+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Maniola jurtina (meadow brown)</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
E        123881238 mRNA cap guanine-N7 methyltransferase	K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56] 
E        123867912 mRNA-capping enzyme isoform X1	K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74] 
E        123874522 cyclin-dependent kinase 7	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        123864879 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 isoform X1	K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296] 
E        123864632 RNA guanine-N7 methyltransferase activating subunit	K18708 FAM103A1; RNMT-activating mini protein 
D      Cap binding complex
E        123874222 nuclear cap-binding protein subunit 1	K12882 NCBP1; nuclear cap-binding protein subunit 1 
E        123864328 nuclear cap-binding protein subunit 2	K12883 NCBP2; nuclear cap-binding protein subunit 2 
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
E        123879466 cleavage and polyadenylation specificity factor subunit 5	K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5 
E        123876410 cleavage and polyadenylation specificity factor subunit 6 isoform X1	K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7 
D      Pre-mRNA cleavage factor IIm (CFIIm)
E        123874861 protein CLP1 homolog	K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] 
D      Cleavage and polyadenylation specificity factor (CPSF) complex
E        123865022 cleavage and polyadenylation specificity factor subunit 1 isoform X1	K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1 
E        123875123 probable cleavage and polyadenylation specificity factor subunit 2	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        123875909 cleavage and polyadenylation specificity factor 73	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        123873629 pre-mRNA 3' end processing protein WDR33	K15542 PFS2; polyadenylation factor subunit 2 
E        123866075 WD repeat-containing protein 82	K14962 WDR82; COMPASS component SWD2 
E        123871301 serine/threonine-protein phosphatase alpha-2 isoform isoform X1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        123872936 serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        123866313 RNA polymerase II subunit A C-terminal domain phosphatase SSU72	K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] 
D      Cleavage stimulation factor (CSTF) complex
E        123878422 cleavage stimulation factor subunit 1	K14406 CSTF1; cleavage stimulation factor subunit 1 
E        123869118 cleavage stimulation factor subunit 2 tau variant	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        123871047 protein suppressor of forked	K14408 CSTF3; cleavage stimulation factor subunit 3 
E        123872942 symplekin isoform X1	K06100 SYMPK; symplekin 
D      U7-dependent histone pre-mRNA processing factors
E        123864175 small nuclear ribonucleoprotein-associated protein B	K11086 SNRPB; small nuclear ribonucleoprotein B and B' 
E        123870657 small nuclear ribonucleoprotein Sm D3	K11088 SNRPD3; small nuclear ribonucleoprotein D3 
E        123868171 probable small nuclear ribonucleoprotein E	K11097 SNRPE; small nuclear ribonucleoprotein E 
E        123868554 small nuclear ribonucleoprotein F	K11098 SNRPF; small nuclear ribonucleoprotein F 
E        123877183 probable small nuclear ribonucleoprotein G	K11099 SNRPG; small nuclear ribonucleoprotein G 
E        123864246 U7 snRNA-associated Sm-like protein LSm10	K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10 
E        123864269 U7 snRNA-associated Sm-like protein LSm11	K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11 
E        123875123 probable cleavage and polyadenylation specificity factor subunit 2	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        123875909 cleavage and polyadenylation specificity factor 73	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        123869118 cleavage stimulation factor subunit 2 tau variant	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        123872942 symplekin isoform X1	K06100 SYMPK; symplekin 
E        123872780 histone RNA hairpin-binding protein	K18710 SLBP; histone RNA hairpin-binding protein 
D      DRB sensitivity inducing factor (DSIF) complex
E        123872391 transcription elongation factor SPT4	K15171 SUPT4H1; transcription elongation factor SPT4 
E        123864297 transcription elongation factor SPT5	K15172 SUPT5H; transcription elongation factor SPT5 
D      N6-methyltransferase complex
E        123865241 N6-adenosine-methyltransferase subunit METTL3	K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348] 
