+F Repair protein KO
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DNA Repair and Recombination Proteins - Mycobacterium sp. MCS
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Mmcs_2223 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Mmcs_3871 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Mmcs_2038 deoxyribodipyrimidine photo-lyase type I K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E Mmcs_1933 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Mmcs_2956 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E Mmcs_4746 HhH-GPD K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Mmcs_4816 DNA-(apurinic or apyrimidinic site) lyase / endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E Mmcs_4485 type III restriction enzyme, res subunit K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Mmcs_4043 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Mmcs_0543 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Mmcs_3069 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Mmcs_2191 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Mmcs_2223 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Mmcs_3871 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Mmcs_2038 deoxyribodipyrimidine photo-lyase type I K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D Mmcs_2924 deoxyribodipyrimidine photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E Mmcs_1933 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Mmcs_2993 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Mmcs_3957 Uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Mmcs_0026 Uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Mmcs_5490 Uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Mmcs_3870 DNA-3-methyladenine glycosylase II K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E Mmcs_2956 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E Mmcs_4746 HhH-GPD K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Mmcs_4003 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E Mmcs_1950 DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Mmcs_4336 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Mmcs_1265 DNA-formamidopyrimidine glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E Mmcs_4816 DNA-(apurinic or apyrimidinic site) lyase / endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Mmcs_0567 Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E Mmcs_1211 exodeoxyribonuclease III (xth) K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E Mmcs_0972 Endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
D DNA ligase
E Mmcs_1881 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E Mmcs_3011 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E Mmcs_0603 ABC transporter related protein K03701 uvrA; excinuclease ABC subunit A
E Mmcs_2988 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E Mmcs_3001 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E Mmcs_2395 Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E Mmcs_3812 Excinuclease ABC, C subunit-like protein K05984 cho; excinuclease Cho [EC:3.1.25.-]
E Mmcs_4330 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Mmcs_1409 ATP-dependent DNA helicase, Rep family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Mmcs_1404 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Mmcs_3011 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E Mmcs_1881 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F Mmcs_0969 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F Mmcs_0970 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F Mmcs_1113 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F Mmcs_2371 DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F Mmcs_4245 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E Mmcs_4107 Exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E Mmcs_4108 Exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E Mmcs_3087 error-prone DNA polymerase, DnaE-like / DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E Mmcs_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Mmcs_3511 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E Mmcs_4794 DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E Mmcs_4900 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Mmcs_3289 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Mmcs_5482 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Mmcs_4909 DNA polymerase III, tau subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E Mmcs_1881 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E Mmcs_4330 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Mmcs_1409 ATP-dependent DNA helicase, Rep family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Mmcs_1404 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Mmcs_5369 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E Mmcs_3616 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E Mmcs_0818 DNA mismatch endonuclease vsr K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Mmcs_0900 DNA helicase/exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E Mmcs_0901 DNA helicase/exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E Mmcs_0897 DNA helicase/exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E Mmcs_2147 recA protein K03553 recA; recombination protein RecA
E Mmcs_2266 Holliday junction DNA helicase subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Mmcs_2267 Holliday junction DNA helicase subunit RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Mmcs_2265 Holliday junction endonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E Mmcs_2380 replication restart DNA helicase PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E Mmcs_2147 recA protein K03553 recA; recombination protein RecA
E Mmcs_4742 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E Mmcs_0004 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E Mmcs_1936 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Mmcs_3450 DNA replication and repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E Mmcs_4903 DNA replication and repair protein RecR K06187 recR; recombination protein RecR
E Mmcs_2949 DNA replication and repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E Mmcs_2266 Holliday junction DNA helicase subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Mmcs_2267 Holliday junction DNA helicase subunit RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Mmcs_2265 Holliday junction endonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E Mmcs_3639 protein of unknown function DUF853, NPT hydrolase putative K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E Mmcs_4361 DNA end-binding protein Ku K10979 ku; DNA end-binding protein Ku
E Mmcs_4352 ATP-dependent DNA ligase LigD ligase module / ATP-dependent DNA ligase LigD polymerase module / ATP-dependent DNA ligase LigD phosphoesterase module K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E Mmcs_5528 DNA ligase (ATP) K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Mmcs_5343 DNA gyrase/topoisomerase IV, subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Mmcs_0007 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Mmcs_0006 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F Mmcs_5342 DNA topoisomerase (ATP-hydrolyzing) K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F Mmcs_4796 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F Mmcs_1279 conserved hypothetical protein K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F Mmcs_1923 bacterial nucleoid protein Hbs K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F Mmcs_3450 DNA replication and repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F Mmcs_4903 DNA replication and repair protein RecR K06187 recR; recombination protein RecR
F Mmcs_1881 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F Mmcs_4657 ATP-dependent DNA helicase, RecQ-like protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Mmcs_2506 ATP-dependent DNA helicase, RecQ family K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Mmcs_0603 ABC transporter related protein K03701 uvrA; excinuclease ABC subunit A
F Mmcs_2988 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F Mmcs_3001 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D Mmcs_5059 DNA-directed DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D Mmcs_1812 DNA-directed DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D Mmcs_3095 DNA-directed DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D Mmcs_2147 recA protein K03553 recA; recombination protein RecA
D Mmcs_2168 SOS-response transcriptional repressor, LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D Mmcs_2949 DNA replication and repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D Mmcs_1175 conserved hypothetical protein K14161 imuB; protein ImuB
D Mmcs_1183 error-prone DNA polymerase, DnaE-like protein K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D Mmcs_5369 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D Mmcs_3616 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D Mmcs_2148 regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D Mmcs_3855 Helicase c2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D Mmcs_1267 ATP dependent helicase, Lhr family K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D Mmcs_4043 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Mmcs_0543 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Mmcs_3069 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Mmcs_1924 NUDIX hydrolase K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D Mmcs_2943 NUDIX hydrolase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D Mmcs_4021 NUDIX hydrolase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D Mmcs_2191 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Mmcs_1085 Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Mmcs_1817 ribonucleoside-diphosphate reductase class Ib alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Mmcs_1828 ribonucleoside-diphosphate reductase class Ib beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D Mmcs_4214 putative ribonucleoside-diphosphate reductase (beta chain) NrdB (ribonucleotide reductase small chain) K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D Mmcs_2084 phosphoesterase, RecJ-like protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024