+D GENES KO
#
KEGG Orthology (KO) - Methanomethylovorans hollandica
%
!
A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:mhz00010]
D Metho_2066 thermophilic glucose-6-phosphate isomerase-like enzyme K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]
D Metho_0565 hexose kinase, 1-phosphofructokinase family K16370 pfkB; 6-phosphofructokinase 2 [EC:2.7.1.11]
D Metho_2034 archaeal ADP-dependent phosphofructokinase/glucokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
D Metho_2035 ADP-specific phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
D Metho_0581 fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D Metho_0427 DhnA-type fructose-1,6-bisphosphate aldolase-like enzyme K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D Metho_0254 putative phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Metho_0268 putative phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Metho_0262 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D Metho_0889 glyceraldehyde-3-phosphate dehydrogenase, type II K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D Metho_0588 3-phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D Metho_0146 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Metho_1170 phosphoglyceromutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Metho_2081 putative homoserine kinase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Metho_0369 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Metho_1947 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D Metho_1630 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D Metho_1310 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D Metho_0756 phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D Metho_2440 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Metho_2441 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D Metho_2438 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D Metho_2439 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D Metho_0723 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Metho_0722 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Metho_0357 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Metho_1338 DNA-binding protein, excisionase family K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2047 acyl-CoA synthetase/AMP-acid ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2385 acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_0585 ADP-forming acetyl coenzyme A synthetase K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D Metho_2209 phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
C 00020 Citrate cycle (TCA cycle) [PATH:mhz00020]
D Metho_1112 citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D Metho_1936 isopropylmalate/homocitrate/citramalate synthase K05942 E2.3.3.3; citrate (Re)-synthase [EC:2.3.3.3]
D Metho_1110 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D Metho_1937 isocitrate/isopropylmalate dehydrogenase K00030 IDH3; isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]
D Metho_0723 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Metho_0722 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Metho_1750 hydro-lyase, Fe-S type, tartrate/fumarate subfamily K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D Metho_1749 hydro-lyase family enzyme, Fe-S type, tartrate/fumarate subfamily K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D Metho_2062 malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Metho_0790 acetyl-CoA carboxylase, biotin carboxylase subunit K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]
D Metho_0789 oxaloacetate decarboxylase alpha subunit K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]
D Metho_2440 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Metho_2441 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D Metho_2438 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D Metho_2439 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00030 Pentose phosphate pathway [PATH:mhz00030]
D Metho_2066 thermophilic glucose-6-phosphate isomerase-like enzyme K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]
D Metho_1012 ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D Metho_0261 formaldehyde-activating enzyme K13812 fae-hps; bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43]
D Metho_0199 6-phospho 3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D Metho_0283 Demethylmenaquinone methyltransferase K13831 hps-phi; 3-hexulose-6-phosphate synthase / 6-phospho-3-hexuloisomerase [EC:4.1.2.43 5.3.1.27]
D Metho_2209 phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Metho_2361 ribose-1,5-bisphosphate isomerase, e2b2 family K18237 K18237; ribose 1,5-bisphosphate isomerase [EC:5.3.1.29]
D Metho_0188 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D Metho_0168 aldehyde:ferredoxin oxidoreductase K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]
D Metho_1939 putative glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D Metho_0427 DhnA-type fructose-1,6-bisphosphate aldolase-like enzyme K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D Metho_0254 putative phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Metho_0268 putative phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Metho_0581 fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D Metho_0565 hexose kinase, 1-phosphofructokinase family K16370 pfkB; 6-phosphofructokinase 2 [EC:2.7.1.11]
D Metho_2034 archaeal ADP-dependent phosphofructokinase/glucokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
D Metho_2035 ADP-specific phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
C 00040 Pentose and glucuronate interconversions [PATH:mhz00040]
D Metho_2336 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D Metho_0488 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D Metho_0443 ribulose-5-phosphate 4-epimerase-like epimerase or aldolase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]
C 00051 Fructose and mannose metabolism [PATH:mhz00051]
D Metho_2261 sugar kinase, ribokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D Metho_0489 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
D Metho_2209 phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Metho_0667 Nucleoside-diphosphate-sugar pyrophosphorylase family protein K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D Metho_1978 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]
D Metho_0443 ribulose-5-phosphate 4-epimerase-like epimerase or aldolase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]
D Metho_0565 hexose kinase, 1-phosphofructokinase family K16370 pfkB; 6-phosphofructokinase 2 [EC:2.7.1.11]
D Metho_0581 fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D Metho_0427 DhnA-type fructose-1,6-bisphosphate aldolase-like enzyme K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D Metho_0254 putative phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Metho_0268 putative phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Metho_0262 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 00052 Galactose metabolism [PATH:mhz00052]
D Metho_1097 galactose-1-phosphate uridylyltransferase K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
D Metho_1795 nucleoside-diphosphate-sugar epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Metho_1482 nucleoside-diphosphate-sugar epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Metho_1724 nucleoside-diphosphate-sugar epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Metho_0488 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D Metho_2209 phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Metho_0565 hexose kinase, 1-phosphofructokinase family K16370 pfkB; 6-phosphofructokinase 2 [EC:2.7.1.11]
C 00053 Ascorbate and aldarate metabolism [PATH:mhz00053]
D Metho_2336 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D Metho_0357 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00500 Starch and sucrose metabolism [PATH:mhz00500]
D Metho_0488 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D Metho_1107 alpha-glucan phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
D Metho_1364 glycosidase K01176 AMY; alpha-amylase [EC:3.2.1.1]
D Metho_1095 alpha-amylase/alpha-mannosidase K01176 AMY; alpha-amylase [EC:3.2.1.1]
D Metho_1094 alpha-amylase/alpha-mannosidase K07405 E3.2.1.1A; alpha-amylase [EC:3.2.1.1]
D Metho_1483 glycosyltransferase K16148 glgM; alpha-maltose-1-phosphate synthase [EC:2.4.1.342]
D Metho_2209 phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Metho_2066 thermophilic glucose-6-phosphate isomerase-like enzyme K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]
D Metho_2261 sugar kinase, ribokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:mhz00520]
D Metho_2261 sugar kinase, ribokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D Metho_1849 glucosamine--fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D Metho_1848 phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D Metho_1847 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D Metho_1979 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D Metho_1474 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D Metho_1796 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
D Metho_1732 UDP-N-acetylglucosamine 2-epimerase K13019 wbpI; UDP-GlcNAc3NAcA epimerase [EC:5.1.3.23]
D Metho_2209 phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Metho_0488 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D Metho_2336 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D Metho_1097 galactose-1-phosphate uridylyltransferase K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
D Metho_1795 nucleoside-diphosphate-sugar epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Metho_1482 nucleoside-diphosphate-sugar epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Metho_1724 nucleoside-diphosphate-sugar epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Metho_2066 thermophilic glucose-6-phosphate isomerase-like enzyme K06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]
D Metho_0667 Nucleoside-diphosphate-sugar pyrophosphorylase family protein K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D Metho_0489 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
D Metho_1978 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]
C 00620 Pyruvate metabolism [PATH:mhz00620]
D Metho_1338 DNA-binding protein, excisionase family K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2047 acyl-CoA synthetase/AMP-acid ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2385 acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2440 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Metho_2441 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D Metho_2438 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D Metho_2439 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D Metho_0723 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Metho_0722 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Metho_1947 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D Metho_0495 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D Metho_0357 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Metho_0585 ADP-forming acetyl coenzyme A synthetase K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D Metho_2134 Zn-dependent hydrolase, glyoxylase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D Metho_2404 Zn-dependent hydrolase, glyoxylase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D Metho_1305 hypothetical protein K22373 larA; lactate racemase [EC:5.1.2.1]
D Metho_0790 acetyl-CoA carboxylase, biotin carboxylase subunit K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]
D Metho_0789 oxaloacetate decarboxylase alpha subunit K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]
D Metho_2062 malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Metho_1750 hydro-lyase, Fe-S type, tartrate/fumarate subfamily K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D Metho_1749 hydro-lyase family enzyme, Fe-S type, tartrate/fumarate subfamily K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D Metho_1630 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D Metho_1310 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D Metho_0756 phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D Metho_2374 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Metho_2402 isopropylmalate/citramalate/homocitrate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D Metho_0886 isopropylmalate/homocitrate/citramalate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:mhz00630]
D Metho_1338 DNA-binding protein, excisionase family K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2047 acyl-CoA synthetase/AMP-acid ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2385 acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2062 malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Metho_1112 citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D Metho_1110 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D Metho_2374 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Metho_2409 FAD/FMN-dependent dehydrogenase K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14]
D Metho_1739 catalase K03781 katE; catalase [EC:1.11.1.6]
D Metho_2284 sucrose-phosphate phosphatase-like hydrolase, Archaeal K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18]
D Metho_1955 ribulose 1,5-bisphosphate carboxylase, large subunit K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D Metho_1660 ribulose 1,5-bisphosphate carboxylase, large subunit K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D Metho_0301 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Metho_0307 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Metho_2321 glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Metho_1939 putative glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D Metho_0132 isocitrate/isopropylmalate dehydrogenase K07246 ttuC; tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase [EC:1.1.1.93 4.1.1.73 1.1.1.83]
C 00640 Propanoate metabolism [PATH:mhz00640]
D Metho_1338 DNA-binding protein, excisionase family K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2047 acyl-CoA synthetase/AMP-acid ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2385 acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_0585 ADP-forming acetyl coenzyme A synthetase K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D Metho_2440 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Metho_2441 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D Metho_2438 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D Metho_2439 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00650 Butanoate metabolism [PATH:mhz00650]
D Metho_2374 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Metho_0132 isocitrate/isopropylmalate dehydrogenase K07246 ttuC; tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase [EC:1.1.1.93 4.1.1.73 1.1.1.83]
D Metho_2357 NAD-dependent aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D Metho_2440 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Metho_2441 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D Metho_2438 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D Metho_2439 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D Metho_0723 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Metho_0722 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Metho_2375 hydroxymethylglutaryl-CoA synthase, putative K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D Metho_2355 thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Metho_1791 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Metho_1790 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D Metho_1302 alpha-acetolactate decarboxylase K01575 alsD; acetolactate decarboxylase [EC:4.1.1.5]
C 00660 C5-Branched dibasic acid metabolism [PATH:mhz00660]
D Metho_2355 thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Metho_1791 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Metho_1790 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D Metho_1302 alpha-acetolactate decarboxylase K01575 alsD; acetolactate decarboxylase [EC:4.1.1.5]
D Metho_1792 isopropylmalate/citramalate/homocitrate synthase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]
D Metho_0194 homoaconitate hydratase family protein/3-isopropylmalate dehydratase, large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D Metho_0133 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
C 00562 Inositol phosphate metabolism [PATH:mhz00562]
D Metho_0888 inositol monophosphatase/fructose-1,6-bisphosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D Metho_2257 myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D Metho_0262 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:mhz00190]
D Metho_0518 Cbb3-type cytochrome oxidase, subunit 1 K15862 ccoNO; cytochrome c oxidase cbb3-type subunit I/II [EC:7.1.1.9]
D Metho_0839 ATP synthase, A subunit K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
D Metho_0840 ATP synthase, B subunit K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B
D Metho_0837 ATP synthase A1, C subunit K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C
D Metho_0841 H(+)-transporting ATP synthase, vacuolar type, subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D
D Metho_0836 archaeal/vacuolar-type H+-ATPase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E
D Metho_0838 archaeal/vacuolar-type H+-ATPase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F
D Metho_0833 ATP synthase, H subunit K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H
D Metho_0834 archaeal/vacuolar-type H+-ATPase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I
D Metho_0835 ATP synthase subunit C K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K
D Metho_0371 inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
D Metho_0782 polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:mhz00710]
D Metho_1955 ribulose 1,5-bisphosphate carboxylase, large subunit K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D Metho_1660 ribulose 1,5-bisphosphate carboxylase, large subunit K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D Metho_0588 3-phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D Metho_0889 glyceraldehyde-3-phosphate dehydrogenase, type II K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D Metho_0581 fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D Metho_1012 ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D Metho_0262 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D Metho_1630 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D Metho_2062 malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00720 Other carbon fixation pathways [PATH:mhz00720]
D Metho_2440 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Metho_2441 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D Metho_2438 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D Metho_2439 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D Metho_1310 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D Metho_0756 phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D Metho_1630 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D Metho_0790 acetyl-CoA carboxylase, biotin carboxylase subunit K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]
D Metho_0789 oxaloacetate decarboxylase alpha subunit K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]
D Metho_2062 malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Metho_1750 hydro-lyase, Fe-S type, tartrate/fumarate subfamily K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]
D Metho_1749 hydro-lyase family enzyme, Fe-S type, tartrate/fumarate subfamily K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]
D Metho_2408 Fe-S oxidoreductase K18210 tfrB; fumarate reductase (CoM/CoB) subunit B [EC:1.3.4.1]
D Metho_2374 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Metho_0723 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Metho_0722 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Metho_1110 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D Metho_2320 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D Metho_2393 5,10-methylenetetrahydrofolate reductase K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
D Metho_1412 carbon-monoxide dehydrogenase, catalytic subunit K00198 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4]
D Metho_0980 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245]
D Metho_0979 CO dehydrogenase/acetyl-CoA synthase, delta subunit K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245]
D Metho_1338 DNA-binding protein, excisionase family K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2047 acyl-CoA synthetase/AMP-acid ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2385 acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 00680 Methane metabolism [PATH:mhz00680]
D Metho_0975 CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit K00192 cdhA; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit alpha [EC:1.2.7.4]
D Metho_0976 CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit K00195 cdhB; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit epsilon
D Metho_0977 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex, beta subunit K00193 cdhC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit beta [EC:2.3.1.169]
D Metho_0980 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245]
D Metho_0979 CO dehydrogenase/acetyl-CoA synthase, delta subunit K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245]
D Metho_1412 carbon-monoxide dehydrogenase, catalytic subunit K00198 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4]
D Metho_2321 glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Metho_1939 putative glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D Metho_0369 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Metho_2062 malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Metho_0427 DhnA-type fructose-1,6-bisphosphate aldolase-like enzyme K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D Metho_0254 putative phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Metho_0268 putative phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Metho_0581 fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D Metho_0565 hexose kinase, 1-phosphofructokinase family K16370 pfkB; 6-phosphofructokinase 2 [EC:2.7.1.11]
D Metho_2034 archaeal ADP-dependent phosphofructokinase/glucokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
D Metho_2035 ADP-specific phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
D Metho_0199 6-phospho 3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D Metho_0261 formaldehyde-activating enzyme K13812 fae-hps; bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43]
D Metho_0283 Demethylmenaquinone methyltransferase K13831 hps-phi; 3-hexulose-6-phosphate synthase / 6-phospho-3-hexuloisomerase [EC:4.1.2.43 5.3.1.27]
D Metho_0729 formylmethanofuran dehydrogenase subunit A K00200 fwdA; formylmethanofuran dehydrogenase subunit A [EC:1.2.7.12]
D Metho_0732 formylmethanofuran dehydrogenase subunit B K00201 fwdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.7.12]
D Metho_1809 formylmethanofuran dehydrogenase subunit B K00201 fwdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.7.12]
D Metho_0730 formylmethanofuran dehydrogenase subunit C K00202 fwdC; formylmethanofuran dehydrogenase subunit C [EC:1.2.7.12]
D Metho_0731 formylmethanofuran dehydrogenase subunit D K00203 fwdD; formylmethanofuran dehydrogenase subunit D [EC:1.2.7.12]
D Metho_1808 formylmethanofuran dehydrogenase subunit D K00203 fwdD; formylmethanofuran dehydrogenase subunit D [EC:1.2.7.12]
D Metho_0728 NADH:ubiquinone oxidoreductase chain I-like protein K00205 fwdF; 4Fe-4S ferredoxin
D Metho_1080 NADH:ubiquinone oxidoreductase chain I-like protein K00205 fwdF; 4Fe-4S ferredoxin
D Metho_1810 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) K11260 fwdG; 4Fe-4S ferredoxin
D Metho_1571 formylmethanofuran dehydrogenase subunit E K11261 fwdE; formylmethanofuran dehydrogenase subunit E [EC:1.2.7.12]
D Metho_2457 formylmethanofuran--tetrahydromethanopterin N-formyltransferase K00672 ftr; formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101]
D Metho_1529 methenyltetrahydromethanopterin cyclohydrolase K01499 mch; methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27]
D Metho_0243 coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin dehydrogenase K00319 mtd; methylenetetrahydromethanopterin dehydrogenase [EC:1.5.98.1]
D Metho_0305 coenzyme F420-reducing hydrogenase, beta subunit K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1]
D Metho_1361 coenzyme F420-reducing hydrogenase, beta subunit K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1]
D Metho_1162 formaldehyde-activating enzyme K10713 fae; 5,6,7,8-tetrahydromethanopterin hydro-lyase [EC:4.2.1.147]
D Metho_2247 5,10-methylenetetrahydromethanopterin reductase K00320 mer; 5,10-methylenetetrahydromethanopterin reductase [EC:1.5.98.2]
D Metho_2092 N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit A K00577 mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:7.2.1.4]
D Metho_0912 tetrahydromethanopterin S-methyltransferase, subunit A K00577 mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:7.2.1.4]
D Metho_2093 tetrahydromethanopterin S-methyltransferase, subunit B K00578 mtrB; tetrahydromethanopterin S-methyltransferase subunit B [EC:7.2.1.4]
D Metho_2094 N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit C K00579 mtrC; tetrahydromethanopterin S-methyltransferase subunit C [EC:7.2.1.4]
D Metho_2095 N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit D K00580 mtrD; tetrahydromethanopterin S-methyltransferase subunit D [EC:7.2.1.4]