E        123873911 N6-adenosine-methyltransferase non-catalytic subunit	K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit 
E        123875684 N(6)-adenine-specific methyltransferase METTL4 isoform X1	K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72] 
E        123872774 U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase	K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346] 
E        123873950 pre-mRNA-splicing regulator female-lethal(2)D	K22824 WTAP; pre-mRNA-splicing regulator WTAP 
E        123868077 protein virilizer	K22910 VIRMA; protein virilizer 
E        123875954 RNA-binding protein spenito	K13190 RBM15; RNA-binding protein 15 
E        123866832 E3 ubiquitin-protein ligase Hakai isoform X1	K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27] 
D      Poly(A) addition factors
E        123878223 poly(A) polymerase type 3 isoform X1	K14376 PAP; poly(A) polymerase [EC:2.7.7.19] 
E        123874577 poly(A) RNA polymerase gld-2 homolog A-like	K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19] 
D      Negative regulators of mRNA 3' end processing
E        123869411 BRCA1-associated RING domain protein 1-like	K10683 BARD1; BRCA1-associated RING domain protein 1 
E        123864310 TAR DNA-binding protein 43-like	K23600 TARDBP; TAR DNA-binding protein 43 
E        123868150 TAR DNA-binding protein 43-like	K23600 TARDBP; TAR DNA-binding protein 43 
E        123879809 TAR DNA-binding protein 43-like	K23600 TARDBP; TAR DNA-binding protein 43 
C    Other processing factors
D      123878775 DNA/RNA-binding protein KIN17	K13102 KIN; DNA/RNA-binding protein KIN17 
D      123868314 methyltransferase-like protein 22 isoform X1	K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-] 
D      123872573 serrate RNA effector molecule homolog isoform X1	K27103 SRRT; serrate RNA effector molecule 
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
E        123879047 RNA-binding protein 8A	K12876 RBM8A; RNA-binding protein 8A 
E        123864681 protein mago nashi	K12877 MAGOH; protein mago nashi 
E        123872777 THO complex subunit 4-B isoform X1	K12881 THOC4; THO complex subunit 4 
E        123871331 ATP-dependent RNA helicase WM6	K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7] 
E        123874757 eukaryotic initiation factor 4A-III	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        123876651 coiled-coil domain-containing protein 174	K25178 CCDC174; coiled-coil domain-containing protein 174 
E        123870329 histone deacetylase complex subunit SAP18	K14324 SAP18; histone deacetylase complex subunit SAP18 
E        123875276 pinin	K13114 PNN; pinin 
E        123872595 RNA-binding protein with serine-rich domain 1-A-like isoform X1	K14325 RNPS1; RNA-binding protein with serine-rich domain 1 
E        123867231 serine/arginine repetitive matrix protein 1-like isoform X1	K13171 SRRM1; serine/arginine repetitive matrix protein 1 
D      TREX complex
E        123868530 THO complex subunit 1 isoform X1	K12878 THOC1; THO complex subunit 1 
E        123866159 THO complex subunit 2 isoform X1	K12879 THOC2; THO complex subunit 2 
E        123877822 THO complex subunit 3 isoform X1	K12880 THOC3; THO complex subunit 3 
E        123872777 THO complex subunit 4-B isoform X1	K12881 THOC4; THO complex subunit 4 
E        123872638 THO complex subunit 5 homolog	K13174 THOC5; THO complex subunit 5 
E        123880976 THO complex subunit 6	K13175 THOC6; THO complex subunit 6 
E        123870196 THO complex subunit 7 homolog	K13176 THOC7; THO complex subunit 7 
D      TREX-2 complex
E        123867551 PCI domain-containing protein 2 homolog	K23801 PCID2; nuclear mRNA export protein PCID2/THP1 
E        123879928 PCI domain-containing protein 2 homolog	K23801 PCID2; nuclear mRNA export protein PCID2/THP1 
E        123880494 PCI domain-containing protein 2 homolog	K23801 PCID2; nuclear mRNA export protein PCID2/THP1 
E        123879262 transcription and mRNA export factor ENY2-like	K11368 ENY2; enhancer of yellow 2 transcription factor 
E        123868549 myosin light chain 3, skeletal muscle isoform-like	K10840 CETN2; centrin-2 
E        123878805 caltractin-like isoform X1	K10840 CETN2; centrin-2 
D      Nuclear pore complex
E        123868386 nucleoprotein TPR-like isoform X1	K09291 TPR; nucleoprotein TPR 
E        123880519 nucleoprotein TPR-like	K09291 TPR; nucleoprotein TPR 
E        123865434 protein Rae1	K14298 RAE1; mRNA export factor 
E        123875361 protein SEC13 homolog	K14004 SEC13; protein transport protein SEC13 
E        123871541 nuclear pore complex protein Nup85	K14304 NUP85; nuclear pore complex protein Nup85 
E        123874778 nucleoporin Nup43	K14305 NUP43; nuclear pore complex protein Nup43 
E        123866362 nuclear pore complex protein Nup50 isoform X1	K14295 NUP50; nuclear pore complex protein Nup50 
