+D GENES KO #

  KEGG Orthology (KO) - Metallosphaera hakonensis JCM 8857 = DSM 7519

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A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:mhk00010] D DFR87_08095 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D DFR87_09415 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D DFR87_05680 aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D DFR87_06780 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D DFR87_11485 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D DFR87_10480 phosphorylating glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] D DFR87_10485 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D DFR87_03560 histidine phosphatase family protein K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D DFR87_07345 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D DFR87_10335 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D DFR87_11830 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D DFR87_04040 pyruvate, water dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D DFR87_10200 ppsA; pyruvate, water dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D DFR87_01520 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_10985 FAD-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08450 NAD(P)-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08650 FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_04615 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_05210 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_04620 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05205 3-methyl-2-oxobutanoate dehydrogenase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05220 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04605 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04610 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D DFR87_05215 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D DFR87_04800 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D DFR87_04795 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D DFR87_12270 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_12345 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_05465 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_11685 CoA-binding protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D DFR87_11455 aldose 1-epimerase K01785 galM; aldose 1-epimerase [EC:5.1.3.3] D DFR87_05590 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D DFR87_12305 aldehyde dehydrogenase family protein K18978 gapN; glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] [EC:1.2.1.90] D DFR87_11480 phosphoenolpyruvate carboxykinase (GTP) K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] C 00020 Citrate cycle (TCA cycle) [PATH:mhk00020] D DFR87_11115 citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1] D DFR87_05395 citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1] D DFR87_11400 acnA; aconitate hydratase AcnA K01681 ACO; aconitate hydratase [EC:4.2.1.3] D DFR87_03270 NADP-dependent isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D DFR87_01520 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_10985 FAD-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08450 NAD(P)-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08650 FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_04800 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D DFR87_04795 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D DFR87_10785 sucD; succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D DFR87_10790 succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D DFR87_03130 succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D DFR87_12140 FAD-binding protein K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D DFR87_03125 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D DFR87_12155 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D DFR87_03120 disulfide reductase K00241 sdhC; succinate dehydrogenase cytochrome b subunit D DFR87_12145 succinate dehydrogenase K00241 sdhC; succinate dehydrogenase cytochrome b subunit D DFR87_12150 succinate dehydrogenase K00242 sdhD; succinate dehydrogenase membrane anchor subunit D DFR87_03115 succinate dehydrogenase K18859 sdhD; succinate dehydrogenase subunit D D DFR87_12130 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D DFR87_12135 Fe-S hydro-lyase subunit beta K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D DFR87_11430 fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D DFR87_03910 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D DFR87_11480 phosphoenolpyruvate carboxykinase (GTP) K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] D DFR87_04615 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_05210 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_04620 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05205 3-methyl-2-oxobutanoate dehydrogenase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05220 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04605 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04610 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D DFR87_05215 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] C 00030 Pentose phosphate pathway [PATH:mhk00030] D DFR87_08095 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D DFR87_09415 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D DFR87_09140 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D DFR87_09145 transketolase family protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D DFR87_06915 rpiA; ribose 5-phosphate isomerase A K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D DFR87_05610 D-arabino 3-hexulose 6-phosphate aldehyde lyase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43] D DFR87_05675 hxlB; 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D DFR87_03780 carbohydrate kinase family protein K00852 rbsK; ribokinase [EC:2.7.1.15] D DFR87_05895 ribokinase K00852 rbsK; ribokinase [EC:2.7.1.15] D DFR87_05590 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D DFR87_09685 prs; ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D DFR87_12295 2-dehydro-3-deoxyphosphogluconate aldolase K11395 kdpgA; 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase [EC:4.1.2.55] D DFR87_12305 aldehyde dehydrogenase family protein K18978 gapN; glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] [EC:1.2.1.90] D DFR87_11970 alcohol dehydrogenase catalytic domain-containing protein K18125 ssgdh; aldose 1-dehydrogenase [NAD(P)+] [EC:1.1.1.359] D DFR87_11980 mandelate racemase/muconate lactonizing enzyme family protein K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140] D DFR87_12300 sugar kinase K18126 sskdgK; 2-dehydro-3-deoxygluconokinase / 2-dehydro-3-deoxygalactonokinase [EC:2.7.1.178] D DFR87_05315 molybdopterin-dependent oxidoreductase K18020 cutA; glyceraldehyde dehydrogenase large subunit [EC:1.2.99.8] D DFR87_05305 xanthine dehydrogenase family protein subunit M K18021 cutB; glyceraldehyde dehydrogenase medium subunit [EC:1.2.99.8] D DFR87_05310 2Fe-2S iron-sulfur cluster binding domain-containing protein K18022 cutC; glyceraldehyde dehydrogenase small subunit [EC:1.2.99.8] D DFR87_08430 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D DFR87_05680 aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D DFR87_06780 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] C 00040 Pentose and glucuronate interconversions D DFR87_05840 alcohol dehydrogenase catalytic domain-containing protein K00008 SORD; L-iditol 2-dehydrogenase [EC:1.1.1.14] C 00051 Fructose and mannose metabolism [PATH:mhk00051] D DFR87_08095 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D DFR87_09415 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D DFR87_05590 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D DFR87_09080 NTP transferase domain-containing protein K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] D DFR87_11795 NDP-sugar synthase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] D DFR87_05840 alcohol dehydrogenase catalytic domain-containing protein K00008 SORD; L-iditol 2-dehydrogenase [EC:1.1.1.14] D DFR87_05680 aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D DFR87_06780 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D DFR87_11485 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 00052 Galactose metabolism [PATH:mhk00052] D DFR87_11455 aldose 1-epimerase K01785 galM; aldose 1-epimerase [EC:5.1.3.3] D DFR87_05940 NAD-dependent epimerase/dehydratase family protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D DFR87_05590 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D DFR87_11970 alcohol dehydrogenase catalytic domain-containing protein K18125 ssgdh; aldose 1-dehydrogenase [NAD(P)+] [EC:1.1.1.359] D DFR87_11980 mandelate racemase/muconate lactonizing enzyme family protein K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140] D DFR87_12295 2-dehydro-3-deoxyphosphogluconate aldolase K11395 kdpgA; 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase [EC:4.1.2.55] D DFR87_12300 sugar kinase K18126 sskdgK; 2-dehydro-3-deoxygluconokinase / 2-dehydro-3-deoxygalactonokinase [EC:2.7.1.178] D DFR87_00640 glycoside hydrolase family 31 protein K01187 malZ; alpha-glucosidase [EC:3.2.1.20] C 00053 Ascorbate and aldarate metabolism C 00500 Starch and sucrose metabolism [PATH:mhk00500] D DFR87_00640 glycoside hydrolase family 31 protein K01187 malZ; alpha-glucosidase [EC:3.2.1.20] D DFR87_11805 glycosyltransferase K00703 glgA; starch synthase [EC:2.4.1.21] D DFR87_11800 alpha-amylase K07405 E3.2.1.1A; alpha-amylase [EC:3.2.1.1] D DFR87_12435 glycoside hydrolase family 15 protein K01178 SGA1; glucoamylase [EC:3.2.1.3] D DFR87_00650 glgX; glycogen debranching protein GlgX K01214 ISA; isoamylase [EC:3.2.1.68] D DFR87_00645 malto-oligosyltrehalose synthase K06044 treY; (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase [EC:5.4.99.15] D DFR87_00665 treZ; malto-oligosyltrehalose trehalohydrolase K01236 treZ; maltooligosyltrehalose trehalohydrolase [EC:3.2.1.141] D DFR87_06280 glycosyltransferase K13057 treT; trehalose synthase [EC:2.4.1.245] D DFR87_05590 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D DFR87_08095 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D DFR87_09415 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:mhk00520] D DFR87_10695 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D DFR87_06630 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D DFR87_05590 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D DFR87_05700 NAD-dependent epimerase/dehydratase family protein K06118 SQD1; UDP-sulfoquinovose synthase [EC:3.13.1.1] D DFR87_05940 NAD-dependent epimerase/dehydratase family protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D DFR87_08095 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D DFR87_09415 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8] D DFR87_09080 NTP transferase domain-containing protein K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] D DFR87_11795 NDP-sugar synthase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] C 00620 Pyruvate metabolism [PATH:mhk00620] D DFR87_12270 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_12345 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_05465 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_04615 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_05210 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_04620 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05205 3-methyl-2-oxobutanoate dehydrogenase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05220 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04605 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04610 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D DFR87_05215 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D DFR87_04800 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D DFR87_04795 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D DFR87_01520 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_10985 FAD-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08450 NAD(P)-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08650 FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_11830 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D DFR87_10215 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D DFR87_11685 CoA-binding protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D DFR87_07130 malate dehydrogenase K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D DFR87_00040 malate dehydrogenase K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D DFR87_03910 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D DFR87_12130 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D DFR87_12135 Fe-S hydro-lyase subunit beta K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D DFR87_11430 fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D DFR87_03645 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D DFR87_11480 phosphoenolpyruvate carboxykinase (GTP) K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] D DFR87_04040 pyruvate, water dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D DFR87_10200 ppsA; pyruvate, water dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D DFR87_00060 malate synthase K01638 aceB; malate synthase [EC:2.3.3.9] D DFR87_03020 acetyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04160 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04375 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05445 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05450 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_10455 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_12260 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_02845 homoaconitate hydratase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] D DFR87_08010 citramalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] D DFR87_09835 lysS; homocitrate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:mhk00630] D DFR87_12270 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_12345 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_05465 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_00060 malate synthase K01638 aceB; malate synthase [EC:2.3.3.9] D DFR87_03910 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D DFR87_11115 citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1] D DFR87_05395 citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1] D DFR87_11400 acnA; aconitate hydratase AcnA K01681 ACO; aconitate hydratase [EC:4.2.1.3] D DFR87_03020 acetyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04160 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04375 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05445 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05450 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_10455 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_12260 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_02925 mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D DFR87_06075 acetyl-CoA carboxylase biotin carboxylase subunit K01964 K01964; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3] D DFR87_11880 methylmalonyl-CoA carboxyltransferase K15036 K15036; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15] D DFR87_06070 biotin/lipoyl-binding protein K15037 K15037; biotin carboxyl carrier protein D DFR87_08210 methylmalonyl-CoA mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D DFR87_02920 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D DFR87_03845 FAD-binding protein K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14] D DFR87_04015 FAD-binding protein K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14] D DFR87_03850 FAD-binding protein K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14] D DFR87_03840 4Fe-4S dicluster domain-containing protein K11473 glcF; glycolate dehydrogenase iron-sulfur subunit [EC:1.1.99.14] D DFR87_05520 D-glycerate dehydrogenase K00015 gyaR; glyoxylate reductase [EC:1.1.1.26] D DFR87_07830 phosphoglycolate phosphatase K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18] D DFR87_03405 phosphoglycolate phosphatase K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18] D DFR87_10645 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D DFR87_03805 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D DFR87_10470 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D DFR87_10360 aminomethyl-transferring glycine dehydrogenase subunit GcvPA K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2] D DFR87_10355 aminomethyl-transferring glycine dehydrogenase subunit GcvPB K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2] D DFR87_10365 gcvT; glycine cleavage system aminomethyltransferase GcvT K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D DFR87_01520 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_10985 FAD-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08450 NAD(P)-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08650 FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_11315 gcvH; glycine cleavage system protein GcvH K02437 gcvH; glycine cleavage system H protein D DFR87_10370 gcvH; glycine cleavage system protein GcvH K02437 gcvH; glycine cleavage system H protein D DFR87_10895 glycine cleavage system protein H K02437 gcvH; glycine cleavage system H protein D DFR87_08430 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D DFR87_02175 formate dehydrogenase subunit alpha K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9] D DFR87_12045 formate dehydrogenase subunit alpha K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9] D DFR87_12000 cyclase family protein K07130 kynB; arylformamidase [EC:3.5.1.9] C 00640 Propanoate metabolism [PATH:mhk00640] D DFR87_12270 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_12345 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_05465 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_11685 CoA-binding protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D DFR87_01520 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_10985 FAD-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08450 NAD(P)-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08650 FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_04615 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_05210 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_04620 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05205 3-methyl-2-oxobutanoate dehydrogenase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05220 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04605 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04610 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D DFR87_05215 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D DFR87_04345 enoyl-CoA hydratase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D DFR87_06075 acetyl-CoA carboxylase biotin carboxylase subunit K01964 K01964; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3] D DFR87_11880 methylmalonyl-CoA carboxyltransferase K15036 K15036; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15] D DFR87_06070 biotin/lipoyl-binding protein K15037 K15037; biotin carboxyl carrier protein D DFR87_05425 acetyl ornithine aminotransferase family protein K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D DFR87_02925 mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D DFR87_08210 methylmalonyl-CoA mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D DFR87_02920 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D DFR87_10790 succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D DFR87_10785 sucD; succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D DFR87_05410 MmgE/PrpD family protein K01720 prpD; 2-methylcitrate dehydratase [EC:4.2.1.79] D DFR87_05405 prpB; methylisocitrate lyase K03417 prpB; methylisocitrate lyase [EC:4.1.3.30] C 00650 Butanoate metabolism [PATH:mhk00650] D DFR87_03020 acetyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04160 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04375 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05445 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05450 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_10455 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_12260 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04345 enoyl-CoA hydratase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D DFR87_11360 CoA transferase subunit A K01039 gctA; glutaconate CoA-transferase, subunit A [EC:2.8.3.12] D DFR87_11365 CoA-transferase subunit beta K01040 gctB; glutaconate CoA-transferase, subunit B [EC:2.8.3.12] D DFR87_12485 arylmalonate decarboxylase K01799 nicE; maleate isomerase [EC:5.2.1.1] D DFR87_03130 succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D DFR87_12140 FAD-binding protein K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D DFR87_03125 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D DFR87_12155 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D DFR87_03120 disulfide reductase K00241 sdhC; succinate dehydrogenase cytochrome b subunit D DFR87_12145 succinate dehydrogenase K00241 sdhC; succinate dehydrogenase cytochrome b subunit D DFR87_12150 succinate dehydrogenase K00242 sdhD; succinate dehydrogenase membrane anchor subunit D DFR87_03115 succinate dehydrogenase K18859 sdhD; succinate dehydrogenase subunit D D DFR87_05425 acetyl ornithine aminotransferase family protein K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D DFR87_12060 4-hydroxybutyryl-CoA dehydratase K14534 abfD; 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] D DFR87_04615 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_05210 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_04620 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05205 3-methyl-2-oxobutanoate dehydrogenase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05220 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04605 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04610 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D DFR87_05215 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D DFR87_04800 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D DFR87_04795 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D DFR87_10450 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D DFR87_03800 alcohol dehydrogenase catalytic domain-containing protein K18382 adh1; NAD+-dependent secondary alcohol dehydrogenase Adh1 [EC:1.1.1.