+D GENES KO
#
KEGG Orthology (KO) - Mycoplasmoides fastidiosum
%
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:mfd00010]
D NPA10_00830 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D NPA10_02260 fba; class II fructose-1,6-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D NPA10_02770 gap; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D NPA10_02775 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D NPA10_03305 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D NPA10_03255 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NPA10_03245 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D NPA10_03950 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D NPA10_03945 alpha-ketoacid dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D NPA10_03935 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D NPA10_00040 aldehyde dehydrogenase family protein K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9]
C 00020 Citrate cycle (TCA cycle) [PATH:mfd00020]
D NPA10_03935 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D NPA10_03950 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D NPA10_03945 alpha-ketoacid dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
C 00030 Pentose phosphate pathway [PATH:mfd00030]
D NPA10_00830 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D NPA10_01775 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D NPA10_03630 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D NPA10_00385 RpiB/LacA/LacB family sugar-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D NPA10_02560 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D NPA10_00040 aldehyde dehydrogenase family protein K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9]
D NPA10_02260 fba; class II fructose-1,6-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
C 00040 Pentose and glucuronate interconversions [PATH:mfd00040]
D NPA10_02900 3-dehydro-L-gulonate-6-phosphate decarboxylase K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85]
D NPA10_02880 L-ribulose-5-phosphate 3-epimerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]
D NPA10_02875 araD; L-ribulose-5-phosphate 4-epimerase AraD K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]
C 00051 Fructose and mannose metabolism [PATH:mfd00051]
D NPA10_02260 fba; class II fructose-1,6-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D NPA10_00385 RpiB/LacA/LacB family sugar-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D NPA10_02240 fructose-specific PTS transporter subunit EIIC K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202]
C 00052 Galactose metabolism
D NPA10_04130 RpiB/LacA/LacB family sugar-phosphate isomerase K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26]
C 00053 Ascorbate and aldarate metabolism [PATH:mfd00053]
D NPA10_02870 PTS sugar transporter subunit IIB K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D NPA10_03605 PTS sugar transporter subunit IIB K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D NPA10_03620 PTS sugar transporter subunit IIB K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D NPA10_02900 3-dehydro-L-gulonate-6-phosphate decarboxylase K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85]
D NPA10_02880 L-ribulose-5-phosphate 3-epimerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]
D NPA10_02875 araD; L-ribulose-5-phosphate 4-epimerase AraD K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]
C 00500 Starch and sucrose metabolism [PATH:mfd00500]
D NPA10_04120 PTS lactose/cellobiose transporter subunit IIA K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D NPA10_04160 pgmB; beta-phosphoglucomutase K01838 pgmB; beta-phosphoglucomutase [EC:5.4.2.6]
D NPA10_00830 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
C 00620 Pyruvate metabolism [PATH:mfd00620]
D NPA10_03950 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D NPA10_03945 alpha-ketoacid dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D NPA10_03935 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D NPA10_00500 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D NPA10_03245 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:mfd00630]
D NPA10_00480 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D NPA10_03935 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00640 Propanoate metabolism [PATH:mfd00640]
D NPA10_00500 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D NPA10_03935 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00650 Butanoate metabolism
C 00660 C5-Branched dibasic acid metabolism
C 00562 Inositol phosphate metabolism [PATH:mfd00562]
D NPA10_02805 iolG; inositol 2-dehydrogenase K00010 iolG; myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase [EC:1.1.1.18 1.1.1.369]
D NPA10_02795 iolE; myo-inosose-2 dehydratase K03335 iolE; inosose dehydratase [EC:4.2.1.44]
D NPA10_02800 iolD; 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) K03336 iolD; 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) [EC:3.7.1.22]
D NPA10_02815 PfkB family carbohydrate kinase K03338 iolC; 5-dehydro-2-deoxygluconokinase [EC:2.7.1.92]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:mfd00190]
D NPA10_00240 atpA; F0F1 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D NPA10_00250 atpD; F0F1 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D NPA10_02940 F0F1 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D NPA10_00225 atpE; ATP synthase F0 subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D NPA10_00725 inorganic diphosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:mfd00710]
D NPA10_02775 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D NPA10_02770 gap; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D NPA10_02260 fba; class II fructose-1,6-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D NPA10_01775 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D NPA10_03630 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D NPA10_00385 RpiB/LacA/LacB family sugar-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
C 00720 Other carbon fixation pathways [PATH:mfd00720]
