+E Polyketide biosynthesis proteins KO
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Polyketide Biosynthesis Proteins - Mycolicibacter heraklionensis
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APolyketide synthase (PKS)
B Modular type I PKS
C cis-AT PKS
D Erythronolide PKS
D Oleandomycin synthase
D Pikromycin PKS
D Avermectin PKS
D Tylactone synthase
D Protomycinolide IV synthase
D Niddamycin PKS
D Rapamycin PKS
D Immunomycin PKS
D Ansamitocin PKS
D Rifamycin PKS
D Polyene macrolide PKS
D Pimaricinolide synthase
D Candicidin PKS
D Soraphen PKS
D Stigmatellin PKS
D Mycolactone PKS
D Coelimycin PKS
D Aureothin PKS
D Spectinabilin PKS
D Phthiocerol / Phenolphthiocerol PKS
E K3U94_12460 acyltransferase domain-containing protein K12440 ppsA; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase A [EC:2.3.1.292]
E K3U94_12455 SDR family NAD(P)-dependent oxidoreductase K12441 ppsB; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase B [EC:2.3.1.292]
E K3U94_12445 type I polyketide synthase K12443 ppsD; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase D [EC:2.3.1.292]
E K3U94_12450 SDR family NAD(P)-dependent oxidoreductase K12443 ppsD; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase D [EC:2.3.1.292]
E K3U94_12440 acyltransferase domain-containing protein K12444 ppsE; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase E [EC:2.3.1.292]
C trans-AT PKS
D Bacillanene hybrid PKS-NRPS
E K3U94_23110 PfaD family polyunsaturated fatty acid/polyketide biosynthesis protein K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains
D Chivosazol hybrid PKS-NRPS
E K3U94_23110 PfaD family polyunsaturated fatty acid/polyketide biosynthesis protein K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains
E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133]
D Macrolactin PKS
E K3U94_23110 PfaD family polyunsaturated fatty acid/polyketide biosynthesis protein K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains
D Difficidin PKS
E K3U94_23110 PfaD family polyunsaturated fatty acid/polyketide biosynthesis protein K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains
D Rhizoxin hybrid PKS-NRPS
D Myxovirescin hybrid PKS-NRPS
E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932]
D Albicidin synthase, hybrid PKS-NRPS
E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516]
E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523]
D Etnangien PKS
E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193]
B Iterative type I PKS
C Fungal nonreducing PKS (NR-PKS)
C Fungal partially reducing PKS (PR-PKS)
C Fungal highly reducing PKS (HR-PKS)
C Fungal hybrid type
D Zearalenone synthase
D Asperfuranone NR/HR-PKS
E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:AN1034.2]
E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:AN1036.2]
C Bacterial type
B Type II PKS
C C9-C14 cyclized polyketide type
D Spore pigment PKS
C C7-C14 cyclized polyketide type
D Octaketide PKS
D Nonaketide PKS
D Decaketide PKS
B Type III PKS
C Plant type
C Fungal type
C Bacterial type
D K3U94_18750 type III polyketide synthase K16167 bpsA; alkylresorcinol/alkylpyrone synthase
D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550]
D ------ arsC; alkylpyrone synthase [AVN:Avin_29530]
B PKS-NRPS hybrid
C Bacterial type (modular)
D Myxalamid hybrid PKS-NRPS
D Myxothiazol hybrid PKS-NRPS
E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019]
D Coronatine hybrid PKS-NRPS
D Microcystin synthetase
D Epothilone synthetase
D Bleomycin synthetase
D Colibactin synthetase
C Fungal type (trans-ER, iterative)
D Aspyridone synthetase
C Fungal type (iterative)
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ANonribosomal peptide synthetase (NRPS)
B Linear NRPS
C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:AN2545.2]
C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500]
C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000]
C ACV synthetase
C Bacitracin synthetase
C Viomycin synthetase
C Pristinamycin I synthetase
C Tyrocidine synthetase
C Surfactin family lipopeptide synthetase
C Iturin family lipopeptide synthetase
C Fengycin family lipopeptide synthetase
C Arthrofactin type cyclic lipopeptide synthetase
C Vancomycin synthetase
C Nocardicin synthetase
D K3U94_08470 MbtH family protein K05375 mbtH; MbtH protein
C Bialaphos synthetase
C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase
B Iterative NRPS
C Enterobactin synthetase
C Bacillibactin synthetase
C Gramicidin synthetase
B Nonlinear NRPS
C Yersiniabactin synthetase
C Pyochelin synthetase
C Mycobactin synthetase
D K3U94_08415 AMP-binding protein K04787 mbtA; mycobactin salicyl-AMP ligase [EC:6.3.2.-]
D K3U94_08420 amino acid adenylation domain-containing protein K04788 mbtB; mycobactin phenyloxazoline synthetase
D K3U94_08445 polyketide synthase K04790 mbtC; mycobactin polyketide synthetase MbtC
D K3U94_08450 SDR family NAD(P)-dependent oxidoreductase K04791 mbtD; mycobactin polyketide synthetase MbtD
D K3U94_08455 amino acid adenylation domain-containing protein K04789 mbtE; mycobactin peptide synthetase MbtE
D K3U94_08460 amino acid adenylation domain-containing protein K04792 mbtF; mycobactin peptide synthetase MbtF
C Vibriobactin synthetase
C Myxochelin synthetase
C Petrobacin synthetase
C Syringomycin synthetase
C Vanchrobactin synthetase
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APolyketide tailoring proteins
B Hydrolase
B Ketoreductase
B Oxygenase
B Methylase
C K3U94_18755 isoprenylcysteine carboxyl methyltransferase family protein K16168 bpsB; methyltransferase
B Glycosyltransferase
B Halogenase
B beta-Branched incorporating proteins
B Others
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ANonribosomal peptide tailoring proteins
B Reductase
B Thioesterase
B Oxygenase
C K3U94_08465 mbtG; NADPH-dependent L-lysine N(6)-monooxygenase MbtG K04793 mbtG; mycobactin lysine-N-oxygenase
B Glycosyltransferase
B Aminotransferase
B Others
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#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: February 19, 2024