+C Lipid biosynthesis protein KO
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Lipid Biosynthesis Proteins - Mycolicibacter hiberniae
%
!
AFatty acid synthase
B Animal type
B Yeast type
B Bacteria type
C MHIB_08370 type I polyketide synthase K11533 fas; fatty acid synthase, bacteria type [EC:2.3.1.-]
B Component type
C MHIB_10860 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
C MHIB_01310 3-oxoacyl-ACP synthase K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
C MHIB_13650 fabG_2; 3-oxoacyl-[acyl-carrier-protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MHIB_28090 short-chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MHIB_29980 putative short chain dehydrogenase/reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MHIB_31040 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MHIB_32920 fabG4; 3-oxoacyl-ACP reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MHIB_40620 short-chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C MHIB_14970 putative 2-nitropropane dioxygenase, NPD K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
C MHIB_00820 tesB; acyl-CoA thioesterase II K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C MHIB_15860 tesB1; acyl-CoA thioesterase II K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C MHIB_18440 tesB2; acyl-CoA thioesterase II K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C MHIB_33940 acyl-CoA thioesterase II K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C MHIB_35390 acyl-CoA thioesterase II K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C MHIB_37170 acyl-CoA thioesterase II K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
C MHIB_39220 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase 3 K11608 mtfabH; mycobacterial beta-ketoacyl-[acyl-carrier protein] synthase III [EC:2.3.1.301]
C MHIB_10840 kasA; 3-oxoacyl-[acyl-carrier-protein] synthase 1 K11609 kasA; meromycolic acid 3-oxoacyl-[acyl-carrier protein] synthase I [EC:2.3.1.293]
C MHIB_10830 kasB; 3-oxoacyl-[acyl-carrier-protein] synthase 2 K27070 kasB; meromycolic acid 3-oxoacyl-[acyl-carrier protein] synthase II [EC:2.3.1.294]
C MHIB_26020 3-oxoacyl-ACP synthase K27070 kasB; meromycolic acid 3-oxoacyl-[acyl-carrier protein] synthase II [EC:2.3.1.294]
C MHIB_16790 fabG_3; 3-oxoacyl-[acyl-carrier-protein] reductase FabG K11610 mabA; meromycolic acid 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.-]
C MHIB_01730 UPF0336 protein K27071 hadA; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadA [EC:4.2.1.-]
C MHIB_01740 hadB; (3R)-hydroxyacyl-ACP dehydratase subunit HadB K27072 hadB; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadB [EC:4.2.1.-]
C MHIB_35270 (R)-hydratase K27689 hadAB; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadAB [EC:4.2.1.-]
C MHIB_01750 UPF0336 protein K27073 hadC; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadC [EC:4.2.1.-]
C MHIB_40250 UPF0336 protein K27074 hadD; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadD [EC:4.2.1.-]
C MHIB_16780 inhA; enoyl-[acyl-carrier-protein] reductase [NADH] K11611 inhA; meromycolic acid enoyl-[acyl-carrier protein] reductase [EC:1.3.1.118]
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ADesaturase
B First
C MHIB_03640 putative acyl-[acyl-carrier protein] desaturase K03921 FAB2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]
C MHIB_29230 acyl-ACP desaturase K03921 FAB2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]
C MHIB_05990 desA2; putative acyl-[acyl-carrier-protein] desaturase DesA2 K03922 desA2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.-]
C MHIB_03560 desA3_1; NADPH-dependent stearoyl-CoA 9-desaturase K22769 desA3; NADPH-dependent stearoyl-CoA 9-desaturase [EC:1.14.19.-]
C MHIB_23730 desA3_2; NADPH-dependent stearoyl-CoA 9-desaturase K22769 desA3; NADPH-dependent stearoyl-CoA 9-desaturase [EC:1.14.19.-]
C MHIB_34200 fatty acid desaturase K22769 desA3; NADPH-dependent stearoyl-CoA 9-desaturase [EC:1.14.19.-]
B Omega
B Front-end
B Sphingolipid
B Other
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AElongase
B LCFA
B PUFA
B Unclassified
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APolyketide synthase
B Modular PKS
C MHIB_34400 polyketide synthase K12437 pks13; polyketide synthase 13
C MHIB_16640 hypothetical protein K12440 ppsA; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase A [EC:2.3.1.292]