D NPA10_00840 bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D NPA10_00500 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
C 00680 Methane metabolism [PATH:mfd00680]
D NPA10_00480 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D NPA10_03255 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NPA10_02260 fba; class II fructose-1,6-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D NPA10_00500 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D NPA10_03305 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
C 00910 Nitrogen metabolism
C 00920 Sulfur metabolism
D NPA10_00045 bifunctional oligoribonuclease/PAP phosphatase NrnA K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation
C 00073 Cutin, suberine and wax biosynthesis
C 00074 Mycolic acid biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:mfd00561]
D NPA10_01465 glpK; glycerol kinase GlpK K00864 glpK; glycerol kinase [EC:2.7.1.30]
D NPA10_03130 plsX; phosphate acyltransferase PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
C 00564 Glycerophospholipid metabolism [PATH:mfd00564]
D NPA10_00460 glycerophosphodiester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
D NPA10_00280 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995 PGS1; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:mfd00230]
D NPA10_02560 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D NPA10_00565 adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D NPA10_03290 deoD; purine-nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]
D NPA10_00410 hpt; hypoxanthine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
D NPA10_01940 gmk; guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D NPA10_00290 nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D NPA10_00300 nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D NPA10_02555 RelA/SpoT family protein K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D NPA10_02735 TIGR00282 family metallophosphoesterase K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]
C 00240 Pyrimidine metabolism [PATH:mfd00240]
D NPA10_01475 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D NPA10_00435 upp; uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D NPA10_02735 TIGR00282 family metallophosphoesterase K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]
D NPA10_00290 nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D NPA10_00300 nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D NPA10_00155 thymidine phosphorylase K00758 deoA; thymidine phosphorylase [EC:2.4.2.4]
D NPA10_00590 thymidine kinase K00857 tdk; thymidine kinase [EC:2.7.1.21]
D NPA10_02625 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism
D NPA10_02545 aspartate--ammonia ligase K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1]
C 00260 Glycine, serine and threonine metabolism [PATH:mfd00260]
D NPA10_00480 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D NPA10_03305 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D NPA10_03935 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00270 Cysteine and methionine metabolism [PATH:mfd00270]
D NPA10_04065 metK; methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D NPA10_03480 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C 00280 Valine, leucine and isoleucine degradation [PATH:mfd00280]
D NPA10_03935 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00290 Valine, leucine and isoleucine biosynthesis
C 00300 Lysine biosynthesis
C 00310 Lysine degradation
D NPA10_03935 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00220 Arginine biosynthesis
C 00330 Arginine and proline metabolism
C 00340 Histidine metabolism
C 00350 Tyrosine metabolism
C 00360 Phenylalanine metabolism
C 00380 Tryptophan metabolism
D NPA10_03935 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism
C 00430 Taurine and hypotaurine metabolism
D NPA10_00500 acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:mfd00450]
D NPA10_01280 FAD-dependent oxidoreductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D NPA10_01600 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism [PATH:mfd00460]
D NPA10_02545 aspartate--ammonia ligase K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1]
D NPA10_00480 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism
C 00480 Glutathione metabolism [PATH:mfd00480]
D NPA10_03965 leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
B
B 09107 Glycan biosynthesis and metabolism
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:mfd00520]
D NPA10_04020 N-acetylmannosamine-6-phosphate 2-epimerase K01788 nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9]
D NPA10_02080 nagB; glucosamine-6-phosphate deaminase K02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6]
D NPA10_00830 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
C 00541 Biosynthesis of various nucleotide sugars
D NPA10_04025 N-acetylneuraminate lyase K01639 E4.1.3.3; N-acetylneuraminate lyase [EC:4.1.3.3]
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00550 Peptidoglycan biosynthesis
C 00552 Teichoic acid biosynthesis
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism
C 00740 Riboflavin metabolism
C 00750 Vitamin B6 metabolism
C 00760 Nicotinate and nicotinamide metabolism [PATH:mfd00760]
D NPA10_02120 nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D NPA10_03290 deoD; purine-nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]
C 00770 Pantothenate and CoA biosynthesis
C 00780 Biotin metabolism
C 00785 Lipoic acid metabolism [PATH:mfd00785]
D NPA10_03935 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D NPA10_03950 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D NPA10_03945 alpha-ketoacid dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
C 00790 Folate biosynthesis
C 00670 One carbon pool by folate [PATH:mfd00670]
D NPA10_00840 bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D NPA10_00480 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D NPA10_02625 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D NPA10_04065 metK; methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D NPA10_03935 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D NPA10_01775 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D NPA10_03630 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis
D NPA10_02805 iolG; inositol 2-dehydrogenase K00010 iolG; myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase [EC:1.1.1.18 1.1.1.369]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis
C 00401 Novobiocin biosynthesis
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
C 00333 Prodigiosin biosynthesis
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
C 00999 Biosynthesis of various plant secondary metabolites
D NPA10_04065 metK; methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation
C 00627 Aminobenzoate degradation
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:mfd03020]
D NPA10_03240 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D NPA10_03235 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D NPA10_01055 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
C 03022 Basal transcription factors
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:mfd03010]
D NPA10_02380 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D NPA10_01010 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D NPA10_03785 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D NPA10_00995 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D NPA10_03735 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D NPA10_00920 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D NPA10_01050 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D NPA10_03780 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D NPA10_01045 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D NPA10_00990 type Z 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D NPA10_00405 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D NPA10_02345 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D NPA10_00970 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D NPA10_02215 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D NPA10_00945 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D NPA10_00760 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D NPA10_00755 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D NPA10_02980 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D NPA10_00940 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D NPA10_00925 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D NPA10_00930 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D NPA10_00985 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D NPA10_01000 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D NPA10_03070 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D NPA10_02985 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D NPA10_03730 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D NPA10_00975 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D NPA10_01015 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D NPA10_00960 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D NPA10_01060 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D NPA10_01005 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D NPA10_02350 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D NPA10_02650 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D NPA10_03000 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D NPA10_00950 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D NPA10_00980 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D NPA10_02990 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D NPA10_02055 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D NPA10_01765 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D NPA10_00320 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D NPA10_02235 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D NPA10_03170 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D NPA10_04375 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D NPA10_02655 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D NPA10_01040 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
C 00970 Aminoacyl-tRNA biosynthesis [PATH:mfd00970]
D NPA10_04240 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D NPA10_00170 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D NPA10_00345 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D NPA10_02690 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D NPA10_01730 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D NPA10_02715 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D NPA10_02685 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D NPA10_01700 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D NPA10_01715 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D NPA10_03635 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D NPA10_03065 tRNA-His K14226 tRNA-His; tRNA His
D NPA10_00035 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D NPA10_04235 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D NPA10_01230 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D NPA10_01710 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D NPA10_01750 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D NPA10_01705 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D NPA10_02700 tRNA-Met K14230 tRNA-Met; tRNA Met
D NPA10_02710 tRNA-Met K14230 tRNA-Met; tRNA Met
D NPA10_02720 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D NPA10_02695 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D NPA10_02705 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D NPA10_02860 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D NPA10_03955 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D NPA10_01745 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D NPA10_04000 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D NPA10_02550 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D NPA10_01695 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D NPA10_01740 tRNA-Val K14237 tRNA-Val; tRNA Val
D NPA10_02865 tRNA-Trp K14238 tRNA-Sec; tRNA Sec
