+F Repair protein KO
#
DNA Repair and Recombination Proteins - Megasphaera massiliensis
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D LCQ47_02480 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E LCQ47_07650 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E LCQ47_11620 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LCQ47_11585 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D LCQ47_05855 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LCQ47_12110 (deoxy)nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LCQ47_08505 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LCQ47_00555 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D LCQ47_02480 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E LCQ47_06085 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E LCQ47_07650 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E LCQ47_11620 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LCQ47_00700 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E LCQ47_00035 mutM; bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E LCQ47_11585 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E LCQ47_02120 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E LCQ47_04460 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E LCQ47_00430 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E LCQ47_01580 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E LCQ47_03115 excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E LCQ47_11640 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E LCQ47_11635 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
E LCQ47_11645 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
E LCQ47_01585 pcrA; DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LCQ47_02460 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LCQ47_01580 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F LCQ47_06050 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F LCQ47_06045 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F LCQ47_05870 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F LCQ47_02625 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F LCQ47_01030 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E LCQ47_02945 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E LCQ47_10595 endonuclease MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E LCQ47_02940 mutL; DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E LCQ47_04655 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E LCQ47_04650 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E LCQ47_04795 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E LCQ47_11360 PolC-type DNA polymerase III K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E LCQ47_07805 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E LCQ47_11350 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E LCQ47_08520 DNA polymerase III subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E LCQ47_04725 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E LCQ47_06405 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E LCQ47_08010 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E LCQ47_07680 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E LCQ47_01580 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E LCQ47_01585 pcrA; DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LCQ47_02460 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LCQ47_08235 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E LCQ47_11540 very short patch repair endonuclease K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E LCQ47_00320 ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E LCQ47_10035 recA; recombinase RecA K03553 recA; recombination protein RecA
E LCQ47_10795 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E LCQ47_10800 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E LCQ47_10790 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E LCQ47_02600 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E LCQ47_04450 SMC family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E LCQ47_04455 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E LCQ47_10035 recA; recombinase RecA K03553 recA; recombination protein RecA
E LCQ47_12105 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E LCQ47_07795 recF; DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF
E LCQ47_08615 putative DNA binding domain-containing protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E LCQ47_10340 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E LCQ47_00430 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E LCQ47_07670 recR; recombination mediator RecR K06187 recR; recombination protein RecR
E LCQ47_04620 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E LCQ47_10795 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E LCQ47_10800 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E LCQ47_10790 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E LCQ47_09180 addA; helicase-exonuclease AddAB subunit AddA K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E LCQ47_09175 exodeoxyribonuclease V subunit gamma K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
E LCQ47_02890 cas1c; type I-C CRISPR-associated endonuclease Cas1c K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E LCQ47_04450 SMC family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E LCQ47_04455 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F LCQ47_07215 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F LCQ47_07780 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F LCQ47_00760 topA; type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F LCQ47_02720 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F LCQ47_00430 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F LCQ47_07670 recR; recombination mediator RecR K06187 recR; recombination protein RecR
F LCQ47_01580 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F LCQ47_00140 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F LCQ47_03115 excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F LCQ47_11640 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F LCQ47_11635 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D LCQ47_08725 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D LCQ47_10035 recA; recombinase RecA K03553 recA; recombination protein RecA
D LCQ47_01190 lexA; transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D LCQ47_04620 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D LCQ47_08235 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D LCQ47_10390 dinD; DNA damage-inducible protein D K14623 dinD; DNA-damage-inducible protein D
D LCQ47_10040 recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D LCQ47_05855 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LCQ47_12110 (deoxy)nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LCQ47_08505 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LCQ47_00555 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D LCQ47_09855 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
D LCQ47_00115 bifunctional oligoribonuclease/PAP phosphatase NrnA K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024