E        123864934 probable nucleoporin Nup54	K14308 NUP54; nuclear pore complex protein Nup54 
E        123865770 nuclear pore glycoprotein p62-like	K14306 NUP62; nuclear pore complex protein Nup62 
E        123871279 nuclear pore complex protein Nup88 isoform X1	K14318 NUP88; nuclear pore complex protein Nup88 
E        123868403 nuclear pore complex protein Nup93-like	K14309 NUP93; nuclear pore complex protein Nup93 
E        123879546 nuclear pore complex protein Nup98-Nup96 isoform X1	K14297 NUP98; nuclear pore complex protein Nup98-Nup96 
E        123870168 nuclear pore complex protein Nup107	K14301 NUP107; nuclear pore complex protein Nup107 
E        123875342 nuclear pore complex protein Nup133	K14300 NUP133; nuclear pore complex protein Nup133 
E        123875148 nucleoporin Nup188	K14311 NUP188; nuclear pore complex protein Nup188 
E        123880847 nuclear pore complex protein Nup154	K14312 NUP155; nuclear pore complex protein Nup155 
E        123868406 nuclear pore complex protein Nup160 homolog	K14303 NUP160; nuclear pore complex protein Nup160 
E        123866965 nucleoporin Nup35	K14313 NUP35; nuclear pore complex protein Nup53 
E        123864878 nuclear pore complex protein Nup205	K14310 NUP205; nuclear pore complex protein Nup205 
E        123876150 nuclear pore complex protein Nup58	K14307 NUPL1; nucleoporin p58/p45 
E        123868919 nucleoporin NDC1	K14315 NDC1; nucleoporin NDC1 
E        123875537 nucleoporin SEH1	K14299 SEH1; nucleoporin SEH1 
E        123874068 aladin-like	K14320 AAAS; aladin 
E        123874846 mRNA export factor Gle1	K18723 GLE1; nucleoporin GLE1 
E        123876797 nuclear RNA export factor 1-like	K14284 NXF; nuclear RNA export factor 
E        123873156 nuclear RNA export factor 1	K14284 NXF; nuclear RNA export factor 
E        123874899 NTF2-related export protein	K14285 NXT1_2; NTF2-related export protein 1/2 
D      Ran-mediated transport factors
E        123880796 GTP-binding nuclear protein Ran	K07936 RAN; GTP-binding nuclear protein Ran 
E        123867784 acidic leucine-rich nuclear phosphoprotein 32 family member A	K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D 
E        123865574 ELAV-like protein 4	K13208 ELAVL2_3_4; ELAV like protein 2/3/4 
E        123869352 ELAV-like protein 2	K13208 ELAVL2_3_4; ELAV like protein 2/3/4 
E        123869368 ELAV-like protein 1	K13208 ELAVL2_3_4; ELAV like protein 2/3/4 
E        123873371 protein elav	K13208 ELAVL2_3_4; ELAV like protein 2/3/4 
E        123873645 FAS-associated factor 2	K18726 FAF2; FAS-associated factor 2 
E        123875645 transitional endoplasmic reticulum ATPase TER94 isoform X1	K13525 VCP; transitional endoplasmic reticulum ATPase 
E        123868674 protein N-lysine methyltransferase METTL21D-like isoform X1	K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-] 
E        123869796 exportin-1	K14290 XPO1; exportin-1 
E        123878591 exportin-7-B	K18460 XPO7; exportin-7 
E        123879494 ran GTPase-activating protein 1	K14319 RANGAP1; Ran GTPase-activating protein 1 
D      eIF4F and regulatory proteins
E        123866972 eukaryotic translation initiation factor 4E1-like	K03259 EIF4E; translation initiation factor 4E 
E        123868767 eukaryotic translation initiation factor 4E type 2 isoform X1	K03259 EIF4E; translation initiation factor 4E 
E        123868678 eukaryotic initiation factor 4A	K03257 EIF4A; translation initiation factor 4A 
E        123866033 eukaryotic translation initiation factor 4 gamma 2	K03260 EIF4G; translation initiation factor 4G 
E        123869140 eukaryotic translation initiation factor 4B isoform X1	K03258 EIF4B; translation initiation factor 4B 
E        123871451 eukaryotic translation initiation factor 4H isoform X1	K24086 EIF4H; translation initiation factor 4H 
E        123873532 eukaryotic translation initiation factor 4E-binding protein	K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2 
E        123880490 protein angel isoform X1	K18729 ANGEL; protein angel 
E        123868929 fragile X mental retardation syndrome-related protein 1 isoform X1	K15516 FMR; fragile X mental retardation protein 
E        123879727 cytoplasmic FMR1-interacting protein	K05749 CYFIP; cytoplasmic FMR1 interacting protein 
E        123868730 uncharacterized protein LOC123868730 isoform X1	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        123879574 cytoplasmic polyadenylation element-binding protein 2-like isoform X1	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        123864609 ATP-dependent RNA helicase bel isoform X1	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        123870671 polyadenylate-binding protein 1-A	K13126 PABPC; polyadenylate-binding protein 