D NPA10_01245 gltX; glutamate--tRNA ligase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D NPA10_03025 amidase family protein K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D NPA10_01485 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D NPA10_00390 asnS; asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D NPA10_02445 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D NPA10_00395 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D NPA10_00075 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D NPA10_01600 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D NPA10_01145 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D NPA10_01495 class I tRNA ligase family protein K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D NPA10_02245 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D NPA10_01635 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D NPA10_04060 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D NPA10_02585 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D NPA10_03980 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:mfd03060]
D NPA10_01020 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D NPA10_01540 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D NPA10_04250 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D NPA10_02590 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D NPA10_00140 ffs; signal recognition particle sRNA small type K01983 ffs; SRP RNA
D NPA10_03085 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system
D NPA10_00805 mnmA; tRNA 2-thiouridine(34) synthase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
C 03050 Proteasome
C 03018 RNA degradation [PATH:mfd03018]
D NPA10_03255 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NPA10_01085 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
B
B 09124 Replication and repair
C 03030 DNA replication
C 03410 Base excision repair [PATH:mfd03410]
D NPA10_02300 mutM; DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D NPA10_01985 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
C 03420 Nucleotide excision repair [PATH:mfd03420]
D NPA10_01655 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
D NPA10_04255 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
C 03430 Mismatch repair
C 03440 Homologous recombination [PATH:mfd03440]
D NPA10_03670 recA; recombinase RecA K03553 recA; recombination protein RecA
D NPA10_02515 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
C 03450 Non-homologous end-joining
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus and Alphavirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03273 Virion - Lassa virus and SFTS virus
C 03272 Virion - Hepatitis viruses
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:mfd02010]
D NPA10_04090 ATP-binding cassette domain-containing protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11]
D NPA10_04345 ABC transporter ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D NPA10_00815 gguA; sugar ABC transporter ATP-binding protein K10548 gguA; putative multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D NPA10_01690 ABC transporter ATP-binding protein K23537 nupA; general nucleoside transport system ATP-binding protein
D NPA10_02835 sugar ABC transporter ATP-binding protein K10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]
D NPA10_03010 hypothetical protein K02042 phnE; phosphonate transport system permease protein
D NPA10_03005 ATP-binding cassette domain-containing protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D NPA10_01820 ABC transporter ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein
D NPA10_01625 ATP-binding cassette domain-containing protein K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
C 02060 Phosphotransferase system (PTS) [PATH:mfd02060]
D NPA10_00555 ptsP; phosphoenolpyruvate--protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D NPA10_00415 HPr family phosphocarrier protein K02784 ptsH; phosphocarrier protein HPr
D NPA10_04120 PTS lactose/cellobiose transporter subunit IIA K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D NPA10_02870 PTS sugar transporter subunit IIB K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D NPA10_03605 PTS sugar transporter subunit IIB K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D NPA10_03620 PTS sugar transporter subunit IIB K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D NPA10_02240 fructose-specific PTS transporter subunit EIIC K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202]
C 03070 Bacterial secretion system [PATH:mfd03070]
D NPA10_01540 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D NPA10_01020 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D NPA10_04250 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D NPA10_03085 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D NPA10_02590 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
B
B 09132 Signal transduction
C 02020 Two-component system
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04082 Neuroactive ligand signaling
C 04081 Hormone signaling
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
D NPA10_03015 superoxide dismutase K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:mfd02024]
D NPA10_01820 ABC transporter ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein
D NPA10_01540 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D NPA10_01020 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D NPA10_04250 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D NPA10_03085 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D NPA10_02590 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D NPA10_03255 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04981 Folate transport and metabolism [PATH:mfd04981]
D NPA10_00480 serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D NPA10_02625 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
C 04382 Cornified envelope formation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance
D NPA10_01820 ABC transporter ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein
C 01502 Vancomycin resistance
C 01503 Cationic antimicrobial peptide (CAMP) resistance
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:mfd01000]
C 01001 Protein kinases
C 01009 Protein phosphatases and associated proteins