D Metho_2096 N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit E K00581 mtrE; tetrahydromethanopterin S-methyltransferase subunit E [EC:7.2.1.4]
D Metho_2091 tetrahydromethanopterin S-methyltransferase, F subunit K00582 mtrF; tetrahydromethanopterin S-methyltransferase subunit F [EC:7.2.1.4]
D Metho_2090 N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit G K00583 mtrG; tetrahydromethanopterin S-methyltransferase subunit G [EC:7.2.1.4]
D Metho_2089 N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H K00584 mtrH; tetrahydromethanopterin S-methyltransferase subunit H [EC:7.2.1.4]
D Metho_1670 methyl-coenzyme M reductase, alpha subunit K00399 mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
D Metho_0164 methyl coenzyme M reductase system, component A2 K00400 K00400; methyl coenzyme M reductase system, component A2
D Metho_0328 ATPase component of various ABC-type transport systems with duplicated ATPase domain K00400 K00400; methyl coenzyme M reductase system, component A2
D Metho_1666 methyl-coenzyme M reductase, beta subunit K00401 mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
D Metho_1669 methyl-coenzyme M reductase, gamma subunit K00402 mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
D Metho_1668 methyl-coenzyme M reductase I operon protein C K03421 mcrC; methyl-coenzyme M reductase subunit C
D Metho_1667 methyl-coenzyme M reductase operon protein D K03422 mcrD; methyl-coenzyme M reductase subunit D
D Metho_1079 polyferredoxin, heterodixulfide reductase subunit A K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D Metho_0299 CoB--CoM heterodisulfide reductase, subunit B K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D Metho_0300 CoB--CoM heterodisulfide reductase, subunit C K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D Metho_1506 Fe-S oxidoreductase K08264 hdrD; heterodisulfide reductase subunit D [EC:1.8.98.1]
D Metho_1043 Fe-S oxidoreductase K08264 hdrD; heterodisulfide reductase subunit D [EC:1.8.98.1]
D Metho_1505 nitrate reductase gamma subunit K08265 hdrE; heterodisulfide reductase subunit E [EC:1.8.98.1]
D Metho_1338 DNA-binding protein, excisionase family K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2047 acyl-CoA synthetase/AMP-acid ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2385 acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2440 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Metho_2441 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D Metho_2438 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D Metho_2439 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D Metho_1310 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D Metho_0756 phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D Metho_0146 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Metho_1170 phosphoglyceromutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Metho_2081 putative homoserine kinase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Metho_1646 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D Metho_0242 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D Metho_0761 methyltransferase, MtaA/CmuA family K14080 mtaA; [methyl-Co(III) methanol/glycine betaine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.246 2.1.1.377]
D Metho_0776 methyltransferase, MtaA/CmuA family K14080 mtaA; [methyl-Co(III) methanol/glycine betaine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.246 2.1.1.377]
D Metho_1260 methyltransferase, MtaA/CmuA family K14080 mtaA; [methyl-Co(III) methanol/glycine betaine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.246 2.1.1.377]
D Metho_0775 Methanol-cobalamin methyltransferase B subunit K04480 mtaB; methanol---5-hydroxybenzimidazolylcobamide Co-methyltransferase [EC:2.1.1.90]
D Metho_1601 Methanol-cobalamin methyltransferase B subunit K04480 mtaB; methanol---5-hydroxybenzimidazolylcobamide Co-methyltransferase [EC:2.1.1.90]
D Metho_0774 methyltransferase cognate corrinoid protein K14081 mtaC; methanol corrinoid protein
D Metho_1599 methyltransferase cognate corrinoid protein K14081 mtaC; methanol corrinoid protein
D Metho_1600 methyltransferase cognate corrinoid protein K14081 mtaC; methanol corrinoid protein
D Metho_0007 methyltransferase, MtaA/CmuA family K14082 mtbA; [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.247]
D Metho_0037 methyltransferase, MtaA/CmuA family K14082 mtbA; [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.247]
D Metho_0355 methyltransferase, MtaA/CmuA family K14082 mtbA; [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.247]
D Metho_0027 trimethylamine:corrinoid methyltransferase K14083 mttB; trimethylamine---corrinoid protein Co-methyltransferase [EC:2.1.1.250]
D Metho_0028 methyltransferase cognate corrinoid protein K14084 mttC; trimethylamine corrinoid protein
D Metho_0131 putative cobalamin binding protein K14084 mttC; trimethylamine corrinoid protein
D Metho_1575 putative cobalamin binding protein K14084 mttC; trimethylamine corrinoid protein
D Metho_0607 putative cobalamin binding protein K14084 mttC; trimethylamine corrinoid protein
D Metho_0036 Monomethylamine methyltransferase MtmB K16176 mtmB; methylamine---corrinoid protein Co-methyltransferase [EC:2.1.1.248]
D Metho_0013 Monomethylamine methyltransferase MtmB K16176 mtmB; methylamine---corrinoid protein Co-methyltransferase [EC:2.1.1.248]
D Metho_0035 Monomethylamine methyltransferase MtmB K16176 mtmB; methylamine---corrinoid protein Co-methyltransferase [EC:2.1.1.248]
D Metho_0014 methyltransferase cognate corrinoid protein K16177 mtmC; monomethylamine corrinoid protein
D Metho_0034 methyltransferase cognate corrinoid protein K16177 mtmC; monomethylamine corrinoid protein
D Metho_0033 dimethylamine:corrinoid methyltransferase K16178 mtbB; dimethylamine---corrinoid protein Co-methyltransferase [EC:2.1.1.249]
D Metho_1026 dimethylamine:corrinoid methyltransferase K16178 mtbB; dimethylamine---corrinoid protein Co-methyltransferase [EC:2.1.1.249]
D Metho_0032 methyltransferase cognate corrinoid protein K16179 mtbC; dimethylamine corrinoid protein
D Metho_1027 methyltransferase cognate corrinoid protein K16179 mtbC; dimethylamine corrinoid protein
D Metho_1758 sulfopyruvate decarboxylase, alpha subunit K06034 comD; sulfopyruvate decarboxylase subunit alpha [EC:4.1.1.79]
D Metho_1757 sulfopyruvate decarboxylase, beta subunit K13039 comE; sulfopyruvate decarboxylase subunit beta [EC:4.1.1.79]
D Metho_0950 radical SAM domain protein, CofH subfamily K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147]
D Metho_0951 radical SAM domain protein, CofH subfamily K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147]
D Metho_0952 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit K11780 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [EC:4.3.1.32]
D Metho_0949 2-phospho-L-lactate guanylyltransferase K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105]
D Metho_2233 LPPG:FO 2-phospho-L-lactate transferase K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28]
D Metho_2079 F420-0:gamma-glutamyl ligase K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
D Metho_0886 isopropylmalate/homocitrate/citramalate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
D Metho_0694 homoaconitate hydratase family protein/3-isopropylmalate dehydratase, large subunit K16792 aksD; methanogen homoaconitase large subunit [EC:4.2.1.114]
D Metho_0481 3-isopropylmalate dehydratase, small subunit K16793 aksE; methanogen homoaconitase small subunit [EC:4.2.1.114]
D Metho_0479 isopropylmalate/isohomocitrate dehydrogenase K10978 aksF; methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
D Metho_2460 tyrosine decarboxylase MnfA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D Metho_0940 putative ATP-utilizing enzyme (ATP-grasp superfamily) K06914 mfnD; tyramine---L-glutamate ligase [EC:6.3.4.24]
D Metho_1723 hypothetical protein K09733 mfnB; (5-formylfuran-3-yl)methyl phosphate synthase [EC:4.2.3.153]
D Metho_0766 aspartate/tyrosine/aromatic aminotransferase K19793 mfnC; (5-formylfuran-3-yl)methyl phosphate transaminase [EC:2.6.1.108]
D Metho_0938 putative kinase, aspartokinase/uridylate kinase K07144 mfnE; 5-(aminomethyl)-3-furanmethanol phosphate kinase [EC:2.7.4.31]
D Metho_0939 putative H4MPT-linked C1 transfer pathway protein K07072 mfnF; (4-(4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl)furan-2-yl)methanamine synthase [EC:2.5.1.131]
C 00910 Nitrogen metabolism [PATH:mhz00910]
D Metho_1073 hydroxylamine reductase K05601 hcp; hydroxylamine reductase [EC:1.7.99.1]
D Metho_0402 hydroxylamine reductase K05601 hcp; hydroxylamine reductase [EC:1.7.99.1]
D Metho_0754 glutamate dehydrogenase/leucine dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D Metho_0301 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Metho_0307 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Metho_0491 NADPH-dependent glutamate synthase, homotetrameric K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]
C 00920 Sulfur metabolism [PATH:mhz00920]
D Metho_2116 ABC transporter, substrate-binding protein, aliphatic sulfonates family K15553 ssuA; sulfonate transport system substrate-binding protein
D Metho_2117 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component K15554 ssuC; sulfonate transport system permease protein
D Metho_2118 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D Metho_0142 PAPS reductase/FAD synthetase family protein K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D Metho_0492 PAPS reductase/FAD synthetase family protein K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D Metho_0335 dissimilatory sulfite reductase (desulfoviridin), alpha/beta subunit K00385 asrC; anaerobic sulfite reductase subunit C
D Metho_0595 serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D Metho_1735 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D Metho_0596 cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47]
D Metho_1089 homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D Metho_0527 putative protein-S-isoprenylcysteine methyltransferase K21310 mddA; methanethiol S-methyltransferase [EC:2.1.1.334]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:mhz00061]
D Metho_2449 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:mhz00071]
D Metho_2374 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Metho_0357 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:mhz00561]
D Metho_1939 putative glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D Metho_0357 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00564 Glycerophospholipid metabolism [PATH:mhz00564]
D Metho_0454 phosphatidylserine decarboxylase precursor-related protein K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]
D Metho_0547 glycerol dehydrogenase-like oxidoreductase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
D Metho_0329 phosphoglycerol geranylgeranyltransferase K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
D Metho_1408 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42]
D Metho_0338 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42]
D Metho_1973 CDP-diglyceride synthetase K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67]
D Metho_0453 CDP-diacylglycerol--serine O-phosphatidyltransferase K19665 pssA; archaetidylserine synthase [EC:2.7.8.38]
D Metho_0947 geranylgeranyl reductase family protein K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
D Metho_0239 flavin-dependent dehydrogenase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
D Metho_1933 geranylgeranyl reductase family protein K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
D Metho_1579 geranylgeranyl reductase family protein K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:mhz00230]
D Metho_2209 phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Metho_0188 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D Metho_0711 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D Metho_1971 phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D Metho_2322 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D Metho_2278 phosphoribosylformylglycinamidine synthase II K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D Metho_1050 phosphoribosylformylglycinamidine synthase, purS protein K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D Metho_1051 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D Metho_2084 phosphoribosylaminoimidazole synthetase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D Metho_0725 phosphoribosylcarboxyaminoimidazole (NCAIR) mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D Metho_2268 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D Metho_1951 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D Metho_0143 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D Metho_0136 ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligase) K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23]
D Metho_0550 ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligase) K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23]
D Metho_2234 PRPP-binding protein, adenine/guanine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D Metho_0467 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D Metho_1694 sugar kinase, ribokinase K22026 K22026; nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-]
D Metho_1518 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D Metho_0571 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D Metho_0287 GMP synthase, glutamine-hydrolyzing, C-terminal domain or B subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Metho_0270 GMP synthase, glutamine-hydrolyzing, N-terminal domain or A subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Metho_1134 cytosine/adenosine deaminase K01487 guaD; guanine deaminase [EC:3.5.4.3]
D Metho_2110 anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D Metho_2481 anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D Metho_2654 oxygen-sensitive ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D Metho_0781 exopolyphosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
D Metho_2372 adenylyl cyclase CyaB, putative K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]
D Metho_0852 adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D Metho_1154 AMP phosphorylase K18931 deoA; AMP phosphorylase [EC:2.4.2.57]
D Metho_1527 adenine deaminase K01486 ade; adenine deaminase [EC:3.5.4.2]
D Metho_2001 adenylate kinase family protein K00939 adk; adenylate kinase [EC:2.7.4.3]
D Metho_2181 putative nucleoside kinase, CMP and AMP kinase K18532 AK6; adenylate kinase [EC:2.7.4.3]
C 00240 Pyrimidine metabolism [PATH:mhz00240]
D Metho_1084 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D Metho_1083 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D Metho_0282 aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D Metho_0281 aspartate carbamoyltransferase, regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D Metho_0226 dihydroorotase, multifunctional complex type K01465 URA4; dihydroorotase [EC:3.5.2.3]
D Metho_0820 dihydroorotate dehydrogenase family protein K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14]
D Metho_0819 2-polyprenylphenol hydroxylase-like oxidoreductase K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit
D Metho_1972 orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D Metho_0780 orotidine 5''-phosphate decarboxylase, subfamily 1 K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D Metho_0126 uridylate kinase, putative K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D Metho_1518 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D Metho_0933 MAF protein K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]
D Metho_1424 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D Metho_1999 cytidylate kinase, putative K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D Metho_0467 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D Metho_1694 sugar kinase, ribokinase K22026 K22026; nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-]
D Metho_1154 AMP phosphorylase K18931 deoA; AMP phosphorylase [EC:2.4.2.57]
D Metho_1301 cytosine/adenosine deaminase K03365 FCY1; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21]
D Metho_2110 anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D Metho_2481 anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D Metho_2654 oxygen-sensitive ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D Metho_2078 deoxycytidylate deaminase K01493 comEB; dCMP deaminase [EC:3.5.4.12]
D Metho_1720 thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D Metho_0255 deoxycytidine deaminase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Metho_0661 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:mhz00250]
D Metho_0198 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_0923 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_1085 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D Metho_1009 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D Metho_0852 adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D Metho_1951 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D Metho_0282 aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D Metho_0281 aspartate carbamoyltransferase, regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D Metho_2357 NAD-dependent aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D Metho_0491 NADPH-dependent glutamate synthase, homotetrameric K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]
D Metho_0754 glutamate dehydrogenase/leucine dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D Metho_0301 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Metho_0307 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Metho_1084 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D Metho_1083 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D Metho_1051 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D Metho_1849 glucosamine--fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D Metho_0711 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:mhz00260]
D Metho_2083 aspartate kinase, monofunctional class K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Metho_0124 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D Metho_1680 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D Metho_0651 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D Metho_2321 glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Metho_1939 putative glycerate kinase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D Metho_0146 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Metho_1170 phosphoglyceromutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Metho_2081 putative homoserine kinase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Metho_1646 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D Metho_0242 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D Metho_0862 tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D Metho_0863 tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D Metho_1857 pyridoxal-phosphate dependent TrpB-like enzyme K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
C 00270 Cysteine and methionine metabolism [PATH:mhz00270]
D Metho_0595 serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D Metho_1735 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D Metho_0596 cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47]
D Metho_2427 methionine synthase II (cobalamin-independent) K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D Metho_0094 archaeal S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D Metho_1914 cytosine deaminase-like metal-dependent hydrolase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D Metho_1549 purine nucleoside phosphorylase K19696 mtiP; 5'-methylthioinosine phosphorylase [EC:2.4.2.44]
D Metho_2104 S-methyl-5-thioribose-1-phosphate isomerase K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23]
D Metho_2701 DNA-methyltransferase Dcm K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D Metho_2718 site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D Metho_1915 adenosylhomocysteinase K01566 E3.13.1.9; S-inosyl-L-homocysteine hydrolase [EC:3.13.1.9]
D Metho_2083 aspartate kinase, monofunctional class K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Metho_0124 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D Metho_1680 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D Metho_0925 hypothetical protein K23975 E2.8.1.16; L-aspartate semialdehyde sulfurtransferase [EC:2.8.1.16]
D Metho_0926 NADH:ubiquinone oxidoreductase chain I-like protein K23976 K23976; L-aspartate semialdehyde sulfurtransferase ferredoxin
D Metho_1089 homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D Metho_0599 OAH/OAS sulfhydrylase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D Metho_1088 OAH/OAS sulfhydrylase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D Metho_2300 branched-chain amino acid aminotransferase, group I K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Metho_0198 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_0923 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_2062 malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Metho_1646 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
C 00280 Valine, leucine and isoleucine degradation [PATH:mhz00280]
D Metho_2300 branched-chain amino acid aminotransferase, group I K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Metho_2049 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00186 vorA; 2-oxoisovalerate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.7]
D Metho_2050 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00187 vorB; 2-oxoisovalerate ferredoxin oxidoreductase beta subunit [EC:1.2.7.7]
D Metho_2048 ferredoxin K00188 vorD; 2-oxoisovalerate ferredoxin oxidoreductase delta subunit [EC:1.2.7.7]
D Metho_0357 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Metho_2374 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Metho_2375 hydroxymethylglutaryl-CoA synthase, putative K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:mhz00290]
D Metho_1792 isopropylmalate/citramalate/homocitrate synthase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]
D Metho_0194 homoaconitate hydratase family protein/3-isopropylmalate dehydratase, large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D Metho_0133 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D Metho_2355 thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Metho_1791 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Metho_1790 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D Metho_1789 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D Metho_0664 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D Metho_2300 branched-chain amino acid aminotransferase, group I K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Metho_2402 isopropylmalate/citramalate/homocitrate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00300 Lysine biosynthesis [PATH:mhz00300]
D Metho_1680 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D Metho_2083 aspartate kinase, monofunctional class K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Metho_0124 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D Metho_0279 dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D Metho_0280 dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D Metho_0450 acetylornithine/succinylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D Metho_1006 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]
D Metho_0844 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D Metho_0886 isopropylmalate/homocitrate/citramalate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
D Metho_0694 homoaconitate hydratase family protein/3-isopropylmalate dehydratase, large subunit K16792 aksD; methanogen homoaconitase large subunit [EC:4.2.1.114]
D Metho_0481 3-isopropylmalate dehydratase, small subunit K16793 aksE; methanogen homoaconitase small subunit [EC:4.2.1.114]
D Metho_0479 isopropylmalate/isohomocitrate dehydrogenase K10978 aksF; methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
D Metho_0021 pyrrolysine biosynthesis radical SAM protein K16180 pylB; methylornithine synthase [EC:5.4.99.58]
D Metho_0020 pyrrolysine biosynthesis protein PylC K16181 pylC; 3-methylornithine--L-lysine ligase [EC:6.3.2.59]
D Metho_0019 pyrrolysine biosynthesis protein PylD K16182 pylD; 3-methylornithyl-N6-L-lysine dehydrogenase [EC:1.4.1.-]
C 00310 Lysine degradation [PATH:mhz00310]
D Metho_2374 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Metho_2357 NAD-dependent aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D Metho_0357 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00220 Arginine biosynthesis [PATH:mhz00220]
D Metho_1970 ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D Metho_1085 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D Metho_1009 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D Metho_1051 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D Metho_0301 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Metho_0307 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Metho_1084 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D Metho_1083 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D Metho_0754 glutamate dehydrogenase/leucine dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D Metho_0198 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_0923 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_0296 acetyltransferase, N-acetylglutamate synthase K00619 argA; amino-acid N-acetyltransferase [EC:2.3.1.1]
D Metho_2211 acetyltransferase, N-acetylglutamate synthase K00619 argA; amino-acid N-acetyltransferase [EC:2.3.1.1]
D Metho_2036 glutamate N-acetyltransferase/amino-acid acetyltransferase K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]
D Metho_0289 acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8]
