+F Repair protein KO
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DNA Repair and Recombination Proteins - Mycobacterium leprae TN
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D ML1151 ogt; probable methylated-DNA-protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E ML1675 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E ML1351 possible 3-methylpurine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E ML1920 mutY; probable DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E ML2301 nth; putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E ML2157 probable DNA helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D ML1028 dut; probable deoxyuridine triphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D ML1151 ogt; probable methylated-DNA-protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E ML1675 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E ML1105 conserved hypothetical protein. K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E ML1351 possible 3-methylpurine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E ML1920 mutY; probable DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E ML1066 tagA; DNA-3-methyladenine glycosidase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E ML1658 fpg; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E ML2301 nth; putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E ML1889 putataive endonuclease IV (apurinase) K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
D DNA ligase
E ML1705 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E ML1381 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E ML1392 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E ML1387 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E ML0562 uvrC; putative excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E ML0153 uvrD; putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ML0637 uvrD2; putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ML1381 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E ML1705 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F ML1891 rpoB; [beta] subunit of RNA polymerase K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F ML1890 rpoC; [beta]' subunit of RNA polymerase K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F ML1957 rpoA; [alpha] subunit of RNA polymerase K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F ML0542 conserved hypothetical protein K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F ML0252 mfd; putative transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E ML1940 xseA; exonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E ML1941 xseB; exonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E ML1207 dnaE; DNA polymerase III, [alpha] subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E ML0002 dnaN; putative DNA polymerase III, [beta] subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E ML0603 putative lipoprotein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E ML0202 conserved hypothetical protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E ML2335 dnaZX; DNA polymerase III, subunit [gamma/tau] K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E ML1705 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E ML0153 uvrD; putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ML0637 uvrD2; putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ML2684 ssb; single strand binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E ML0987 recA; RecA protein K03553 recA; recombination protein RecA
E ML0482 ruvA; Holliday junction DNA helicase component K03550 ruvA; holliday junction DNA helicase RuvA
E ML0483 ruvB; Holliday junction helicase component K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E ML0481 ruvC; crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E ML0548 priA; putative primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E ML0987 recA; RecA protein K03553 recA; recombination protein RecA
E ML0003 recF; putative DNA replication and SOS induction protein K03629 recF; DNA replication and repair protein RecF
E ML1671 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E ML0633 conserved hypothetical protein K03584 recO; DNA repair protein RecO (recombination protein O)
E ML2329 recR; DNA repair protein K06187 recR; recombination protein RecR
E ML1360 recN; recombination and DNA repair K03631 recN; DNA repair protein RecN (Recombination protein N)
E ML0482 ruvA; Holliday junction DNA helicase component K03550 ruvA; holliday junction DNA helicase RuvA
E ML0483 ruvB; Holliday junction helicase component K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E ML0481 ruvC; crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F ML0006 gyrA; putative DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F ML0005 gyrB; putative DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F ML0200 topA; putative DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F ML1683 probable histone-like protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F ML0633 conserved hypothetical protein K03584 recO; DNA repair protein RecO (recombination protein O)
F ML2329 recR; DNA repair protein K06187 recR; recombination protein RecR
F ML1705 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F ML1392 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F ML1387 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D ML0987 recA; RecA protein K03553 recA; recombination protein RecA
D ML1003 lexA; LexA, SOS repressor protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D ML1360 recN; recombination and DNA repair K03631 recN; DNA repair protein RecN (Recombination protein N)
D ML2684 ssb; single strand binding protein K03111 ssb; single-strand DNA-binding protein
D ML0988 recX; putative regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D ML1682 conserved hypothetical protein K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D ML1028 dut; probable deoxyuridine triphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D ML1734 nrdE; ribonucleoside diphosphate reductase [alpha] chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D ML1731 nrdF; ribonucleotide reductase small subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024