class III poly(R)-hydroxyalkanoic acid synthase subunit PhaC K03821 phaC; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304] D MTLP_10120 phbC; poly-beta-hydroxybutyrate polymerase K03821 phaC; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304] D MTLP_04530 porA; Pyruvate synthase subunit A K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D MTLP_04520 porB; Pyruvate synthase subunit B K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D MTLP_04550 porC_2; Pyruvate synthase subunit C K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D MTLP_04540 porC_1; Pyruvate synthase subunit D K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D MTLP_05080 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D MTLP_11500 ilvB; acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D MTLP_11510 acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] C 00660 C5-Branched dibasic acid metabolism [PATH:melu00660] D MTLP_11500 ilvB; acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D MTLP_11510 acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D MTLP_11490 2-isopropylmalate synthase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21] D MTLP_11290 leuC1; 3-isopropylmalate dehydratase large subunit 1 K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D MTLP_02810 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D MTLP_08850 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D MTLP_11280 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D MTLP_04380 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] C 00562 Inositol phosphate metabolism [PATH:melu00562] D MTLP_02700 fructose 1,6-bisphosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D MTLP_04020 triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:melu00190] D MTLP_10940 ATP synthase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] D MTLP_10930 ATP synthase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B D MTLP_10960 ATP synthase subunit C K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C D MTLP_10920 ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D D MTLP_10970 ATP synthase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E D MTLP_10950 ATP synthase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F D MTLP_11000 hypothetical protein K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H D MTLP_10990 ATP synthase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I D MTLP_10980 ATP synthase subunit K K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K D MTLP_10100 manganese-dependent inorganic pyrophosphatase K15986 ppaC; manganese-dependent inorganic pyrophosphatase [EC:3.6.1.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation by Calvin cycle [PATH:melu00710] D MTLP_12060 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D MTLP_05710 glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] D MTLP_05720 ribose-5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] D MTLP_04020 triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D MTLP_03990 hypothetical protein K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] C 00720 Other carbon fixation pathways [PATH:melu00720] D MTLP_04530 porA; Pyruvate synthase subunit A K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D MTLP_04520 porB; Pyruvate synthase subunit B K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D MTLP_04550 porC_2; Pyruvate synthase subunit C K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D MTLP_04540 porC_1; Pyruvate synthase subunit D K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D MTLP_10450 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D MTLP_04970 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D MTLP_04980 fumarate hydratase K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D MTLP_05150 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MTLP_03440 enoyl-CoA hydratase K15019 K15019; 3-hydroxypropionyl-coenzyme A dehydratase [EC:4.2.1.116] D MTLP_08960 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D MTLP_01370 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D MTLP_08970 methylmalonyl-CoA mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D MTLP_01360 methylmalonyl-CoA mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D MTLP_05400 acetyl-CoA synthase subunit E K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] D MTLP_05390 cdhD; acetyl-CoA synthase subunit D K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245] C 00680 Methane metabolism [PATH:melu00680] D MTLP_07180 acetyl-CoA synthase subunit alpha K00192 cdhA; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit alpha [EC:1.2.7.4] D MTLP_07170 acetyl-CoA synthase subunit beta K00195 cdhB; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit epsilon D MTLP_05360 acetyl-CoA synthase subunit subunit C K00193 cdhC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit beta [EC:2.3.1.169] D MTLP_05400 acetyl-CoA synthase subunit E K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] D MTLP_05390 cdhD; acetyl-CoA synthase subunit D K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245] D MTLP_02850 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D MTLP_10760 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D MTLP_04030 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D MTLP_01120 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D MTLP_11470 hypothetical protein K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D MTLP_05990 fae_1; 3-hexulose-6-phosphate synthase K13812 fae-hps; bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43] D MTLP_12130 (Fe-S)-cluster assembly protein K13831 hps-phi; 3-hexulose-6-phosphate synthase / 6-phospho-3-hexuloisomerase [EC:4.1.2.43 5.3.1.27] D MTLP_12000 formylmethanofuran dehydrogenase subunit A K00200 fwdA; formylmethanofuran dehydrogenase subunit A [EC:1.2.7.12] D MTLP_07470 formylmethanofuran dehydrogenase subunit B K00201 fwdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.7.12] D MTLP_10300 formylmethanofuran dehydrogenase subunit B K00201 fwdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.7.12] D MTLP_12010 formylmethanofuran dehydrogenase subunit B K00201 fwdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.7.12] D MTLP_11990 formylmethanofuran dehydrogenase subunit C K00202 fwdC; formylmethanofuran dehydrogenase subunit C [EC:1.2.7.12] D MTLP_07460 hypothetical protein K00203 fwdD; formylmethanofuran dehydrogenase subunit D [EC:1.2.7.12] D MTLP_10310 formylmethanofuran dehydrogenase subunit D K00203 fwdD; formylmethanofuran dehydrogenase subunit D [EC:1.2.7.12] D MTLP_12020 Formylmethanofuran dehydrogenase, subunit D K00203 fwdD; formylmethanofuran dehydrogenase subunit D [EC:1.2.7.12] D MTLP_04140 hypothetical protein K00205 fwdF; 4Fe-4S ferredoxin D MTLP_11370 hypothetical protein K00205 fwdF; 4Fe-4S ferredoxin D MTLP_13320 polyferredoxin K00205 fwdF; 4Fe-4S ferredoxin D MTLP_00230 hypothetical protein K00205 fwdF; 4Fe-4S ferredoxin D MTLP_07480 tRNA CCA-pyrophosphorylase K11260 fwdG; 4Fe-4S ferredoxin D MTLP_07060 formylmethanofuran dehydrogenase subunit E K11261 fwdE; formylmethanofuran dehydrogenase subunit E [EC:1.2.7.12] D MTLP_04500 fhcD; formylmethanofuran--tetrahydromethanopterin formyltransferase K00672 ftr; formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101] D MTLP_05130 formylmethanofuran--tetrahydromethanopterin formyltransferase K00672 ftr; formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101] D MTLP_03080 N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase K01499 mch; methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27] D MTLP_05520 methylenetetrahydromethanopterin dehydrogenase K10714 mtdB; methylene-tetrahydromethanopterin dehydrogenase [EC:1.5.1.-] D MTLP_06280 fae_2; formaldehyde-activating enzyme K10713 fae; 5,6,7,8-tetrahydromethanopterin hydro-lyase [EC:4.2.1.147] D MTLP_01530 5,10-methylenetetrahydromethanopterin reductase K00320 mer; 5,10-methylenetetrahydromethanopterin reductase [EC:1.5.98.2] D MTLP_08750 tetrahydromethanopterin S-methyltransferase subunit A K00577 mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:7.2.1.4] D MTLP_08740 tetrahydromethanopterin S-methyltransferase subunit B K00578 mtrB; tetrahydromethanopterin S-methyltransferase subunit B [EC:7.2.1.4] D MTLP_08730 mtrC; tetrahydromethanopterin S-methyltransferase subunit C K00579 mtrC; tetrahydromethanopterin S-methyltransferase subunit C [EC:7.2.1.4] D MTLP_08720 mtrD; tetrahydromethanopterin S-methyltransferase subunit D K00580 mtrD; tetrahydromethanopterin S-methyltransferase subunit D [EC:7.2.1.4] D MTLP_08710 tetrahydromethanopterin S-methyltransferase subunit E K00581 mtrE; tetrahydromethanopterin S-methyltransferase subunit E [EC:7.2.1.4] D MTLP_08770 tetrahydromethanopterin S-methyltransferase subunit G K00583 mtrG; tetrahydromethanopterin S-methyltransferase subunit G [EC:7.2.1.4] D MTLP_08780 tetrahydromethanopterin S-methyltransferase subunit H K00584 mtrH; tetrahydromethanopterin S-methyltransferase subunit H [EC:7.2.1.4] D MTLP_00200 Alkyl-coenzyme M reductase subunit alpha K00399 mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1] D MTLP_01300 methyl-coenzyme M reductase subunit alpha K00399 mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1] D MTLP_07770 atwA; methyl coenzyme M reductase system, component A2 K00400 K00400; methyl coenzyme M reductase system, component A2 D MTLP_00190 ABC-type glutathione transport system K00400 K00400; methyl coenzyme M reductase system, component A2 D MTLP_00280 ABC-type glutathione transport system K00400 K00400; methyl coenzyme M reductase system, component A2 D MTLP_00390 ABC transporter ATP-binding protein K00400 K00400; methyl coenzyme M reductase system, component A2 D MTLP_00220 Alkyl-coenzyme M reductase subunit beta K00401 mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1] D MTLP_01260 mcrB; methyl-coenzyme M reductase subunit beta K00401 mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1] D MTLP_00210 Alkyl-coenzyme M reductase subunit gamma K00402 mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1] D MTLP_01290 methyl-coenzyme M reductase subunit gamma K00402 mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1] D MTLP_00250 Alkyl-coenzyme M reductase operon protein C K03421 mcrC; methyl-coenzyme M reductase subunit C D MTLP_01280 methyl-coenzyme M reductase operon protein C K03421 mcrC; methyl-coenzyme M reductase subunit C D MTLP_00260 Alkyl-coenzyme M reductase operon protein D K03422 mcrD; methyl-coenzyme M reductase subunit D D MTLP_01270 mcrD; methyl-coenzyme M reductase operon protein D K03422 mcrD; methyl-coenzyme M reductase subunit D D MTLP_04930 hypothetical protein K22481 hdrB1; heterodisulfide reductase subunit B1 [EC:1.8.7.3] D MTLP_04100 heterodisulfide reductase A K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D MTLP_04150 hypothetical protein K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D MTLP_06700 disulfide reductase K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D MTLP_13310 disulfide reductase K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D MTLP_03950 Heterodisulfide reductase subunit A K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D MTLP_03930 Heterodisulfide reductase subunit B K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D MTLP_03940 Heterodisulfide reductase subunit C K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D MTLP_11950 hypothetical protein K08264 hdrD; heterodisulfide reductase subunit D [EC:1.8.98.1] D MTLP_04090 MvhD; methyl-viologen-reducing hydrogenase delta subunit K14127 mvhD; F420-non-reducing hydrogenase iron-sulfur subunit [EC:1.12.99.- 1.8.98.5 1.8.98.6] D MTLP_04530 porA; Pyruvate synthase subunit A K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D MTLP_04520 porB; Pyruvate synthase subunit B K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D MTLP_04550 porC_2; Pyruvate synthase subunit C K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D MTLP_04540 porC_1; Pyruvate synthase subunit D K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D MTLP_10450 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D MTLP_09200 phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D MTLP_12590 phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D MTLP_03730 3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D MTLP_02840 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D MTLP_02880 phosphosulfolactate synthase K08097 comA; phosphosulfolactate synthase [EC:4.4.1.19] D MTLP_02870 comB; putative 2-phosphosulfolactate phosphatase K05979 comB; 2-phosphosulfolactate phosphatase [EC:3.1.3.71] D MTLP_02860 sulfopyruvate decarboxylase K24393 comDE; sulfopyruvate decarboxylase [EC:4.1.1.79] D MTLP_05340 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofH K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147] D MTLP_05330 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG K11780 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [EC:4.3.1.32] D MTLP_05320 cofC; 2-phospho-L-lactate guanylyltransferase K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105] D MTLP_06820 2-phospho-L-lactate transferase K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28] D MTLP_05040 F420-0--gamma-glutamyl ligase K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34] D MTLP_10440 tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] D MTLP_02150 hypothetical protein K06914 mfnD; tyramine---L-glutamate ligase [EC:6.3.4.24] D MTLP_07540 hypothetical protein K09733 mfnB; (5-formylfuran-3-yl)methyl phosphate synthase [EC:4.2.3.153] D MTLP_12140 amino acid kinase K07144 mfnE; 5-(aminomethyl)-3-furanmethanol phosphate kinase [EC:2.7.4.31] D MTLP_02160 hypothetical protein K07072 mfnF; (4-(4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl)furan-2-yl)methanamine synthase [EC:2.5.1.131] C 00910 Nitrogen metabolism [PATH:melu00910] D MTLP_05670 nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH D MTLP_04260 glnA_2; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MTLP_01980 glnA_1; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MTLP_05500 glutamate synthase (NADPH), homotetrameric K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D MTLP_06690 aspB; oxidoreductase K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] C 00920 Sulfur metabolism [PATH:melu00920] D MTLP_03220 sulfonate ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D MTLP_03210 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein D MTLP_03200 nitrate ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D MTLP_02690 cysC; adenylyl-sulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25] D MTLP_08620 ferredoxin--nitrite reductase K00392 sir; sulfite reductase (ferredoxin) [EC:1.8.7.1] D MTLP_06380 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:melu00061] D MTLP_01430 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase FabG K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D MTLP_06230 fabK; 2-nitropropane dioxygenase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9] D MTLP_11150 AMP-dependent CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MTLP_00070 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MTLP_01160 AMP-dependent CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:melu00071] D MTLP_05150 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MTLP_01450 3-ketoacyl-CoA thiolase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D MTLP_07290 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D MTLP_11150 AMP-dependent CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MTLP_00070 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MTLP_01160 AMP-dependent CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism C 00564 Glycerophospholipid metabolism [PATH:melu00564] D MTLP_03900 glycerol-1-phosphate dehydrogenase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261] D MTLP_01470 geranylgeranylglyceryl/heptaprenylglyceryl phosphate synthase K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41] D MTLP_04880 prenyltransferase K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42] D MTLP_08250 hypothetical protein K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42] D MTLP_10280 hypothetical protein K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67] D MTLP_05820 digeranylgeranylglycerophospholipid reductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11] D MTLP_05840 digeranylgeranylglycerophospholipid reductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11] D MTLP_09940 digeranylgeranylglycerophospholipid reductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism [PATH:melu00592] D MTLP_01450 3-ketoacyl-CoA thiolase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D MTLP_07290 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:melu00230] D MTLP_00950 DNA mismatch repair protein MutT K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D MTLP_10320 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D MTLP_10660 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D MTLP_10580 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D MTLP_09210 phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D MTLP_12700 phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D MTLP_03810 phosphoribosylformylglycinamidine synthase K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3] D MTLP_03820 phosphoribosylformylglycinamidine synthase K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3] D MTLP_02770 phosphoribosylformylglycinamidine synthase K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D MTLP_10780 phosphoribosylaminoimidazole synthetase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D MTLP_07510 N5-carboxyaminoimidazole ribonucleotide mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D MTLP_09830 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D MTLP_10250 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D MTLP_01840 purH; bifunctional purine biosynthesis protein PurH K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D MTLP_04510 IMP cyclohydrolase K11176 purO; IMP cyclohydrolase [EC:3.5.4.10] D MTLP_05010 hypothetical protein K20881 yrfG; GMP/IMP 5'-nucleotidase [EC:3.1.3.-] D MTLP_07530 IMP dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D MTLP_05460 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D MTLP_12650 non-canonical purine NTP pyrophosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D MTLP_09600 GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D MTLP_03360 GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D MTLP_09370 nrdD; anaerobic ribonucleoside triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D MTLP_09050 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D MTLP_13380 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D MTLP_03390 kinase K18532 AK6; adenylate kinase [EC:2.7.4.3] D MTLP_09650 hydrolase K19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53] D MTLP_02690 cysC; adenylyl-sulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25] C 00240 Pyrimidine metabolism [PATH:melu00240] D MTLP_03160 carbamoyl phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D MTLP_03170 carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D MTLP_09500 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D MTLP_09510 aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D MTLP_09810 dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3] D MTLP_02480 dihydroorotate dehydrogenase K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14] D MTLP_02490 dihydroorotate dehydrogenase electron transfer subunit K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit D MTLP_06900 orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D MTLP_11140 pyrF; orotidine-5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D MTLP_05890 uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D MTLP_05460 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D MTLP_03350 pyrG; CTP synthetase K01937 pyrG; CTP synthase [EC:6.3.4.2] D MTLP_00830 cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D MTLP_09370 nrdD; anaerobic ribonucleoside triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D MTLP_13080 cytidine deaminase K01493 comEB; dCMP deaminase [EC:3.5.4.12] D MTLP_10340 thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D MTLP_10350 thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D MTLP_01500 thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D MTLP_03490 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:melu00250] D MTLP_09070 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D MTLP_06390 carbon-nitrogen hydrolase K13566 NIT2; omega-amidase [EC:3.5.1.3] D MTLP_08660 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D MTLP_11170 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D MTLP_09050 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D MTLP_10250 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D MTLP_09500 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D MTLP_09510 aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D MTLP_05500 glutamate synthase (NADPH), homotetrameric K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D MTLP_06690 aspB; oxidoreductase K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D MTLP_04260 glnA_2; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MTLP_01980 glnA_1; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MTLP_03160 carbamoyl phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D MTLP_03170 carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D MTLP_02770 phosphoribosylformylglycinamidine synthase K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D MTLP_10580 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:melu00260] D MTLP_01990 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D MTLP_04160 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D MTLP_08480 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D MTLP_11900 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D MTLP_02850 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D MTLP_09200 phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D MTLP_12590 phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D MTLP_03730 3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D MTLP_02840 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D MTLP_12760 gbsA; betaine aldehyde dehydrogenase K00130 betB; betaine-aldehyde dehydrogenase [EC:1.2.1.8] D MTLP_10550 tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D MTLP_10540 tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D MTLP_07210 trpB; tryptophan synthase beta chain K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D MTLP_12960 ectB; diaminobutyrate--2-oxoglutarate transaminase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76] D MTLP_12970 ectA; L-2,4-diaminobutyric acid acetyltransferase K06718 ectA; L-2,4-diaminobutyric acid acetyltransferase [EC:2.3.1.178] D MTLP_12950 ectC; L-ectoine synthase K06720 ectC; L-ectoine synthase [EC:4.2.1.108] C 00270 Cysteine and methionine metabolism [PATH:melu00270] D MTLP_11700 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D MTLP_10620 S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D MTLP_01540 S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D MTLP_01550 speE; polyamine aminopropyltransferase K00797 speE; spermidine synthase [EC:2.5.1.16] D MTLP_08120 mtnP; S-methyl-5'-thioadenosine phosphorylase K00772 mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28] D MTLP_03190 S-methyl-5-thioribose-1-phosphate isomerase K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23] D MTLP_13270 L-methionine gamma-lyase K01761 E4.4.1.11; methionine-gamma-lyase [EC:4.4.1.11] D MTLP_05200 ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D MTLP_01990 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D MTLP_04160 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D MTLP_08480 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D MTLP_06200 hypothetical protein K23975 E2.8.1.16; L-aspartate semialdehyde sulfurtransferase [EC:2.8.1.16] D MTLP_06190 ferredoxin K23976 K23976; L-aspartate semialdehyde sulfurtransferase ferredoxin D MTLP_05190 branched chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D MTLP_09070 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D MTLP_06380 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D MTLP_03730 3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] C 00280 Valine, leucine and isoleucine degradation [PATH:melu00280] D MTLP_05190 branched chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D MTLP_01450 3-ketoacyl-CoA thiolase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D MTLP_07290 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D MTLP_08970 methylmalonyl-CoA mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D MTLP_01360 methylmalonyl-CoA mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D MTLP_08960 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D MTLP_01370 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D MTLP_05150 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MTLP_05080 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:melu00290] D MTLP_11490 2-isopropylmalate synthase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21] D MTLP_11290 leuC1; 3-isopropylmalate dehydratase large subunit 1 K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D MTLP_02810 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D MTLP_08850 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D MTLP_11280 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D MTLP_04380 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D MTLP_11500 ilvB; acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D MTLP_11510 acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D MTLP_11520 ilvC; ketol-acid reductoisomerase (NADP(+)) K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D MTLP_12990 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D MTLP_05190 branched chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D MTLP_00410 citramalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00300 Lysine biosynthesis [PATH:melu00300] D MTLP_08480 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D MTLP_01990 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D MTLP_04160 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D MTLP_01780 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D MTLP_01790 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] D MTLP_03370 aspartate aminotransferase family protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D MTLP_05760 succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D MTLP_02640 diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D MTLP_02620 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D MTLP_13020 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D MTLP_02630 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] C 00310 Lysine degradation [PATH:melu00310] D MTLP_05150 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MTLP_06670 hypothetical protein K01843 kamA; lysine 2,3-aminomutase [EC:5.4.3.2] C 00220 Arginine biosynthesis [PATH:melu00220] D MTLP_09220 argF; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D MTLP_08660 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D MTLP_11170 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D MTLP_02770 phosphoribosylformylglycinamidine synthase K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D MTLP_04260 glnA_2; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MTLP_01980 glnA_1; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MTLP_03160 carbamoyl phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D MTLP_03170 carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D MTLP_09070 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D MTLP_11230 ornithine acetyltransferase K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] D MTLP_11240 acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8] D MTLP_13090 N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] D MTLP_03370 aspartate aminotransferase family protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] C 00330 Arginine and proline metabolism [PATH:melu00330] D MTLP_03880 pyruvoyl-dependent arginine decarboxylase K02626 pdaD; arginine decarboxylase [EC:4.1.1.19] D MTLP_12820 speB; agmatinase K01480 speB; agmatinase [EC:3.5.3.11] D MTLP_01550 speE; polyamine aminopropyltransferase K00797 speE; spermidine synthase [EC:2.5.1.16] D MTLP_01540 S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D MTLP_09070 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] C 00340 Histidine metabolism [PATH:melu00340] D MTLP_03500 hisG; ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17] D MTLP_06620 phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] D MTLP_07550 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D MTLP_07580 hisA; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino] imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D