D Metho_2038 N-acetyl-gamma-glutamyl-phosphate reductase, common form K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]
D Metho_0450 acetylornithine/succinylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
C 00330 Arginine and proline metabolism [PATH:mhz00330]
D Metho_1301 cytosine/adenosine deaminase K03365 FCY1; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21]
D Metho_1360 arginine decarboxylase, pyruvoyl-dependent K02626 pdaD; arginine decarboxylase [EC:4.1.1.19]
D Metho_0170 agmatinase K01480 speB; agmatinase [EC:3.5.3.11]
D Metho_0384 diaminopimelate decarboxylase K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
D Metho_0357 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Metho_2205 pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
D Metho_2029 glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D Metho_2028 gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
D Metho_0198 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_0923 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00340 Histidine metabolism [PATH:mhz00340]
D Metho_0093 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D Metho_0536 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D Metho_0195 phosphoribosyl-ATP pyrophosphohydrolase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
D Metho_2390 phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
D Metho_0092 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D Metho_1722 hisA/hisF family protein K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D Metho_2332 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D Metho_0175 imidazoleglycerol phosphate synthase, cyclase subunit K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D Metho_0091 imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D Metho_0451 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D Metho_1860 histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
D Metho_0357 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00350 Tyrosine metabolism [PATH:mhz00350]
D Metho_0198 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_0923 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_0451 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D Metho_2460 tyrosine decarboxylase MnfA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D Metho_2357 NAD-dependent aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00360 Phenylalanine metabolism [PATH:mhz00360]
D Metho_0535 coenzyme F390 synthetase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30]
D Metho_0361 coenzyme F390 synthetase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30]
D Metho_1893 coenzyme F390 synthetase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30]
D Metho_1775 coenzyme F390 synthetase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30]
D Metho_1773 hypothetical protein K02614 paaI; acyl-CoA thioesterase [EC:3.1.2.-]
D Metho_0198 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_0923 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_0451 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D Metho_0353 NADH:flavin oxidoreductase K10797 enr; 2-enoate reductase [EC:1.3.1.31]
C 00380 Tryptophan metabolism [PATH:mhz00380]
D Metho_2374 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Metho_0357 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Metho_1739 catalase K03781 katE; catalase [EC:1.11.1.6]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:mhz00400]
D Metho_0427 DhnA-type fructose-1,6-bisphosphate aldolase-like enzyme K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D Metho_0254 putative phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Metho_0268 putative phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Metho_0267 putative alternative 3-dehydroquinate synthase K11646 K11646; 3-dehydroquinate synthase II [EC:1.4.1.24]
D Metho_0266 3-dehydroquinate dehydratase, type I K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D Metho_0265 shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D Metho_0506 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D Metho_0727 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D Metho_1672 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D Metho_1004 chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D Metho_2183 anthranilate synthase component I, archaeal clade K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D Metho_2182 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D Metho_2185 anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D Metho_2184 phosphoribosylanthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D Metho_0865 Indole-3-glycerol phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D Metho_0862 tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D Metho_0863 tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D Metho_1857 pyridoxal-phosphate dependent TrpB-like enzyme K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D Metho_0726 chorismate mutase K04093 pheA1; chorismate mutase [EC:5.4.99.5]
D Metho_0264 prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D Metho_1131 prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51]
D Metho_0198 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_0923 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_0451 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:mhz00410]
D Metho_2460 tyrosine decarboxylase MnfA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D Metho_0357 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Metho_1912 hypothetical protein K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
C 00430 Taurine and hypotaurine metabolism
C 00440 Phosphonate and phosphinate metabolism
D Metho_0108 metal-dependent hydrolase, beta-lactamase superfamily I K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]
C 00450 Selenocompound metabolism [PATH:mhz00450]
D Metho_2427 methionine synthase II (cobalamin-independent) K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D Metho_2171 selenocysteine lyase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D Metho_0930 thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D Metho_2371 protein containing C-terminal region/beta chain of methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism
D Metho_2321 glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:mhz00470]
D Metho_2160 ATP-grasp enzyme, D-alanine-D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D Metho_1051 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D Metho_0844 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
C 00480 Glutathione metabolism [PATH:mhz00480]
D Metho_1509 aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D Metho_1041 aminoacyl-histidine dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-]
D Metho_0384 diaminopimelate decarboxylase K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis
C 00550 Peptidoglycan biosynthesis
C 00552 Teichoic acid biosynthesis
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis [PATH:mhz00543]
D Metho_0595 serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D Metho_1735 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:mhz00730]
D Metho_0074 thiamine biosynthesis protein ThiC K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D Metho_1785 thiamine biosynthesis protein ThiC K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D Metho_0714 phosphomethylpyrimidine kinase K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
D Metho_1173 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Metho_2275 cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Metho_0496 thiazole biosynthesis/tRNA modification protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D Metho_1589 hydroxyethylthiazole kinase K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50]
D Metho_1590 thiamine-phosphate pyrophosphorylase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D Metho_2113 thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D Metho_1307 ribosome small subunit-dependent GTPase A K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
D Metho_2001 adenylate kinase family protein K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:mhz00740]
D Metho_2197 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302]
D Metho_0114 3,4-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D Metho_0922 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D Metho_0921 riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D Metho_0115 transcriptional regulator of a riboflavin/FAD biosynthetic operon K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161]
D Metho_0924 cytidyltransferase-related enzyme K14656 ribL; FAD synthetase [EC:2.7.7.2]
D Metho_1589 hydroxyethylthiazole kinase K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50]
D Metho_2230 polyprenyl p-hydroxybenzoate/phenylacrylic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00750 Vitamin B6 metabolism [PATH:mhz00750]
D Metho_0651 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D Metho_1033 pyridoxal 5''-phosphate synthase, synthase subunit Pdx1 K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
D Metho_1034 pyridoxal 5''-phosphate synthase, glutaminase subunit Pdx2 K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C 00760 Nicotinate and nicotinamide metabolism [PATH:mhz00760]
D Metho_0340 aspartate dehydrogenase K06989 nadX; aspartate dehydrogenase [EC:1.4.1.21]
D Metho_0612 quinolinate synthetase complex, A subunit K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D Metho_0339 quinolinate synthetase complex, A subunit K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D Metho_0367 nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D Metho_1380 nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D Metho_0467 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D Metho_2245 nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1]
D Metho_1993 Zn-finger containing NTP pyrophosphohydrolase K03426 NUDT12_13; NAD+ diphosphatase [EC:3.6.1.22]
D Metho_2450 NAD+ synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D Metho_2325 NAD+ synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D Metho_1061 NAD-dependent protein deacetylase, SIR2 family K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313]
D Metho_0887 putative sugar kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D Metho_2357 NAD-dependent aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00770 Pantothenate and CoA biosynthesis [PATH:mhz00770]
D Metho_2355 thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Metho_1791 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Metho_1790 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D Metho_1789 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D Metho_0664 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D Metho_1843 2-dehydropantoate 2-reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D Metho_1911 putative kinase, sugar kinase superfamily K06982 pok; pantoate kinase [EC:2.7.1.169]
D Metho_1912 hypothetical protein K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D Metho_1910 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D Metho_2286 cytidyltransferase-related enzyme K02201 E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D Metho_0556 hypothetical protein K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237]
D Metho_0798 hypothetical protein K06133 LYS5; 4'-phosphopantetheinyl transferase [EC:2.7.8.-]
D Metho_2300 branched-chain amino acid aminotransferase, group I K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Metho_2460 tyrosine decarboxylase MnfA K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D Metho_0357 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00780 Biotin metabolism [PATH:mhz00780]
D Metho_2449 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D Metho_0791 birA, biotin-(acetyl-CoA-carboxylase) ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism
C 00790 Folate biosynthesis [PATH:mhz00790]
D Metho_2319 dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D Metho_1833 queuosine biosynthesis protein QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D Metho_1834 organic radical activating enzyme K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D Metho_1836 queuosine biosynthesis protein QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D Metho_0291 TIGR00294 family protein K17488 mptA; GTP cyclohydrolase IV [EC:3.5.4.39]
D Metho_0452 hypothetical protein K09739 mptD; dihydroneopterin aldolase [EC:4.1.2.25]
D Metho_1547 putative Rossmann fold enzyme K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D Metho_0055 beta-RFAP synthase K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54]
D Metho_2125 metal-dependent hydrolase, beta-lactamase superfamily II K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105]
D Metho_1409 alpha-L-glutamate ligase, RimK family K15740 mptN; tetrahydromethanopterin:alpha-L-glutamate ligase [EC:6.3.2.33]
D Metho_0465 putative molybdenum cofactor biosynthesis protein A, archaeal K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D Metho_0189 molybdenum cofactor biosynthesis protein MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D Metho_0742 molybdopterin-guanine dinucleotide biosynthesis protein MobB K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D Metho_2219 molybdenum cofactor synthesis domain protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D Metho_2225 molybdopterin biosynthesis enzyme K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D Metho_2298 molybdenum cofactor synthesis domain protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D Metho_0803 molybdopterin-guanine dinucleotide biosynthesis protein A K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
C 00670 One carbon pool by folate [PATH:mhz00670]
D Metho_2320 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D Metho_2321 glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Metho_2322 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D Metho_0143 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D Metho_0661 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D Metho_2393 5,10-methylenetetrahydrofolate reductase K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:mhz00860]
D Metho_0813 glutamyl-tRNA synthetase, archaeal and eukaryotic family K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Metho_0824 glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D Metho_0822 glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D Metho_0823 delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D Metho_0821 porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D Metho_1863 uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D Metho_2301 uroporphyrinogen-III decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]
D Metho_0364 uroporphyrinogen-III decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]
D Metho_1862 uroporphyrin-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D Metho_0825 siroheme synthase, N-terminal domain protein K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76]
D Metho_0827 transcriptional regulator K22225 ahbAB; siroheme decarboxylase [EC:4.1.1.111]
D Metho_0826 hypothetical protein K22225 ahbAB; siroheme decarboxylase [EC:4.1.1.111]
D Metho_1864 putative heme d1 biosynthesis radical SAM protein NirJ1 K22226 ahbC; Fe-coproporphyrin III synthase
D Metho_0828 putative heme d1 biosynthesis radical SAM protein NirJ2 K22227 ahbD; AdoMet-dependent heme synthase [EC:1.3.98.6]
D Metho_0734 hypothetical protein K22011 cfbA; sirohydrochlorin cobalto/nickelchelatase [EC:4.99.1.3 4.99.1.11]
D Metho_2189 precorrin-2 methylase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151]
D Metho_2193 precorrin-3B C17-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272]
D Metho_2190 precorrin-4 C11-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271]
D Metho_2191 cobalamin biosynthesis protein CbiG K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12]
D Metho_2192 cobalamin biosynthesis protein CbiG K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12]
D Metho_2294 cobalamin biosynthesis protein CbiD K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195]
D Metho_2188 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196]
D Metho_2293 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289]
D Metho_2194 precorrin isomerase K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60]
D Metho_0464 cobyrinic acid a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
D Metho_0563 Mg chelatase, cobalamin biosynthesis protein CobN K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D Metho_0564 Mg chelatase, cobalamin biosynthesis protein CobN K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D Metho_0562 Mg chelatase, cobalamin biosynthesis protein CobN K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D Metho_2187 cobyric acid synthase CobQ K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10]
D Metho_1541 cobalamin biosynthesis protein CobD K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
D Metho_0085 hypothetical protein K08260 cbiZ; adenosylcobinamide hydrolase [EC:3.5.1.90]
D Metho_1544 GTP:adenosylcobinamide-phosphate guanylyltransferase K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62]
D Metho_1543 cobalamin 5''-phosphate synthase/cobalamin synthase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26]
D Metho_1539 PLP-dependent enzyme, histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase K04720 cobD; threonine-phosphate decarboxylase [EC:4.1.1.81]
D Metho_1540 L-threonine-O-3-phosphate decarboxylase K04720 cobD; threonine-phosphate decarboxylase [EC:4.1.1.81]
D Metho_0541 cobyrinic acid a,c-diamide synthase K22012 cfbB; Ni-sirohydrochlorin a,c-diamide synthase [EC:6.3.5.12]
D Metho_0542 nitrogenase subunit NifH (ATPase) K21610 cfbC; Ni-sirohydrochlorin a,c-diamide reductive cyclase subunit CfbC [EC:6.3.3.7]
D Metho_0543 putative methanogenesis marker 13 metalloprotein K21611 cfbD; Ni-sirohydrochlorin a,c-diamide reductive cyclase subunit CfbD [EC:6.3.3.7]
D Metho_0544 hypothetical protein K21612 cfbE; coenzyme F430 synthetase [EC:6.4.1.9]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:mhz00130]
D Metho_2230 polyprenyl p-hydroxybenzoate/phenylacrylic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D Metho_1023 putative NADPH-quinone reductase (modulator of drug activity B) K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:mhz00900]
D Metho_2374 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Metho_2375 hydroxymethylglutaryl-CoA synthase, putative K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D Metho_0696 NADP-dependent hydroxymethylglutaryl-CoA reductase K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
D Metho_1635 mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D Metho_1634 putative archaeal kinase K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26]
D Metho_2163 hypothetical protein K25517 acnX1; phosphomecalonate degydratase large subunit [EC:4.2.1.182]
D Metho_2164 hypothetical protein K09128 acnX2; phosphomecalonate degydratase small subunit [EC:4.2.1.182]
D Metho_2162 UbiD family decarboxylase K25518 E4.1.1.126; anhydromevalonate phosphate decarboxylase [EC:4.1.1.126]
D Metho_2230 polyprenyl p-hydroxybenzoate/phenylacrylic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D Metho_1633 isopentenyl-diphosphate delta-isomerase, type 2 K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D Metho_1631 geranylgeranyl pyrophosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D Metho_0831 geranylgeranyl pyrophosphate synthase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D Metho_0104 undecaprenyl pyrophosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D Metho_1987 undecaprenyl diphosphate synthase K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis
D Metho_1850 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Metho_1847 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis [PATH:mhz00332]
D Metho_2029 glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D Metho_2028 gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
C 00261 Monobactam biosynthesis [PATH:mhz00261]
D Metho_2083 aspartate kinase, monofunctional class K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Metho_0124 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D Metho_0279 dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D Metho_0280 dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:mhz00521]
D Metho_2209 phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Metho_2257 myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D Metho_0888 inositol monophosphatase/fructose-1,6-bisphosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D Metho_1850 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Metho_1847 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis
D Metho_1850 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Metho_1847 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C 00401 Novobiocin biosynthesis [PATH:mhz00401]
D Metho_0264 prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D Metho_0198 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_0923 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_0451 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D Metho_2183 anthranilate synthase component I, archaeal clade K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D Metho_2182 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D Metho_2449 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
C 00999 Biosynthesis of various plant secondary metabolites [PATH:mhz00999]
D Metho_0094 archaeal S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D Metho_0265 shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation
D Metho_2374 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00627 Aminobenzoate degradation [PATH:mhz00627]
D Metho_0495 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D Metho_2230 polyprenyl p-hydroxybenzoate/phenylacrylic acid decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation [PATH:mhz00625]
D Metho_0357 NAD-dependent aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation [PATH:mhz00633]
D Metho_1412 carbon-monoxide dehydrogenase, catalytic subunit K00198 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4]
D Metho_2440 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Metho_2441 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D Metho_2438 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D Metho_2439 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:mhz03020]
D Metho_1919 DNA-directed RNA polymerase subunit B K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D Metho_1918 DNA-directed RNA polymerase, beta subunit/140 kD subunit K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D Metho_1920 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D Metho_1921 DNA-directed RNA polymerase, subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D Metho_1989 DNA-directed RNA polymerase, alpha subunit/40 kD subunit K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D Metho_2238 DNA-directed RNA polymerase, subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D Metho_0554 DNA-directed RNA polymerase subunit E' K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D Metho_0718 hypothetical protein K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D Metho_1917 DNA-directed RNA polymerase, subunit H, RpoH/RPB5 K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D Metho_1638 DNA-directed RNA polymerase, subunit K/omega K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D Metho_1640 DNA-directed RNA polymerase, subunit N (RpoN/RPB10) K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D Metho_1888 DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger) K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
C 03022 Basal transcription factors [PATH:mhz03022]
D Metho_1278 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB
D Metho_0072 TATA-box binding protein (TBP), component of TFIID and TFIIIB K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Metho_0989 transcription initiation factor IIE, alpha subunit K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D Metho_0058 DNA helicase, Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:mhz03010]
D Metho_1637 ribosomal protein Sa/S2 K02967 RP-S2; small subunit ribosomal protein S2
D Metho_2019 ribosomal protein S3, eukaryotic/archaeal type K02982 RP-S3; small subunit ribosomal protein S3
D Metho_1991 ribosomal protein S4/S9 K02986 RP-S4; small subunit ribosomal protein S4
D Metho_2005 ribosomal protein S5/S2 K02988 RP-S5; small subunit ribosomal protein S5
D Metho_1925 ribosomal protein S7/S5 K02992 RP-S7; small subunit ribosomal protein S7
D Metho_2010 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D Metho_1641 archaeal ribosomal protein S9P K02996 RP-S9; small subunit ribosomal protein S9
D Metho_1928 ribosomal protein S10/S20 K02946 RP-S10; small subunit ribosomal protein S10
D Metho_1990 archaeal ribosomal protein S11P K02948 RP-S11; small subunit ribosomal protein S11
D Metho_1924 ribosomal protein S23 K02950 RP-S12; small subunit ribosomal protein S12
D Metho_1992 archaeal ribosomal protein S13P K02952 RP-S13; small subunit ribosomal protein S13
D Metho_2011 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D Metho_1851 ribosomal protein S15P/S13E K02956 RP-S15; small subunit ribosomal protein S15
D Metho_2016 archaeal ribosomal protein S17P K02961 RP-S17; small subunit ribosomal protein S17
D Metho_2021 ribosomal protein S19/S15 K02965 RP-S19; small subunit ribosomal protein S19
D Metho_1839 ribosomal protein S3AE K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D Metho_2013 ribosomal protein S4E K02987 RP-S4e; small subunit ribosomal protein S4e