-] D DFR87_04035 thiamine pyrophosphate-requiring protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D DFR87_08860 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] C 00660 C5-Branched dibasic acid metabolism [PATH:mhk00660] D DFR87_04035 thiamine pyrophosphate-requiring protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D DFR87_08860 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D DFR87_10790 succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D DFR87_10785 sucD; succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D DFR87_02350 homoaconitate hydratase family protein K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D DFR87_02355 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D DFR87_06530 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] C 00562 Inositol phosphate metabolism [PATH:mhk00562] D DFR87_02895 D-fructose 1,6-bisphosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D DFR87_09005 L-myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] D DFR87_10210 inositol-3-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] D DFR87_01580 acid phosphatase K01114 plc; phospholipase C [EC:3.1.4.3] D DFR87_11485 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:mhk00190] D DFR87_09050 hypothetical protein K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2] D DFR87_08435 NADH-quinone oxidoreductase subunit B K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2] D DFR87_09045 NADH-quinone oxidoreductase subunit C K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2] D DFR87_09040 NADH-quinone oxidoreductase subunit D K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2] D DFR87_09035 nuoH; NADH-quinone oxidoreductase subunit NuoH K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2] D DFR87_09030 nuoI; NADH-quinone oxidoreductase subunit NuoI K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2] D DFR87_09025 NADH-quinone oxidoreductase subunit J K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2] D DFR87_09020 nuoK; NADH-quinone oxidoreductase subunit NuoK K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2] D DFR87_09015 oxidoreductase K15863 nuoLM; NADH-quinone oxidoreductase subunit L/M [EC:7.1.1.2] D DFR87_09010 nuoN; NADH-quinone oxidoreductase subunit NuoN K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2] D DFR87_03130 succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D DFR87_12140 FAD-binding protein K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D DFR87_03125 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D DFR87_12155 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D DFR87_03120 disulfide reductase K00241 sdhC; succinate dehydrogenase cytochrome b subunit D DFR87_12145 succinate dehydrogenase K00241 sdhC; succinate dehydrogenase cytochrome b subunit D DFR87_12150 succinate dehydrogenase K00242 sdhD; succinate dehydrogenase membrane anchor subunit D DFR87_03115 succinate dehydrogenase K18859 sdhD; succinate dehydrogenase subunit D D DFR87_08485 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D DFR87_05010 quinol oxidase K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9] D DFR87_04665 cytochrome c oxidase subunit II K02826 qoxA; cytochrome aa3-600 menaquinol oxidase subunit II [EC:7.1.1.5] D DFR87_05345 cytochrome bc complex cytochrome b subunit K24008 soxC; cytochrome aa3-type oxidase subunit III D DFR87_05350 cytochrome B6 K24009 soxB; cytochrome aa3-type oxidase subunit I [EC:7.1.1.4] D DFR87_05080 cytochrome B6 K24009 soxB; cytochrome aa3-type oxidase subunit I [EC:7.1.1.4] D DFR87_05355 cytochrome c oxidase subunit II K24010 soxA; cytochrome aa3-type oxidase subunit II [EC:7.1.1.4] D DFR87_05085 quinol oxidase subunit 2 K24010 soxA; cytochrome aa3-type oxidase subunit II [EC:7.1.1.4] D DFR87_04690 quinol oxidase subunit 1 K24011 soxM; cytochrome aa3-type oxidase subunit I/III [EC:7.1.1.4] D DFR87_08925 ATP synthase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] D DFR87_08920 V-type ATP synthase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B D DFR87_08915 V-type ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D D DFR87_08930 hypothetical protein K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E D DFR87_08935 V-type ATP synthase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F D DFR87_08940 V-type ATP synthase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I D DFR87_08910 V-type ATP synthase subunit K K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K D DFR87_05190 plasma-membrane proton-efflux P-type ATPase K01535 PMA1; H+-transporting ATPase [EC:7.1.2.1] D DFR87_02975 inorganic diphosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation by Calvin cycle [PATH:mhk00710] D DFR87_10485 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D DFR87_10480 phosphorylating glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] D DFR87_05680 aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D DFR87_09140 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D DFR87_09145 transketolase family protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D DFR87_06915 rpiA; ribose 5-phosphate isomerase A K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D DFR87_11485 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D DFR87_03645 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D DFR87_03910 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] C 00720 Other carbon fixation pathways [PATH:mhk00720] D DFR87_04615 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_05210 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_04620 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05205 3-methyl-2-oxobutanoate dehydrogenase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05220 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04605 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04610 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D DFR87_05215 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D DFR87_04040 pyruvate, water dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D DFR87_10200 ppsA; pyruvate, water dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D DFR87_03645 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D DFR87_03910 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D DFR87_12130 fumarate hydratase K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D DFR87_12135 Fe-S hydro-lyase subunit beta K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D DFR87_11430 fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D DFR87_03130 succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D DFR87_12140 FAD-binding protein K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D DFR87_03125 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D DFR87_12155 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D DFR87_03120 disulfide reductase K00241 sdhC; succinate dehydrogenase cytochrome b subunit D DFR87_12145 succinate dehydrogenase K00241 sdhC; succinate dehydrogenase cytochrome b subunit D DFR87_12150 succinate dehydrogenase K00242 sdhD; succinate dehydrogenase membrane anchor subunit D DFR87_03115 succinate dehydrogenase K18859 sdhD; succinate dehydrogenase subunit D D DFR87_10785 sucD; succinate--CoA ligase subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D DFR87_10790 succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D DFR87_12125 aldehyde dehydrogenase family protein K15038 K15038; succinyl-CoA reductase [EC:1.2.1.76] D DFR87_09790 aldehyde dehydrogenase family protein K15038 K15038; succinyl-CoA reductase [EC:1.2.1.76] D DFR87_11755 alcohol dehydrogenase catalytic domain-containing protein K14465 K14465; succinate semialdehyde reductase (NADPH) [EC:1.1.1.-] D DFR87_04145 AMP-binding protein K14466 K14466; 4-hydroxybutyrate---CoA ligase (AMP-forming) [EC:6.2.1.40] D DFR87_11765 phenylacetate--CoA ligase family protein K18861 K18861; 4-hydroxybutyrate---CoA ligase (AMP-forming) [EC:6.2.1.40] D DFR87_04415 AMP-binding protein K25774 K25774; 4-hydroxybutyrate---CoA ligase (AMP-forming) [EC:6.2.1.40] D DFR87_12060 4-hydroxybutyryl-CoA dehydratase K14534 abfD; 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] D DFR87_04185 3-hydroxyacyl-CoA dehydrogenase K15016 K15016; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35] D DFR87_04390 3-hydroxyacyl-CoA dehydrogenase family protein K15016 K15016; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35] D DFR87_11760 3-hydroxyacyl-CoA dehydrogenase K15016 K15016; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35] D DFR87_03020 acetyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04160 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04375 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05445 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05450 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_10455 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_12260 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04800 2-oxoacid:acceptor oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D DFR87_04795 2-oxoacid:ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D DFR87_03270 NADP-dependent isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D DFR87_11400 acnA; aconitate hydratase AcnA K01681 ACO; aconitate hydratase [EC:4.2.1.3] D DFR87_06075 acetyl-CoA carboxylase biotin carboxylase subunit K01964 K01964; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3] D DFR87_11880 methylmalonyl-CoA carboxyltransferase K15036 K15036; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15] D DFR87_06070 biotin/lipoyl-binding protein K15037 K15037; biotin carboxyl carrier protein D DFR87_03300 asd; aspartate-semialdehyde dehydrogenase K15017 K15017; malonyl-CoA/succinyl-CoA reductase (NADPH) [EC:1.2.1.75 1.2.1.76] D DFR87_08540 3-hydroxyacyl-CoA dehydrogenase family protein K15039 K15039; 3-hydroxypropionate dehydrogenase (NADP+) [EC:1.1.1.298] D DFR87_11465 acs; acetate--CoA ligase K15018 K15018; 3-hydroxypropionyl-coenzyme A synthetase [EC:6.2.1.36] D DFR87_08490 crotonase K15019 K15019; 3-hydroxypropionyl-coenzyme A dehydratase [EC:4.2.1.116] D DFR87_11745 alcohol dehydrogenase catalytic domain-containing protein K15020 K15020; acryloyl-coenzyme A reductase [EC:1.3.1.84] D DFR87_02925 mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D DFR87_02920 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D DFR87_08210 methylmalonyl-CoA mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D DFR87_12270 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_12345 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_05465 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] C 00680 Methane metabolism [PATH:mhk00680] D DFR87_02175 formate dehydrogenase subunit alpha K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9] D DFR87_12045 formate dehydrogenase subunit alpha K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9] D DFR87_10470 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D DFR87_08430 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D DFR87_10335 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D DFR87_03645 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D DFR87_03910 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D DFR87_05680 aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D DFR87_06780 fructose 1,6-bisphosphatase K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D DFR87_05675 hxlB; 6-phospho-3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D DFR87_05610 D-arabino 3-hexulose 6-phosphate aldehyde lyase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43] D DFR87_11015 FAD-binding protein K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D DFR87_11010 heterodisulfide reductase subunit B K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D DFR87_11030 disulfide reductase K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D DFR87_11005 4Fe-4S dicluster domain-containing protein K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D DFR87_11025 4Fe-4S dicluster domain-containing protein K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D DFR87_12270 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_12345 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_05465 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_04615 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_05210 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_04620 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05205 3-methyl-2-oxobutanoate dehydrogenase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05220 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04605 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04610 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D DFR87_05215 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D DFR87_04040 pyruvate, water dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D DFR87_10200 ppsA; pyruvate, water dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D DFR87_03560 histidine phosphatase family protein K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D DFR87_07345 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D DFR87_10300 3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] C 00910 Nitrogen metabolism [PATH:mhk00910] D DFR87_00450 MFS transporter K02575 NRT2; MFS transporter, NNP family, nitrate/nitrite transporter D DFR87_00455 molybdopterin-dependent oxidoreductase K00367 narB; ferredoxin-nitrate reductase [EC:1.7.7.2] D DFR87_00445 nitrite/sulfite reductase K00366 nirA; ferredoxin-nitrite reductase [EC:1.7.7.1] D DFR87_08115 glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D DFR87_10645 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D DFR87_03805 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D DFR87_04395 carbonic anhydrase K01673 cynT; carbonic anhydrase [EC:4.2.1.1] C 00920 Sulfur metabolism [PATH:mhk00920] D DFR87_12085 pyridine nucleotide-disulfide oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4] D DFR87_08190 NAD(P)/FAD-dependent oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4] D DFR87_04515 NAD(P)/FAD-dependent oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4] D DFR87_03820 NAD(P)/FAD-dependent oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4] D DFR87_04435 quinol oxidase K16936 doxA; thiosulfate dehydrogenase (quinone) small subunit [EC:1.8.5.2] D DFR87_04250 DoxX family membrane protein K16937 doxD; thiosulfate dehydrogenase (quinone) large subunit [EC:1.8.5.2] D DFR87_04440 DoxX family membrane protein K16937 doxD; thiosulfate dehydrogenase (quinone) large subunit [EC:1.8.5.2] D DFR87_04500 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D DFR87_03110 hypothetical protein K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] D DFR87_00480 selenium-binding protein K17285 SELENBP1; methanethiol oxidase [EC:1.8.3.4] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:mhk00061] D DFR87_01075 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D DFR87_08130 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D DFR87_09855 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D DFR87_01140 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D DFR87_10630 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:mhk00071] D DFR87_03020 acetyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04160 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04375 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05445 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05450 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_10455 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_12260 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04345 enoyl-CoA hydratase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D DFR87_05430 acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D DFR87_01140 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D DFR87_10630 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D DFR87_05115 NAD(P)/FAD-dependent oxidoreductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism [PATH:mhk00561] D DFR87_08430 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D DFR87_05700 NAD-dependent epimerase/dehydratase family protein K06118 SQD1; UDP-sulfoquinovose synthase [EC:3.13.1.1] C 00564 Glycerophospholipid metabolism [PATH:mhk00564] D DFR87_05330 glycerol-3-phosphate dehydrogenase K00113 glpC; glycerol-3-phosphate dehydrogenase subunit C D DFR87_01580 acid phosphatase K01114 plc; phospholipase C [EC:3.1.4.3] D DFR87_06735 NAD(P)-dependent glycerol-1-phosphate dehydrogenase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261] D DFR87_06930 geranylgeranylglyceryl/heptaprenylglyceryl phosphate synthase K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41] D DFR87_08840 MFS transporter K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42] D DFR87_08285 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67] D DFR87_03150 geranylgeranyl reductase family protein K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11] C 00565 Ether lipid metabolism D DFR87_01580 acid phosphatase K01114 plc; phospholipase C [EC:3.1.4.3] C 00600 Sphingolipid metabolism C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:mhk00230] D DFR87_03370 NUDIX domain-containing protein K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D DFR87_05590 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D DFR87_09685 prs; ribose-phosphate diphosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D DFR87_08595 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D DFR87_08600 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D DFR87_08590 phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D DFR87_04840 purT; formate-dependent phosphoribosylglycinamide formyltransferase K08289 purT; phosphoribosylglycinamide formyltransferase 2 [EC:6.3.1.21] D DFR87_08605 purL; phosphoribosylformylglycinamidine synthase subunit PurL K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3] D DFR87_08615 phosphoribosylformylglycinamidine synthase PurS protein K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3] D DFR87_08610 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D DFR87_08585 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D DFR87_11495 5-(carboxyamino)imidazole ribonucleotide synthase K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] D DFR87_11500 purE; 5-(carboxyamino)imidazole ribonucleotide mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D DFR87_08620 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D DFR87_07060 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D DFR87_07050 DUF1297 domain-containing protein K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23] D DFR87_07055 formate--phosphoribosylaminoimidazolecarboxamide ligase K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23] D DFR87_07120 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D DFR87_03535 DUF84 family protein K01529 yjjX; inosine/xanthosine triphosphatase [EC:3.6.1.73] D DFR87_07405 XTP/dITP diphosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D DFR87_11935 GMP synthase subunit A K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D DFR87_05820 GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D DFR87_10080 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D DFR87_12040 hypothetical protein K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D DFR87_00895 Ppx/GppA family phosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] D DFR87_07000 cyaB; class IV adenylate cyclase K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1] D DFR87_07045 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D DFR87_06395 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D DFR87_07590 AAA family ATPase K18532 AK6; adenylate kinase [EC:2.7.4.3] D DFR87_03355 AAA family ATPase K06928 NTPCR; nucleoside-triphosphatase [EC:3.6.1.15] D DFR87_07020 HIT domain-containing protein K19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53] D DFR87_00505 ureC; urease subunit alpha K01428 ureC; urease subunit alpha [EC:3.5.1.5] D DFR87_00510 urease subunit gamma K14048 ureAB; urease subunit gamma/beta [EC:3.5.1.5] C 00240 Pyrimidine metabolism [PATH:mhk00240] D DFR87_08555 carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D DFR87_08560 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D DFR87_08685 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D DFR87_08690 aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D DFR87_08700 dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3] D DFR87_08705 dihydroorotate dehydrogenase K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1] D DFR87_08680 orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D DFR87_08675 orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D DFR87_09845 UMP kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D DFR87_07120 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D DFR87_05615 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2] D DFR87_06380 AAA family ATPase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D DFR87_07105 uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9] D DFR87_07100 cdd; cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5] D DFR87_11640 deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13] D DFR87_06055 dCTP deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13] D DFR87_10080 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D DFR87_12040 hypothetical protein K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D DFR87_00885 thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D DFR87_00890 tmk; dTMP kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D DFR87_08305 tmk; dTMP kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D DFR87_09055 thyX; FAD-dependent thymidylate synthase K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:mhk00250] D DFR87_10255 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D DFR87_03170 arginase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5] D DFR87_04825 carbon-nitrogen hydrolase family protein K13566 NIT2; omega-amidase [EC:3.5.1.3] D DFR87_08570 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D DFR87_08565 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D DFR87_07045 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D DFR87_07060 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D DFR87_08685 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D DFR87_08690 aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D DFR87_05425 acetyl ornithine aminotransferase family protein K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D DFR87_08115 glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D DFR87_04215 aldehyde dehydrogenase family protein K00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88] D DFR87_10645 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D DFR87_03805 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D DFR87_08555 carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D