E        123867133 polyadenylate-binding protein-interacting protein 1 isoform X1	K14322 PAIP1; polyadenylate-binding protein-interacting protein 1 
E        123875009 helicase SKI2W	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        123869143 deformed epidermal autoregulatory factor 1	K23041 DEAF1; deformed epidermal autoregulatory factor 1 
E        123876425 malignant T-cell-amplified sequence 1 homolog	K07575 MCTS; malignant T-cell-amplified sequence 
E        123872646 density-regulated protein homolog	K24272 DENR; density-regulated protein 
D      APOBEC1-ACF complex
D      Other transport factors
E        123872250 partner of Y14 and mago	K14294 WIBG; partner of Y14 and mago 
E        123869081 heterogeneous nuclear ribonucleoprotein A1-like	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        123869082 heterogeneous nuclear ribonucleoprotein 87F-like	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        123874319 heterogeneous nuclear ribonucleoprotein 27C isoform X1	K14411 MSI; RNA-binding protein Musashi 
E        123878835 RNA-binding protein Musashi homolog 2-like isoform X1	K14411 MSI; RNA-binding protein Musashi 
E        123880913 RNA-binding protein Musashi homolog Rbp6 isoform X1	K14411 MSI; RNA-binding protein Musashi 
E        123864772 protein HBS1	K14416 HBS1; elongation factor 1 alpha-like protein 
E        123881215 protein pelota	K06965 PELO; protein pelota 
E        123875428 polyadenylate-binding protein 2-B	K14396 PABPN1; polyadenylate-binding protein 2 
E        123866304 DEAD-box helicase Dbp80	K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7] 
E        123880907 pre-mRNA-splicing factor syf1 homolog	K12867 SYF1; pre-mRNA-splicing factor SYF1 
E        123876632 SAP domain-containing ribonucleoprotein	K18732 SARNP; SAP domain-containing ribonucleoprotein 
E        123878048 regulator of chromosome condensation isoform X1	K11493 RCC1; regulator of chromosome condensation 
E        123865228 la-related protein 6	K18733 LARP6; la-related protein 6 
E        123877281 transcriptional activator protein Pur-beta isoform X1	K21772 PURA; transcriptional activator protein Pur-alpha 
E        123868378 leukocyte receptor cluster member 8 homolog isoform X1	K23802 LENG8; SAC3 family protein LENG8/THP3 
C    Surveillance factors
D      Surveillance complex
E        123878623 eukaryotic peptide chain release factor subunit 1 isoform X1	K03265 ETF1; peptide chain release factor subunit 1 
E        123871795 eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1	K03267 ERF3; peptide chain release factor subunit 3 
E        123874515 regulator of nonsense transcripts 1	K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
E        123868382 regulator of nonsense transcripts 2 isoform X1	K14327 UPF2; regulator of nonsense transcripts 2 
D      Protein phosphatase 2A
E        123873526 serine/threonine-protein phosphatase 2A catalytic subunit beta isoform isoform X1	K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] 
E        123877673 serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        123877720 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform	K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B 
E        123864763 uncharacterized protein LOC123864763 isoform X1	K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B'' 
E        123865654 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma-like isoform X1	K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B'' 
E        123874892 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
E        123875246 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like isoform X1	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
D      Other surveillance factors
E        123868472 serine/threonine-protein kinase SMG1	K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1] 
E        123874174 protein SMG5	K11125 SMG5; protein SMG5 
E        123868724 protein SMG8	K18734 SMG8; protein SMG8 
E        123873204 protein SMG9-like	K18735 SMG9; protein SMG9 
E        123874568 probable ATP-dependent RNA helicase DHX34 isoform X1	K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6] 
E        123881122 GTP-binding protein 1 isoform X1	K24887 GTPBP1; GTP-binding protein 1 
C    Factors involved in mRNA localization
D      Cargo complex
E        123871971 protein penguin	K14844 PUF6; pumilio homology domain family member 6 
E        123879234 unconventional myosin-Va isoform X1	K10357 MYO5; myosin V 
E        123875707 protein bicaudal D isoform X1	K18739 BICD; protein bicaudal D 
E        123866379 piRNA biogenesis protein EXD1-like	K18740 EXD1; exonuclease 3'-5' domain-containing protein 1 
E        123871276 egalitarian protein homolog	K18740 EXD1; exonuclease 3'-5' domain-containing protein 1 
D      Factors that have mRNA localization signals