MTLP_07970 hisH; imidazole glycerol phosphate synthase subunit HisH K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] D MTLP_05620 imidazole glycerol phosphate synthase cyclase subunit K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] D MTLP_07570 imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19] D MTLP_03380 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D MTLP_03540 histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23] C 00350 Tyrosine metabolism [PATH:melu00350] D MTLP_09070 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D MTLP_03380 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D MTLP_10440 tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] C 00360 Phenylalanine metabolism [PATH:melu00360] D MTLP_03430 phenylacetate--CoA ligase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30] D MTLP_01420 hbd; 3-hydroxybutyryl-CoA dehydrogenase K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] D MTLP_09070 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D MTLP_03380 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00380 Tryptophan metabolism [PATH:melu00380] D MTLP_05150 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MTLP_12250 katB; catalase K03781 katE; catalase [EC:1.11.1.6] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:melu00400] D MTLP_01120 fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D MTLP_01130 3-dehydroquinate synthase II K11646 K11646; 3-dehydroquinate synthase II [EC:1.4.1.24] D MTLP_01140 3-dehydroquinase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10] D MTLP_06920 shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D MTLP_02120 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D MTLP_02140 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D MTLP_02130 chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D MTLP_10520 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D MTLP_10530 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D MTLP_10500 anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18] D MTLP_10510 N-(5'-phosphoribosyl)anthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24] D MTLP_10490 indole-3-glycerol-phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48] D MTLP_10550 tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D MTLP_10540 tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D MTLP_07210 trpB; tryptophan synthase beta chain K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D MTLP_02110 hypothetical protein K04093 pheA1; chorismate mutase [EC:5.4.99.5] D MTLP_06930 prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D MTLP_06300 pheA; prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51] D MTLP_09070 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D MTLP_03380 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism [PATH:melu00410] D MTLP_10440 tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] D MTLP_00480 hypothetical protein K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] D MTLP_03120 hypothetical protein K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] C 00430 Taurine and hypotaurine metabolism C 00440 Phosphonate and phosphinate metabolism [PATH:melu00440] D MTLP_02370 carbon-phosphorus lyase K06164 phnI; alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI [EC:2.7.8.37] D MTLP_02390 phosphonate C-P lyase system protein PhnG K06166 phnG; alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG [EC:2.7.8.37] D MTLP_02380 phnH; phosphonate C-P lyase system protein PhnH K06165 phnH; alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH [EC:2.7.8.37] D MTLP_02340 phnL; ABC transporter K05780 phnL; alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [EC:2.7.8.37] D MTLP_02330 phnM; alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase K06162 phnM; alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase [EC:3.6.1.63] D MTLP_02360 phnJ; carbon-phosphorus lyase complex subunit PhnJ K06163 phnJ; alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase [EC:4.7.1.1] C 00450 Selenocompound metabolism [PATH:melu00450] D MTLP_11700 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D MTLP_13270 L-methionine gamma-lyase K01761 E4.4.1.11; methionine-gamma-lyase [EC:4.4.1.11] D MTLP_02560 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism D MTLP_02850 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:melu00470] D MTLP_02610 hypothetical protein K01775 alr; alanine racemase [EC:5.1.1.1] D MTLP_06650 hypothetical protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D MTLP_02770 phosphoribosylformylglycinamidine synthase K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D MTLP_02640 diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D MTLP_13020 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D MTLP_02630 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] C 00480 Glutathione metabolism [PATH:melu00480] D MTLP_01550 speE; polyamine aminopropyltransferase K00797 speE; spermidine synthase [EC:2.5.1.16] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis C 00541 O-Antigen nucleotide sugar biosynthesis C 00550 Peptidoglycan biosynthesis C 00552 Teichoic acid biosynthesis C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:melu00730] D MTLP_07250 phosphomethylpyrimidine synthase K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17] D MTLP_01760 thiD; bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3] D MTLP_05880 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D MTLP_08340 hypothetical protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D MTLP_07010 ribose 1,5-bisphosphate isomerase K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] D MTLP_06330 thiL; thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16] D MTLP_13380 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:melu00740] D MTLP_05680 ribD2; 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302] D MTLP_12030 diaminohydroxyphosphoribosylaminopyrimidine reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302] D MTLP_08840 3,4-dihydroxy-2-butanone-4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12] D MTLP_09740 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D MTLP_09750 riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9] D MTLP_08830 riboflavin kinase K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161] D MTLP_10720 FAD synthase K14656 ribL; FAD synthetase [EC:2.7.7.2] D MTLP_00950 DNA mismatch repair protein MutT K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D MTLP_06710 aromatic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00750 Vitamin B6 metabolism [PATH:melu00750] D MTLP_11900 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D MTLP_11650 pyridoxal 5'-phosphate synthase lyase subunit PdxS K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6] D MTLP_11640 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6] C 00760 Nicotinate and nicotinamide metabolism [PATH:melu00760] D MTLP_09930 aspartate dehydrogenase K06989 nadX; aspartate dehydrogenase [EC:1.4.1.21] D MTLP_08170 quinolinate synthase K03517 nadA; quinolinate synthase [EC:2.5.1.72] D MTLP_03890 nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D MTLP_06810 nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21] D MTLP_01510 nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1] D MTLP_08070 NAD+ synthase K01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1] D MTLP_03680 NAD+ synthase K01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1] D MTLP_12920 NAD-dependent deacetylase K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313] D MTLP_06910 hypothetical protein K00858 ppnK; NAD+ kinase [EC:2.7.1.23] C 00770 Pantothenate and CoA biosynthesis [PATH:melu00770] D MTLP_11500 ilvB; acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D MTLP_11510 acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D MTLP_11520 ilvC; ketol-acid reductoisomerase (NADP(+)) K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D MTLP_12990 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D MTLP_06010 2-dehydropantoate 2-reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169] D MTLP_03130 pantothenate kinase K06982 pok; pantoate kinase [EC:2.7.1.169] D MTLP_00480 hypothetical protein K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] D MTLP_03120 hypothetical protein K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] D MTLP_03140 phosphopantothenoylcysteine decarboxylase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D MTLP_02990 hypothetical protein K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237] D MTLP_05190 branched chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D MTLP_10440 tyrosine decarboxylase MfnA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] C 00780 Biotin metabolism [PATH:melu00780] D MTLP_01430 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase FabG K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C 00785 Lipoic acid metabolism C 00790 Folate biosynthesis [PATH:melu00790] D MTLP_12680 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D MTLP_12690 folC; bifunctional folylpolyglutamate synthase/dihydrofolate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D MTLP_06270 6-carboxytetrahydropterin synthase QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D MTLP_06260 queE; 7-carboxy-7-deazaguanine synthase K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D MTLP_06250 queC; 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D MTLP_02220 GTP cyclohydrolase I FolE2 K17488 mptA; GTP cyclohydrolase IV [EC:3.5.4.39] D MTLP_10210 hypothetical protein K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D MTLP_10770 hypothetical protein K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54] D MTLP_11020 MBL fold hydrolase K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105] D MTLP_13210 MBL fold hydrolase K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105] D MTLP_01110 MBL fold hydrolase K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105] D MTLP_05120 GTP 3',8-cyclase MoaA K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D MTLP_03550 cyclic pyranopterin monophosphate synthase MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D MTLP_02750 moaE; molybdopterin synthase catalytic subunit K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D MTLP_03800 molybdenum cofactor biosynthesis protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D MTLP_11040 molybdopterin molybdenumtransferase MoeA K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] D MTLP_10680 molybdenum cofactor guanylyltransferase K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77] C 00670 One carbon pool by folate [PATH:melu00670] D MTLP_02850 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D MTLP_12700 phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D MTLP_01840 purH; bifunctional purine biosynthesis protein PurH K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D MTLP_03490 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:melu00860] D MTLP_01920 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D MTLP_04300 glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70] D MTLP_06720 hemL; aspartate aminotransferase family protein K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D MTLP_04310 delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D MTLP_06730 hydroxymethylbilane synthase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61] D MTLP_12470 uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D MTLP_00370 Uroporphyrinogen decarboxylase family protein K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37] D MTLP_06740 uroporphyrinogen-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] D MTLP_04290 hypothetical protein K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76] D MTLP_03870 sirohydrochlorin nickelochelatase K22011 cfbA; sirohydrochlorin cobalto/nickelchelatase [EC:4.99.1.3 4.99.1.11] D MTLP_06360 precorrin-2 C(20)-methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151] D MTLP_07370 hypothetical protein K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272] D MTLP_06350 cobalt-precorrin-4 C(11)-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271] D MTLP_07360 cobalamin biosynthesis protein K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12] D MTLP_07390 cobalt-precorrin-6A synthase K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195] D MTLP_06370 hypothetical protein K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196] D MTLP_07400 cbiE; cobalt-precorrin-7 (C(5))-methyltransferase K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289] D MTLP_07380 precorrin-8X methylmutase K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60] D MTLP_06220 Ni-sirohydrochlorin a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11] D MTLP_08990 cob(I)alamin adenosyltransferase/cobinamide ATP-dependent adenosyltransferase K19221 cobA; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D MTLP_11960 cobyric acid synthase CobQ K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10] D MTLP_11980 cobalamin biosynthesis protein K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10] D MTLP_08190 adenosylcobinamide amidohydrolase K08260 cbiZ; adenosylcobinamide hydrolase [EC:3.5.1.90] D MTLP_07350 adenosylcobinamide-phosphate guanylyltransferase K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62] D MTLP_07340 cobS; adenosylcobinamide-GDP ribazoletransferase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26] D MTLP_10000 cobT; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase K00768 E2.4.2.21; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [EC:2.4.2.21] D MTLP_11970 hypothetical protein K04720 cobD; threonine-phosphate decarboxylase [EC:4.1.1.81] D MTLP_01910 Ni-sirohydrochlorin a,c-diamide synthase K22012 cfbB; Ni-sirohydrochlorin a,c-diamide synthase [EC:6.3.5.12] D MTLP_03850 Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit K21611 cfbD; Ni-sirohydrochlorin a,c-diamide reductive cyclase subunit CfbD [EC:6.3.3.7] D MTLP_03860 hypothetical protein K21612 cfbE; coenzyme F430 synthetase [EC:6.4.1.9] D MTLP_12380 magnesium chelatase subunit H K03403 chlH; magnesium chelatase subunit H [EC:6.6.1.1] D MTLP_12490 magnesium chelatase subunit H K03403 chlH; magnesium chelatase subunit H [EC:6.6.1.1] D MTLP_12480 hypothetical protein K03404 chlD; magnesium chelatase subunit D [EC:6.6.1.1] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis D MTLP_06710 aromatic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:melu00900] D MTLP_05150 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MTLP_05080 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D MTLP_08900 3-hydroxy-3-methylglutaryl-CoA reductase K00054 mvaA; hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88] D MTLP_00470 mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36] D MTLP_11460 amino acid kinase K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26] D MTLP_11110 hypothetical protein K09128 acnX2; phosphomecalonate degydratase small subunit [EC:4.2.1.182] D MTLP_06710 aromatic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D MTLP_01940 fni; type 2 isopentenyl-diphosphate Delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] D MTLP_05810 serralysin K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D MTLP_05850 serralysin K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D MTLP_01930 geranylgeranyl pyrophosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D MTLP_09580 hypothetical protein K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation [PATH:melu00907] D MTLP_01450 3-ketoacyl-CoA thiolase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D MTLP_07290 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis C 00261 Monobactam biosynthesis [PATH:melu00261] D MTLP_01990 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D MTLP_04160 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D MTLP_01780 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D MTLP_01790 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:melu00521] D MTLP_10320 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D MTLP_02700 fructose 1,6-bisphosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] C 00524 Neomycin, kanamycin and gentamicin biosynthesis C 00525 Acarbose and validamycin biosynthesis C 00401 Novobiocin biosynthesis [PATH:melu00401] D MTLP_06930 prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D MTLP_09070 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D MTLP_03380 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D MTLP_10520 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D MTLP_10530 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis D MTLP_01430 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase FabG K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics C 00999 Biosynthesis of various plant secondary metabolites [PATH:melu00999] D MTLP_10620 S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D MTLP_06920 shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation [PATH:melu00362] D MTLP_01450 3-ketoacyl-CoA thiolase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D MTLP_07290 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D MTLP_01420 hbd; 3-hydroxybutyryl-CoA dehydrogenase K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] D MTLP_05150 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00627 Aminobenzoate degradation [PATH:melu00627] D MTLP_01170 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D MTLP_06710 aromatic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation D MTLP_05670 nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH C 00361 Chlorocyclohexane and chlorobenzene degradation C 00623 Toluene degradation C 00622 Xylene degradation C 00633 Nitrotoluene degradation D MTLP_04530 porA; Pyruvate synthase subunit A K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D MTLP_04520 porB; Pyruvate synthase subunit B K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D MTLP_04550 porC_2; Pyruvate synthase subunit C K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D MTLP_04540 porC_1; Pyruvate synthase subunit D K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] C 00642 Ethylbenzene degradation D MTLP_01450 3-ketoacyl-CoA thiolase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D MTLP_07290 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] C 00643 Styrene degradation C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation C 00626 Naphthalene degradation C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:melu03020] D MTLP_09350 DNA-directed RNA polymerase subunit B K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6] D MTLP_09340 rpoA1; DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6] D MTLP_09330 DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6] D MTLP_00880 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6] D MTLP_10400 hypothetical protein K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6] D MTLP_02970 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6] D MTLP_04340 DNA-directed RNA polymerase subunit F K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6] D MTLP_09360 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6] D MTLP_07160 rpoK; DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6] D MTLP_00920 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6] C 03022 Basal transcription factors [PATH:melu03022] D MTLP_08460 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D MTLP_01220 transcription factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D MTLP_06860 transcription factor K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:melu03010] D MTLP_00930 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D MTLP_00650 hypothetical protein K02982 RP-S3; small subunit ribosomal protein S3 D MTLP_00860 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D MTLP_00780 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D MTLP_09290 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D MTLP_00730 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D MTLP_00910 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D MTLP_09260 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D MTLP_00870 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D MTLP_09300 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D MTLP_00850 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D MTLP_12640 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D MTLP_00680 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D MTLP_00630 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D MTLP_12600 30S ribosomal protein S3ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae D MTLP_00710 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e D MTLP_05440 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e D MTLP_05210 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e D MTLP_01770 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e D MTLP_01740 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e D MTLP_03000 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e D MTLP_11410 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e D MTLP_03010 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D MTLP_05480 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e D MTLP_09790 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D MTLP_00620 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D MTLP_00590 rpl3p; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D MTLP_00720 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D MTLP_00740 rpl6p; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D MTLP_09780 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D MTLP_01850 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D MTLP_09770 50S ribosomal protein P1 K02869 RP-L12; large subunit ribosomal protein L12 D MTLP_00900 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D MTLP_00690 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D MTLP_00800 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D MTLP_00770 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D MTLP_00640 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D MTLP_00610 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D MTLP_00700 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D MTLP_00660 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D MTLP_00790 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D MTLP_00600 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e D MTLP_05490 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D MTLP_13470 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e D MTLP_11530 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e D MTLP_00890 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e D MTLP_00760 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e D MTLP_04350 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e D MTLP_05470 hypothetical protein K02896 RP-L24e; large subunit ribosomal protein L24e D MTLP_09320 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e D MTLP_01700 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e D MTLP_00750 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e D MTLP_10590 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e D MTLP_11610 50S ribosomal protein L37ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae D MTLP_01710 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e D MTLP_05930 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D MTLP_11400 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e D MTLP_r00020 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:melu00970] D MTLP_t00130 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D MTLP_01920 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D MTLP_00560 gatA; aspartyl/glutamyl-tRNA amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D MTLP_00550 aspartyl/glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D MTLP_11670 gatC; aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D MTLP_11160 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7] D MTLP_05300 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7] D MTLP_11890 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D MTLP_03530 aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D MTLP_08590 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D MTLP_07850 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D MTLP_12610 serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D MTLP_06560 O-phosphoserine--tRNA ligase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27] D MTLP_12980 O-phospho-L-seryl-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73] D MTLP_02560 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D MTLP_09530 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D MTLP_08010 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D MTLP_10220 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D MTLP_03510 lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D MTLP_03100 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D MTLP_00570 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D MTLP_01620 histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D MTLP_08520 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D MTLP_08510 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D MTLP_10240 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D MTLP_08530 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:melu03060] D MTLP_00810 preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D MTLP_07830 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD D MTLP_07840 preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF D MTLP_01660 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D MTLP_01670 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D MTLP_01870 hypothetical protein K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D MTLP_02650 signal recognition particle protein Srp19 K03105 SRP19; signal recognition particle subunit SRP19 D MTLP_06470 anion transporter K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D MTLP_03270 S26 family signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:melu04122] D MTLP_05880 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D MTLP_06380 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D MTLP_02750 moaE; molybdopterin synthase catalytic subunit K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D MTLP_05120 GTP 3',8-cyclase MoaA K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D MTLP_03550 cyclic pyranopterin monophosphate synthase MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D MTLP_03800 molybdenum cofactor biosynthesis protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D MTLP_08340 hypothetical protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] C 03050 Proteasome [PATH:melu03050] D MTLP_08290 proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit D MTLP_11560 psmA; proteasome subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D MTLP_01810 psmB; proteasome subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] C 03018 RNA degradation [PATH:melu03018] D MTLP_10410 hypothetical protein K07573 CSL4; exosome complex component CSL4 D MTLP_11580 RNA-binding protein K03679 RRP4; exosome complex component RRP4 D MTLP_11600 RNA-binding protein K12589 RRP42; exosome complex component RRP42 D MTLP_11590 exosome complex exonuclease Rrp41 K11600 RRP41; exosome complex component RRP41 D MTLP_10760 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D MTLP_05250 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK B B 09124 Replication and repair C 03030 DNA replication [PATH:melu03030] D MTLP_08890 hypothetical protein K02316 dnaG; DNA primase [EC:2.7.7.101] D MTLP_02520 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D MTLP_09630 hypothetical protein K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D MTLP_03280 hypothetical protein K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7] D MTLP_03290 DNA polymerase II large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7] D MTLP_02000 ATPase AAA K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D MTLP_11380 DNA primase small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102] D MTLP_10200 DNA primase large subunit K18882 priL; DNA primase large subunit D MTLP_08410 DNA polymerase III sliding clamp K04802 PCNA; proliferating cell nuclear antigen D MTLP_05730 ATPase AAA K04801 rfcS; replication factor C small subunit D MTLP_01580 replication protein C K04801 rfcS; replication factor C small subunit D MTLP_01900 hypothetical protein K04800 rfcL; replication factor C large subunit D MTLP_03770 endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D MTLP_09610 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03410 Base excision repair [PATH:melu03410] D MTLP_08630 