+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Microbacterium sp. che218</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
B  Type III R-M system
B  Type IV R-M system
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
D      CHE218_22480 type II toxin-antitoxin system RelE/ParE family toxin	K06218 relE; mRNA interferase RelE/StbE 
D      CHE218_22470 hypothetical protein	K28297 relB_F; antitoxin RelB/F 
C    YafQ-dinJ
C    YoeB-YefM
C    HipA-HipB
C    HicA-HicB
C    YafO-YafN
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
D      CHE218_19380 type II toxin-antitoxin system ParD family antitoxin	K07746 parD1_3_4; antitoxin ParD1/3/4 
C    Doc-Phd
D      CHE218_05460 type II toxin-antitoxin system death-on-curing family toxin	K07341 doc; death on curing protein 
C    HigB-HigA
D      CHE218_21260 hypothetical protein	K18831 higA; HTH-type transcriptional regulator / antitoxin HigA 
C    MqsR-MqsA
C    VapC-VapB
D      CHE218_10860 type II toxin-antitoxin system VapC family toxin	K28279 vapC22; ribonuclease VapC22 [EC:3.1.-.-] 
D      CHE218_10870 hypothetical protein	K28280 vapB22; antitoxin VapB22 
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    SpoIISA-SpoIISB
C    Tse6-Tsi6
C    Type II TA system related factors
D      CHE218_08660 ftsZ; (GenBank) cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      CHE218_02370 gltX; (GenBank) glutamate--tRNA ligase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
C    AbiEii-AbiEi
B  Type V TA system
C    GhoT-GhoS
C    Other GhoT/OrtT toxin family protein
B  Type VI TA system
C    SocB-SocA
B  Type VII TA system
C    Hha-TomB
C    TglT-TakA
C    HepT-MntA
B  Type VIII TA system
C    SdsR-RyeA
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    CHE218_00680 cysteine desulfurase family protein	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
C    CHE218_03160 cysteine desulfurase family protein	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: May 19, 2025