+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Methanocaldococcus fervens</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
D      Cap binding complex
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
D      Pre-mRNA cleavage factor IIm (CFIIm)
D      Cleavage and polyadenylation specificity factor (CPSF) complex
D      Cleavage stimulation factor (CSTF) complex
D      U7-dependent histone pre-mRNA processing factors
D      DRB sensitivity inducing factor (DSIF) complex
E        Mefer_0873 DNA-directed RNA polymerase subunit E, RpoE2	K15171 SUPT4H1; transcription elongation factor SPT4 
E        Mefer_1447 NusG antitermination factor	K15172 SUPT5H; transcription elongation factor SPT5 
D      N6-methyltransferase complex
D      Poly(A) addition factors
D      Negative regulators of mRNA 3' end processing
C    Other processing factors
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
D      TREX complex
D      TREX-2 complex
D      Nuclear pore complex
D      Ran-mediated transport factors
E        Mefer_0752 AAA family ATPase, CDC48 subfamily	K13525 VCP; transitional endoplasmic reticulum ATPase 
D      eIF4F and regulatory proteins
D      APOBEC1-ACF complex
D      Other transport factors
E        Mefer_0742 translation factor pelota	K06965 PELO; protein pelota 
C    Surveillance factors
D      Surveillance complex
E        Mefer_0919 eRF1 domain 2 protein	K03265 ETF1; peptide chain release factor subunit 1 
D      Protein phosphatase 2A
D      Other surveillance factors
C    Factors involved in mRNA localization
D      Cargo complex
D      Factors that have mRNA localization signals
D      Trans-acting binding proteins
E        Mefer_1271 translation elongation factor EF-1, subunit alpha	K03231 EEF1A; elongation factor 1-alpha 
D      Other mRNA localization factors
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
D      P-body specific factors
D      Stress granule specific factors
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
D      Lsm complex
D      5' exonucleases
D      Other 5'-3' decay factors
C    3'-5' decay
D      Core exosome factors
D      Exosome cofactors
D      TRAMP complex
D      Ski complex
D      Ccr4-NOT complex
D      Pan complex
D      Other 3'-5' decay factors
C    Other degradation factors
D      RNases
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A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        Mefer_1121 beta-lactamase domain protein	K12574 rnj; ribonuclease J [EC:3.1.-.-] 
D      Helicases
E        Mefer_1401 DEAD/DEAH box helicase domain protein	K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] 
D      Other RNA degradosome components
E        Mefer_0447 enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        Mefer_0181 Uncharacterized host factor I protein-like protein	K03666 hfq; host factor-I protein 
D      Others
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
D      Cofactors
D      Others
E        Mefer_0598 DEAD/DEAH box helicase domain protein	K03725 K03725; putative ATP-dependent RNA helicase [EC:5.6.2.-] 
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#Last updated: April 25, 2024