DFR87_08560 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D DFR87_08610 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D DFR87_10695 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D DFR87_08595 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D DFR87_08600 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:mhk00260] D DFR87_10175 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D DFR87_10170 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D DFR87_08480 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D DFR87_03105 homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39] D DFR87_11690 pyridoxal-phosphate dependent enzyme K01733 thrC; threonine synthase [EC:4.2.3.1] D DFR87_10180 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D DFR87_10470 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D DFR87_08430 DUF4147 domain-containing protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D DFR87_03560 histidine phosphatase family protein K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D DFR87_07345 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D DFR87_10300 3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D DFR87_10360 aminomethyl-transferring glycine dehydrogenase subunit GcvPA K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2] D DFR87_10355 aminomethyl-transferring glycine dehydrogenase subunit GcvPB K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2] D DFR87_10365 gcvT; glycine cleavage system aminomethyltransferase GcvT K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D DFR87_01520 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_10985 FAD-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08450 NAD(P)-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08650 FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_11315 gcvH; glycine cleavage system protein GcvH K02437 gcvH; glycine cleavage system H protein D DFR87_10370 gcvH; glycine cleavage system protein GcvH K02437 gcvH; glycine cleavage system H protein D DFR87_10895 glycine cleavage system protein H K02437 gcvH; glycine cleavage system H protein D DFR87_07025 threonine ammonia-lyase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D DFR87_10225 tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D DFR87_10220 TrpB-like pyridoxal phosphate-dependent enzyme K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20] C 00270 Cysteine and methionine metabolism [PATH:mhk00270] D DFR87_07290 hypothetical protein K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D DFR87_07295 methionine synthase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D DFR87_05630 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D DFR87_08825 speD; adenosylmethionine decarboxylase K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D DFR87_10445 speD; adenosylmethionine decarboxylase K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D DFR87_06690 speE; polyamine aminopropyltransferase K00797 speE; spermidine synthase [EC:2.5.1.16] D DFR87_10845 nucleoside phosphorylase K00772 mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28] D DFR87_03190 S-methyl-5'-thioadenosine phosphorylase K00772 mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28] D DFR87_08365 amidohydrolase family protein K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28] D DFR87_06885 dcm; DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D DFR87_06755 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D DFR87_10175 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D DFR87_10170 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D DFR87_08480 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D DFR87_03110 hypothetical protein K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] D DFR87_10255 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D DFR87_04500 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D DFR87_03910 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D DFR87_12105 hypothetical protein K16845 suyA; (2R)-sulfolactate sulfo-lyase subunit alpha [EC:4.4.1.24] D DFR87_12100 D-galactarate dehydratase K16846 suyB; (2R)-sulfolactate sulfo-lyase subunit beta [EC:4.4.1.24] D DFR87_10300 3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D DFR87_07930 nuclease K23370 serK; L-serine kinase (ADP) [EC:2.7.1.226] C 00280 Valine, leucine and isoleucine degradation [PATH:mhk00280] D DFR87_01520 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_10985 FAD-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08450 NAD(P)-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08650 FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_05430 acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D DFR87_04345 enoyl-CoA hydratase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D DFR87_06075 acetyl-CoA carboxylase biotin carboxylase subunit K01964 K01964; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3] D DFR87_11880 methylmalonyl-CoA carboxyltransferase K15036 K15036; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15] D DFR87_06070 biotin/lipoyl-binding protein K15037 K15037; biotin carboxyl carrier protein D DFR87_02925 mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D DFR87_08210 methylmalonyl-CoA mutase K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] D DFR87_02920 methylmalonyl-CoA mutase K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] D DFR87_09865 NAD-binding protein K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] D DFR87_02685 enoyl-CoA hydratase/isomerase family protein K13766 liuC; methylglutaconyl-CoA hydratase [EC:4.2.1.18] D DFR87_03020 acetyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04160 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04375 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05445 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05450 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_10455 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_12260 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_10450 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:mhk00290] D DFR87_07025 threonine ammonia-lyase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D DFR87_02350 homoaconitate hydratase family protein K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D DFR87_02355 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D DFR87_06530 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D DFR87_04035 thiamine pyrophosphate-requiring protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D DFR87_08860 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D DFR87_08870 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D DFR87_03310 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D DFR87_02845 homoaconitate hydratase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] D DFR87_08010 citramalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] D DFR87_09835 lysS; homocitrate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00300 Lysine biosynthesis [PATH:mhk00300] D DFR87_08480 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D DFR87_10175 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D DFR87_10170 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D DFR87_08170 dihydrodipicolinate synthase family protein K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D DFR87_02070 ArgE/DapE family deacylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D DFR87_00525 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K05825 LYSN; 2-aminoadipate transaminase [EC:2.6.1.-] D DFR87_07885 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K05825 LYSN; 2-aminoadipate transaminase [EC:2.6.1.-] D DFR87_05975 sulfonate ABC transporter K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW D DFR87_05970 lysX; lysine biosynthesis protein LysX K05827 lysX; [lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase [EC:6.3.2.43] D DFR87_05985 [LysW]-aminoadipate/[LysW]-glutamate kinase K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19] D DFR87_05990 N-acetyl-gamma-glutamyl-phosphate reductase K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106] D DFR87_05965 acetylornithine/succinylornithine family transaminase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124] D DFR87_05960 N-acetyl-lysine deacetylase K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132] C 00310 Lysine degradation [PATH:mhk00310] D DFR87_01520 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_10985 FAD-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08450 NAD(P)-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08650 FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_04345 enoyl-CoA hydratase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D DFR87_03020 acetyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04160 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04375 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05445 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05450 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_10455 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_12260 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00220 Arginine biosynthesis [PATH:mhk00220] D DFR87_10155 argF; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D DFR87_08570 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D DFR87_08565 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D DFR87_00505 ureC; urease subunit alpha K01428 ureC; urease subunit alpha [EC:3.5.1.5] D DFR87_00510 urease subunit gamma K14048 ureAB; urease subunit gamma/beta [EC:3.5.1.5] D DFR87_00430 arginine deiminase K01478 arcA; arginine deiminase [EC:3.5.3.6] D DFR87_08610 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D DFR87_10645 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D DFR87_03805 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D DFR87_08555 carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D DFR87_08560 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D DFR87_08115 glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D DFR87_10255 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D DFR87_05975 sulfonate ABC transporter K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW D DFR87_08550 lysX; lysine biosynthesis protein LysX K19412 argX; glutamate---[amino group carrier protein] ligase [EC:6.3.2.60] D DFR87_05985 [LysW]-aminoadipate/[LysW]-glutamate kinase K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19] D DFR87_05990 N-acetyl-gamma-glutamyl-phosphate reductase K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106] D DFR87_05965 acetylornithine/succinylornithine family transaminase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124] D DFR87_05960 N-acetyl-lysine deacetylase K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132] C 00330 Arginine and proline metabolism [PATH:mhk00330] D DFR87_11860 creatininase family protein K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10] D DFR87_01485 hydantoinase/oxoprolinase family protein K01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14] D DFR87_01480 5-oxoprolinase K01474 hyuB; N-methylhydantoinase B [EC:3.5.2.14] D DFR87_07475 speB; agmatinase K01480 speB; agmatinase [EC:3.5.3.11] D DFR87_05160 speB; agmatinase K01480 speB; agmatinase [EC:3.5.3.11] D DFR87_06690 speE; polyamine aminopropyltransferase K00797 speE; spermidine synthase [EC:2.5.1.16] D DFR87_08825 speD; adenosylmethionine decarboxylase K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D DFR87_10445 speD; adenosylmethionine decarboxylase K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D DFR87_00875 pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D DFR87_04215 aldehyde dehydrogenase family protein K00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88] D DFR87_10255 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] C 00340 Histidine metabolism [PATH:mhk00340] D DFR87_08790 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17] D DFR87_08765 hisE; phosphoribosyl-ATP diphosphatase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31] D DFR87_08755 hisI; phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] D DFR87_08785 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D DFR87_08760 hisH; imidazole glycerol phosphate synthase subunit HisH K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] D DFR87_08775 hisF; imidazole glycerol phosphate synthase subunit HisF K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] D DFR87_08780 hisBd; imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19] D DFR87_08795 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D DFR87_08770 hisD; histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23] C 00350 Tyrosine metabolism [PATH:mhk00350] D DFR87_10255 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D DFR87_08795 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D DFR87_00965 4-hydroxyphenylacetate 3-hydroxylase K00483 hpaB; 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] D DFR87_09780 4-hydroxyphenylacetate 3-hydroxylase K00483 hpaB; 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] C 00360 Phenylalanine metabolism [PATH:mhk00360] D DFR87_04385 AMP-binding protein K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30] D DFR87_05435 hotdog fold thioesterase K02614 paaI; acyl-CoA thioesterase [EC:3.1.2.-] D DFR87_04350 enoyl-CoA hydratase K15866 paaG; 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase [EC:5.3.3.18] D DFR87_04345 enoyl-CoA hydratase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D DFR87_10255 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D DFR87_08795 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D DFR87_05115 NAD(P)/FAD-dependent oxidoreductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3] C 00380 Tryptophan metabolism [PATH:mhk00380] D DFR87_12000 cyclase family protein K07130 kynB; arylformamidase [EC:3.5.1.9] D DFR87_01520 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_10985 FAD-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08450 NAD(P)-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08650 FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_04345 enoyl-CoA hydratase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D DFR87_03020 acetyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04160 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04375 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05445 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05450 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_10455 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_12260 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:mhk00400] D DFR87_09155 aroF; 3-deoxy-7-phosphoheptulonate synthase K03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D DFR87_09160 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4] D DFR87_09215 type I 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10] D DFR87_09175 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D DFR87_09180 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D DFR87_09170 aroC; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D DFR87_10240 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D DFR87_10245 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D DFR87_10230 trpD; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18] D DFR87_10235 phosphoribosylanthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24] D DFR87_10250 trpC; indole-3-glycerol phosphate synthase TrpC K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48] D DFR87_10225 tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D DFR87_10220 TrpB-like pyridoxal phosphate-dependent enzyme K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D DFR87_09150 chorismate mutase K14187 tyrA; chorismate mutase / prephenate dehydrogenase [EC:5.4.99.5 1.3.1.12] D DFR87_07030 ACT domain-containing protein K04518 pheA2; prephenate dehydratase [EC:4.2.1.51] D DFR87_10255 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D DFR87_08795 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism [PATH:mhk00410] D DFR87_05425 acetyl ornithine aminotransferase family protein K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D DFR87_02800 phosphopantothenate/pantothenate synthetase K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] D DFR87_04345 enoyl-CoA hydratase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] C 00430 Taurine and hypotaurine metabolism D DFR87_09390 hypothetical protein K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D DFR87_05585 gamma-glutamyltransferase family protein K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:mhk00450] D DFR87_03110 hypothetical protein K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] D DFR87_07290 hypothetical protein K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D DFR87_07295 methionine synthase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D DFR87_03440 aminotransferase class V-fold PLP-dependent enzyme K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D DFR87_02890 trxB; thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D DFR87_08945 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism [PATH:mhk00460] D DFR87_09390 hypothetical protein K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D DFR87_05585 gamma-glutamyltransferase family protein K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D DFR87_03170 arginase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5] D DFR87_10470 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism D DFR87_08610 purQ; phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] C 00480 Glutathione metabolism [PATH:mhk00480] D DFR87_09390 hypothetical protein K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D DFR87_05585 gamma-glutamyltransferase family protein K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D DFR87_05300 peptidase M1 K01256 pepN; aminopeptidase N [EC:3.4.11.2] D DFR87_03270 NADP-dependent isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D DFR87_06690 speE; polyamine aminopropyltransferase K00797 speE; spermidine synthase [EC:2.5.1.16] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis C 00541 O-Antigen nucleotide sugar biosynthesis C 00550 Peptidoglycan biosynthesis C 00552 Teichoic acid biosynthesis [PATH:mhk00552] D DFR87_01055 undecaprenyl-diphosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:mhk00730] D DFR87_02965 thiD; bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3] D DFR87_07430 thiazole biosynthesis protein K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] D DFR87_02705 phosphomethylpyrimidine kinase K21220 thiN; thiamine-phosphate diphosphorylase [EC:2.5.1.3] D DFR87_07070 thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16] D DFR87_03355 AAA family ATPase K06928 NTPCR; nucleoside-triphosphatase [EC:3.6.1.15] D DFR87_06395 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D DFR87_12335 tenA; thiaminase II K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2] C 00740 Riboflavin metabolism [PATH:mhk00740] D DFR87_07225 GTP cyclohydrolase IIa K08096 gch3; GTP cyclohydrolase IIa [EC:3.5.4.29] D DFR87_07080 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302] D DFR87_07210 3,4-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12] D DFR87_07220 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D DFR87_07215 riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9] D DFR87_09975 DUF120 domain-containing protein K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161] D DFR87_09980 DUF357 domain-containing protein K14656 ribL; FAD synthetase [EC:2.7.7.2] D DFR87_03370 NUDIX domain-containing protein K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D DFR87_07440 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00750 Vitamin B6 metabolism [PATH:mhk00750] D DFR87_11690 pyridoxal-phosphate dependent enzyme K01733 thrC; threonine synthase [EC:4.2.3.1] D DFR87_10180 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D DFR87_08895 pdxS; pyridoxal 5'-phosphate synthase lyase subunit PdxS K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6] D DFR87_08890 pdxT; pyridoxal 5'-phosphate synthase glutaminase subunit PdxT K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6] C 00760 Nicotinate and nicotinamide metabolism [PATH:mhk00760] D DFR87_10535 nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21] D DFR87_06990 nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1] D DFR87_03325 NAD+ synthase K01916 nadE; NAD+ synthase [EC:6.3.1.5] D DFR87_00725 NAD-dependent protein deacylase K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313] D DFR87_03455 NAD(+) kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] D DFR87_12475 N-acetylmuramoyl-L-alanine amidase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] D DFR87_12485 arylmalonate decarboxylase K01799 nicE; maleate isomerase [EC:5.2.1.1] D DFR87_12740 carboxyvinyl-carboxyphosphonate phosphorylmutase K20454 dml; 2,3-dimethylmalate lyase [EC:4.1.3.32] C 00770 Pantothenate and CoA biosynthesis [PATH:mhk00770] D DFR87_04035 thiamine pyrophosphate-requiring protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D DFR87_08860 acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D DFR87_08870 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D DFR87_03310 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D DFR87_02805 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11] D DFR87_02795 GHMP kinase K06982 pok; pantoate kinase [EC:2.7.1.169] D DFR87_02800 phosphopantothenate/pantothenate synthetase K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] D DFR87_06090 coaBC; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D DFR87_07340 DUF359 domain-containing protein K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237] C 00780 Biotin metabolism [PATH:mhk00780] D DFR87_01075 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D DFR87_08130 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D DFR87_09855 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D DFR87_08445 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:mhk00785] D DFR87_10945 radical SAM protein K09711 lipS1; lipoyl synthase D DFR87_11175 radical SAM protein K09711 lipS1; lipoyl synthase D DFR87_10950 radical SAM protein K24689 lipS2; lipoyl synthase D DFR87_11170 radical SAM protein K24689 lipS2; lipoyl synthase D DFR87_11180 lipoate--protein ligase family protein K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D DFR87_10940 lipoate--protein ligase family protein K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D DFR87_11320 lipoate--protein ligase family protein K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D DFR87_01520 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_10985 