D Metho_1520 ribosomal protein S6E (S10) K02991 RP-S6e; small subunit ribosomal protein S6e
D Metho_0705 ribosomal protein S8.e K02995 RP-S8e; small subunit ribosomal protein S8e
D Metho_0278 ribosomal protein S17E K02962 RP-S17e; small subunit ribosomal protein S17e
D Metho_0853 ribosomal protein S19E (S16A) K02966 RP-S19e; small subunit ribosomal protein S19e
D Metho_0557 ribosomal protein S24E K02974 RP-S24e; small subunit ribosomal protein S24e
D Metho_0398 ribosomal protein S27E K02978 RP-S27e; small subunit ribosomal protein S27e
D Metho_0558 ribosomal protein S27AE K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D Metho_1516 ribosomal protein S28E/S33 K02979 RP-S28e; small subunit ribosomal protein S28e
D Metho_2348 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D Metho_2022 ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D Metho_2025 archaeal ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D Metho_2012 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D Metho_2009 archaeal ribosomal protein L6P K02933 RP-L6; large subunit ribosomal protein L6
D Metho_2347 ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D Metho_2349 ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D Metho_2346 50S ribosomal protein L12P K02869 RP-L12; large subunit ribosomal protein L12
D Metho_1642 ribosomal protein L13, archaeal/eukaryotic K02871 RP-L13; large subunit ribosomal protein L13
D Metho_2015 50S ribosomal protein L14P K02874 RP-L14; large subunit ribosomal protein L14
D Metho_2003 ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D Metho_2006 ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D Metho_2020 ribosomal protein L22/L17 K02890 RP-L22; large subunit ribosomal protein L22
D Metho_2023 archaeal ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D Metho_2014 ribosomal protein L24p/L26e, archaeal/eukaryotic K02895 RP-L24; large subunit ribosomal protein L24
D Metho_2018 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D Metho_2004 50S ribosomal protein L30P, archaeal K02907 RP-L30; large subunit ribosomal protein L30
D Metho_2024 50S ribosomal protein L4P K02930 RP-L4e; large subunit ribosomal protein L4e
D Metho_1515 50S ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D Metho_2218 ribosomal protein L10.e K02866 RP-L10e; large subunit ribosomal protein L10e
D Metho_1878 ribosomal protein L15E K02877 RP-L15e; large subunit ribosomal protein L15e
D Metho_1643 ribosomal protein L18E K02883 RP-L18e; large subunit ribosomal protein L18e
D Metho_2007 ribosomal protein L19E K02885 RP-L19e; large subunit ribosomal protein L19e
D Metho_0717 ribosomal protein L21E K02889 RP-L21e; large subunit ribosomal protein L21e
D Metho_1517 ribosomal protein L24E K02896 RP-L24e; large subunit ribosomal protein L24e
D Metho_1922 ribosomal protein L30E K02908 RP-L30e; large subunit ribosomal protein L30e
D Metho_0857 ribosomal protein L31E K02910 RP-L31e; large subunit ribosomal protein L31e
D Metho_2008 ribosomal protein L32E K02912 RP-L32e; large subunit ribosomal protein L32e
D Metho_0712 ribosomal protein L37E K02922 RP-L37e; large subunit ribosomal protein L37e
D Metho_1887 ribosomal protein L37a K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D Metho_0856 ribosomal protein L39E K02924 RP-L39e; large subunit ribosomal protein L39e
D Metho_0330 ribosomal protein L40E K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D Metho_0399 ribosomal protein L44E K02929 RP-L44e; large subunit ribosomal protein L44e
D Metho_0859 ribosomal protein L20A (L18A) K02944 RP-LX; large subunit ribosomal protein LX
D Metho_0232 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Metho_2401 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Metho_2399 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Metho_0234 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Metho_0236 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Metho_2397 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:mhz00970]
D Metho_0233 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Metho_2400 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Metho_0935 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Metho_0691 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Metho_0102 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Metho_0297 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Metho_1755 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Metho_1930 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Metho_2302 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Metho_1181 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D Metho_0096 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D Metho_0235 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D Metho_0608 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D Metho_2398 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D Metho_0601 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D Metho_1165 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Metho_2338 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Metho_2722 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Metho_1557 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Metho_0619 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Metho_1690 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Metho_0625 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Metho_2242 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Metho_0710 tRNA-His K14226 tRNA-His; tRNA His
D Metho_0692 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D Metho_0629 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Metho_1313 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Metho_1751 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Metho_1969 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Metho_1988 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Metho_2432 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Metho_1916 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Metho_0219 tRNA-Met K14230 tRNA-Met; tRNA Met
D Metho_0273 tRNA-Met K14230 tRNA-Met; tRNA Met
D Metho_1180 tRNA-Met K14230 tRNA-Met; tRNA Met
D Metho_1689 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D Metho_0113 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Metho_2229 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Metho_1639 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Metho_0207 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Metho_1997 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Metho_0960 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Metho_1824 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Metho_0442 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Metho_1271 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Metho_1273 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Metho_1874 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D Metho_0095 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D Metho_1688 tRNA-Val K14237 tRNA-Val; tRNA Val
D Metho_0257 tRNA-Val K14237 tRNA-Val; tRNA Val
D Metho_1016 tRNA-Val K14237 tRNA-Val; tRNA Val
D Metho_0813 glutamyl-tRNA synthetase, archaeal and eukaryotic family K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Metho_0332 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D Metho_0331 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D Metho_0333 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D Metho_1010 glutamyl-tRNA(Gln) amidotransferase, subunit D K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7]
D Metho_1081 glutamyl-tRNA(Gln) amidotransferase, subunit E K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7]
D Metho_0470 alanine--tRNA ligase/alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Metho_1011 aspartyl-tRNA synthetase, archaeal type K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D Metho_0253 glycyl-tRNA synthetase, dimeric type K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Metho_0494 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Metho_1840 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Metho_0248 O-phosphoseryl-tRNA(Cys) synthetase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
D Metho_0600 Sep-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
D Metho_2240 Sep-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
D Metho_0101 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Metho_2371 protein containing C-terminal region/beta chain of methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Metho_1867 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Metho_0579 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Metho_1546 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Metho_0184 lysyl-tRNA synthetase, archaeal and spirochete K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D Metho_0022 pyrrolysyl-tRNA synthetase, C-terminal region/pyrrolysyl-tRNA synthetase, N-terminal region K11627 pylS; pyrrolysyl-tRNA synthetase [EC:6.1.1.26]
D Metho_0040 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Metho_1872 prolyl-tRNA synthetase, family I K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Metho_1856 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Metho_2213 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Metho_1056 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Metho_2059 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Metho_2214 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:mhz03060]
D Metho_2002 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D Metho_2076 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D Metho_2077 preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D Metho_0271 signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D Metho_0208 Eukaryotic type signal recognition particle RNA K01983 ffs; SRP RNA
D Metho_0861 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D Metho_2351 protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D Metho_2102 signal recognition particle 19 kDa protein K03105 SRP19; signal recognition particle subunit SRP19
D Metho_0002 signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:mhz04122]
D Metho_1173 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Metho_2275 cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Metho_1171 putative redox protein, regulator of disulfide bond formation K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D Metho_0742 molybdopterin-guanine dinucleotide biosynthesis protein MobB K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D Metho_0465 putative molybdenum cofactor biosynthesis protein A, archaeal K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D Metho_2226 MoaD family protein K03636 moaD; sulfur-carrier protein
D Metho_1591 dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]
D Metho_0189 molybdenum cofactor biosynthesis protein MoaC K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D Metho_2219 molybdenum cofactor synthesis domain protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D Metho_0496 thiazole biosynthesis/tRNA modification protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D Metho_0594 sulfur transfer protein involved in thiamine biosynthesis K03154 thiS; sulfur carrier protein
D Metho_0885 hypothetical protein K03154 thiS; sulfur carrier protein
C 03050 Proteasome [PATH:mhz03050]
D Metho_0620 26S proteasome subunit P45 family K03420 psmR; proteasome regulatory subunit
D Metho_2207 26S proteasome subunit P45 family K03420 psmR; proteasome regulatory subunit
D Metho_1882 proteasome endopeptidase complex, archaeal, alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Metho_0991 proteasome endopeptidase complex, archaeal, beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C 03018 RNA degradation [PATH:mhz03018]
D Metho_2237 putative RNA-binding protein (consists of S1 domain and a Zn-ribbon domain) K07573 CSL4; exosome complex component CSL4
D Metho_1884 RNA-binding protein Rrp4 (containing S1 domain and KH domain) K03679 RRP4; exosome complex component RRP4
D Metho_1886 RNase PH-related exoribonuclease K12589 RRP42; exosome complex component RRP42
D Metho_1885 archaeal exosome-like complex exonuclease 1 K11600 RRP41; exosome complex component RRP41
D Metho_0369 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Metho_1929 DNA/RNA helicase, superfamily II K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]
D Metho_1306 DNA/RNA helicase, superfamily II K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D Metho_1178 DNA/RNA helicase, superfamily II K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D Metho_0286 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D Metho_1632 putative hydrolase of the metallo-beta-lactamase superfamily K12574 rnj; ribonuclease J [EC:3.1.-.-]
D Metho_0943 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D Metho_0739 chaperonin GroL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Metho_0782 polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:mhz03030]
D Metho_0682 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D Metho_2413 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D Metho_1052 ribonuclease H, mammalian HI/archaeal HII subfamily K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Metho_2471 ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4]
D Metho_2679 DNA polymerase elongation subunit (family B) K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D Metho_0220 DNA polymerase elongation subunit (family B) K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D Metho_0003 archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D Metho_1664 DNA polymerase type II, large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D Metho_0796 putative ATPase involved in replication control, Cdc46/Mcm family K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D Metho_2482 putative ATPase involved in replication control, Cdc46/Mcm family K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D Metho_0403 DNA primase, eukaryotic-type, small subunit, putative K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D Metho_0459 DNA primase, large subunit K18882 priL; DNA primase large subunit
D Metho_2417 single-stranded DNA-binding protein K07466 RFA1; replication factor A1
D Metho_0458 proliferating cell nuclear antigen PCNA K04802 PCNA; proliferating cell nuclear antigen
D Metho_0419 DNA polymerase III, gamma/tau subunit K04801 rfcS; replication factor C small subunit
D Metho_2075 DNA polymerase III, gamma/tau subunit K04801 rfcS; replication factor C small subunit
D Metho_0659 DNA polymerase III, gamma/tau subunit K04800 rfcL; replication factor C large subunit
D Metho_0147 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Metho_1282 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Metho_1681 ATP-dependent DNA ligase I K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03410 Base excision repair [PATH:mhz03410]
D Metho_2033 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D Metho_0260 putative endoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D Metho_2442 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D Metho_0458 proliferating cell nuclear antigen PCNA K04802 PCNA; proliferating cell nuclear antigen
D Metho_0147 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Metho_1282 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Metho_1681 ATP-dependent DNA ligase I K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Metho_1844 uracil-DNA glycosylase, family 4 K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D Metho_1742 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D Metho_2288 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D Metho_1105 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_2670 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_1846 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_2068 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
C 03420 Nucleotide excision repair [PATH:mhz03420]
D Metho_1950 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
D Metho_0624 excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
D Metho_2065 excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C
D Metho_2592 DNA/RNA helicase, superfamily I K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D Metho_0058 DNA helicase, Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D Metho_2417 single-stranded DNA-binding protein K07466 RFA1; replication factor A1
D Metho_0458 proliferating cell nuclear antigen PCNA K04802 PCNA; proliferating cell nuclear antigen
D Metho_1681 ATP-dependent DNA ligase I K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03430 Mismatch repair [PATH:mhz03430]
D Metho_2296 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Metho_0090 mismatch repair ATPase (MutS family) K07456 mutS2; DNA mismatch repair protein MutS2
D Metho_2295 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Metho_2592 DNA/RNA helicase, superfamily I K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D Metho_1977 exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D Metho_1976 exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D Metho_1105 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_2670 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_1846 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_2068 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_0458 proliferating cell nuclear antigen PCNA K04802 PCNA; proliferating cell nuclear antigen
D Metho_2417 single-stranded DNA-binding protein K07466 RFA1; replication factor A1
D Metho_1681 ATP-dependent DNA ligase I K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03440 Homologous recombination [PATH:mhz03440]
D Metho_1105 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_2670 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_1846 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_2068 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_0321 putative transcriptional regulator with HTH domain K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D Metho_1369 putative transcriptional regulator with HTH domain K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D Metho_2039 putative transcriptional regulator with HTH domain K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D Metho_1393 putative transcriptional regulator with HTH domain K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D Metho_2417 single-stranded DNA-binding protein K07466 RFA1; replication factor A1
C 03450 Non-homologous end-joining
D Metho_0147 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Metho_1282 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
D Metho_0555 DNA-directed RNA polymerase, subunit E' K15171 SUPT4H1; transcription elongation factor SPT4
D Metho_2350 ribosomal protein L24p/L26e, archaeal K15172 SUPT5H; transcription elongation factor SPT5
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:mhz02010]
D Metho_2116 ABC transporter, substrate-binding protein, aliphatic sulfonates family K15553 ssuA; sulfonate transport system substrate-binding protein
D Metho_2117 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component K15554 ssuC; sulfonate transport system permease protein
D Metho_2118 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D Metho_2316 molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 modA; molybdate transport system substrate-binding protein
D Metho_2315 molybdate ABC transporter, permease protein K02018 modB; molybdate transport system permease protein
D Metho_2314 ABC-type spermidine/putrescine transport system, ATPase component K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5]
D Metho_1123 periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) K05845 opuC; osmoprotectant transport system substrate-binding protein
D Metho_1120 ABC-type proline/glycine betaine transport system, permease component K05846 opuBD; osmoprotectant transport system permease protein
D Metho_1121 ABC-type proline/glycine betaine transport system, permease component K05846 opuBD; osmoprotectant transport system permease protein
D Metho_1122 glycine betaine/L-proline transport ATP binding subunit K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]
D Metho_0225 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein
D Metho_0224 phosphate ABC transporter, permease protein PstC K02037 pstC; phosphate transport system permease protein
D Metho_0223 phosphate ABC transporter, permease protein PstA K02038 pstA; phosphate transport system permease protein
D Metho_0222 phosphate ABC transporter, ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D Metho_1459 periplasmic component of amino acid ABC-type transporter/signal transduction system K10036 glnH; glutamine transport system substrate-binding protein
D Metho_1160 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family K10037 glnP; glutamine transport system permease protein
D Metho_1159 ABC-type polar amino acid transport system, ATPase component K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1]
D Metho_2136 ABC-type metal ion transport system, periplasmic component/surface adhesin K09815 znuA; zinc transport system substrate-binding protein
D Metho_2138 ABC-type Mn2+/Zn2+ transport system, permease component K09816 znuB; zinc transport system permease protein
D Metho_2137 ATPase component of Mn/Zn ABC-type transporter K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D Metho_0508 hypothetical protein K02009 cbiN; cobalt/nickel transport protein
D Metho_2291 ABC-type cobalt transport system, periplasmic component K02009 cbiN; cobalt/nickel transport protein
D Metho_0507 ABC-type Co2+ transport system, permease component K02007 cbiM; cobalt/nickel transport system permease protein
D Metho_2292 cobalamin biosynthesis protein CbiM K02007 cbiM; cobalt/nickel transport system permease protein
D Metho_0522 cobalt ABC transporter, permease protein CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein
D Metho_2290 cobalt ABC transporter, permease protein CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein
D Metho_0523 cobalt transport protein ATP-binding subunit K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D Metho_2289 cobalt transport protein ATP-binding subunit K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D Metho_2308 hypothetical protein K03523 bioY; biotin transport system substrate-specific component
D Metho_2311 ABC-type cobalt transport system, permease component CbiQ K16785 ecfT; energy-coupling factor transport system permease protein
D Metho_2309 ABC-type cobalt transport system, ATPase component K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D Metho_2310 ABC-type cobalt transport system, ATPase component K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D Metho_1285 ABC-type polysaccharide/polyol phosphate export systems, permease component K09690 wzm; homopolymeric O-antigen transport system permease protein
D Metho_1286 ABC-type polysaccharide/polyol phosphate transport system, ATPase component K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14]
D Metho_0110 ABC-type polysaccharide/polyol phosphate export systems, permease component K09694 nodJ; lipooligosaccharide transport system permease protein
D Metho_0111 ABC-type multidrug transport system, ATPase component K09695 nodI; lipooligosaccharide transport system ATP-binding protein
D Metho_1561 ABC-type transport system involved in cytochrome c biogenesis, permease component K02195 ccmC; heme exporter protein C
D Metho_1562 ABC-type transport system involved in cytochrome c biogenesis, permease component K02194 ccmB; heme exporter protein B
D Metho_1563 ABC-type multidrug transport system, ATPase component K02193 ccmA; heme exporter protein A [EC:7.6.2.5]
C 02060 Phosphotransferase system (PTS)
C 03070 Bacterial secretion system [PATH:mhz03070]
D Metho_2076 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D Metho_2077 preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D Metho_2002 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D Metho_0861 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D Metho_0271 signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:mhz02020]
D Metho_1007 PAS domain S-box K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D Metho_0225 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein
D Metho_0521 hypothetical protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
D Metho_1905 hypothetical protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
D Metho_0751 Triphosphoribosyl-dephospho-CoA synthetase K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
D Metho_1065 nitrogen regulatory protein PII K04751 glnB; nitrogen regulatory protein P-II 1
D Metho_0301 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Metho_0307 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Metho_2374 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Metho_1433 methylase of chemotaxis methyl-accepting protein K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D Metho_0962 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein
D Metho_1021 chemotaxis signal transduction protein K03408 cheW; purine-binding chemotaxis protein CheW
D Metho_1431 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D Metho_1429 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Metho_1430 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D Metho_0518 Cbb3-type cytochrome oxidase, subunit 1 K15862 ccoNO; cytochrome c oxidase cbb3-type subunit I/II [EC:7.1.1.9]
D Metho_1979 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D Metho_1474 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D Metho_1796 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
D Metho_0384 diaminopimelate decarboxylase K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:mhz02024]
