+F Repair protein KO
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DNA Repair and Recombination Proteins - Micromonospora endophytica
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Jiend_28630 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Jiend_37480 putative methylated-DNA:protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Jiend_26310 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E Jiend_36590 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Jiend_05400 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E Jiend_32890 adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Jiend_32320 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E Jiend_23380 helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Jiend_26700 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Jiend_37820 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Jiend_36890 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Jiend_36900 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Jiend_11740 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Jiend_28630 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Jiend_37480 putative methylated-DNA:protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Jiend_26310 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E Jiend_36590 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Jiend_47790 mismatch-specific DNA-glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E Jiend_12330 dpo; uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Jiend_19560 hypothetical protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Jiend_37490 alkA; DNA-3-methyladenine glycosylase K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E Jiend_05400 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E Jiend_32890 adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Jiend_21820 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E Jiend_29560 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Jiend_13930 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Jiend_39050 nei_2; endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E Jiend_12530 nei_1; putative endonuclease 8 2 K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E Jiend_32320 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Jiend_08270 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E Jiend_28760 nfo_1; deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E Jiend_45490 nfo_2; putative endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E Jiend_13400 nfi; endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
D DNA ligase
E Jiend_15050 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E Jiend_46900 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E Jiend_47180 uvrA_1; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E Jiend_47010 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E Jiend_47230 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E Jiend_37040 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Jiend_38160 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Jiend_38260 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Jiend_46900 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E Jiend_15050 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F Jiend_35730 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F Jiend_35740 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F Jiend_36100 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F Jiend_06060 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F Jiend_19690 mfd; transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E Jiend_19830 hypothetical protein K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E Jiend_19850 xseB; exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E Jiend_07180 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E Jiend_28390 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Jiend_42040 holA; hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E Jiend_23910 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E Jiend_45140 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Jiend_31750 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E Jiend_15050 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E Jiend_37040 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Jiend_38160 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Jiend_38260 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Jiend_28780 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E Jiend_41510 DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E Jiend_17580 hypothetical protein K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Jiend_12300 recA; protein RecA K03553 recA; recombination protein RecA
E Jiend_07080 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Jiend_07070 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Jiend_07090 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E Jiend_06030 priA; putative primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E Jiend_11200 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Jiend_11190 sbcD; nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E Jiend_12300 recA; protein RecA K03553 recA; recombination protein RecA
E Jiend_32940 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E Jiend_28370 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E Jiend_14040 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Jiend_42330 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E Jiend_31770 recR; recombination protein RecR K06187 recR; recombination protein RecR
E Jiend_04970 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E Jiend_07080 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Jiend_07070 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Jiend_07090 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E Jiend_23420 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
E Jiend_16310 cas1-1; CRISPR-associated endonuclease Cas1 1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E Jiend_11200 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Jiend_11190 sbcD; nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E Jiend_23590 hypothetical protein K10979 ku; DNA end-binding protein Ku
E Jiend_23570 lig_1; ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E Jiend_23580 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Jiend_28330 gyrA_2; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Jiend_09260 gyrA_1; DNA topoisomerase (ATP-hydrolyzing) K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Jiend_28340 gyrB_2; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F Jiend_09270 gyrB_1; DNA topoisomerase (ATP-hydrolyzing) K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F Jiend_23970 topA_2; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F Jiend_07820 topA_1; DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F Jiend_14250 hypothetical protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F Jiend_42330 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F Jiend_31770 recR; recombination protein RecR K06187 recR; recombination protein RecR
F Jiend_15050 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F Jiend_35130 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Jiend_47320 recQ_2; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Jiend_07770 recQ_1; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Jiend_47180 uvrA_1; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F Jiend_47010 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D Jiend_45680 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D Jiend_12300 recA; protein RecA K03553 recA; recombination protein RecA
D Jiend_04970 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D Jiend_45640 DNA polymerase K14161 imuB; protein ImuB
D Jiend_45650 dnaE2; error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D Jiend_28780 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D Jiend_12290 hypothetical protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D Jiend_33920 dinG; ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D Jiend_12470 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D Jiend_26700 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Jiend_37820 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Jiend_36890 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Jiend_36900 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Jiend_14230 putative hydrolase MutT/NUDIX K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D Jiend_04880 ADP-ribose pyrophosphatase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D Jiend_11740 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Jiend_54100 ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Jiend_12090 hypothetical protein K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Jiend_54120 nrdB; ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D Jiend_12850 hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024