FAD-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08450 NAD(P)-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08650 FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_10360 aminomethyl-transferring glycine dehydrogenase subunit GcvPA K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2] D DFR87_10355 aminomethyl-transferring glycine dehydrogenase subunit GcvPB K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2] D DFR87_10365 gcvT; glycine cleavage system aminomethyltransferase GcvT K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D DFR87_11315 gcvH; glycine cleavage system protein GcvH K02437 gcvH; glycine cleavage system H protein D DFR87_10370 gcvH; glycine cleavage system protein GcvH K02437 gcvH; glycine cleavage system H protein D DFR87_10895 glycine cleavage system protein H K02437 gcvH; glycine cleavage system H protein C 00790 Folate biosynthesis [PATH:mhk00790] D DFR87_10650 folE; GTP cyclohydrolase I FolE K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16] D DFR87_02875 6-pyruvoyl tetrahydrobiopterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D DFR87_03245 4a-hydroxytetrahydrobiopterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] D DFR87_08635 radical SAM protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D DFR87_10905 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D DFR87_04915 queC; 7-cyano-7-deazaguanine synthase QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D DFR87_02850 DUF115 domain-containing protein K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D DFR87_10500 beta-ribofuranosylaminobenzene 5'-phosphate synthase K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54] D DFR87_03205 RimK family alpha-L-glutamate ligase K15740 mptN; tetrahydromethanopterin:alpha-L-glutamate ligase [EC:6.3.2.33] D DFR87_10660 moaA; GTP 3',8-cyclase MoaA K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D DFR87_08245 moaC; cyclic pyranopterin monophosphate synthase MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D DFR87_02960 MoaD family protein K21142 moaX; MoaE-MoaD fusion protein [EC:2.8.1.12] D DFR87_04890 molybdenum cofactor biosynthesis protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D DFR87_08380 molybdopterin molybdenumtransferase MoeA K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] D DFR87_02770 NTP transferase domain-containing protein K07141 mocA; molybdenum cofactor cytidylyltransferase [EC:2.7.7.76] D DFR87_08375 NTP transferase domain-containing protein K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77] C 00670 One carbon pool by folate [PATH:mhk00670] D DFR87_10470 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D DFR87_10365 gcvT; glycine cleavage system aminomethyltransferase GcvT K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D DFR87_09055 thyX; FAD-dependent thymidylate synthase K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148] D DFR87_01555 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:mhk00860] D DFR87_07825 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D DFR87_05750 glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70] D DFR87_05740 hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D DFR87_05745 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D DFR87_05735 hemC; hydroxymethylbilane synthase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61] D DFR87_05730 uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D DFR87_02750 cobA; uroporphyrinogen-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] D DFR87_05755 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76] D DFR87_05225 radical SAM protein K22226 ahbC; Fe-coproporphyrin III synthase D DFR87_05230 radical SAM protein K22227 ahbD; AdoMet-dependent heme synthase [EC:1.3.98.6] D DFR87_08485 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D DFR87_07310 sirohydrochlorin cobaltochelatase K03795 cbiX; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] D DFR87_03210 cobalt-precorrin-2 C(20)-methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151] D DFR87_08025 cobalt-factor III C(17)-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272] D DFR87_03215 cobalt-precorrin-4 C(11)-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271] D DFR87_08030 cobalamin biosynthesis protein CbiG K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12] D DFR87_07980 cbiD; cobalamin biosynthesis protein CbiD K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195] D DFR87_07945 precorrin-6B methylase K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196] D DFR87_07975 cobalt-precorrin-7 (C(5))-methyltransferase K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289] D DFR87_07990 precorrin-8X methylmutase K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60] D DFR87_07195 cobyrinate a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11] D DFR87_08040 cobaltochelatase subunit CobN K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2] D DFR87_10745 cob(I)yrinic acid a,c-diamide adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D DFR87_08810 cob(I)yrinic acid a,c-diamide adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D DFR87_05825 cobyric acid synthase K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10] D DFR87_05835 cobalamin biosynthesis protein K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10] D DFR87_03815 NTP transferase domain-containing protein K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62] D DFR87_05830 adenosylcobinamide-GDP ribazoletransferase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26] D DFR87_08045 VWA domain-containing protein K03404 chlD; magnesium chelatase subunit D [EC:6.6.1.1] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:mhk00130] D DFR87_08005 ubiA; 4-hydroxybenzoate octaprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] D DFR87_10185 UbiD family decarboxylase K03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98] D DFR87_07440 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D DFR87_12600 methyltransferase domain-containing protein K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201] D DFR87_04055 wrbA; NAD(P)H:quinone oxidoreductase K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:mhk00900] D DFR87_03020 acetyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04160 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04375 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05445 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05450 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_10455 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_12260 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_10450 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D DFR87_10465 hmgA; hydroxymethylglutaryl-CoA reductase (NADPH) K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34] D DFR87_10700 mvk; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36] D DFR87_10870 GHMP kinase K00938 E2.7.4.2; phosphomevalonate kinase [EC:2.7.4.2] D DFR87_10865 mvaD; diphosphomevalonate decarboxylase K01597 MVD; diphosphomevalonate decarboxylase [EC:4.1.1.33] D DFR87_07785 uridylate kinase K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26] D DFR87_07440 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D DFR87_07790 type 2 isopentenyl-diphosphate Delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] D DFR87_07795 polyprenyl synthetase family protein K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D DFR87_03200 polyprenyl synthetase family protein K21268 gdS-2; hexaprenyl diphosphate synthase [EC:2.5.1.82] D DFR87_05955 uppS; di-trans,poly-cis-decaprenylcistransferase K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis [PATH:mhk00906] D DFR87_06350 phytoene/squalene synthase family protein K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32] D DFR87_06360 crtI; phytoene desaturase K10027 crtI; phytoene desaturase [EC:1.3.99.26 1.3.99.28 1.3.99.29 1.3.99.31] D DFR87_06355 porin K15746 crtZ; beta-carotene 3-hydroxylase [EC:1.14.15.24] C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation [PATH:mhk00907] D DFR87_04345 enoyl-CoA hydratase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D DFR87_09140 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D DFR87_09145 transketolase family protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis [PATH:mhk00523] D DFR87_10690 NTP transferase domain-containing protein K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D DFR87_09430 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D DFR87_06630 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D DFR87_09425 NAD-dependent epimerase/dehydratase family protein K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D DFR87_09440 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D DFR87_03425 sugar nucleotide-binding protein K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] D DFR87_09435 sugar nucleotide-binding protein K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics D DFR87_09425 NAD-dependent epimerase/dehydratase family protein K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis D DFR87_00350 penicillin acylase K01434 pac; penicillin G amidase [EC:3.5.1.11] C 00332 Carbapenem biosynthesis C 00261 Monobactam biosynthesis [PATH:mhk00261] D DFR87_10175 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D DFR87_10170 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D DFR87_08170 dihydrodipicolinate synthase family protein K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:mhk00521] D DFR87_05590 glmM; phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D DFR87_09005 L-myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] D DFR87_10210 inositol-3-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] D DFR87_02895 D-fructose 1,6-bisphosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D DFR87_10690 NTP transferase domain-containing protein K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D DFR87_09430 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D DFR87_06630 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D DFR87_09425 NAD-dependent epimerase/dehydratase family protein K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D DFR87_09440 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D DFR87_03425 sugar nucleotide-binding protein K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] D DFR87_09435 sugar nucleotide-binding protein K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 00524 Neomycin, kanamycin and gentamicin biosynthesis C 00525 Acarbose and validamycin biosynthesis [PATH:mhk00525] D DFR87_10690 NTP transferase domain-containing protein K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D DFR87_09430 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D DFR87_06630 NTP transferase domain-containing protein K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D DFR87_09425 NAD-dependent epimerase/dehydratase family protein K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] C 00401 Novobiocin biosynthesis [PATH:mhk00401] D DFR87_09150 chorismate mutase K14187 tyrA; chorismate mutase / prephenate dehydrogenase [EC:5.4.99.5 1.3.1.12] D DFR87_10255 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D DFR87_08795 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D DFR87_10240 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D DFR87_10245 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis D DFR87_01075 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D DFR87_08130 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D DFR87_09855 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics C 00999 Biosynthesis of various plant secondary metabolites D DFR87_05630 methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation [PATH:mhk00362] D DFR87_07875 alpha/beta fold hydrolase K01055 pcaD; 3-oxoadipate enol-lactonase [EC:3.1.1.24] D DFR87_05115 NAD(P)/FAD-dependent oxidoreductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3] D DFR87_04345 enoyl-CoA hydratase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D DFR87_03020 acetyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04160 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04375 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05445 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05450 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_10455 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_12260 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00627 Aminobenzoate degradation [PATH:mhk00627] D DFR87_10215 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D DFR87_12160 thiamine pyrophosphate-binding protein K01576 mdlC; benzoylformate decarboxylase [EC:4.1.1.7] D DFR87_07440 UbiX family flavin prenyltransferase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D DFR87_04345 enoyl-CoA hydratase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] C 00364 Fluorobenzoate degradation [PATH:mhk00364] D DFR87_12235 dienelactone hydrolase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45] C 00625 Chloroalkane and chloroalkene degradation D DFR87_02135 haloacid dehalogenase type II K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2] C 00361 Chlorocyclohexane and chlorobenzene degradation [PATH:mhk00361] D DFR87_12235 dienelactone hydrolase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45] D DFR87_02135 haloacid dehalogenase type II K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2] C 00623 Toluene degradation [PATH:mhk00623] D DFR87_12235 dienelactone hydrolase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45] C 00622 Xylene degradation C 00633 Nitrotoluene degradation D DFR87_04615 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_05210 pyruvate ferredoxin oxidoreductase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D DFR87_04620 pyruvate synthase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05205 3-methyl-2-oxobutanoate dehydrogenase subunit beta K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D DFR87_05220 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04605 pyruvate synthase K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D DFR87_04610 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D DFR87_05215 4Fe-4S dicluster domain-containing protein K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] C 00642 Ethylbenzene degradation C 00643 Styrene degradation D DFR87_11360 CoA transferase subunit A K01039 gctA; glutaconate CoA-transferase, subunit A [EC:2.8.3.12] D DFR87_11365 CoA-transferase subunit beta K01040 gctB; glutaconate CoA-transferase, subunit B [EC:2.8.3.12] C 00791 Atrazine degradation D DFR87_00505 ureC; urease subunit alpha K01428 ureC; urease subunit alpha [EC:3.5.1.5] D DFR87_00510 urease subunit gamma K14048 ureAB; urease subunit gamma/beta [EC:3.5.1.5] C 00930 Caprolactam degradation D DFR87_04345 enoyl-CoA hydratase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] C 00363 Bisphenol degradation C 00621 Dioxin degradation C 00626 Naphthalene degradation C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:mhk03020] D DFR87_07140 DNA-directed RNA polymerase subunit B K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6] D DFR87_07145 rpoA1; DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6] D DFR87_07150 rpoA2; DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6] D DFR87_07745 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6] D DFR87_09270 DNA-directed RNA polymerase subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6] D DFR87_07330 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6] D DFR87_06660 DNA-directed RNA polymerase subunit F K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6] D DFR87_06835 DNA-directed RNA polymerase subunit G K03052 rpoG; DNA-directed RNA polymerase subunit G [EC:2.7.7.6] D DFR87_07135 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6] D DFR87_10310 DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6] D DFR87_07765 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6] D DFR87_07480 DNA-directed RNA polymerase subunit P K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6] D DFR87_07240 RNA polymerase Rpo13 K00960 rpo13; DNA-directed RNA polymerase subunit 13 [EC:2.7.7.6] C 03022 Basal transcription factors [PATH:mhk03022] D DFR87_07490 transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D DFR87_10000 transcription initiation factor IIB family protein K03124 TFIIB; transcription initiation factor TFIIB D DFR87_10020 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D DFR87_06880 tfe; transcription factor E K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha D DFR87_09230 DEAD/DEAH box helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:mhk03010] D DFR87_07770 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D DFR87_06485 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D DFR87_07735 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D DFR87_06415 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D DFR87_07175 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D DFR87_06440 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D DFR87_07760 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D DFR87_07185 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D DFR87_07740 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D DFR87_07165 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D DFR87_07730 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D DFR87_06445 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D DFR87_07300 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D DFR87_06470 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D DFR87_06495 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D DFR87_06635 30S ribosomal protein S3ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae D DFR87_06455 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e D DFR87_07315 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e D DFR87_05950 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e D DFR87_06785 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e D DFR87_10540 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e D DFR87_07425 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e D DFR87_07365 30S ribosomal protein S25e K02975 RP-S25e; small subunit ribosomal protein S25e D DFR87_08900 30S ribosomal protein S26e K02976 RP-S26e; small subunit ribosomal protein S26e D DFR87_09610 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e D DFR87_07420 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D DFR87_07110 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e D DFR87_10055 30S ribosomal protein S30e K02983 RP-S30e; small subunit ribosomal protein S30e D DFR87_10595 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D DFR87_06500 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D DFR87_06515 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D DFR87_06450 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D DFR87_06435 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D DFR87_10600 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D DFR87_10590 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D DFR87_10605 50S ribosomal protein P1 K02869 RP-L12; large subunit ribosomal protein L12 D DFR87_07755 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D DFR87_06465 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D DFR87_06405 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D DFR87_06420 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D DFR87_06490 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D DFR87_06505 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D DFR87_06460 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D DFR87_06480 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D DFR87_06410 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D DFR87_06510 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e D DFR87_07820 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D DFR87_09255 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e D DFR87_07255 50S ribosomal protein L14e K02875 RP-L14e; large subunit ribosomal protein L14e D DFR87_06620 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e D DFR87_07750 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e D DFR87_06425 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e D DFR87_06665 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e D DFR87_07115 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e D DFR87_07155 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e D DFR87_10555 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e D DFR87_06430 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e D DFR87_06385 50S ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e D DFR87_06685 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e D DFR87_06575 50S ribosomal protein L37ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae D DFR87_10550 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e D DFR87_05805 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D DFR87_09605 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e D DFR87_10565 50S ribosomal protein L18a K02944 RP-LX; large subunit ribosomal protein LX D DFR87_09820 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D DFR87_09815 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:mhk00970] D DFR87_10740 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D DFR87_10755 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D DFR87_06970 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D DFR87_10090 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D DFR87_10620 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D DFR87_08980 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D DFR87_06910 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D DFR87_09295 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D DFR87_07810 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D DFR87_07280 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D DFR87_10430 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D DFR87_10435 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D DFR87_02225 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D DFR87_06315 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D DFR87_09105 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D DFR87_07640 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D DFR87_06095 tRNA-His K14226 tRNA-His; tRNA His D DFR87_09640 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D DFR87_06670 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D DFR87_08320 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D DFR87_02640 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D DFR87_09830 