D Metho_2183 anthranilate synthase component I, archaeal clade K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D Metho_2182 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D Metho_1804 conserved repeat protein K20276 bapA; large repetitive protein
D Metho_2002 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D Metho_0861 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D Metho_0271 signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis [PATH:mhz02030]
D Metho_0962 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein
D Metho_1431 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D Metho_1021 chemotaxis signal transduction protein K03408 cheW; purine-binding chemotaxis protein CheW
D Metho_1429 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Metho_1432 chemotaxis protein CheC, inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC
D Metho_1434 chemotaxis protein CheC, inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC
D Metho_1437 chemotaxis protein CheC, inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC
D Metho_1430 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D Metho_1435 chemotaxis protein K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]
D Metho_1433 methylase of chemotaxis methyl-accepting protein K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
C 02040 Flagellar assembly
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells [PATH:mhz04820]
D Metho_1783 P-type ATPase, translocating K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
D Metho_0369 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance
C 01502 Vancomycin resistance [PATH:mhz01502]
D Metho_2160 ATP-grasp enzyme, D-alanine-D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:mhz01503]
D Metho_0521 hypothetical protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
D Metho_1905 hypothetical protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:mhz01000]
C 01001 Protein kinases [BR:mhz01001]
D Metho_0570 Kae1-associated kinase Bud32 K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D Metho_0230 serine/threonine protein kinase involved in cell cycle control K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D Metho_0800 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain protein K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D Metho_1007 PAS domain S-box K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D Metho_1431 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:mhz01009]
D Metho_2217 translation initiation factor aIF-2, beta subunit, putative K03238 EIF2S2; translation initiation factor 2 subunit 2
D Metho_0242 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 01002 Peptidases and inhibitors [BR:mhz01002]
D Metho_0284 prepilin signal peptidase PulO-like peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D Metho_0287 GMP synthase, glutamine-hydrolyzing, C-terminal domain or B subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Metho_0270 GMP synthase, glutamine-hydrolyzing, N-terminal domain or A subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Metho_0711 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D Metho_1849 glucosamine--fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D Metho_1311 putative intracellular protease/amidase K05520 yhbO; deglycase [EC:3.5.1.124]
D Metho_0455 putative membrane protein K24447 artA; archaeosortase A [EC:3.4.22.-]
D Metho_0849 CAAX amino terminal protease family K07052 K07052; CAAX protease family protein
D Metho_1500 CAAX amino terminal protease family K07052 K07052; CAAX protease family protein
D Metho_1594 CAAX amino terminal protease family K07052 K07052; CAAX protease family protein
D Metho_1509 aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D Metho_1041 aminoacyl-histidine dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-]
D Metho_0153 methionine aminopeptidase, type II K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D Metho_0152 Xaa-Pro aminopeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D Metho_0463 Zn-dependent protease with chaperone function K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D Metho_1674 Zn-dependent protease with chaperone function K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D Metho_2263 subtilisin-like serine protease K01342 aprE; subtilisin [EC:3.4.21.62]
D Metho_1383 hypothetical protein K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D Metho_1577 ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D Metho_1686 lon-related putative ATP-dependent protease K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53]
D Metho_0002 signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D Metho_2368 signal peptide peptidase SppA, 36K type K04773 sppA; protease IV [EC:3.4.21.-]
D Metho_0974 putative membrane protein K07059 K07059; rhomboid family protein
D Metho_1882 proteasome endopeptidase complex, archaeal, alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Metho_0991 proteasome endopeptidase complex, archaeal, beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D Metho_0180 collagenase-like protease K08303 prtC; U32 family peptidase [EC:3.4.-.-]
D Metho_1345 collagenase-like protease K08303 prtC; U32 family peptidase [EC:3.4.-.-]
D Metho_1684 putative Zn-dependent protease-like protein K03592 pmbA; PmbA protein
D Metho_1685 putative Zn-dependent protease-like protein K03568 tldD; TldD protein
C 01003 Glycosyltransferases [BR:mhz01003]
D Metho_0073 glycosyl transferase K23684 aglJ; dolichol-phosphate hexosyltransferase [EC:2.4.1.-]
D Metho_0214 putative membrane protein, required for N-linked glycosylation K21306 aglB; dolichyl-phosphooligosaccharide-protein glycotransferase [EC:2.4.99.21]
D Metho_0482 putative membrane protein, required for N-linked glycosylation K21306 aglB; dolichyl-phosphooligosaccharide-protein glycotransferase [EC:2.4.99.21]
D Metho_1483 glycosyltransferase K16148 glgM; alpha-maltose-1-phosphate synthase [EC:2.4.1.342]
C 01005 Lipopolysaccharide biosynthesis proteins [BR:mhz01005]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:mhz01011]
D Metho_2160 ATP-grasp enzyme, D-alanine-D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D Metho_0455 putative membrane protein K24447 artA; archaeosortase A [EC:3.4.22.-]
C 01004 Lipid biosynthesis proteins [BR:mhz01004]
D Metho_2449 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D Metho_1338 DNA-binding protein, excisionase family K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2047 acyl-CoA synthetase/AMP-acid ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_2385 acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Metho_0585 ADP-forming acetyl coenzyme A synthetase K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:mhz01006]
D Metho_1631 geranylgeranyl pyrophosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D Metho_0831 geranylgeranyl pyrophosphate synthase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D Metho_0104 undecaprenyl pyrophosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 01007 Amino acid related enzymes [BR:mhz01007]
D Metho_0184 lysyl-tRNA synthetase, archaeal and spirochete K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D Metho_0813 glutamyl-tRNA synthetase, archaeal and eukaryotic family K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Metho_2059 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Metho_2214 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D Metho_0101 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Metho_0040 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Metho_2371 protein containing C-terminal region/beta chain of methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Metho_1546 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Metho_1867 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Metho_0579 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Metho_1011 aspartyl-tRNA synthetase, archaeal type K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D Metho_1856 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Metho_0022 pyrrolysyl-tRNA synthetase, C-terminal region/pyrrolysyl-tRNA synthetase, N-terminal region K11627 pylS; pyrrolysyl-tRNA synthetase [EC:6.1.1.26]
D Metho_0253 glycyl-tRNA synthetase, dimeric type K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Metho_1840 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Metho_1872 prolyl-tRNA synthetase, family I K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Metho_0494 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Metho_0470 alanine--tRNA ligase/alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Metho_0248 O-phosphoseryl-tRNA(Cys) synthetase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
D Metho_2213 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Metho_1056 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Metho_0198 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_0923 aspartate/tyrosine/aromatic aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Metho_1006 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]
D Metho_0703 aspartate/tyrosine/aromatic aminotransferase K10907 K10907; aminotransferase [EC:2.6.1.-]
D Metho_0451 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D Metho_0450 acetylornithine/succinylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D Metho_0822 glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D Metho_2300 branched-chain amino acid aminotransferase, group I K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:mhz00194]
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:mhz03000]
D Metho_2417 single-stranded DNA-binding protein K07466 RFA1; replication factor A1
D Metho_2701 DNA-methyltransferase Dcm K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D Metho_2718 site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D Metho_0072 TATA-box binding protein (TBP), component of TFIID and TFIIIB K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Metho_2228 DNA gyrase inhibitor K13652 K13652; AraC family transcriptional regulator
D Metho_1968 transcriptional regulator K09017 rutR; TetR/AcrR family transcriptional regulator
D Metho_1077 transcriptional regulator K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D Metho_1457 transcriptional regulator K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D Metho_1741 Fe2+/Zn2+ uptake regulation protein K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D Metho_2264 Fe2+/Zn2+ uptake regulation protein K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator
D Metho_2266 putative transcriptional regulator K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor
D Metho_0613 putative transcriptional regulator K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor
D Metho_1421 putative transcriptional regulator K07721 K07721; ArsR family transcriptional regulator
D Metho_2135 Mn-dependent transcriptional regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D Metho_0767 Mn-dependent transcriptional regulator K11924 mntR; DtxR family transcriptional regulator, manganese transport regulator
D Metho_0791 birA, biotin-(acetyl-CoA-carboxylase) ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D Metho_0324 hypothetical protein K09720 nrpRI; HTH-type transcriptional regulator, global nitrogen regulator NrpRI
D Metho_1036 putative transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D Metho_2157 putative transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D Metho_1349 putative transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D Metho_2327 orotate phosphoribosyltransferase-like enzyme K26599 gfcR; HTH-type transcriptional regulator, activator of D-glucose/D-fructose catabolism
D Metho_2312 molybdenum-binding protein K02019 modE; molybdate transport system regulatory protein
D Metho_2595 CRISPR locus-related DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3
D Metho_2323 putative transcriptional regulator K07728 K07728; putative transcriptional regulator
D Metho_2313 putative transcriptional regulator K07729 K07729; putative transcriptional regulator
D Metho_0433 putative transcriptional regulator K07730 K07730; putative transcriptional regulator
D Metho_2376 putative transcriptional regulator K07731 K07731; putative transcriptional regulator
D Metho_2267 putative transcriptional regulator with CopG/Arc/MetJ DNA-binding domain and metal-binding domain K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D Metho_0864 putative stress-responsive transcriptional regulator K03973 pspC; phage shock protein C
C 03021 Transcription machinery [BR:mhz03021]
D Metho_1278 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB
D Metho_0072 TATA-box binding protein (TBP), component of TFIID and TFIIIB K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Metho_0989 transcription initiation factor IIE, alpha subunit K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D Metho_0058 DNA helicase, Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D Metho_0555 DNA-directed RNA polymerase, subunit E' K15171 SUPT4H1; transcription elongation factor SPT4
D Metho_2350 ribosomal protein L24p/L26e, archaeal K15172 SUPT5H; transcription elongation factor SPT5
D Metho_1923 NusA family KH domain protein K02600 nusA; transcription termination/antitermination protein NusA
D Metho_1920 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D Metho_1921 DNA-directed RNA polymerase, subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D Metho_1919 DNA-directed RNA polymerase subunit B K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D Metho_1918 DNA-directed RNA polymerase, beta subunit/140 kD subunit K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D Metho_1989 DNA-directed RNA polymerase, alpha subunit/40 kD subunit K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D Metho_0554 DNA-directed RNA polymerase subunit E' K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D Metho_0718 hypothetical protein K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D Metho_1917 DNA-directed RNA polymerase, subunit H, RpoH/RPB5 K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D Metho_1638 DNA-directed RNA polymerase, subunit K/omega K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D Metho_2238 DNA-directed RNA polymerase, subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D Metho_1640 DNA-directed RNA polymerase, subunit N (RpoN/RPB10) K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D Metho_1888 DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger) K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
D Metho_0457 transcription factor S, archaeal K03057 tfs; transcription factor S
C 03019 Messenger RNA biogenesis [BR:mhz03019]
D Metho_0555 DNA-directed RNA polymerase, subunit E' K15171 SUPT4H1; transcription elongation factor SPT4
D Metho_2350 ribosomal protein L24p/L26e, archaeal K15172 SUPT5H; transcription elongation factor SPT5
D Metho_0532 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Metho_2282 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Metho_0405 putative translation factor pelota K06965 PELO; protein pelota
D Metho_0039 peptide chain release factor eRF/aRF, subunit 1 K03265 ETF1; peptide chain release factor subunit 1
D Metho_1927 translation elongation factor EF-1 alpha K03231 EEF1A; elongation factor 1-alpha
D Metho_2237 putative RNA-binding protein (consists of S1 domain and a Zn-ribbon domain) K07573 CSL4; exosome complex component CSL4
D Metho_1884 RNA-binding protein Rrp4 (containing S1 domain and KH domain) K03679 RRP4; exosome complex component RRP4
D Metho_1885 archaeal exosome-like complex exonuclease 1 K11600 RRP41; exosome complex component RRP41
D Metho_1886 RNase PH-related exoribonuclease K12589 RRP42; exosome complex component RRP42
D Metho_1632 putative hydrolase of the metallo-beta-lactamase superfamily K12574 rnj; ribonuclease J [EC:3.1.-.-]
D Metho_1929 DNA/RNA helicase, superfamily II K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]
D Metho_1306 DNA/RNA helicase, superfamily II K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D Metho_1178 DNA/RNA helicase, superfamily II K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D Metho_0286 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D Metho_0369 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Metho_0943 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D Metho_0739 chaperonin GroL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Metho_0782 polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
D Metho_1551 DNA/RNA helicase, superfamily II K03725 K03725; putative ATP-dependent RNA helicase [EC:5.6.2.-]
C 03041 Spliceosome [BR:mhz03041]
D Metho_1870 ZPR1-related zinc finger protein K06874 ZPR1; zinc finger protein ZPR1
C 03011 Ribosome [BR:mhz03011]
D Metho_1839 ribosomal protein S3AE K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D Metho_2013 ribosomal protein S4E K02987 RP-S4e; small subunit ribosomal protein S4e
D Metho_1520 ribosomal protein S6E (S10) K02991 RP-S6e; small subunit ribosomal protein S6e
D Metho_0705 ribosomal protein S8.e K02995 RP-S8e; small subunit ribosomal protein S8e
D Metho_0278 ribosomal protein S17E K02962 RP-S17e; small subunit ribosomal protein S17e
D Metho_0853 ribosomal protein S19E (S16A) K02966 RP-S19e; small subunit ribosomal protein S19e
D Metho_0557 ribosomal protein S24E K02974 RP-S24e; small subunit ribosomal protein S24e
D Metho_0398 ribosomal protein S27E K02978 RP-S27e; small subunit ribosomal protein S27e
D Metho_0558 ribosomal protein S27AE K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D Metho_1516 ribosomal protein S28E/S33 K02979 RP-S28e; small subunit ribosomal protein S28e
D Metho_2024 50S ribosomal protein L4P K02930 RP-L4e; large subunit ribosomal protein L4e
D Metho_1515 50S ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D Metho_2218 ribosomal protein L10.e K02866 RP-L10e; large subunit ribosomal protein L10e
D Metho_1878 ribosomal protein L15E K02877 RP-L15e; large subunit ribosomal protein L15e
D Metho_1643 ribosomal protein L18E K02883 RP-L18e; large subunit ribosomal protein L18e
D Metho_2007 ribosomal protein L19E K02885 RP-L19e; large subunit ribosomal protein L19e
D Metho_0717 ribosomal protein L21E K02889 RP-L21e; large subunit ribosomal protein L21e
D Metho_1517 ribosomal protein L24E K02896 RP-L24e; large subunit ribosomal protein L24e
D Metho_1922 ribosomal protein L30E K02908 RP-L30e; large subunit ribosomal protein L30e
D Metho_0857 ribosomal protein L31E K02910 RP-L31e; large subunit ribosomal protein L31e
D Metho_2008 ribosomal protein L32E K02912 RP-L32e; large subunit ribosomal protein L32e
D Metho_0712 ribosomal protein L37E K02922 RP-L37e; large subunit ribosomal protein L37e
D Metho_1887 ribosomal protein L37a K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D Metho_0856 ribosomal protein L39E K02924 RP-L39e; large subunit ribosomal protein L39e
D Metho_0330 ribosomal protein L40E K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D Metho_0399 ribosomal protein L44E K02929 RP-L44e; large subunit ribosomal protein L44e
D Metho_1637 ribosomal protein Sa/S2 K02967 RP-S2; small subunit ribosomal protein S2
D Metho_2019 ribosomal protein S3, eukaryotic/archaeal type K02982 RP-S3; small subunit ribosomal protein S3
D Metho_1991 ribosomal protein S4/S9 K02986 RP-S4; small subunit ribosomal protein S4
D Metho_2005 ribosomal protein S5/S2 K02988 RP-S5; small subunit ribosomal protein S5
D Metho_1925 ribosomal protein S7/S5 K02992 RP-S7; small subunit ribosomal protein S7
D Metho_2010 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D Metho_1641 archaeal ribosomal protein S9P K02996 RP-S9; small subunit ribosomal protein S9
D Metho_1928 ribosomal protein S10/S20 K02946 RP-S10; small subunit ribosomal protein S10
D Metho_1990 archaeal ribosomal protein S11P K02948 RP-S11; small subunit ribosomal protein S11
D Metho_1924 ribosomal protein S23 K02950 RP-S12; small subunit ribosomal protein S12
D Metho_1992 archaeal ribosomal protein S13P K02952 RP-S13; small subunit ribosomal protein S13
D Metho_2011 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D Metho_1851 ribosomal protein S15P/S13E K02956 RP-S15; small subunit ribosomal protein S15
D Metho_2016 archaeal ribosomal protein S17P K02961 RP-S17; small subunit ribosomal protein S17
D Metho_2021 ribosomal protein S19/S15 K02965 RP-S19; small subunit ribosomal protein S19
D Metho_2348 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D Metho_2022 ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D Metho_2025 archaeal ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D Metho_2012 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D Metho_2009 archaeal ribosomal protein L6P K02933 RP-L6; large subunit ribosomal protein L6
D Metho_2347 ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D Metho_2349 ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D Metho_1642 ribosomal protein L13, archaeal/eukaryotic K02871 RP-L13; large subunit ribosomal protein L13
D Metho_2015 50S ribosomal protein L14P K02874 RP-L14; large subunit ribosomal protein L14
D Metho_2003 ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D Metho_2006 ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D Metho_2020 ribosomal protein L22/L17 K02890 RP-L22; large subunit ribosomal protein L22
D Metho_2023 archaeal ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D Metho_2014 ribosomal protein L24p/L26e, archaeal/eukaryotic K02895 RP-L24; large subunit ribosomal protein L24
D Metho_2018 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D Metho_2004 50S ribosomal protein L30P, archaeal K02907 RP-L30; large subunit ribosomal protein L30
D Metho_2346 50S ribosomal protein L12P K02869 RP-L12; large subunit ribosomal protein L12
D Metho_0859 ribosomal protein L20A (L18A) K02944 RP-LX; large subunit ribosomal protein LX
D Metho_0236 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Metho_2397 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Metho_0232 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Metho_2401 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Metho_2399 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Metho_0234 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:mhz03009]
D Metho_0054 rRNA biogenesis protein K14564 NOP56; nucleolar protein 56
D Metho_0396 putative Zn-ribbon RNA-binding protein K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D Metho_1889 putative exosome subunit/U3 small nucleolar ribonucleoprotein (snoRNP) component, contains IMP4 domain K14561 IMP4; U3 small nucleolar ribonucleoprotein protein IMP4
D Metho_0229 KH domain protein K06961 KRR1; ribosomal RNA assembly protein
D Metho_0230 serine/threonine protein kinase involved in cell cycle control K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D Metho_0800 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain protein K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D Metho_2181 putative nucleoside kinase, CMP and AMP kinase K18532 AK6; adenylate kinase [EC:2.7.4.3]
D Metho_1744 hypothetical protein K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157]
D Metho_2379 putative ATPase, Rnase L inhibitor (RLI) like protein K06174 ABCE1; ATP-binding cassette, sub-family E, member 1
D Metho_0197 putative GTPase K06943 NOG1; nucleolar GTP-binding protein
D Metho_2017 RNase P/RNase MRP subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D Metho_1881 RNase P/RNase MRP subunit POP5 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D Metho_1880 RNase P/RNase MRP subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D Metho_0858 translation initiation factor eIF-6, putative K03264 EIF6; translation initiation factor 6
D Metho_0987 NMD protein affecting ribosome stability and mRNA decay K07562 NMD3; 60S ribosomal export protein NMD3
D Metho_1883 rRNA metabolism protein, SBDS family K14574 SDO1; ribosome maturation protein SDO1
D Metho_0532 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Metho_2282 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Metho_0202 small GTP-binding protein domain protein K03595 era; GTPase
D Metho_0053 fibrillarin-like rRNA methylase K04795 flpA; fibrillarin-like pre-rRNA processing protein
D Metho_1515 50S ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D Metho_1279 RNA-binding protein involved in rRNA processing K07569 gar1; RNA-binding protein
D Metho_1923 NusA family KH domain protein K02600 nusA; transcription termination/antitermination protein NusA
D Metho_0720 dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D Metho_1701 putative rRNA methylase K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]
D Metho_0577 23S rRNA methylase K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D Metho_0105 ribosomal-protein-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D Metho_2411 ribosomal-protein-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D Metho_2170 acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D Metho_1306 DNA/RNA helicase, superfamily II K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D Metho_1178 DNA/RNA helicase, superfamily II K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D Metho_1307 ribosome small subunit-dependent GTPase A K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
D Metho_0748 GTP-binding protein HflX K03665 hflX; GTPase
D Metho_1661 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Metho_2221 putative RNA-binding protein containing KH domain, possibly ribosomal protein K07574 yhbY; RNA-binding protein
D Metho_0103 putative GTPase, probable translation factor K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:mhz03016]
D Metho_2017 RNase P/RNase MRP subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D Metho_1881 RNase P/RNase MRP subunit POP5 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D Metho_1880 RNase P/RNase MRP subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D Metho_0205 RNase P subunit RPR2 K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D Metho_0706 ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D Metho_0446 hypothetical protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D Metho_0445 hypothetical protein K24956 ZBTB8OS; protein archease