C 01002 Peptidases and inhibitors [BR:mfd01002]
D NPA10_03965 leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D NPA10_00070 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D NPA10_01070 lon; endopeptidase La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
C 01003 Glycosyltransferases
C 01005 Lipopolysaccharide biosynthesis proteins
C 01011 Peptidoglycan biosynthesis and degradation proteins
C 01004 Lipid biosynthesis proteins [BR:mfd01004]
D NPA10_03130 plsX; phosphate acyltransferase PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases
C 01007 Amino acid related enzymes [BR:mfd01007]
D NPA10_01245 gltX; glutamate--tRNA ligase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D NPA10_02585 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D NPA10_03980 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D NPA10_01600 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D NPA10_02245 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D NPA10_01495 class I tRNA ligase family protein K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D NPA10_01635 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D NPA10_01485 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D NPA10_00390 asnS; asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D NPA10_02445 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D NPA10_00075 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D NPA10_00395 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D NPA10_04060 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:mfd00194]
D NPA10_00250 atpD; F0F1 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D NPA10_02940 F0F1 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D NPA10_00240 atpA; F0F1 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D NPA10_00225 atpE; ATP synthase F0 subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:mfd03000]
D NPA10_03480 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C 03021 Transcription machinery [BR:mfd03021]
D NPA10_01055 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D NPA10_03240 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D NPA10_03235 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D NPA10_00700 greA; transcription elongation factor GreA K03624 greA; transcription elongation factor GreA
C 03019 Messenger RNA biogenesis [BR:mfd03019]
D NPA10_03255 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NPA10_01085 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
C 03041 Spliceosome
C 03011 Ribosome [BR:mfd03011]
D NPA10_02380 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D NPA10_01010 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D NPA10_03785 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D NPA10_00995 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D NPA10_03735 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D NPA10_00920 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D NPA10_01050 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D NPA10_03780 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D NPA10_01045 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D NPA10_00990 type Z 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D NPA10_00405 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D NPA10_02345 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D NPA10_00970 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D NPA10_02215 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D NPA10_00945 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D NPA10_00760 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D NPA10_00755 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D NPA10_02980 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D NPA10_00940 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D NPA10_00925 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D NPA10_00930 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D NPA10_00985 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D NPA10_01000 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D NPA10_02985 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D NPA10_03070 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D NPA10_03730 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D NPA10_00975 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D NPA10_01015 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D NPA10_00960 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D NPA10_01060 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D NPA10_01005 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D NPA10_02350 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D NPA10_02650 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D NPA10_03000 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D NPA10_00950 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D NPA10_00980 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D NPA10_02990 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D NPA10_02055 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D NPA10_01765 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D NPA10_00320 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D NPA10_02235 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D NPA10_03170 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D NPA10_04375 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D NPA10_02655 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D NPA10_01040 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
C 03009 Ribosome biogenesis [BR:mfd03009]
D NPA10_03810 obgE; GTPase ObgE K03979 obgE; GTPase [EC:3.6.5.-]
D NPA10_01960 rsmH; 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D NPA10_03050 der; ribosome biogenesis GTPase Der K03977 engA; GTPase
D NPA10_02555 RelA/SpoT family protein K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D NPA10_00020 RNA-binding S4 domain-containing protein K14761 rlbA; ribosome-associated protein
D NPA10_00585 ychF; redox-regulated ATPase YchF K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:mfd03016]