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D MTLP_08410 DNA polymerase III sliding clamp K04802 PCNA; proliferating cell nuclear antigen D MTLP_03770 endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D MTLP_09610 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D MTLP_13430 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D MTLP_13370 recombinase RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] C 03420 Nucleotide excision repair [PATH:melu03420] D MTLP_08410 DNA polymerase III sliding clamp K04802 PCNA; proliferating cell nuclear antigen D MTLP_09610 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03430 Mismatch repair [PATH:melu03430] D MTLP_09250 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS D MTLP_09240 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL D MTLP_13370 recombinase RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D MTLP_08410 DNA polymerase III sliding clamp K04802 PCNA; proliferating cell nuclear antigen D MTLP_09610 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03440 Homologous recombination D MTLP_13370 recombinase RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] C 03450 Non-homologous end-joining D MTLP_03770 endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 D MTLP_02980 DNA-directed RNA polymerase subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D MTLP_01860 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5 C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:melu02010] D MTLP_08580 tungstate ABC transporter substrate-binding protein WtpA K15495 wtpA; molybdate/tungstate transport system substrate-binding protein D MTLP_08570 molybdenum ABC transporter permease K15496 wtpB; molybdate/tungstate transport system permease protein D MTLP_08560 sulfate ABC transporter ATP-binding protein K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6] D MTLP_03220 sulfonate ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D MTLP_03210 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein D MTLP_03200 nitrate ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D MTLP_07670 molybdenum ABC transporter substrate-binding protein K02020 modA; molybdate transport system substrate-binding protein D MTLP_07680 molybdate ABC transporter permease K02018 modB; molybdate transport system permease protein D MTLP_07690 sulfate ABC transporter ATP-binding protein K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D MTLP_07110 phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D MTLP_07130 phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D MTLP_07100 pstC; phosphate ABC transporter permease subunit PstC K02037 pstC; phosphate transport system permease protein D MTLP_07090 hypothetical protein K02038 pstA; phosphate transport system permease protein D MTLP_07070 phoT; phosphate import ATP-binding protein PstB K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D MTLP_02420 phosphonates-binding protein K02044 phnD; phosphonate transport system substrate-binding protein D MTLP_02400 phnE; phosphonate ABC transporter, permease protein PhnE K02042 phnE; phosphonate transport system permease protein D MTLP_02410 phnC; phosphonates import ATP-binding protein PhnC K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2] D MTLP_00490 adhesin K09815 znuA; zinc transport system substrate-binding protein D MTLP_00510 metal ABC transporter permease K09816 znuB; zinc transport system permease protein D MTLP_00500 zinc ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D MTLP_09160 hypothetical protein K02009 cbiN; cobalt/nickel transport protein D MTLP_09150 cbiM; cobalt transport protein CbiM K02007 cbiM; cobalt/nickel transport system permease protein D MTLP_09180 hypothetical protein K02008 cbiQ; cobalt/nickel transport system permease protein D MTLP_09190 cobalt ABC transporter ATP-binding protein K02006 cbiO; cobalt/nickel transport system ATP-binding protein C 02060 Phosphotransferase system (PTS) C 03070 Bacterial secretion system [PATH:melu03070] D MTLP_07830 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD D MTLP_07840 preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF D MTLP_00810 preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D MTLP_01670 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D MTLP_01660 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] B B 09132 Signal transduction C 02020 Two-component system [PATH:melu02020] D MTLP_07110 phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D MTLP_07130 phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D MTLP_05770 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52] D MTLP_04960 malate dehydrogenase K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D MTLP_04270 glnB; nitrogen regulatory protein P-II K04751 glnB; nitrogen regulatory protein P-II 1 D MTLP_04260 glnA_2; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MTLP_01980 glnA_1; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MTLP_05150 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:melu02024] D MTLP_10520 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D MTLP_10530 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D MTLP_11150 AMP-dependent CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MTLP_00070 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MTLP_01160 AMP-dependent CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MTLP_00810 preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D MTLP_01670 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D MTLP_01660 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis C 02040 Flagellar assembly C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D MTLP_10760 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism D MTLP_08980 methylmalonyl Co-A mutase-associated GTPase MeaB K07588 MMAA; GTPase [EC:3.6.5.-] D MTLP_01350 methylmalonyl Co-A mutase-associated GTPase MeaB K07588 MMAA; GTPase [EC:3.6.5.-] C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance C 01502 Vancomycin resistance [PATH:melu01502] D MTLP_06650 hypothetical protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D MTLP_02610 hypothetical protein K01775 alr; alanine racemase [EC:5.1.1.1] C 01503 Cationic antimicrobial peptide (CAMP) resistance B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:melu01000] C 01001 Protein kinases [BR:melu01001] D MTLP_12660 hypothetical protein K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1] D MTLP_02540 serine/threonine protein kinase K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] D MTLP_06580 serine/threonine protein kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1] C 01009 Protein phosphatases and associated proteins [BR:melu01009] D MTLP_05200 ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D MTLP_02840 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] C 01002 Peptidases and inhibitors [BR:melu01002] D MTLP_06170 hypothetical protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D MTLP_09600 GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D MTLP_03360 GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D MTLP_10580 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D MTLP_08380 archaeosortase A K24447 artA; archaeosortase A [EC:3.4.22.-] D MTLP_05760 succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D MTLP_02940 type II methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D MTLP_02930 peptidase M24 family protein K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D MTLP_09480 heat-shock protein HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D MTLP_09040 peptidase K06974 amzA; archaemetzincin [EC:3.4.-.-] D MTLP_07600 hypothetical protein K17734 aprX; serine protease AprX [EC:3.4.21.-] D MTLP_11340 ATP-dependent protease LonB K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53] D MTLP_03270 S26 family signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89] D MTLP_07950 sppA; multidrug transporter K04773 sppA; protease IV [EC:3.4.21.-] D MTLP_04010 hypothetical protein K04773 sppA; protease IV [EC:3.4.21.-] D MTLP_06850 rhomboid family intramembrane serine protease K07059 K07059; rhomboid family protein D MTLP_11560 psmA; proteasome subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D MTLP_01810 psmB; proteasome subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D MTLP_11360 PmbA protein K03592 pmbA; PmbA protein D MTLP_11350 PmbA/TldD family protein K03568 tldD; TldD protein C 01003 Glycosyltransferases C 01005 Lipopolysaccharide biosynthesis proteins C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:melu01011] D MTLP_06650 hypothetical protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D MTLP_02610 hypothetical protein K01775 alr; alanine racemase [EC:5.1.1.1] D MTLP_08380 archaeosortase A K24447 artA; archaeosortase A [EC:3.4.22.-] C 01004 Lipid biosynthesis proteins [BR:melu01004] D MTLP_01430 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase FabG K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D MTLP_06230 fabK; 2-nitropropane dioxygenase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9] D MTLP_05590 Acetyl-CoA ligase/synthetase I (AMP-forming) subunit A K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D MTLP_04170 Acetyl-CoA synthetase II (AMP-forming) subunit A K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] D MTLP_09860 Acetyl-CoA synthetase II (AMP-forming) subunit B K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] D MTLP_07890 CoA-binding protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D MTLP_12410 acyl-CoA synthetase K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D MTLP_13010 hypothetical protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D MTLP_11150 AMP-dependent CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MTLP_00070 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MTLP_01160 AMP-dependent CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:melu01006] D MTLP_05810 serralysin K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D MTLP_05850 serralysin K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D MTLP_01930 geranylgeranyl pyrophosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D MTLP_09580 hypothetical protein K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90] C 01007 Amino acid related enzymes [BR:melu01007] D MTLP_03510 lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D MTLP_01920 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D MTLP_10240 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D MTLP_08530 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D MTLP_03100 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D MTLP_02560 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D MTLP_10220 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D MTLP_09530 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D MTLP_08010 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D MTLP_03530 aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D MTLP_01620 histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D MTLP_08590 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D MTLP_12610 serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D MTLP_00570 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D MTLP_07850 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D MTLP_11890 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D MTLP_06560 O-phosphoserine--tRNA ligase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27] D MTLP_08520 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D MTLP_08510 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D MTLP_09070 pyridoxal phosphate-dependent aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D MTLP_02620 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D MTLP_08350 aromatic amino acid aminotransferase K10907 K10907; aminotransferase [EC:2.6.1.-] D MTLP_03380 histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D MTLP_03370 aspartate aminotransferase family protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D MTLP_12960 ectB; diaminobutyrate--2-oxoglutarate transaminase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76] D MTLP_06720 hemL; aspartate aminotransferase family protein K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D MTLP_05190 branched chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:melu03000] D MTLP_01220 transcription factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D MTLP_06240 transcriptional regulator K07721 K07721; ArsR family transcriptional regulator D MTLP_01590 DNA-binding protein K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D MTLP_06780 iron-dependent repressor K11924 mntR; DtxR family transcriptional regulator, manganese transport regulator D MTLP_10690 tfx; transcriptional regulator K09714 tfx; HTH-type transcriptional regulator, fmd operon transcriptional regulator D MTLP_08000 orotate phosphoribosyltransferase K26599 gfcR; HTH-type transcriptional regulator, activator of D-glucose/D-fructose catabolism D MTLP_09820 transcriptional regulator K07728 K07728; putative transcriptional regulator D MTLP_11780 transcriptional regulator K07729 K07729; putative transcriptional regulator D MTLP_05960 Crp/Fnr family transcriptional regulator K07730 K07730; putative transcriptional regulator D MTLP_07520 nickel-responsive transcriptional regulator NikR K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator C 03021 Transcription machinery [BR:melu03021] D MTLP_08460 tfb; transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D MTLP_01220 transcription factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D MTLP_06860 transcription factor K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha D MTLP_02980 DNA-directed RNA polymerase subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D MTLP_01860 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5 D MTLP_09670 GTPase K24104 GPN; GPN-loop GTPase D MTLP_09310 transcription elongation factor NusA K02600 nusA; transcription termination/antitermination protein NusA D MTLP_09340 rpoA1; DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6] D MTLP_09330 DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6] D MTLP_09350 DNA-directed RNA polymerase subunit B K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6] D MTLP_00880 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6] D MTLP_02970 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6] D MTLP_04340 DNA-directed RNA polymerase subunit F K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6] D