D Metho_1927 translation elongation factor EF-1 alpha K03231 EEF1A; elongation factor 1-alpha
D Metho_0813 glutamyl-tRNA synthetase, archaeal and eukaryotic family K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Metho_1872 prolyl-tRNA synthetase, family I K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Metho_1546 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Metho_0579 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Metho_2371 protein containing C-terminal region/beta chain of methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Metho_0040 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Metho_0470 alanine--tRNA ligase/alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Metho_0253 glycyl-tRNA synthetase, dimeric type K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Metho_0494 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Metho_1840 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Metho_0101 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Metho_1867 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Metho_1856 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Metho_2213 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Metho_1056 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Metho_2059 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Metho_2214 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D Metho_2353 hypothetical protein K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D Metho_1647 putative metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain protein K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
D Metho_1291 HIT family hydrolase, diadenosine tetraphosphate hydrolase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D Metho_0582 MiaB-like tRNA modifying enzyme K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
D Metho_1535 tRNA(guanine-26,N2-N2) methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D Metho_1276 putative methyltransferase K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D Metho_2107 tRNA(1-methyladenosine) methyltransferase-like methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D Metho_0437 hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D Metho_0038 wyosine biosynthesis protein TYW1 K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D Metho_1531 putative methyltransferase K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D Metho_0138 pseudouridylate synthase I K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D Metho_1998 rRNA pseudouridine synthase, putative K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D Metho_1423 tRNA pseudouridine synthase, TruD family K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D Metho_0716 TIGR01213 family protein K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D Metho_1173 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Metho_2275 cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Metho_0570 Kae1-associated kinase Bud32 K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D Metho_0569 metallohydrolase, glycoprotease/Kae1 family K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D Metho_2074 histone acetyltransferase, ELP3 family K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D Metho_1661 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Metho_2060 hypothetical protein K10761 THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79]
D Metho_0539 Archaeal RNase P K01978 rnpB; M1 RNA
D Metho_0337 RNA ligase partner, MJ_0950 family K09006 K09006; RNA-free ribonuclease P [EC:3.1.26.5]
D Metho_2030 CCA-adding enzyme K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
D Metho_0746 tRNA intron endonuclease K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D Metho_0408 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D Metho_2416 RNA:NAD 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
D Metho_0184 lysyl-tRNA synthetase, archaeal and spirochete K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D Metho_1011 aspartyl-tRNA synthetase, archaeal type K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D Metho_0022 pyrrolysyl-tRNA synthetase, C-terminal region/pyrrolysyl-tRNA synthetase, N-terminal region K11627 pylS; pyrrolysyl-tRNA synthetase [EC:6.1.1.26]
D Metho_0248 O-phosphoseryl-tRNA(Cys) synthetase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
D Metho_0600 Sep-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
D Metho_2240 Sep-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
D Metho_2437 putative TIM-barrel protein, nifR3 family K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D Metho_1581 methylase involved in ubiquinone/menaquinone biosynthesis K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D Metho_0715 hypothetical protein K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257]
D Metho_0141 putative DNA modification methylase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D Metho_1155 hypothetical protein K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
D Metho_1171 putative redox protein, regulator of disulfide bond formation K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D Metho_0580 hypothetical protein K09119 cgi121; KEOPS complex subunit Cgi121
D Metho_1890 hypothetical protein K09741 pcc1; KEOPS complex subunit Pcc1
D Metho_1836 queuosine biosynthesis protein QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D Metho_1833 queuosine biosynthesis protein QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D Metho_1834 organic radical activating enzyme K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D Metho_2280 putative Fe-S protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D Metho_0237 tRNA-guanine transglycosylase, archaeosine-15-forming K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D Metho_0496 thiazole biosynthesis/tRNA modification protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D Metho_2324 putative DNA-binding protein containing a Zn-ribbon domain K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
C 03012 Translation factors [BR:mhz03012]
D Metho_0231 eukaryotic/archaeal initiation factor 1A K03236 EIF1A; translation initiation factor 1A
D Metho_1304 eukaryotic/archaeal initiation factor 1A K03236 EIF1A; translation initiation factor 1A
D Metho_2276 translation initiation factor SUI1, putative, prokaryotic K03113 EIF1; translation initiation factor 1
D Metho_0397 translation initiation factor 2, alpha subunit (eIF-2alpha) K03237 EIF2S1; translation initiation factor 2 subunit 1
D Metho_2217 translation initiation factor aIF-2, beta subunit, putative K03238 EIF2S2; translation initiation factor 2 subunit 2
D Metho_0551 translation initiation factor 2 subunit gamma K03242 EIF2S3; translation initiation factor 2 subunit 3
D Metho_0169 translation initiation factor eIF-5A K03263 EIF5A; translation initiation factor 5A
D Metho_1519 translation initiation factor aIF-2/yIF-2 K03243 EIF5B; translation initiation factor 5B
D Metho_0858 translation initiation factor eIF-6, putative K03264 EIF6; translation initiation factor 6
D Metho_1927 translation elongation factor EF-1 alpha K03231 EEF1A; elongation factor 1-alpha
D Metho_0936 translation elongation factor aEF-1 beta K03232 EEF1B; elongation factor 1-beta
D Metho_1926 translation elongation factor aEF-2 K03234 EEF2; elongation factor 2
D Metho_2424 selenocysteine-specific translation elongation factor K03833 selB; selenocysteine-specific elongation factor
D Metho_2235 diphthamide biosynthesis enzyme Dph2 K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108]
D Metho_1047 metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14]
D Metho_0039 peptide chain release factor eRF/aRF, subunit 1 K03265 ETF1; peptide chain release factor subunit 1
D Metho_0721 HemK-related putative methylase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D Metho_1410 peptidyl-tRNA hydrolase K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]
C 03110 Chaperones and folding catalysts [BR:mhz03110]
D Metho_0737 ATP-dependent chaperone ClpB K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D Metho_0943 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D Metho_0739 chaperonin GroL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Metho_1261 chaperonin GroEL K22447 cct; archaeal chaperonin
D Metho_2168 thermosome subunit K22447 cct; archaeal chaperonin
D Metho_2307 thermosome subunit K22447 cct; archaeal chaperonin
D Metho_1699 chaperonin GroEL K22447 cct; archaeal chaperonin
D Metho_0944 chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D Metho_0942 molecular chaperone GrpE (heat shock protein) K03687 GRPE; molecular chaperone GrpE
D Metho_2632 hypothetical protein K13993 HSP20; HSP20 family protein
D Metho_0738 molecular chaperone (small heat shock protein) K13993 HSP20; HSP20 family protein
D Metho_2636 hypothetical protein K13993 HSP20; HSP20 family protein
D Metho_2080 molecular chaperone (small heat shock protein) K13993 HSP20; HSP20 family protein
D Metho_1067 molecular chaperone (small heat shock protein) K13993 HSP20; HSP20 family protein
D Metho_0740 Co-chaperonin GroES K04078 groES; chaperonin GroES
D Metho_0860 prefoldin alpha subunit/subunit 5 K04797 pfdA; prefoldin alpha subunit
D Metho_1891 prefoldin, beta subunit, archaeal K04798 pfdB; prefoldin beta subunit
D Metho_2263 subtilisin-like serine protease K01342 aprE; subtilisin [EC:3.4.21.62]
D Metho_0116 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D Metho_0961 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]
D Metho_1715 thioredoxin K03671 TXN; thioredoxin
D Metho_2382 thioredoxin domain-containing protein K03671 TXN; thioredoxin
D Metho_1904 thioredoxin domain-containing protein K03671 TXN; thioredoxin
D Metho_2196 thioredoxin domain-containing protein K03671 TXN; thioredoxin
D Metho_2109 glutaredoxin-like protein K03676 grxC; glutaredoxin 3
C 04131 Membrane trafficking [BR:mhz04131]
D Metho_1518 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D Metho_0532 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Metho_2282 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Metho_0537 putative membrane protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D Metho_2351 protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D Metho_1947 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D Metho_1927 translation elongation factor EF-1 alpha K03231 EEF1A; elongation factor 1-alpha
C 04121 Ubiquitin system [BR:mhz04121]
D Metho_0330 ribosomal protein L40E K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D Metho_0558 ribosomal protein S27AE K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C 03051 Proteasome [BR:mhz03051]
D Metho_1882 proteasome endopeptidase complex, archaeal, alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Metho_0991 proteasome endopeptidase complex, archaeal, beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D Metho_0620 26S proteasome subunit P45 family K03420 psmR; proteasome regulatory subunit
D Metho_2207 26S proteasome subunit P45 family K03420 psmR; proteasome regulatory subunit
C 03032 DNA replication proteins [BR:mhz03032]
D Metho_2417 single-stranded DNA-binding protein K07466 RFA1; replication factor A1
D Metho_0458 proliferating cell nuclear antigen PCNA K04802 PCNA; proliferating cell nuclear antigen
D Metho_0147 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Metho_1282 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Metho_1681 ATP-dependent DNA ligase I K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Metho_2701 DNA-methyltransferase Dcm K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D Metho_2718 site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D Metho_0396 putative Zn-ribbon RNA-binding protein K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D Metho_0682 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D Metho_2413 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D Metho_0001 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Metho_2727 Cdc6-related protein, AAA superfamily ATPase K10725 cdc6A; archaeal cell division control protein 6
D Metho_2483 Cdc6-related protein, AAA superfamily ATPase K10725 cdc6A; archaeal cell division control protein 6
D Metho_2169 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Metho_2462 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Metho_0796 putative ATPase involved in replication control, Cdc46/Mcm family K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D Metho_2482 putative ATPase involved in replication control, Cdc46/Mcm family K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D Metho_0403 DNA primase, eukaryotic-type, small subunit, putative K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D Metho_0459 DNA primase, large subunit K18882 priL; DNA primase large subunit
D Metho_0400 hypothetical protein K09723 ginS; DNA replication factor GINS
D Metho_1052 ribonuclease H, mammalian HI/archaeal HII subfamily K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Metho_2471 ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4]
D Metho_2679 DNA polymerase elongation subunit (family B) K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D Metho_0220 DNA polymerase elongation subunit (family B) K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D Metho_1664 DNA polymerase type II, large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D Metho_0003 archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D Metho_0659 DNA polymerase III, gamma/tau subunit K04800 rfcL; replication factor C large subunit
D Metho_0419 DNA polymerase III, gamma/tau subunit K04801 rfcS; replication factor C small subunit
D Metho_2075 DNA polymerase III, gamma/tau subunit K04801 rfcS; replication factor C small subunit
D Metho_1032 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D Metho_1031 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D Metho_0656 DNA topoisomerase VI, subunit A K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2]
D Metho_0657 DNA topoisomerase VI, B subunit K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
D Metho_0808 DNA topoisomerase I, archaeal K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D Metho_2508 topoisomerase IA K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D Metho_1787 topoisomerase IA K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:mhz03036]
D Metho_2701 DNA-methyltransferase Dcm K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D Metho_2718 site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D Metho_0421 histones H3 and H4 K24450 hmf; DNA-binding protein
D Metho_0069 chromosome segregation protein SMC K03529 smc; chromosome segregation protein
D Metho_0070 hypothetical protein K05896 scpA; segregation and condensation protein A
D Metho_2658 hypothetical protein K05896 scpA; segregation and condensation protein A
D Metho_0071 segregation and condensation protein B K06024 scpB; segregation and condensation protein B
D Metho_0995 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Metho_2352 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Metho_1745 cell division ATPase MinD, archaeal K03609 minD; septum site-determining protein MinD
D Metho_2697 ATPase involved in chromosome partitioning K03496 parA; chromosome partitioning protein
D Metho_1270 site-specific recombinase XerD K04763 xerD; integrase/recombinase XerD
D Metho_0672 site-specific recombinase XerD K04763 xerD; integrase/recombinase XerD
D Metho_2122 ATPase involved in chromosome partitioning K03593 mrp; ATP-binding protein involved in chromosome partitioning
D Metho_1995 hypothetical protein K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]
C 03400 DNA repair and recombination proteins [BR:mhz03400]
D Metho_0167 O-6-methylguanine DNA methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Metho_0627 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D Metho_2033 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D Metho_0260 putative endoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D Metho_2442 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D Metho_0458 proliferating cell nuclear antigen PCNA K04802 PCNA; proliferating cell nuclear antigen
D Metho_0147 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Metho_1282 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Metho_1681 ATP-dependent DNA ligase I K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Metho_0058 DNA helicase, Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D Metho_2417 single-stranded DNA-binding protein K07466 RFA1; replication factor A1
D Metho_0456 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Metho_0956 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Metho_0255 deoxycytidine deaminase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Metho_1827 deoxyribodipyrimidine photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D Metho_1844 uracil-DNA glycosylase, family 4 K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D Metho_1742 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D Metho_2288 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D Metho_1105 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_2670 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_1846 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_2068 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Metho_1950 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
D Metho_0624 excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
D Metho_2065 excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C
D Metho_2592 DNA/RNA helicase, superfamily I K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D Metho_2296 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Metho_0090 mismatch repair ATPase (MutS family) K07456 mutS2; DNA mismatch repair protein MutS2
D Metho_2295 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Metho_1977 exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D Metho_1976 exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D Metho_0067 ATPase involved in DNA repair K03546 sbcC; DNA repair protein SbcC/Rad50
D Metho_0066 DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
D Metho_0321 putative transcriptional regulator with HTH domain K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D Metho_1369 putative transcriptional regulator with HTH domain K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D Metho_2039 putative transcriptional regulator with HTH domain K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D Metho_1393 putative transcriptional regulator with HTH domain K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D Metho_1139 CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D Metho_2285 DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA
D Metho_2108 DNA repair and recombination protein RadB K04484 radB; DNA repair protein RadB
D Metho_2674 superfamily II helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
D Metho_2463 superfamily II helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
D Metho_1859 superfamily II helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
D Metho_1032 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D Metho_1031 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D Metho_0808 DNA topoisomerase I, archaeal K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D Metho_2508 topoisomerase IA K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D Metho_1787 topoisomerase IA K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D Metho_0286 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D Metho_0276 nucleotidyltransferase/DNA polymerase involved in DNA repair K04479 dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7]
D Metho_2455 nucleotidyltransferase/DNA polymerase involved in DNA repair K04479 dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7]
D Metho_1717 DNA polymerase IV (family X) K02347 polX; DNA polymerase (family X)
D Metho_0777 Lhr-like helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D Metho_2272 hypothetical protein K22585 nreA; DNA repair protein NreA
C 03029 Mitochondrial biogenesis [BR:mhz03029]
D Metho_2017 RNase P/RNase MRP subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D Metho_1881 RNase P/RNase MRP subunit POP5 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D Metho_1880 RNase P/RNase MRP subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D Metho_0202 small GTP-binding protein domain protein K03595 era; GTPase
D Metho_2059 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Metho_0579 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Metho_0253 glycyl-tRNA synthetase, dimeric type K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Metho_0040 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Metho_0332 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D Metho_0331 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D Metho_0333 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D Metho_0943 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D Metho_0942 molecular chaperone GrpE (heat shock protein) K03687 GRPE; molecular chaperone GrpE
D Metho_0739 chaperonin GroL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Metho_0740 Co-chaperonin GroES K04078 groES; chaperonin GroES
D Metho_0944 chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D Metho_1173 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Metho_2275 cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Metho_2122 ATPase involved in chromosome partitioning K03593 mrp; ATP-binding protein involved in chromosome partitioning
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:mhz02000]
D Metho_2316 molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 modA; molybdate transport system substrate-binding protein
D Metho_2315 molybdate ABC transporter, permease protein K02018 modB; molybdate transport system permease protein
D Metho_2314 ABC-type spermidine/putrescine transport system, ATPase component K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5]
D Metho_2116 ABC transporter, substrate-binding protein, aliphatic sulfonates family K15553 ssuA; sulfonate transport system substrate-binding protein
D Metho_2117 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component K15554 ssuC; sulfonate transport system permease protein
D Metho_2118 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D Metho_1123 periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) K05845 opuC; osmoprotectant transport system substrate-binding protein
D Metho_1120 ABC-type proline/glycine betaine transport system, permease component K05846 opuBD; osmoprotectant transport system permease protein
D Metho_1121 ABC-type proline/glycine betaine transport system, permease component K05846 opuBD; osmoprotectant transport system permease protein
D Metho_1122 glycine betaine/L-proline transport ATP binding subunit K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]
D Metho_2178 TIGR00245 family protein K02069 STAR2; UDP-glucose/iron transport system permease protein
D Metho_2179 ABC-type uncharacterized transport system, ATPase component K02068 STAR1; UDP-glucose/iron transport system ATP-binding protein
D Metho_0225 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein
D Metho_0224 phosphate ABC transporter, permease protein PstC K02037 pstC; phosphate transport system permease protein
D Metho_0223 phosphate ABC transporter, permease protein PstA K02038 pstA; phosphate transport system permease protein
D Metho_0222 phosphate ABC transporter, ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D Metho_1459 periplasmic component of amino acid ABC-type transporter/signal transduction system K10036 glnH; glutamine transport system substrate-binding protein
D Metho_1160 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family K10037 glnP; glutamine transport system permease protein
D Metho_1159 ABC-type polar amino acid transport system, ATPase component K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1]
D Metho_1567 ABC-type Fe3+-hydroxamate transport system, periplasmic component K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D Metho_1568 ABC-type Fe3+-siderophore transport system, permease component K02015 ABC.FEV.P; iron complex transport system permease protein
D Metho_0524 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D Metho_1569 ABC-type cobalamin/Fe3+-siderophore transport system, ATPase component K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D Metho_2136 ABC-type metal ion transport system, periplasmic component/surface adhesin K09815 znuA; zinc transport system substrate-binding protein
D Metho_2138 ABC-type Mn2+/Zn2+ transport system, permease component K09816 znuB; zinc transport system permease protein
D Metho_2137 ATPase component of Mn/Zn ABC-type transporter K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D Metho_0508 hypothetical protein K02009 cbiN; cobalt/nickel transport protein
D Metho_2291 ABC-type cobalt transport system, periplasmic component K02009 cbiN; cobalt/nickel transport protein
D Metho_0522 cobalt ABC transporter, permease protein CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein
D Metho_2290 cobalt ABC transporter, permease protein CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein
D Metho_0507 ABC-type Co2+ transport system, permease component K02007 cbiM; cobalt/nickel transport system permease protein
D Metho_2292 cobalamin biosynthesis protein CbiM K02007 cbiM; cobalt/nickel transport system permease protein