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D DFR87_06700 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D DFR87_10625 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D DFR87_10440 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D DFR87_06750 tRNA-Ile K14230 tRNA-Met; tRNA Met D DFR87_06080 tRNA-Met K14230 tRNA-Met; tRNA Met D DFR87_10415 tRNA-Met K14230 tRNA-Met; tRNA Met D DFR87_06330 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D DFR87_09740 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D DFR87_10725 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D DFR87_07815 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D DFR87_07190 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D DFR87_07275 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D DFR87_08330 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D DFR87_06695 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D DFR87_10410 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D DFR87_07065 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D DFR87_10830 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D DFR87_07645 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D DFR87_06675 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D DFR87_06895 tRNA-Val K14237 tRNA-Val; tRNA Val D DFR87_06705 tRNA-Val K14237 tRNA-Val; tRNA Val D DFR87_05660 tRNA-Val K14237 tRNA-Val; tRNA Val D DFR87_07825 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D DFR87_03650 amidase K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D DFR87_09965 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D DFR87_07095 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D DFR87_09960 gatC; Asp-tRNA(Asn) amidotransferase subunit GatC K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D DFR87_10060 gatD; Glu-tRNA(Gln) amidotransferase subunit GatD K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7] D DFR87_10065 gatE; Glu-tRNA(Gln) amidotransferase subunit GatE K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7] D DFR87_10610 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D DFR87_04150 alanyl-tRNA editing protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D DFR87_05795 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D DFR87_07470 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D DFR87_10805 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D DFR87_08745 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D DFR87_08100 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D DFR87_08945 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D DFR87_10260 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D DFR87_02660 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D DFR87_08805 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D DFR87_06525 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D DFR87_07655 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D DFR87_10095 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D DFR87_08905 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D DFR87_06820 histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D DFR87_07865 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D DFR87_07870 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D DFR87_07710 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D DFR87_07560 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:mhk03060] D DFR87_06400 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D DFR87_09875 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D DFR87_10575 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D DFR87_05945 hypothetical protein K03105 SRP19; signal recognition particle subunit SRP19 D DFR87_02550 translocase K03116 tatA; sec-independent protein translocase protein TatA D DFR87_02555 tatA; twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA D DFR87_02545 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC D DFR87_12545 hypothetical protein K13280 SEC11; signal peptidase I [EC:3.4.21.89] D DFR87_10350 signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:mhk04122] D DFR87_04500 sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D DFR87_04245 response regulator SirA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D DFR87_00535 response regulator SirA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D DFR87_10660 moaA; GTP 3',8-cyclase MoaA K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D DFR87_02960 MoaD family protein K21142 moaX; MoaE-MoaD fusion protein [EC:2.8.1.12] D DFR87_09135 HesA/MoeB/ThiF family protein K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80] D DFR87_08245 moaC; cyclic pyranopterin monophosphate synthase MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D DFR87_04890 molybdenum cofactor biosynthesis protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D DFR87_11810 thiamine biosynthesis protein ThiS K03154 thiS; sulfur carrier protein C 03050 Proteasome [PATH:mhk03050] D DFR87_06860 pan; proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit D DFR87_06600 psmA; archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D DFR87_06825 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D DFR87_08230 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] C 03018 RNA degradation [PATH:mhk03018] D DFR87_09265 RNA-binding protein K07573 CSL4; exosome complex component CSL4 D DFR87_06590 RNA-binding protein K03679 RRP4; exosome complex component RRP4 D DFR87_06580 exosome complex protein Rrp42 K12589 RRP42; exosome complex component RRP42 D DFR87_06585 exosome complex exonuclease Rrp41 K11600 RRP41; exosome complex component RRP41 D DFR87_10335 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D DFR87_11245 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] B B 09124 Replication and repair C 03030 DNA replication [PATH:mhk03030] D DFR87_07705 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D DFR87_07305 reverse transcriptase-like protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D DFR87_03045 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D DFR87_11550 DNA polymerase II K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D DFR87_08975 DNA-directed DNA polymerase I K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D DFR87_08270 AAA domain-containing protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D DFR87_09655 priS; DNA primase small subunit PriS K02683 priS; DNA primase small subunit [EC:2.7.7.102] D DFR87_08950 DNA primase regulatory subunit PriL K18882 priL; DNA primase large subunit D DFR87_07235 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D DFR87_07285 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen D DFR87_09660 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D DFR87_08235 replication factor C small subunit K04801 rfcS; replication factor C small subunit D DFR87_08240 replication factor C large subunit K04800 rfcL; replication factor C large subunit D DFR87_05760 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D DFR87_06060 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03410 Base excision repair [PATH:mhk03410] D DFR87_07935 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D DFR87_07235 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D DFR87_07285 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen D DFR87_09660 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D DFR87_05760 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D DFR87_06060 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D DFR87_01230 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D DFR87_08135 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D DFR87_11560 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D DFR87_03400 TIM barrel protein K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] C 03420 Nucleotide excision repair [PATH:mhk03420] D DFR87_09230 DEAD/DEAH box helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] D DFR87_06555 multidrug MFS transporter K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] D DFR87_07235 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D DFR87_07285 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen D DFR87_09660 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D DFR87_06060 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03430 Mismatch repair [PATH:mhk03430] D DFR87_07235 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D DFR87_07285 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen D DFR87_09660 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D DFR87_06060 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03440 Homologous recombination C 03450 Non-homologous end-joining D DFR87_05760 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 D DFR87_07335 DNA-binding protein K15171 SUPT4H1; transcription elongation factor SPT4 D DFR87_10585 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5 C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:mhk02010] D DFR87_09760 extracellular solute-binding protein K15495 wtpA; molybdate/tungstate transport system substrate-binding protein D DFR87_09755 ABC transporter permease subunit K15496 wtpB; molybdate/tungstate transport system permease protein D DFR87_10640 ATP-binding cassette domain-containing protein K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6] D DFR87_03885 ATP-binding cassette domain-containing protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D DFR87_12255 extracellular solute-binding protein K17311 treS; trehalose transport system substrate-binding protein D DFR87_12250 ABC transporter permease subunit K17312 treT; trehalose transport system permease protein D DFR87_12245 ABC transporter permease subunit K17313 treU; trehalose transport system permease protein D DFR87_12240 ATP-binding cassette domain-containing protein K17314 treV; trehalose transport system ATP-binding protein D DFR87_01575 energy-coupling factor transporter transmembrane protein EcfT K16785 ecfT; energy-coupling factor transport system permease protein C 02060 Phosphotransferase system (PTS) C 03070 Bacterial secretion system [PATH:mhk03070] D DFR87_06400 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D DFR87_10575 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D DFR87_09875 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D DFR87_02550 translocase K03116 tatA; sec-independent protein translocase protein TatA D DFR87_02555 tatA; twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA D DFR87_02545 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC B B 09132 Signal transduction C 02020 Two-component system [PATH:mhk02020] D DFR87_04295 CoA ester lyase K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34] D DFR87_06295 triphosphoribosyl-dephospho-CoA synthase K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52] D DFR87_07130 malate dehydrogenase K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D DFR87_00040 malate dehydrogenase K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D DFR87_10645 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D DFR87_03805 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D DFR87_03020 acetyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04160 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04375 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05445 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05450 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_10455 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_12260 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:mhk02024] D DFR87_10240 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D DFR87_10245 aminodeoxychorismate/anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D DFR87_01140 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D DFR87_10630 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D DFR87_07525 PKD domain-containing protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D DFR87_09360 hypothetical protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D DFR87_09365 ABC transporter permease subunit K02033 ABC.PE.P; peptide/nickel transport system permease protein D DFR87_11605 ABC transporter permease subunit K02033 ABC.PE.P; peptide/nickel transport system permease protein D DFR87_03970 ABC transporter permease subunit K02033 ABC.PE.P; peptide/nickel transport system permease protein D DFR87_07520 ABC transporter permease subunit K02033 ABC.PE.P; peptide/nickel transport system permease protein D DFR87_11600 peptide ABC transporter permease K02034 ABC.PE.P1; peptide/nickel transport system permease protein D DFR87_07515 ABC transporter permease subunit K02034 ABC.PE.P1; peptide/nickel transport system permease protein D DFR87_03965 ABC transporter permease subunit K02034 ABC.PE.P1; peptide/nickel transport system permease protein D DFR87_09370 ABC transporter permease subunit K02034 ABC.PE.P1; peptide/nickel transport system permease protein D DFR87_11595 ATP-binding cassette domain-containing protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D DFR87_07510 ATP-binding cassette domain-containing protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D DFR87_03960 ATP-binding cassette domain-containing protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D DFR87_06400 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D DFR87_10575 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D DFR87_09875 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D DFR87_01580 acid phosphatase K01114 plc; phospholipase C [EC:3.1.4.3] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis C 02040 Flagellar assembly C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D DFR87_10335 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism [PATH:mhk04980] D DFR87_10745 cob(I)yrinic acid a,c-diamide adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D DFR87_08810 cob(I)yrinic acid a,c-diamide adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D DFR87_08205 meaB; methylmalonyl Co-A mutase-associated GTPase MeaB K07588 MMAA; GTPase [EC:3.6.5.-] C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance C 01502 Vancomycin resistance C 01503 Cationic antimicrobial peptide (CAMP) resistance B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:mhk01000] C 01001 Protein kinases [BR:mhk01001] D DFR87_07410 Kae1-associated kinase Bud32 K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1] D DFR87_03010 serine protein kinase RIO K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] D DFR87_05645 serine/threonine protein kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1] C 01009 Protein phosphatases and associated proteins [BR:mhk01009] D DFR87_03030 translation initiation factor IF-2 subunit beta K03238 EIF2S2; translation initiation factor 2 subunit 2 D DFR87_06755 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] C 01002 Peptidases and inhibitors [BR:mhk01002] D DFR87_08035 peptidase A24 K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D DFR87_09385 pyroglutamyl-peptidase I K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3] D DFR87_11935 GMP synthase subunit A K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D DFR87_05820 GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D DFR87_08595 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D DFR87_08600 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D DFR87_10695 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D DFR87_13075 CPBP family intramembrane metalloprotease K07052 K07052; CAAX protease family protein D DFR87_05300 peptidase M1 K01256 pepN; aminopeptidase N [EC:3.4.11.2] D DFR87_02650 leucyl aminopeptidase K13722 trf2_3; tricorn protease interacting factor F2/3 [EC:3.4.11.-] D DFR87_02070 ArgE/DapE family deacylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D DFR87_07855 type II methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D DFR87_04555 carboxypeptidase M32 K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19] D DFR87_01115 M48 family metalloprotease K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D DFR87_05705 htpX; zinc metalloprotease HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D DFR87_11965 prolyl oligopeptidase family serine peptidase K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26] D DFR87_12545 hypothetical protein K13280 SEC11; signal peptidase I [EC:3.4.21.89] D DFR87_10350 signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89] D DFR87_00350 penicillin acylase K01434 pac; penicillin G amidase [EC:3.5.1.11] D DFR87_06600 psmA; archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D DFR87_06825 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D DFR87_08230 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D DFR87_03170 arginase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5] D DFR87_09390 hypothetical protein K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D DFR87_05585 gamma-glutamyltransferase family protein K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D DFR87_08460 TldD/PmbA family protein K03592 pmbA; PmbA protein D DFR87_04200 TldD/PmbA family protein K03592 pmbA; PmbA protein D DFR87_08465 TldD/PmbA family protein K03568 tldD; TldD protein D DFR87_04205 TldD/PmbA family protein K03568 tldD; TldD protein C 01003 Glycosyltransferases [BR:mhk01003] D DFR87_07800 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase K01001 ALG7; UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [EC:2.7.8.15] D DFR87_09600 peptide transporter K07151 STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18] D DFR87_09805 glycosyltransferase K02359 EGH; beta-1,4-mannosyltransferase [EC:2.4.1.-] D DFR87_11805 glycosyltransferase K00703 glgA; starch synthase [EC:2.4.1.21] C 01005 Lipopolysaccharide biosynthesis proteins C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:mhk01011] D DFR87_01055 undecaprenyl-diphosphate phosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] C 01004 Lipid biosynthesis proteins [BR:mhk01004] D DFR87_01075 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D DFR87_08130 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D DFR87_09855 SDR family oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D DFR87_12270 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_12345 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_05465 AMP-binding protein K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D DFR87_11685 CoA-binding protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D DFR87_01140 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D DFR87_10630 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:mhk01006] D DFR87_07795 polyprenyl synthetase family protein K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D DFR87_03200 polyprenyl synthetase family protein K21268 gdS-2; hexaprenyl diphosphate synthase [EC:2.5.1.82] D DFR87_06350 phytoene/squalene synthase family protein K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32] D DFR87_08005 ubiA; 4-hydroxybenzoate octaprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] D DFR87_08485 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] C 01007 Amino acid related enzymes [BR:mhk01007] D DFR87_07825 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D DFR87_07710 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D DFR87_07560 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D DFR87_08100 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D DFR87_10095 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D DFR87_08945 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D DFR87_06525 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D DFR87_10260 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D DFR87_02660 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D DFR87_08805 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D DFR87_07655 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D DFR87_05795 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D DFR87_06820 histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D DFR87_07470 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D DFR87_08745 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D DFR87_08905 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D DFR87_10805 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D DFR87_10610 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D DFR87_04150 alanyl-tRNA editing protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D DFR87_07865 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D DFR87_07870 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D DFR87_10255 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D DFR87_08795 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D DFR87_05965 acetylornithine/succinylornithine family transaminase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124] D DFR87_05425 acetyl ornithine aminotransferase family protein K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D DFR87_05740 hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:mhk03000] D DFR87_06885 dcm; DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D DFR87_10020 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D DFR87_03185 AsnC family transcriptional regulator K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA D DFR87_05980 AsnC family transcriptional regulator K06154 lysM; Lrp/AsnC family transcriptional regulator, involved in the regulation of lysine biosynthesis D DFR87_12430 MarR family transcriptional regulator K15973 mhqR; MarR family transcriptional regulator, 2-MHQ and catechol-resistance regulon repressor D DFR87_03590 transcriptional repressor K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator D DFR87_01085 metalloregulator ArsR/SmtB family transcription factor K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor D DFR87_01040 metalloregulator ArsR/SmtB family transcription factor K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor D DFR87_05620 ArsR family transcriptional regulator K22043 czrA; ArsR family transcriptional regulator, zinc-responsive transcriptional repressor D DFR87_07615 transcriptional regulator K22206 thiR; XRE family transcriptional regulator, thiamine biosynthesis regulator D DFR87_03320 PadR family transcriptional regulator K10947 K10947; PadR family transcriptional regulator D DFR87_08415 MarR family transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D DFR87_08165 metal-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D DFR87_08445 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D DFR87_07370 winged helix-turn-helix transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator D DFR87_04310 TrmB family transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator D DFR87_11490 LysR family transcriptional regulator