D NPA10_02245 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D NPA10_01495 class I tRNA ligase family protein K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D NPA10_01600 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D NPA10_01635 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D NPA10_01485 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D NPA10_00390 asnS; asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D NPA10_02445 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D NPA10_00395 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D NPA10_00075 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D NPA10_04060 pheS; phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D NPA10_02585 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D NPA10_03980 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D NPA10_03690 mnmG; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D NPA10_01245 gltX; glutamate--tRNA ligase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D NPA10_02360 trmD; tRNA (guanosine(37)-N1)-methyltransferase TrmD K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D NPA10_00805 mnmA; tRNA 2-thiouridine(34) synthase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
C 03012 Translation factors [BR:mfd03012]
D NPA10_00780 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D NPA10_02340 tsf; translation elongation factor Ts K02357 tsf; elongation factor Ts
D NPA10_01575 tuf; elongation factor Tu K02358 tuf; elongation factor Tu
D NPA10_03790 fusA; elongation factor G K02355 fusA; elongation factor G
D NPA10_01760 prfA; peptide chain release factor 1 K02835 prfA; peptide chain release factor 1
D NPA10_00340 pth; aminoacyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D NPA10_01035 infA; translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1
D NPA10_02635 efp; elongation factor P K02356 efp; elongation factor P
C 03110 Chaperones and folding catalysts [BR:mfd03110]
D NPA10_00575 AAA family ATPase K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D NPA10_01085 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D NPA10_00070 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
C 04131 Membrane trafficking [BR:mfd04131]
D NPA10_02770 gap; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D NPA10_03245 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
C 04121 Ubiquitin system
C 03051 Proteasome
C 03032 DNA replication proteins [BR:mfd03032]
D NPA10_03480 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D NPA10_00030 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D NPA10_00025 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D NPA10_02130 type IIA DNA topoisomerase subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
C 03036 Chromosome and associated proteins [BR:mfd03036]
D NPA10_03480 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D NPA10_02130 type IIA DNA topoisomerase subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D NPA10_03690 mnmG; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
C 03400 DNA repair and recombination proteins [BR:mfd03400]
D NPA10_02300 mutM; DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D NPA10_01985 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D NPA10_01655 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
D NPA10_04255 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
D NPA10_03240 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D NPA10_03235 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D NPA10_01055 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D NPA10_03670 recA; recombinase RecA K03553 recA; recombination protein RecA
D NPA10_02515 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D NPA10_00030 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D NPA10_00025 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D NPA10_00290 nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D NPA10_00300 nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D NPA10_00045 bifunctional oligoribonuclease/PAP phosphatase NrnA K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
C 03029 Mitochondrial biogenesis [BR:mfd03029]
D NPA10_00780 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D NPA10_02340 tsf; translation elongation factor Ts K02357 tsf; elongation factor Ts
D NPA10_01575 tuf; elongation factor Tu K02358 tuf; elongation factor Tu
D NPA10_03790 fusA; elongation factor G K02355 fusA; elongation factor G
D NPA10_02585 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D NPA10_01495 class I tRNA ligase family protein K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D NPA10_01485 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D NPA10_02445 glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D NPA10_03025 amidase family protein K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D NPA10_01085 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:mfd02000]
D NPA10_04090 ATP-binding cassette domain-containing protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11]
D NPA10_04345 ABC transporter ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D NPA10_00815 gguA; sugar ABC transporter ATP-binding protein K10548 gguA; putative multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D NPA10_02835 sugar ABC transporter ATP-binding protein K10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]
D NPA10_01690 ABC transporter ATP-binding protein K23537 nupA; general nucleoside transport system ATP-binding protein
D NPA10_04355 carbohydrate ABC transporter permease K02026 ABC.MS.P1; multiple sugar transport system permease protein
D NPA10_03010 hypothetical protein K02042 phnE; phosphonate transport system permease protein
D NPA10_03005 ATP-binding cassette domain-containing protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D NPA10_01820 ABC transporter ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein
D NPA10_01625 ATP-binding cassette domain-containing protein K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D NPA10_03720 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D NPA10_03660 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D NPA10_00555 ptsP; phosphoenolpyruvate--protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D NPA10_00415 HPr family phosphocarrier protein K02784 ptsH; phosphocarrier protein HPr
