+C Two-component system KO
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Two-Component System - Mycolicibacterium fortuitum
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
B SenX3-RegX3 (phosphate starvation response)
C XA26_52170 PhoR-like protein K07768 senX3; two-component system, OmpR family, sensor histidine kinase SenX3 [EC:2.7.13.3]
C XA26_52160 SphR-like protein K07776 regX3; two-component system, OmpR family, response regulator RegX3
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
C XA26_48060 Osmosensitive K+ channel histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C XA26_48070 kdpE; KdpE K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
C XA26_49170 Osmosensitive K+ channel histidine kinase KdpD K07653 mprB; two-component system, OmpR family, sensor histidine kinase MprB [EC:2.7.13.3]
C XA26_49180 Two-component response regulator K07669 mprA; two-component system, OmpR family, response regulator MprA
B MtrB-MtrA (osmotic stress response)
C XA26_18910 Sensor histidine kinase MtrB K07654 mtrB; two-component system, OmpR family, sensor histidine kinase MtrB [EC:2.7.13.3]
C XA26_18900 DNA-binding response regulator mtrA K07670 mtrA; two-component system, OmpR family, response regulator MtrA
B PrrB-PrrA (intracellular multiplication)
C XA26_12090 Sensor-type histidine kinase prrB K07655 prrB; two-component system, OmpR family, sensor histidine kinase PrrB [EC:2.7.13.3]
C XA26_27070 sensor histidine kinase K07655 prrB; two-component system, OmpR family, sensor histidine kinase PrrB [EC:2.7.13.3]
C XA26_01960 sensor histidine kinase K07655 prrB; two-component system, OmpR family, sensor histidine kinase PrrB [EC:2.7.13.3]
C XA26_12100 DNA-binding response regulator K07671 prrA; two-component system, OmpR family, response regulator PrrA
C XA26_01940 TrcR-like protein K07671 prrA; two-component system, OmpR family, response regulator PrrA
B TrcS-TrcR
C XA26_51020 Two-component system, sensor protein K07656 trcS; two-component system, OmpR family, sensor histidine kinase TrcS [EC:2.7.13.3]
C XA26_51030 TrcR-like protein K07672 trcR; two-component system, OmpR family, response regulator TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C XA26_43980 sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C XA26_09760 PhoR-like protein K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C XA26_43990 putative two-component system response regulator K02483 K02483; two-component system, OmpR family, response regulator
C XA26_09750 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
C XA26_00930 DNA-binding response regulator, LuxR family protein K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
C XA26_46760 devS; DevS K07682 devS; two-component system, NarL family, sensor histidine kinase DevS [EC:2.7.13.3]
C XA26_46780 devR; DevR K07695 devR; two-component system, NarL family, response regulator DevR
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
C XA26_00940 hypothetical protein K02480 K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3]
C XA26_09280 sensor kinase, two-component system K02480 K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3]
C XA26_14920 Sensor histidine protein kinase UhpB, glucose-6-phosphate specific K02480 K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3]
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
C XA26_36610 Signal transduction histidine kinase CitA regulating citrate metabolism K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3]
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
C XA26_45880 lytS; LytS K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
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ACheA family
B CheA-CheYBV (chemotaxis)
C XA26_13460 Protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C XA26_13440 Chemotaxis protein methyltransferase CheR K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61]
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
B PdtaS-PdtaR
C XA26_19240 Signal transduction histidine kinase, subgroup 2 K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]
C XA26_31050 response regulator K22010 pdtaR; two-component system, response regulator PdtaR
B NasS-NasT
B Unclassified
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023