MTLP_09360 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6] D MTLP_07160 rpoK; DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6] D MTLP_10400 hypothetical protein K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6] D MTLP_00920 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6] D MTLP_08400 DNA-directed RNA polymerase subunit M K03057 tfs; transcription factor S C 03019 Messenger RNA biogenesis [BR:melu03019] D MTLP_02980 DNA-directed RNA polymerase subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D MTLP_01860 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5 D MTLP_09400 ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D MTLP_04180 mRNA surveillance protein Pelota K06965 PELO; protein pelota D MTLP_03110 peptide chain release factor 1 K03265 ETF1; peptide chain release factor subunit 1 D MTLP_09270 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha D MTLP_10410 hypothetical protein K07573 CSL4; exosome complex component CSL4 D MTLP_11580 RNA-binding protein K03679 RRP4; exosome complex component RRP4 D MTLP_11590 exosome complex exonuclease Rrp41 K11600 RRP41; exosome complex component RRP41 D MTLP_11600 RNA-binding protein K12589 RRP42; exosome complex component RRP42 D MTLP_10760 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D MTLP_05250 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK C 03041 Spliceosome C 03011 Ribosome [BR:melu03011] D MTLP_12600 30S ribosomal protein S3ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae D MTLP_00710 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e D MTLP_05440 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e D MTLP_05210 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e D MTLP_01770 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e D MTLP_01740 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e D MTLP_03000 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e D MTLP_11410 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e D MTLP_03010 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D MTLP_05480 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e D MTLP_00600 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e D MTLP_05490 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D MTLP_13470 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e D MTLP_11530 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e D MTLP_00890 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e D MTLP_00760 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e D MTLP_04350 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e D MTLP_05470 hypothetical protein K02896 RP-L24e; large subunit ribosomal protein L24e D MTLP_09320 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e D MTLP_01700 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e D MTLP_00750 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e D MTLP_10590 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e D MTLP_11610 50S ribosomal protein L37ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae D MTLP_01710 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e D MTLP_05930 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D MTLP_11400 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e D MTLP_00930 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D MTLP_00650 hypothetical protein K02982 RP-S3; small subunit ribosomal protein S3 D MTLP_00860 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D MTLP_00780 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D MTLP_09290 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D MTLP_00730 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D MTLP_00910 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D MTLP_09260 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D MTLP_00870 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D MTLP_09300 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D MTLP_00850 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D MTLP_12640 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D MTLP_00680 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D MTLP_00630 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D MTLP_09790 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D MTLP_00620 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D MTLP_00590 rpl3p; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D MTLP_00720 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D MTLP_00740 rpl6p; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D MTLP_09780 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D MTLP_01850 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D MTLP_00900 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D MTLP_00690 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D MTLP_00800 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D MTLP_00770 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D MTLP_00640 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D MTLP_00610 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D MTLP_00700 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D MTLP_00660 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D MTLP_00790 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D MTLP_09770 50S ribosomal protein P1 K02869 RP-L12; large subunit ribosomal protein L12 D MTLP_r00020 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:melu03009] D MTLP_13450 hypothetical protein K14564 NOP56; nucleolar protein 56 D MTLP_02550 RNA-processing protein K06961 KRR1; ribosomal RNA assembly protein D MTLP_02540 serine/threonine protein kinase K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] D MTLP_06580 serine/threonine protein kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1] D MTLP_03390 kinase K18532 AK6; adenylate kinase [EC:2.7.4.3] D MTLP_11220 ribosome biogenesis/translation initiation ATPase RLI K06174 ABCE1; ATP-binding cassette, sub-family E, member 1 D MTLP_01490 GTP-binding protein K06943 NOG1; nucleolar GTP-binding protein D MTLP_00670 ribonuclease P K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D MTLP_11550 ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D MTLP_11540 hypothetical protein K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D MTLP_01690 translation initiation factor IF-6 K03264 EIF6; translation initiation factor 6 D MTLP_05170 hypothetical protein K07562 NMD3; 60S ribosomal export protein NMD3 D MTLP_11570 ribosome assembly factor SBDS K14574 SDO1; ribosome maturation protein SDO1 D MTLP_09400 ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D MTLP_02210 GTP-binding protein K03595 era; GTPase D MTLP_13460 fibrillarin-like rRNA methylase K04795 flpA; fibrillarin-like pre-rRNA processing protein D MTLP_05490 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D MTLP_09310 transcription elongation factor NusA K02600 nusA; transcription termination/antitermination protein NusA D MTLP_04320 hypothetical protein K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D MTLP_09900 hypothetical protein K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D MTLP_01640 rimI; ribosomal-protein-alanine N-acetyltransferase RimI K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D MTLP_08270 hypothetical protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D MTLP_03150 ychF; translation-associated GTPase K06942 ychF; ribosome-binding ATPase C 03016 Transfer RNA biogenesis [BR:melu03016] D MTLP_00670 ribonuclease P K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D MTLP_11550 ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D MTLP_11540 hypothetical protein K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D MTLP_02890 ribonuclease P K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5] D MTLP_09850 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11] D MTLP_03710 RNA-splicing ligase RtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8] D MTLP_03700 archease K24956 ZBTB8OS; protein archease D MTLP_09270 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha D MTLP_01920 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D MTLP_00570 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D MTLP_10220 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D MTLP_08010 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D MTLP_02560 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D MTLP_03100 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D MTLP_11890 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D MTLP_08590 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D MTLP_07850 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D MTLP_12610 serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D MTLP_09530 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D MTLP_01620 histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D MTLP_08520 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D MTLP_08510 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D MTLP_10240 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D MTLP_08530 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D MTLP_07860 threonylcarbamoyladenosine tRNA methylthiotransferase K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5] D MTLP_13400 tRNA (guanine(10)-N(2))-dimethyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216] D MTLP_07000 tRNA methyltransferase K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D MTLP_12210 SAM-dependent methyltransferase K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D MTLP_03470 4-demethylwyosine synthase TYW1 K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44] D MTLP_02780 hypothetical protein K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282] D MTLP_06880 tRNA pseudouridine(38-40) synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D MTLP_00840 tRNA pseudouridine(55) synthase TruB K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D MTLP_05910 tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27] D MTLP_04360 tRNA pseudouridine(54/55) synthase Pus10 K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25] D MTLP_05880 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D MTLP_12660 hypothetical protein K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1] D MTLP_12670 hypothetical protein K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234] D MTLP_11270 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311] D MTLP_08270 hypothetical protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D MTLP_12090 CCA-adding protein K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72] D MTLP_04910 tRNA-intron lyase K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16] D MTLP_12080 RNA 2',3'-cyclic phosphodiesterase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58] D MTLP_07790 RNA 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-] D MTLP_03510 lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D MTLP_03530 aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D MTLP_06560 O-phosphoserine--tRNA ligase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27] D MTLP_12980 O-phospho-L-seryl-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73] D MTLP_01890 RNA methyltransferase K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-] D MTLP_08310 tRNA (pseudouridine(54)-N(1))-methyltransferase TrmY K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257] D MTLP_08430 tRNA (guanine-N2)-dimethyltransferase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213] D MTLP_00530 hypothetical protein K09119 cgi121; KEOPS complex subunit Cgi121 D MTLP_11620 hypothetical protein K09741 pcc1; KEOPS complex subunit Pcc1 D MTLP_06250 queC; 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D MTLP_06270 6-carboxytetrahydropterin synthase QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D MTLP_06260 queE; 7-carboxy-7-deazaguanine synthase K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D MTLP_07920 tRNA-guanine(15) transglycosylase K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48] D MTLP_08340 hypothetical protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D MTLP_08490 tRNA(Ile2) 2-agmatinylcytidine synthetase K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22] C 03012 Translation factors [BR:melu03012] D MTLP_10230 translation initiation factor IF-1 K03236 EIF1A; translation initiation factor 1A D MTLP_08680 stress response translation initiation inhibitor YciH K03113 EIF1; translation initiation factor 1 D MTLP_11420 translation initiation factor IF-2 subunit alpha K03237 EIF2S1; translation initiation factor 2 subunit 1 D MTLP_02950 translation initiation factor IF-2 subunit gamma K03242 EIF2S3; translation initiation factor 2 subunit 3 D MTLP_12830 translation initiation factor IF-5A K03263 EIF5A; translation initiation factor 5A D MTLP_05450 translation initiation factor IF-2 K03243 EIF5B; translation initiation factor 5B D MTLP_01690 translation initiation factor IF-6 K03264 EIF6; translation initiation factor 6 D MTLP_09270 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha D MTLP_05750 effector protein K03232 EEF1B; elongation factor 1-beta D MTLP_09280 translation elongation factor aEF-2 K03234 EEF2; elongation factor 2 D MTLP_10430 dph2; diphthamide biosynthesis enzyme Dph2 K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108] D MTLP_08060 TIGR00289 family protein K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14] D MTLP_03110 peptide chain release factor 1 K03265 ETF1; peptide chain release factor subunit 1 D MTLP_08500 protoporphyrinogen oxidase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D MTLP_05920 peptidyl-tRNA hydrolase K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29] C 03110 Chaperones and folding catalysts [BR:melu03110] D MTLP_12440 clpB; chaperone protein ClpB K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB D MTLP_05250 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK D MTLP_13420 thermosome subunit K22447 cct; archaeal chaperonin D MTLP_03690 thermosome subunit K22447 cct; archaeal chaperonin D MTLP_05240 molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ D MTLP_05260 hypothetical protein K03687 GRPE; molecular chaperone GrpE D MTLP_05610 hypothetical protein K13993 HSP20; HSP20 family protein D MTLP_12430 heat-shock protein K13993 HSP20; HSP20 family protein D MTLP_13410 hypothetical protein K13993 HSP20; HSP20 family protein D MTLP_01680 hypothetical protein K04797 pfdA; prefoldin alpha subunit D MTLP_11630 prefoldin