E        123871897 actin, cytoplasmic A3a	K05692 ACTB_G1; actin beta/gamma 1 
E        123871898 actin-5C	K05692 ACTB_G1; actin beta/gamma 1 
E        123868541 myc protein	K04377 MYC; Myc proto-oncogene protein 
E        123881102 T-box transcription factor TBX6-like	K10180 TBX6; T-box protein 6 
E        123873864 enhancer of split mbeta protein-like	K09090 HESN; hairy and enhancer of split, invertebrate 
E        123872714 protein hairy-like	K09090 HESN; hairy and enhancer of split, invertebrate 
E        123873695 enhancer of split mbeta protein-like	K09090 HESN; hairy and enhancer of split, invertebrate 
E        123873856 class E basic helix-loop-helix protein 40-like	K09090 HESN; hairy and enhancer of split, invertebrate 
E        123872257 uncharacterized protein LOC123872257	K09090 HESN; hairy and enhancer of split, invertebrate 
D      Trans-acting binding proteins
E        123865532 far upstream element-binding protein 1 isoform X1	K13210 FUBP; far upstream element-binding protein 
E        123864306 elongation factor 1-alpha 2	K03231 EEF1A; elongation factor 1-alpha 
E        123870938 elongation factor 1-alpha	K03231 EEF1A; elongation factor 1-alpha 
E        123873318 elongation factor 1-gamma	K03233 EEF1G; elongation factor 1-gamma 
E        123868436 arf-GAP domain and FG repeat-containing protein 1	K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1 
E        123875172 double-stranded RNA-binding protein Staufen homolog 2 isoform X1	K17597 STAU; double-stranded RNA-binding protein Staufen 
E        123867066 polypyrimidine tract-binding protein 2 isoform X1	K13218 PTBP1; polypyrimidine tract-binding protein 1 
E        123869244 RNA-binding protein squid isoform X1	K03102 SQD; squid 
E        123868730 uncharacterized protein LOC123868730 isoform X1	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        123879574 cytoplasmic polyadenylation element-binding protein 2-like isoform X1	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
D      Other mRNA localization factors
E        123868929 fragile X mental retardation syndrome-related protein 1 isoform X1	K15516 FMR; fragile X mental retardation protein 
E        123879727 cytoplasmic FMR1-interacting protein	K05749 CYFIP; cytoplasmic FMR1 interacting protein 
E        123867643 poly(rC)-binding protein 3 isoform X1	K21444 PCBP3_4; poly(rC)-binding protein 3/4 
E        123866298 translation initiation factor IF-2-like	K18743 CAPRIN1; caprin-1 
E        123869709 CUGBP Elav-like family member 1 isoform X1	K02177 BRU; bruno 
E        123865363 maternal protein exuperantia isoform X1	K18745 EXU; maternal protein exuperantia 
E        123880274 Y-box factor homolog	K09276 YBX1; Y-box-binding protein 1 
E        123871133 sex-lethal homolog isoform X1	K18747 SXL; protein sex-lethal 
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
E        123866846 5'-3' exoribonuclease 1 isoform X1	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        123877393 protein argonaute-2 isoform X1	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        123869496 protein argonaute-2-like isoform X1	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        123866972 eukaryotic translation initiation factor 4E1-like	K03259 EIF4E; translation initiation factor 4E 
E        123868767 eukaryotic translation initiation factor 4E type 2 isoform X1	K03259 EIF4E; translation initiation factor 4E 
E        123874515 regulator of nonsense transcripts 1	K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
E        123864609 ATP-dependent RNA helicase bel isoform X1	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        123869552 ATP-dependent RNA helicase me31b	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        123874325 RNA-binding protein MEX3B	K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
E        123868192 protein LSM14 homolog B-like isoform X1	K18749 LSM14; protein LSM14 
E        123880274 Y-box factor homolog	K09276 YBX1; Y-box-binding protein 1 
E        123881011 LIM domain-containing protein jub	K16682 AJUBA; LIM domain-containing protein 
E        123875012 RNA helicase Mov10l1-like	K18422 MOV10; helicase MOV-10 [EC:5.6.2.5] 
E        123870132 transportin-1	K18752 TNPO1; transportin-1 
E        123868472 serine/threonine-protein kinase SMG1	K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1] 
E        123874174 protein SMG5	K11125 SMG5; protein SMG5 
E        123873331 protein TIS11 isoform X1	K15308 TTP; tristetraprolin 
E        123867005 protein lin-28 homolog	K18754 LIN28; protein lin-28 