D NPA10_02240 fructose-specific PTS transporter subunit EIIC K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202]
D NPA10_04120 PTS lactose/cellobiose transporter subunit IIA K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D NPA10_02870 PTS sugar transporter subunit IIB K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D NPA10_03605 PTS sugar transporter subunit IIB K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D NPA10_03620 PTS sugar transporter subunit IIB K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D NPA10_01470 aquaporin family protein K02440 glpF; glycerol uptake facilitator
C 02044 Secretion system [BR:mfd02044]
D NPA10_04250 secA; preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D NPA10_01540 secG; preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D NPA10_01020 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D NPA10_02590 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D NPA10_03085 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
C 02042 Bacterial toxins
C 02022 Two-component system
C 02035 Bacterial motility proteins
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins
C 04147 Exosome [BR:mfd04147]
D NPA10_03255 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D NPA10_02770 gap; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D NPA10_02775 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D NPA10_03245 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D NPA10_01085 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D NPA10_00830 glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D NPA10_01575 tuf; elongation factor Tu K02358 tuf; elongation factor Tu
D NPA10_00565 adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D NPA10_01465 glpK; glycerol kinase GlpK K00864 glpK; glycerol kinase [EC:2.7.1.30]
D NPA10_03935 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 02048 Prokaryotic defense system [BR:mfd02048]
D NPA10_01915 type I restriction-modification system subunit M K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D NPA10_03480 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D NPA10_02130 type IIA DNA topoisomerase subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:mfd03100]
D NPA10_04240 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D NPA10_00170 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D NPA10_00345 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D NPA10_02690 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D NPA10_01730 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D NPA10_02715 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D NPA10_02685 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D NPA10_01700 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D NPA10_01715 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D NPA10_03635 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D NPA10_03065 tRNA-His K14226 tRNA-His; tRNA His
D NPA10_00035 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D NPA10_04235 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D NPA10_01230 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D NPA10_01710 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D NPA10_01750 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D NPA10_01705 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D NPA10_02700 tRNA-Met K14230 tRNA-Met; tRNA Met
D NPA10_02710 tRNA-Met K14230 tRNA-Met; tRNA Met
D NPA10_02720 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D NPA10_02695 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D NPA10_02705 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D NPA10_02860 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D NPA10_03955 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D NPA10_01745 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D NPA10_04000 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D NPA10_02550 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D NPA10_01695 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D NPA10_01740 tRNA-Val K14237 tRNA-Val; tRNA Val
D NPA10_02865 tRNA-Trp K14238 tRNA-Sec; tRNA Sec
D NPA10_00140 ffs; signal recognition particle sRNA small type K01983 ffs; SRP RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D NPA10_03035 msrA; peptide-methionine (S)-S-oxide reductase MsrA K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D NPA10_03745 ferritin K02217 ftnA; ferritin [EC:1.16.3.2]
D NPA10_00270 diadenylate cyclase K18672 dacA; diadenylate cyclase [EC:2.7.7.85]
D NPA10_01270 hprK; HPr(Ser) kinase/phosphatase K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-]
D NPA10_02895 phosphotriesterase K23149 E3.1.1.104; 5-phospho-D-xylono-1,4-lactonase [EC:3.1.1.104]
D NPA10_04315 TatD family hydrolase K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D NPA10_02565 rnmV; ribonuclease M5 K05985 rnmV; ribonuclease M5 [EC:3.1.26.8]
D NPA10_02500 hypothetical protein K24914 lanKC; class III lanthionine synthetase [EC:3.13.2.4]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
D NPA10_00295 nrdI; class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI K03647 nrdI; protein involved in ribonucleotide reduction
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
C 99987 Cofactor metabolism
C 99988 Secondary metabolism
C 99999 Others
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
C 99974 Translation
C 99975 Protein processing
D NPA10_01550 smpB; SsrA-binding protein SmpB K03664 smpB; SsrA-binding protein
C 99976 Replication and repair
C 99979 Viral proteins
C 99998 Others
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
C 99978 Cell growth
C 99993 Cell motility
C 99995 Signaling proteins
C 99992 Structural proteins
C 99994 Others
B
B 09194 Poorly characterized
C 99996 General function prediction only
C 99997 Function unknown
D NPA10_02155 YneF family protein K09976 K09976; uncharacterized protein
!
#
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: June 25, 2025