D Metho_0523 cobalt transport protein ATP-binding subunit K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D Metho_2289 cobalt transport protein ATP-binding subunit K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D Metho_2308 hypothetical protein K03523 bioY; biotin transport system substrate-specific component
D Metho_2311 ABC-type cobalt transport system, permease component CbiQ K16785 ecfT; energy-coupling factor transport system permease protein
D Metho_2309 ABC-type cobalt transport system, ATPase component K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D Metho_2310 ABC-type cobalt transport system, ATPase component K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D Metho_1285 ABC-type polysaccharide/polyol phosphate export systems, permease component K09690 wzm; homopolymeric O-antigen transport system permease protein
D Metho_1286 ABC-type polysaccharide/polyol phosphate transport system, ATPase component K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14]
D Metho_0110 ABC-type polysaccharide/polyol phosphate export systems, permease component K09694 nodJ; lipooligosaccharide transport system permease protein
D Metho_0111 ABC-type multidrug transport system, ATPase component K09695 nodI; lipooligosaccharide transport system ATP-binding protein
D Metho_1561 ABC-type transport system involved in cytochrome c biogenesis, permease component K02195 ccmC; heme exporter protein C
D Metho_1562 ABC-type transport system involved in cytochrome c biogenesis, permease component K02194 ccmB; heme exporter protein B
D Metho_1563 ABC-type multidrug transport system, ATPase component K02193 ccmA; heme exporter protein A [EC:7.6.2.5]
D Metho_1966 ABC-type multidrug transport system, permease component K01992 ABC-2.P; ABC-2 type transport system permease protein
D Metho_2303 ABC-type polysaccharide/polyol phosphate export systems, permease component K01992 ABC-2.P; ABC-2 type transport system permease protein
D Metho_0044 ABC-type Na+ efflux pump, permease component K01992 ABC-2.P; ABC-2 type transport system permease protein
D Metho_0042 ABC-type multidrug transport system, ATPase component K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Metho_2541 ABC-type multidrug transport system, ATPase component K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Metho_1967 ABC-type multidrug transport system, ATPase component K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Metho_2304 daunorubicin resistance ABC transporter ATP-binding subunit K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Metho_0128 ABC-type transport system, involved in lipoprotein release, permease component K02004 ABC.CD.P; putative ABC transport system permease protein
D Metho_0374 ABC-type transport system, involved in lipoprotein release, permease component K02004 ABC.CD.P; putative ABC transport system permease protein
D Metho_0381 ABC-type antimicrobial peptide transport system, permease component K02004 ABC.CD.P; putative ABC transport system permease protein
D Metho_0382 ABC-type transport system, involved in lipoprotein release, permease component K02004 ABC.CD.P; putative ABC transport system permease protein
D Metho_1814 ABC-type transport system, involved in lipoprotein release, permease component K02004 ABC.CD.P; putative ABC transport system permease protein
D Metho_1351 ABC-type transport system, involved in lipoprotein release, permease component K02004 ABC.CD.P; putative ABC transport system permease protein
D Metho_2563 ABC-type transport system, involved in lipoprotein release, permease component K02004 ABC.CD.P; putative ABC transport system permease protein
D Metho_0129 ABC-type antimicrobial peptide transport system, ATPase component K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D Metho_0375 ABC-type antimicrobial peptide transport system, ATPase component K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D Metho_0379 ABC-type antimicrobial peptide transport system, ATPase component K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D Metho_2562 ABC-type antimicrobial peptide transport system, ATPase component K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D Metho_1352 ABC-type antimicrobial peptide transport system, ATPase component K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D Metho_1813 ABC-type antimicrobial peptide transport system, ATPase component K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D Metho_1512 ABC-type transport system involved in Fe-S cluster assembly, ATPase component K09013 sufC; Fe-S cluster assembly ATP-binding protein
D Metho_0628 putative efflux protein, MATE family K26937 dinF; MATE family, multidrug efflux pump
D Metho_0083 putative efflux protein, MATE family K26937 dinF; MATE family, multidrug efflux pump
D Metho_1648 arabinose efflux permease family protein K08151 tetA; MFS transporter, DHA1 family, tetracycline resistance protein
D Metho_0986 MIP family channel protein K02440 glpF; glycerol uptake facilitator
D Metho_1066 ammonium transporter K03320 amt; ammonium transporter, Amt family
D Metho_1858 small-conductance mechanosensitive channel K03442 mscS; small conductance mechanosensitive channel
D Metho_1283 small-conductance mechanosensitive channel K22044 ybiO; moderate conductance mechanosensitive channel
D Metho_2241 small-conductance mechanosensitive channel K16052 ynaI; MscS family membrane protein
D Metho_1014 cation transporter K07244 K07244; mgtE-like transporter
D Metho_1015 cation transporter K07244 K07244; mgtE-like transporter
D Metho_0515 Mg2+/Co2+ transporter K03284 corA; magnesium transporter
D Metho_1020 Mg2+/Co2+ transporter K03284 corA; magnesium transporter
D Metho_0904 magnesium Mg(2+) and cobalt Co(2+) transport protein CorA K03284 corA; magnesium transporter
D Metho_2223 Integral membrane protein possibly involved in chromosome condensation K06199 crcB; fluoride exporter
D Metho_2224 Integral membrane protein possibly involved in chromosome condensation K06199 crcB; fluoride exporter
D Metho_0652 CBS domain-containing protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
D Metho_0529 putative effector of murein hydrolase LrgA K06518 cidA; holin-like protein
D Metho_0011 amino acid transporter K16238 eat; ethanolamine permease
D Metho_2139 cation/cationic drug transporter K03297 emrE; small multidrug resistance pump
D Metho_1331 cation/cationic drug transporter K11741 sugE; quaternary ammonium compound-resistance protein SugE
D Metho_1441 H+/gluconate symporter family protein K03299 TC.GNTP; gluconate:H+ symporter, GntP family
D Metho_0958 K+dependent Na+ exchanger related-protein K07301 yrbG; cation:H+ antiporter
D Metho_0893 K+dependent Na+ exchanger related-protein K07301 yrbG; cation:H+ antiporter
D Metho_0646 Na+/panthothenate symporter K14392 panF; sodium/pantothenate symporter
D Metho_2055 Kef-type K+ transport system, membrane component K26735 KEA4_5_6; K+:H+ antiporter
D Metho_0392 Kef-type K+ transport system, membrane component K26731 CHX; K+:H+ antiporter
D Metho_2064 Trk-type K+ transport system, membrane component K03498 trkH; trk/ktr system potassium uptake protein
D Metho_0946 Trk-type K+ transport system, membrane component K03498 trkH; trk/ktr system potassium uptake protein
D Metho_0945 K+ transport system, NAD-binding component K03499 trkA; trk/ktr system potassium uptake protein
D Metho_0583 chloride channel protein EriC K03281 clcA; chloride channel protein, CIC family
D Metho_2443 sulfate permease-like transporter, MFS superfamily K03321 TC.SULP; sulfate permease, SulP family
D Metho_0900 arsenical-resistance protein K03325 ACR3; arsenite transporter
D Metho_0902 arsenite efflux pump ACR3-like permease K03325 ACR3; arsenite transporter
D Metho_1653 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/multisubunit Na+/H+ antiporter, MnhA subunit K05565 mnhA; multicomponent Na+:H+ antiporter subunit A
D Metho_1654 multisubunit Na+/H+ antiporter, MnhB subunit K05566 mnhB; multicomponent Na+:H+ antiporter subunit B
D Metho_1655 multisubunit Na+/H+ antiporter, MnhC subunit K05567 mnhC; multicomponent Na+:H+ antiporter subunit C
D Metho_1656 formate hydrogenlyase subunit 3/multisubunit Na+/H+ antiporter, MnhD subunit K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D Metho_1657 multisubunit Na+/H+ antiporter, MnhE subunit K05569 mnhE; multicomponent Na+:H+ antiporter subunit E
D Metho_1658 multisubunit Na+/H+ antiporter, MnhF subunit K05570 mnhF; multicomponent Na+:H+ antiporter subunit F
D Metho_1659 monovalent cation/proton antiporter, MnhG/PhaG subunit K05571 mnhG; multicomponent Na+:H+ antiporter subunit G
D Metho_1184 membrane protein involved in the export of O-antigen and teichoic acid K16695 wzxC; lipopolysaccharide exporter
D Metho_1249 K+ transporter K03549 kup; KUP system potassium uptake protein
D Metho_1954 putative branched-chain amino acid permease (azaleucine resistance) K26605 azlC; branched chain amino acid efflux pump
D Metho_1953 putative branched-chain amino acid permease K26606 azlD; branched chain amino acid efflux pump
D Metho_1784 membrane protein, MarC family K05595 marC; multiple antibiotic resistance protein
D Metho_0537 putative membrane protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D Metho_1071 ABC-type uncharacterized transport system, permease component K08970 rcnA; nickel/cobalt transporter (NicO) family protein
D Metho_1769 hypothetical protein K15383 K15383; MtN3 and saliva related transmembrane protein
D Metho_0998 vacuolar-type H(+)-translocating pyrophosphatase K15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1]
D Metho_0896 hypothetical protein K06196 ccdA; cytochrome c-type biogenesis protein
D Metho_0768 Fe2+ transport system protein A K04758 feoA; ferrous iron transport protein A
D Metho_1381 Fe2+ transport system protein A K04758 feoA; ferrous iron transport protein A
D Metho_0769 ferrous iron transporter FeoB K04759 feoB; ferrous iron transport protein B
D Metho_1975 cytochrome c biogenesis factor K02198 ccmF; cytochrome c-type biogenesis protein CcmF
C 02044 Secretion system [BR:mhz02044]
D Metho_0866 archaeal flagellin-like protein K07325 flaB; archaeal flagellin FlaB
D Metho_0573 archaeal flagellin-like protein K07325 flaB; archaeal flagellin FlaB
D Metho_0867 archaeal flagellin-like protein K07325 flaB; archaeal flagellin FlaB
D Metho_0870 archaeal flagellin-like protein K07325 flaB; archaeal flagellin FlaB
D Metho_0871 archaeal flagellin-like protein K07325 flaB; archaeal flagellin FlaB
D Metho_0473 putative archaeal flagellar protein D/E K07327 flaD; archaeal flagellar protein FlaD
D Metho_0474 putative archaeal flagellar protein F K07329 flaF; archaeal flagellar protein FlaF
D Metho_0475 putative archaeal flagellar protein G K07330 flaG; archaeal flagellar protein FlaG
D Metho_0476 putative ATPase involved in flagella biogenesis K07331 flaH; archaeal flagellar protein FlaH
D Metho_0477 ATPase, type IV secretory pathway VirB11 component like protein K07332 flaI; archaeal flagellar protein FlaI
D Metho_2524 ATPase, type IV secretory pathway VirB11 component like protein K07332 flaI; archaeal flagellar protein FlaI
D Metho_1746 ATPase, type IV secretory pathway VirB11 component like protein K07332 flaI; archaeal flagellar protein FlaI
D Metho_0478 archaeal flagella assembly protein J K07333 flaJ; archaeal flagellar protein FlaJ
D Metho_1053 Flp pilus assembly protein TadC K07333 flaJ; archaeal flagellar protein FlaJ
D Metho_1747 archaeal flagella assembly protein J K07333 flaJ; archaeal flagellar protein FlaJ
D Metho_1748 Flp pilus assembly protein TadC K07333 flaJ; archaeal flagellar protein FlaJ
D Metho_0284 prepilin signal peptidase PulO-like peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D Metho_2078 deoxycytidylate deaminase K01493 comEB; dCMP deaminase [EC:3.5.4.12]
D Metho_0689 putative hydrolase (metallo-beta-lactamase superfamily) K02238 comEC; competence protein ComEC
D Metho_2152 putative hydrolase (metallo-beta-lactamase superfamily) K02238 comEC; competence protein ComEC
D Metho_2343 putative hydrolase (metallo-beta-lactamase superfamily) K02238 comEC; competence protein ComEC
D Metho_2076 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D Metho_2077 preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D Metho_2002 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D Metho_0271 signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D Metho_0861 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D Metho_2351 protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D Metho_2102 signal recognition particle 19 kDa protein K03105 SRP19; signal recognition particle subunit SRP19
C 02042 Bacterial toxins [BR:mhz02042]
D Metho_0652 CBS domain-containing protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
C 02022 Two-component system [BR:mhz02022]
D Metho_1007 PAS domain S-box K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D Metho_1431 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D Metho_1429 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Metho_1430 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C 02035 Bacterial motility proteins [BR:mhz02035]
D Metho_1431 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D Metho_1021 chemotaxis signal transduction protein K03408 cheW; purine-binding chemotaxis protein CheW
D Metho_1432 chemotaxis protein CheC, inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC
D Metho_1434 chemotaxis protein CheC, inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC
D Metho_1437 chemotaxis protein CheC, inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC
D Metho_1435 chemotaxis protein K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]
D Metho_1433 methylase of chemotaxis methyl-accepting protein K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D Metho_1430 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D Metho_1429 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Metho_0962 methyl-accepting chemotaxis protein K03406 mcp; methyl-accepting chemotaxis protein
D Metho_0866 archaeal flagellin-like protein K07325 flaB; archaeal flagellin FlaB
D Metho_0573 archaeal flagellin-like protein K07325 flaB; archaeal flagellin FlaB
D Metho_0867 archaeal flagellin-like protein K07325 flaB; archaeal flagellin FlaB
D Metho_0870 archaeal flagellin-like protein K07325 flaB; archaeal flagellin FlaB
D Metho_0871 archaeal flagellin-like protein K07325 flaB; archaeal flagellin FlaB
D Metho_0473 putative archaeal flagellar protein D/E K07327 flaD; archaeal flagellar protein FlaD
D Metho_0474 putative archaeal flagellar protein F K07329 flaF; archaeal flagellar protein FlaF
D Metho_0475 putative archaeal flagellar protein G K07330 flaG; archaeal flagellar protein FlaG
D Metho_0476 putative ATPase involved in flagella biogenesis K07331 flaH; archaeal flagellar protein FlaH
D Metho_0477 ATPase, type IV secretory pathway VirB11 component like protein K07332 flaI; archaeal flagellar protein FlaI
D Metho_2524 ATPase, type IV secretory pathway VirB11 component like protein K07332 flaI; archaeal flagellar protein FlaI
D Metho_1746 ATPase, type IV secretory pathway VirB11 component like protein K07332 flaI; archaeal flagellar protein FlaI
D Metho_0478 archaeal flagella assembly protein J K07333 flaJ; archaeal flagellar protein FlaJ
D Metho_1053 Flp pilus assembly protein TadC K07333 flaJ; archaeal flagellar protein FlaJ
D Metho_1747 archaeal flagella assembly protein J K07333 flaJ; archaeal flagellar protein FlaJ
D Metho_1748 Flp pilus assembly protein TadC K07333 flaJ; archaeal flagellar protein FlaJ
D Metho_0284 prepilin signal peptidase PulO-like peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:mhz04812]
D Metho_1636 putative dioxygenase K06990 MEMO1; MEMO1 family protein
D Metho_0995 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Metho_2352 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Metho_1745 cell division ATPase MinD, archaeal K03609 minD; septum site-determining protein MinD
D Metho_2697 ATPase involved in chromosome partitioning K03496 parA; chromosome partitioning protein
C 04147 Exosome [BR:mhz04147]
D Metho_0369 phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Metho_0588 3-phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D Metho_1947 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D Metho_1871 peroxiredoxin K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D Metho_1740 peroxiredoxin K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D Metho_1927 translation elongation factor EF-1 alpha K03231 EEF1A; elongation factor 1-alpha
D Metho_1926 translation elongation factor aEF-2 K03234 EEF2; elongation factor 2
D Metho_0739 chaperonin GroL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Metho_0943 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D Metho_0147 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Metho_1282 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Metho_0558 ribosomal protein S27AE K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D Metho_1783 P-type ATPase, translocating K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
D Metho_0532 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Metho_2282 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Metho_1291 HIT family hydrolase, diadenosine tetraphosphate hydrolase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D Metho_2374 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Metho_2001 adenylate kinase family protein K00939 adk; adenylate kinase [EC:2.7.4.3]
D Metho_2234 PRPP-binding protein, adenine/guanine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D Metho_1009 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D Metho_1085 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D Metho_0301 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Metho_0307 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Metho_0823 delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D Metho_1646 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D Metho_0143 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D Metho_0754 glutamate dehydrogenase/leucine dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D Metho_0262 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 02048 Prokaryotic defense system [BR:mhz02048]
D Metho_1139 CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D Metho_1140 CRISPR-associated endoribonuclease Cas2 K09951 cas2; CRISPR-associated protein Cas2
D Metho_2595 CRISPR locus-related DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3
D Metho_1141 CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D Metho_2377 hypothetical protein K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D Metho_1145 CRISPR type III-B/RAMP module RAMP protein Cmr1 K07061 cmr1; CRISPR-associated protein Cmr1
D Metho_1146 uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) K19076 cmr2; CRISPR-associated protein Cmr2
D Metho_1148 CRISPR type III-B/RAMP module RAMP protein Cmr4 K09000 cmr4; CRISPR-associated protein Cmr4
D Metho_0322 helicase, type I site-specific restriction-modification system restriction subunit K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D Metho_0639 helicase, type I site-specific restriction-modification system restriction subunit K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D Metho_1322 type I site-specific deoxyribonuclease, HsdR family K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D Metho_1370 type I site-specific deoxyribonuclease, HsdR family K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D Metho_0320 restriction endonuclease S subunit K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D Metho_0636 restriction endonuclease S subunit K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D Metho_1317 restriction endonuclease S subunit K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D Metho_1368 restriction endonuclease S subunit K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D Metho_0317 type I restriction-modification system methyltransferase subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D Metho_0633 type I restriction-modification system methyltransferase subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D Metho_1314 type I restriction-modification system methyltransferase subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D Metho_1367 type I restriction system adenine methylase HsdM K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D Metho_0323 DNA modification methylase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]
D Metho_2708 DNA modification methylase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]
D Metho_2701 DNA-methyltransferase Dcm K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D Metho_2718 site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D Metho_2584 restriction endonuclease K01156 res; type III restriction enzyme [EC:3.1.21.5]
D Metho_2583 adenine specific DNA methylase Mod K07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72]
D Metho_1469 cytotoxic translational repressor of toxin-antitoxin stability system K06218 relE; mRNA interferase RelE/StbE
D Metho_0864 putative stress-responsive transcriptional regulator K03973 pspC; phage shock protein C
D Metho_1257 death-on-curing family protein K07341 doc; death on curing protein
D Metho_0995 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Metho_2352 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Metho_0813 glutamyl-tRNA synthetase, archaeal and eukaryotic family K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Metho_2326 putative nucleic acid-binding protein with PIN domain and Zn ribbon K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-]
D Metho_1173 cysteine desulfurase family protein K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Metho_2275 cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels [BR:mhz04040]
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes [BR:mhz01504]
D Metho_1648 arabinose efflux permease family protein K08151 tetA; MFS transporter, DHA1 family, tetracycline resistance protein
D Metho_1342 erythromycin esterase-like enzyme K06880 ereA_B; erythromycin esterase [EC:3.1.1.-]
D Metho_0521 hypothetical protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
D Metho_1905 hypothetical protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:mhz03100]
D Metho_0233 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Metho_2400 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Metho_0935 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Metho_0691 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Metho_0102 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Metho_0297 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Metho_1755 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Metho_1930 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Metho_2302 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Metho_1181 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D Metho_0096 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D Metho_0235 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D Metho_0608 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D Metho_2398 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D Metho_0601 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D Metho_1165 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Metho_2338 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Metho_2722 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Metho_1557 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Metho_0619 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Metho_1690 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Metho_0625 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Metho_2242 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Metho_0710 tRNA-His K14226 tRNA-His; tRNA His
D Metho_0692 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D Metho_0629 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Metho_1313 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Metho_1751 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Metho_1969 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Metho_1988 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Metho_2432 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Metho_1916 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Metho_0219 tRNA-Met K14230 tRNA-Met; tRNA Met
D Metho_0273 tRNA-Met K14230 tRNA-Met; tRNA Met
D Metho_1180 tRNA-Met K14230 tRNA-Met; tRNA Met
D Metho_1689 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D Metho_0113 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Metho_2229 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Metho_1639 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Metho_0207 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Metho_1997 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Metho_0960 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Metho_1824 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Metho_0442 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Metho_1271 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Metho_1273 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Metho_1874 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D Metho_0095 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D Metho_1688 tRNA-Val K14237 tRNA-Val; tRNA Val
D Metho_0257 tRNA-Val K14237 tRNA-Val; tRNA Val
D Metho_1016 tRNA-Val K14237 tRNA-Val; tRNA Val
D Metho_0232 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Metho_2401 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Metho_2399 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Metho_0234 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Metho_0236 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Metho_2397 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Metho_0208 Eukaryotic type signal recognition particle RNA K01983 ffs; SRP RNA
D Metho_0539 Archaeal RNase P K01978 rnpB; M1 RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D Metho_1797 putative dehydrogenase K18855 E1.1.1.374; UDP-N-acetylglucosamine 3-dehydrogenase [EC:1.1.1.374]
