+F Repair protein KO
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DNA Repair and Recombination Proteins - Methanocaldococcus lauensis SG7
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MLAUSG7_1341 ogt; Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E MLAUSG7_1611 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
E MLAUSG7_0483 pcn; DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
E MLAUSG7_1207 fen; Flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E MLAUSG7_0395 lig; DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
E MLAUSG7_0934 rpa; Replication factor A K07466 RFA1; replication factor A1
D Other NER factors
E MLAUSG7_0395 lig; DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
E MLAUSG7_0934 rpa; Replication factor A K07466 RFA1; replication factor A1
D RFC (replication factor C)
D Other MMR factors
E MLAUSG7_0483 pcn; DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
E MLAUSG7_0395 lig; DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
E MLAUSG7_0934 rpa; Replication factor A K07466 RFA1; replication factor A1
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
D MLAUSG7_0483 pcn; DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D MLAUSG7_0945 nudF; ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MLAUSG7_0980 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MLAUSG7_1341 ogt; Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E MLAUSG7_1611 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E MLAUSG7_1029 Xylose isomerase domain protein TIM barrel K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E MLAUSG7_0327 Single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E MLAUSG7_1368 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E MLAUSG7_0948 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E MLAUSG7_1068 putative Exodeoxyribonuclease V K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E MLAUSG7_1116 rad; DNA double-strand break repair Rad50 ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E MLAUSG7_1115 mre; DNA double-strand break repair protein Mre11 K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E MLAUSG7_0327 Single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E MLAUSG7_1368 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D AddAB pathway proteins
D Other HR factor
E MLAUSG7_0695 cas; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E MLAUSG7_0584 radA; DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA
E MLAUSG7_1547 radB; DNA repair and recombination protein RadB K04484 radB; DNA repair protein RadB
E MLAUSG7_0409 hjc; Holliday junction resolvase Hjc K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
E MLAUSG7_1116 rad; DNA double-strand break repair Rad50 ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E MLAUSG7_1115 mre; DNA double-strand break repair protein Mre11 K03547 sbcD; DNA repair protein SbcD/Mre11
E MLAUSG7_0640 herA; putative DNA double-strand break repair helicase HerA K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
E MLAUSG7_1114 herA; DNA double-strand break repair helicase HerA K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
E MLAUSG7_1117 nurA; DNA double-strand break repair nuclease NurA K25510 nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-]
E MLAUSG7_0877 putative DNA helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F MLAUSG7_1443 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F MLAUSG7_0327 Single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F MLAUSG7_1368 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D MLAUSG7_0184 DEAD/DEAH box helicase domain protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D MLAUSG7_0794 ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D MLAUSG7_0945 nudF; ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MLAUSG7_0980 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024