E        123869081 heterogeneous nuclear ribonucleoprotein A1-like	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        123869082 heterogeneous nuclear ribonucleoprotein 87F-like	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        123865867 cAMP-dependent protein kinase catalytic subunit 1-like	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        123866021 cAMP-dependent protein kinase catalytic subunit beta-like	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        123866022 cAMP-dependent protein kinase catalytic subunit 1-like	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        123869019 cAMP-dependent protein kinase catalytic subunit 1-like	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        123870342 cAMP-dependent protein kinase catalytic subunit 1	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        123879549 la-related protein 1 isoform X1	K18757 LARP1; la-related protein 1 
D      P-body specific factors
E        123874275 m7GpppN-mRNA hydrolase	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        123872750 mRNA-decapping enzyme 1B	K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-] 
E        123870292 U6 snRNA-associated Sm-like protein LSm1	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        123871053 U6 snRNA-associated Sm-like protein LSm2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        123873952 U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        123879654 U6 snRNA-associated Sm-like protein LSm4	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        123871943 U6 snRNA-associated Sm-like protein LSm5	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        123865489 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        123873777 U6 snRNA-associated Sm-like protein LSm7	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        123869046 U6 snRNA-associated Sm-like protein LSm8	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
E        123873365 kinesin light chain isoform X1	K10407 KLC; kinesin light chain 
E        123879234 unconventional myosin-Va isoform X1	K10357 MYO5; myosin V 
E        123866650 tubulin alpha chain-like isoform X1	K07374 TUBA; tubulin alpha 
E        123867581 tubulin alpha-1A chain isoform X1	K07374 TUBA; tubulin alpha 
E        123877437 tubulin alpha chain isoform X1	K07374 TUBA; tubulin alpha 
E        123880179 tubulin alpha-1 chain-like	K07374 TUBA; tubulin alpha 
E        123870439 tubulin alpha chain-like isoform X1	K07374 TUBA; tubulin alpha 
E        123868730 uncharacterized protein LOC123868730 isoform X1	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        123879574 cytoplasmic polyadenylation element-binding protein 2-like isoform X1	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        123871878 protein Gawky isoform X1	K18412 TNRC6; trinucleotide repeat-containing gene 6 protein 
E        123877391 CCR4-NOT transcription complex subunit 1-like isoform X1	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        123880337 CCR4-NOT transcription complex subunit 1-like isoform X1	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        123876752 regulator of gene activity isoform X1	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        123872406 CCR4-NOT transcription complex subunit 3 isoform X1	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        123877333 uncharacterized protein LOC123877333 isoform X1	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        123869194 CCR4-NOT transcription complex subunit 6 isoform X1	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        123866320 CCR4-NOT transcription complex subunit 7-like isoform X1	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        123866321 CCR4-NOT transcription complex subunit 7-like	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        123867946 DIS3-like exonuclease 2	K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-] 
E        123872863 PAN2-PAN3 deadenylation complex catalytic subunit PAN2-like isoform X1	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        123880695 PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
E        123878802 protein Tob1	K14443 TOB; protein Tob/BTG 
E        123875376 enhancer of mRNA-decapping protein 3	K12615 EDC3; enhancer of mRNA-decapping protein 3 
E        123868382 regulator of nonsense transcripts 2 isoform X1	K14327 UPF2; regulator of nonsense transcripts 2 
E        123875889 protein wech	K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27] 
E        123874849 DNA-directed RNA polymerase II subunit RPB7	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
E        123864774 YTH domain-containing family protein 3-like isoform X1	K20102 YTHDF; YTH domain-containing family protein 
D      Stress granule specific factors