K02019 modE; molybdate transport system regulatory protein D DFR87_01855 CRISPR locus-related DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3 D DFR87_10035 helix-turn-helix domain-containing protein K07728 K07728; putative transcriptional regulator D DFR87_10720 helix-turn-helix domain-containing protein K07731 K07731; putative transcriptional regulator D DFR87_08470 ribbon-helix-helix protein, CopG family K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator D DFR87_04945 4Fe-4S binding protein K19339 nosR; NosR/NirI family transcriptional regulator, nitrous oxide reductase regulator D DFR87_12335 tenA; thiaminase II K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2] C 03021 Transcription machinery [BR:mhk03021] D DFR87_07490 transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D DFR87_10000 transcription initiation factor IIB family protein K03124 TFIIB; transcription initiation factor TFIIB D DFR87_10020 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D DFR87_06880 tfe; transcription factor E K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha D DFR87_09230 DEAD/DEAH box helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] D DFR87_07335 DNA-binding protein K15171 SUPT4H1; transcription elongation factor SPT4 D DFR87_10585 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5 D DFR87_09680 GTPase K24104 GPN; GPN-loop GTPase D DFR87_07160 NusA-like transcription termination signal-binding factor K02600 nusA; transcription termination/antitermination protein NusA D DFR87_07145 rpoA1; DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6] D DFR87_07150 rpoA2; DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6] D DFR87_07140 DNA-directed RNA polymerase subunit B K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6] D DFR87_07745 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6] D DFR87_07330 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6] D DFR87_06660 DNA-directed RNA polymerase subunit F K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6] D DFR87_06835 DNA-directed RNA polymerase subunit G K03052 rpoG; DNA-directed RNA polymerase subunit G [EC:2.7.7.6] D DFR87_07135 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6] D DFR87_10310 DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6] D DFR87_09270 DNA-directed RNA polymerase subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6] D DFR87_07765 DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6] D DFR87_07480 DNA-directed RNA polymerase subunit P K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6] D DFR87_07240 RNA polymerase Rpo13 K00960 rpo13; DNA-directed RNA polymerase subunit 13 [EC:2.7.7.6] D DFR87_08730 DNA-directed RNA polymerase subunit M K03057 tfs; transcription factor S D DFR87_09280 transcription factor S K03057 tfs; transcription factor S C 03019 Messenger RNA biogenesis [BR:mhk03019] D DFR87_07335 DNA-binding protein K15171 SUPT4H1; transcription elongation factor SPT4 D DFR87_10585 transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5 D DFR87_05770 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D DFR87_07350 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D DFR87_07680 mRNA surveillance protein pelota K06965 PELO; protein pelota D DFR87_02635 prf1; peptide chain release factor 1 K03265 ETF1; peptide chain release factor subunit 1 D DFR87_07180 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha D DFR87_02940 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha D DFR87_09265 RNA-binding protein K07573 CSL4; exosome complex component CSL4 D DFR87_06590 RNA-binding protein K03679 RRP4; exosome complex component RRP4 D DFR87_06585 exosome complex exonuclease Rrp41 K11600 RRP41; exosome complex component RRP41 D DFR87_06580 exosome complex protein Rrp42 K12589 RRP42; exosome complex component RRP42 D DFR87_11245 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D DFR87_10335 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 03041 Spliceosome [BR:mhk03041] D DFR87_02935 ZPR1 zinc finger domain-containing protein K06874 ZPR1; zinc finger protein ZPR1 C 03011 Ribosome [BR:mhk03011] D DFR87_06635 30S ribosomal protein S3ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae D DFR87_06455 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e D DFR87_07315 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e D DFR87_05950 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e D DFR87_06785 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e D DFR87_10540 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e D DFR87_07425 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e D DFR87_07365 30S ribosomal protein S25e K02975 RP-S25e; small subunit ribosomal protein S25e D DFR87_08900 30S ribosomal protein S26e K02976 RP-S26e; small subunit ribosomal protein S26e D DFR87_09610 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e D DFR87_07420 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D DFR87_07110 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e D DFR87_10055 30S ribosomal protein S30e K02983 RP-S30e; small subunit ribosomal protein S30e D DFR87_06510 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e D DFR87_07820 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D DFR87_09255 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e D DFR87_07255 50S ribosomal protein L14e K02875 RP-L14e; large subunit ribosomal protein L14e D DFR87_06620 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e D DFR87_07750 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e D DFR87_06425 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e D DFR87_06665 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e D DFR87_07115 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e D DFR87_07155 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e D DFR87_10555 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e D DFR87_06430 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e D DFR87_06385 50S ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e D DFR87_06685 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e D DFR87_06575 50S ribosomal protein L37ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae D DFR87_10550 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e D DFR87_05805 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D DFR87_09605 50S ribosomal protein L44e K02929 RP-L44e; large subunit ribosomal protein L44e D DFR87_07770 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D DFR87_06485 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D DFR87_07735 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D DFR87_06415 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D DFR87_07175 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D DFR87_06440 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D DFR87_07760 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D DFR87_07185 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D DFR87_07740 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D DFR87_07165 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D DFR87_07730 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D DFR87_06445 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D DFR87_07300 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D DFR87_06470 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D DFR87_06495 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D DFR87_10595 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D DFR87_06500 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D DFR87_06515 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D DFR87_06450 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D DFR87_06435 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D DFR87_10600 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D DFR87_10590 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D DFR87_07755 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D DFR87_06465 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D DFR87_06405 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D DFR87_06420 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D DFR87_06490 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D DFR87_06505 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D DFR87_06460 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D DFR87_06480 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D DFR87_06410 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D DFR87_10605 50S ribosomal protein P1 K02869 RP-L12; large subunit ribosomal protein L12 D DFR87_10565 50S ribosomal protein L18a K02944 RP-LX; large subunit ribosomal protein LX D DFR87_09820 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D DFR87_09815 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:mhk03009] D DFR87_10050 C/D box methylation guide ribonucleoprotein complex aNOP56 subunit K14564 NOP56; nucleolar protein 56 D DFR87_09620 RNA-protein complex protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3 D DFR87_03495 16S rRNA methyltransferase K14568 EMG1; rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260] D DFR87_03005 RNA-processing protein K06961 KRR1; ribosomal RNA assembly protein D DFR87_03010 serine protein kinase RIO K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] D DFR87_05645 serine/threonine protein kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1] D DFR87_07590 AAA family ATPase K18532 AK6; adenylate kinase [EC:2.7.4.3] D DFR87_06775 ribosome biogenesis/translation initiation ATPase RLI K06174 ABCE1; ATP-binding cassette, sub-family E, member 1 D DFR87_08630 GTP-binding protein K06943 NOG1; nucleolar GTP-binding protein D DFR87_06475 ribonuclease P protein subunit K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D DFR87_06605 ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D DFR87_06610 hypothetical protein K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D DFR87_08300 GTP-binding protein K06947 GRC3; polynucleotide 5'-hydroxyl-kinase GRC3/NOL9 [EC:2.7.1.-] D DFR87_10560 translation initiation factor IF-6 K03264 EIF6; translation initiation factor 6 D DFR87_03040 NMD protein affecting ribosome stability and mRNA decay K07562 NMD3; 60S ribosomal export protein NMD3 D DFR87_06595 ribosome assembly factor SBDS K14574 SDO1; ribosome maturation protein SDO1 D DFR87_05770 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D DFR87_07350 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D DFR87_10045 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase K04795 flpA; fibrillarin-like pre-rRNA processing protein D DFR87_07820 50S ribosomal protein L7ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D DFR87_07160 NusA-like transcription termination signal-binding factor K02600 nusA; transcription termination/antitermination protein NusA D DFR87_06650 16S ribosomal RNA methyltransferase A K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D DFR87_10505 SAM-dependent methyltransferase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D DFR87_02645 RsmB/NOP family class I SAM-dependent RNA methyltransferase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D DFR87_07985 RsmB/NOP family class I SAM-dependent RNA methyltransferase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D DFR87_07270 methyltransferase K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172] D DFR87_06085 rimI; ribosomal-protein-alanine N-acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D DFR87_07685 GNAT family N-acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D DFR87_11245 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D DFR87_06870 GTP-binding protein K03665 hflX; GTPase D DFR87_08440 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D DFR87_03485 RNA-binding protein K07574 yhbY; RNA-binding protein D DFR87_06625 ychF; redox-regulated ATPase YchF K06942 ychF; ribosome-binding ATPase C 03016 Transfer RNA biogenesis [BR:mhk03016] D DFR87_06475 ribonuclease P protein subunit K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D DFR87_06605 ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D DFR87_06610 hypothetical protein K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D DFR87_03490 RNAse P, Rpr2/Rpp21 subunit K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5] D DFR87_09705 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11] D DFR87_09900 RNA-splicing ligase RtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8] D DFR87_06365 archease K24956 ZBTB8OS; protein archease D DFR87_07180 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha D DFR87_02940 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha D DFR87_07825 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D DFR87_08905 proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D DFR87_06525 isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D DFR87_02660 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D DFR87_08805 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D DFR87_08945 methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D DFR87_10095 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D DFR87_07655 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D DFR87_10610 alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D DFR87_04150 alanyl-tRNA editing protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D DFR87_07470 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D DFR87_10805 threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D DFR87_08745 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D DFR87_08100 cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D DFR87_10260 valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D DFR87_06820 histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D DFR87_07865 phenylalanine--tRNA ligase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D DFR87_07870 phenylalanine--tRNA ligase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D DFR87_07710 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D DFR87_07560 tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D DFR87_03555 D-aminoacyl-tRNA deacylase K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96] D DFR87_07545 alanyl-tRNA editing protein AlaX K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-] D DFR87_03385 HIT domain-containing protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D DFR87_03025 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5] D DFR87_10030 tRNA (guanine(26)-N(2))-dimethyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216] D DFR87_02725 class I SAM-dependent methyltransferase family protein K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D DFR87_07380 methyltransferase domain-containing protein K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220] D DFR87_09970 4-demethylwyosine synthase TYW1 K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44] D DFR87_08640 hypothetical protein K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282] D DFR87_07265 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D DFR87_07260 tRNA pseudouridine synthase A K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D DFR87_05790 truD; tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27] D DFR87_07410 Kae1-associated kinase Bud32 K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1] D DFR87_07415 kae1; N(6)-L-threonylcarbamoyladenine synthase Kae1 K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234] D DFR87_08440 threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D DFR87_08260 hypothetical protein K06963 TAN1; tRNA acetyltransferase TAN1 D DFR87_09725 CCA tRNA nucleotidyltransferase K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72] D DFR87_06815 ribonuclease BN K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16] D DFR87_07450 endA; tRNA-intron lyase K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16] D DFR87_09720 thpR; RNA 2',3'-cyclic phosphodiesterase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58] D DFR87_05795 aspS; aspartate--tRNA(Asn) ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D DFR87_06640 RNA methyltransferase K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-] D DFR87_07005 NOL1/NOP2/sun family putative RNA methylase K22901 trm4; tRNA (cytosine40_48-C5)-methyltransferase [EC:2.1.1.-] D DFR87_11375 tRNA (guanine-N1)-methyltransferase K15566 trm10; tRNA (adenine9-N1/guanine9-N1)-methyltransferase [EC:2.1.1.218 2.1.1.221] D DFR87_09690 RNA methyltransferase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213] D DFR87_06875 tRNA methyltransferase K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206] D DFR87_11280 adenine nucleotide alpha hydrolase family protein K21947 ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15] D DFR87_04245 response regulator SirA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D DFR87_00535 response regulator SirA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D DFR87_10905 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D DFR87_04915 queC; 7-cyano-7-deazaguanine synthase QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D DFR87_02875 6-pyruvoyl tetrahydrobiopterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D DFR87_08635 radical SAM protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D DFR87_06845 tgtA; tRNA guanosine(15) transglycosylase TgtA K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48] D DFR87_06960 DUF1743 domain-containing protein K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22] D DFR87_05515 GNAT family N-acetyltransferase K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193] D DFR87_05570 GNAT family N-acetyltransferase K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193] C 03012 Translation factors [BR:mhk03012] D DFR87_03015 translation initiation factor IF-1A K03236 EIF1A; translation initiation factor 1A D DFR87_07485 yciH; stress response translation initiation inhibitor YciH K03113 EIF1; translation initiation factor 1 D DFR87_09615 translation initiation factor IF-2 subunit alpha K03237 EIF2S1; translation initiation factor 2 subunit 1 D DFR87_03030 translation initiation factor IF-2 subunit beta K03238 EIF2S2; translation initiation factor 2 subunit 2 D DFR87_07320 translation initiation factor IF-2 subunit gamma K03242 EIF2S3; translation initiation factor 2 subunit 3 D DFR87_09880 translation initiation factor IF-5A K03263 EIF5A; translation initiation factor 5A D DFR87_07125 infB; translation initiation factor IF-2 K03243 EIF5B; translation initiation factor 5B D DFR87_10560 translation initiation factor IF-6 K03264 EIF6; translation initiation factor 6 D DFR87_07180 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha D DFR87_02940 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha D DFR87_05775 elongation factor 1-beta K03232 EEF1B; elongation factor 1-beta D DFR87_06550 elongation factor EF-2 K03234 EEF2; elongation factor 2 D DFR87_09260 dph2; diphthamide biosynthesis enzyme Dph2 K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108] D DFR87_02635 prf1; peptide chain release factor 1 K03265 ETF1; peptide chain release factor subunit 1 D DFR87_06645 methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D DFR87_05785 peptidyl-tRNA hydrolase K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29] C 03110 Chaperones and folding catalysts [BR:mhk03110] D DFR87_06805 thermosome subunit K22447 cct; archaeal chaperonin D DFR87_10120 thermosome subunit K22447 cct; archaeal chaperonin D DFR87_02025 Hsp20/alpha crystallin family protein K13993 HSP20; HSP20 family protein D DFR87_02930 Hsp20 family protein K13993 HSP20; HSP20 family protein D DFR87_12285 Hsp20 family protein K13993 HSP20; HSP20 family protein D DFR87_10570 prefoldin subunit alpha K04797 pfdA; prefoldin alpha subunit D DFR87_06560 prefoldin subunit beta K04798 pfdB; prefoldin beta subunit D DFR87_06740 peptidylprolyl isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8] D DFR87_10635 trxA; thioredoxin K03671 TXN; thioredoxin D DFR87_03545 trxA; thioredoxin K03671 TXN; thioredoxin C 04131 Membrane trafficking [BR:mhk04131] D DFR87_07120 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D DFR87_05770 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D DFR87_07350 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D DFR87_11830 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D DFR87_07180 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha D DFR87_02940 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha C 04121 Ubiquitin system [BR:mhk04121] D DFR87_05805 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D DFR87_07420 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D DFR87_10055 30S ribosomal protein S30e K02983 RP-S30e; small subunit ribosomal protein S30e C 03051 Proteasome [BR:mhk03051] D DFR87_06600 psmA; archaeal proteasome endopeptidase complex subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D DFR87_06825 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D DFR87_08230 psmB; archaeal proteasome endopeptidase complex subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D DFR87_06860 pan; proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit C 03032 DNA replication proteins [BR:mhk03032] D DFR87_07305 reverse transcriptase-like protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D DFR87_07235 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D DFR87_07285 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen D DFR87_09660 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D DFR87_05760 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D DFR87_06060 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D DFR87_06885 dcm; DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D DFR87_09620 RNA-protein complex protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3 D DFR87_06555 multidrug MFS transporter K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] D DFR87_07705 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D DFR87_06975 AAA family ATPase K10725 cdc6A; archaeal cell division control protein 6 D DFR87_03250 AAA family ATPase K10725 cdc6A; archaeal cell division control protein 6 D DFR87_08255 ORC1-type DNA replication protein K10725 cdc6A; archaeal cell division control protein 6 D DFR87_08270 AAA domain-containing protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D DFR87_09655 priS; DNA primase small subunit PriS K02683 priS; DNA primase small subunit [EC:2.7.7.102] D DFR87_08950 DNA primase regulatory subunit PriL K18882 priL; DNA primase large subunit D DFR87_08265 hypothetical protein K09723 ginS; DNA replication factor GINS D DFR87_03045 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D DFR87_11550 DNA polymerase II K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D DFR87_08975 DNA-directed DNA polymerase I K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D DFR87_08240 replication factor C large subunit K04800 rfcL; replication factor C large subunit D DFR87_08235 replication factor C small subunit K04801 rfcS; replication factor C small subunit D DFR87_09885 DNA topoisomerase IV subunit A K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2] D DFR87_09890 DNA topoisomerase VI subunit B K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2] D DFR87_02330 type IA DNA topoisomerase K03169 topB; DNA topoisomerase III [EC:5.6.2.1] D DFR87_07355 rgy; reverse gyrase K03170 topG; reverse gyrase [EC:5.6.2.2 5.6.2.