+F Repair protein KO
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DNA Repair and Recombination Proteins - Methanotorris igneus
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Metig_0362 Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E Metig_0207 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
E Metig_0992 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
E Metig_0523 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
E Metig_0661 Flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E Metig_0316 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
E Metig_0331 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1
D Other NER factors
E Metig_0316 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
E Metig_0331 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1
D RFC (replication factor C)
D Other MMR factors
E Metig_0992 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
E Metig_0523 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
E Metig_0316 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
E Metig_0331 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
D Metig_0992 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
D Metig_0523 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Metig_0801 ADP-ribose diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Metig_0355 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Metig_0362 Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E Metig_0207 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Metig_1015 Xylose isomerase domain-containing protein TIM barrel K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E Metig_0278 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Metig_1468 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Metig_1397 Exodeoxyribonuclease V K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E Metig_0332 DNA double-strand break repair rad50 ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E Metig_0333 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E Metig_0278 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Metig_1468 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D AddAB pathway proteins
D Other HR factor
E Metig_0214 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E Metig_0002 DNA repair and recombination protein radA K04483 radA; DNA repair protein RadA
E Metig_0479 DNA repair and recombination protein radB K04484 radB; DNA repair protein RadB
E Metig_0338 Resolvase, Holliday junction-type K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
E Metig_0332 DNA double-strand break repair rad50 ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E Metig_0333 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11
E Metig_0052 protein of unknown function DUF87 K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
E Metig_1376 NurA domain-containing protein K25510 nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-]
E Metig_1707 ski2-type helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Metig_0780 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F Metig_0278 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F Metig_1468 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D Metig_0027 helicase c2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D Metig_1246 DEAD/H associated domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D Metig_0801 ADP-ribose diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Metig_0355 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
D Metig_0923 protein of unknown function DUF650 K22585 nreA; DNA repair protein NreA
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024