E        123875135 nucleolysin TIAR	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        123879338 nucleolysin TIA-1	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        123870671 polyadenylate-binding protein 1-A	K13126 PABPC; polyadenylate-binding protein 
E        123875172 double-stranded RNA-binding protein Staufen homolog 2 isoform X1	K17597 STAU; double-stranded RNA-binding protein Staufen 
E        123868929 fragile X mental retardation syndrome-related protein 1 isoform X1	K15516 FMR; fragile X mental retardation protein 
E        123869242 ras GTPase-activating protein-binding protein 2	K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3] 
E        123864701 eukaryotic translation initiation factor 2A	K15026 EIF2A; translation initiation factor 2A 
E        123872113 eukaryotic translation initiation factor 3 subunit B	K03253 EIF3B; translation initiation factor 3 subunit B 
E        123868678 eukaryotic initiation factor 4A	K03257 EIF4A; translation initiation factor 4A 
E        123874757 eukaryotic initiation factor 4A-III	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        123869140 eukaryotic translation initiation factor 4B isoform X1	K03258 EIF4B; translation initiation factor 4B 
E        123866033 eukaryotic translation initiation factor 4 gamma 2	K03260 EIF4G; translation initiation factor 4G 
E        123870246 ribosomal protein S6 kinase 2 beta	K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
E        123873527 guanine nucleotide-binding protein subunit beta-like protein	K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein 
E        123876797 nuclear RNA export factor 1-like	K14284 NXF; nuclear RNA export factor 
E        123873156 nuclear RNA export factor 1	K14284 NXF; nuclear RNA export factor 
E        123874460 histone deacetylase 6 isoform X1	K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98] 
E        123866516 tudor domain-containing protein 3	K18404 TDRD3; tudor domain-containing protein 3 
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
E        123872750 mRNA-decapping enzyme 1B	K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-] 
E        123874275 m7GpppN-mRNA hydrolase	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        123869552 ATP-dependent RNA helicase me31b	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        123875376 enhancer of mRNA-decapping protein 3	K12615 EDC3; enhancer of mRNA-decapping protein 3 
D      Lsm complex
E        123870292 U6 snRNA-associated Sm-like protein LSm1	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        123871053 U6 snRNA-associated Sm-like protein LSm2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        123873952 U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        123879654 U6 snRNA-associated Sm-like protein LSm4	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        123871943 U6 snRNA-associated Sm-like protein LSm5	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        123865489 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        123873777 U6 snRNA-associated Sm-like protein LSm7	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        123869046 U6 snRNA-associated Sm-like protein LSm8	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
D      5' exonucleases
E        123866846 5'-3' exoribonuclease 1 isoform X1	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        123874934 5'-3' exoribonuclease 2 homolog isoform X1	K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-] 
D      Other 5'-3' decay factors
E        123878174 m7GpppX diphosphatase	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
C    3'-5' decay
D      Core exosome factors
E        123877859 exosome complex component CSL4	K07573 CSL4; exosome complex component CSL4 
E        123864156 exosome complex component RRP4	K03679 RRP4; exosome complex component RRP4 
E        123872322 exosome complex component RRP40	K03681 RRP40; exosome complex component RRP40 
E        123865366 exosome complex component RRP41	K11600 RRP41; exosome complex component RRP41 
E        123874741 exosome complex component RRP46	K12590 RRP46; exosome complex component RRP46 
E        123865164 exosome complex component MTR3 isoform X1	K12587 MTR3; exosome complex component MTR3 
E        123876794 exosome complex component RRP42	K12589 RRP42; exosome complex component RRP42 
E        123866208 exosome complex component RRP43-like	K12586 RRP43; exosome complex component RRP43 
E        123866196 exosome complex component RRP45	K03678 RRP45; exosome complex component RRP45 
D      Exosome cofactors
E        123867432 exosome complex exonuclease RRP44 isoform X1	K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] 
E        123880694 exosome component 10 isoform X1	K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-] 
E        123872992 nuclear nucleic acid-binding protein C1D-like	K12592 C1D; exosome complex protein LRP1 
