+C Lipid biosynthesis protein KO
#
Lipid Biosynthesis Proteins - Mycolicibacterium farcinogenes
%
!
AFatty acid synthase
B Animal type
B Yeast type
B Bacteria type
C K6L26_11430 type I polyketide synthase K11533 fas; fatty acid synthase, bacteria type [EC:2.3.1.-]
B Component type
C K6L26_13140 ACP S-malonyltransferase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
C K6L26_25710 malonyl CoA-ACP transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
C K6L26_04140 hypothetical protein K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
C K6L26_25200 3-oxoacyl-ACP synthase K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
C K6L26_10950 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C K6L26_11020 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C K6L26_12930 3-oxoacyl-ACP reductase FabG K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C K6L26_21755 fabG; 3-oxoacyl-ACP reductase FabG K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C K6L26_22565 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C K6L26_27720 SDR family NAD(P)-dependent oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C K6L26_29905 3-oxoacyl-ACP reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C K6L26_30250 fabG; 3-oxoacyl-ACP reductase FabG K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C K6L26_14605 thioesterase family protein K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C K6L26_17290 acyl-CoA thioesterase II K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C K6L26_18780 tesB; acyl-CoA thioesterase II K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C K6L26_20525 thioesterase family protein K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C K6L26_13130 beta-ketoacyl-ACP synthase K11609 kasA; meromycolic acid 3-oxoacyl-[acyl-carrier protein] synthase I [EC:2.3.1.293]
C K6L26_13125 beta-ketoacyl-ACP synthase K27070 kasB; meromycolic acid 3-oxoacyl-[acyl-carrier protein] synthase II [EC:2.3.1.294]
C K6L26_26205 beta-ketoacyl-ACP synthase K27070 kasB; meromycolic acid 3-oxoacyl-[acyl-carrier protein] synthase II [EC:2.3.1.294]
C K6L26_17725 beta-ketoacyl-ACP reductase K11610 mabA; meromycolic acid 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.-]
C K6L26_25820 hadA; (3R)-hydroxyacyl-ACP dehydratase subunit HadA K27071 hadA; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadA [EC:4.2.1.-]
C K6L26_25815 hadB; (3R)-hydroxyacyl-ACP dehydratase subunit HadB K27072 hadB; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadB [EC:4.2.1.-]
C K6L26_01765 MaoC family dehydratase N-terminal domain-containing protein K27689 hadAB; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadAB [EC:4.2.1.-]
C K6L26_25810 hadC; (3R)-hydroxyacyl-ACP dehydratase subunit HadC K27073 hadC; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadC [EC:4.2.1.-]
C K6L26_26860 MaoC family dehydratase N-terminal domain-containing protein K27074 hadD; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadD [EC:4.2.1.-]
C K6L26_17720 fabI; enoyl-ACP reductase FabI K11611 inhA; meromycolic acid enoyl-[acyl-carrier protein] reductase [EC:1.3.1.118]
#
ADesaturase
B First
C K6L26_03090 acyl-ACP desaturase K03921 FAB2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]
C K6L26_06460 acyl-ACP desaturase K03921 FAB2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]
C K6L26_16740 acyl-ACP desaturase K03921 FAB2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]
C K6L26_08940 acyl-ACP desaturase K03922 desA2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.-]
C K6L26_22990 fatty acid desaturase K22769 desA3; NADPH-dependent stearoyl-CoA 9-desaturase [EC:1.14.19.-]
C K6L26_23705 acyl-CoA desaturase K22769 desA3; NADPH-dependent stearoyl-CoA 9-desaturase [EC:1.14.19.-]
B Omega
B Front-end
B Sphingolipid
B Other
#
AElongase
B LCFA
B PUFA
B Unclassified
#
APolyketide synthase
B Modular PKS
C K6L26_02910 type I polyketide synthase K12437 pks13; polyketide synthase 13
B Component type
C K6L26_12520 polyketide synthase K04790 mbtC; mycobactin polyketide synthetase MbtC
C K6L26_12525 mbtD; mycobactin polyketide synthase MbtD K04791 mbtD; mycobactin polyketide synthetase MbtD
#
AAcyl-CoA ligase
B Short/medium chain acyl-CoA ligase
C K6L26_04540 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C K6L26_07015 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C K6L26_08315 propionyl-CoA synthetase K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17]
C K6L26_05455 acetoacetate--CoA ligase K01907 AACS; acetoacetyl-CoA synthetase [EC:6.2.1.16]
C K6L26_11385 AMP-binding protein K12507 fadK; acyl-CoA synthetase [EC:6.2.1.-]
C K6L26_11780 acyl--CoA ligase K12507 fadK; acyl-CoA synthetase [EC:6.2.1.-]
B Long/very long chain acyl-CoA ligase
C K6L26_13505 long-chain fatty acid--CoA ligase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C K6L26_21770 fatty acid--CoA ligase family protein K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C K6L26_14785 acyl-CoA synthetase K03822 K03822; putative long chain acyl-CoA synthase [EC:6.2.1.-]
C K6L26_09595 acyl-CoA synthetase K12429 fadD36; fatty acid CoA ligase FadD36
B Unknown
C K6L26_18700 carboxylic acid reductase K12421 fadD9; fatty acid CoA ligase FadD9
C K6L26_18705 carboxylic acid reductase K12421 fadD9; fatty acid CoA ligase FadD9
C K6L26_29815 AMP-binding protein K12423 fadD21; fatty acid CoA ligase FadD21
C K6L26_00480 fadD5; fatty-acid--CoA ligase FadD5 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C K6L26_05205 fatty acyl-AMP ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C K6L26_05885 fadD17; long-chain-fatty-acid--CoA ligase FadD17 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C K6L26_07020 AMP-binding protein K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C K6L26_07175 long-chain fatty acid--CoA ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C K6L26_08125 fatty acyl-AMP ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C K6L26_09650 fadD6; long-chain-acyl-CoA synthetase FadD6 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C K6L26_10390 fadD1; fatty-acid--CoA ligase FadD1 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C K6L26_16070 AMP-binding protein K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C K6L26_19295 AMP-binding protein K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C K6L26_26580 fadD8; fatty-acid--CoA ligase FadD8 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C K6L26_27730 acyl-CoA synthetase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
#
AAcyl-AMP ligase
B Fatty acyl-AMP ligase (FAAL)
C K6L26_11650 fadD10; fatty acid--CoA ligase FadD10 K12422 fadD10; medium/long-chain-fatty-acid---[acyl-carrier-protein] ligase FadD10 [EC:6.2.1.-]
C K6L26_05725 AMP-binding protein K12427 fadD28; long-chain fatty acid adenylyltransferase FadD28 [EC:6.2.1.49]
C K6L26_02905 fadD32; fadD32 K12428 fadD32; fatty acyl-AMP ligase FadD32 [EC:6.2.1.-]
B Aryl-AMP ligase
#
APhospholipid acyltransferase
B GPAT
C K6L26_11820 glycerol-3-phosphate 1-O-acyltransferase K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
B LPAAT/LPLAT
C K6L26_13530 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
#
AOthers
B Multifunctional type
C K6L26_05720 type I polyketide synthase K12433 pks5; polyketide synthase 5
C K6L26_17665 type I polyketide synthase K12433 pks5; polyketide synthase 5
B Component type
!
#
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: December 11, 2024
#
Desaturase/elongase family classification based on Hashimoto et al. (2008)