D Metho_0745 indolepyruvate ferredoxin oxidreductase, alpha/beta subunit K00179 iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8]
D Metho_2027 indolepyruvate ferredoxin oxidoreductase, alpha subunit K00179 iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8]
D Metho_2026 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 iorB; indolepyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.8]
D Metho_0755 NADPH-dependent F420 reductase K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40]
D Metho_2246 coenzyme F420-reducing hydrogenase, beta subunit K22162 fpoF; F420H2 dehydrogenase subunit F [EC:1.5.7.2 1.5.98.3]
D Metho_1454 NADH:ubiquinone oxidoreductase subunit 3 (chain A) K22158 fpoA; F420H2 dehydrogenase subunit A [EC:1.5.98.3]
D Metho_1453 NADH-quinone oxidoreductase, B subunit K22159 fpoB; F420H2 dehydrogenase subunit B [EC:1.5.98.3]
D Metho_1452 NADH/F420H2 dehydrogenase, subunit C K22160 fpoC; F420H2 dehydrogenase subunit C [EC:1.5.98.3]
D Metho_1451 NADH:ubiquinone oxidoreductase 49 kD subunit 7 K22161 fpoD; F420H2 dehydrogenase subunit D [EC:1.5.98.3]
D Metho_1450 NADH:ubiquinone oxidoreductase subunit 1 (chain H) K22163 fpoH; F420H2 dehydrogenase subunit H [EC:1.5.98.3]
D Metho_1449 NADH:ubiquinone oxidoreductase chain I-like protein K22164 fpoI; F420H2 dehydrogenase subunit I [EC:1.5.98.3]
D Metho_1447 NADH:ubiquinone oxidoreductase subunit 6 (chain J) K22165 fpoJ; F420H2 dehydrogenase subunit J [EC:1.5.98.3]
D Metho_1448 NADH:ubiquinone oxidoreductase subunit 6 (chain J) K22165 fpoJ; F420H2 dehydrogenase subunit J [EC:1.5.98.3]
D Metho_1446 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) K22166 fpoK; F420H2 dehydrogenase subunit K [EC:1.5.98.3]
D Metho_1445 proton-translocating NADH-quinone oxidoreductase, chain L K22167 fpoL; F420H2 dehydrogenase subunit L [EC:1.5.98.3]
D Metho_1444 proton-translocating NADH-quinone oxidoreductase, chain M K22168 fpoM; F420H2 dehydrogenase subunit M [EC:1.5.98.3]
D Metho_1443 proton-translocating NADH-quinone oxidoreductase, chain N K22169 fpoN; F420H2 dehydrogenase subunit N [EC:1.5.98.3]
D Metho_1442 F420H2 dehydrogenase subunit FpoO K22170 fpoO; F420H2 dehydrogenase subunit O [EC:1.5.98.3]
D Metho_2414 NAD(FAD)-dependent dehydrogenase K17870 nox1; NADH oxidase (H2O2-forming) [EC:1.6.3.3]
D Metho_2396 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component K17883 mtr; mycothione reductase [EC:1.8.1.15]
D Metho_0525 peptide methionine sulfoxide reductase K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D Metho_0352 peptide methionine sulfoxide reductase K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D Metho_1946 methionine-S-sulfoxide reductase K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D Metho_0079 methionine-R-sulfoxide reductase K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]
D Metho_1811 ferredoxin-thioredoxin reductase, catalytic subunit K17892 FTRC; ferredoxin-thioredoxin reductase catalytic chain [EC:1.8.7.2]
D Metho_0843 Peroxiredoxin K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D Metho_1907 Pirin-related protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]
D Metho_0008 Desulfoferrodoxin K05919 dfx; superoxide reductase [EC:1.15.1.2]
D Metho_1865 desulfoferrodoxin ferrous iron-binding domain protein K05919 dfx; superoxide reductase [EC:1.15.1.2]
D Metho_0004 putative metal-binding protein K16183 ramA; [Co(II) methylated amine-specific corrinoid protein] reductase [EC:1.16.99.1]
D Metho_0490 2-polyprenylphenol hydroxylase-like oxidoreductase K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]
D Metho_1693 protein-tyrosine-phosphatase K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D Metho_0362 putative Fe-S oxidoreductase K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5]
D Metho_1828 pyruvate-formate lyase-activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D Metho_2111 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D Metho_1182 pyruvate-formate lyase-activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D Metho_0172 protein-L-isoaspartate and D-aspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D Metho_1698 diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98]
D Metho_1665 putative methanogenesis marker protein 10 K25222 mmp10; [methyl coenzyme M reductase]-L-arginine C-5-methyltransferase [EC:2.1.1.379]
D Metho_0295 acetyltransferase K03828 yjgM; putative acetyltransferase [EC:2.3.1.-]
D Metho_0779 deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]
D Metho_1762 cysteate synthase K15527 K15527; cysteate synthase [EC:2.5.1.76]
D Metho_1245 NCAIR mutase-like protein K06898 larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143]
D Metho_2410 tRNA-guanine transglycosylase K07557 tgtA2; archaeosine synthase alpha-subunit [EC:2.6.1.97 2.6.1.-]
D Metho_0288 TIGR01210 family protein K06936 raSEA; archaeosine synthase beta-subunit [EC:2.6.1.-]
D Metho_0409 membrane-associated lipoprotein involved in thiamine biosynthesis K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180]
D Metho_0786 polyphosphate:AMP phosphotransferase K23753 ppk2; AMP-polyphosphate phosphotransferase [EC:2.7.4.33]
D Metho_2621 Retron-type reverse transcriptase K00986 ltrA; RNA-directed DNA polymerase [EC:2.7.7.49]
D Metho_1143 Retron-type reverse transcriptase K00986 ltrA; RNA-directed DNA polymerase [EC:2.7.7.49]
D Metho_0407 hypothetical protein K18672 dacA; diadenylate cyclase [EC:2.7.7.85]
D Metho_1049 phosphatidylglycerophosphate synthase K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39]
D Metho_0444 phosphatidylglycerophosphate synthase K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39]
D Metho_1040 putative phosphatase, C-terminal domain of histone macro H2A1 like protein K23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106]
D Metho_1901 putative thioesterase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D Metho_0439 putative metal-dependent phosphoesterase, PHP family K07053 E3.1.3.97; 3',5'-nucleoside bisphosphate phosphatase [EC:3.1.3.97]
D Metho_0891 hypothetical protein K09116 K09116; damage-control phosphatase, subfamily I [EC:3.1.3.-]
D Metho_2403 hydrolase, TatD family K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D Metho_0181 Nucleoside 2-deoxyribosyltransferase K22928 DNPH1; 2'-deoxynucleoside 5'-phosphate N-hydrolase [EC:3.2.2.-]
D Metho_0511 putative xylanase/chitin deacetylase K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]
D Metho_1129 MoxR-like ATPase K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D Metho_2344 hypothetical protein K22205 E3.13.2.3; S-adenosyl-L-methionine hydrolase (adenosine-forming) [EC:3.13.2.3]
D Metho_0191 yjeF-like protein, hydroxyethylthiazole kinase-related protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D Metho_2210 TIGR00268 family protein K06864 larE; pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase [EC:4.4.1.37]
D Metho_1246 TIGR00299 family protein K09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12]
D Metho_2173 putative methanogenesis marker protein 1 K24409 ycaO; thioglycine synthase [EC:6.2.2.1]
D Metho_2415 RNA 3''-phosphate cyclase K01974 RTCA; RNA 3'-terminal phosphate cyclase (ATP) [EC:6.5.1.4]
D Metho_2423 ATP-dependent DNA ligase K07468 K07468; DNA/RNA ligase [EC:6.5.1.-]
D Metho_0413 putative NADH:ubiquinone oxidoreductase, subunit RnfD K03614 rnfD; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit D [EC:7.1.1.11 7.2.1.2]
D Metho_0412 putative NADH:ubiquinone oxidoreductase, subunit RnfC K03615 rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2]
D Metho_0417 electron transport complex, RnfABCDGE type, B subunit K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2]
D Metho_1252 copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D Metho_2262 P-type ATPase, translocating K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10]
D Metho_0614 copper/silver-translocating P-type ATPase,heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]
D Metho_0514 magnesium-translocating P-type ATPase K01531 mgtA; P-type Mg2+ transporter [EC:7.2.2.14]
D Metho_1362 P-type ATPase, translocating K01531 mgtA; P-type Mg2+ transporter [EC:7.2.2.14]
C 99981 Carbohydrate metabolism
D Metho_1756 sugar fermentation stimulation protein K06206 sfsA; sugar fermentation stimulation protein A
C 99982 Energy metabolism
D Metho_0609 formate dehydrogenase family accessory protein FdhD K02379 fdhD; FdhD protein
D Metho_0733 formate dehydrogenase family accessory protein FdhD K02379 fdhD; FdhD protein
D Metho_1574 ferredoxin K05337 fer; ferredoxin
D Metho_0630 hypothetical protein K05524 fdxA; ferredoxin
D Metho_0414 electron transport complex, RnfABCDGE type, G subunit K03612 rnfG; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit G
D Metho_0415 electron transport complex, RnfABCDGE type, E subunit K03613 rnfE; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit E
D Metho_0416 electron transport complex, RnfABCDGE type, A subunit K03617 rnfA; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit A
D Metho_2274 iron-sulfur cluster biosynthesis protein, NifU-like protein K04488 iscU; nitrogen fixation protein NifU and related proteins
D Metho_1174 iron-sulfur cluster biosynthesis protein, NifU-like protein K04488 iscU; nitrogen fixation protein NifU and related proteins
D Metho_1767 nitric oxide reductase activation protein K02448 norD; nitric oxide reductase NorD protein
D Metho_0344 nitric oxide reductase activation protein K02448 norD; nitric oxide reductase NorD protein
D Metho_1766 ATPase family protein associated with various cellular activities (AAA) K04748 norQ; nitric oxide reductase NorQ protein
D Metho_1832 nitrogenase cofactor biosynthesis protein NifB K02585 nifB; nitrogen fixation protein NifB
D Metho_1118 hypothetical protein K02574 napH; ferredoxin-type protein NapH
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
D Metho_1344 pyridoxal phosphate enzyme, YggS family K06997 yggS; PLP dependent protein
C 99986 Glycan metabolism
D Metho_0510 hypothetical protein K07027 K07027; glycosyltransferase 2 family protein
D Metho_0513 hypothetical protein K07027 K07027; glycosyltransferase 2 family protein
D Metho_0666 hypothetical protein K07027 K07027; glycosyltransferase 2 family protein
D Metho_1293 hypothetical protein K07027 K07027; glycosyltransferase 2 family protein
C 99987 Cofactor metabolism
D Metho_1300 putative unusual protein kinase K03688 ubiB; ubiquinone biosynthesis protein
C 99988 Secondary metabolism
C 99999 Others
D Metho_2174 hypothetical protein K24410 tfuA; TfuA protein
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D Metho_2206 TIGR00270 family protein K03627 MBF1; putative transcription factor
D Metho_0713 small nuclear ribonucleoprotein K04796 RUXX; small nuclear ribonucleoprotein
D Metho_2067 hypothetical protein K21640 nrpRII; global nitrogen regulator NrpRII
D Metho_0196 putative transcriptional regulator, contains C-terminal CBS domains K07744 K07744; transcriptional regulator
C 99974 Translation
D Metho_0719 putative RNA-binding protein K07572 K07572; putative nucleotide binding protein
D Metho_0807 putative exonuclease of the beta-lactamase fold involved in RNA processing K07577 K07577; putative mRNA 3-end processing factor
D Metho_2381 putative exonuclease of the beta-lactamase fold involved in RNA processing K07577 K07577; putative mRNA 3-end processing factor
D Metho_2236 putative RNA methylase K07579 K07579; putative methylase
D Metho_0937 putative Zn-ribbon RNA-binding protein with a function in translation K07580 K07580; Zn-ribbon RNA-binding protein
D Metho_1879 putative exosome subunit K07581 K07581; RNA-binding protein
D Metho_0855 putative subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain K07585 K07585; tRNA methyltransferase
C 99975 Protein processing
D Metho_2331 hydrogenase maturation factor K07388 K07388; hydrogenase expression/formation protein
D Metho_0708 putative ATPase (AAA+ superfamily) K07392 PRS2; AAA family ATPase
D Metho_0447 prefoldin alpha subunit K07398 K07398; conserved protein with predicted RNA binding PUA domain
D Metho_2330 membrane-bound serine protease (ClpP class) K07403 nfeD; membrane-bound serine protease (ClpP class)
C 99976 Replication and repair
D Metho_0743 DNA repair protein radc K03630 radC; DNA repair protein RadC
D Metho_0187 putative endonuclease III-like protein K07457 K07457; endonuclease III related protein
D Metho_2616 hypothetical protein K07459 ybjD; putative ATP-dependent endonuclease of the OLD family
D Metho_0249 putative RNA-binding protein of the translin family K07477 K07477; translin
D Metho_0683 phage/plasmid primase, P4 family, C-terminal domain protein K06919 K06919; putative DNA primase/helicase
D Metho_2574 transposase, IS1 family K07480 insB; insertion element IS1 protein InsB
D Metho_2560 transposase, IS1 family K07480 insB; insertion element IS1 protein InsB
D Metho_2608 transposase, IS5 family K07481 K07481; transposase, IS5 family
D Metho_2631 transposase family protein K07485 K07485; transposase
D Metho_0971 transposase family protein K07485 K07485; transposase
D Metho_1477 transposase family protein K07485 K07485; transposase
D Metho_2526 transposase K07491 rayT; REP-associated tyrosine transposase
D Metho_2604 transposase K07491 rayT; REP-associated tyrosine transposase
D Metho_0534 transposase K07491 rayT; REP-associated tyrosine transposase
D Metho_1152 transposase K07493 K07493; putative transposase
D Metho_2086 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_2366 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_2527 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_0533 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_0702 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_1738 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_1460 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_2477 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_2535 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_2605 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_2688 transposase K07496 K07496; putative transposase
D Metho_2475 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_0060 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_2633 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_2668 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_1458 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_1468 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
D Metho_1487 transposase, IS605 OrfB family, central region K07496 K07496; putative transposase
C 99979 Viral proteins
C 99998 Others
D Metho_0460 phage shock protein A (IM30), suppresses sigma54-dependent transcription K03969 pspA; phage shock protein A
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D Metho_2271 phosphate/sulfate permease K03306 TC.PIT; inorganic phosphate transporter, PiT family
D Metho_0964 SSS sodium solute transporter K03307 TC.SSS; solute:Na+ symporter, SSS family
D Metho_0966 SSS sodium solute transporter K03307 TC.SSS; solute:Na+ symporter, SSS family
D Metho_2429 Na+/proline symporter K03307 TC.SSS; solute:Na+ symporter, SSS family
D Metho_1702 putative Na+-dependent transporter K03453 TC.BASS; bile acid:Na+ symporter, BASS family
C 99978 Cell growth
D Metho_1002 CO dehydrogenase maturation factor K07321 cooC; CO dehydrogenase maturation factor
D Metho_0978 CO dehydrogenase maturation factor K07321 cooC; CO dehydrogenase maturation factor
D Metho_0549 putative membrane protein K06384 spoIIM; stage II sporulation protein M
D Metho_2555 uncharacterized membrane protein K06384 spoIIM; stage II sporulation protein M
C 99993 Cell motility
D Metho_0502 archaeal flagellin-like protein K23255 pilA; archaeal type IV pilus assembly protein PilA
D Metho_0059 archaeal flagellin-like protein K23255 pilA; archaeal type IV pilus assembly protein PilA
C 99995 Signaling proteins
D Metho_0504 ACT domain-containing protein K07166 K07166; ACT domain-containing protein
D Metho_0269 RecA-superfamily ATPase possibly involved in signal transduction K08482 kaiC; circadian clock protein KaiC
D Metho_0227 RecA-superfamily ATPase possibly involved in signal transduction K08482 kaiC; circadian clock protein KaiC
D Metho_0880 RecA-superfamily ATPase possibly involved in signal transduction K08482 kaiC; circadian clock protein KaiC
D Metho_0854 DNA-binding protein K06875 PDCD5; programmed cell death protein 5
C 99992 Structural proteins
D Metho_0830 cytochrome c-type biogenesis protein CcmE K02197 ccmE; cytochrome c-type biogenesis protein CcmE
C 99994 Others
D Metho_0221 phosphate transport system regulatory protein PhoU K02039 phoU; phosphate transport system protein
D Metho_0655 uncharacterized protein involved in tolerance to divalent cations K03926 cutA; periplasmic divalent cation tolerance protein
D Metho_2298 molybdenum cofactor synthesis domain protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
B
B 09194 Poorly characterized
C 99996 General function prediction only
D Metho_2391 ATPase (PilT family) K06865 K06865; ATPase
D Metho_1906 helicase family protein with metal-binding cysteine cluster K06877 K06877; DEAD/DEAH box helicase domain-containing protein
D Metho_1932 haloacid dehalogenase superfamily enzyme, subfamily IA K07025 K07025; putative hydrolase of the HAD superfamily
D Metho_1523 haloacid dehalogenase superfamily enzyme, subfamily IA K07025 K07025; putative hydrolase of the HAD superfamily
D Metho_2387 Iron-sulfur cluster assembly accessory protein K15724 erpA; iron-sulfur cluster insertion protein
D Metho_1513 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 sufB; Fe-S cluster assembly protein SufB
D Metho_1806 putative membrane-bound metal-dependent hydrolase K07038 K07038; inner membrane protein
D Metho_1938 putative metal-dependent hydrolase (urease superfamily) K07049 K07049; TatD-related deoxyribonuclease
D Metho_1373 putative membrane protein K07058 K07058; membrane protein
D Metho_0251 putative Zn-finger containing protein K07143 K07143; UPF0148 protein
D Metho_1343 hypothetical protein K04750 phnB; PhnB protein
D Metho_2141 hypothetical protein K03744 lemA; LemA protein
D Metho_1001 putative membrane protein K08971 K08971; putative membrane protein
D Metho_1548 putative membrane protein K08975 K08975; putative membrane protein
C 99997 Function unknown
D Metho_0246 TIGR00161 family protein K06869 K06869; uncharacterized protein
D Metho_0586 protein with phosphotransacetylase BioD-like N-terminal domain K06873 K06873; uncharacterized protein
D Metho_2232 HD superfamily phosphohydrolase K06885 K06885; uncharacterized protein
D Metho_2106 HD superfamily phosphohydrolase K06885 K06885; uncharacterized protein
D Metho_1382 thioredoxin domain protein K06888 K06888; uncharacterized protein
D Metho_1931 dienelactone hydrolase-like enzyme K06889 K06889; uncharacterized protein
D Metho_1615 phage baseplate assembly protein W K06903 W; Bacteriophage baseplate protein W
D Metho_1618 phage protein D K06905 D; Bacteriophage probable baseplate hub protein
D Metho_1625 phage tail sheath protein FI K06907 FI; Bacteriophage tail sheath protein
D Metho_0988 putative ATP-dependent carboligase K06913 K06913; uncharacterized protein
D Metho_0592 putative ATPase (AAA+ superfamily) K06921 K06921; uncharacterized protein
D Metho_1386 putative ATPase K06926 K06926; uncharacterized protein
D Metho_2123 putative DNA-binding protein K06933 K06933; uncharacterized protein
D Metho_1759 putative Fe-S protein K06939 K06939; uncharacterized protein
D Metho_0193 Uncharacterized protein family (UPF0153) K06940 K06940; uncharacterized protein
D Metho_2166 putative Fe-S oxidoreductase K06940 K06940; uncharacterized protein
D Metho_2177 putative Fe-S oxidoreductase K06940 K06940; uncharacterized protein
D Metho_0990 TIGR00295 family protein K06950 K06950; uncharacterized protein
D Metho_1913 putative domain HDIG-containing protein K06950 K06950; uncharacterized protein
D Metho_0778 putative phosphoesterase, ICC K06953 K06953; uncharacterized protein
D Metho_1185 lactoylglutathione lyase family protein K06996 K06996; uncharacterized protein
D Metho_1039 hydrophobe/amphiphile efflux-3 family protein K07003 K07003; uncharacterized protein
D Metho_2155 hydrophobe/amphiphile efflux-3 family protein K07003 K07003; uncharacterized protein
D Metho_1035 pyridoxamine 5'-phosphate oxidase-related, FMN binding protein K07006 K07006; uncharacterized protein
D Metho_1829 pyridoxamine 5'-phosphate oxidase-related, FMN binding protein K07006 K07006; uncharacterized protein
D Metho_1532 putative hydrocarbon binding protein (contains V4R domain) K07013 K07013; uncharacterized protein
D Metho_1093 V4R domain-containing protein K07013 K07013; uncharacterized protein
D Metho_0406 putative membrane protein K07034 K07034; uncharacterized protein
D Metho_0992 KH-domain/beta-lactamase-domain protein K07041 K07041; uncharacterized protein
D Metho_2373 putative nucleic-acid-binding protein containing a Zn-ribbon K07068 K07068; uncharacterized protein
D Metho_1058 putative nucleotidyltransferase K07075 K07075; uncharacterized protein
D Metho_2445 putative oxidoreductase of aldo/keto reductase family K07079 K07079; uncharacterized protein
D Metho_0908 putative permease K07089 K07089; uncharacterized protein
D Metho_0916 putative permease K07089 K07089; uncharacterized protein
D Metho_0903 putative permease K07090 K07090; uncharacterized protein
D Metho_1754 putative permease K07090 K07090; uncharacterized protein
D Metho_0432 phosphoesterase, MJ0936 family K07095 K07095; uncharacterized protein
D Metho_1537 putative phosphoesterase, ICC K07096 K07096; uncharacterized protein
D Metho_1935 putative regulator of amino acid metabolism, contains ACT domain K07103 K07103; uncharacterized protein
D Metho_0593 putative transcriptional regulator K07108 K07108; uncharacterized protein
D Metho_2273 putative transcriptional regulator K07108 K07108; uncharacterized protein
D Metho_1726 putative transcriptional regulator K07108 K07108; uncharacterized protein
D Metho_1831 putative methanogenesis marker protein 2 K07123 K07123; uncharacterized protein
D Metho_0358 short-chain dehydrogenase of unknown substrate specificity K07124 K07124; uncharacterized protein
D Metho_1985 hypothetical protein K07129 K07129; uncharacterized protein
D Metho_2569 putative ATPase (AAA+ superfamily) K07133 K07133; uncharacterized protein
D Metho_0984 putative Fe-S center protein K07138 K07138; uncharacterized protein
D Metho_0552 PilT domain protein K07158 K07158; uncharacterized protein
D Metho_0395 TIGR00162 family protein K07159 K07159; uncharacterized protein
D Metho_0274 Zn-ribbon containing protein K07163 K07163; uncharacterized protein
D Metho_0173 hypothetical protein K08999 K08999; uncharacterized protein
D Metho_2277 hypothetical protein K09005 K09005; uncharacterized protein
D Metho_2208 hypothetical protein K09120 K09120; uncharacterized protein
D Metho_0245 hypothetical protein K09126 K09126; uncharacterized protein
D Metho_2201 TIGR00251 family protein K09131 K09131; uncharacterized protein
D Metho_0247 hypothetical protein K09135 K09135; uncharacterized protein
D Metho_2222 hypothetical protein K09137 K09137; uncharacterized protein
D Metho_1835 hypothetical protein K09139 K09139; uncharacterized protein
D Metho_0589 uncharacterized protein, PH0010 family K09141 K09141; uncharacterized protein
D Metho_0795 hypothetical protein K09148 K09148; uncharacterized protein
D Metho_1779 hypothetical protein K09149 K09149; uncharacterized protein
D Metho_0801 hypothetical protein K09150 K09150; uncharacterized protein
D Metho_1869 hypothetical protein K09152 K09152; uncharacterized protein
D Metho_0750 hypothetical protein K09154 K09154; uncharacterized protein
D Metho_0505 hypothetical protein K09157 K09157; uncharacterized protein
D Metho_0641 hypothetical protein K09700 K09700; uncharacterized protein
D Metho_0293 hypothetical protein K09717 K09717; uncharacterized protein
D Metho_0250 hypothetical protein K09721 K09721; uncharacterized protein
D Metho_2212 hypothetical protein K09725 K09725; uncharacterized protein
D Metho_1731 hypothetical protein K09726 K09726; uncharacterized protein
D Metho_2204 hypothetical protein K09727 K09727; uncharacterized protein
D Metho_1696 hypothetical protein K09728 K09728; uncharacterized protein
D Metho_1507 hypothetical protein K09729 K09729; uncharacterized protein
D Metho_1508 hypothetical protein K09729 K09729; uncharacterized protein
D Metho_0546 hypothetical protein K09730 K09730; uncharacterized protein
D Metho_1695 hypothetical protein K09731 K09731; uncharacterized protein
D Metho_0576 hypothetical protein K09732 K09732; uncharacterized protein
D Metho_2435 hypothetical protein K09736 K09736; uncharacterized protein
D Metho_0927 hypothetical protein K09740 K09740; uncharacterized protein
D Metho_0201 hypothetical protein K09743 K09743; uncharacterized protein
D Metho_2558 hypothetical protein K09745 K09745; uncharacterized protein
D Metho_0424 hypothetical protein K09746 K09746; uncharacterized protein
D Metho_0430 hypothetical protein K09746 K09746; uncharacterized protein
D Metho_2689 hypothetical protein K09746 K09746; uncharacterized protein
D Metho_2466 hypothetical protein K09746 K09746; uncharacterized protein
D Metho_2279 hypothetical protein K09779 K09779; uncharacterized protein
D Metho_1426 hypothetical protein K09791 K09791; uncharacterized protein
D Metho_1248 hypothetical protein K09799 K09799; uncharacterized protein
D Metho_1333 hypothetical protein K09807 K09807; uncharacterized protein
D Metho_0644 hypothetical protein K09807 K09807; uncharacterized protein
D Metho_2063 putative exonuclease K07502 yprB; uncharacterized protein
D Metho_2270 TIGR00153 family protein K07220 K07220; uncharacterized protein
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: June 18, 2024