-] D DFR87_09920 rgy; reverse gyrase K03170 topG; reverse gyrase [EC:5.6.2.2 5.6.2.-] C 03036 Chromosome and associated proteins [BR:mhk03036] D DFR87_06885 dcm; DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D DFR87_06520 hypothetical protein K09142 SPOUT1; methyltransferase [EC:2.1.1.-] D DFR87_03830 AAA family ATPase K03496 parA; chromosome partitioning protein D DFR87_05650 AAA family ATPase K03496 parA; chromosome partitioning protein D DFR87_00910 AAA family ATPase K03496 parA; chromosome partitioning protein D DFR87_00655 P-loop NTPase K03496 parA; chromosome partitioning protein D DFR87_10515 tyrosine-type recombinase/integrase K04763 xerD; integrase/recombinase XerD D DFR87_07585 P-loop NTPase K03593 mrp; ATP-binding protein involved in chromosome partitioning C 03400 DNA repair and recombination proteins [BR:mhk03400] D DFR87_10810 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D DFR87_04000 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D DFR87_07935 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D DFR87_07235 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D DFR87_07285 pcn; proliferating cell nuclear antigen (pcna) K04802 PCNA; proliferating cell nuclear antigen D DFR87_09660 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D DFR87_05760 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D DFR87_06060 ATP-dependent DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D DFR87_09230 DEAD/DEAH box helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] D DFR87_06555 multidrug MFS transporter K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] D DFR87_08105 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D DFR87_01230 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D DFR87_08135 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D DFR87_11560 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D DFR87_03400 TIM barrel protein K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D DFR87_11925 endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7] D DFR87_03615 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50 D DFR87_03620 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11 D DFR87_01810 cas1b; type I-B CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1 D DFR87_12970 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1 D DFR87_07015 radA; DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA D DFR87_00820 endonuclease K03552 hjr; holliday junction resolvase [EC:3.1.21.10] D DFR87_08875 endonuclease K03552 hjr; holliday junction resolvase [EC:3.1.21.10] D DFR87_03625 DUF853 family protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase D DFR87_03610 hypothetical protein K25510 nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-] D DFR87_11885 DEAD/DEAH box helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4] D DFR87_11585 DEAD/DEAH box helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4] D DFR87_03785 DNA polymerase IV K04479 dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7] D DFR87_07250 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] D DFR87_07920 ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] D DFR87_09910 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] D DFR87_10080 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D DFR87_12040 hypothetical protein K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D DFR87_10160 hypothetical protein K22585 nreA; DNA repair protein NreA D DFR87_01255 hypothetical protein K22585 nreA; DNA repair protein NreA C 03029 Mitochondrial biogenesis [BR:mhk03029] D DFR87_06475 ribonuclease P protein subunit K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D DFR87_06605 ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D DFR87_06610 hypothetical protein K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D DFR87_07710 tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D DFR87_02660 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D DFR87_08805 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D DFR87_07470 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D DFR87_10095 arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D DFR87_03650 amidase K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D DFR87_09965 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D DFR87_07095 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D DFR87_09960 gatC; Asp-tRNA(Asn) amidotransferase subunit GatC K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D DFR87_07585 P-loop NTPase K03593 mrp; ATP-binding protein involved in chromosome partitioning D DFR87_08485 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:mhk02000] D DFR87_09760 extracellular solute-binding protein K15495 wtpA; molybdate/tungstate transport system substrate-binding protein D DFR87_09755 ABC transporter permease subunit K15496 wtpB; molybdate/tungstate transport system permease protein D DFR87_10640 ATP-binding cassette domain-containing protein K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6] D DFR87_11720 ABC transporter permease subunit K02050 ABC.SN.P; NitT/TauT family transport system permease protein D DFR87_11725 ATP-binding cassette domain-containing protein K02049 ABC.SN.A; NitT/TauT family transport system ATP-binding protein D DFR87_03885 ATP-binding cassette domain-containing protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D DFR87_12255 extracellular solute-binding protein K17311 treS; trehalose transport system substrate-binding protein D DFR87_12250 ABC transporter permease subunit K17312 treT; trehalose transport system permease protein D DFR87_12245 ABC transporter permease subunit K17313 treU; trehalose transport system permease protein D DFR87_12240 ATP-binding cassette domain-containing protein K17314 treV; trehalose transport system ATP-binding protein D DFR87_03890 extracellular solute-binding protein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D DFR87_03875 ABC transporter permease subunit K02025 ABC.MS.P; multiple sugar transport system permease protein D DFR87_07525 PKD domain-containing protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D DFR87_09360 hypothetical protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D DFR87_09365 ABC transporter permease subunit K02033 ABC.PE.P; peptide/nickel transport system permease protein D DFR87_11605 ABC transporter permease subunit K02033 ABC.PE.P; peptide/nickel transport system permease protein D DFR87_03970 ABC transporter permease subunit K02033 ABC.PE.P; peptide/nickel transport system permease protein D DFR87_07520 ABC transporter permease subunit K02033 ABC.PE.P; peptide/nickel transport system permease protein D DFR87_11600 peptide ABC transporter permease K02034 ABC.PE.P1; peptide/nickel transport system permease protein D DFR87_07515 ABC transporter permease subunit K02034 ABC.PE.P1; peptide/nickel transport system permease protein D DFR87_03965 ABC transporter permease subunit K02034 ABC.PE.P1; peptide/nickel transport system permease protein D DFR87_09370 ABC transporter permease subunit K02034 ABC.PE.P1; peptide/nickel transport system permease protein D DFR87_11595 ATP-binding cassette domain-containing protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D DFR87_07510 ATP-binding cassette domain-containing protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D DFR87_03960 ATP-binding cassette domain-containing protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D DFR87_02475 ABC transporter substrate-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D DFR87_08020 ABC transporter substrate-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D DFR87_02480 iron chelate uptake ABC transporter family permease subunit K02015 ABC.FEV.P; iron complex transport system permease protein D DFR87_02485 AAA family ATPase K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-] D DFR87_01575 energy-coupling factor transporter transmembrane protein EcfT K16785 ecfT; energy-coupling factor transport system permease protein D DFR87_01570 ATP-binding cassette domain-containing protein K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D DFR87_02690 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein D DFR87_02820 ABC transporter permease subunit K01992 ABC-2.P; ABC-2 type transport system permease protein D DFR87_12735 hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein D DFR87_04535 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein D DFR87_05280 ABC transporter permease subunit K01992 ABC-2.P; ABC-2 type transport system permease protein D DFR87_05545 ABC transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D DFR87_00410 ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein D DFR87_02695 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D DFR87_02815 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D DFR87_12575 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D DFR87_12730 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D DFR87_12810 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D DFR87_04530 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D DFR87_05285 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D DFR87_05540 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D DFR87_00405 ATP-binding cassette domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D DFR87_11090 FtsX-like permease family protein K02004 ABC.CD.P; putative ABC transport system permease protein D DFR87_11080 ATP-binding cassette domain-containing protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D DFR87_10390 sufC; Fe-S cluster assembly ATPase SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein D DFR87_12820 MFS transporter K03762 proP; MFS transporter, MHS family, proline/betaine transporter D DFR87_00215 MFS transporter K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter D DFR87_12185 MFS transporter K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter D DFR87_05525 MFS transporter K08178 JEN; MFS transporter, SHS family, lactate transporter D DFR87_11150 MFS transporter K08176 PHO84; MFS transporter, PHS family, inorganic phosphate transporter D DFR87_00450 MFS transporter K02575 NRT2; MFS transporter, NNP family, nitrate/nitrite transporter D DFR87_04105 MFS transporter K08223 fsr; MFS transporter, FSR family, fosmidomycin resistance protein D DFR87_01550 MFS transporter K08368 yaaU; MFS transporter, putative metabolite transport protein D DFR87_12120 MFS transporter K08368 yaaU; MFS transporter, putative metabolite transport protein D DFR87_01120 MFS transporter K08368 yaaU; MFS transporter, putative metabolite transport protein D DFR87_01515 MFS transporter K08368 yaaU; MFS transporter, putative metabolite transport protein D DFR87_00370 MFS transporter K08368 yaaU; MFS transporter, putative metabolite transport protein D DFR87_04110 MFS transporter K08369 ydjE; MFS transporter, putative metabolite:H+ symporter D DFR87_09800 MFS transporter K08369 ydjE; MFS transporter, putative metabolite:H+ symporter D DFR87_00945 MFS transporter K08369 ydjE; MFS transporter, putative metabolite:H+ symporter D DFR87_03870 MFS transporter K08369 ydjE; MFS transporter, putative metabolite:H+ symporter D DFR87_11255 VWA domain-containing protein K07114 yfbK; Ca-activated chloride channel homolog D DFR87_11610 VWA domain-containing protein K07114 yfbK; Ca-activated chloride channel homolog D DFR87_04770 VWA domain-containing protein K07114 yfbK; Ca-activated chloride channel homolog D DFR87_02415 mechanosensitive ion channel K03442 mscS; small conductance mechanosensitive channel D DFR87_09595 hypothetical protein K21449 ata; trimeric autotransporter adhesin D DFR87_00435 APC family permease K16238 eat; ethanolamine permease D DFR87_00555 cation diffusion facilitator family transporter K16264 czcD; cobalt-zinc-cadmium efflux system protein D DFR87_00805 hypothetical protein K07238 TC.ZIP; zinc transporter, ZIP family D DFR87_00065 L-lactate permease K03303 lutP; lactate permease D DFR87_11040 sodium:calcium antiporter K07301 yrbG; cation:H+ antiporter D DFR87_04780 sodium:calcium antiporter K07301 yrbG; cation:H+ antiporter D DFR87_11210 cation:proton antiporter K26730 napA; Na+:H+ antiporter D DFR87_04495 CBS domain-containing protein K03281 clcA; chloride channel protein, CIC family D DFR87_11990 HoxN/HupN/NixA family nickel/cobalt transporter K07241 hoxN; nickel/cobalt transporter (NiCoT) family protein D DFR87_08145 hypothetical protein K23675 fmnP; riboflavin transporter D DFR87_03705 hypothetical protein K22736 VIT; vacuolar iron transporter family protein D DFR87_04785 ferritin, CCC1 K22736 VIT; vacuolar iron transporter family protein D DFR87_08720 MarC family protein K05595 marC; multiple antibiotic resistance protein D DFR87_05105 arsenate reductase (azurin) small subunit K08355 aoxA; arsenite oxidase small subunit [EC:1.20.2.1 1.20.9.1] D DFR87_05070 molybdopterin dinucleotide-binding protein K08356 aoxB; arsenite oxidase large subunit [EC:1.20.2.1 1.20.9.1] D DFR87_06000 DUF87 domain-containing protein K25503 cedB; DNA import protein CedB D DFR87_06370 hypothetical protein K25504 cedA; DNA import protein CedA D DFR87_06375 hypothetical protein K25505 cedA1; DNA import protein CedA1 C 02044 Secretion system [BR:mhk02044] D DFR87_02985 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI D DFR87_07965 type II secretion system protein VirB K07332 flaI; archaeal flagellar protein FlaI D DFR87_12860 ATP-binding cassette domain-containing protein K07332 flaI; archaeal flagellar protein FlaI D DFR87_02995 flagellar assembly protein K07333 flaJ; archaeal flagellar protein FlaJ D DFR87_07960 hypothetical protein K07333 flaJ; archaeal flagellar protein FlaJ D DFR87_12855 secretion system protein K07333 flaJ; archaeal flagellar protein FlaJ D DFR87_08035 peptidase A24 K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D DFR87_06400 secY; preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY D DFR87_09875 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D DFR87_10575 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D DFR87_05945 hypothetical protein K03105 SRP19; signal recognition particle subunit SRP19 D DFR87_02550 translocase K03116 tatA; sec-independent protein translocase protein TatA D DFR87_02555 tatA; twin-arginine translocase TatA/TatE family subunit K03116 tatA; sec-independent protein translocase protein TatA D DFR87_02545 tatC; twin-arginine translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC C 02042 Bacterial toxins [BR:mhk02042] D DFR87_01580 acid phosphatase K01114 plc; phospholipase C [EC:3.1.4.3] C 02022 Two-component system C 02035 Bacterial motility proteins [BR:mhk02035] D DFR87_02985 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI D DFR87_07965 type II secretion system protein VirB K07332 flaI; archaeal flagellar protein FlaI D DFR87_12860 ATP-binding cassette domain-containing protein K07332 flaI; archaeal flagellar protein FlaI D DFR87_02995 flagellar assembly protein K07333 flaJ; archaeal flagellar protein FlaJ D DFR87_07960 hypothetical protein K07333 flaJ; archaeal flagellar protein FlaJ D DFR87_12855 secretion system protein K07333 flaJ; archaeal flagellar protein FlaJ D DFR87_08035 peptidase A24 K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:mhk04812] D DFR87_07775 amrB; AmmeMemoRadiSam system protein B K06990 MEMO1; MEMO1 family protein D DFR87_03830 AAA family ATPase K03496 parA; chromosome partitioning protein D DFR87_05650 AAA family ATPase K03496 parA; chromosome partitioning protein D DFR87_00910 AAA family ATPase K03496 parA; chromosome partitioning protein D DFR87_00655 P-loop NTPase K03496 parA; chromosome partitioning protein C 04147 Exosome [BR:mhk04147] D DFR87_10335 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D DFR87_10485 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D DFR87_11830 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D DFR87_11105 peroxiredoxin K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24] D DFR87_07180 tuf; translation elongation factor EF-1 subunit alpha K03231 EEF1A; elongation factor 1-alpha D DFR87_02940 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha D DFR87_06550 elongation factor EF-2 K03234 EEF2; elongation factor 2 D DFR87_05760 flap endonuclease-1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D DFR87_07420 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D DFR87_05770 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D DFR87_07350 CDC48 family AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase D DFR87_03385 HIT domain-containing protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D DFR87_01140 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D DFR87_10630 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D DFR87_00480 selenium-binding protein K17285 SELENBP1; methanethiol oxidase [EC:1.8.3.4] D DFR87_03020 acetyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04160 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_04375 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05445 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_05450 thiolase domain-containing protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_10455 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_12260 thiolase family protein K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D DFR87_06755 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D DFR87_06395 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D DFR87_08565 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D DFR87_08570 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D DFR87_10645 glnA; type I glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D DFR87_03805 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D DFR87_05745 hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D DFR87_03245 4a-hydroxytetrahydrobiopterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] D DFR87_10300 3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D DFR87_01520 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_10985 FAD-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08450 NAD(P)-binding protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_08650 FAD-dependent oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D DFR87_04740 electron transfer flavoprotein subunit alpha/FixB family protein K03522 fixB; electron transfer flavoprotein alpha subunit D DFR87_12690 electron transfer flavoprotein subunit alpha K03522 fixB; electron transfer flavoprotein alpha subunit D DFR87_08115 glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D DFR87_11485 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 02048 Prokaryotic defense system [BR:mhk02048] D DFR87_01810 cas1b; type I-B CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1 D DFR87_12970 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1 D DFR87_01770 cas2; CRISPR-associated endonuclease Cas2 K09951 cas2; CRISPR-associated protein Cas2 D DFR87_12975 cas2; CRISPR-associated endonuclease Cas2 K09951 cas2; CRISPR-associated protein Cas2 D DFR87_01830 cas3; CRISPR-associated helicase Cas3' K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] D DFR87_13055 cas4a; type I-A CRISPR-associated protein Cas4/Csa1 K19085 csa1; CRISPR-associated protein Csa1 D DFR87_01855 CRISPR locus-related DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3 D DFR87_01780 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D DFR87_12950 cas4; CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D DFR87_04210 hypothetical protein K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D DFR87_01960 cas6; CRISPR-associated endoribonuclease Cas6 K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] D DFR87_01815 hypothetical protein K19114 csh1; CRISPR-associated protein Csh1 D DFR87_01820 cas7b; type I-B CRISPR-associated protein Cas7/Csh2 K19115 csh2; CRISPR-associated protein Csh2 D DFR87_01825 cas5; CRISPR-associated protein Cas5 K19116 cas5h; CRISPR-associated protein Cas5h D DFR87_12985 hydrolase K07016 csm1; CRISPR-associated protein Csm1 D DFR87_12995 csm3; type III-A CRISPR-associated RAMP protein Csm3 K09002 csm3; CRISPR-associated protein Csm3 D DFR87_01910 CRISPR-associated RAMP protein K09002 csm3; CRISPR-associated protein Csm3 D DFR87_13040 hypothetical protein K19139 csm4; CRISPR-associated protein Csm4 D DFR87_12990 CRISPR-associated protein Csm5 K19140 csm5; CRISPR-associated protein Csm5 D DFR87_01225 CRISPR-associated DxTHG motif protein K19143 csx1; CRISPR-associated protein Csx1 D DFR87_06885 dcm; DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D DFR87_02270 type II toxin-antitoxin system RelE/ParE family toxin K06218 relE; mRNA interferase RelE/StbE D DFR87_00200 hypothetical protein K19164 ccdA; antitoxin CcdA D DFR87_07375 ribbon-helix-helix protein, CopG family K07746 parD1_3_4; antitoxin ParD1/3/4 D DFR87_01900 type II toxin-antitoxin system death-on-curing family toxin K07341 doc; death on curing protein D DFR87_07825 glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D DFR87_03450 DNA-binding protein K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules C 01504 Antimicrobial resistance genes C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:mhk03100] D DFR87_10740 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D DFR87_10755 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D DFR87_06970 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D DFR87_10090 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D DFR87_10620 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D DFR87_08980 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D DFR87_06910 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D DFR87_09295 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D DFR87_07810 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D DFR87_07280 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D DFR87_10430 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D DFR87_10435 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D DFR87_02225 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D DFR87_06315 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D DFR87_09105 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D DFR87_07640 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D DFR87_06095 tRNA-His K14226 tRNA-His; tRNA His D DFR87_09640 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D DFR87_06670 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D DFR87_08320 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D DFR87_02640 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D DFR87_09830 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D DFR87_06700 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D DFR87_10625 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D DFR87_10440 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D DFR87_06750 tRNA-Ile K14230 tRNA-Met; tRNA Met D DFR87_06080 tRNA-Met K14230 tRNA-Met; tRNA Met D DFR87_10415 tRNA-Met K14230 tRNA-Met; tRNA Met D DFR87_06330 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D DFR87_09740 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D DFR87_10725 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D DFR87_07815 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D DFR87_07190 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D DFR87_07275 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D DFR87_08330 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D DFR87_06695 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D DFR87_10410 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D DFR87_07065 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D DFR87_10830 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D DFR87_07645 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D DFR87_06675 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D DFR87_06895 tRNA-Val K14237 tRNA-Val; tRNA Val D DFR87_06705 tRNA-Val K14237 tRNA-Val; tRNA Val D DFR87_05660 tRNA-Val K14237 tRNA-Val; tRNA Val D DFR87_09820 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D DFR87_09815 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D DFR87_02765 2Fe-2S iron-sulfur cluster binding domain-containing protein K03518 coxS; aerobic carbon-monoxide dehydrogenase small subunit [EC:1.2.5.3] D DFR87_02760 xanthine dehydrogenase family protein subunit M K03519 coxM; aerobic carbon-monoxide dehydrogenase medium subunit [EC:1.2.5.3] D DFR87_02615 molybdopterin-dependent oxidoreductase K03520 coxL; aerobic carbon-monoxide dehydrogenase large subunit [EC:1.2.5.3] D DFR87_04810 molybdopterin-dependent oxidoreductase K03520 coxL; aerobic carbon-monoxide dehydrogenase large subunit [EC:1.2.5.3] D DFR87_05415 molybdopterin-dependent oxidoreductase K03520 coxL; aerobic carbon-monoxide dehydrogenase large subunit [EC:1.2.5.3] D DFR87_05850 molybdopterin-dependent oxidoreductase K03520 coxL; aerobic carbon-monoxide dehydrogenase large subunit [EC:1.2.5.3] D DFR87_12465 molybdopterin-dependent oxidoreductase K03520 coxL; aerobic carbon-monoxide dehydrogenase large subunit [EC:1.2.5.3] D DFR87_10730 indolepyruvate ferredoxin oxidoreductase subunit alpha K00179 iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8] D DFR87_10735 pyruvate ferredoxin oxidoreductase K00180 iorB; indolepyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.8] D DFR87_01380 TenA family transcriptional regulator K06137 pqqC; pyrroloquinoline-quinone synthase [EC:1.3.3.11] D DFR87_05440 acyl-CoA dehydrogenase K18244 mmgC; acyl-CoA dehydrogenase [EC:1.3.99.