E        123864445 M-phase phosphoprotein 6	K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type 
D      TRAMP complex
E        123865433 non-canonical poly(A) RNA polymerase protein Trf4-1-like	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        123877625 exosome RNA helicase MTR4	K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6] 
D      Ski complex
E        123875009 helicase SKI2W	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        123880982 tetratricopeptide repeat protein 37	K12600 SKI3; superkiller protein 3 
E        123874473 WD repeat-containing protein 61-like	K12602 WDR61; WD repeat-containing protein 61 
E        123874474 WD repeat-containing protein 61-like	K12602 WDR61; WD repeat-containing protein 61 
D      Ccr4-NOT complex
E        123869194 CCR4-NOT transcription complex subunit 6 isoform X1	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        123877391 CCR4-NOT transcription complex subunit 1-like isoform X1	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        123880337 CCR4-NOT transcription complex subunit 1-like isoform X1	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        123876752 regulator of gene activity isoform X1	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        123872406 CCR4-NOT transcription complex subunit 3 isoform X1	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        123877333 uncharacterized protein LOC123877333 isoform X1	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        123866320 CCR4-NOT transcription complex subunit 7-like isoform X1	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        123866321 CCR4-NOT transcription complex subunit 7-like	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        123876837 CCR4-NOT transcription complex subunit 9	K12606 RCD1; CCR4-NOT transcription complex subunit 9 
E        123870804 CCR4-NOT transcription complex subunit 10	K12607 CNOT10; CCR4-NOT transcription complex subunit 10 
D      Pan complex
E        123872863 PAN2-PAN3 deadenylation complex catalytic subunit PAN2-like isoform X1	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        123880695 PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
D      Other 3'-5' decay factors
E        123880172 pre-piRNA 3'-exonuclease trimmer-like	K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] 
E        123871515 poly(A)-specific ribonuclease PARN-like isoform X1	K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] 
E        123874107 ATP-dependent DNA/RNA helicase DHX36-like	K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6] 
E        123878802 protein Tob1	K14443 TOB; protein Tob/BTG 
E        123878174 m7GpppX diphosphatase	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
E        123864476 2',5'-phosphodiesterase 12	K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-] 
E        123873124 protein Smaug	K27396 SMG; protein Smaug 
E        123875420 focadhesin	K27498 FOCAD; focadhesin 
C    Other degradation factors
D      RNases
E        123873944 probable ribonuclease ZC3H12D isoform X1	K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-] 
#
A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        123872980 ribonuclease 3	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        123870308 probable oligoribonuclease	K13288 orn; oligoribonuclease [EC:3.1.-.-] 
D      Helicases
D      Other RNA degradosome components
E        123880224 alpha-enolase-like	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        123872781 enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        123875251 polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1	K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 
E        123875082 ATP-dependent 6-phosphofructokinase isoform X1	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        123878597 heat shock 70 kDa protein cognate 5	K04043 dnaK; molecular chaperone DnaK 
E        123874976 63 kDa chaperonin, mitochondrial-like	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
E        123873712 heat shock protein 60A-like	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
D      Others
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
E        123864156 exosome complex component RRP4	K03679 RRP4; exosome complex component RRP4 
E        123877859 exosome complex component CSL4	K07573 CSL4; exosome complex component CSL4 
D      Cofactors
E        123865366 exosome complex component RRP41	K11600 RRP41; exosome complex component RRP41 
E        123876794 exosome complex component RRP42	K12589 RRP42; exosome complex component RRP42 
D      Others
!
#<hr>
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#Last updated: April 25, 2024