+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Marinomonas mediterranea</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
C    Marme_0669 CRISPR-associated protein Cas1	K15342 cas1; CRISP-associated protein Cas1 
C    Marme_3328 CRISPR-associated protein Cas1	K15342 cas1; CRISP-associated protein Cas1 
C    Marme_0668 CRISPR-associated protein Cas2	K09951 cas2; CRISPR-associated protein Cas2 
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
D      Marme_3327 CRISPR-associated helicase Cas3 family	K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] 
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
D      Marme_3325 CRISPR-associated protein, Csy1 family	K19127 csy1; CRISPR-associated protein Csy1 
D      Marme_3324 CRISPR-associated protein, Csy2 family	K19128 csy2; CRISPR-associated protein Csy2 
D      Marme_3323 CRISPR-associated protein, Csy3 family	K19129 csy3; CRISPR-associated protein Csy3 
D      Marme_3322 CRISPR-associated protein, Csy4 family	K19130 csy4; CRISPR-associated endonuclease Csy4 [EC:3.1.-.-] 
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
D      Marme_0677 CRISPR-associated protein TM1795 family protein	K07061 cmr1; CRISPR-associated protein Cmr1 
D      Marme_0676 CRISPR-associated protein, Crm2 family	K19076 cmr2; CRISPR-associated protein Cmr2 
D      Marme_0675 CRISPR-associated protein, Cmr3	K09127 cmr3; CRISPR-associated protein Cmr3 
D      Marme_0674 CRISPR-associated RAMP protein, Cmr4 family	K09000 cmr4; CRISPR-associated protein Cmr4 
D      Marme_0673 CRISPR-associated protein, Cmr5 family	K19141 cmr5; CRISPR-associated protein Cmr5 
D      Marme_0672 CRISPR-associated RAMP protein, Cmr6 family	K19142 cmr6; CRISPR-associated protein Cmr6 
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      Marme_0925 DNA-cytosine methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
D      Marme_4060 DNA-cytosine methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
B  Type III R-M system
B  Type IV R-M system
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
C    YoeB-YefM
D      Marme_0026 addiction module toxin, Txe/YoeB family	K19158 yoeB; toxin YoeB [EC:3.1.-.-] 
D      Marme_3890 addiction module toxin, Txe/YoeB family	K19158 yoeB; toxin YoeB [EC:3.1.-.-] 
D      Marme_0027 prevent-host-death family protein	K19159 yefM; antitoxin YefM 
D      Marme_3884 prevent-host-death family protein	K19159 yefM; antitoxin YefM 
D      Marme_3891 prevent-host-death family protein	K19159 yefM; antitoxin YefM 
C    HipA-HipB
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
D      Marme_0339 phage shock protein B	K03970 pspB; phage shock protein B 
C    CcdB-CcdA
C    ParE-ParD
D      Marme_2802 plasmid stabilization system	K19092 parE1_3_4; toxin ParE1/3/4 
D      Marme_1669 addiction module toxin, RelE/StbE family	K19092 parE1_3_4; toxin ParE1/3/4 
D      Marme_2803 addiction module antidote protein, CC2985 family	K07746 parD1_3_4; antitoxin ParD1/3/4 
C    Doc-Phd
C    HigB-HigA
D      Marme_3518 plasmid maintenance system antidote protein, XRE family	K21498 higA-1; antitoxin HigA-1 
C    MqsR-MqsA
C    VapC-VapB
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    Type II TA system related factors
D      Marme_2517 cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      Marme_1764 cell shape determining protein, MreB/Mrl family	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      Marme_1488 DNA topoisomerase IV, A subunit	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
D      Marme_3335 DNA topoisomerase IV, B subunit	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
D      Marme_1445 glutamyl-tRNA synthetase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
D      Marme_0868 protein of unknown function DUF339	K09159 cptB; antitoxin CptB 
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    Marme_1217 Cysteine desulfurase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023