subunit beta K04798 pfdB; prefoldin beta subunit D MTLP_03920 peptidylprolyl isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8] D MTLP_05430 thiol reductase thioredoxin K03671 TXN; thioredoxin D MTLP_05650 thioredoxin K03671 TXN; thioredoxin C 04131 Membrane trafficking [BR:melu04131] D MTLP_05460 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D MTLP_09400 ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D MTLP_06470 anion transporter K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D MTLP_01870 hypothetical protein K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D MTLP_09270 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha C 04121 Ubiquitin system [BR:melu04121] D MTLP_05930 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D MTLP_03010 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae C 03051 Proteasome [BR:melu03051] D MTLP_11560 psmA; proteasome subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D MTLP_01810 psmB; proteasome subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D MTLP_08290 proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit C 03032 DNA replication proteins [BR:melu03032] D MTLP_08410 DNA polymerase III sliding clamp K04802 PCNA; proliferating cell nuclear antigen D MTLP_03770 endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D MTLP_09610 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D MTLP_08890 hypothetical protein K02316 dnaG; DNA primase [EC:2.7.7.101] D MTLP_07020 cell division control protein Cdc6 K10725 cdc6A; archaeal cell division control protein 6 D MTLP_02000 ATPase AAA K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D MTLP_11380 DNA primase small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102] D MTLP_10200 DNA primase large subunit K18882 priL; DNA primase large subunit D MTLP_11390 hypothetical protein K09723 ginS; DNA replication factor GINS D MTLP_02520 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D MTLP_09630 hypothetical protein K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D MTLP_03290 DNA polymerase II large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7] D MTLP_03280 hypothetical protein K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7] D MTLP_01900 hypothetical protein K04800 rfcL; replication factor C large subunit D MTLP_05730 ATPase AAA K04801 rfcS; replication factor C small subunit D MTLP_01580 replication protein C K04801 rfcS; replication factor C small subunit D MTLP_06610 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D MTLP_06600 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D MTLP_00540 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] C 03036 Chromosome and associated proteins [BR:melu03036] D MTLP_07980 histone K24450 hmf; DNA-binding protein D MTLP_13390 histone K24450 hmf; DNA-binding protein D MTLP_05570 ftsZ_2; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D MTLP_01880 ftsZ_1; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D MTLP_06980 hypothetical protein K04763 xerD; integrase/recombinase XerD C 03400 DNA repair and recombination proteins [BR:melu03400] D MTLP_08630 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D MTLP_08410 DNA polymerase III sliding clamp K04802 PCNA; proliferating cell nuclear antigen D MTLP_03770 endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D MTLP_09610 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D MTLP_08390 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MTLP_13430 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D MTLP_06550 endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7] D MTLP_13370 recombinase RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D MTLP_09250 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS D MTLP_09240 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL D MTLP_07040 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50 D MTLP_07030 double-stranded DNA repair protein Mre11 K03547 sbcD; DNA repair protein SbcD/Mre11 D MTLP_09430 radA; DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA D MTLP_09420 DNA repair and recombination protein RadB K04484 radB; DNA repair protein RadB D MTLP_09700 Holliday junction DNA helicase K03552 hjr; holliday junction resolvase [EC:3.1.21.10] D MTLP_00520 extensin K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4] D MTLP_06610 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D MTLP_06600 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D MTLP_00540 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D MTLP_11660 dpbF; DNA polymerase/3'-5' exonuclease PolX K02347 polX; DNA polymerase (family X) D MTLP_06970 helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] D MTLP_08150 hypothetical protein K22585 nreA; DNA repair protein NreA C 03029 Mitochondrial biogenesis [BR:melu03029] D MTLP_00670 ribonuclease P K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D MTLP_11550 ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D MTLP_11540 hypothetical protein K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D MTLP_02210 GTP-binding protein K03595 era; GTPase D MTLP_10240 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D MTLP_08010 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D MTLP_08590 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D MTLP_03100 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D MTLP_00560 gatA; aspartyl/glutamyl-tRNA amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D MTLP_00550 aspartyl/glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D MTLP_11670 gatC; aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D MTLP_05250 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK D MTLP_05260 hypothetical protein K03687 GRPE; molecular chaperone GrpE D MTLP_05240 molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ D MTLP_05880 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7] B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:melu02000] D MTLP_07670 molybdenum ABC transporter substrate-binding protein K02020 modA; molybdate transport system substrate-binding protein D MTLP_07680 molybdate ABC transporter permease K02018 modB; molybdate transport system permease protein D MTLP_07690 sulfate ABC transporter ATP-binding protein K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D MTLP_08580 tungstate ABC transporter substrate-binding protein WtpA K15495 wtpA; molybdate/tungstate transport system substrate-binding protein D MTLP_08570 molybdenum ABC transporter permease K15496 wtpB; molybdate/tungstate transport system permease protein D MTLP_08560 sulfate ABC transporter ATP-binding protein K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6] D MTLP_03220 sulfonate ABC transporter substrate-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D MTLP_03210 ABC transporter permease K15554 ssuC; sulfonate transport system permease protein D MTLP_03200 nitrate ABC transporter ATP-binding protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D MTLP_07110 phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D MTLP_07130 phosphate ABC transporter substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D MTLP_07100 pstC; phosphate ABC transporter permease subunit PstC K02037 pstC; phosphate transport system permease protein D MTLP_07090 hypothetical protein K02038 pstA; phosphate transport system permease protein D MTLP_07070 phoT; phosphate import ATP-binding protein PstB K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D MTLP_02420 phosphonates-binding protein K02044 phnD; phosphonate transport system substrate-binding protein D MTLP_02400 phnE; phosphonate ABC transporter, permease protein PhnE K02042 phnE; phosphonate transport system permease protein D MTLP_02410 phnC; phosphonates import ATP-binding protein PhnC K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2] D MTLP_07650 iron ABC transporter substrate-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D MTLP_12310 iron ABC transporter substrate-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D MTLP_12520 hypothetical protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D MTLP_12530 hypothetical protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D MTLP_13130 iron ABC transporter substrate-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D MTLP_07660 iron ABC transporter permease K02015 ABC.FEV.P; iron complex transport system permease protein D MTLP_12320 iron ABC transporter permease K02015 ABC.FEV.P; iron complex transport system permease protein D MTLP_12510 iron ABC transporter permease K02015 ABC.FEV.P; iron complex transport system permease protein D MTLP_13120 iron ABC transporter permease K02015 ABC.FEV.P; iron complex transport system permease protein D MTLP_07630 ABC transporter ATP-binding protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-] D MTLP_12330 ABC transporter ATP-binding protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-] D MTLP_12500 ABC transporter ATP-binding protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-] D MTLP_13110 ABC transporter ATP-binding protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-] D MTLP_07280 ABC transporter substrate-binding protein K25034 btuF; cobalamin transport system substrate-binding protein D MTLP_07270 iron ABC transporter K25027 btuC; cobalamin transport system permease protein D MTLP_07260 iron ABC transporter ATP-binding protein K25028 btuD; cobalamin transport system ATP-binding protein [EC:7.6.2.8] D MTLP_00490 adhesin K09815 znuA; zinc transport system substrate-binding protein D MTLP_00510 metal ABC transporter permease K09816 znuB; zinc transport system permease protein D MTLP_00500 zinc ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D MTLP_09160 hypothetical protein K02009 cbiN; cobalt/nickel transport protein D MTLP_09180 hypothetical protein K02008 cbiQ; cobalt/nickel transport system permease protein D MTLP_09150 cbiM; cobalt transport protein CbiM K02007 cbiM; cobalt/nickel transport system permease protein D MTLP_09190 cobalt ABC transporter ATP-binding protein K02006 cbiO; cobalt/nickel transport system ATP-binding protein D MTLP_09560 multidrug ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein D MTLP_09540 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D MTLP_09550 daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D MTLP_01150 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D MTLP_08040 hypothetical protein K02004 ABC.CD.P; putative ABC transport system permease protein D MTLP_02040 hypothetical protein K02004 ABC.CD.P; putative ABC transport system permease protein D MTLP_08030 putative ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D MTLP_02030 macrolide ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D MTLP_08860 ABC transporter ATP-binding protein K09013 sufC; Fe-S cluster assembly ATP-binding protein D MTLP_04280 ammonium transporter K03320 amt; ammonium transporter, Amt family D MTLP_11060 divalent cation transporter K07244 K07244; mgtE-like transporter D MTLP_04740 hypothetical protein K03312 gltS; glutamate:Na+ symporter, ESS family D MTLP_04780 hypothetical protein K03312 gltS; glutamate:Na+ symporter, ESS family D MTLP_02510 Trk system potassium transporter TrkH K03498 trkH; trk/ktr system potassium uptake protein D MTLP_02530 trkA; potassium transporter peripheral membrane protein K03499 trkA; trk/ktr system potassium uptake protein D MTLP_06470 anion transporter K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D MTLP_11090 arsenical-resistance protein K03325 ACR3; arsenite transporter D MTLP_10080 hypothetical protein K05571 mnhG; multicomponent Na+:H+ antiporter subunit G D MTLP_01600 ferrous iron transporter B K04759 feoB; ferrous iron transport protein B C 02044 Secretion system [BR:melu02044] D MTLP_03640 hypothetical protein K07325 flaB; archaeal flagellin FlaB D MTLP_03610 flagellar protein FlaF K07329 flaF; archaeal flagellar protein FlaF D MTLP_03620 hypothetical protein K07330 flaG; archaeal flagellar protein FlaG D MTLP_03600 flagellar accessory protein FlaH K07331 flaH; archaeal flagellar protein FlaH D MTLP_03590 secretion system protein E K07332 flaI; archaeal flagellar protein FlaI D MTLP_03580 flagellar assembly protein J K07333 flaJ; archaeal flagellar protein FlaJ D MTLP_06170 hypothetical protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D MTLP_13080 cytidine deaminase K01493 comEB; dCMP deaminase [EC:3.5.4.12] D MTLP_07830 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD D MTLP_07840 preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF D MTLP_00810 preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D MTLP_01660 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D MTLP_01670 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D MTLP_01870 hypothetical protein K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D MTLP_02650 signal recognition particle protein Srp19 K03105 SRP19; signal recognition particle subunit SRP19 C 02042 Bacterial toxins C 02022 Two-component system C 02035 Bacterial motility proteins [BR:melu02035] D MTLP_03640 hypothetical protein K07325 flaB; archaeal flagellin FlaB D MTLP_03610 flagellar protein FlaF K07329 flaF; archaeal flagellar protein FlaF D MTLP_03620 hypothetical protein K07330 flaG; archaeal flagellar protein FlaG D MTLP_03600 flagellar accessory protein FlaH K07331 flaH; archaeal flagellar protein FlaH D MTLP_03590 secretion system protein E K07332 flaI; archaeal flagellar protein FlaI D MTLP_03580 flagellar assembly protein J K07333 flaJ; archaeal flagellar protein FlaJ D MTLP_06170 hypothetical protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:melu04812] D MTLP_00940 amrB; hypothetical protein K06990 MEMO1; MEMO1 family protein D MTLP_05570 ftsZ_2; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D MTLP_01880 ftsZ_1; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ C 04147 Exosome [BR:melu04147] D MTLP_10760 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D MTLP_12060 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D MTLP_09270 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha D MTLP_09280 translation elongation factor aEF-2 K03234 EEF2; elongation factor 2 D MTLP_05250 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK D MTLP_03770 endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D MTLP_07530 IMP dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D MTLP_03010 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D MTLP_09400 ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D MTLP_11150 