-] D DFR87_12695 FAD-dependent oxidoreductase K00313 fixC; electron transfer flavoprotein-quinone oxidoreductase [EC:1.5.5.-] D DFR87_04745 FAD-dependent oxidoreductase K00313 fixC; electron transfer flavoprotein-quinone oxidoreductase [EC:1.5.5.-] D DFR87_08085 CoA-disulfide reductase K18367 CoADR; CoA-dependent NAD(P)H sulfur oxidoreductase [EC:1.8.1.18] D DFR87_03315 msrA; peptide-methionine (S)-S-oxide reductase MsrA K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D DFR87_12015 redoxin domain-containing protein K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D DFR87_03640 redoxin domain-containing protein K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D DFR87_04465 redoxin domain-containing protein K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25] D DFR87_01525 pirin family protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24] D DFR87_04335 merA; mercury(II) reductase K00520 merA; mercuric reductase [EC:1.16.1.1] D DFR87_03470 SidA/IucD/PvdA family monooxygenase K21567 fnr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D DFR87_07075 radical SAM protein K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5] D DFR87_08500 amrS; AmmeMemoRadiSam system radical SAM enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D DFR87_07630 protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] D DFR87_09985 diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98] D DFR87_09895 deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46] D DFR87_08955 CDP-alcohol phosphatidyltransferase family protein K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39] D DFR87_01180 ADP-ribose-binding protein K23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106] D DFR87_00900 sixA; phosphohistidine phosphatase SixA K08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-] D DFR87_08350 TatD family deoxyribonuclease K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D DFR87_09765 TatD family deoxyribonuclease K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D DFR87_03675 DNA-binding protein K16640 ssh7; DNA-binding protein 7 [EC:3.1.27.-] D DFR87_10295 N-glycosylase/DNA lyase K03653 K03653; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] D DFR87_11705 deaminase K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10] D DFR87_03075 AAA domain-containing protein K03924 moxR; MoxR-like ATPase [EC:3.6.3.-] D DFR87_06995 hypothetical protein K22205 E3.13.2.3; S-adenosyl-L-methionine hydrolase (adenosine-forming) [EC:3.13.2.3] D DFR87_01955 uvsE; UV DNA damage repair endonuclease UvsE K13281 uvsE; UV DNA damage endonuclease [EC:3.-.-.-] D DFR87_03635 NAD(P)H-hydrate dehydratase K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6] D DFR87_03795 RNA 3'-terminal phosphate cyclase K01974 RTCA; RNA 3'-terminal phosphate cyclase (ATP) [EC:6.5.1.4] C 99981 Carbohydrate metabolism D DFR87_11305 sfsA; DNA/RNA nuclease SfsA K06206 sfsA; sugar fermentation stimulation protein A D DFR87_04835 acetoin utilization protein AcuC K04768 acuC; acetoin utilization protein AcuC D DFR87_10960 histone deacetylase family protein K04768 acuC; acetoin utilization protein AcuC D DFR87_11410 lactate utilization protein K00782 lldG; L-lactate dehydrogenase complex protein LldG C 99982 Energy metabolism D DFR87_12055 fdhD; formate dehydrogenase accessory sulfurtransferase FdhD K02379 fdhD; FdhD protein D DFR87_08340 oxidase K16934 doxC; terminal oxidase subunit D DFR87_04670 cytochrome bc complex cytochrome b subunit K15879 narC; cytochrome b-561 D DFR87_04735 electron transfer flavoprotein subunit alpha K03521 fixA; electron transfer flavoprotein beta subunit D DFR87_12700 4Fe-4S ferredoxin K03855 fixX; ferredoxin like protein D DFR87_04750 4Fe-4S dicluster domain-containing protein K03855 fixX; ferredoxin like protein C 99983 Lipid metabolism C 99984 Nucleotide metabolism C 99985 Amino acid metabolism C 99986 Glycan metabolism C 99987 Cofactor metabolism D DFR87_08385 mobB; molybdopterin-guanine dinucleotide biosynthesis protein B K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein C 99988 Secondary metabolism C 99999 Others D DFR87_05485 DoxX family membrane protein K15977 K15977; putative oxidoreductase B B 09192 Unclassified: genetic information processing C 99973 Transcription D DFR87_06865 TIGR00270 family protein K03627 MBF1; putative transcription factor D DFR87_09925 albA; DNA-binding protein Alba K03622 ssh10b; archaea-specific DNA-binding protein D DFR87_09915 DNA-binding protein K03622 ssh10b; archaea-specific DNA-binding protein D DFR87_06680 RNA-binding protein K04796 RUXX; small nuclear ribonucleoprotein D DFR87_05625 Sm ribonucleo K04796 RUXX; small nuclear ribonucleoprotein D DFR87_03420 transcriptional regulator K07743 K07743; transcriptional regulator D DFR87_07910 CBS domain-containing protein K07744 K07744; transcriptional regulator C 99974 Translation D DFR87_06655 DUF655 domain-containing protein K07572 K07572; putative nucleotide binding protein D DFR87_10710 MBL fold metallo-hydrolase K07577 K07577; putative mRNA 3-end processing factor D DFR87_06065 MBL fold metallo-hydrolase K07577 K07577; putative mRNA 3-end processing factor D DFR87_03410 methyltransferase K07579 K07579; putative methylase D DFR87_05780 DUF1610 domain-containing protein K07580 K07580; Zn-ribbon RNA-binding protein D DFR87_06615 exosome protein K07581 K07581; RNA-binding protein C 99975 Protein processing D DFR87_00500 hypothetical protein K03187 ureE; urease accessory protein D DFR87_00495 urease accessory protein UreF K03188 ureF; urease accessory protein D DFR87_00490 ureG; urease accessory protein UreG K03189 ureG; urease accessory protein D DFR87_07725 AIR synthase K07388 K07388; hydrogenase expression/formation protein D DFR87_06855 pseudouridine synthase K07398 K07398; conserved protein with predicted RNA binding PUA domain D DFR87_02670 SelT/SelW/SelH family protein K07401 K07401; selenoprotein W-related protein D DFR87_11620 XdhC family protein K07402 xdhC; xanthine dehydrogenase accessory factor C 99976 Replication and repair D DFR87_06140 DUF1156 domain-containing protein K07445 K07445; putative DNA methylase D DFR87_09310 IS607 family transposase K07450 K07450; putative resolvase D DFR87_11070 IS607 family transposase K07450 K07450; putative resolvase D DFR87_10795 endonuclease III domain-containing protein K07457 K07457; endonuclease III related protein D DFR87_03775 AAA family ATPase K07472 TIP49; TBP-interacting protein D DFR87_02295 IS110 family transposase K07486 K07486; transposase D DFR87_03260 tnpA; IS200/IS605 family transposase K07491 rayT; REP-associated tyrosine transposase D DFR87_01155 tnpA; IS200/IS605 family transposase K07491 rayT; REP-associated tyrosine transposase D DFR87_03085 tnpA; IS200/IS605 family transposase K07491 rayT; REP-associated tyrosine transposase D DFR87_04755 hypothetical protein K07493 K07493; putative transposase D DFR87_09485 IS256 family transposase K07493 K07493; putative transposase D DFR87_09515 IS256 family transposase K07493 K07493; putative transposase D DFR87_09530 IS256 family transposase K07493 K07493; putative transposase D DFR87_00840 IS256 family transposase K07493 K07493; putative transposase D DFR87_06120 IS256 family transposase K07493 K07493; putative transposase D DFR87_00170 IS256 family transposase K07493 K07493; putative transposase D DFR87_02285 IS256 family transposase K07493 K07493; putative transposase D DFR87_06715 IS256 family transposase K07493 K07493; putative transposase D DFR87_11870 IS256 family transposase K07493 K07493; putative transposase D DFR87_00390 IS256 family transposase K07493 K07493; putative transposase D DFR87_07695 IS256 family transposase K07493 K07493; putative transposase D DFR87_12365 IS256 family transposase K07493 K07493; putative transposase D DFR87_03985 IS256 family transposase K07493 K07493; putative transposase D DFR87_12825 IS256 family transposase K07493 K07493; putative transposase D DFR87_12830 IS256 family transposase K07493 K07493; putative transposase D DFR87_00295 ISH3 family transposase K07495 K07495; putative transposase D DFR87_00415 ISH3 family transposase K07495 K07495; putative transposase D DFR87_01270 ISH3 family transposase K07495 K07495; putative transposase D DFR87_01455 ISH3 family transposase K07495 K07495; putative transposase D DFR87_01750 ISH3 family transposase K07495 K07495; putative transposase D DFR87_01775 ISH3 family transposase K07495 K07495; putative transposase D DFR87_10850 ISH3 family transposase K07495 K07495; putative transposase D DFR87_11580 ISH3 family transposase K07495 K07495; putative transposase D DFR87_13070 ISH3 family transposase K07495 K07495; putative transposase D DFR87_12590 transposase K07495 K07495; putative transposase D DFR87_00120 IS200/IS605 family element transposase accessory protein TnpB K07496 K07496; putative transposase D DFR87_11570 IS200/IS605 family element transposase accessory protein TnpB K07496 K07496; putative transposase D DFR87_03080 IS200/IS605 family element transposase accessory protein TnpB K07496 K07496; putative transposase D DFR87_12650 IS200/IS605 family element transposase accessory protein TnpB K07496 K07496; putative transposase D DFR87_13065 IS200/IS605 family element transposase accessory protein TnpB K07496 K07496; putative transposase D DFR87_11075 IS200/IS605 family element transposase accessory protein TnpB K07496 K07496; putative transposase D DFR87_09245 IS200/IS605 family element transposase accessory protein TnpB K07496 K07496; putative transposase D DFR87_05880 transposase K07496 K07496; putative transposase D DFR87_01745 IS200/IS605 family element transposase accessory protein TnpB K07496 K07496; putative transposase D DFR87_01755 transposase K07496 K07496; putative transposase D DFR87_01015 IS200/IS605 family element transposase accessory protein TnpB K07496 K07496; putative transposase D DFR87_10855 IS200/IS605 family element transposase accessory protein TnpB K07496 K07496; putative transposase D DFR87_00285 IS200/IS605 family element transposase accessory protein TnpB K07496 K07496; putative transposase D DFR87_12375 IS200/IS605 family element transposase accessory protein TnpB K07496 K07496; putative transposase C 99979 Viral proteins C 99998 Others B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D DFR87_04140 amino acid permease K03294 TC.APA; basic amino acid/polyamine antiporter, APA family D DFR87_11235 sodium:solute symporter K03307 TC.SSS; solute:Na+ symporter, SSS family C 99978 Cell growth C 99993 Cell motility C 99995 Signaling proteins D DFR87_04565 ACT domain-containing protein K07166 K07166; ACT domain-containing protein D DFR87_09730 serine/threonine protein kinase K07176 K07176; putative serine/threonine protein kinase D DFR87_10545 DNA-binding protein K06875 PDCD5; programmed cell death protein 5 C 99992 Structural proteins C 99994 Others D DFR87_09955 divalent cation tolerance protein CutA K03926 cutA; periplasmic divalent cation tolerance protein B B 09194 Poorly characterized C 99996 General function prediction only D DFR87_08885 ATPase K06865 K06865; ATPase D DFR87_00280 DEAD/DEAH box helicase K06877 K06877; DEAD/DEAH box helicase domain-containing protein D DFR87_04910 DEAD/DEAH box helicase K06877 K06877; DEAD/DEAH box helicase domain-containing protein D DFR87_08625 metG; methionine--tRNA ligase subunit beta K06878 K06878; tRNA-binding protein D DFR87_02180 MMPL family transporter K06994 K06994; putative drug exporter of the RND superfamily D DFR87_07610 MMPL family transporter K06994 K06994; putative drug exporter of the RND superfamily D DFR87_06545 HAD-IIIA family hydrolase K07025 K07025; putative hydrolase of the HAD superfamily D DFR87_11155 HAD-IA family hydrolase K07025 K07025; putative hydrolase of the HAD superfamily D DFR87_03415 HAD-IA family hydrolase K07025 K07025; putative hydrolase of the HAD superfamily D DFR87_10395 sufB; Fe-S cluster assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB D DFR87_08310 hypothetical protein K07143 K07143; UPF0148 protein D DFR87_11035 DUF202 domain-containing protein K00389 yidH; putative membrane protein D DFR87_10005 DUF373 family protein K08975 K08975; putative membrane protein D DFR87_03145 DUF2070 family protein K08979 K08979; putative membrane protein D DFR87_12605 DUF981 family protein K08980 K08980; putative membrane protein C 99997 Function unknown D DFR87_06850 proteasome assembly chaperone family protein K06869 K06869; uncharacterized protein D DFR87_10375 proteasome assembly chaperone family protein K06869 K06869; uncharacterized protein D DFR87_05245 radical SAM protein K06871 K06871; uncharacterized protein D DFR87_10860 HD domain-containing protein K06885 K06885; uncharacterized protein D DFR87_07835 HD domain-containing protein K06885 K06885; uncharacterized protein D DFR87_09450 HD domain-containing protein K06885 K06885; uncharacterized protein D DFR87_02590 DUF255 domain-containing protein K06888 K06888; uncharacterized protein D DFR87_04170 AAA family ATPase K06921 K06921; uncharacterized protein D DFR87_09185 AAA family ATPase K06921 K06921; uncharacterized protein D DFR87_09285 AAA family ATPase K06921 K06921; uncharacterized protein D DFR87_09330 AAA family ATPase K06921 K06921; uncharacterized protein D DFR87_05200 AAA family ATPase K06921 K06921; uncharacterized protein D DFR87_01130 AAA family ATPase K06921 K06921; uncharacterized protein D DFR87_01630 ATP-binding protein K06921 K06921; uncharacterized protein D DFR87_01840 AAA family ATPase K06921 K06921; uncharacterized protein D DFR87_02535 ATP-binding protein K06921 K06921; uncharacterized protein D DFR87_11740 AAA family ATPase K06921 K06921; uncharacterized protein D DFR87_12440 ATP-binding protein K06921 K06921; uncharacterized protein D DFR87_00735 ATP-binding protein K06921 K06921; uncharacterized protein D DFR87_12610 ATP-binding protein K06921 K06921; uncharacterized protein D DFR87_10930 CoA-binding protein K06929 K06929; uncharacterized protein D DFR87_09990 phosphoesterase K06953 K06953; uncharacterized protein D DFR87_03700 hypothetical protein K07022 K07022; uncharacterized protein D DFR87_12340 transcriptional regulator K07034 K07034; uncharacterized protein D DFR87_06730 beta-CASP ribonuclease aCPSF1 K07041 K07041; uncharacterized protein D DFR87_01365 amidohydrolase family protein K07045 K07045; uncharacterized protein D DFR87_00305 amidohydrolase family protein K07045 K07045; uncharacterized protein D DFR87_01970 amidohydrolase family protein K07045 K07045; uncharacterized protein D DFR87_01305 PIN domain-containing protein K07064 K07064; uncharacterized protein D DFR87_12410 DUF4411 family protein K07064 K07064; uncharacterized protein D DFR87_09200 PIN domain-containing protein K07064 K07064; uncharacterized protein D DFR87_09475 PIN domain-containing protein K07064 K07064; uncharacterized protein D DFR87_01620 PIN domain-containing protein K07064 K07064; uncharacterized protein D DFR87_11050 PIN domain-containing protein K07064 K07064; uncharacterized protein D DFR87_01065 DNA-binding protein K07068 K07068; uncharacterized protein D DFR87_04165 3-hydroxybutyryl-CoA epimerase K07068 K07068; uncharacterized protein D DFR87_04380 DNA-binding protein K07068 K07068; uncharacterized protein D DFR87_05455 DNA-binding protein K07068 K07068; uncharacterized protein D DFR87_05460 DNA-binding protein K07068 K07068; uncharacterized protein D DFR87_10460 DNA-binding protein K07068 K07068; uncharacterized protein D DFR87_12265 hypothetical protein K07068 K07068; uncharacterized protein D DFR87_07665 DNA polymerase subunit beta K07073 K07073; uncharacterized protein D DFR87_01560 TSUP family transporter K07090 K07090; uncharacterized protein D DFR87_08155 TSUP family transporter K07090 K07090; uncharacterized protein D DFR87_04925 TSUP family transporter K07090 K07090; uncharacterized protein D DFR87_10685 peroxiredoxin K07092 K07092; uncharacterized protein D DFR87_10990 sulfur reduction protein DsrE K07092 K07092; uncharacterized protein D DFR87_04230 peroxiredoxin K07092 K07092; uncharacterized protein D DFR87_03565 hypothetical protein K07096 K07096; uncharacterized protein D DFR87_00420 phosphoesterase K07096 K07096; uncharacterized protein D DFR87_00425 hypothetical protein K07096 K07096; uncharacterized protein D DFR87_11100 DHH family phosphoesterase K07097 K07097; uncharacterized protein D DFR87_02630 phosphoribosyltransferase K07101 K07101; uncharacterized protein D DFR87_02915 phosphoribosyltransferase K07101 K07101; uncharacterized protein D DFR87_11840 transcriptional regulator K07108 K07108; uncharacterized protein D DFR87_10075 transcriptional regulator K07108 K07108; uncharacterized protein D DFR87_04240 YeeE/YedE family protein K07112 K07112; uncharacterized protein D DFR87_05665 YeeE/YedE family protein K07112 K07112; uncharacterized protein D DFR87_09770 SDR family NAD(P)-dependent oxidoreductase K07124 K07124; uncharacterized protein D DFR87_07675 radical SAM protein K07129 K07129; uncharacterized protein D DFR87_01160 AAA family ATPase K07133 K07133; uncharacterized protein D DFR87_01325 AAA family ATPase K07133 K07133; uncharacterized protein D DFR87_00710 AAA family ATPase K07133 K07133; uncharacterized protein D DFR87_01615 AAA family ATPase K07133 K07133; uncharacterized protein D DFR87_01965 AAA family ATPase K07133 K07133; uncharacterized protein D DFR87_02110 AAA family ATPase K07133 K07133; uncharacterized protein D DFR87_12585 AAA family ATPase K07133 K07133; uncharacterized protein D DFR87_12925 AAA family ATPase K07133 K07133; uncharacterized protein D DFR87_09190 AAA family ATPase K07133 K07133; uncharacterized protein D DFR87_00250 AAA family ATPase K07133 K07133; uncharacterized protein D DFR87_07040 FAD-dependent oxidoreductase K07137 K07137; uncharacterized protein D DFR87_07325 PIN domain-containing protein K07158 K07158; uncharacterized protein D DFR87_11110 DUF763 domain-containing protein K09003 K09003; uncharacterized protein D DFR87_06980 DUF99 family protein K09120 K09120; uncharacterized protein D DFR87_08510 adenosine monophosphate-protein transferase K09129 K09129; uncharacterized protein D DFR87_06040 amrA; AmmeMemoRadiSam system protein A K09141 K09141; uncharacterized protein D DFR87_11510 DUF429 domain-containing protein K09147 K09147; uncharacterized protein D DFR87_03035 DUF424 family protein K09148 K09148; uncharacterized protein D DFR87_05640 DUF460 domain-containing protein K09150 K09150; uncharacterized protein D DFR87_10525 DUF711 family protein K09157 K09157; uncharacterized protein D DFR87_04560 DUF711 family protein K09157 K09157; uncharacterized protein D DFR87_01220 DUF2075 domain-containing protein K09384 K09384; uncharacterized protein D DFR87_02955 carbon monoxide dehydrogenase K09386 K09386; uncharacterized protein D DFR87_06300 hypothetical protein K09717 K09717; uncharacterized protein D DFR87_08315 hypothetical protein K09721 K09721; uncharacterized protein D DFR87_08820 hypothetical protein K09732 K09732; uncharacterized protein D DFR87_09710 hypothetical protein K09736 K09736; uncharacterized protein D DFR87_10040 DUF61 family protein K09737 K09737; uncharacterized protein D DFR87_03480 DUF371 domain-containing protein K09738 K09738; uncharacterized protein D DFR87_03690 DUF790 family protein K09744 K09744; uncharacterized protein D DFR87_08505 DUF309 domain-containing protein K09763 K09763; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: June 20, 2024