C MHIB_16620 ppsB; phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsB K12441 ppsB; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase B [EC:2.3.1.292]
C MHIB_16600 ppsD; phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsD K12443 ppsD; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase D [EC:2.3.1.292]
C MHIB_16610 hypothetical protein K12443 ppsD; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase D [EC:2.3.1.292]
C MHIB_16590 ppsE; phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsE K12444 ppsE; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase E [EC:2.3.1.292]
B Component type
C MHIB_09930 polyketide synthase K04790 mbtC; mycobactin polyketide synthetase MbtC
C MHIB_09940 mbtD; polyketide synthase K04791 mbtD; mycobactin polyketide synthetase MbtD
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AAcyl-CoA ligase
B Short/medium chain acyl-CoA ligase
C MHIB_32080 hypothetical protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C MHIB_10620 AMP-dependent synthetase K12507 fadK; acyl-CoA synthetase [EC:6.2.1.-]
C MHIB_28330 long-chain-fatty-acid--CoA ligase K12507 fadK; acyl-CoA synthetase [EC:6.2.1.-]
B Long/very long chain acyl-CoA ligase
C MHIB_00860 acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C MHIB_01040 fadD4; fatty-acid--CoA ligase FadD4 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C MHIB_11610 fadD15; long-chain-fatty-acid--CoA ligase FadD15 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C MHIB_27080 fadD; long-chain acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C MHIB_29140 acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C MHIB_40960 hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C MHIB_12930 acyl-CoA synthetase K03822 K03822; putative long chain acyl-CoA synthase [EC:6.2.1.-]
C MHIB_06900 fadD36; acyl-CoA synthetase K12429 fadD36; fatty acid CoA ligase FadD36
B Unknown
C MHIB_35060 fadD9; acyl-CoA synthetase K12421 fadD9; fatty acid CoA ligase FadD9
C MHIB_35820 fadD21; putative fatty-acid--CoA ligase fadD21 K12423 fadD21; fatty acid CoA ligase FadD21
C MHIB_02300 AMP-dependent synthetase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MHIB_03440 putative fatty-acid-CoA ligase FadD K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MHIB_04710 putative ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MHIB_06960 fadD6; long-chain-acyl-CoA synthetase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MHIB_10960 acyl-CoA synthetase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MHIB_14780 fadD31; nitrate ABC transporter substrate-binding protein K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MHIB_23930 acyl-CoA synthetase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MHIB_30400 acyl-CoA synthetase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MHIB_33820 fadD5; fatty-acid--CoA ligase FadD5 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C MHIB_36560 putative fatty-acid-CoA ligase FadD K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
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AAcyl-AMP ligase
B Fatty acyl-AMP ligase (FAAL)
C MHIB_16650 fadD26_1; long-chain-fatty-acid--AMP ligase FadD26 K12426 fadD26; long-chain fatty acid adenylase/transferase FadD26 [EC:6.2.1.59]
C MHIB_20260 fadD26_2; long-chain-fatty-acid--AMP ligase FadD26 K12426 fadD26; long-chain fatty acid adenylase/transferase FadD26 [EC:6.2.1.59]
C MHIB_34410 fadD32; long-chain-fatty-acid--AMP ligase FadD32 K12428 fadD32; fatty acyl-AMP ligase FadD32 [EC:6.2.1.-]
B Aryl-AMP ligase
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APhospholipid acyltransferase
B GPAT
C MHIB_08780 plsB; glycerol-3-phosphate acyltransferase K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
B LPAAT/LPLAT
C MHIB_11660 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
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AOthers
B Multifunctional type
C MHIB_35870 pks3; polyketide synthase K12432 pks3_4; mycolipanoate synthase [EC:2.3.1.252]
B Component type
!
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#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: June 25, 2024
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Desaturase/elongase family classification based on Hashimoto et al. (2008)