AMP-dependent CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MTLP_00070 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MTLP_01160 AMP-dependent CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MTLP_05150 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MTLP_05200 ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D MTLP_13380 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D MTLP_11170 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D MTLP_08660 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D MTLP_04260 glnA_2; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MTLP_01980 glnA_1; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MTLP_04310 delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D MTLP_03730 3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D MTLP_01840 purH; bifunctional purine biosynthesis protein PurH K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D MTLP_03960 electron transfer flavoprotein subunit alpha K03522 fixB; electron transfer flavoprotein alpha subunit D MTLP_04020 triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 02048 Prokaryotic defense system [BR:melu02048] D MTLP_01570 hypothetical protein K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D MTLP_01090 cas6; CRISPR-associated endoribonuclease K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] D MTLP_01040 type I restriction enzyme K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D MTLP_02580 type I deoxyribonuclease HsdR K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D MTLP_01030 restriction endonuclease subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D MTLP_01020 restriction endonuclease subunit S K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D MTLP_02600 DNA methyltransferase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D MTLP_04480 methyltransferase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] D MTLP_04660 hypothetical protein K24451 zim; modification methylase D MTLP_11450 methyltransferase K24451 zim; modification methylase D MTLP_02790 methyltransferase K24451 zim; modification methylase D MTLP_05570 ftsZ_2; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D MTLP_01880 ftsZ_1; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D MTLP_01920 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D MTLP_07990 DNA-binding protein K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-] D MTLP_05880 nifS; cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules C 01504 Antimicrobial resistance genes C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:melu03100] D MTLP_t00130 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D MTLP_r00020 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D MTLP_05000 iorA; indolepyruvate ferredoxin oxidoreductase subunit alpha K00179 iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8] D MTLP_04990 iorB; indolepyruvate oxidoreductase K00180 iorB; indolepyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.8] D MTLP_01520 F420H2 dehydrogenase subunit F K22162 fpoF; F420H2 dehydrogenase subunit F [EC:1.5.7.2 1.5.98.3] D MTLP_11920 pyridine nucleotide-disulfide oxidoreductase K17870 nox1; NADH oxidase (H2O2-forming) [EC:1.6.3.3] D MTLP_07880 2-nitropropane dioxygenase K23948 E1.6.5.9; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9] D MTLP_09130 putative superoxide reductase K05919 dfx; superoxide reductase [EC:1.15.1.2] D MTLP_09110 ftn; ferritin K02217 ftnA; ferritin [EC:1.16.3.2] D MTLP_05510 ferredoxin-NADP+ reductase subunit alpha K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D MTLP_10290 radical SAM protein K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5] D MTLP_06320 AmmeMemoRadiSam system radical SAM enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D MTLP_02710 hypothetical protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D MTLP_10370 radical SAM protein K04070 pflX; putative pyruvate formate lyase activating enzyme [EC:1.97.1.4] D MTLP_03790 protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] D MTLP_09690 diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98] D MTLP_08800 methanogenesis-associated radical SAM protein K25222 mmp10; [methyl coenzyme M reductase]-L-arginine C-5-methyltransferase [EC:2.1.1.379] D MTLP_04890 thymidylate synthase K22882 K22882; thymidylate synthase [EC:2.1.1.-] D MTLP_11130 deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46] D MTLP_06890 hypothetical protein K06898 larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143] D MTLP_07910 tRNA-ribosyltransferase K07557 tgtA2; archaeosine synthase alpha-subunit [EC:2.6.1.97 2.6.1.-] D MTLP_00420 TIGR01210 family radical SAM protein K06936 raSEA; archaeosine synthase beta-subunit [EC:2.6.1.-] D MTLP_12940 FAD:protein FMN transferase K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180] D MTLP_07240 hypothetical protein K18672 dacA; diadenylate cyclase [EC:2.7.7.85] D MTLP_03400 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39] D MTLP_01100 O-acetyl-ADP-ribose deacetylase K23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106] D MTLP_06340 hypothetical protein K09116 K09116; damage-control phosphatase, subfamily I [EC:3.1.3.-] D MTLP_11200 hypothetical protein K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D MTLP_04650 hypothetical protein K01174 nuc; micrococcal nuclease [EC:3.1.31.1] D MTLP_04900 N-glycosylase K03653 K03653; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] D MTLP_09800 hypothetical protein K22205 E3.13.2.3; S-adenosyl-L-methionine hydrolase (adenosine-forming) [EC:3.13.2.3] D MTLP_09030 nnr; bifunctional NAD(P)H-hydrate repair enzyme Nnr K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6] D MTLP_08330 argininosuccinate synthase K06864 larE; pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase [EC:4.4.1.37] D MTLP_09410 TIGR00299 family protein K09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12] D MTLP_09620 methanogenesis marker 1 protein K24409 ycaO; thioglycine synthase [EC:6.2.2.1] D MTLP_11750 rnfD; electron transport complex subunit D K03614 rnfD; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit D [EC:7.1.1.11 7.2.1.2] D MTLP_11760 rnfC; electron transport complex subunit C K03615 rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] D MTLP_11710 rnfB; electron transport complex protein RnfB K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] D MTLP_12200 calcium-translocating P-type ATPase, SERCA-type K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10] C 99981 Carbohydrate metabolism C 99982 Energy metabolism D MTLP_05690 hypothetical protein K02379 fdhD; FdhD protein D MTLP_11740 rnfG; electron transport complex subunit G K03612 rnfG; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit G D MTLP_11730 rnfE; electron transporter complex subunit E K03613 rnfE; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit E D MTLP_11720 rfnA; electron transport complex subunit A K03617 rnfA; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit A D MTLP_04120 electron transporter K05796 hydN; electron transport protein HydN D MTLP_11080 nifB; nitrogenase cofactor biosynthesis protein NifB K02585 nifB; nitrogen fixation protein NifB D MTLP_04040 hypothetical protein K14109 ehaR; energy-converting hydrogenase A subunit R D MTLP_08370 hypothetical protein K06862 ehbQ; energy-converting hydrogenase B subunit Q D MTLP_03970 electron transfer flavoprotein subunit beta K03521 fixA; electron transfer flavoprotein beta subunit C 99983 Lipid metabolism C 99984 Nucleotide metabolism C 99985 Amino acid metabolism C 99986 Glycan metabolism D MTLP_08450 TIGR00374 family protein K07027 K07027; glycosyltransferase 2 family protein D MTLP_13360 TIGR00374 family protein K07027 K07027; glycosyltransferase 2 family protein C 99987 Cofactor metabolism D MTLP_00350 hypothetical protein K24843 ubiT; O2-independent ubiquinone biosynthesis accessory factor UbiT D MTLP_11030 hypothetical protein K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein C 99988 Secondary metabolism C 99999 Others B B 09192 Unclassified: genetic information processing C 99973 Transcription D MTLP_08280 transcriptional regulator K03627 MBF1; putative transcription factor D MTLP_11690 DNA-binding protein K03622 ssh10b; archaea-specific DNA-binding protein D MTLP_13440 DNA-binding protein K03622 ssh10b; archaea-specific DNA-binding protein D MTLP_11310 cold-shock protein K03704 cspA; cold shock protein D MTLP_10600 small nuclear ribonucleoprotein K04796 RUXX; small nuclear ribonucleoprotein D MTLP_03740 hypothetical protein K07744 K07744; transcriptional regulator C 99974 Translation D MTLP_04330 DNA-binding protein K07572 K07572; putative nucleotide binding protein D MTLP_06310 MBL fold metallo-hydrolase K07577 K07577; putative mRNA 3-end processing factor D MTLP_10420 methyltransferase K07579 K07579; putative methylase D MTLP_05740 RNA-binding protein K07580 K07580; Zn-ribbon RNA-binding protein D MTLP_01720 alpha hydrolase K07585 K07585; tRNA methyltransferase C 99975 Protein processing D MTLP_07960 hypothetical protein K07388 K07388; hydrogenase expression/formation protein D MTLP_12070 ATPase AAA K07392 PRS2; AAA family ATPase D MTLP_04860 hypothetical protein K07398 K07398; conserved protein with predicted RNA binding PUA domain D MTLP_03560 hypothetical protein K07398 K07398; conserved protein with predicted RNA binding PUA domain C 99976 Replication and repair D MTLP_06500 hypothetical protein K07445 K07445; putative DNA methylase D MTLP_12190 transposase K07496 K07496; putative transposase C 99979 Viral proteins C 99998 Others D MTLP_09450 phage shock protein A K03969 pspA; phage shock protein A B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D MTLP_06080 sodium-dependent transporter K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family D MTLP_06440 sodium-dependent transporter K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family C 99978 Cell growth D MTLP_05380 ATP-binding protein K07321 cooC; CO dehydrogenase maturation factor D MTLP_05410 cobalamin biosynthesis protein CobN K07321 cooC; CO dehydrogenase maturation factor D MTLP_07190 hypothetical protein K06384 spoIIM; stage II sporulation protein M C 99993 Cell motility C 99995 Signaling proteins D MTLP_06450 carbon starvation protein A K06200 cstA; carbon starvation protein D MTLP_01730 hypothetical protein K06875 PDCD5; programmed cell death protein 5 C 99992 Structural proteins C 99994 Others D MTLP_07050 phoU; phosphate transport system regulatory protein PhoU K02039 phoU; phosphate transport system protein D MTLP_10810 cutA; dihydroorotate dehydrogenase K03926 cutA; periplasmic divalent cation tolerance protein D MTLP_02350 phnK; ABC transporter ATP-binding protein K05781 phnK; putative phosphonate transport system ATP-binding protein B B 09194 Poorly characterized C 99996 General function prediction only D MTLP_08870 hypothetical protein K09014 sufB; Fe-S cluster assembly protein SufB D MTLP_02170 hypothetical protein K07038 K07038; inner membrane protein D MTLP_08610 hypothetical protein K07143 K07143; UPF0148 protein D MTLP_04920 hypothetical protein K08971 K08971; putative membrane protein D MTLP_02830 hypothetical protein K08975 K08975; putative membrane protein C 99997 Function unknown D MTLP_05600 hypothetical protein K06869 K06869; uncharacterized protein D MTLP_09990 peptide-modifying radical SAM enzyme CbpB K06871 K06871; uncharacterized protein D MTLP_12420 hypothetical protein K06873 K06873; uncharacterized protein D MTLP_06830 phosphohydrolase K06885 K06885; uncharacterized protein D MTLP_06870 ATP-dependent carboligase K06913 K06913; uncharacterized protein D MTLP_10800 CoA-binding protein K06929 K06929; uncharacterized protein D MTLP_06960 phosphoesterase K06953 K06953; uncharacterized protein D MTLP_10900 hypothetical protein K07006 K07006; uncharacterized protein D MTLP_03070 hypothetical protein K07018 K07018; uncharacterized protein D MTLP_08300 hypothetical protein K07022 K07022; uncharacterized protein D MTLP_01820 hypothetical protein K07041 K07041; uncharacterized protein D MTLP_01440 hypothetical protein K07068 K07068; uncharacterized protein D MTLP_13030 hypothetical protein K07090 K07090; uncharacterized protein D MTLP_12910 phosphoesterase K07095 K07095; uncharacterized protein D MTLP_11190 hypothetical protein K07097 K07097; uncharacterized protein D MTLP_08130 phosphoribosyltransferase K07101 K07101; uncharacterized protein D MTLP_10480 hypothetical protein K07103 K07103; uncharacterized protein D MTLP_05550 methanogenesis marker 2 protein K07123 K07123; uncharacterized protein D MTLP_03720 radical SAM protein K07129 K07129; uncharacterized protein D MTLP_01970 4Fe-4S ferredoxin K07138 K07138; uncharacterized protein D MTLP_02960 DNA-binding protein K07158 K07158; uncharacterized protein D MTLP_11430 proteasome assembly chaperone family protein K07159 K07159; uncharacterized protein D MTLP_02190 Zn-ribbon containing protein K07163 K07163; uncharacterized protein D MTLP_10390 hypothetical protein K09120 K09120; uncharacterized protein D MTLP_13050 hypothetical protein K09122 K09122; uncharacterized protein D MTLP_05220 membrane protein K09129 K09129; uncharacterized protein D MTLP_03410 hypothetical protein K09131 K09131; uncharacterized protein D MTLP_07640 hypothetical protein K09138 K09138; uncharacterized protein D MTLP_01960 TIGR00296 family protein K09141 K09141; uncharacterized protein D MTLP_06570 hypothetical protein K09150 K09150; uncharacterized protein D MTLP_10610 hypothetical protein K09152 K09152; uncharacterized protein D MTLP_05780 hypothetical protein K09154 K09154; uncharacterized protein D MTLP_01650 hypothetical protein K09713 K09713; uncharacterized protein D MTLP_01560 DNA polymerase subunit beta K09717 K09717; uncharacterized protein D MTLP_08600 hypothetical protein K09721 K09721; uncharacterized protein D MTLP_09680 hypothetical protein K09728 K09728; uncharacterized protein D MTLP_03910 hypothetical protein K09730 K09730; uncharacterized protein D MTLP_05970 hypothetical protein K09737 K09737; uncharacterized protein D MTLP_06180 hypothetical protein K09740 K09740; uncharacterized protein D MTLP_02200 hypothetical protein K09743 K09743; uncharacterized protein D MTLP_09010 hypothetical protein K09807 K09807; uncharacterized protein D MTLP_05030 hypothetical protein K09989 K09989; uncharacterized protein D MTLP_01950 hypothetical protein K05967 K05967; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: June 23, 2024