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Transfer RNA Biogenesis - Methanocaldococcus lauensis SG7
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
D MLAUSG7_0197 rnp; Ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D MLAUSG7_0412 rnp; Ribonuclease P protein component 2 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D MLAUSG7_1038 rnp; Ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D MLAUSG7_0162 rnp; Ribonuclease P protein component 4 K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D MLAUSG7_1094 rnz; Ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D MLAUSG7_1261 Protein archease K24956 ZBTB8OS; protein archease
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
D MLAUSG7_1531 tuf; Elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D MLAUSG7_0317 gltX; Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D MLAUSG7_1293 proS; Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D MLAUSG7_0180 ileS; Isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D MLAUSG7_0742 leuS; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D MLAUSG7_1272 metG; Methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D MLAUSG7_0474 argS; Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
C Other AARSs
D MLAUSG7_0503 alaS; Alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D MLAUSG7_0468 glyS; Glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D MLAUSG7_1070 thrS; Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D MLAUSG7_1503 serS; Type-2 serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D MLAUSG7_1224 valS; Valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D MLAUSG7_0949 hisS; Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D MLAUSG7_0419 pheS; Phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D MLAUSG7_0985 pheT; Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D MLAUSG7_0119 tyrS; Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D MLAUSG7_1166 trpS; Tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D MLAUSG7_1322 dtdA; D-aminoacyl-tRNA deacylase K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D MLAUSG7_1018 Histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
D MLAUSG7_1019 putative threonylcarbamoyladenosine tRNA methylthiotransferase K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
C Methyltransferases
D MLAUSG7_0182 trm; tRNA (guanine(26)-N(2))-dimethyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D MLAUSG7_1402 trm5b; tRNA (guanine(37)-N1)-methyltransferase Trm5b K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D MLAUSG7_1028 trmI; tRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase TrmI K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D MLAUSG7_1543 taw; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D MLAUSG7_1020 taw; tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D MLAUSG7_1217 taw; tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
C Psudouridine synthases
D MLAUSG7_1203 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D MLAUSG7_0552 truB; putative tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D MLAUSG7_0869 truD; putative tRNA pseudouridine synthase D 1 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D MLAUSG7_0967 truD; putative tRNA pseudouridine synthase D 2 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D MLAUSG7_1332 pus; tRNA pseudouridine synthase Pus10 K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
C Thiolation factors
C KEOPS/EKC complex
C Elongator complex
D MLAUSG7_1040 N-acetyltransferase domain-containing protein K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
C Elongator related proteins
C Other tRNA modification factors
D MLAUSG7_0817 Putative threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D MLAUSG7_1435 Selenide,water dikinase / selenocysteine-containing K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D MLAUSG7_0716 THUMP domain protein K06963 TAN1; tRNA acetyltransferase TAN1
D MLAUSG7_1278 THUMP domain protein K06963 TAN1; tRNA acetyltransferase TAN1
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D MLAUSG7_MISCRNA2 RNaseP_arch K01978 rnpB; RNase P catalytic RNA component
D MLAUSG7_0177 conserved protein of unknown function K09006 K09006; RNA-free ribonuclease P [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D MLAUSG7_1094 rnz; Ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D MLAUSG7_1440 cca; CCA-adding enzyme K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
B tRNA spricing factors
C tRNA splicing endonucleases
D MLAUSG7_0645 endA; tRNA-splicing endonuclease K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
C tRNA splicing ligases
C Other tRNA splicing factors
D MLAUSG7_1171 RNA 2',3'-cyclic phosphodiesterase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D MLAUSG7_0742 leuS; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D MLAUSG7_0676 lysS; Lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D MLAUSG7_1293 proS; Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D MLAUSG7_0119 tyrS; Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D MLAUSG7_1166 trpS; Tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D MLAUSG7_1070 thrS; Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D MLAUSG7_0180 ileS; Isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D MLAUSG7_0503 alaS; Alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D MLAUSG7_1224 valS; Valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D MLAUSG7_1272 metG; Methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D MLAUSG7_1503 serS; Type-2 serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D MLAUSG7_0981 conserved exported protein of unknown function K01884 cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D MLAUSG7_0317 gltX; Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D MLAUSG7_0474 argS; Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D MLAUSG7_0419 pheS; Phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D MLAUSG7_0985 pheT; Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D MLAUSG7_0949 hisS; Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D MLAUSG7_0101 aspS; Aspartate--tRNA(Asp/Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D MLAUSG7_1103 sepS; O-phosphoserine--tRNA(Cys) ligase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
D MLAUSG7_1199 O-phospho-L-seryl-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
C Trans-editing factors
D MLAUSG7_1322 dtdA; D-aminoacyl-tRNA deacylase K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferases
C Methyltransferases
D MLAUSG7_0015 trmY; tRNA (pseudouridine(54)-N(1))-methyltransferase K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257]
D MLAUSG7_1259 trm; tRNA (cytosine(48)-C(5))-methyltransferase K22901 trm4; tRNA (cytosine40_48-C5)-methyltransferase [EC:2.1.1.-]
D MLAUSG7_1461 trm; tRNA (guanine(6)-N2)-methyltransferase K16318 trm14; tRNA (guanine6-N2)-methyltransferase [EC:2.1.1.256]
D MLAUSG7_0857 trmG; tRNA (guanine(10)-N2)-dimethyltransferase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D MLAUSG7_0296 tRNA (cytidine(56)-2'-O)-methyltransferase K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
C Psudouridine synthases
D MLAUSG7_1203 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D MLAUSG7_0552 truB; putative tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D MLAUSG7_0869 truD; putative tRNA pseudouridine synthase D 1 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D MLAUSG7_0967 truD; putative tRNA pseudouridine synthase D 2 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D MLAUSG7_1398 tRNA-5-methyluridine(54) 2-sulfurtransferase K21947 ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15]
D MLAUSG7_0563 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
C KEOPS/EKC complex
D MLAUSG7_0697 tRNA N6-adenosine threonylcarbamoyltransferase / Serine/threonine-protein kinase Bud32 K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
D MLAUSG7_1381 putative KEOPS complex subunit Pcc1 K09741 pcc1; KEOPS complex subunit Pcc1
C Other tRNA modification factors
D MLAUSG7_0823 queC; 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D MLAUSG7_0026 queD; Putative 6-carboxy-5,6,7,8-tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D MLAUSG7_1229 queE; 7-carboxy-7-deazaguanine synthase K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D MLAUSG7_1435 Selenide,water dikinase / selenocysteine-containing K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D MLAUSG7_1388 Rhodanese domain protein K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D MLAUSG7_1389 conserved protein of unknown function K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D MLAUSG7_1612 tgtA; tRNA-guanine(15) transglycosylase K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D MLAUSG7_1325 thiI; putative tRNA sulfurtransferase K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D MLAUSG7_0809 tiaS; tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
D MLAUSG7_0817 Putative threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
B tRNA degradation factors
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 17, 2025